[{"Gene":"A3GALT2","Gene synonym":["A3GALT2P","IGB3S","IGBS3S"],"Ensembl":"ENSG00000184389","Gene description":"Alpha 1,3-galactosyltransferase 2","Uniprot":["U3KPV4"],"Chromosome":"1","Position":"33306766-33321098","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"}},{"Gene":"A4GALT","Gene synonym":["A14GALT","Gb3S","P(k)","P1"],"Ensembl":"ENSG00000128274","Gene description":"Alpha 1,4-galactosyltransferase (P blood group)","Uniprot":["Q9NPC4"],"Chromosome":"22","Position":"42692121-42721298","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"80.5","Basal respiratory cells":"76.7","Ionocytes":"74.0","Proximal tubular cells":"99.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001141"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"22000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA001141":"AB_1078139"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.48e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"}},{"Gene":"AAAS","Gene synonym":[],"Ensembl":"ENSG00000094914","Gene description":"Aladin WD repeat nucleoporin","Uniprot":["Q9NRG9"],"Chromosome":"12","Position":"53307456-53324864","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040086"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"HPA040086":"AB_10805602"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"}},{"Gene":"AADAC","Gene synonym":["CES5A1","DAC"],"Ensembl":"ENSG00000114771","Gene description":"Arylacetamide deacetylase","Uniprot":["P22760"],"Chromosome":"3","Position":"151814073-151828488","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"224.9","intestine":"241.7","liver":"946.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Hepatocytes":"602.1","Proximal enterocytes":"441.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"22","RNA cancer specific FPKM":{"liver cancer":"153.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"65.8","liver cancer":"44.1"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 2","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002911"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002911":"AB_1078074"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.58e-6"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.02e-4"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.19e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"}},{"Gene":"AADACL3","Gene synonym":[],"Ensembl":"ENSG00000188984","Gene description":"Arylacetamide deacetylase like 3","Uniprot":["Q5VUY0"],"Chromosome":"1","Position":"12716110-12728760","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"1.6","skin 1":"1.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"2.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"2.0"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AADACL4","Gene synonym":[],"Ensembl":"ENSG00000204518","Gene description":"Arylacetamide deacetylase like 4","Uniprot":["Q5VUY2"],"Chromosome":"1","Position":"12644085-12667076","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Bone cancer":"1.0"},"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AAR2","Gene synonym":["bA234K24.2","C20orf4"],"Ensembl":"ENSG00000131043","Gene description":"AAR2 splicing factor","Uniprot":["Q9Y312"],"Chromosome":"20","Position":"36236131-36270918","Protein class":["Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034220","HPA048645"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034220":"AB_1564205","HPA048645":"AB_2680475"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"}},{"Gene":"AATK","Gene synonym":["AATYK","AATYK1","KIAA0641","LMR1","LMTK1","PPP1R77"],"Ensembl":"ENSG00000181409","Gene description":"Apoptosis associated tyrosine kinase","Uniprot":["Q6ZMQ8"],"Chromosome":"17","Position":"81110487-81166221","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"184.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"82.4","Oligodendrocytes":"229.6","Schwann cells":"86.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"neutrophil":"2.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"2.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009073"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA009073":"AB_1078076"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"}},{"Gene":"ABCA1","Gene synonym":["ABC1","HDLDT1","TGD"],"Ensembl":"ENSG00000165029","Gene description":"ATP binding cassette subfamily A member 1","Uniprot":["O95477"],"Chromosome":"9","Position":"104781006-104928155","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Atherosclerosis","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"120.9","Hepatocytes":"136.6","Langerhans cells":"127.5","Macrophages":"110.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"eosinophil":"13.1","neutrophil":"10.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"13.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057283","CAB069889"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB069889":"AB_10002789","HPA057283":"AB_2683396"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"}},{"Gene":"ABCA10","Gene synonym":["EST698739"],"Ensembl":"ENSG00000154263","Gene description":"ATP binding cassette subfamily A member 10","Uniprot":["Q8WWZ4"],"Chromosome":"17","Position":"69147214-69244846","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"18.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"196.5","Excitatory neurons":"90.6","Fibroblasts":"55.6","Inhibitory neurons":"109.9","Late spermatids":"114.7","Leydig cells":"55.0","Microglial cells":"182.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"1.4","Rhabdoid":"1.2"},"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014535"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014535":"AB_1844426"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-3"}},{"Gene":"ABCA12","Gene synonym":["DKFZP434G232","ICR2B","LI2"],"Ensembl":"ENSG00000144452","Gene description":"ATP binding cassette subfamily A member 12","Uniprot":["Q86UK0"],"Chromosome":"2","Position":"214931542-215138626","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"5.7","skin 1":"20.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"12.3","Basal respiratory cells":"7.1","Ionocytes":"6.4","Suprabasal keratinocytes":"33.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"5.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"cerebral cortex":"1.0","hippocampal formation":"1.1"},"Antibody":["HPA078239"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA078239":"AB_2732373"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"}},{"Gene":"ABCA13","Gene synonym":["FLJ33876","FLJ33951"],"Ensembl":"ENSG00000179869","Gene description":"ATP binding cassette subfamily A member 13","Uniprot":[],"Chromosome":"7","Position":"48171458-48647497","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"bone marrow":"44.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Basal respiratory cells":"34.6","Club cells":"22.3","Ionocytes":"68.1","Respiratory ciliated cells":"85.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"2.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"6.1"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063601"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"HPA063601":"AB_2685057"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"}},{"Gene":"ABCA2","Gene synonym":["ABC2"],"Ensembl":"ENSG00000107331","Gene description":"ATP binding cassette subfamily A member 2","Uniprot":["Q9BZC7"],"Chromosome":"9","Position":"137007234-137028922","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"brain":"543.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Oligodendrocytes":"367.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042886"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042886":"AB_2678213"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"ABCA3","Gene synonym":["ABC-C","ABC3","EST111653","LBM180"],"Ensembl":"ENSG00000167972","Gene description":"ATP binding cassette subfamily A member 3","Uniprot":["Q99758"],"Chromosome":"16","Position":"2275881-2340746","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"91.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Alveolar cells type 1":"223.1","Alveolar cells type 2":"528.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007884"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007884":"AB_1078077"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"}},{"Gene":"ABCA4","Gene synonym":["ABCR","ARMD2","CORD3","FFM","RP19","STGD","STGD1"],"Ensembl":"ENSG00000198691","Gene description":"ATP binding cassette subfamily A member 4","Uniprot":["P78363"],"Chromosome":"1","Position":"93992834-94121148","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Transport","Vision"],"Molecular function":["Translocase"],"Disease involvement":["Age-related macular degeneration","Cone-rod dystrophy","Disease variant","Retinitis pigmentosa","Stargardt disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"choroid plexus":"144.6","retina":"461.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"265.4","Rod photoreceptor cells":"526.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"3.1"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"hippocampal formation":"9.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"12.1"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064420","HPA078826"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA064420":null,"HPA078826":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.45e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.72e-4"}},{"Gene":"ABCA5","Gene synonym":["EST90625"],"Ensembl":"ENSG00000154265","Gene description":"ATP binding cassette subfamily A member 5","Uniprot":["Q8WWZ7"],"Chromosome":"17","Position":"69244311-69327244","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"209.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022032","HPA062904"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA022032":"AB_1844427","HPA062904":"AB_2732692"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.97e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"}},{"Gene":"ABCA6","Gene synonym":["EST155051"],"Ensembl":"ENSG00000154262","Gene description":"ATP binding cassette subfamily A member 6","Uniprot":["Q8N139"],"Chromosome":"17","Position":"69078702-69141895","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"77.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"61.6","Fibroblasts":"123.0","Hepatocytes":"86.4","Inhibitory neurons":"76.1","Langerhans cells":"57.8","Microglial cells":"91.2","Schwann cells":"70.7","Theca cells":"55.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"liver cancer":"4.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"2.2","lymphoma":"3.1","pancreatic cancer":"2.1"},"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Liver - Hepatocytes","Pancreas - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064878","HPA067180"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA064878":"AB_2685380","HPA067180":"AB_2685797"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"}},{"Gene":"ABCA7","Gene synonym":["ABCX"],"Ensembl":"ENSG00000064687","Gene description":"ATP binding cassette subfamily A member 7","Uniprot":["Q8IZY2"],"Chromosome":"19","Position":"1039997-1065572","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Phagocytosis","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Alzheimer disease","Amyloidosis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"27.4","pituitary gland":"28.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 1":"129.8","Bipolar cells":"114.1","Cone photoreceptor cells":"117.2","Extravillous trophoblasts":"369.2","Rod photoreceptor cells":"243.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041564"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA041564":"AB_2677550"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.26e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"}},{"Gene":"ABCA8","Gene synonym":["KIAA0822"],"Ensembl":"ENSG00000141338","Gene description":"ATP binding cassette subfamily A member 8","Uniprot":["O94911"],"Chromosome":"17","Position":"68867289-68955392","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"230.3","Leydig cells":"522.6","Microglial cells":"157.8","Oligodendrocytes":"383.9","Schwann cells":"231.7","Sertoli cells":"210.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Rhabdoid":"15.5"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Liver - Hepatocytes","Pancreas - Fibroblasts","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044914"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA044914":"AB_10964859"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-3"}},{"Gene":"ABCA9","Gene synonym":["EST640918"],"Ensembl":"ENSG00000154258","Gene description":"ATP binding cassette subfamily A member 9","Uniprot":["Q8IUA7"],"Chromosome":"17","Position":"68974488-69060949","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"54.7","Fibroblasts":"92.7","Inhibitory neurons":"71.6","Leydig cells":"96.7","Microglial cells":"221.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052113","HPA054823"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA052113":"AB_2732573","HPA054823":"AB_2682615"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-3"}},{"Gene":"ABCB1","Gene synonym":["ABC20","CD243","CLCS","GP170","MDR1","P-gp","PGY1"],"Ensembl":"ENSG00000085563","Gene description":"ATP binding cassette subfamily B member 1","Uniprot":["P08183"],"Chromosome":"7","Position":"87503017-87713323","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"101.7","intestine":"70.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"102.0","Microglial cells":"555.5","Proximal enterocytes":"250.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"14.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"27.2","NK-cell":"17.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"NK-cells":"17.9","T-cells":"27.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"24.8","liver cancer":"18.1"},"RNA tissue cell type enrichment":["Prostate - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"12.2"},"Antibody":["CAB001716","HPA002199","HPA074614"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB001716":null,"HPA002199":"AB_1844428","HPA074614":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.33e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.95e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"}},{"Gene":"ABCB10","Gene synonym":["EST20237","M-ABC2","MTABC2"],"Ensembl":"ENSG00000135776","Gene description":"ATP binding cassette subfamily B member 10","Uniprot":["Q9NRK6"],"Chromosome":"1","Position":"229516582-229558707","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"60.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Erythroid cells":"148.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB044063","CAB044065","HPA055175"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB044063":"AB_353262","CAB044065":"AB_2220666","HPA055175":"AB_2682727"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"}},{"Gene":"ABCB11","Gene synonym":["ABC16","BSEP","PFIC-2","PFIC2","PGY4","SPGP"],"Ensembl":"ENSG00000073734","Gene description":"ATP binding cassette subfamily B member 11","Uniprot":["O95342"],"Chromosome":"2","Position":"168915498-169031324","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Intrahepatic cholestasis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"liver":"80.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"42.3","Hepatocytes":"124.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"87","RNA cancer specific FPKM":{"liver cancer":"6.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"1.8"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019035"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Nucleoplasm","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019035":"AB_1844429"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"}},{"Gene":"ABCB4","Gene synonym":["GBD1","MDR2","MDR3","PFIC-3","PGY3"],"Ensembl":"ENSG00000005471","Gene description":"ATP binding cassette subfamily B member 4","Uniprot":["P21439"],"Chromosome":"7","Position":"87401696-87480435","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Intrahepatic cholestasis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"liver":"123.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Hepatocytes":"204.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"liver cancer":"16.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory B-cell":"4.4","naive B-cell":"8.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"8.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"9.2"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Skin - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049395","HPA053288"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Focal adhesion sites","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Focal adhesion sites","Cytosol"],"Antibody RRID":{"HPA049395":"AB_2680745","HPA053288":"AB_2682102"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"}},{"Gene":"ABCB5","Gene synonym":["ABCB5alpha","ABCB5beta","EST422562"],"Ensembl":"ENSG00000004846","Gene description":"ATP binding cassette subfamily B member 5","Uniprot":["Q2M3G0"],"Chromosome":"7","Position":"20615207-20777038","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"epididymis":"26.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"9.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"melanoma":"5.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"skin cancer":"31.5"},"RNA tissue cell type enrichment":["Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"}},{"Gene":"ABCB6","Gene synonym":["EST45597","MTABC3","umat"],"Ensembl":"ENSG00000115657","Gene description":"ATP binding cassette subfamily B member 6 (Langereis blood group)","Uniprot":["Q9NP58"],"Chromosome":"2","Position":"219209772-219218994","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Dyskeratosis congenita","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"14.2","Excitatory neurons":"12.7","Gastric mucus-secreting cells":"4.8","Inhibitory neurons":"10.6","Oligodendrocyte precursor cells":"13.0","Oligodendrocytes":"5.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046723","HPA058011"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane","Mitochondria","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Plasma membrane","Mitochondria","Cytosol"],"Antibody RRID":{"HPA046723":"AB_10960288","HPA058011":"AB_2683578"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.45e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"}},{"Gene":"ABCB7","Gene synonym":["ABC7","ASAT","Atm1p","EST140535"],"Ensembl":"ENSG00000131269","Gene description":"ATP binding cassette subfamily B member 7","Uniprot":["O75027"],"Chromosome":"X","Position":"75051048-75156732","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034982"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA034982":"AB_10601010"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.31e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"}},{"Gene":"ABCB8","Gene synonym":["EST328128","M-ABC1","MABC1","MITOSUR"],"Ensembl":"ENSG00000197150","Gene description":"ATP binding cassette subfamily B member 8","Uniprot":["Q9NUT2"],"Chromosome":"7","Position":"151028422-151047782","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"83.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045187"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA045187":"AB_10964281"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.91e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.34e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.88e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"ABCB9","Gene synonym":["EST122234"],"Ensembl":"ENSG00000150967","Gene description":"ATP binding cassette subfamily B member 9","Uniprot":["Q9NP78"],"Chromosome":"12","Position":"122920951-122981649","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Peptide transport","Protein transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"20.4","testis":"17.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"45.7","Inhibitory neurons":"40.8","Plasma cells":"111.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.6","memory B-cell":"2.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033052","HPA035113","HPA035114"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB033052":"AB_2273463","HPA035113":"AB_2674470","HPA035114":"AB_10601329"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.65e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"}},{"Gene":"ABCC1","Gene synonym":["GS-X","MRP","MRP1"],"Ensembl":"ENSG00000103222","Gene description":"ATP binding cassette subfamily C member 1","Uniprot":["P33527"],"Chromosome":"16","Position":"15949138-16143257","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Hydrolase","Translocase"],"Disease involvement":["Cancer-related genes","Deafness","FDA approved drug targets","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002380","HPA076011"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA002380":"AB_1844432","HPA076011":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.42e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"}},{"Gene":"ABCC10","Gene synonym":["EST182763","MRP7","SIMRP7"],"Ensembl":"ENSG00000124574","Gene description":"ATP binding cassette subfamily C member 10","Uniprot":["Q5T3U5"],"Chromosome":"6","Position":"43427366-43450427","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041607","HPA045464"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041607":"AB_2677579","HPA045464":"AB_2679336"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"}},{"Gene":"ABCC11","Gene synonym":["MRP8"],"Ensembl":"ENSG00000121270","Gene description":"ATP binding cassette subfamily C member 11","Uniprot":["Q96J66"],"Chromosome":"16","Position":"48165773-48247568","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"breast":"46.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"3.2","Breast glandular cells":"6.2","Early spermatids":"3.4","Hepatocytes":"3.8","Prostatic glandular cells":"5.3","Spermatocytes":"3.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"breast cancer":"8.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"breast cancer":"10.6","prostate cancer":"5.3"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 5: Breast - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-4"}},{"Gene":"ABCC12","Gene synonym":["MRP9"],"Ensembl":"ENSG00000140798","Gene description":"ATP binding cassette subfamily C member 12","Uniprot":["Q96J65"],"Chromosome":"16","Position":"48081006-48156018","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"2.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"4.0","Excitatory neurons":"5.1","Late spermatids":"3.3","Spermatocytes":"5.0","Theca cells":"2.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes","Skin - Outer root sheath cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043100"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043100":"AB_10794922"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"ABCC2","Gene synonym":["CMOAT","cMRP","DJS","MRP2"],"Ensembl":"ENSG00000023839","Gene description":"ATP binding cassette subfamily C member 2","Uniprot":["Q92887"],"Chromosome":"10","Position":"99782640-99852594","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"40.2","liver":"121.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hepatocytes":"215.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"24.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"68.9","Rhabdoid":"77.1"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071145"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA071145":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.93e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"}},{"Gene":"ABCC3","Gene synonym":["cMOAT2","EST90757","MLP2","MOAT-D","MRP3"],"Ensembl":"ENSG00000108846","Gene description":"ATP binding cassette subfamily C member 3","Uniprot":["O15438"],"Chromosome":"17","Position":"50634777-50692253","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"59.1","liver":"50.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"223.3","Distal enterocytes":"196.7","Gastric mucus-secreting cells":"231.9","Hepatocytes":"152.3","Late spermatids":"130.5","Paneth cells":"185.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"5.1","non-classical monocyte":"6.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"6.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate basal glandular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037136","HPA048483"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB037136":"AB_477165","HPA048483":"AB_2680414"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.57e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.68e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"}},{"Gene":"ABCC4","Gene synonym":["EST170205","MOAT-B","MOATB","MRP4"],"Ensembl":"ENSG00000125257","Gene description":"ATP binding cassette subfamily C member 4","Uniprot":["O15439"],"Chromosome":"13","Position":"95019835-95301475","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"41.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Microglial cells":"197.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"prostate cancer":"90.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"65.1"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002476"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli","Golgi apparatus"],"Antibody RRID":{"HPA002476":"AB_1844434"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.89e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.25e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"}},{"Gene":"ABCC5","Gene synonym":["EST277145","MOAT-C","MRP5","SMRP"],"Ensembl":"ENSG00000114770","Gene description":"ATP binding cassette subfamily C member 5","Uniprot":["O15440"],"Chromosome":"3","Position":"183919934-184017939","Protein class":["Cancer-related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"167.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"127.5","Excitatory neurons":"99.9","Inhibitory neurons":"120.2","Rod photoreceptor cells":"124.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044067","HPA052295"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA044067":"AB_2678797","HPA052295":"AB_2681789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.78e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.40e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"}},{"Gene":"ABCC6","Gene synonym":["ARA","EST349056","MLP1","MRP6","PXE","URG7"],"Ensembl":"ENSG00000091262","Gene description":"ATP binding cassette subfamily C member 6","Uniprot":["O95255"],"Chromosome":"16","Position":"16149565-16223522","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Transport","Vision"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"134.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"19.2","Hepatocytes":"47.3","Proximal enterocytes":"23.7","Proximal tubular cells":"45.8","Respiratory ciliated cells":"17.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"16.7","renal cancer":"5.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"3.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"monocytes":"3.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"7.1"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Lung - Alveolar cells type 2","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038105"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA038105":"AB_2675835"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.82e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"}},{"Gene":"ABCC8","Gene synonym":["ABC36","HHF1","HI","HRINS","MRP8","PHHI","SUR","SUR1","TNDM2"],"Ensembl":"ENSG00000006071","Gene description":"ATP binding cassette subfamily C member 8","Uniprot":["Q09428"],"Chromosome":"11","Position":"17392498-17476879","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":["Diabetes mellitus","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"pancreas":"20.1","pituitary gland":"34.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"19.0","Bipolar cells":"47.7","Enteroendocrine cells":"16.7","Excitatory neurons":"47.5","Horizontal cells":"19.2","Inhibitory neurons":"38.4","Oligodendrocyte precursor cells":"37.5","Pancreatic endocrine cells":"30.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"pancreatic cancer":"16.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"thyroid cancer":"5.5"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011451","HPA042318"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"CAB011451":null,"HPA042318":"AB_2677947"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-5"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"}},{"Gene":"ABCC9","Gene synonym":["CMD1O","SUR2"],"Ensembl":"ENSG00000069431","Gene description":"ATP binding cassette subfamily C member 9","Uniprot":["O60706"],"Chromosome":"12","Position":"21797389-21942529","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":["Atrial fibrillation","Cardiomyopathy","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"45.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"69.9","Cardiomyocytes":"37.4","Hepatocytes":"84.2","Sertoli cells":"47.0","Skeletal myocytes":"54.4","Smooth muscle cells":"91.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007279"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007279":"AB_1844435"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.85e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-5"}},{"Gene":"ABCD1","Gene synonym":["adrenoleukodystrophy","ALD","ALDP","AMN"],"Ensembl":"ENSG00000101986","Gene description":"ATP binding cassette subfamily D member 1","Uniprot":["P33897"],"Chromosome":"X","Position":"153724856-153744755","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Hydrolase","Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"36.4","Sertoli cells":"30.4","Syncytiotrophoblasts":"26.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"36.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035214"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035214":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"}},{"Gene":"ABCD2","Gene synonym":["ALDL1","ALDR","ALDRP"],"Ensembl":"ENSG00000173208","Gene description":"ATP binding cassette subfamily D member 2","Uniprot":["Q9UBJ2"],"Chromosome":"12","Position":"39550033-39619803","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Hydrolase","Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"15.7","brain":"8.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"69.3","Bipolar cells":"47.0","Excitatory neurons":"32.7","Inhibitory neurons":"33.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"1.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"4.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"lymphoma":"2.5","Myeloma":"7.6","Neuroblastoma":"3.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Colon - Colon enteroendocrine cells","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"}},{"Gene":"ABCD3","Gene synonym":["PMP70","PXMP1","ZWS2"],"Ensembl":"ENSG00000117528","Gene description":"ATP binding cassette subfamily D member 3","Uniprot":["P28288"],"Chromosome":"1","Position":"94418389-94518666","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Hydrolase","Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"126.6"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032026","HPA032027","CAB032516","CAB075749"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"CAB032516":"AB_2257637","CAB075749":"AB_2665755","HPA032026":"AB_2674117","HPA032027":"AB_10602103"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.16e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.84e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"}},{"Gene":"ABCD4","Gene synonym":["EST352188","P70R","PMP69","PXMP1L"],"Ensembl":"ENSG00000119688","Gene description":"ATP binding cassette subfamily D member 4","Uniprot":["O14678"],"Chromosome":"14","Position":"74285269-74303055","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003396"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003396":"AB_1078078"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-3"}},{"Gene":"ABCG1","Gene synonym":["ABC8"],"Ensembl":"ENSG00000160179","Gene description":"ATP binding cassette subfamily G member 1","Uniprot":["P45844"],"Chromosome":"21","Position":"42199689-42297244","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"121.0","Syncytiotrophoblasts":"77.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"eosinophil":"35.5","neutrophil":"36.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"36.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031470","HPA031471"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA031470":"AB_10599188","HPA031471":"AB_10600201"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.16e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"}},{"Gene":"ABCG2","Gene synonym":["ABCP","BCRP","CD338","EST157481","MXR"],"Ensembl":"ENSG00000118777","Gene description":"ATP binding cassette subfamily G member 2 (Junior blood group)","Uniprot":["Q9UNQ0"],"Chromosome":"4","Position":"88090150-88231628","Protein class":["Cancer-related genes","CD markers","Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"88.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"200.4","Distal enterocytes":"74.3","Extravillous trophoblasts":"90.4","Hofbauer cells":"126.3","Microglial cells":"180.6","Proximal enterocytes":"215.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"9.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"2.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"26.1"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037299","HPA054719"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB037299":"AB_476804","HPA054719":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"}},{"Gene":"ABCG4","Gene synonym":["WHITE2"],"Ensembl":"ENSG00000172350","Gene description":"ATP binding cassette subfamily G member 4","Uniprot":["Q9H172"],"Chromosome":"11","Position":"119149052-119162653","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"52.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"14.4","Cone photoreceptor cells":"55.1","Rod photoreceptor cells":"46.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"1.4"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057635"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057635":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"}},{"Gene":"ABCG5","Gene synonym":["STSL"],"Ensembl":"ENSG00000138075","Gene description":"ATP binding cassette subfamily G member 5","Uniprot":["Q9H222"],"Chromosome":"2","Position":"43812472-43838865","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"69","RNA tissue specific nTPM":{"intestine":"47.8","liver":"62.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"48.7","Paneth cells":"21.1","Proximal enterocytes":"31.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"23","RNA cancer specific FPKM":{"liver cancer":"11.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.60e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"}},{"Gene":"ABCG8","Gene synonym":["GBD4"],"Ensembl":"ENSG00000143921","Gene description":"ATP binding cassette subfamily G member 8","Uniprot":["Q9H221"],"Chromosome":"2","Position":"43831942-43882988","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"40","RNA tissue specific nTPM":{"intestine":"31.5","liver":"63.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"68.3","Paneth cells":"16.5","Proximal enterocytes":"34.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"30","RNA cancer specific FPKM":{"liver cancer":"21.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019556"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA019556":"AB_1844444"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"}},{"Gene":"ABHD1","Gene synonym":["FLJ36128","LABH1"],"Ensembl":"ENSG00000143994","Gene description":"Abhydrolase domain containing 1","Uniprot":["Q96SE0"],"Chromosome":"2","Position":"27123789-27130812","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Serine esterase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"21.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"265.0","Late spermatids":"1040.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"1.0"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044390"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044390":"AB_10959380"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"}},{"Gene":"ABHD12","Gene synonym":["ABHD12A","BEM46L2","C20orf22","dJ965G21.2","DKFZP434P106"],"Ensembl":"ENSG00000100997","Gene description":"Abhydrolase domain containing 12, lysophospholipase","Uniprot":["Q8N2K0"],"Chromosome":"20","Position":"25294742-25390835","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Cataract","Deafness","Disease variant","Neuropathy","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"151.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Lung - Macrophages","Skeletal muscle - Macrophages","Skin - Keratinocyte (granular)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026866"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026866":"AB_1844446"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.81e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.30e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.18e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"}},{"Gene":"ABHD13","Gene synonym":["bA153I24.2","BEM46L1","C13orf6","FLJ14906"],"Ensembl":"ENSG00000139826","Gene description":"Abhydrolase domain containing 13","Uniprot":["Q7L211"],"Chromosome":"13","Position":"108218392-108234243","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032143","HPA032144"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA032143":"AB_2674178","HPA032144":"AB_10602304"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"}},{"Gene":"ABHD14A","Gene synonym":["DKFZP564O243","DORZ1"],"Ensembl":"ENSG00000248487","Gene description":"Abhydrolase domain containing 14A","Uniprot":["Q9BUJ0"],"Chromosome":"3","Position":"51971426-51981199","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"124.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Skin - Fibroblast_2","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038153","HPA056913"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"420000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA038153":"AB_2675868","HPA056913":"AB_2683275"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.72e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"}},{"Gene":"ABHD14A-ACY1","Gene synonym":[],"Ensembl":"ENSG00000114786","Gene description":"ABHD14A-ACY1 readthrough","Uniprot":[],"Chromosome":"3","Position":"51974706-51989183","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"14.6","Proximal enterocytes":"44.2","Proximal tubular cells":"17.4","Rod photoreceptor cells":"14.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036174","HPA036175","HPA038153","HPA071834"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036174":"AB_2674988","HPA036175":"AB_2674989","HPA038153":"AB_2675868","HPA071834":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-4"}},{"Gene":"ABHD16A","Gene synonym":["BAT5","D6S82E","NG26"],"Ensembl":"ENSG00000204427","Gene description":"Abhydrolase domain containing 16A, phospholipase","Uniprot":["O95870"],"Chromosome":"6","Position":"31686955-31703356","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"19.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058606"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"37000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058606":"AB_2683774"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.63e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"}},{"Gene":"ABHD17A","Gene synonym":["C19orf27","FAM108A1","MGC5244"],"Ensembl":"ENSG00000129968","Gene description":"Abhydrolase domain containing 17A, depalmitoylase","Uniprot":["Q96GS6"],"Chromosome":"19","Position":"1876810-1885496","Protein class":["Enzymes","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"404.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043270","HPA047226","HPA069225"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA043270":"AB_2678401","HPA047226":"AB_2679991","HPA069225":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.46e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.76e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"}},{"Gene":"ABHD18","Gene synonym":["C4orf29","FLJ21106"],"Ensembl":"ENSG00000164074","Gene description":"Abhydrolase domain containing 18","Uniprot":["Q0P651"],"Chromosome":"4","Position":"127965306-128039953","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"72.5","Inhibitory neurons":"79.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050168","HPA051676"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA050168":"AB_2681040","HPA051676":"AB_2681571"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.35e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.13e-4"}},{"Gene":"ABHD2","Gene synonym":["LABH2"],"Ensembl":"ENSG00000140526","Gene description":"Abhydrolase domain containing 2, acylglycerol lipase","Uniprot":["P08910"],"Chromosome":"15","Position":"89087459-89202355","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase","Serine esterase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"276.5","Hepatocytes":"335.2","Late spermatids":"508.3","Oligodendrocyte precursor cells":"403.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"69.8","neutrophil":"52.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005999"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA005999":"AB_1078080"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.18e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"}},{"Gene":"ABHD3","Gene synonym":["LABH3"],"Ensembl":"ENSG00000158201","Gene description":"Abhydrolase domain containing 3, phospholipase","Uniprot":["Q8WU67"],"Chromosome":"18","Position":"21650901-21704780","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Phospholipid metabolism"],"Molecular function":["Hydrolase","Serine esterase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"102.4","Syncytiotrophoblasts":"111.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010729"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA010729":"AB_1844449"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.52e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"}},{"Gene":"ABHD6","Gene synonym":[],"Ensembl":"ENSG00000163686","Gene description":"Abhydrolase domain containing 6, acylglycerol lipase","Uniprot":["Q9BV23"],"Chromosome":"3","Position":"58237532-58295693","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"64.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"53.8","Oligodendrocytes":"83.6","Proximal enterocytes":"54.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"57.9"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017283","HPA073225"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA017283":"AB_1844452","HPA073225":"AB_2686583"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.13e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"}},{"Gene":"ABI1","Gene synonym":["ABI-1","E3B1","SSH3BP1"],"Ensembl":"ENSG00000136754","Gene description":"Abl interactor 1","Uniprot":["Q8IZP0"],"Chromosome":"10","Position":"26746593-26861087","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"269.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008375","HPA068407"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"440000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB008375":"AB_592744","HPA068407":"AB_2685983"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"}},{"Gene":"ABLIM1","Gene synonym":["ABLIM","LIMAB1","limatin"],"Ensembl":"ENSG00000099204","Gene description":"Actin binding LIM protein 1","Uniprot":["O14639"],"Chromosome":"10","Position":"114431113-114768061","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"848.4","Cardiomyocytes":"664.3","Peritubular cells":"408.2","Squamous epithelial cells":"488.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"139.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"52.2","NK-cells":"63.6","T-cells":"139.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038951","HPA038952"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038951":"AB_10673017","HPA038952":"AB_10670915"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.72e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"}},{"Gene":"ABO","Gene synonym":["A3GALNT","A3GALT1"],"Ensembl":"ENSG00000175164","Gene description":"ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase","Uniprot":[],"Chromosome":"9","Position":"133233278-133276024","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"13.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"84.8","Enteroendocrine cells":"73.8","Granulosa cells":"63.9","Intestinal goblet cells":"86.4","Proximal enterocytes":"192.1","Undifferentiated cells":"64.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"2.0","naive B-cell":"2.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Gallbladder cancer":"88.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"}},{"Gene":"AC001226.2","Gene synonym":[],"Ensembl":"ENSG00000283208","Gene description":"Novel protein","Uniprot":[],"Chromosome":"13","Position":"76992078-77129589","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"4.4","brain":"3.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"4.6","Early spermatids":"1.8","Horizontal cells":"5.1"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC002456.2","Gene synonym":[],"Ensembl":"ENSG00000251154","Gene description":"Uncharacterized LOC102723899","Uniprot":[],"Chromosome":"7","Position":"90469639-90513397","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"69","RNA tissue specific nTPM":{"testis":"9.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Early spermatids":"82.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC004691.2","Gene synonym":[],"Ensembl":"ENSG00000250424","Gene description":"Novel protein, MINDY4 and AQP1 readthrough","Uniprot":[],"Chromosome":"7","Position":"30852273-30923812","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019206","HPA030130"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":null,"Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA019206":"AB_1844965","HPA030130":"AB_10601565"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"}},{"Gene":"AC004832.3","Gene synonym":[],"Ensembl":"ENSG00000249590","Gene description":"Novel SEC14-like 2 (S. cerevisiae) (SEC14L2) and mitochondrial protein 18 kDa (MTP18) protein","Uniprot":[],"Chromosome":"22","Position":"30409255-30428990","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"6.8"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"1.1","testis cancer":"1.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC005551.1","Gene synonym":[],"Ensembl":"ENSG00000284638","Gene description":"Novel protein","Uniprot":[],"Chromosome":"19","Position":"3482804-3483446","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"3.3","intestine":"12.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7","Enteroendocrine cells":"1.2","Gastric mucus-secreting cells":"1.8","Rod photoreceptor cells":"1.1"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC006538.2","Gene synonym":[],"Ensembl":"ENSG00000267001","Gene description":"Novel protein","Uniprot":[],"Chromosome":"19","Position":"2717769-2740048","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"6.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"3.2","Basal squamous epithelial cells":"3.4","Erythroid cells":"8.7","Gastric mucus-secreting cells":"4.2","Plasma cells":"5.8","Squamous epithelial cells":"7.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058526"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058526":"AB_2683743"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC007040.2","Gene synonym":[],"Ensembl":"ENSG00000258881","Gene description":"Novel protein","Uniprot":[],"Chromosome":"2","Position":"70939318-70995336","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.2","retina":"1.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"3.8","Cone photoreceptor cells":"3.4","Horizontal cells":"4.5","Rod photoreceptor cells":"17.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"2.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"AC007846.2","Gene synonym":[],"Ensembl":"ENSG00000285471","Gene description":"Novel protein","Uniprot":[],"Chromosome":"17","Position":"5772926-6080792","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Sarcoma":"15.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC008397.1","Gene synonym":[],"Ensembl":"ENSG00000284797","Gene description":"Novel protein","Uniprot":[],"Chromosome":"19","Position":"18249950-18255419","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"3.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"250.2","Enteroendocrine cells":"47.1","Intestinal goblet cells":"44.4","Paneth cells":"204.6","Proximal enterocytes":"72.0","Undifferentiated cells":"59.4"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Esophageal cancer":"7.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC008676.3","Gene synonym":[],"Ensembl":"ENSG00000285868","Gene description":"Novel protein","Uniprot":[],"Chromosome":"5","Position":"157341596-157460100","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.7","retina":"1.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.7","Horizontal cells":"1.3","Rod photoreceptor cells":"1.0"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC008695.1","Gene synonym":[],"Ensembl":"ENSG00000273217","Gene description":"Novel protein","Uniprot":[],"Chromosome":"5","Position":"131425891-131796983","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"8.2"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037982","HPA037983"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":null,"Subcellular main location":["Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA037982":"AB_10670535","HPA037983":"AB_2675769"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC009163.5","Gene synonym":[],"Ensembl":"ENSG00000261717","Gene description":"Novel TMEM170A-CFDP1 readthrough protein","Uniprot":[],"Chromosome":"16","Position":"75412684-75464706","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.8","skeletal muscle":"2.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"3.7","Basal squamous epithelial cells":"3.6","Erythroid cells":"1.5","Gastric mucus-secreting cells":"3.6","Macrophages":"1.9","Plasma cells":"6.9","Squamous epithelial cells":"3.5","T-cells":"1.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"white matter":"4.8"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041316"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041316":"AB_10794371"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC010319.2","Gene synonym":[],"Ensembl":"ENSG00000269035","Gene description":"Novel protein","Uniprot":[],"Chromosome":"19","Position":"17436611-17460804","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041580"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA041580":"AB_10795700"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC010325.1","Gene synonym":[],"Ensembl":"ENSG00000261341","Gene description":"Uncharacterized LOC105372440","Uniprot":[],"Chromosome":"19","Position":"50776141-50793142","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"testis":"216.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Late spermatids":"4511.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"}},{"Gene":"AC011448.1","Gene synonym":[],"Ensembl":"ENSG00000258674","Gene description":"Novel protein","Uniprot":[],"Chromosome":"19","Position":"19516227-19536076","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cardiomyocytes":"3.7","Late spermatids":"5.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"}},{"Gene":"AC018709.1","Gene synonym":[],"Ensembl":"ENSG00000272297","Gene description":"Novel protein","Uniprot":[],"Chromosome":"4","Position":"186426546-186555328","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"testis":"30.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"4.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC018755.2","Gene synonym":[],"Ensembl":"ENSG00000268500","Gene description":"Novel transcript, sense intronic to AC018755.18","Uniprot":[],"Chromosome":"19","Position":"51612091-51646889","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"26.1","lymphoid tissue":"7.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"5.0"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"180.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"180.3","monocytes":"70.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Leukemia":"3.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009085"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA009085":"AB_1079965"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC020907.6","Gene synonym":[],"Ensembl":"ENSG00000285526","Gene description":"Novel protein","Uniprot":[],"Chromosome":"19","Position":"35106510-35124297","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.3","choroid plexus":"3.1","salivary gland":"7.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"5.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"3.8"},"Antibody":["HPA010856"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":null,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA010856":"AB_1078915"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC024592.3","Gene synonym":[],"Ensembl":"ENSG00000267740","Gene description":"Novel protein","Uniprot":[],"Chromosome":"19","Position":"5866171-5903787","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"1.3","Cardiomyocytes":"2.2","Erythroid cells":"1.1","Plasma cells":"3.6","Squamous epithelial cells":"3.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072209"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA072209":"AB_2686495"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC024598.1","Gene synonym":[],"Ensembl":"ENSG00000285837","Gene description":"Novel protein","Uniprot":[],"Chromosome":"10","Position":"62374192-62672011","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"1.4"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052446"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Centriolar satellite","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":null,"Subcellular main location":["Vesicles","Centriolar satellite","Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA052446":"AB_2681836"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC026316.4","Gene synonym":[],"Ensembl":"ENSG00000285218","Gene description":"Novel protein","Uniprot":[],"Chromosome":"3","Position":"170418868-170860380","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"43.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC048338.2","Gene synonym":[],"Ensembl":"ENSG00000284934","Gene description":"Novel protein","Uniprot":[],"Chromosome":"12","Position":"122207662-122227534","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"3.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"Neuroblastoma":"8.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC055839.2","Gene synonym":[],"Ensembl":"ENSG00000286190","Gene description":"Uncharacterized LOC728392","Uniprot":[],"Chromosome":"17","Position":"5499427-5501006","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"317.6","choroid plexus":"86.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"15.8","Early spermatids":"8.4","Excitatory neurons":"27.8","Inhibitory neurons":"19.5","Late spermatids":"9.6","Microglial cells":"10.0","Oligodendrocyte precursor cells":"11.6","Oligodendrocytes":"7.6","Thymic epithelial cells":"8.4"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"4.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"4.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"46.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC064824.1","Gene synonym":[],"Ensembl":"ENSG00000288695","Gene description":"Novel protein, SRD5A3-RP11-177J6.1 readthrough","Uniprot":[],"Chromosome":"4","Position":"55346228-55388368","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.9","skeletal muscle":"2.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"1.8","Club cells":"2.4","dendritic cells":"2.2","granulocytes":"1.6","Ionocytes":"4.9","Respiratory ciliated cells":"3.7"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC068580.4","Gene synonym":[],"Ensembl":"ENSG00000250644","Gene description":"Novel protein","Uniprot":[],"Chromosome":"11","Position":"1734821-1763954","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adrenal gland":"202.9","liver":"54.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"5.1","Macrophages":"3.5","Respiratory ciliated cells":"2.8","Salivary duct cells":"3.3","Skeletal myocytes":"4.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003001"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003001":"AB_1078404"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"}},{"Gene":"AC068775.1","Gene synonym":[],"Ensembl":"ENSG00000255641","Gene description":"Novel protein","Uniprot":[],"Chromosome":"12","Position":"10412312-10436001","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.1","choroid plexus":"2.5","lymphoid tissue":"5.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"3.3","T-cells":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"NK-cell":"134.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"NK-cells":"134.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"3.4","thyroid cancer":"3.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062570"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062570":"AB_2684795"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC083977.1","Gene synonym":[],"Ensembl":"ENSG00000286131","Gene description":"Novel protein","Uniprot":[],"Chromosome":"8","Position":"32647202-32647390","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"1.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC092143.1","Gene synonym":[],"Ensembl":"ENSG00000198211","Gene description":"Novel protein (MC1R-TUBB3 readthrough)","Uniprot":[],"Chromosome":"16","Position":"89919165-89936092","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"testis":"6.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"2.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011512","HPA043640","HPA046280"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytokinetic bridge","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":null,"Subcellular main location":["Microtubules"],"Subcellular additional location":["Cytokinetic bridge","Mitotic spindle"],"Antibody RRID":{"CAB011512":"AB_444319","HPA043640":"AB_2678594","HPA046280":"AB_2679612"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-4"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC092442.1","Gene synonym":[],"Ensembl":"ENSG00000284684","Gene description":"Novel protein","Uniprot":[],"Chromosome":"4","Position":"6064977-6070162","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"brain":"6.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"amygdala":"1.8","basal ganglia":"6.0","cerebral cortex":"3.7","hippocampal formation":"1.9","hypothalamus":"2.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC092718.2","Gene synonym":[],"Ensembl":"ENSG00000260643","Gene description":"Novel protein","Uniprot":[],"Chromosome":"16","Position":"81053587-81096296","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"8.1","Endometrial ciliated cells":"3.6","Late spermatids":"5.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041368"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041368":"AB_10804001"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"}},{"Gene":"AC093512.2","Gene synonym":[],"Ensembl":"ENSG00000285043","Gene description":"Uncharaterized LOC112694756","Uniprot":[],"Chromosome":"16","Position":"30053090-30070420","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"tongue":"94.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"4.1","Basal squamous epithelial cells":"2.0","Cone photoreceptor cells":"1.7","Erythroid cells":"2.7","Gastric mucus-secreting cells":"2.4","Plasma cells":"6.9","Squamous epithelial cells":"1.6","T-cells":"2.7"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC093668.1","Gene synonym":[],"Ensembl":"ENSG00000270249","Gene description":"Novel protein","Uniprot":[],"Chromosome":"7","Position":"102541501-102592444","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046970"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":null,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA046970":"AB_2679882"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC097636.1","Gene synonym":[],"Ensembl":"ENSG00000285749","Gene description":"Novel protein","Uniprot":[],"Chromosome":"3","Position":"51798803-51833389","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.5","testis":"3.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"93","RNA single cell type specific nTPM":{"Early spermatids":"86.2","Late spermatids":"106.7"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC097637.1","Gene synonym":[],"Ensembl":"ENSG00000173366","Gene description":"Novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein","Uniprot":[],"Chromosome":"3","Position":"52221081-52231190","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"1.8","lymphoid tissue":"2.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC099489.1","Gene synonym":[],"Ensembl":"ENSG00000188897","Gene description":"Novel lipoprotein amino terminal region containing protein","Uniprot":[],"Chromosome":"16","Position":"11359845-11527245","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"18.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"5.0","Langerhans cells":"6.5","Mucus glandular cells":"14.1","Oligodendrocyte precursor cells":"5.8","Salivary duct cells":"5.1","Skeletal myocytes":"8.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"neutrophil":"3.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"granulocytes":"3.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"3.5"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042154"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042154":"AB_2677877"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-5"}},{"Gene":"AC100868.1","Gene synonym":[],"Ensembl":"ENSG00000258417","Gene description":"Novel protein","Uniprot":[],"Chromosome":"8","Position":"132024238-132085655","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC104389.6","Gene synonym":[],"Ensembl":"ENSG00000284931","Gene description":"Novel protein","Uniprot":[],"Chromosome":"11","Position":"5248270-5254783","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"placenta":"4358.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Erythroid cells":"1.1"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"64","RNA cell line specific nTPM":{"Leukemia":"2031.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043234"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043234":"AB_2678378"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC106873.8","Gene synonym":[],"Ensembl":"ENSG00000288635","Gene description":"Novel protein, readthrough ST7-OT4 - ST7","Uniprot":[],"Chromosome":"7","Position":"116954391-117119719","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"13.5"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC117378.1","Gene synonym":[],"Ensembl":"ENSG00000285625","Gene description":"Novel protein","Uniprot":[],"Chromosome":"12","Position":"56714612-56741535","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.2","skeletal muscle":"3.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073152"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":null,"Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA073152":"AB_2686575"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC117457.1","Gene synonym":[],"Ensembl":"ENSG00000275163","Gene description":"Potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript)","Uniprot":[],"Chromosome":"3","Position":"178419123-178843300","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"fallopian tube":"5.6","kidney":"1.5"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"lung cancer":"1.2","Rhabdoid":"2.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC118470.1","Gene synonym":[],"Ensembl":"ENSG00000239395","Gene description":"Novel protein","Uniprot":[],"Chromosome":"1","Position":"247711813-247723764","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"testis":"1.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Early spermatids":"1.4","Late spermatids":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC118553.2","Gene synonym":[],"Ensembl":"ENSG00000283761","Gene description":"Novel protein","Uniprot":[],"Chromosome":"1","Position":"99970011-100083321","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"5.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073681"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA073681":"AB_2686625"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC127029.3","Gene synonym":[],"Ensembl":"ENSG00000285947","Gene description":"Novel protein","Uniprot":[],"Chromosome":"17","Position":"63917203-63931385","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"14.0","naive B-cell":"18.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"18.4"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009178","HPA043715"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":null,"Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA009178":"AB_1078483","HPA043715":"AB_2678632"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC129492.3","Gene synonym":[],"Ensembl":"ENSG00000263620","Gene description":"Novel protein","Uniprot":[],"Chromosome":"17","Position":"8150816-8162975","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"81.6","skeletal muscle":"32.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"35.5","Basal squamous epithelial cells":"50.8","Gastric mucus-secreting cells":"22.7","Plasma cells":"42.5","Squamous epithelial cells":"37.3","T-cells":"23.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC131160.1","Gene synonym":[],"Ensembl":"ENSG00000283765","Gene description":"Presenilin associated rhomboid like","Uniprot":[],"Chromosome":"3","Position":"183815568-183884889","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"9.2","skeletal muscle":"5.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"37","RNA single cell type specific nTPM":{"Astrocytes":"17.4","Excitatory neurons":"23.0","Inhibitory neurons":"23.5","Microglial cells":"32.8","Oligodendrocyte precursor cells":"16.4","Oligodendrocytes":"26.4"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019545"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA019545":"AB_1855796"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC134669.1","Gene synonym":[],"Ensembl":"ENSG00000265118","Gene description":"Novel protein","Uniprot":[],"Chromosome":"17","Position":"31305213-31318831","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.9","lymphoid tissue":"8.4"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"220.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"1.8","lymphoma":"1.9","Myeloma":"2.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045033"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045033":"AB_2679191"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC134980.2","Gene synonym":[],"Ensembl":"ENSG00000285472","Gene description":"Novel protein","Uniprot":[],"Chromosome":"15","Position":"22015233-22095857","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"48","RNA tissue specific nTPM":{"testis":"4.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"17.8","Late spermatids":"8.3"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057442"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA057442":"AB_2683442"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC135050.2","Gene synonym":[],"Ensembl":"ENSG00000255439","Gene description":"Novel protein, VKORC1 and PRSS53 readthrough","Uniprot":[],"Chromosome":"16","Position":"31083439-31094956","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"1.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"13.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042720"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA042720":"AB_10961864"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-6"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-4"}},{"Gene":"AC136475.9","Gene synonym":[],"Ensembl":"ENSG00000288681","Gene description":"Novel protein","Uniprot":[],"Chromosome":"11","Position":"308408-315272","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"4.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"4.1","hippocampal formation":"1.7"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"473.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"473.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"68","RNA cell line specific nTPM":{"Bile duct cancer":"7.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC136616.1","Gene synonym":[],"Ensembl":"ENSG00000273554","Gene description":"","Uniprot":[],"Chromosome":"Unmapped","Position":"1139577-1147868","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"1.3","testis":"3.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"5.6","Late spermatids":"8.9","Spermatocytes":"5.0"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC138811.2","Gene synonym":[],"Ensembl":"ENSG00000260342","Gene description":"Novel protein","Uniprot":[],"Chromosome":"16","Position":"18788063-18801519","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"14.8"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045307"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":null,"Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA045307":"AB_10961042"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"}},{"Gene":"AC138894.1","Gene synonym":[],"Ensembl":"ENSG00000261832","Gene description":"Novel protein","Uniprot":[],"Chromosome":"16","Position":"28456371-28492098","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"3.1","Early spermatids":"7.1","Late spermatids":"13.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"}},{"Gene":"AC138969.1","Gene synonym":[],"Ensembl":"ENSG00000183889","Gene description":"Novel member of the nuclear pore complex interacting protein NPIP gene family","Uniprot":[],"Chromosome":"16","Position":"16317444-16350590","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-7"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"}},{"Gene":"AC144573.1","Gene synonym":[],"Ensembl":"ENSG00000285880","Gene description":"ADRB3-GOT1L1 readthrough","Uniprot":[],"Chromosome":"8","Position":"37934340-37965953","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"3.9","Enteroendocrine cells":"1.2"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061969"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA061969":"AB_2732674"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC171558.1","Gene synonym":[],"Ensembl":"ENSG00000274792","Gene description":"Olfactory receptor 4N4-like","Uniprot":[],"Chromosome":"Unmapped","Position":"386278-387620","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057442"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA057442":"AB_2683442"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC171558.3","Gene synonym":[],"Ensembl":"ENSG00000275249","Gene description":"","Uniprot":[],"Chromosome":"Unmapped","Position":"372322-373405","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058889"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058889":"AB_2683845"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AC231657.3","Gene synonym":[],"Ensembl":"ENSG00000288053","Gene description":"Novel protein","Uniprot":[],"Chromosome":"X","Position":"49071470-49079887","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1.0"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ACAD10","Gene synonym":["MGC5601"],"Ensembl":"ENSG00000111271","Gene description":"Acyl-CoA dehydrogenase family member 10","Uniprot":["Q6JQN1"],"Chromosome":"12","Position":"111686053-111757107","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067222"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA067222":"AB_2685805"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.71e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"}},{"Gene":"ACADM","Gene synonym":["ACAD1","MCAD","MCADH"],"Ensembl":"ENSG00000117054","Gene description":"Acyl-CoA dehydrogenase medium chain","Uniprot":["P11310"],"Chromosome":"1","Position":"75724431-75787575","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"367.3","skeletal muscle":"380.0","tongue":"475.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"640.9","Distal tubular cells":"236.3","Hepatocytes":"282.5","Proximal tubular cells":"529.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Skeletal muscle - Skeletal myocytes","Skin - Sebaceous gland cells","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006198","HPA026542"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"930000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA006198":"AB_1078087","HPA026542":"AB_1844469"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.30e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.83e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"}},{"Gene":"ACBD4","Gene synonym":["FLJ13322"],"Ensembl":"ENSG00000181513","Gene description":"Acyl-CoA binding domain containing 4","Uniprot":["Q8NC06"],"Chromosome":"17","Position":"45132600-45144181","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"93.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"55.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051772"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA051772":"AB_2681603"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.76e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.64e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.53e-4"}},{"Gene":"ACBD5","Gene synonym":["DKFZp434A2417","KIAA1996"],"Ensembl":"ENSG00000107897","Gene description":"Acyl-CoA binding domain containing 5","Uniprot":["Q5T8D3"],"Chromosome":"10","Position":"27168135-27243046","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy","Transport"],"Molecular function":null,"Disease involvement":["Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"157.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011861","HPA012145"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA011861":"AB_1844493","HPA012145":"AB_1844494"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.33e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.68e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-3"}},{"Gene":"ACE","Gene synonym":["ACE1","CD143","DCP1"],"Ensembl":"ENSG00000159640","Gene description":"Angiotensin I converting enzyme","Uniprot":["P12821"],"Chromosome":"17","Position":"63477061-63498380","Protein class":["Candidate cardiovascular disease genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"265.1","testis":"101.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Early spermatids":"366.7","Late spermatids":"1337.4","Proximal enterocytes":"1054.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"8.1"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"17.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Skin - Fibroblast_1","Testis - Late spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002426","CAB002921","HPA029298","HPA069790"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":104000000,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB002426":"AB_442052","CAB002921":null,"HPA029298":"AB_10960255","HPA069790":"AB_2686197"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"}},{"Gene":"ACE2","Gene synonym":[],"Ensembl":"ENSG00000130234","Gene description":"Angiotensin I converting enzyme 2","Uniprot":["Q9BYF1"],"Chromosome":"X","Position":"15494566-15607236","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Carboxypeptidase","Host cell receptor for virus entry","Hydrolase","Metalloprotease","Protease","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"65.5","intestine":"242.2","kidney":"87.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Proximal enterocytes":"204.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"13.9","renal cancer":"26.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"6.8"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000288","CAB026174","CAB026213","CAB080024","CAB080025","CAB080027","CAB080028"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":4530000,"Blood concentration - Conc. blood MS [pg\/L]":"400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026174":null,"CAB026213":null,"CAB080024":"AB_10864415","CAB080025":"AB_2809589","CAB080027":"AB_2665870","CAB080028":"AB_2665871","HPA000288":"AB_1078160"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.21e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"}},{"Gene":"ACER1","Gene synonym":["ASAH3"],"Ensembl":"ENSG00000167769","Gene description":"Alkaline ceramidase 1","Uniprot":["Q8TDN7"],"Chromosome":"19","Position":"6306142-6333612","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"skin 1":"88.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"16.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"head and neck cancer":"1.0","melanoma":"2.2","prostate cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"1.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"1.3"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-4"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"}},{"Gene":"ACER2","Gene synonym":["ALKCDase2","ASAH3L","FLJ41587"],"Ensembl":"ENSG00000177076","Gene description":"Alkaline ceramidase 2","Uniprot":["Q5QJU3"],"Chromosome":"9","Position":"19409009-19452505","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"stomach 1":"61.8","urinary bladder":"39.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"19.5","Gastric mucus-secreting cells":"73.3","Microglial cells":"25.5","Syncytiotrophoblasts":"12.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"15.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Kidney - Endothelial cells","Skeletal muscle - Endothelial cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-3"}},{"Gene":"ACER3","Gene synonym":["APHC","FLJ11238","PHCA"],"Ensembl":"ENSG00000078124","Gene description":"Alkaline ceramidase 3","Uniprot":["Q9NUN7"],"Chromosome":"11","Position":"76860859-77026797","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"152.6","Oligodendrocytes":"316.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Skeletal muscle - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070087"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA070087":"AB_2732147"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"}},{"Gene":"ACHE","Gene synonym":["YT"],"Ensembl":"ENSG00000087085","Gene description":"Acetylcholinesterase (Cartwright blood group)","Uniprot":["P22303"],"Chromosome":"7","Position":"100889994-100896974","Protein class":["Blood group antigen proteins","Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Neurotransmitter degradation"],"Molecular function":["Blood group antigen","Hydrolase","Serine esterase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"98.2","skeletal muscle":"163.2","tongue":"48.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"29.4","Erythroid cells":"33.3","Exocrine glandular cells":"50.1","Horizontal cells":"60.2","Paneth cells":"40.3","Proximal enterocytes":"39.9","Skeletal myocytes":"81.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027098"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"990000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA027098":"AB_2672111"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.27e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.88e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"}},{"Gene":"ACKR1","Gene synonym":["CCBP1","CD234","DARC","Dfy","FY","GPD"],"Ensembl":"ENSG00000213088","Gene description":"Atypical chemokine receptor 1 (Duffy blood group)","Uniprot":["Q16570"],"Chromosome":"1","Position":"159203307-159206500","Protein class":["Blood group antigen proteins","CD markers","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Blood group antigen","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"320.5","breast":"278.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Adipocytes":"579.9","Endothelial cells":"700.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bile duct cancer":"5.7","Brain cancer":"2.0","Leukemia":"1.5","Neuroblastoma":"2.1","skin cancer":"2.7"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016421","HPA017672"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016421":"AB_1849219","HPA017672":"AB_1849221"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.52e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.76e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"}},{"Gene":"ACKR2","Gene synonym":["CCBP2","CCR10","CCR9","CMKBR9","D6"],"Ensembl":"ENSG00000144648","Gene description":"Atypical chemokine receptor 2","Uniprot":["O00590"],"Chromosome":"3","Position":"42804752-42887974","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Inflammatory response"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"9.4","placenta":"16.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cytotrophoblasts":"33.6","Extravillous trophoblasts":"118.1","Syncytiotrophoblasts":"79.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"eosinophil":"3.9","NK-cell":"1.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"3.9","NK-cells":"1.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"amygdala":"2.2","basal ganglia":"7.9","cerebral cortex":"4.9","hippocampal formation":"2.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013819","HPA073493"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA013819":"AB_1846126","HPA073493":"AB_2686610"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"}},{"Gene":"ACKR3","Gene synonym":["CMKOR1","CXCR7","GPR159","RDC1"],"Ensembl":"ENSG00000144476","Gene description":"Atypical chemokine receptor 3","Uniprot":["P25106"],"Chromosome":"2","Position":"236567787-236582354","Protein class":["Cancer-related genes","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"35.7","Endothelial cells":"42.3","Fibroblasts":"146.8","Smooth muscle cells":"51.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"NK-cells":"4.7","T-cells":"3.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032003","HPA049718"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA032003":"AB_2674107","HPA049718":"AB_2680859"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.76e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.01e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.93e-4"}},{"Gene":"ACKR4","Gene synonym":["CCBP2","CCR11","CCRL1","CCX-CKR","PPR1","VSHK1"],"Ensembl":"ENSG00000129048","Gene description":"Atypical chemokine receptor 4","Uniprot":["Q9NPB9"],"Chromosome":"3","Position":"132597270-132618967","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"15.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"17.2","Exocrine glandular cells":"10.5","Fibroblasts":"18.0","Proximal enterocytes":"20.3","Respiratory ciliated cells":"24.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"2.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"4.7"},"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"cerebellum":"4.7","pons and medulla":"1.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054926"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA054926":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"}},{"Gene":"ACO2","Gene synonym":["ACONM"],"Ensembl":"ENSG00000100412","Gene description":"Aconitase 2","Uniprot":["Q99798"],"Chromosome":"22","Position":"41447830-41529273","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tricarboxylic acid cycle"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"567.7","skeletal muscle":"660.4","tongue":"695.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"391.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001097"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA001097":"AB_1078092"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"}},{"Gene":"ACOT1","Gene synonym":["ACH2","CTE-1","LACH2"],"Ensembl":"ENSG00000184227","Gene description":"Acyl-CoA thioesterase 1","Uniprot":["Q86TX2"],"Chromosome":"14","Position":"73537143-73543796","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Hydrolase","Serine esterase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"44.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"10.4","Excitatory neurons":"13.6","Inhibitory neurons":"11.7","Oligodendrocyte precursor cells":"8.2","Oligodendrocytes":"14.2","Proximal tubular cells":"5.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043705"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA043705":"AB_2678626"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.09e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"}},{"Gene":"ACOT2","Gene synonym":["Mte1","ZAP128"],"Ensembl":"ENSG00000119673","Gene description":"Acyl-CoA thioesterase 2","Uniprot":["P49753"],"Chromosome":"14","Position":"73567620-73575658","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Hydrolase","Serine esterase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"118.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"35.4","Hepatocytes":"29.0","Proximal tubular cells":"48.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Prostate - Smooth muscle cells","Skin - Sebaceous gland cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043705","HPA060170"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA043705":"AB_2678626","HPA060170":"AB_2732642"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.28e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-1"}},{"Gene":"ACOT4","Gene synonym":["FLJ31235","PTE-Ib","PTE2B"],"Ensembl":"ENSG00000177465","Gene description":"Acyl-CoA thioesterase 4","Uniprot":["Q8N9L9"],"Chromosome":"14","Position":"73591873-73595766","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Hydrolase","Serine esterase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"15.0","liver":"16.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"30.2","Proximal enterocytes":"19.5","Proximal tubular cells":"48.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"12.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Lung - Macrophages","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000779"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000779":"AB_1078093"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.77e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"}},{"Gene":"ACOT6","Gene synonym":["C14orf42"],"Ensembl":"ENSG00000205669","Gene description":"Acyl-CoA thioesterase 6","Uniprot":["Q3I5F7"],"Chromosome":"14","Position":"73610945-73619888","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Serine esterase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.0","kidney":"3.7","liver":"3.1","skeletal muscle":"4.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"2.2","Excitatory neurons":"2.7","Hepatocytes":"4.2","Inhibitory neurons":"2.8","Proximal tubular cells":"4.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"5.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"1.9"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058258"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058258":"AB_2683656"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-1"}},{"Gene":"ACP2","Gene synonym":["LAP"],"Ensembl":"ENSG00000134575","Gene description":"Acid phosphatase 2, lysosomal","Uniprot":["P11117"],"Chromosome":"11","Position":"47239302-47248906","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"78.1","Hofbauer cells":"102.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"69.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"69.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"}},{"Gene":"ACP3","Gene synonym":["ACP-3","ACPP","PAP","TM-PAP"],"Ensembl":"ENSG00000014257","Gene description":"Acid phosphatase 3","Uniprot":["P15309"],"Chromosome":"3","Position":"132317369-132368298","Protein class":["Cancer-related genes","Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"76","RNA tissue specific nTPM":{"prostate":"3643.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"444","RNA single cell type specific nTPM":{"Prostatic glandular cells":"16978.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"275","RNA cancer specific FPKM":{"prostate cancer":"1227.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"139.7"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"granulocytes":"139.7"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"38","RNA cell line specific nTPM":{"prostate cancer":"274.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Breast glandular cells","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000071","HPA004335","HPA063916"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":460000,"Blood concentration - Conc. blood MS [pg\/L]":"480000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000071":null,"HPA004335":"AB_1079684","HPA063916":"AB_2685152"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"}},{"Gene":"ACP4","Gene synonym":["ACPT"],"Ensembl":"ENSG00000142513","Gene description":"Acid phosphatase 4","Uniprot":["Q9BZG2"],"Chromosome":"19","Position":"50790415-50795219","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Amelogenesis imperfecta","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"1.2","testis":"3.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Late spermatids":"351.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"3.8"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"ACSBG1","Gene synonym":["BG1","BGM","FLJ30320","hBG1","hsBG","KIAA0631","MGC14352"],"Ensembl":"ENSG00000103740","Gene description":"Acyl-CoA synthetase bubblegum family member 1","Uniprot":["Q96GR2"],"Chromosome":"15","Position":"78167468-78245688","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"56.6","skin 1":"14.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"153.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"3.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041642","CAB045955","HPA058869"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB045955":"AB_11124196","HPA041642":"AB_2677593","HPA058869":"AB_2683840"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"}},{"Gene":"ACSBG2","Gene synonym":["BGR","DKFZp434K1635","PRTD-NY3"],"Ensembl":"ENSG00000130377","Gene description":"Acyl-CoA synthetase bubblegum family member 2","Uniprot":["Q5FVE4"],"Chromosome":"19","Position":"6135247-6193094","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Fatty acid metabolism","Lipid metabolism","Spermatogenesis"],"Molecular function":["Developmental protein","Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"89","RNA tissue specific nTPM":{"testis":"129.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"1766.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043421","HPA051013"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043421":"AB_10794182","HPA051013":"AB_2681311"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-4"}},{"Gene":"ACSL1","Gene synonym":["ACS1","FACL1","FACL2","LACS","LACS1","LACS2"],"Ensembl":"ENSG00000151726","Gene description":"Acyl-CoA synthetase long chain family member 1","Uniprot":["P33121"],"Chromosome":"4","Position":"184755595-184826818","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"770.4","liver":"1319.0","skeletal muscle":"731.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"236.4","Hepatocytes":"1012.8","Late spermatids":"534.6","monocytes":"273.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"neutrophil":"475.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"475.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Lung - Neutrophil_2","Prostate - Prostate glandular cells","Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011316","HPA011317","HPA011964"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA011316":"AB_1844536","HPA011317":null,"HPA011964":"AB_1844537"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"}},{"Gene":"ACSL3","Gene synonym":["ACS3","FACL3","PRO2194"],"Ensembl":"ENSG00000123983","Gene description":"Acyl-CoA synthetase long chain family member 3","Uniprot":["O95573"],"Chromosome":"2","Position":"222860942-222944639","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Ligase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"172.1"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011315","HPA071021"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Nucleoli rim","Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"37000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Lipid droplets"],"Antibody RRID":{"HPA011315":"AB_1848344","HPA071021":"AB_2686335"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.75e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.78e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"}},{"Gene":"ACSL4","Gene synonym":["ACS4","FACL4","LACS4","MRX63","MRX68"],"Ensembl":"ENSG00000068366","Gene description":"Acyl-CoA synthetase long chain family member 4","Uniprot":["O60488"],"Chromosome":"X","Position":"109624244-109733403","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Ligase"],"Disease involvement":["Alport syndrome","Deafness","Disease variant","Elliptocytosis","Hereditary hemolytic anemia","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"222.1","granulocytes":"253.9","monocytes":"192.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000286","HPA005552"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA000286":"AB_2665966","HPA005552":"AB_1078774"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.73e-4"}},{"Gene":"ACSL5","Gene synonym":["ACS2","ACS5","FACL5"],"Ensembl":"ENSG00000197142","Gene description":"Acyl-CoA synthetase long chain family member 5","Uniprot":["Q9ULC5"],"Chromosome":"10","Position":"112374018-112428380","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"217.8","intestine":"418.0","liver":"165.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"125.3","Endometrial ciliated cells":"136.1","Glandular and luminal cells":"300.7","Proximal enterocytes":"467.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"87.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"89.6","colorectal cancer":"87.7"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007162","CAB035986","CAB062546"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB035986":"AB_941506","CAB062546":"AB_2665614","HPA007162":"AB_2667761"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.13e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"}},{"Gene":"ACSL6","Gene synonym":["ACS2","FACL6","KIAA0837","LACS2","LACS5"],"Ensembl":"ENSG00000164398","Gene description":"Acyl-CoA synthetase long chain family member 6","Uniprot":["Q9UKU0"],"Chromosome":"5","Position":"131949973-132012243","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"22.6","brain":"32.0","retina":"45.8","testis":"20.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"222.1","Basal prostatic cells":"74.8","Cone photoreceptor cells":"163.7","Excitatory neurons":"69.6","Inhibitory neurons":"108.2","Rod photoreceptor cells":"142.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"colorectal cancer":"1.8","glioma":"1.9","liver cancer":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory CD8 T-cell":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"1.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Breast - T-cells","Heart muscle - Cardiomyocytes","Kidney - Ascending Loop of Henle cells","Liver - Hepatocytes","Testis - Early spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040470"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040470":"AB_10794033"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"}},{"Gene":"ACSS2","Gene synonym":["ACAS2","AceCS","ACS","ACSA","dJ1161H23.1"],"Ensembl":"ENSG00000131069","Gene description":"Acyl-CoA synthetase short chain family member 2","Uniprot":["Q9NR19"],"Chromosome":"20","Position":"34872146-34927962","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"117.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"125.5","Hepatocytes":"109.2","Intestinal goblet cells":"121.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"34.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"22.6","granulocytes":"34.3","monocytes":"21.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Kidney - Proximal tubular cells","Liver - Hepatocytes","Lung - Alveolar cells type 2","Skin - Sebaceous gland cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004141"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004141":"AB_1078094"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.04e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"}},{"Gene":"ACTL6A","Gene synonym":["Actl6","Arp4","BAF53A","INO80K"],"Ensembl":"ENSG00000136518","Gene description":"Actin like 6A","Uniprot":["O96019"],"Chromosome":"3","Position":"179562886-179588407","Protein class":["Disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA recombination","DNA repair","Growth regulation","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"226.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012188","HPA018671","HPA063149"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB012188":"AB_304125","HPA018671":"AB_2669914","HPA063149":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.89e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.44e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.80e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"}},{"Gene":"ACTN1","Gene synonym":[],"Ensembl":"ENSG00000072110","Gene description":"Actinin alpha 1","Uniprot":["P12814"],"Chromosome":"14","Position":"68874128-68979440","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"smooth muscle":"524.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"320.1","Extravillous trophoblasts":"372.4","Pancreatic endocrine cells":"340.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"364.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Lung - Smooth muscle cells","Prostate - Smooth muscle cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004303","HPA006035"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments","Focal adhesion sites","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Actin filaments","Focal adhesion sites"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"CAB004303":"AB_626633","HPA006035":"AB_1078095"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.63e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.08e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.00e-4"}},{"Gene":"ACTR3","Gene synonym":["ARP3"],"Ensembl":"ENSG00000115091","Gene description":"Actin related protein 3","Uniprot":["P61158"],"Chromosome":"2","Position":"113890063-113962596","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005085","HPA047016","HPA051683"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"25000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB005085":"AB_2289106","HPA047016":"AB_2679903","HPA051683":"AB_2681573"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.52e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.76e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.81e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-1"}},{"Gene":"ACTR3B","Gene synonym":["ARP11","ARP3beta"],"Ensembl":"ENSG00000133627","Gene description":"Actin related protein 3B","Uniprot":["Q9P1U1"],"Chromosome":"7","Position":"152759749-152855378","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"57.6","Excitatory neurons":"63.1","Peritubular cells":"54.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047016","HPA051683"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047016":"AB_2679903","HPA051683":"AB_2681573"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.53e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"}},{"Gene":"ACTR6","Gene synonym":["ARP6","FLJ13433"],"Ensembl":"ENSG00000075089","Gene description":"Actin related protein 6","Uniprot":["Q9GZN1"],"Chromosome":"12","Position":"100199122-100241865","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"136.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038587","HPA038588"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038587":"AB_10670781","HPA038588":"AB_10672719"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.70e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"}},{"Gene":"ACVR1","Gene synonym":["ACVR1A","ACVRLK2","ALK2","SKR1"],"Ensembl":"ENSG00000115170","Gene description":"Activin A receptor type 1","Uniprot":["Q04771"],"Chromosome":"2","Position":"157736444-157876330","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"104.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"6.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007505","HPA046514"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA007505":"AB_1844752","HPA046514":"AB_2732526"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.17e-4"}},{"Gene":"ACVR1B","Gene synonym":["ActRIB","ACVRLK4","ALK4","SKR2"],"Ensembl":"ENSG00000135503","Gene description":"Activin A receptor type 1B","Uniprot":["P36896"],"Chromosome":"12","Position":"51951699-51997078","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"3.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026126","HPA063761"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB026126":null,"HPA063761":"AB_2685115"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"}},{"Gene":"ACVR1C","Gene synonym":["ACVRLK7","ALK7"],"Ensembl":"ENSG00000123612","Gene description":"Activin A receptor type 1C","Uniprot":["Q8NER5"],"Chromosome":"2","Position":"157526767-157628864","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"31.3","brain":"10.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"25.8","Leydig cells":"34.7","Oligodendrocytes":"52.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"6.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"29.7"},"Antibody":["HPA007982","HPA011933"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007982":"AB_1078134","HPA011933":"AB_1844754"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"}},{"Gene":"ACVR2A","Gene synonym":["ACTRII","ACVR2"],"Ensembl":"ENSG00000121989","Gene description":"Activin A receptor type 2A","Uniprot":["P27037"],"Chromosome":"2","Position":"147844517-147930826","Protein class":["Cancer-related genes","Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"61.5","Inhibitory neurons":"61.9","Oligodendrocyte precursor cells":"81.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046997"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046997":"AB_10970077"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"}},{"Gene":"ACVR2B","Gene synonym":["ActR-IIB"],"Ensembl":"ENSG00000114739","Gene description":"Activin A receptor type 2B","Uniprot":["Q13705"],"Chromosome":"3","Position":"38453890-38493142","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Heterotaxy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"5.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"14.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025115","HPA040384"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025115":null,"HPA040384":"AB_2732484"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-1"}},{"Gene":"ACVRL1","Gene synonym":["ACVRLK1","ALK1","HHT","HHT2","ORW2"],"Ensembl":"ENSG00000139567","Gene description":"Activin A receptor like type 1","Uniprot":["P37023"],"Chromosome":"12","Position":"51906908-51923361","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis"],"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"96.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"100.1","Distal enterocytes":"126.4","Endothelial cells":"100.7","Extravillous trophoblasts":"44.3","Fibroblasts":"57.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"classical monocyte":"1.5","myeloid DC":"2.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"2.1","monocytes":"1.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"7.9"},"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007041"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007041":"AB_1078097"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"}},{"Gene":"ADAM10","Gene synonym":["CD156C","HsT18717","kuz","MADM"],"Ensembl":"ENSG00000137845","Gene description":"ADAM metallopeptidase domain 10","Uniprot":["O14672"],"Chromosome":"15","Position":"58588809-58749791","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Notch signaling pathway"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Alzheimer disease","Amyloidosis","Cancer-related genes","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"356.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001709","HPA050670"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"690000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB001709":null,"HPA050670":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.46e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"}},{"Gene":"ADAM11","Gene synonym":["MDC"],"Ensembl":"ENSG00000073670","Gene description":"ADAM metallopeptidase domain 11","Uniprot":["O75078"],"Chromosome":"17","Position":"44758988-44781846","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"36.6","heart muscle":"11.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"10.4","Cardiomyocytes":"11.8","Excitatory neurons":"46.4","Horizontal cells":"34.6","Inhibitory neurons":"22.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"6.4"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074550"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074550":"AB_2732259"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"}},{"Gene":"ADAM12","Gene synonym":["MCMPMltna","MLTN"],"Ensembl":"ENSG00000148848","Gene description":"ADAM metallopeptidase domain 12","Uniprot":["O43184"],"Chromosome":"10","Position":"126012381-126388455","Protein class":["Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"placenta":"166.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"482.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"MAIT T-cell":"6.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"62","RNA blood lineage specific nTPM":{"T-cells":"6.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"49.4"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030866","HPA030867","HPA030868"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted in female reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA030866":"AB_2673636","HPA030867":"AB_10602428","HPA030868":"AB_2673638"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.39e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-3"}},{"Gene":"ADAM15","Gene synonym":["MDC15"],"Ensembl":"ENSG00000143537","Gene description":"ADAM metallopeptidase domain 15","Uniprot":["Q13444"],"Chromosome":"1","Position":"155050566-155062775","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Cell adhesion","Collagen degradation"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"164.0","Endothelial cells":"140.5","Extravillous trophoblasts":"192.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"39.1","intermediate monocyte":"26.5","myeloid DC":"64.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"64.0","monocytes":"39.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Heart muscle - Endothelial cells","Pancreas - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011633","HPA072878"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"640000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA011633":"AB_1844574","HPA072878":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.83e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.64e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"}},{"Gene":"ADAM17","Gene synonym":["CD156B","cSVP","TACE"],"Ensembl":"ENSG00000151694","Gene description":"ADAM metallopeptidase domain 17","Uniprot":["P78536"],"Chromosome":"2","Position":"9488486-9556732","Protein class":["CD markers","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Notch signaling pathway"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010738","HPA051575"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"300000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA010738":"AB_1078100","HPA051575":"AB_2681539"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.23e-5"}},{"Gene":"ADAM18","Gene synonym":["ADAM27","tMDCIII"],"Ensembl":"ENSG00000168619","Gene description":"ADAM metallopeptidase domain 18","Uniprot":["Q9Y3Q7"],"Chromosome":"8","Position":"39584489-39730065","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"74","RNA tissue specific nTPM":{"testis":"9.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"79.6","Spermatocytes":"117.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-4"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ADAM19","Gene synonym":["MLTNB"],"Ensembl":"ENSG00000135074","Gene description":"ADAM metallopeptidase domain 19","Uniprot":["Q9H013"],"Chromosome":"5","Position":"157395534-157575775","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"45.8","Cone photoreceptor cells":"51.7","dendritic cells":"64.4","Extravillous trophoblasts":"96.4","Langerhans cells":"52.8","Plasma cells":"61.0","Rod photoreceptor cells":"50.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"128.3","eosinophil":"139.9","memory B-cell":"50.8","naive B-cell":"53.5","neutrophil":"70.5","plasmacytoid DC":"66.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"53.5","dendritic cells":"66.8","granulocytes":"139.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055537"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA055537":"AB_2797253"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.90e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"}},{"Gene":"ADAM2","Gene synonym":["CT15","FTNB","PH-30b","PH30"],"Ensembl":"ENSG00000104755","Gene description":"ADAM metallopeptidase domain 2","Uniprot":["Q99965"],"Chromosome":"8","Position":"39743735-39838289","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"129","RNA tissue specific nTPM":{"testis":"38.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"37.6","Spermatocytes":"76.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"prostate cancer":"1.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022390","HPA024621","HPA026581"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022390":null,"HPA024621":"AB_1844576","HPA026581":"AB_1844577"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"}},{"Gene":"ADAM20","Gene synonym":[],"Ensembl":"ENSG00000134007","Gene description":"ADAM metallopeptidase domain 20","Uniprot":["O43506"],"Chromosome":"14","Position":"70522358-70535015","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"1.6","testis":"5.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"29.1","Early spermatids":"60.2","Excitatory neurons":"44.8","Inhibitory neurons":"36.5","Oligodendrocyte precursor cells":"22.1","Oligodendrocytes":"22.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059377"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059377":"AB_2683997"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"}},{"Gene":"ADAM21","Gene synonym":["ADAM31"],"Ensembl":"ENSG00000139985","Gene description":"ADAM metallopeptidase domain 21","Uniprot":["Q9UKJ8"],"Chromosome":"14","Position":"70417107-70460427","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"testis":"8.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"51","RNA single cell type specific nTPM":{"Early spermatids":"64.3","Late spermatids":"144.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059016"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059016":"AB_2683882"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"}},{"Gene":"ADAM22","Gene synonym":["MDC2"],"Ensembl":"ENSG00000008277","Gene description":"ADAM metallopeptidase domain 22","Uniprot":["Q9P0K1"],"Chromosome":"7","Position":"87934143-88202889","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"77.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"282.6","Inhibitory neurons":"298.1","Oligodendrocyte precursor cells":"176.2","Oligodendrocytes":"118.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"4.0"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"77.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"31.7"},"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050325","CAB079064"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB079064":null,"HPA050325":"AB_2681087"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"}},{"Gene":"ADAM23","Gene synonym":["MDC3"],"Ensembl":"ENSG00000114948","Gene description":"ADAM metallopeptidase domain 23","Uniprot":["O75077"],"Chromosome":"2","Position":"206443532-206621127","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"45.7","parathyroid gland":"82.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"82.1","Excitatory neurons":"404.1","Inhibitory neurons":"231.6","Late spermatids":"60.8","Oligodendrocyte precursor cells":"121.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"memory CD4 T-cell":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"T-cells":"2.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"43.7"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Cardiomyocytes","Lung - Fibroblast_2","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033276"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"890000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033276":"AB_2305247"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"}},{"Gene":"ADAM28","Gene synonym":["ADAM23","eMDCII","MDC-Lm","MDC-Ls"],"Ensembl":"ENSG00000042980","Gene description":"ADAM metallopeptidase domain 28","Uniprot":["Q9UKQ2"],"Chromosome":"8","Position":"24294069-24359014","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"epididymis":"357.5","stomach 1":"110.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"226.9","Gastric mucus-secreting cells":"133.0","Ionocytes":"77.4","Microglial cells":"227.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"9.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"71.6","naive B-cell":"87.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"13.5"},"RNA tissue cell type enrichment":["Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074034"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Mitochondria"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA074034":"AB_2686654"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"}},{"Gene":"ADAM29","Gene synonym":["CT73","svph1"],"Ensembl":"ENSG00000168594","Gene description":"ADAM metallopeptidase domain 29","Uniprot":["Q9UKF5"],"Chromosome":"4","Position":"174829668-174978180","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"62","RNA tissue specific nTPM":{"testis":"41.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Early spermatids":"402.3","Late spermatids":"308.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ADAM30","Gene synonym":["svph4"],"Ensembl":"ENSG00000134249","Gene description":"ADAM metallopeptidase domain 30","Uniprot":["Q9UKF2"],"Chromosome":"1","Position":"119893533-119896515","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"259","RNA tissue specific nTPM":{"testis":"25.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"100.1","Spermatocytes":"48.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026080"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026080":"AB_1844581"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ADAM32","Gene synonym":[],"Ensembl":"ENSG00000197140","Gene description":"ADAM metallopeptidase domain 32","Uniprot":["Q8TC27"],"Chromosome":"8","Position":"39106990-39284917","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"testis":"27.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"222.9","Excitatory neurons":"36.8","Inhibitory neurons":"29.2","Late spermatids":"56.7","Spermatocytes":"81.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044156","HPA062151"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA044156":"AB_10796798","HPA062151":"AB_2684699"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"}},{"Gene":"ADAM33","Gene synonym":["C20orf153","dJ964F7.1","DKFZp434K0521"],"Ensembl":"ENSG00000149451","Gene description":"ADAM metallopeptidase domain 33","Uniprot":["Q9BZ11"],"Chromosome":"20","Position":"3667965-3682246","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Asthma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"280.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"34.8","Fibroblasts":"37.6","Leydig cells":"22.4","Microglial cells":"18.2","Smooth muscle cells":"20.4","Thymic epithelial cells":"14.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"testis cancer":"16.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Breast - Fibroblasts","Liver - Hepatic stellate cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"1.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067152","HPA071758"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA067152":"AB_2685791","HPA071758":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"}},{"Gene":"ADAM7","Gene synonym":["EAPI","GP-83"],"Ensembl":"ENSG00000069206","Gene description":"ADAM metallopeptidase domain 7","Uniprot":["Q9H2U9"],"Chromosome":"8","Position":"24440930-24526970","Protein class":["Disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"237","RNA tissue specific nTPM":{"epididymis":"3726.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"118.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"16","RNA cancer specific FPKM":{"prostate cancer":"1.0","renal cancer":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"prostate cancer":"1.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008879"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008879":"AB_10601789"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-4"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ADAM8","Gene synonym":["CD156","CD156A","MS2"],"Ensembl":"ENSG00000151651","Gene description":"ADAM metallopeptidase domain 8","Uniprot":["P78325"],"Chromosome":"10","Position":"133262420-133276868","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"68.6","lymphoid tissue":"48.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"106.5","Langerhans cells":"165.1","NK-cells":"69.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"21.2"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"107.4","eosinophil":"259.0","neutrophil":"139.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"259.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"58.7"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Breast - T-cells","Heart muscle - Neutrophils","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064637"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064637":"AB_2685306"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.99e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"}},{"Gene":"ADAM9","Gene synonym":["CORD9","KIAA0021","MCMP","MDC9","Mltng"],"Ensembl":"ENSG00000168615","Gene description":"ADAM metallopeptidase domain 9","Uniprot":["Q13443"],"Chromosome":"8","Position":"38996754-39105445","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes","Cone-rod dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"174.6","Mucus glandular cells":"174.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"4.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004000"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"740000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA004000":"AB_1844584"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.25e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.21e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.99e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"}},{"Gene":"ADAMTS18","Gene synonym":["ADAMTS21"],"Ensembl":"ENSG00000140873","Gene description":"ADAM metallopeptidase with thrombospondin type 1 motif 18","Uniprot":["Q8TE60"],"Chromosome":"16","Position":"77247813-77435034","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"11.0","placenta":"20.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"36.3","Granulosa cells":"14.5","Muller glia cells":"10.5","Oligodendrocytes":"15.9","Rod photoreceptor cells":"8.5","Serous glandular cells":"6.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"testis cancer":"10.6"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebellum":"3.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044326"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Midbody","Mitotic spindle"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Midbody","Mitotic spindle"],"Subcellular additional location":null,"Antibody RRID":{"HPA044326":"AB_10961006"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-4"}},{"Gene":"ADAMTS4","Gene synonym":["ADAMTS-2","ADMP-1","KIAA0688"],"Ensembl":"ENSG00000158859","Gene description":"ADAM metallopeptidase with thrombospondin type 1 motif 4","Uniprot":["O75173"],"Chromosome":"1","Position":"161184302-161199054","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"116.8","ovary":"95.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"77.6","Endothelial cells":"92.9","Fibroblasts":"52.1","Oligodendrocytes":"52.9","Smooth muscle cells":"188.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"plasmacytoid DC":"4.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"4.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"8.4","skin cancer":"5.3"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Neutrophils"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025876","HPA051296","HPA068374"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"11000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"CAB025876":null,"HPA051296":"AB_2681426","HPA068374":"AB_2685978"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.00e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.27e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"}},{"Gene":"ADAMTSL2","Gene synonym":["KIAA0605"],"Ensembl":"ENSG00000197859","Gene description":"ADAMTS like 2","Uniprot":["Q86TH1"],"Chromosome":"9","Position":"133532164-133575519","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"73.2","liver":"35.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"9.3","Fibroblasts":"9.4","Microglial cells":"11.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"4.3"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Kidney - Fibroblasts","Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045634","HPA053812"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA045634":"AB_2679399","HPA053812":"AB_2682271"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.70e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"}},{"Gene":"ADAMTSL4","Gene synonym":["DKFZP434K1772","TSRC1"],"Ensembl":"ENSG00000143382","Gene description":"ADAMTS like 4","Uniprot":["Q6UY14"],"Chromosome":"1","Position":"150549369-150560937","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"145.4","Endometrial stromal cells":"37.2","Extravillous trophoblasts":"45.0","Skeletal myocytes":"51.5","Syncytiotrophoblasts":"94.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"11.1"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"38.4"},"RNA tissue cell type enrichment":["Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006279"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA006279":"AB_1078102"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.86e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.43e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.35e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-3"}},{"Gene":"ADAP1","Gene synonym":["CENTA1","GCS1L"],"Ensembl":"ENSG00000105963","Gene description":"ArfGAP with dual PH domains 1","Uniprot":["O75689"],"Chromosome":"7","Position":"897900-955407","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"85.9","intestine":"43.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"76.4","Intestinal goblet cells":"43.1","Oligodendrocytes":"41.2","Paneth cells":"50.2","Proximal enterocytes":"46.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"15.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"109.6","Gastric cancer":"101.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007033","HPA012049"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007033":"AB_1846529","HPA012049":"AB_1846527"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.25e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.13e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.13e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"}},{"Gene":"ADCK2","Gene synonym":["MGC20727"],"Ensembl":"ENSG00000133597","Gene description":"AarF domain containing kinase 2","Uniprot":["Q7Z695"],"Chromosome":"7","Position":"140672945-140696261","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"95.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036036"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036036":"AB_10672078"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"}},{"Gene":"ADCK5","Gene synonym":["FLJ35454"],"Ensembl":"ENSG00000173137","Gene description":"AarF domain containing kinase 5","Uniprot":["Q3MIX3"],"Chromosome":"8","Position":"144373101-144393242","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"56.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025692","HPA028679"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA025692":"AB_10599486","HPA028679":"AB_10600226"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"}},{"Gene":"ADCY1","Gene synonym":["AC1","DFNB44"],"Ensembl":"ENSG00000164742","Gene description":"Adenylate cyclase 1","Uniprot":["Q08828"],"Chromosome":"7","Position":"45574140-45723116","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms","cAMP biosynthesis"],"Molecular function":["Calmodulin-binding","Lyase"],"Disease involvement":["Cancer-related genes","Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"33.7","liver":"19.2","retina":"53.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"267.1","Excitatory neurons":"145.1","Horizontal cells":"100.6","Inhibitory neurons":"115.6","Rod photoreceptor cells":"208.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"23.4"},"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018364","HPA068274"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB018364":"AB_2223098","HPA068274":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"}},{"Gene":"ADCY10","Gene synonym":["HCA2","RP1-313L4.2","SAC","SACI","Sacy"],"Ensembl":"ENSG00000143199","Gene description":"Adenylate cyclase 10","Uniprot":["Q96PN6"],"Chromosome":"1","Position":"167809386-167914215","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"6.1","testis":"17.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"85.1","Late spermatids":"88.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015243","HPA017749"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015243":"AB_1856540","HPA017749":"AB_1856541"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"}},{"Gene":"ADCY2","Gene synonym":["AC2","HBAC2","KIAA1060"],"Ensembl":"ENSG00000078295","Gene description":"Adenylate cyclase 2","Uniprot":["Q08462"],"Chromosome":"5","Position":"7396138-7830081","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"50.8","skeletal muscle":"68.3","tongue":"30.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"626.9","Excitatory neurons":"400.0","Inhibitory neurons":"413.6","Oligodendrocyte precursor cells":"173.8","Skeletal myocytes":"110.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"4.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"4.0","testis cancer":"3.8"},"RNA tissue cell type enrichment":["Breast - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB031482","HPA038015","HPA038483"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB031482":"AB_630838","HPA038015":"AB_10673653","HPA038483":"AB_10675799"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"}},{"Gene":"ADCY3","Gene synonym":["AC3"],"Ensembl":"ENSG00000138031","Gene description":"Adenylate cyclase 3","Uniprot":["O60266"],"Chromosome":"2","Position":"24819169-24920237","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis","Olfaction","Sensory transduction"],"Molecular function":["Calmodulin-binding","Lyase"],"Disease involvement":["Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"61.6","Sertoli cells":"47.0","Smooth muscle cells":"64.0","Theca cells":"77.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010223"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010223":"AB_630839"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-3"}},{"Gene":"ADCY4","Gene synonym":["AC4"],"Ensembl":"ENSG00000129467","Gene description":"Adenylate cyclase 4","Uniprot":["Q8NFM4"],"Chromosome":"14","Position":"24318349-24335093","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Adipocytes":"83.5","Endothelial cells":"74.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"2.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"2.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005070","HPA048344"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB005070":"AB_2273639","HPA048344":"AB_2680366"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.20e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"}},{"Gene":"ADCY5","Gene synonym":["AC5"],"Ensembl":"ENSG00000173175","Gene description":"Adenylate cyclase 5","Uniprot":["O95622"],"Chromosome":"3","Position":"123282296-123449090","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"97.7","heart muscle":"105.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"94.1","Excitatory neurons":"33.5","Horizontal cells":"38.5","Inhibitory neurons":"42.9","Oligodendrocytes":"84.7","Paneth cells":"55.2","Peritubular cells":"71.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"11.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Liver - Hepatic stellate cells","Lung - Smooth muscle cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"388.0"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"155.9"},"Antibody":["HPA017730","HPA077682"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA017730":"AB_1844595","HPA077682":"AB_2686851"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.46e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-4"}},{"Gene":"ADCY6","Gene synonym":["AC6"],"Ensembl":"ENSG00000174233","Gene description":"Adenylate cyclase 6","Uniprot":["O43306"],"Chromosome":"12","Position":"48766194-48789089","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"41.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018365"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB018365":"AB_2257941"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.23e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"}},{"Gene":"ADCY7","Gene synonym":["AC7","KIAA0037"],"Ensembl":"ENSG00000121281","Gene description":"Adenylate cyclase 7","Uniprot":["P51828"],"Chromosome":"16","Position":"50246137-50318135","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"42.5","Kupffer cells":"68.1","Langerhans cells":"56.2","Macrophages":"49.6","Microglial cells":"51.1","monocytes":"66.0","NK-cells":"60.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041218","HPA048241"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA041218":"AB_2677365","HPA048241":"AB_2680326"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.31e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-4"}},{"Gene":"ADCY8","Gene synonym":["AC8","ADCY3","HBAC1"],"Ensembl":"ENSG00000155897","Gene description":"Adenylate cyclase 8","Uniprot":["P40145"],"Chromosome":"8","Position":"130780301-131040909","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"29.4","epididymis":"22.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"147.1","Inhibitory neurons":"245.5","Oligodendrocyte precursor cells":"132.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"6.0","ovarian cancer":"1.8","thyroid cancer":"1.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"2.6","Rhabdoid":"1.0"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Eccrine sweat gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018652","HPA024291"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB018652":"AB_633654","HPA024291":"AB_1844597"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"ADCY9","Gene synonym":["AC9"],"Ensembl":"ENSG00000162104","Gene description":"Adenylate cyclase 9","Uniprot":["O60503"],"Chromosome":"16","Position":"3953387-4116442","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"45.4","skeletal muscle":"52.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"93.9","Inhibitory neurons":"71.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041328","HPA044225"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA041328":"AB_2677414","HPA044225":"AB_2678863"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.55e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.24e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"}},{"Gene":"ADCYAP1R1","Gene synonym":["PAC1","PAC1R","PACAPR"],"Ensembl":"ENSG00000078549","Gene description":"ADCYAP receptor type I","Uniprot":["P41586"],"Chromosome":"7","Position":"31052308-31111479","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"148.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"55.4","Inhibitory neurons":"44.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"45.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"Neuroblastoma":"33.4"},"RNA tissue cell type enrichment":["Pancreas - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030739","HPA049877"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA030739":"AB_2732461","HPA049877":"AB_2680928"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.78e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-4"}},{"Gene":"ADGRA1","Gene synonym":["GPR123","KIAA1828"],"Ensembl":"ENSG00000197177","Gene description":"Adhesion G protein-coupled receptor A1","Uniprot":["Q86SQ6"],"Chromosome":"10","Position":"133070929-133131675","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"38.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Excitatory neurons":"24.9","Horizontal cells":"24.4","Inhibitory neurons":"24.1","Oligodendrocyte precursor cells":"27.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"glioma":"3.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"6.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Lung - Respiratory ciliated cells","Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042773"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042773":"AB_10794764"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ADGRA2","Gene synonym":["DKFZp434C211","DKFZp434J0911","FLJ14390","GPR124","KIAA1531","TEM5"],"Ensembl":"ENSG00000020181","Gene description":"Adhesion G protein-coupled receptor A2","Uniprot":["Q96PE1"],"Chromosome":"8","Position":"37784191-37844896","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Wnt signaling pathway"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"29.8","Endometrial stromal cells":"45.7","Endothelial cells":"22.7","Fibroblasts":"38.1","Leydig cells":"53.3","Microglial cells":"23.7","Muller glia cells":"26.7","Peritubular cells":"41.4","Smooth muscle cells":"42.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"31.6"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Liver - Hepatic stellate cells","Skeletal muscle - Fibroblasts","Skin - Fibroblast_1","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008984","HPA012393"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA008984":null,"HPA012393":"AB_1849256"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.18e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"}},{"Gene":"ADGRA3","Gene synonym":["FLJ38547","GPR125","PGR21"],"Ensembl":"ENSG00000152990","Gene description":"Adhesion G protein-coupled receptor A3","Uniprot":["Q8IWK6"],"Chromosome":"4","Position":"22345071-22516066","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"58.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"214.8","Hepatocytes":"92.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008904"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008904":"AB_1849258"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"}},{"Gene":"ADGRB1","Gene synonym":["BAI1"],"Ensembl":"ENSG00000181790","Gene description":"Adhesion G protein-coupled receptor B1","Uniprot":["O14514"],"Chromosome":"8","Position":"142449430-142545009","Protein class":["Cancer-related genes","G-protein coupled receptors","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity","Innate immunity","Myogenesis","Neurogenesis","Phagocytosis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"37.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"56.9","Bipolar cells":"24.3","Excitatory neurons":"46.8","Horizontal cells":"47.4","Inhibitory neurons":"37.1","Oligodendrocyte precursor cells":"67.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"11.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"}},{"Gene":"ADGRB2","Gene synonym":["BAI2"],"Ensembl":"ENSG00000121753","Gene description":"Adhesion G protein-coupled receptor B2","Uniprot":["O60241"],"Chromosome":"1","Position":"31727117-31764893","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"61.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"20.2","Excitatory neurons":"55.0","Horizontal cells":"28.2","Inhibitory neurons":"13.5","Oligodendrocyte precursor cells":"19.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"20.5"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"61.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069175"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"32000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA069175":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.46e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.02e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"}},{"Gene":"ADGRB3","Gene synonym":["BAI3","KIAA0550"],"Ensembl":"ENSG00000135298","Gene description":"Adhesion G protein-coupled receptor B3","Uniprot":["O60242"],"Chromosome":"6","Position":"68635282-69389506","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"49.6","pituitary gland":"23.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Astrocytes":"1739.4","Excitatory neurons":"3790.8","Inhibitory neurons":"2675.1","Oligodendrocyte precursor cells":"1950.0","Oligodendrocytes":"1142.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"glioma":"3.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"12.0"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Liver - Hepatic stellate cells","Lung - Fibroblast_1","Prostate - Fibroblasts","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8600","Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-3"}},{"Gene":"ADGRD1","Gene synonym":["DKFZp434B1272","GPR133","PGR25"],"Ensembl":"ENSG00000111452","Gene description":"Adhesion G protein-coupled receptor D1","Uniprot":["Q6QNK2"],"Chromosome":"12","Position":"130953907-131141469","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"62.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"26.5","Cardiomyocytes":"34.3","Endometrial stromal cells":"46.7","Fibroblasts":"30.1","Late spermatids":"22.6","Microglial cells":"24.6","Sertoli cells":"33.2","Thymic epithelial cells":"76.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"2.0","intermediate monocyte":"2.3","myeloid DC":"1.1","non-classical monocyte":"1.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"1.1","monocytes":"2.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"5.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042395","HPA076279"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear speckles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Nuclear speckles"],"Antibody RRID":{"HPA042395":"AB_10796906","HPA076279":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"}},{"Gene":"ADGRD2","Gene synonym":["GPR144","PGR24"],"Ensembl":"ENSG00000180264","Gene description":"Adhesion G protein-coupled receptor D2","Uniprot":["Q7Z7M1"],"Chromosome":"9","Position":"124451425-124478589","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.3","pituitary gland":"1.6","seminal vesicle":"1.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"27.0","Late spermatids":"86.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"spinal cord":"1.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"1.1"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-6"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"}},{"Gene":"ADGRE1","Gene synonym":["EMR1","TM7LN3"],"Ensembl":"ENSG00000174837","Gene description":"Adhesion G protein-coupled receptor E1","Uniprot":["Q14246"],"Chromosome":"19","Position":"6887566-6940459","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"6.8","lymphoid tissue":"14.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"24.9","Macrophages":"12.4","monocytes":"65.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"166.4","eosinophil":"324.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"granulocytes":"324.9","monocytes":"105.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052809"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052809":"AB_2681959"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"}},{"Gene":"ADGRE2","Gene synonym":["CD312","EMR2"],"Ensembl":"ENSG00000127507","Gene description":"Adhesion G protein-coupled receptor E2","Uniprot":["Q9UHX3"],"Chromosome":"19","Position":"14732392-14778560","Protein class":["CD markers","Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cell adhesion","Inflammatory response"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"19.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"52.9","Hofbauer cells":"30.3","Kupffer cells":"68.8","Macrophages":"66.3","monocytes":"182.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"70.0","eosinophil":"74.7","intermediate monocyte":"46.9","neutrophil":"55.7","non-classical monocyte":"89.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"74.7","monocytes":"89.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"7.4"},"RNA tissue cell type enrichment":["Lung - Neutrophil_2"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055200"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA055200":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.35e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"}},{"Gene":"ADGRE3","Gene synonym":["EMR3"],"Ensembl":"ENSG00000131355","Gene description":"Adhesion G protein-coupled receptor E3","Uniprot":["Q9BY15"],"Chromosome":"19","Position":"14619117-14690027","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"3.1","lymphoid tissue":"6.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"2.6","Inhibitory neurons":"2.4","Macrophages":"6.3","Microglial cells":"3.6","monocytes":"13.3","Mucus glandular cells":"3.9","Oligodendrocytes":"2.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"281.6","eosinophil":"509.0","neutrophil":"489.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"509.0"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Stomach - Neutrophils"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015638"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015638":"AB_1848039"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"}},{"Gene":"ADGRE5","Gene synonym":["CD97","TM7LN1"],"Ensembl":"ENSG00000123146","Gene description":"Adhesion G protein-coupled receptor E5","Uniprot":["P48960"],"Chromosome":"19","Position":"14380501-14408725","Protein class":["CD markers","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"211.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"154.3","monocytes":"296.1","NK-cells":"305.8","T-cells":"182.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013707"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":10000000,"Blood concentration - Conc. blood MS [pg\/L]":"2400000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA013707":"AB_1846345"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.73e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.87e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"}},{"Gene":"ADGRF1","Gene synonym":["GPR110","hGPCR36","PGR19"],"Ensembl":"ENSG00000153292","Gene description":"Adhesion G protein-coupled receptor F1","Uniprot":["Q5T601"],"Chromosome":"6","Position":"46997708-47042350","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"esophagus":"17.5","kidney":"20.3","urinary bladder":"42.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"63.1","Club cells":"126.1","Collecting duct cells":"102.4","Glandular and luminal cells":"56.6","Ionocytes":"160.0","Respiratory ciliated cells":"125.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"66.3"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Pancreas - Ductal cells","Prostate - Urothelial cells","Stomach - Gastric mucous cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038438"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038438":"AB_10672645"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"}},{"Gene":"ADGRF2","Gene synonym":["GPR111","hGPCR35","PGR20"],"Ensembl":"ENSG00000164393","Gene description":"Adhesion G protein-coupled receptor F2","Uniprot":["Q8IZF7"],"Chromosome":"6","Position":"47656436-47697797","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"1.0","skin 1":"2.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"1.7","Excitatory neurons":"1.2","Respiratory ciliated cells":"1.0","Squamous epithelial cells":"1.6","Suprabasal keratinocytes":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035507"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035507":"AB_10601809"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-4"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"}},{"Gene":"ADGRF3","Gene synonym":["GPR113","hGPCR37","PGR23"],"Ensembl":"ENSG00000173567","Gene description":"Adhesion G protein-coupled receptor F3","Uniprot":["Q8IZF5"],"Chromosome":"2","Position":"26308173-26346817","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"11.1","Early spermatids":"6.0","Late spermatids":"30.3","Microglial cells":"5.5","Oligodendrocytes":"6.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044500"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA044500":"AB_10794290"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-5"}},{"Gene":"ADGRF4","Gene synonym":["FLJ38076","GPR115","PGR18"],"Ensembl":"ENSG00000153294","Gene description":"Adhesion G protein-coupled receptor F4","Uniprot":["Q8IZF3"],"Chromosome":"6","Position":"47685864-47722021","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"18.3","skin 1":"38.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"7.6","Extravillous trophoblasts":"17.4","Squamous epithelial cells":"16.6","Suprabasal keratinocytes":"32.4","Syncytiotrophoblasts":"9.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"8.2"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"hypothalamus":"1.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"16.3","head and neck cancer":"14.6"},"RNA tissue cell type enrichment":["Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007131","HPA007158"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA007131":"AB_2667756","HPA007158":"AB_1849254"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.52e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"}},{"Gene":"ADGRF5","Gene synonym":["DKFZp564O1923","GPR116","KIAA0758"],"Ensembl":"ENSG00000069122","Gene description":"Adhesion G protein-coupled receptor F5","Uniprot":["Q8IZF2"],"Chromosome":"6","Position":"46852522-46954943","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"104.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"399.4","Alveolar cells type 1":"207.5","Alveolar cells type 2":"288.4","Endothelial cells":"221.8","Microglial cells":"101.2","Smooth muscle cells":"86.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"5.7","lung cancer":"11.1","pancreatic cancer":"7.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Liver - Vascular Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.84e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"}},{"Gene":"ADGRG1","Gene synonym":["GPR56","TM7LN4","TM7XN1"],"Ensembl":"ENSG00000205336","Gene description":"Adhesion G protein-coupled receptor G1","Uniprot":["Q9Y653"],"Chromosome":"16","Position":"57610652-57665580","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","G-protein coupled receptor","Heparin-binding","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"216.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"222.4","Exocrine glandular cells":"161.1","NK-cells":"183.6","Syncytiotrophoblasts":"180.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"160.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"160.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Prostate - Prostate basal glandular cells","Skeletal muscle - Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046065"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"32000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046065":"AB_2679521"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.52e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"}},{"Gene":"ADGRG2","Gene synonym":["EDDM6","GPR64","HE6","TM7LN2"],"Ensembl":"ENSG00000173698","Gene description":"Adhesion G protein-coupled receptor G2","Uniprot":["Q8IZP9"],"Chromosome":"X","Position":"18989307-19122637","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"epididymis":"1227.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"10.7","Mucus glandular cells":"11.6","Oligodendrocyte precursor cells":"9.6","Prostatic glandular cells":"14.7","Serous glandular cells":"24.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"4.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"19.0"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001478","HPA050029"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"22000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001478":"AB_1078923","HPA050029":"AB_2680996"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"}},{"Gene":"ADGRG3","Gene synonym":["GPR97","Pb99","PGR26"],"Ensembl":"ENSG00000182885","Gene description":"Adhesion G protein-coupled receptor G3","Uniprot":["Q86Y34"],"Chromosome":"16","Position":"57668277-57689378","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"147.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endothelial cells":"4.1","Erythroid cells":"7.0","NK-cells":"2.9","Pancreatic endocrine cells":"3.4","Serous glandular cells":"2.9","T-cells":"3.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"10.6"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"142.3","neutrophil":"169.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"169.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"2.3","lymphoma":"1.9"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2","Skeletal muscle - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040469"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040469":"AB_10794032"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"}},{"Gene":"ADGRG4","Gene synonym":["GPR112","PGR17","RP1-299I16"],"Ensembl":"ENSG00000156920","Gene description":"Adhesion G protein-coupled receptor G4","Uniprot":["Q8IZF6"],"Chromosome":"X","Position":"136300963-136416890","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"1.0","intestine":"2.5","retina":"1.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Enteroendocrine cells":"62.8","Paneth cells":"45.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035324"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035324":"AB_10671512"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ADGRG5","Gene synonym":["GPR114","PGR27"],"Ensembl":"ENSG00000159618","Gene description":"Adhesion G protein-coupled receptor G5","Uniprot":["Q8IZF4"],"Chromosome":"16","Position":"57542643-57591681","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"3.9","lymphoid tissue":"10.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"6.2","dendritic cells":"30.5","Microglial cells":"10.9","NK-cells":"27.5","Plasma cells":"16.9","T-cells":"6.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"125.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"9.6","lymphoma":"6.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Heart muscle - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007133"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nuclear membrane","Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA007133":"AB_1849253"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.25e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-3"}},{"Gene":"ADGRG6","Gene synonym":["FLJ14937","GPR126"],"Ensembl":"ENSG00000112414","Gene description":"Adhesion G protein-coupled receptor G6","Uniprot":["Q86SQ4"],"Chromosome":"6","Position":"142301854-142446266","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"71.9","placenta":"47.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"111.8","Suprabasal keratinocytes":"40.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Enteric glia cells","Skin - Keratinocyte (other)","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017346"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017346":"AB_1849260"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.78e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"}},{"Gene":"ADGRG7","Gene synonym":["FLJ14454","GPR128"],"Ensembl":"ENSG00000144820","Gene description":"Adhesion G protein-coupled receptor G7","Uniprot":["Q96K78"],"Chromosome":"3","Position":"100609601-100695479","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"intestine":"42.9","liver":"24.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"22.7","Intestinal goblet cells":"9.6","Paneth cells":"20.4","Proximal enterocytes":"34.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"3.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"1.8","Brain cancer":"1.5"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056451"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA056451":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"}},{"Gene":"ADGRL1","Gene synonym":["CIRL1","KIAA0821","LEC2","LPHN1"],"Ensembl":"ENSG00000072071","Gene description":"Adhesion G protein-coupled receptor L1","Uniprot":["O94910"],"Chromosome":"19","Position":"14147743-14206187","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"48.0","Excitatory neurons":"52.0","Horizontal cells":"55.1","Inhibitory neurons":"45.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037974"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037974":"AB_10675623"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"}},{"Gene":"ADGRL2","Gene synonym":["KIAA0786","LEC1","LPHH1","LPHN2"],"Ensembl":"ENSG00000117114","Gene description":"Adhesion G protein-coupled receptor L2","Uniprot":["O95490"],"Chromosome":"1","Position":"81306147-81992436","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Excitatory neurons":"890.6","Inhibitory neurons":"631.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Endothelial cells","Prostate - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043447"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"700000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA043447":"AB_2678486"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.92e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.00e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"}},{"Gene":"ADGRL3","Gene synonym":["KIAA0768","LEC3","LPHN3"],"Ensembl":"ENSG00000150471","Gene description":"Adhesion G protein-coupled receptor L3","Uniprot":["Q9HAR2"],"Chromosome":"4","Position":"61201258-62078335","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"32.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Astrocytes":"565.9","Excitatory neurons":"686.2","Inhibitory neurons":"720.0","Oligodendrocyte precursor cells":"1245.7","Oligodendrocytes":"559.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"5.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"8.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Breast - Smooth muscle cells","Colon - Enteric glia cells","Liver - Hepatic stellate cells","Prostate - Fibroblasts","Skin - Outer root sheath cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015027","HPA015762","CAB022698"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022698":null,"HPA015027":"AB_1853243","HPA015762":"AB_1853245"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"}},{"Gene":"ADGRL4","Gene synonym":["ELTD1","ETL"],"Ensembl":"ENSG00000162618","Gene description":"Adhesion G protein-coupled receptor L4","Uniprot":["Q9HBW9"],"Chromosome":"1","Position":"78889764-79282124","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"73.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Adipocytes":"567.1","Endothelial cells":"303.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"12.4","thyroid cancer":"14.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Lung - Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Stomach - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025229"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3800000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA025229":"AB_10602493"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"}},{"Gene":"ADGRV1","Gene synonym":["DKFZp761P0710","FEB4","GPR98","KIAA0686","MASS1","USH2C","VLGR1"],"Ensembl":"ENSG00000164199","Gene description":"Adhesion G protein-coupled receptor V1","Uniprot":["Q8WXG9"],"Chromosome":"5","Position":"90529344-91164437","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Hydrolase","Receptor","Transducer"],"Disease involvement":["Deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"adrenal gland":"533.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Astrocytes":"2138.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"23.2"},"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Liver - Hepatocytes","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Skin - Eccrine sweat gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067503"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"HPA067503":"AB_2685856"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"}},{"Gene":"ADIG","Gene synonym":["MGC39724","RP5-1100H13.2","SMAF1"],"Ensembl":"ENSG00000182035","Gene description":"Adipogenin","Uniprot":["Q0VDE8"],"Chromosome":"20","Position":"38581195-38588463","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"testis":"53.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Late spermatids":"1756.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041124"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041124":"AB_10795534"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"ADIPOR1","Gene synonym":["ACDCR1","PAQR1"],"Ensembl":"ENSG00000159346","Gene description":"Adiponectin receptor 1","Uniprot":["Q96A54"],"Chromosome":"1","Position":"202940826-202958572","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.27e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"}},{"Gene":"ADIPOR2","Gene synonym":["ACDCR2","PAQR2"],"Ensembl":"ENSG00000006831","Gene description":"Adiponectin receptor 2","Uniprot":["Q86V24"],"Chromosome":"12","Position":"1688574-1788674","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"303.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043737"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043737":"AB_10964205"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"}},{"Gene":"ADM5","Gene synonym":["AM5","C19orf76"],"Ensembl":"ENSG00000224420","Gene description":"Adrenomedullin 5 (putative)","Uniprot":["C9JUS6"],"Chromosome":"19","Position":"49688664-49690575","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Adipocytes":"37.6","Endothelial cells":"41.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.74e-4"}},{"Gene":"ADNP","Gene synonym":["ADNP1","KIAA0784"],"Ensembl":"ENSG00000101126","Gene description":"Activity dependent neuroprotector homeobox","Uniprot":["Q9H2P0"],"Chromosome":"20","Position":"50888916-50931437","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006371"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA006371":"AB_1078105"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.65e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"}},{"Gene":"ADORA1","Gene synonym":["RDC7"],"Ensembl":"ENSG00000163485","Gene description":"Adenosine A1 receptor","Uniprot":["P30542"],"Chromosome":"1","Position":"203090654-203167405","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"54.8","testis":"21.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"12.2","Excitatory neurons":"17.8","Muller glia cells":"41.6","Oligodendrocyte precursor cells":"33.7","Oligodendrocytes":"29.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"24.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"51.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Heart muscle - Cardiomyocytes","Kidney - Podocytes","Skin - Eccrine sweat gland cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044383"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA044383":"AB_2678921"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-4"}},{"Gene":"ADORA2A","Gene synonym":["ADORA2","RDC8"],"Ensembl":"ENSG00000128271","Gene description":"Adenosine A2a receptor","Uniprot":["P29274"],"Chromosome":"22","Position":"24417879-24442357","Protein class":["Cancer-related genes","FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"40.6","brain":"101.4","lymphoid tissue":"54.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"6.2","Gastric mucus-secreting cells":"1.8","Plasma cells":"10.5","T-cells":"3.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"101.4"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"44.1","Myeloma":"41.0"},"RNA tissue cell type enrichment":["Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"basal ganglia":"399.8"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"50","RNA pig brain regional specific nTPM":{"basal ganglia":"142.2"},"Antibody":["CAB001943","HPA065566","HPA075997"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001943":null,"HPA065566":null,"HPA075997":"AB_2732298"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-3"}},{"Gene":"ADORA2B","Gene synonym":[],"Ensembl":"ENSG00000170425","Gene description":"Adenosine A2b receptor","Uniprot":["P29275"],"Chromosome":"17","Position":"15944917-15975746","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.7","urinary bladder":"14.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"46.7","Basal respiratory cells":"70.2","Basal squamous epithelial cells":"31.6","Langerhans cells":"31.8","Suprabasal keratinocytes":"36.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"14.9","myeloid DC":"9.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"97","RNA blood lineage specific nTPM":{"dendritic cells":"9.0","granulocytes":"14.9","monocytes":"5.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Urothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073747"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA073747":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"}},{"Gene":"ADORA3","Gene synonym":["AD026"],"Ensembl":"ENSG00000282608","Gene description":"Adenosine A3 receptor","Uniprot":["P0DMS8"],"Chromosome":"1","Position":"111499429-111503633","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"21.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"11.6","Hofbauer cells":"16.9","Kupffer cells":"13.7","Late spermatids":"18.0","Macrophages":"43.3"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"40","RNA blood cell specific nTPM":{"eosinophil":"601.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"40","RNA blood lineage specific nTPM":{"granulocytes":"601.6"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"1.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ADPRM","Gene synonym":["C17orf48","MDS006"],"Ensembl":"ENSG00000170222","Gene description":"ADP-ribose\/CDP-alcohol diphosphatase, manganese dependent","Uniprot":["Q3LIE5"],"Chromosome":"17","Position":"10697594-10711558","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"33.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023265","HPA023820"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023265":"AB_1845590","HPA023820":"AB_1845591"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.69e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.38e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"}},{"Gene":"ADRA1A","Gene synonym":["ADRA1C","ADRA1L1"],"Ensembl":"ENSG00000120907","Gene description":"Adrenoceptor alpha 1A","Uniprot":["P35348"],"Chromosome":"8","Position":"26748150-26867278","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"42.6","liver":"60.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"102.2","Early spermatids":"31.6","Inhibitory neurons":"120.0","Late spermatids":"38.8","Oligodendrocyte precursor cells":"109.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"0.9","prostate cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"4.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Prostate - Smooth muscle cells","Skin - Smooth muscle cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029678","HPA029679","HPA076693"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA029678":"AB_10602108","HPA029679":"AB_2673143","HPA076693":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"}},{"Gene":"ADRA1B","Gene synonym":[],"Ensembl":"ENSG00000170214","Gene description":"Adrenoceptor alpha 1B","Uniprot":["P35368"],"Chromosome":"5","Position":"159865080-159973012","Protein class":["Cancer-related genes","FDA approved drug targets","G-protein coupled receptors","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"36.9","liver":"11.4","lymphoid tissue":"11.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"40.9","Hepatocytes":"13.7","Horizontal cells":"8.3","Inhibitory neurons":"31.8","Thymic epithelial cells":"12.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"36.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074416"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA074416":"AB_2686688"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.00e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.98e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.67e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.40e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.19e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"}},{"Gene":"ADRA1D","Gene synonym":["ADRA1","ADRA1A","ADRA1R"],"Ensembl":"ENSG00000171873","Gene description":"Adrenoceptor alpha 1D","Uniprot":["P25100"],"Chromosome":"20","Position":"4220630-4249287","Protein class":["FDA approved drug targets","G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"9.6","cervix":"7.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"2.1","Inhibitory neurons":"2.3","Sertoli cells":"8.3","Smooth muscle cells":"6.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bone cancer":"28.7"},"RNA tissue cell type enrichment":["Adipose visceral - Smooth muscle cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038789"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038789":"AB_10673475"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-11"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-5"}},{"Gene":"ADRA2A","Gene synonym":["ADRA2","ADRA2R","ADRAR"],"Ensembl":"ENSG00000150594","Gene description":"Adrenoceptor alpha 2A","Uniprot":["P08913"],"Chromosome":"10","Position":"111077029-111080907","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"50.5","cervix":"46.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"67.4","Glandular and luminal cells":"31.9","Paneth cells":"130.0","Smooth muscle cells":"81.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"17.7"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"pons":"26.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"10.1"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.06e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"}},{"Gene":"ADRA2B","Gene synonym":["ADRA2L1","ADRA2RL1","ADRARL1"],"Ensembl":"ENSG00000274286","Gene description":"Adrenoceptor alpha 2B","Uniprot":["P18089"],"Chromosome":"2","Position":"96112876-96116571","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"6.8","Ionocytes":"13.1","Langerhans cells":"12.2","Sertoli cells":"8.3","Smooth muscle cells":"12.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"basal ganglia":"2.5","cerebellum":"1.0","thalamus":"3.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066029","HPA074948"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA066029":"AB_2685599","HPA074948":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"}},{"Gene":"ADRA2C","Gene synonym":["ADRA2L2","ADRA2RL2","ADRARL2"],"Ensembl":"ENSG00000184160","Gene description":"Adrenoceptor alpha 2C","Uniprot":["P18825"],"Chromosome":"4","Position":"3766348-3768526","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"84.9","endometrium 1":"57.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Endometrial stromal cells":"135.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"22.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"34.3"},"Antibody":["HPA057688"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057688":"AB_2683503"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"}},{"Gene":"ADRB1","Gene synonym":["ADRB1R"],"Ensembl":"ENSG00000043591","Gene description":"Adrenoceptor beta 1","Uniprot":["P08588"],"Chromosome":"10","Position":"114043866-114046904","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"23.7","lung":"13.1","placenta":"29.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"24.9","Cardiomyocytes":"75.6","Cytotrophoblasts":"80.5","Sertoli cells":"24.9","Syncytiotrophoblasts":"35.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"prostate cancer":"12.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"8.1"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067972"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA067972":"AB_2685936"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"ADRB2","Gene synonym":["ADRB2R","ADRBR","B2AR","BAR"],"Ensembl":"ENSG00000169252","Gene description":"Adrenoceptor beta 2","Uniprot":["P07550"],"Chromosome":"5","Position":"148826611-148828623","Protein class":["FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"193.7","Alveolar cells type 1":"120.6","Basal keratinocytes":"285.9","Basal respiratory cells":"139.6","Basal squamous epithelial cells":"176.7","granulocytes":"149.3","Squamous epithelial cells":"275.5","Suprabasal keratinocytes":"168.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"9.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"57.4"},"RNA tissue cell type enrichment":["Colon - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075322"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA075322":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.15e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"}},{"Gene":"ADRB3","Gene synonym":[],"Ensembl":"ENSG00000188778","Gene description":"Adrenoceptor beta 3","Uniprot":["P13945"],"Chromosome":"8","Position":"37962990-37966599","Protein class":["FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Diabetes mellitus","FDA approved drug targets","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.1","ovary":"11.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"1.0","Langerhans cells":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"medulla oblongata":"8.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"135","RNA cell line specific nTPM":{"Bone cancer":"19.1"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061969"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA061969":"AB_2732674"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-3"}},{"Gene":"ADSL","Gene synonym":[],"Ensembl":"ENSG00000239900","Gene description":"Adenylosuccinate lyase","Uniprot":["P30566"],"Chromosome":"22","Position":"40346461-40390463","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Purine biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skeletal muscle":"345.1","tongue":"242.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000525","CAB019285"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"440000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB019285":null,"HPA000525":"AB_1078106"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.38e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.81e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"}},{"Gene":"ADTRP","Gene synonym":["AIG1L","C6orf105","dJ413H6.1"],"Ensembl":"ENSG00000111863","Gene description":"Androgen dependent TFPI regulating protein","Uniprot":["Q96IZ2"],"Chromosome":"6","Position":"11712054-11807046","Protein class":["Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"98.5","parathyroid gland":"92.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"92.1","Distal tubular cells":"77.7","Early spermatids":"125.9","Late spermatids":"188.0","Paneth cells":"58.9","Proximal enterocytes":"130.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"14.8","T-reg":"13.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"14.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048113"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA048113":"AB_2680268"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"}},{"Gene":"AEBP1","Gene synonym":["ACLP"],"Ensembl":"ENSG00000106624","Gene description":"AE binding protein 1","Uniprot":["Q8IUX7"],"Chromosome":"7","Position":"44104345-44114562","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Calmodulin-binding","DNA-binding","Repressor"],"Disease involvement":["Disease variant","Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"103.5","Fibroblasts":"274.8","Leydig cells":"151.0","Melanocytes":"116.7","Peritubular cells":"489.4","Smooth muscle cells":"213.3","Thymic epithelial cells":"114.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"7.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"7.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"59.9","skin cancer":"58.9"},"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Heart muscle - Fibroblasts","Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"57.6"},"Antibody":["CAB009966","HPA047724","HPA063595","HPA064970"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB009966":"AB_2225690","HPA047724":"AB_2680132","HPA063595":"AB_2685052","HPA064970":"AB_2685394"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.31e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"}},{"Gene":"AF196969.1","Gene synonym":[],"Ensembl":"ENSG00000286268","Gene description":"Novel protein","Uniprot":[],"Chromosome":"X","Position":"48521806-48545469","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"2.5","Erythroid cells":"2.3","Gastric mucus-secreting cells":"1.8","granulocytes":"1.6","Plasma cells":"2.6","Squamous epithelial cells":"2.6"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003130"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nuclear membrane","Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA003130":"AB_1078717"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AF241726.1","Gene synonym":[],"Ensembl":"ENSG00000250349","Gene description":"Novel proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1) and tetraspanin 7 (TSPAN7) protein","Uniprot":[],"Chromosome":"X","Position":"37349330-38687674","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"3.1","skeletal muscle":"4.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003140"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003140":"AB_1078454"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AFG3L2","Gene synonym":["SCA28","SPAX5"],"Ensembl":"ENSG00000141385","Gene description":"AFG3 like matrix AAA peptidase subunit 2","Uniprot":["Q9Y4W6"],"Chromosome":"18","Position":"12328944-12377227","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004479","HPA004480"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA004479":"AB_1078109","HPA004480":"AB_1078108"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.68e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.05e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"}},{"Gene":"AGAP1","Gene synonym":["CENTG2","GGAP1","KIAA1099"],"Ensembl":"ENSG00000157985","Gene description":"ArfGAP with GTPase domain, ankyrin repeat and PH domain 1","Uniprot":["Q9UPQ3"],"Chromosome":"2","Position":"235494043-236131800","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"53.9","retina":"54.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"1377.1","Oligodendrocytes":"942.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"1.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"T-cells":"1.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.60e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.75e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.52e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"}},{"Gene":"AGAP5","Gene synonym":["CTGLF2","Em:AC073389.1"],"Ensembl":"ENSG00000172650","Gene description":"ArfGAP with GTPase domain, ankyrin repeat and PH domain 5","Uniprot":["A6NIR3"],"Chromosome":"10","Position":"73674287-73697881","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"4.1","Early spermatids":"2.7","Excitatory neurons":"6.4","Inhibitory neurons":"6.1","Late spermatids":"6.8","Oligodendrocyte precursor cells":"4.3","Oligodendrocytes":"8.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042490"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042490":"AB_2678022"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"}},{"Gene":"AGER","Gene synonym":["RAGE","SCARJ1"],"Ensembl":"ENSG00000204305","Gene description":"Advanced glycosylation end-product specific receptor","Uniprot":["Q15109"],"Chromosome":"6","Position":"32180968-32184322","Protein class":["Cancer-related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Inflammatory response"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"lung":"728.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Alveolar cells type 1":"2508.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"27.2","thyroid cancer":"20.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"2.3"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011682","HPA064436","HPA069474"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Plasma membrane","Cell Junctions"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":5360000,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"CAB011682":"AB_2258049","HPA064436":"AB_2685264","HPA069474":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.41e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.01e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.74e-6"}},{"Gene":"AGL","Gene synonym":[],"Ensembl":"ENSG00000162688","Gene description":"Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase","Uniprot":["P35573"],"Chromosome":"1","Position":"99850361-99924023","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Glycogen biosynthesis"],"Molecular function":["Glycosidase","Glycosyltransferase","Hydrolase","Multifunctional enzyme","Transferase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"257.6","tongue":"212.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"149.7","Muller glia cells":"140.6","Skeletal myocytes":"278.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Gallbladder cancer":"78.2"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028498","HPA054340"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA028498":"AB_10600975","HPA054340":"AB_2682455"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.73e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"}},{"Gene":"AGMO","Gene synonym":["FLJ16237","TMEM195"],"Ensembl":"ENSG00000187546","Gene description":"Alkylglycerol monooxygenase","Uniprot":["Q6ZNB7"],"Chromosome":"7","Position":"15200317-15562015","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"liver":"122.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"75.3","Oligodendrocyte precursor cells":"32.3","Oligodendrocytes":"36.3","Proximal enterocytes":"25.9","Proximal tubular cells":"16.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"15.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"1.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"10.9"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057900"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA057900":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"}},{"Gene":"AGPAT1","Gene synonym":["LPAAT-alpha"],"Ensembl":"ENSG00000204310","Gene description":"1-acylglycerol-3-phosphate O-acyltransferase 1","Uniprot":["Q99943"],"Chromosome":"6","Position":"32168212-32178096","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"101.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"47.1"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048478","HPA073355"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Rods & Rings"],"Antibody RRID":{"HPA048478":"AB_2680411","HPA073355":"AB_2686596"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.93e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.21e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"}},{"Gene":"AGPAT2","Gene synonym":["BSCL","LPAAT-beta"],"Ensembl":"ENSG00000169692","Gene description":"1-acylglycerol-3-phosphate O-acyltransferase 2","Uniprot":["O15120"],"Chromosome":"9","Position":"136673143-136687457","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Congenital generalized lipodystrophy","Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"369.3","liver":"445.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"583.0","Late spermatids":"406.6","Paneth cells":"454.1","Proximal enterocytes":"1318.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019544"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019544":"AB_1844646"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"}},{"Gene":"AGPAT3","Gene synonym":["LPAAT-gamma","LPAAT3"],"Ensembl":"ENSG00000160216","Gene description":"1-acylglycerol-3-phosphate O-acyltransferase 3","Uniprot":["Q9NRZ7"],"Chromosome":"21","Position":"43865223-43987592","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"261.9","Late spermatids":"250.0","Rod photoreceptor cells":"179.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"9.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.31e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"}},{"Gene":"AGPAT4","Gene synonym":["dJ473J16.2","LPAAT-delta"],"Ensembl":"ENSG00000026652","Gene description":"1-acylglycerol-3-phosphate O-acyltransferase 4","Uniprot":["Q9NRZ5"],"Chromosome":"6","Position":"161129967-161274061","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"51.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"384.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053287","HPA060525"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoli","Vesicles"],"Antibody RRID":{"HPA053287":"AB_2682101","HPA060525":"AB_2684306"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.45e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"}},{"Gene":"AGPAT5","Gene synonym":["FLJ11210","LPAAT-e","LPAAT-epsilon"],"Ensembl":"ENSG00000155189","Gene description":"1-acylglycerol-3-phosphate O-acyltransferase 5","Uniprot":["Q9NUQ2"],"Chromosome":"8","Position":"6708642-6761503","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"152.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010644","HPA010950","HPA011646"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA010644":"AB_1844647","HPA010950":"AB_1844648","HPA011646":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.82e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.57e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-3"}},{"Gene":"AGRN","Gene synonym":["AGRIN"],"Ensembl":"ENSG00000188157","Gene description":"Agrin","Uniprot":["O00468"],"Chromosome":"1","Position":"1020120-1056118","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"64.7","Collecting duct cells":"90.6","Ductal cells":"65.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040090"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA040090":"AB_10805603"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"}},{"Gene":"AGTR1","Gene synonym":["AG2S","AGTR1A","AGTR1B","AT1","AT1B","AT2R1","AT2R1A","AT2R1B","HAT1R"],"Ensembl":"ENSG00000144891","Gene description":"Angiotensin II receptor type 1","Uniprot":["P30556"],"Chromosome":"3","Position":"148697784-148743008","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"96.6","placenta":"141.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"44.9","Hepatocytes":"28.7","Leydig cells":"141.7","Sertoli cells":"52.5","Smooth muscle cells":"57.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"breast cancer":"9.6","liver cancer":"9.8","prostate cancer":"6.8","renal cancer":"2.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"8.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"liver cancer":"12.1","Rhabdoid":"6.6"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003596"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA003596":"AB_1845163"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"}},{"Gene":"AGTR2","Gene synonym":["AT2","MRX88"],"Ensembl":"ENSG00000180772","Gene description":"Angiotensin II receptor type 2","Uniprot":["P50052"],"Chromosome":"X","Position":"116170744-116174974","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"8.8","lung":"8.8","smooth muscle":"13.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Alveolar cells type 2":"13.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"endometrial cancer":"3.0","lung cancer":"1.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"Sarcoma":"1.6"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"cerebellum":"2.0"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AGTRAP","Gene synonym":["ATRAP"],"Ensembl":"ENSG00000177674","Gene description":"Angiotensin II receptor associated protein","Uniprot":["Q6RW13"],"Chromosome":"1","Position":"11736084-11754802","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"181.6","Hofbauer cells":"164.9","Kupffer cells":"173.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044120"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA044120":"AB_10960748"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.57e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"}},{"Gene":"AIF1L","Gene synonym":["C9orf58","FLJ12783","IBA2"],"Ensembl":"ENSG00000126878","Gene description":"Allograft inflammatory factor 1 like","Uniprot":["Q9BQI0"],"Chromosome":"9","Position":"131096476-131123152","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"284.4","kidney":"313.2","lymphoid tissue":"206.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"113.0","Collecting duct cells":"303.2","Distal tubular cells":"186.6","Extravillous trophoblasts":"464.8","Proximal tubular cells":"213.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Prostate - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020522","HPA056852"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA020522":"AB_2670463","HPA056852":"AB_2683256"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.54e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"}},{"Gene":"AIFM1","Gene synonym":["AIF","AUNX1","CMTX4","DFNX5","NAMSD","PDCD8"],"Ensembl":"ENSG00000156709","Gene description":"Apoptosis inducing factor mitochondria associated 1","Uniprot":["O95831"],"Chromosome":"X","Position":"130124666-130165879","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["DNA-binding","Oxidoreductase"],"Disease involvement":["Charcot-Marie-Tooth disease","Deafness","Disease variant","Dwarfism","Intellectual disability","Neurodegeneration","Neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"232.2","Proximal tubular cells":"331.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Pancreas - Macrophages","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003764","HPA030611"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"230000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB003764":"AB_289587","HPA030611":"AB_2673549"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.42e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"}},{"Gene":"AIG1","Gene synonym":["AIG-1","dJ95L4.1","FLJ10485"],"Ensembl":"ENSG00000146416","Gene description":"Androgen induced 1","Uniprot":["Q9NVV5"],"Chromosome":"6","Position":"143060496-143341058","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"235.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"249.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060766"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA060766":"AB_2684356"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.26e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.06e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.25e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"}},{"Gene":"AJAP1","Gene synonym":["MOT8","SHREW-1","SHREW1"],"Ensembl":"ENSG00000196581","Gene description":"Adherens junctions associated protein 1","Uniprot":["Q9UKB5"],"Chromosome":"1","Position":"4654609-4792534","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.3","ovary":"4.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"21.6","Cholangiocytes":"15.4","dendritic cells":"19.4","Excitatory neurons":"51.2","Inhibitory neurons":"51.3","Oligodendrocyte precursor cells":"19.7","Oligodendrocytes":"17.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1.8"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"granulocytes":"1.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"8.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.89e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"}},{"Gene":"AKAP1","Gene synonym":["AKAP121","AKAP149","AKAP84","D-AKAP1","PPP1R43","PRKA1","S-AKAP84","SAKAP84","TDRD17"],"Ensembl":"ENSG00000121057","Gene description":"A-kinase anchoring protein 1","Uniprot":["Q92667"],"Chromosome":"17","Position":"57085092-57121346","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"207.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Late spermatids":"2243.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008620","HPA008691","CAB019286"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB019286":null,"HPA008620":"AB_2668104","HPA008691":"AB_1078119"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.86e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"}},{"Gene":"AKAP10","Gene synonym":["D-AKAP2","MGC9414","PRKA10"],"Ensembl":"ENSG00000108599","Gene description":"A-kinase anchoring protein 10","Uniprot":["O43572"],"Chromosome":"17","Position":"19904302-19978343","Protein class":["Disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"69.0","Oligodendrocytes":"74.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"84.8"},"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028901"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028901":"AB_10602227"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"}},{"Gene":"AKAP6","Gene synonym":["ADAP6","AKAP100","KIAA0311","mAKAP","PRKA6"],"Ensembl":"ENSG00000151320","Gene description":"A-kinase anchoring protein 6","Uniprot":["Q13023"],"Chromosome":"14","Position":"32329298-32837684","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"59.8","heart muscle":"54.6","skeletal muscle":"47.5","tongue":"50.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"593.0","Inhibitory neurons":"647.8","Oligodendrocyte precursor cells":"395.2","Oligodendrocytes":"1097.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"naive B-cell":"3.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"3.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"12.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001983","HPA048741"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001983":null,"HPA048741":"AB_2680506"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"}},{"Gene":"AKAP8L","Gene synonym":["HAP95","NAKAP95"],"Ensembl":"ENSG00000011243","Gene description":"A-kinase anchoring protein 8 like","Uniprot":["Q9ULX6"],"Chromosome":"19","Position":"15380050-15419141","Protein class":["Predicted intracellular proteins"],"Biological process":["Host-virus interaction","mRNA processing","mRNA splicing","Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042485","HPA042546"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042485":"AB_2678019","HPA042546":"AB_2678046"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.49e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.04e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-3"}},{"Gene":"AKR1E2","Gene synonym":["AKR1CL2","AKRDC1","htAKR","HTSP1","MGC10612"],"Ensembl":"ENSG00000165568","Gene description":"Aldo-keto reductase family 1 member E2","Uniprot":["Q96JD6"],"Chromosome":"10","Position":"4786629-4848062","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"19.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"122.7","Late spermatids":"187.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"17.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037822"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA037822":"AB_10671722"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"}},{"Gene":"AKTIP","Gene synonym":["FLJ13258","FTS"],"Ensembl":"ENSG00000166971","Gene description":"AKT interacting protein","Uniprot":["Q9H8T0"],"Chromosome":"16","Position":"53491040-53504411","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"361.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Skeletal muscle - Skeletal myocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041794","HPA046300"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041794":"AB_2677677","HPA046300":"AB_2679619"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"}},{"Gene":"AL021546.1","Gene synonym":[],"Ensembl":"ENSG00000111780","Gene description":"Novel protein","Uniprot":[],"Chromosome":"12","Position":"120438198-120460006","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062394"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA062394":"AB_2684749"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL034430.1","Gene synonym":[],"Ensembl":"ENSG00000285508","Gene description":"Novel protein","Uniprot":[],"Chromosome":"20","Position":"10413520-10431922","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"8.2","heart muscle":"8.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL034430.2","Gene synonym":[],"Ensembl":"ENSG00000285723","Gene description":"Novel protein","Uniprot":[],"Chromosome":"20","Position":"10420546-10420737","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"47.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL035460.1","Gene synonym":[],"Ensembl":"ENSG00000241690","Gene description":"Novel protein","Uniprot":[],"Chromosome":"20","Position":"2814968-2818066","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"35","RNA tissue specific nTPM":{"testis":"13.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Late spermatids":"1.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL035461.3","Gene synonym":[],"Ensembl":"ENSG00000286235","Gene description":"Novel protein","Uniprot":[],"Chromosome":"20","Position":"5950949-6039856","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"6.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045141","HPA066433"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":null,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA045141":"AB_2679230","HPA066433":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL121845.3","Gene synonym":[],"Ensembl":"ENSG00000273154","Gene description":"Novel protein, ZGPAT-LIME1 readthrough","Uniprot":[],"Chromosome":"20","Position":"63708864-63739103","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"2.3","Pancreatic endocrine cells":"1.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"}},{"Gene":"AL132671.2","Gene synonym":[],"Ensembl":"ENSG00000282218","Gene description":"Novel protein, GOPC-ROS1 readthrough","Uniprot":[],"Chromosome":"6","Position":"117318211-117573571","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Alveolar cells type 2":"1.0"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019477"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA019477":"AB_1849890"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL136295.1","Gene synonym":[],"Ensembl":"ENSG00000254692","Gene description":"Novel protein","Uniprot":[],"Chromosome":"14","Position":"24189157-24213473","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059249"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA059249":"AB_2683959"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL136295.3","Gene synonym":[],"Ensembl":"ENSG00000259371","Gene description":"Novel protein","Uniprot":[],"Chromosome":"14","Position":"24120956-24131829","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"}},{"Gene":"AL139011.2","Gene synonym":[],"Ensembl":"ENSG00000258465","Gene description":"Novel protein","Uniprot":[],"Chromosome":"1","Position":"160216800-160285130","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"2.3","Rod photoreceptor cells":"1.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.2"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"1.0"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044837"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044837":"AB_10962496"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-3"}},{"Gene":"AL158151.3","Gene synonym":[],"Ensembl":"ENSG00000235007","Gene description":"Novel protein","Uniprot":[],"Chromosome":"9","Position":"129139413-129260575","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD8 T-cell":"2.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"1.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL160272.2","Gene synonym":[],"Ensembl":"ENSG00000285082","Gene description":"Novel protein","Uniprot":[],"Chromosome":"9","Position":"117704157-118072314","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"1.8","brain":"7.0","choroid plexus":"2.3","retina":"2.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Gallbladder cancer":"4.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL353579.1","Gene synonym":[],"Ensembl":"ENSG00000286105","Gene description":"Transmembrane protein 217","Uniprot":[],"Chromosome":"6","Position":"37212181-37257637","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"4.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL391650.1","Gene synonym":[],"Ensembl":"ENSG00000236782","Gene description":"Novel protein","Uniprot":[],"Chromosome":"1","Position":"26169516-26171831","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"retina":"29.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Bipolar cells":"153.3","Horizontal cells":"243.5","Muller glia cells":"211.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"}},{"Gene":"AL451106.1","Gene synonym":[],"Ensembl":"ENSG00000288661","Gene description":"Novel protein","Uniprot":[],"Chromosome":"X","Position":"63754485-63754664","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"3.3","retina":"1.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"1.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 69: BICR 18 - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL590132.1","Gene synonym":[],"Ensembl":"ENSG00000284299","Gene description":"Novel protein","Uniprot":[],"Chromosome":"1","Position":"210858125-211134146","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Pancreatic endocrine cells":"1.7"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 69: BICR 18 - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL592490.1","Gene synonym":[],"Ensembl":"ENSG00000197991","Gene description":"Novel protein","Uniprot":[],"Chromosome":"13","Position":"61409858-61427849","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"23","RNA single cell type specific nTPM":{"Early spermatids":"3.1","Late spermatids":"1.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062669"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA062669":"AB_2732687"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL645941.2","Gene synonym":[],"Ensembl":"ENSG00000248993","Gene description":"Novel  protein","Uniprot":[],"Chromosome":"6","Position":"32937364-32953122","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1.7","Erythroid cells":"1.9","Macrophages":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012298"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012298":"AB_1853927"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL669918.1","Gene synonym":[],"Ensembl":"ENSG00000250264","Gene description":"Novel protein, TAP2-HLA-DOB readthrough","Uniprot":[],"Chromosome":"6","Position":"32813767-32838822","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"11.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"2.0","Gastric mucus-secreting cells":"2.4","Squamous epithelial cells":"1.4","T-cells":"1.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001312"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Nuclear speckles","Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA001312":"AB_1080206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"}},{"Gene":"AL691442.1","Gene synonym":[],"Ensembl":"ENSG00000251246","Gene description":"Novel ephrin-A4 (EFNA4) and ephrin-A3 (EFNA3) protein","Uniprot":[],"Chromosome":"1","Position":"155063748-155086807","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AL845331.1","Gene synonym":[],"Ensembl":"ENSG00000259916","Gene description":"Putative aquaporin-7-like protein 3","Uniprot":[],"Chromosome":"2","Position":"94588522-94604573","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"adipose tissue":"7.5","breast":"1.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"4.4","Early spermatids":"2.3","Excitatory neurons":"2.4","Inhibitory neurons":"1.2","Late spermatids":"2.3","Proximal tubular cells":"1.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"ALCAM","Gene synonym":["CD166","MEMD"],"Ensembl":"ENSG00000170017","Gene description":"Activated leukocyte cell adhesion molecule","Uniprot":["Q13740"],"Chromosome":"3","Position":"105366909-105576900","Protein class":["Cancer-related genes","CD markers","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Adaptive immunity","Cell adhesion","Immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"parathyroid gland":"438.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"295.8","Oligodendrocyte precursor cells":"651.3","Oligodendrocytes":"926.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"29.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"29.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Enteric glia cells","Liver - Hepatocytes","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002148","HPA010926"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB002148":"AB_442053","HPA010926":"AB_1078449"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.15e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"}},{"Gene":"ALDH3A2","Gene synonym":["ALDH10","FALDH","SLS"],"Ensembl":"ENSG00000072210","Gene description":"Aldehyde dehydrogenase 3 family member A2","Uniprot":["P51648"],"Chromosome":"17","Position":"19648136-19685760","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Ichthyosis","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"288.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"249.0","Basal squamous epithelial cells":"284.7","Squamous epithelial cells":"224.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Alveolar cells type 1","Skin - Keratinocyte (other)","Testis - Leydig cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014769","CAB020692"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"32000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB020692":null,"HPA014769":"AB_1844728"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.85e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"}},{"Gene":"ALDH5A1","Gene synonym":["SSADH","SSDH"],"Ensembl":"ENSG00000112294","Gene description":"Aldehyde dehydrogenase 5 family member A1","Uniprot":["P51649"],"Chromosome":"6","Position":"24494867-24537207","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"98.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"40.4","Hepatocytes":"82.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"44.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Skeletal muscle - Skeletal myocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029715","HPA029716"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA029715":"AB_10599994","HPA029716":"AB_10601876"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.61e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.20e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.68e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"}},{"Gene":"ALG1","Gene synonym":["CDG1K","HMAT1","HMT-1","Mat-1"],"Ensembl":"ENSG00000033011","Gene description":"ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase","Uniprot":["Q9BT22"],"Chromosome":"16","Position":"5033923-5087379","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060392"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA060392":"AB_2684273"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.79e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.93e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"}},{"Gene":"ALG10","Gene synonym":["ALG10A","DIE2","FLJ14751"],"Ensembl":"ENSG00000139133","Gene description":"ALG10 alpha-1,2-glucosyltransferase","Uniprot":["Q5BKT4"],"Chromosome":"12","Position":"34022468-34029694","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"12.1","Spermatocytes":"12.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043329","HPA063387"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA043329":"AB_2678432","HPA063387":"AB_2685000"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"}},{"Gene":"ALG10B","Gene synonym":["KCR1"],"Ensembl":"ENSG00000175548","Gene description":"ALG10 alpha-1,2-glucosyltransferase B","Uniprot":["Q5I7T1"],"Chromosome":"12","Position":"38316762-38329721","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043329","HPA063387"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA043329":"AB_2678432","HPA063387":"AB_2685000"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"}},{"Gene":"ALG11","Gene synonym":["CDG1P","KIAA0266"],"Ensembl":"ENSG00000253710","Gene description":"ALG11 alpha-1,2-mannosyltransferase","Uniprot":["Q2TAA5"],"Chromosome":"13","Position":"52012391-52079232","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047214"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047214":"AB_10961640"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-3"}},{"Gene":"ALG12","Gene synonym":["CDG1G","ECM39"],"Ensembl":"ENSG00000182858","Gene description":"ALG12 alpha-1,6-mannosyltransferase","Uniprot":["Q9BV10"],"Chromosome":"22","Position":"49900229-49918438","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003076","HPA051665"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA003076":"AB_2666777","HPA051665":"AB_2681566"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.09e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.60e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"}},{"Gene":"ALG14","Gene synonym":["MGC19780"],"Ensembl":"ENSG00000172339","Gene description":"ALG14 UDP-N-acetylglucosaminyltransferase subunit","Uniprot":["Q96F25"],"Chromosome":"1","Position":"94974405-95072951","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant","Epilepsy","Intellectual disability","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031829"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA031829":"AB_2674062"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"}},{"Gene":"ALG3","Gene synonym":["CDGS4","D16Ertd36e","Not56","NOT56L"],"Ensembl":"ENSG00000214160","Gene description":"ALG3 alpha-1,3- mannosyltransferase","Uniprot":["Q92685"],"Chromosome":"3","Position":"184242301-184249548","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"238.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045103"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045103":"AB_10960547"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.58e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.67e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"}},{"Gene":"ALG6","Gene synonym":[],"Ensembl":"ENSG00000088035","Gene description":"ALG6 alpha-1,3-glucosyltransferase","Uniprot":["Q9Y672"],"Chromosome":"1","Position":"63367575-63438553","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"42.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062536","HPA076130"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA062536":"AB_2684792","HPA076130":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.86e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.46e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.63e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"}},{"Gene":"ALG8","Gene synonym":["MGC2840"],"Ensembl":"ENSG00000159063","Gene description":"ALG8 alpha-1,3-glucosyltransferase","Uniprot":["Q9BVK2"],"Chromosome":"11","Position":"78095244-78139660","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"101.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051898"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA051898":"AB_2681656"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"}},{"Gene":"ALG9","Gene synonym":["DIBD1"],"Ensembl":"ENSG00000086848","Gene description":"ALG9 alpha-1,2-mannosyltransferase","Uniprot":["Q9H6U8"],"Chromosome":"11","Position":"111782195-111871581","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"26.2","Inhibitory neurons":"31.1","Oligodendrocytes":"30.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038575"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA038575":"AB_10672718"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"}},{"Gene":"ALK","Gene synonym":["CD246"],"Ensembl":"ENSG00000171094","Gene description":"ALK receptor tyrosine kinase","Uniprot":["Q9UM73"],"Chromosome":"2","Position":"29192774-29921586","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"10.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Inhibitory neurons":"267.4","Oligodendrocyte precursor cells":"415.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"1.0","melanoma":"1.5","ovarian cancer":"0.7","thyroid cancer":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Neuroblastoma":"81.3"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010694"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA010694":"AB_1078133"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"}},{"Gene":"ALOX5AP","Gene synonym":["FLAP"],"Ensembl":"ENSG00000132965","Gene description":"Arachidonate 5-lipoxygenase activating protein","Uniprot":["P20292"],"Chromosome":"13","Position":"30713478-30764426","Protein class":["Disease related genes","Predicted membrane proteins"],"Biological process":["Leukotriene biosynthesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"487.2","lung":"183.3","lymphoid tissue":"138.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"1312.6","granulocytes":"632.3","Hofbauer cells":"501.4","Langerhans cells":"421.8","Macrophages":"563.9","NK-cells":"345.3","T-cells":"308.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"49.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"9703.9","eosinophil":"4033.4","neutrophil":"4968.7","plasmacytoid DC":"3555.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"3555.3","granulocytes":"9703.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"131.8","lymphoma":"164.0","Myeloma":"44.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Neutrophils","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026592"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026592":"AB_10601115"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.44e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.68e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"}},{"Gene":"ALPG","Gene synonym":["ALPPL2","GCAP"],"Ensembl":"ENSG00000163286","Gene description":"Alkaline phosphatase, germ cell","Uniprot":["P10696"],"Chromosome":"2","Position":"232406844-232410714","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"2.5","Spermatogonia":"1.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"49.1","testis cancer":"64.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"21.6","testis cancer":"38.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020698","HPA038764","HPA038765","HPA051699"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB020698":null,"HPA038764":"AB_2676194","HPA038765":"AB_2676195","HPA051699":"AB_2681577"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"}},{"Gene":"ALPI","Gene synonym":["IAP"],"Ensembl":"ENSG00000163295","Gene description":"Alkaline phosphatase, intestinal","Uniprot":["P09923"],"Chromosome":"2","Position":"232456125-232460753","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"138","RNA tissue specific nTPM":{"intestine":"141.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Proximal enterocytes":"296.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"4.7","renal cancer":"3.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038764","HPA038765","HPA051699"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA038764":"AB_2676194","HPA038765":"AB_2676195","HPA051699":"AB_2681577"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-4"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ALPK1","Gene synonym":["FLJ22670","KIAA1527","Lak"],"Ensembl":"ENSG00000073331","Gene description":"Alpha kinase 1","Uniprot":["Q96QP1"],"Chromosome":"4","Position":"112285509-112442621","Protein class":["Enzymes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation","Immunity","Innate immunity"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"71.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"18.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027435","HPA027443"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA027435":"AB_10599614","HPA027443":"AB_10599421"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.82e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.17e-4"}},{"Gene":"ALPL","Gene synonym":["HOPS","TNALP","TNAP","TNSALP"],"Ensembl":"ENSG00000162551","Gene description":"Alkaline phosphatase, biomineralization associated","Uniprot":["P05186"],"Chromosome":"1","Position":"21509397-21578410","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biomineralization"],"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"60.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Alveolar cells type 2":"304.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"199.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"90","RNA blood cell specific nTPM":{"neutrophil":"379.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"139","RNA blood lineage specific nTPM":{"granulocytes":"379.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"80.3","Gallbladder cancer":"20.3","ovarian cancer":"25.4","Sarcoma":"33.4","testis cancer":"48.1"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Skeletal muscle - Neutrophils","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007105","HPA008765","CAB020829"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB020829":null,"HPA007105":"AB_1078137","HPA008765":"AB_1078138"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.57e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.08e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"}},{"Gene":"ALPP","Gene synonym":["PALP","PLAP"],"Ensembl":"ENSG00000163283","Gene description":"Alkaline phosphatase, placental","Uniprot":["P05187"],"Chromosome":"2","Position":"232378724-232382889","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"cervix":"17.8","placenta":"34.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Alveolar cells type 1":"58.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"15.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"75.3","Gastric cancer":"67.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026327","HPA038764","HPA038765","HPA051699"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB026327":null,"HPA038764":"AB_2676194","HPA038765":"AB_2676195","HPA051699":"AB_2681577"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.33e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"}},{"Gene":"AMDHD2","Gene synonym":["CGI-14"],"Ensembl":"ENSG00000162066","Gene description":"Amidohydrolase domain containing 2","Uniprot":["Q9Y303"],"Chromosome":"16","Position":"2520357-2531422","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"65.4","Hofbauer cells":"114.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Lung - Macrophages","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041184","HPA041321"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041184":"AB_10803998","HPA041321":"AB_10795588"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.19e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"}},{"Gene":"AMFR","Gene synonym":["gp78","RNF45"],"Ensembl":"ENSG00000159461","Gene description":"Autocrine motility factor receptor","Uniprot":["Q9UKV5"],"Chromosome":"16","Position":"56361452-56425545","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Receptor","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"141.9","Hepatocytes":"135.5","Late spermatids":"130.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026381","HPA029018","HPA064339","HPA077835"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Endoplasmic reticulum","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB026381":null,"HPA029018":"AB_2672869","HPA064339":null,"HPA077835":"AB_2686856"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"}},{"Gene":"AMHR2","Gene synonym":["MISR2","MISRII"],"Ensembl":"ENSG00000135409","Gene description":"Anti-Mullerian hormone receptor type 2","Uniprot":["Q16671"],"Chromosome":"12","Position":"53423855-53431672","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Pseudohermaphroditism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"41.5","ovary":"33.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"granulocytes":"21.2","Granulosa cells":"37.3","Sertoli cells":"22.1","Theca cells":"77.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"5.3","liver cancer":"4.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Adipose visceral - Mesothelial cells","Colon - Mast cells","Liver - Sinusoid Endothelial cells","Pancreas - Exocrine glandular cells","Skin - Mast cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"11","RNA pig brain regional specific nTPM":{"hippocampal formation":"9.4"},"Antibody":["HPA060228","HPA069636"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA060228":"AB_2684227","HPA069636":"AB_2686163"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"}},{"Gene":"AMIGO1","Gene synonym":["AMIGO","KIAA1163"],"Ensembl":"ENSG00000181754","Gene description":"Adhesion molecule with Ig like domain 1","Uniprot":["Q86WK6"],"Chromosome":"1","Position":"109504178-109509738","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"30.8","Cone photoreceptor cells":"10.3","Horizontal cells":"18.6","Inhibitory neurons":"15.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"2.3"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"T-cells":"2.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046152"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA046152":"AB_2679559"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.21e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"}},{"Gene":"AMIGO2","Gene synonym":["ALI1","DEGA"],"Ensembl":"ENSG00000139211","Gene description":"Adhesion molecule with Ig like domain 2","Uniprot":["Q86SJ2"],"Chromosome":"12","Position":"47075707-47079959","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"49.2","Breast myoepithelial cells":"42.2","Glandular and luminal cells":"66.9","Granulosa cells":"76.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"210.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Breast - Breast myoepithelial cells","Skeletal muscle - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054004","HPA059601"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"390000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA054004":"AB_2682339","HPA059601":"AB_2684078"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.80e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"}},{"Gene":"AMIGO3","Gene synonym":[],"Ensembl":"ENSG00000176020","Gene description":"Adhesion molecule with Ig like domain 3","Uniprot":["Q86WK7"],"Chromosome":"3","Position":"49716829-49719684","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1.3","Intestinal goblet cells":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"plasmacytoid DC":"11.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"11.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-3"}},{"Gene":"AMMECR1L","Gene synonym":["MGC4268"],"Ensembl":"ENSG00000144233","Gene description":"AMMECR1 like","Uniprot":["Q6DCA0"],"Chromosome":"2","Position":"127861630-127885967","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000590","HPA057234"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA000590":"AB_2666037","HPA057234":"AB_2683376"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.10e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"}},{"Gene":"AMN","Gene synonym":["amnionless"],"Ensembl":"ENSG00000166126","Gene description":"Amnion associated transmembrane protein","Uniprot":["Q9BXJ7"],"Chromosome":"14","Position":"102922663-102933596","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"83.5","kidney":"39.8","liver":"37.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal enterocytes":"560.8","Proximal enterocytes":"1919.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"6.3","Gastric cancer":"5.1","liver cancer":"6.1"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Pancreas - Ductal cells","Prostate - Urothelial cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000817"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000817":"AB_1078146"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.62e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"}},{"Gene":"AMN1","Gene synonym":[],"Ensembl":"ENSG00000151743","Gene description":"Antagonist of mitotic exit network 1 homolog","Uniprot":["Q8IY45"],"Chromosome":"12","Position":"31671142-31729121","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"56.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"437.5","Late spermatids":"168.9","Spermatocytes":"199.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"51.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046157","HPA062290"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA046157":"AB_10965846","HPA062290":"AB_2684739"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"}},{"Gene":"ANAPC1","Gene synonym":["APC1","MCPR","TSG24"],"Ensembl":"ENSG00000153107","Gene description":"Anaphase promoting complex subunit 1","Uniprot":["Q9H1A4"],"Chromosome":"2","Position":"111611639-111884690","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","Mitosis","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Ectodermal dysplasia","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036329","HPA036330","HPA042998"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036329":"AB_10670714","HPA036330":"AB_2675065","HPA042998":"AB_2678263"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"}},{"Gene":"ANAPC5","Gene synonym":["APC5"],"Ensembl":"ENSG00000089053","Gene description":"Anaphase promoting complex subunit 5","Uniprot":["Q9UJX4"],"Chromosome":"12","Position":"121308245-121399896","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039457","HPA039801"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA039457":"AB_10795676","HPA039801":"AB_2676687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.31e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.01e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"}},{"Gene":"ANK3","Gene synonym":[],"Ensembl":"ENSG00000151150","Gene description":"Ankyrin 3","Uniprot":["Q12955"],"Chromosome":"10","Position":"60026298-60733490","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"469.5","Excitatory neurons":"846.0","Inhibitory neurons":"859.4","Oligodendrocyte precursor cells":"567.5","Oligodendrocytes":"1491.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Liver - Hepatic stellate cells","Lung - Alveolar cells type 2","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013249","CAB015179","HPA038455"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB013249":"AB_2533145","CAB015179":"AB_633909","HPA038455":"AB_2676020"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.88e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"}},{"Gene":"ANKAR","Gene synonym":["FLJ25415"],"Ensembl":"ENSG00000151687","Gene description":"Ankyrin and armadillo repeat containing","Uniprot":["Q7Z5J8"],"Chromosome":"2","Position":"189674290-189761193","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"testis":"5.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"80.3","Early spermatids":"96.7","Inhibitory neurons":"59.1","Oligodendrocyte precursor cells":"83.3","Oligodendrocytes":"76.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036168"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA036168":"AB_10673345"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"}},{"Gene":"ANKH","Gene synonym":["ANK","CCAL2","CMDJ","CPPDD","HANK","SLC62A1"],"Ensembl":"ENSG00000154122","Gene description":"ANKH inorganic pyrophosphate transport regulator","Uniprot":["Q9HCJ1"],"Chromosome":"5","Position":"14704800-14871778","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Phosphate transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"157.7","Hofbauer cells":"195.2","Inhibitory neurons":"209.1","Oligodendrocytes":"246.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068104"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA068104":"AB_2685954"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.62e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"}},{"Gene":"ANKLE1","Gene synonym":["ANKRD41","FLJ39369","LEMD6"],"Ensembl":"ENSG00000160117","Gene description":"Ankyrin repeat and LEM domain containing 1","Uniprot":["Q8NAG6"],"Chromosome":"19","Position":"17281645-17287646","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Endonuclease","Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"25.6","brain":"8.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Erythroid cells":"55.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"25.7","lymphoma":"31.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026789","HPA073498"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA026789":"AB_10611675","HPA073498":"AB_2686612"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.86e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"}},{"Gene":"ANKLE2","Gene synonym":["KIAA0692","Lem4","LEMD7"],"Ensembl":"ENSG00000176915","Gene description":"Ankyrin repeat and LEM domain containing 2","Uniprot":["Q86XL3"],"Chromosome":"12","Position":"132725503-132761832","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":["Disease variant","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"196.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003602","HPA074838"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA003602":"AB_1858349","HPA074838":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.97e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"}},{"Gene":"ANKRD29","Gene synonym":["FLJ25053"],"Ensembl":"ENSG00000154065","Gene description":"Ankyrin repeat domain 29","Uniprot":["Q8N6D5"],"Chromosome":"18","Position":"23598926-23662911","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"165.9","Alveolar cells type 1":"274.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041272","HPA049419"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA041272":"AB_2677387","HPA049419":"AB_2680757"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.92e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.98e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.20e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-5"}},{"Gene":"ANKRD46","Gene synonym":[],"Ensembl":"ENSG00000186106","Gene description":"Ankyrin repeat domain 46","Uniprot":["Q86W74"],"Chromosome":"8","Position":"100509752-100559784","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013758"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA013758":"AB_10962626"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-3"}},{"Gene":"ANKRD49","Gene synonym":["FGIF","FLJ20189","GBIF"],"Ensembl":"ENSG00000168876","Gene description":"Ankyrin repeat domain 49","Uniprot":["Q8WVL7"],"Chromosome":"11","Position":"94493979-94499578","Protein class":["Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040273","HPA048137"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA040273":"AB_10674991","HPA048137":"AB_2680279"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.16e-4"}},{"Gene":"ANKRD7","Gene synonym":["TSA806"],"Ensembl":"ENSG00000106013","Gene description":"Ankyrin repeat domain 7","Uniprot":["Q92527"],"Chromosome":"7","Position":"118214669-118496171","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"431","RNA tissue specific nTPM":{"testis":"860.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Early spermatids":"3709.6","Late spermatids":"1054.5","Spermatocytes":"2593.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043489","HPA052941"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA043489":"AB_10959304","HPA052941":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-4"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"}},{"Gene":"ANKS1A","Gene synonym":["ANKS1","KIAA0229"],"Ensembl":"ENSG00000064999","Gene description":"Ankyrin repeat and sterile alpha motif domain containing 1A","Uniprot":["Q92625"],"Chromosome":"6","Position":"34889255-35091406","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"92.7","Inhibitory neurons":"157.2","Microglial cells":"164.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036768","HPA036769"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA036768":"AB_10670923","HPA036769":"AB_10672473"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.48e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.05e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"}},{"Gene":"ANKS1B","Gene synonym":["AIDA-1","ANKS2","cajalin-2","EB-1"],"Ensembl":"ENSG00000185046","Gene description":"Ankyrin repeat and sterile alpha motif domain containing 1B","Uniprot":["Q7Z6G8"],"Chromosome":"12","Position":"98726457-99984654","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"77.0","skeletal muscle":"34.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"2192.2","Inhibitory neurons":"1509.3","Oligodendrocyte precursor cells":"1262.1","Oligodendrocytes":"944.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078230"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA078230":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"}},{"Gene":"ANKUB1","Gene synonym":["C3orf16"],"Ensembl":"ENSG00000206199","Gene description":"Ankyrin repeat and ubiquitin domain containing 1","Uniprot":["A6NFN9"],"Chromosome":"3","Position":"149761100-149968385","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"5.1","choroid plexus":"6.9","fallopian tube":"5.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"126.6","Respiratory ciliated cells":"99.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"1.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"1.6"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053749"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053749":"AB_2682248"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-4"}},{"Gene":"ANO1","Gene synonym":["DOG1","FLJ10261","ORAOV2","TAOS2","TMEM16A"],"Ensembl":"ENSG00000131620","Gene description":"Anoctamin 1","Uniprot":["Q5XXA6"],"Chromosome":"11","Position":"70078302-70189528","Protein class":["FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Developmental protein","Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"181.7","salivary gland":"180.5","seminal vesicle":"209.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"124.8","Breast myoepithelial cells":"72.3","Hepatocytes":"120.1","Late spermatids":"80.7","Serous glandular cells":"71.1","Smooth muscle cells":"44.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Esophageal cancer":"114.2","pancreatic cancer":"104.5"},"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Kidney - Fibroblasts","Liver - Hepatocytes","Skin - Keratinocyte (other)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"6.6"},"Antibody":["HPA032148","HPA057356"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA032148":"AB_2674180","HPA057356":"AB_2732610"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.58e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.28e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.40e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.09e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"}},{"Gene":"ANO10","Gene synonym":["FLJ10375","MGC47890","SCAR10","TMEM16K"],"Ensembl":"ENSG00000160746","Gene description":"Anoctamin 10","Uniprot":["Q9NW15"],"Chromosome":"3","Position":"43354859-43691594","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"77.7","Excitatory neurons":"76.3","Inhibitory neurons":"95.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016624","HPA051569"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA016624":null,"HPA051569":"AB_2681537"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.70e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.41e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"}},{"Gene":"ANO2","Gene synonym":["C12orf3","TMEM16B"],"Ensembl":"ENSG00000047617","Gene description":"Anoctamin 2","Uniprot":["Q9NQ90"],"Chromosome":"12","Position":"5531869-5946232","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"retina":"226.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"289.5","Microglial cells":"139.6","Rod photoreceptor cells":"186.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"granulocytes":"1.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Colon - Endothelial cells","Prostate - Endothelial cells","Skin - Endothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"19.6"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036276","HPA057499"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA036276":"AB_10670713","HPA057499":"AB_2732613"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"}},{"Gene":"ANO3","Gene synonym":["C11orf25","DYT23","GENX-3947","TMEM16C"],"Ensembl":"ENSG00000134343","Gene description":"Anoctamin 3","Uniprot":["Q9BYT9"],"Chromosome":"11","Position":"26188842-26663289","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"brain":"59.2","epididymis":"57.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"199.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"59.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"Rhabdoid":"8.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"158.9"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"basal ganglia":"180.1"},"Antibody":["HPA041629"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041629":"AB_10793969"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"}},{"Gene":"ANO4","Gene synonym":["FLJ34221","FLJ34272","FLJ35277","TMEM16D"],"Ensembl":"ENSG00000151572","Gene description":"Anoctamin 4","Uniprot":["Q32M45"],"Chromosome":"12","Position":"100717526-101128641","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"12.0","brain":"11.3","cervix":"7.6","ovary":"7.7","seminal vesicle":"8.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Inhibitory neurons":"524.3","Oligodendrocyte precursor cells":"265.2","Oligodendrocytes":"768.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"2.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"5.3","testis cancer":"7.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053412"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053412":"AB_2682140"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.48e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"}},{"Gene":"ANO5","Gene synonym":["GDD1","LGMD2L","TMEM16E"],"Ensembl":"ENSG00000171714","Gene description":"Anoctamin 5","Uniprot":["Q75V66"],"Chromosome":"11","Position":"21799934-22283357","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Limb-girdle muscular dystrophy","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"24.9","parathyroid gland":"17.0","skeletal muscle":"65.5","tongue":"50.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"65.8","Cardiomyocytes":"99.0","Excitatory neurons":"164.5","Inhibitory neurons":"133.2","Oligodendrocyte precursor cells":"78.0","Skeletal myocytes":"81.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"4.4"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Skin - Eccrine sweat gland cells","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058857"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058857":"AB_2683835"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.50e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"}},{"Gene":"ANO6","Gene synonym":["DKFZp313M0720","TMEM16F"],"Ensembl":"ENSG00000177119","Gene description":"Anoctamin 6","Uniprot":["Q4KMQ2"],"Chromosome":"12","Position":"45215987-45482280","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction","Ion transport","Lipid transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038958"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"47000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038958":"AB_10672835"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.56e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.82e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"}},{"Gene":"ANO7","Gene synonym":["IPCA-5","NGEP","PCANAP5","PCANAP5L","TMEM16G"],"Ensembl":"ENSG00000146205","Gene description":"Anoctamin 7","Uniprot":["Q6IWH7"],"Chromosome":"2","Position":"241188509-241225377","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"16.3","prostate":"69.6","stomach 1":"28.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"67.4","Intestinal goblet cells":"61.6","Prostatic glandular cells":"69.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"19","RNA cancer specific FPKM":{"prostate cancer":"32.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"6.6"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Prostate - Prostate glandular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078464"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078464":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"}},{"Gene":"ANO8","Gene synonym":["KIAA1623","TMEM16H"],"Ensembl":"ENSG00000074855","Gene description":"Anoctamin 8","Uniprot":["Q9HCE9"],"Chromosome":"19","Position":"17323223-17334855","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"70.9","Inhibitory neurons":"18.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049206"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049206":"AB_2680675"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"}},{"Gene":"ANO9","Gene synonym":["PIG5","TMEM16J","TP53I5"],"Ensembl":"ENSG00000185101","Gene description":"Anoctamin 9","Uniprot":["A1A5B4"],"Chromosome":"11","Position":"417933-442011","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Lipid metabolism","Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"34.2","skin 1":"27.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"59.6","Intestinal goblet cells":"47.4","Paneth cells":"31.7","Proximal enterocytes":"76.3","Undifferentiated cells":"38.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"26.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"48","RNA blood lineage specific nTPM":{"B-cells":"2.1","NK-cells":"4.1","T-cells":"8.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"17.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Liver - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039948","HPA040112"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA039948":"AB_2676765","HPA040112":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.81e-4"}},{"Gene":"ANPEP","Gene synonym":["CD13","gp150","LAP1","p150","PEPN"],"Ensembl":"ENSG00000166825","Gene description":"Alanyl aminopeptidase, membrane","Uniprot":["P15144"],"Chromosome":"15","Position":"89784895-89815401","Protein class":["CD markers","Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Differentiation","Host-virus interaction"],"Molecular function":["Aminopeptidase","Developmental protein","Host cell receptor for virus entry","Hydrolase","Metalloprotease","Protease","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"2384.1","pancreas":"675.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Proximal enterocytes":"5985.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"9.2","thalamus":"17.4"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"227.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"227.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"133.2"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes","Prostate - Prostate glandular cells","Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"spinal cord":"14.8"},"Antibody":["CAB002417","HPA004625"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002417":"AB_563491","HPA004625":"AB_2667199"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"}},{"Gene":"ANTXR1","Gene synonym":["ATR","FLJ10601","FLJ21776","TEM8"],"Ensembl":"ENSG00000169604","Gene description":"ANTXR cell adhesion molecule 1","Uniprot":["Q9H6X2"],"Chromosome":"2","Position":"69013176-69249327","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"126.5","Endometrial stromal cells":"83.0","Oligodendrocyte precursor cells":"135.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"162.3"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Kidney - Fibroblasts","Liver - Hepatic stellate cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054785"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"11000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA054785":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.76e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.22e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"}},{"Gene":"ANTXR2","Gene synonym":["CMG-2","CMG2","FLJ31074"],"Ensembl":"ENSG00000163297","Gene description":"ANTXR cell adhesion molecule 2","Uniprot":["P58335"],"Chromosome":"4","Position":"79901146-80125454","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Prostatic glandular cells":"80.2","Schwann cells":"101.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.34e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"}},{"Gene":"ANTXRL","Gene synonym":[],"Ensembl":"ENSG00000274209","Gene description":"ANTXR like","Uniprot":["A6NF34"],"Chromosome":"10","Position":"46286345-46330207","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"testis":"12.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"41","RNA single cell type specific nTPM":{"Early spermatids":"62.1","Late spermatids":"29.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"ovarian cancer":"0.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"1.1"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"}},{"Gene":"ANXA2R","Gene synonym":["AXIIR","C5orf39"],"Ensembl":"ENSG00000177721","Gene description":"Annexin A2 receptor","Uniprot":["Q3ZCQ2"],"Chromosome":"5","Position":"43039233-43043170","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"19.8","lymphoid tissue":"26.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"33.3","B-cells":"23.6","Endothelial cells":"22.8","Kupffer cells":"18.4","NK-cells":"41.6","T-cells":"61.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"gdT-cell":"53.9","MAIT T-cell":"63.5","memory B-cell":"34.3","memory CD4 T-cell":"56.1","memory CD8 T-cell":"59.9","naive B-cell":"32.9","naive CD4 T-cell":"96.3","naive CD8 T-cell":"72.1","NK-cell":"24.8","T-reg":"66.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"34.3","NK-cells":"24.8","T-cells":"96.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"26.5"},"RNA tissue cell type enrichment":["Colon - Endothelial cells","Liver - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051482"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol","Cytoplasmic bodies"],"Antibody RRID":{"HPA051482":"AB_2681500"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.36e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"}},{"Gene":"ANXA6","Gene synonym":["ANX6"],"Ensembl":"ENSG00000197043","Gene description":"Annexin A6","Uniprot":["P08133"],"Chromosome":"5","Position":"151100706-151157785","Protein class":["Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"332.5","Peritubular cells":"215.1","Syncytiotrophoblasts":"232.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Colon - Smooth muscle cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002462","CAB005077","HPA009650","HPA009977"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005077":"AB_630873","HPA002462":"AB_1078166","HPA009650":"AB_1844867","HPA009977":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"}},{"Gene":"ANXA8","Gene synonym":["ANX8"],"Ensembl":"ENSG00000265190","Gene description":"Annexin A8","Uniprot":["P13928"],"Chromosome":"10","Position":"47460162-47484158","Protein class":["Predicted intracellular proteins"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"217.6","skin 1":"266.2","vagina":"110.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"46.3","Basal respiratory cells":"45.2","Excitatory neurons":"47.1","Inhibitory neurons":"40.0","Oligodendrocyte precursor cells":"48.6","Oligodendrocytes":"45.5","Squamous epithelial cells":"66.9","Suprabasal keratinocytes":"79.3","Thymic epithelial cells":"143.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"14.3","head and neck cancer":"16.1","lung cancer":"4.3","urothelial cancer":"11.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"250.6"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Prostate - Urothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045246","HPA047451"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA045246":"AB_2679271","HPA047451":"AB_2680052"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.07e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.68e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"}},{"Gene":"ANXA8L1","Gene synonym":["ANXA8L2","bA145E20.2","bA301J7.3"],"Ensembl":"ENSG00000264230","Gene description":"Annexin A8 like 1","Uniprot":["Q5VT79"],"Chromosome":"10","Position":"46375627-46391784","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"195.2","skin 1":"325.4","vagina":"100.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"24.5","Basal respiratory cells":"41.0","Basal squamous epithelial cells":"37.2","Squamous epithelial cells":"133.2","Suprabasal keratinocytes":"41.2","Thymic epithelial cells":"55.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"5.2","head and neck cancer":"5.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.2","myeloid DC":"2.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"156.9","head and neck cancer":"228.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 1","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045246","HPA047451"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA045246":"AB_2679271","HPA047451":"AB_2680052"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"AP000350.4","Gene synonym":[],"Ensembl":"ENSG00000251357","Gene description":"Novel protein","Uniprot":[],"Chromosome":"22","Position":"23862188-23895223","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042960"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042960":"AB_2678241"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AP000471.1","Gene synonym":[],"Ensembl":"ENSG00000286224","Gene description":"Novel protein","Uniprot":[],"Chromosome":"21","Position":"46326288-46326491","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.6","skin 1":"1.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AP000781.2","Gene synonym":[],"Ensembl":"ENSG00000254979","Gene description":"Novel protein","Uniprot":[],"Chromosome":"11","Position":"57387365-57424059","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"13.3","liver":"7.2","placenta":"7.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"3.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"3.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"13.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038515"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038515":"AB_10675800"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"}},{"Gene":"AP000812.4","Gene synonym":[],"Ensembl":"ENSG00000284922","Gene description":"Leucine rich transmembrane and O-methyltransferase domain containing","Uniprot":["Q8WZ04"],"Chromosome":"11","Position":"72080331-72110782","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Catecholamine metabolism","Hearing","Neurotransmitter degradation"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"fallopian tube":"14.1","testis":"9.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"15.6","Late spermatids":"33.5"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039949"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA039949":"AB_10960708"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AP001781.2","Gene synonym":[],"Ensembl":"ENSG00000258529","Gene description":"Novel protein","Uniprot":[],"Chromosome":"11","Position":"111786286-111879425","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038575"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA038575":"AB_10672718"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AP002512.3","Gene synonym":[],"Ensembl":"ENSG00000284732","Gene description":"Novel olfactory receptor","Uniprot":[],"Chromosome":"11","Position":"56459221-56473352","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AP002748.5","Gene synonym":[],"Ensembl":"ENSG00000256349","Gene description":"Novel protein","Uniprot":[],"Chromosome":"11","Position":"66509079-66533613","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.9","choroid plexus":"1.9","retina":"2.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058283"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Midbody"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":null,"Subcellular main location":["Midbody"],"Subcellular additional location":null,"Antibody RRID":{"HPA058283":"AB_2683667"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AP2M1","Gene synonym":["AP50","CLAPM1","mu2"],"Ensembl":"ENSG00000161203","Gene description":"Adaptor related protein complex 2 subunit mu 1","Uniprot":["Q96CW1"],"Chromosome":"3","Position":"184174689-184184091","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Endocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036849","HPA069870"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7500","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA036849":"AB_10672101","HPA069870":"AB_2686217"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.12e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.45e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"}},{"Gene":"AP3S2","Gene synonym":["sigma3b"],"Ensembl":"ENSG00000157823","Gene description":"Adaptor related protein complex 3 subunit sigma 2","Uniprot":["P59780"],"Chromosome":"15","Position":"89830599-89894638","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049270"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049270":"AB_2680696"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.55e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-3"}},{"Gene":"AP5B1","Gene synonym":["AP-5","DKFZp761E198","PP1030"],"Ensembl":"ENSG00000254470","Gene description":"Adaptor related protein complex 5 subunit beta 1","Uniprot":["Q2VPB7"],"Chromosome":"11","Position":"65773898-65780976","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"44.0"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"neutrophil":"25.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"granulocytes":"25.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065739","HPA067880"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA065739":"AB_2685550","HPA067880":"AB_2685914"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"}},{"Gene":"AP5S1","Gene synonym":["C20orf29","FLJ11168"],"Ensembl":"ENSG00000125843","Gene description":"Adaptor related protein complex 5 subunit sigma 1","Uniprot":["Q9NUS5"],"Chromosome":"20","Position":"3820524-3828838","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034200","HPA043533","HPA048244"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034200":"AB_1564201","HPA043533":"AB_2732507","HPA048244":"AB_2680328"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.53e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"}},{"Gene":"APAF1","Gene synonym":["APAF-1","CED4"],"Ensembl":"ENSG00000120868","Gene description":"Apoptotic peptidase activating factor 1","Uniprot":["O14727"],"Chromosome":"12","Position":"98645290-98735433","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"32.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"47.9","monocytes":"50.0","Schwann cells":"62.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"71.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031373","CAB069399"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB069399":"AB_1611908","HPA031373":"AB_10602230"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.90e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"}},{"Gene":"APC","Gene synonym":["DP2","DP2.5","DP3","PPP1R46"],"Ensembl":"ENSG00000134982","Gene description":"APC regulator of WNT signaling pathway","Uniprot":["P25054"],"Chromosome":"5","Position":"112707498-112846239","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"52.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"519.7","Inhibitory neurons":"231.0","Oligodendrocyte precursor cells":"188.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013349","HPA013362"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA013349":"AB_1844913","HPA013362":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"}},{"Gene":"APCDD1","Gene synonym":["B7323"],"Ensembl":"ENSG00000154856","Gene description":"APC down-regulated 1","Uniprot":["Q8J025"],"Chromosome":"18","Position":"10454635-10489949","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"129.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"116.7","Cholangiocytes":"102.0","Endometrial stromal cells":"424.2","Melanocytes":"106.2","Oligodendrocyte precursor cells":"105.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"129.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.39e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.23e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"}},{"Gene":"APCDD1L","Gene synonym":["FLJ90166"],"Ensembl":"ENSG00000198768","Gene description":"APC down-regulated 1 like","Uniprot":["Q8NCL9"],"Chromosome":"20","Position":"58459101-58515399","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"19.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"8.7","Breast myoepithelial cells":"6.2","Fibroblasts":"3.0","Oligodendrocyte precursor cells":"5.8","Pancreatic endocrine cells":"10.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"43.5"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Pancreas - Beta cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067015"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA067015":"AB_2685764"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"}},{"Gene":"APELA","Gene synonym":["ELA","Ende","tdl"],"Ensembl":"ENSG00000248329","Gene description":"Apelin receptor early endogenous ligand","Uniprot":["P0DMC3"],"Chromosome":"4","Position":"164877178-164898965","Protein class":["Predicted secreted proteins"],"Biological process":["Angiogenesis","Differentiation","Gastrulation"],"Molecular function":["Developmental protein","Hormone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"2.2","prostate":"4.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"28.6","Prostatic glandular cells":"11.3","Proximal tubular cells":"37.7","Syncytiotrophoblasts":"34.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"1.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"8.9","testis cancer":"25.1"},"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-4"}},{"Gene":"APH1A","Gene synonym":["APH-1A","CGI-78"],"Ensembl":"ENSG00000117362","Gene description":"Aph-1 homolog A, gamma-secretase subunit","Uniprot":["Q96BI3"],"Chromosome":"1","Position":"150265399-150269580","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Notch signaling pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037272"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037272":"AB_476776"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"}},{"Gene":"APH1B","Gene synonym":["APH-1B","DKFZp564D0372","PSFL"],"Ensembl":"ENSG00000138613","Gene description":"Aph-1 homolog B, gamma-secretase subunit","Uniprot":["Q8WW43"],"Chromosome":"15","Position":"63276018-63309126","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Notch signaling pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"122.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Early spermatids":"1586.5","Late spermatids":"402.1","Spermatocytes":"701.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"107.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"}},{"Gene":"APLF","Gene synonym":["C2orf13","MGC47799","Xip1","ZCCHH1"],"Ensembl":"ENSG00000169621","Gene description":"Aprataxin and PNKP like factor","Uniprot":["Q8IW19"],"Chromosome":"2","Position":"68467572-68655862","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"60.4","Late spermatids":"179.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"7.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"7.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029396","HPA034642","HPA034643"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA029396":"AB_10610285","HPA034642":"AB_2674259","HPA034643":"AB_10602431"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"}},{"Gene":"APLNR","Gene synonym":["AGTRL1","APJ","APJR","FLJ90771"],"Ensembl":"ENSG00000134817","Gene description":"Apelin receptor","Uniprot":["P35414"],"Chromosome":"11","Position":"57233577-57237235","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis","Gastrulation","Host-virus interaction"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"268.8","lymphoid tissue":"101.0","placenta":"88.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Adipocytes":"68.0","Endothelial cells":"69.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"50.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Rhabdoid":"18.7"},"RNA tissue cell type enrichment":["Skin - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025842"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025842":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-3"}},{"Gene":"APLP1","Gene synonym":["APLP"],"Ensembl":"ENSG00000105290","Gene description":"Amyloid beta precursor like protein 1","Uniprot":["P51693"],"Chromosome":"19","Position":"35867899-35879792","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cell adhesion","Endocytosis"],"Molecular function":["Heparin-binding"],"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"1201.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"144.3","Horizontal cells":"87.8","Oligodendrocytes":"435.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"63.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"141.5"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enteroendocrine cells","Kidney - Podocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028970","HPA028971"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6400000","Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA028970":"AB_2672847","HPA028971":"AB_10601334"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.87e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.65e-5"}},{"Gene":"APLP2","Gene synonym":["APPH","APPL2"],"Ensembl":"ENSG00000084234","Gene description":"Amyloid beta precursor like protein 2","Uniprot":["Q06481"],"Chromosome":"11","Position":"130068147-130144811","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["DNA-binding","Protease inhibitor","Serine protease inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"249.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039319"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA039319":"AB_10673141"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.37e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"}},{"Gene":"APMAP","Gene synonym":["BSCv","C20orf3"],"Ensembl":"ENSG00000101474","Gene description":"Adipocyte plasma membrane associated protein","Uniprot":["Q9HDC9"],"Chromosome":"20","Position":"24962925-24992751","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"314.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"322.2","NK-cells":"230.9","Syncytiotrophoblasts":"844.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"680.7","NK-cells":"343.8","T-cells":"367.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Lung - Neutrophil_2","Skin - Sebaceous gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012863","HPA064700"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA012863":"AB_1845683","HPA064700":"AB_2685328"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"}},{"Gene":"APOA2","Gene synonym":[],"Ensembl":"ENSG00000158874","Gene description":"Apolipoprotein A2","Uniprot":["P02652"],"Chromosome":"1","Position":"161222292-161223631","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Host-virus interaction","Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"1388","RNA tissue specific nTPM":{"liver":"36012.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"62","RNA single cell type specific nTPM":{"Hepatocytes":"52487.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"329","RNA cancer specific FPKM":{"liver cancer":"11230.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"liver cancer":"2323.0"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025885","HPA072575"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":115000000000,"Blood concentration - Conc. blood MS [pg\/L]":"92000000000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025885":null,"HPA072575":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"}},{"Gene":"APOBEC1","Gene synonym":["APOBEC-1","BEDP","CDAR1","HEPR"],"Ensembl":"ENSG00000111701","Gene description":"Apolipoprotein B mRNA editing enzyme catalytic subunit 1","Uniprot":["P41238"],"Chromosome":"12","Position":"7649400-7665908","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["mRNA processing"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"25","RNA tissue specific nTPM":{"intestine":"29.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Proximal enterocytes":"165.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"colorectal cancer":"6.2","pancreatic cancer":"6.1","stomach cancer":"3.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.1"},"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"APOC4-APOC2","Gene synonym":[],"Ensembl":"ENSG00000224916","Gene description":"APOC4-APOC2 readthrough (NMD candidate)","Uniprot":[],"Chromosome":"19","Position":"44942238-44949565","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"1258","RNA tissue specific nTPM":{"liver":"2221.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Hepatocytes":"99.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"liver cancer":"9.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055877"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055877":"AB_2682953"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"}},{"Gene":"APOL1","Gene synonym":["APOL"],"Ensembl":"ENSG00000100342","Gene description":"Apolipoprotein L1","Uniprot":["O14791"],"Chromosome":"22","Position":"36253071-36267530","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"220.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"108.5","Endometrial ciliated cells":"115.5","Glandular and luminal cells":"222.6","Hepatocytes":"98.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"337.3"},"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Kidney - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018885","CAB056156"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1640000000,"Blood concentration - Conc. blood MS [pg\/L]":"9200000000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB056156":"AB_2665576","HPA018885":"AB_1844953"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.35e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.43e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.01e-5"}},{"Gene":"APOL6","Gene synonym":["APOL-VI","APOLVI"],"Ensembl":"ENSG00000221963","Gene description":"Apolipoprotein L6","Uniprot":["Q9BWW8"],"Chromosome":"22","Position":"35648446-35668404","Protein class":["Predicted membrane proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"46.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"111.7","NK-cells":"149.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB028574","HPA029165","HPA029167"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB028574":null,"HPA029165":"AB_10670037","HPA029167":"AB_10670832"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.61e-4"}},{"Gene":"APOLD1","Gene synonym":["DKFZP434F0318","FLJ25138"],"Ensembl":"ENSG00000178878","Gene description":"Apolipoprotein L domain containing 1","Uniprot":["Q96LR9"],"Chromosome":"12","Position":"12725917-12829975","Protein class":["Predicted membrane proteins"],"Biological process":["Angiogenesis","Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"124.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"771.9","Endothelial cells":"237.1","Smooth muscle cells":"170.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"24.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"skin cancer":"36.1"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"5.7","olfactory bulb":"20.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052462","HPA058882"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA052462":"AB_2681841","HPA058882":"AB_2683844"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"}},{"Gene":"APOO","Gene synonym":["FAM121B","MGC4825","Mic23","MIC26","MICOS26","My025"],"Ensembl":"ENSG00000184831","Gene description":"Apolipoprotein O","Uniprot":["Q9BUR5"],"Chromosome":"X","Position":"23833353-23907938","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"112.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skin - Eccrine sweat gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003187"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":2210000000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA003187":"AB_1079375"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.77e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-3"}},{"Gene":"APOOL","Gene synonym":["AAIR8193","CXorf33","FAM121A","Mic27","MICOS27","UNQ8193"],"Ensembl":"ENSG00000155008","Gene description":"Apolipoprotein O like","Uniprot":["Q6UXV4"],"Chromosome":"X","Position":"85003877-85093316","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"74.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000612","HPA076210"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA000612":"AB_1078594","HPA076210":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.68e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"}},{"Gene":"APP","Gene synonym":["AD1"],"Ensembl":"ENSG00000142192","Gene description":"Amyloid beta precursor protein","Uniprot":["P05067"],"Chromosome":"21","Position":"25880550-26171128","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Apoptosis","Cell adhesion","Endocytosis","Notch signaling pathway"],"Molecular function":["Heparin-binding","Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Alzheimer disease","Amyloidosis","Disease variant","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"822.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"38.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"38.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000157","HPA001462"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"26000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB000157":"AB_323833","HPA001462":"AB_1078185"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.79e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"}},{"Gene":"AQP1","Gene synonym":["CHIP28","CO"],"Ensembl":"ENSG00000240583","Gene description":"Aquaporin 1 (Colton blood group)","Uniprot":["P29972"],"Chromosome":"7","Position":"30911853-30925517","Protein class":["Blood group antigen proteins","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Blood group antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Adipocytes":"893.4","Alveolar cells type 1":"410.5","Alveolar cells type 2":"395.3","Cholangiocytes":"336.8","Endothelial cells":"684.7","Proximal tubular cells":"239.4","Thymic epithelial cells":"647.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"336.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"49.0"},"RNA tissue cell type enrichment":["Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"medulla oblongata":"5.5","spinal cord":"22.0"},"Antibody":["CAB001707","HPA019206"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"49000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB001707":null,"HPA019206":"AB_1844965"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.52e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"}},{"Gene":"AQP10","Gene synonym":[],"Ensembl":"ENSG00000143595","Gene description":"Aquaporin 10","Uniprot":["Q96PS8"],"Chromosome":"1","Position":"154321090-154325325","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"intestine":"68.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"1.9","Erythroid cells":"1.1","granulocytes":"8.2","Sertoli cells":"2.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.6","Neuroblastoma":"1.2"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062621","HPA065947"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA062621":null,"HPA065947":"AB_2685584"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-3"}},{"Gene":"AQP11","Gene synonym":[],"Ensembl":"ENSG00000178301","Gene description":"Aquaporin 11","Uniprot":["Q8NBQ7"],"Chromosome":"11","Position":"77589391-77610356","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"28.6","liver":"16.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"45.7","Hepatocytes":"37.8","Late spermatids":"64.7","Proximal enterocytes":"33.8","Spermatocytes":"50.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Kidney - Proximal tubular cells","Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077460"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA077460":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.89e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-3"}},{"Gene":"AQP12A","Gene synonym":["AQP12"],"Ensembl":"ENSG00000184945","Gene description":"Aquaporin 12A","Uniprot":["Q8IXF9"],"Chromosome":"2","Position":"240691851-240698483","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"332","RNA tissue specific nTPM":{"pancreas":"129.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042216"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042216":"AB_2677905"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AQP12B","Gene synonym":["INSSA3"],"Ensembl":"ENSG00000185176","Gene description":"Aquaporin 12B","Uniprot":["A6NM10"],"Chromosome":"2","Position":"240676418-240682906","Protein class":["Predicted membrane proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"334","RNA tissue specific nTPM":{"pancreas":"209.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042216"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042216":"AB_2677905"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"AQP2","Gene synonym":[],"Ensembl":"ENSG00000167580","Gene description":"Aquaporin 2","Uniprot":["P41181"],"Chromosome":"12","Position":"49950737-49958878","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Diabetes insipidus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"92","RNA tissue specific nTPM":{"kidney":"386.9","seminal vesicle":"212.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Collecting duct cells":"3264.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"renal cancer":"1.7","stomach cancer":"1.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"1.3"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells (progenitors)","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046834"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046834":"AB_2679830"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"AQP3","Gene synonym":["GIL"],"Ensembl":"ENSG00000165272","Gene description":"Aquaporin 3 (Gill blood group)","Uniprot":["Q92482"],"Chromosome":"9","Position":"33441156-33447596","Protein class":["Blood group antigen proteins","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Transport"],"Molecular function":["Blood group antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"1526.1","skin 1":"581.9","urinary bladder":"688.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"1573.3","Basal squamous epithelial cells":"1021.8","Collecting duct cells":"1086.9","Squamous epithelial cells":"2389.1","Suprabasal keratinocytes":"2174.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"cervical cancer":"319.0","head and neck cancer":"283.7","lung cancer":"146.8","urothelial cancer":"221.3"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"hippocampal formation":"5.3","medulla oblongata":"16.0","pons":"21.0"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"181.7","T-reg":"205.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"T-cells":"205.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"392.4"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014924"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014924":"AB_2669120"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.31e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"}},{"Gene":"AQP4","Gene synonym":["MIWC"],"Ensembl":"ENSG00000171885","Gene description":"Aquaporin 4","Uniprot":["P55087"],"Chromosome":"18","Position":"26852043-26865771","Protein class":["Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"440.5","lung":"114.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Alveolar cells type 1":"427.4","Alveolar cells type 2":"326.1","Astrocytes":"472.6","Muller glia cells":"200.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"22","RNA cancer specific FPKM":{"glioma":"223.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Brain cancer":"3.0","Rhabdoid":"1.7"},"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005079","HPA014784","CAB058689"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"CAB005079":"AB_2274338","CAB058689":"AB_2665579","HPA014784":"AB_1844967"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-8"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"AQP5","Gene synonym":[],"Ensembl":"ENSG00000161798","Gene description":"Aquaporin 5","Uniprot":["P55064"],"Chromosome":"12","Position":"49961872-49965682","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"622.6","testis":"222.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1367.4","Late spermatids":"4326.5","Serous glandular cells":"1041.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"87.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"55.5","Gastric cancer":"19.1"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells (progenitors)","Skin - Eccrine sweat gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065008"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA065008":"AB_2685401"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.75e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-3"}},{"Gene":"AQP6","Gene synonym":["AQP2L"],"Ensembl":"ENSG00000086159","Gene description":"Aquaporin 6","Uniprot":["Q13520"],"Chromosome":"12","Position":"49967194-49977139","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"kidney":"52.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"4.1","Club cells":"1.5","Collecting duct cells":"2.0","Distal tubular cells":"3.1","Ionocytes":"5.6","Oligodendrocyte precursor cells":"1.4","Oligodendrocytes":"1.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"renal cancer":"9.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells (progenitors)","Liver - Hepatocytes","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"cerebellum":"21.0"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015278"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015278":"AB_10600982"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"}},{"Gene":"AQP7","Gene synonym":["AQP7L","AQP9","AQPap"],"Ensembl":"ENSG00000165269","Gene description":"Aquaporin 7","Uniprot":["O14520"],"Chromosome":"9","Position":"33383179-33402682","Protein class":["Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"252.7","breast":"104.9","heart muscle":"108.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"107.2","Cardiomyocytes":"88.1","Early spermatids":"140.2","Proximal enterocytes":"145.2","Proximal tubular cells":"53.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.21e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"}},{"Gene":"AQP8","Gene synonym":[],"Ensembl":"ENSG00000103375","Gene description":"Aquaporin 8","Uniprot":["O94778"],"Chromosome":"16","Position":"25215731-25228932","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"641","RNA tissue specific nTPM":{"intestine":"330.0","pancreas":"1280.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Distal enterocytes":"1439.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"6.4","pancreatic cancer":"15.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Pancreas - Exocrine glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046259"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046259":"AB_10960494"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"}},{"Gene":"AQP9","Gene synonym":["HsT17287","SSC1"],"Ensembl":"ENSG00000103569","Gene description":"Aquaporin 9","Uniprot":["O43315"],"Chromosome":"15","Position":"58138169-58185911","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"liver":"702.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"281.2","Hofbauer cells":"72.6","Kupffer cells":"88.6","Macrophages":"67.8","monocytes":"174.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"30","RNA cancer specific FPKM":{"liver cancer":"132.4"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"14.4"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"20","RNA blood cell specific nTPM":{"neutrophil":"1161.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"granulocytes":"1161.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"lymphoma":"10.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Colon - Neutrophils","Heart muscle - Neutrophils","Liver - Hepatocytes","Lung - Neutrophil_2","Skeletal muscle - Neutrophils","Skin - Keratinocyte (granular)","Stomach - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074762","CAB075684"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB075684":null,"HPA074762":"AB_2732267"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.72e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"}},{"Gene":"AQR","Gene synonym":["fSAP164","IBP160","KIAA0560"],"Ensembl":"ENSG00000021776","Gene description":"Aquarius intron-binding spliceosomal factor","Uniprot":["O60306"],"Chromosome":"15","Position":"34851782-34969742","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Helicase","Hydrolase","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"108.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040624","HPA055647"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA040624":"AB_2677050","HPA055647":"AB_2682874"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"}},{"Gene":"AREG","Gene synonym":["AREGB","SDGF"],"Ensembl":"ENSG00000109321","Gene description":"Amphiregulin","Uniprot":["P15514"],"Chromosome":"4","Position":"74445136-74455005","Protein class":["Cancer-related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Cytokine","Growth factor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"129.9","placenta":"328.8","urinary bladder":"145.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"2244.1","dendritic cells":"3701.1","granulocytes":"3395.6","monocytes":"2360.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"67.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"basophil":"11.0","eosinophil":"11.8","NK-cell":"3.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"11.8","NK-cells":"3.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"525.2"},"RNA tissue cell type enrichment":["Colon - Neutrophils","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008720","CAB023519"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1520000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB023519":"AB_2060673","HPA008720":"AB_1844978"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.61e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.32e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-3"}},{"Gene":"AREL1","Gene synonym":["FIEL1","KIAA0317"],"Ensembl":"ENSG00000119682","Gene description":"Apoptosis resistant E3 ubiquitin protein ligase 1","Uniprot":["O15033"],"Chromosome":"14","Position":"74653437-74713117","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051306"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051306":"AB_2681433"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.67e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"}},{"Gene":"ARHGAP26","Gene synonym":["GRAF","KIAA0621","OPHN1L","OPHN1L1"],"Ensembl":"ENSG00000145819","Gene description":"Rho GTPase activating protein 26","Uniprot":["Q9UNA1"],"Chromosome":"5","Position":"142770377-143229011","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"230.0","Excitatory neurons":"603.2","Inhibitory neurons":"255.6","Late spermatids":"214.1","Microglial cells":"317.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"24.7","NK-cell":"9.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"24.7","NK-cells":"9.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035106","HPA035107"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035106":"AB_2674465","HPA035107":"AB_10669855"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.05e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.95e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.93e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.88e-6"}},{"Gene":"ARHGAP4","Gene synonym":["C1","KIAA0131","p115","RhoGAP4","SrGAP4"],"Ensembl":"ENSG00000089820","Gene description":"Rho GTPase activating protein 4","Uniprot":["P98171"],"Chromosome":"X","Position":"153907367-153934999","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"119.1","lymphoid tissue":"120.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"69.9","dendritic cells":"63.7","Hofbauer cells":"94.3","Kupffer cells":"54.8","Macrophages":"76.4","monocytes":"108.7","NK-cells":"66.2","T-cells":"66.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"95.7","lymphoma":"75.9","Myeloma":"106.0"},"RNA tissue cell type enrichment":["Skeletal muscle - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000301","HPA001012","HPA001083"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA000301":null,"HPA001012":"AB_1078201","HPA001083":"AB_1078199"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.94e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.97e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.31e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"}},{"Gene":"ARHGAP8","Gene synonym":["BPGAP1","FLJ20185"],"Ensembl":"ENSG00000241484","Gene description":"Rho GTPase activating protein 8","Uniprot":["P85298"],"Chromosome":"22","Position":"44752558-44862788","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"28.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"26.8","Ductal cells":"25.3","Exocrine glandular cells":"26.0","Undifferentiated cells":"21.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069694"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069694":"AB_2686173"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"}},{"Gene":"ARHGEF1","Gene synonym":["LBCL2","P115-RHOGEF","SUB1.5"],"Ensembl":"ENSG00000076928","Gene description":"Rho guanine nucleotide exchange factor 1","Uniprot":["Q92888"],"Chromosome":"19","Position":"41883173-41930150","Protein class":["Disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation","Guanine-nucleotide releasing factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"168.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"181.7","T-cells":"156.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009502","HPA012924","HPA060784"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009502":"AB_667785","HPA012924":"AB_1845000","HPA060784":"AB_2684363"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.92e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.36e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"}},{"Gene":"ARHGEF17","Gene synonym":["KIAA0337","p164-RhoGEF","TEM4"],"Ensembl":"ENSG00000110237","Gene description":"Rho guanine nucleotide exchange factor 17","Uniprot":["Q96PE2"],"Chromosome":"11","Position":"73308276-73369388","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"37.3","Endometrial stromal cells":"38.3","Horizontal cells":"40.4","Sertoli cells":"38.7","Smooth muscle cells":"68.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007991"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007991":"AB_1845005"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.27e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-3"}},{"Gene":"ARHGEF2","Gene synonym":["GEF-H1","GEFH1","KIAA0651","Lfc","LFP40","P40"],"Ensembl":"ENSG00000116584","Gene description":"Rho\/Rac guanine nucleotide exchange factor 2","Uniprot":["Q92974"],"Chromosome":"1","Position":"155946851-156007070","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Differentiation","Immunity","Innate immunity","Mitosis","Neurogenesis"],"Molecular function":["Developmental protein","Guanine-nucleotide releasing factor"],"Disease involvement":["Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"99.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Skin - Endothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043437"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043437":"AB_2678481"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.20e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.17e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"}},{"Gene":"ARHGEF28","Gene synonym":["p190RhoGEF","RGNEF","RIP2"],"Ensembl":"ENSG00000214944","Gene description":"Rho guanine nucleotide exchange factor 28","Uniprot":["Q8N1W1"],"Chromosome":"5","Position":"73626158-73941993","Protein class":["Predicted intracellular proteins"],"Biological process":["Differentiation"],"Molecular function":["Guanine-nucleotide releasing factor","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"31.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"72.1","Granulosa cells":"79.0","Mucus glandular cells":"57.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037602"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Microtubules","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA037602":"AB_10672282"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.31e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.91e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.98e-4"}},{"Gene":"ARHGEF7","Gene synonym":["BETA-PIX","COOL1","DKFZp686C12170","DKFZp761K1021","KIAA0142","Nbla10314","P50","P50BP","P85","P85COOL1","P85SPR","PAK3","PIXB"],"Ensembl":"ENSG00000102606","Gene description":"Rho guanine nucleotide exchange factor 7","Uniprot":["Q14155"],"Chromosome":"13","Position":"111114559-111305737","Protein class":["Predicted intracellular proteins"],"Biological process":["Neurogenesis"],"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"276.1","Inhibitory neurons":"185.6","Oligodendrocyte precursor cells":"162.2","Oligodendrocytes":"254.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004744"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004744":"AB_1845332"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.30e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"}},{"Gene":"ARL10","Gene synonym":["ARL10A"],"Ensembl":"ENSG00000175414","Gene description":"ADP ribosylation factor like GTPase 10","Uniprot":["Q8N8L6"],"Chromosome":"5","Position":"176365487-176401865","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"17.2","Inhibitory neurons":"17.8","Oligodendrocyte precursor cells":"25.0","Oligodendrocytes":"19.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047044"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047044":"AB_2679915"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"}},{"Gene":"ARL13B","Gene synonym":["ARL2L1","DKFZp761H079","JBTS8"],"Ensembl":"ENSG00000169379","Gene description":"ADP ribosylation factor like GTPase 13B","Uniprot":["Q3SXY8"],"Chromosome":"3","Position":"93980139-94055678","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Joubert syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"18.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"159.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048926"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Microtubules"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA048926":"AB_2680559"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"}},{"Gene":"ARL6IP1","Gene synonym":["AIP1","ARL6IP","ARMER","KIAA0069","SPG61"],"Ensembl":"ENSG00000170540","Gene description":"ADP ribosylation factor like GTPase 6 interacting protein 1","Uniprot":["Q15041"],"Chromosome":"16","Position":"18791669-18801572","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045307"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA045307":"AB_10961042"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-3"}},{"Gene":"ARL6IP5","Gene synonym":["DERP11","GTRAP3-18","HSPC127","JWA","PRAF3","Yip6b"],"Ensembl":"ENSG00000144746","Gene description":"ADP ribosylation factor like GTPase 6 interacting protein 5","Uniprot":["O75915"],"Chromosome":"3","Position":"69084937-69106092","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015540","CAB019321"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB019321":null,"HPA015540":"AB_1852061"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"}},{"Gene":"ARL6IP6","Gene synonym":["MGC33864"],"Ensembl":"ENSG00000177917","Gene description":"ADP ribosylation factor like GTPase 6 interacting protein 6","Uniprot":["Q8N6S5"],"Chromosome":"2","Position":"152717893-152762396","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"156.9","Extravillous trophoblasts":"139.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"214.0","eosinophil":"161.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"214.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014743"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA014743":"AB_1845030"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"}},{"Gene":"ARMC10","Gene synonym":["MGC3195","SVH"],"Ensembl":"ENSG00000170632","Gene description":"Armadillo repeat containing 10","Uniprot":["Q8N2F6"],"Chromosome":"7","Position":"103074881-103099759","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Growth regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011036","HPA011057"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA011036":"AB_1080139","HPA011057":"AB_1080137"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.90e-6"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"}},{"Gene":"ARMC12","Gene synonym":["C6orf81","FLJ25390"],"Ensembl":"ENSG00000157343","Gene description":"Armadillo repeat containing 12","Uniprot":["Q5T9G4"],"Chromosome":"6","Position":"35737032-35749079","Protein class":["Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"64.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"107","RNA single cell type specific nTPM":{"Early spermatids":"416.4","Late spermatids":"1132.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030895","HPA075457","HPA075777"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA030895":"AB_10602114","HPA075457":null,"HPA075777":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"}},{"Gene":"ARMC5","Gene synonym":["FLJ13063"],"Ensembl":"ENSG00000140691","Gene description":"Armadillo repeat containing 5","Uniprot":["Q96C12"],"Chromosome":"16","Position":"31458080-31467166","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cushing syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041524","HPA063706"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Focal adhesion sites","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Focal adhesion sites"],"Antibody RRID":{"HPA041524":"AB_10796676","HPA063706":"AB_2685098"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.97e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"}},{"Gene":"ARMCX1","Gene synonym":["ALEX1","GASP7"],"Ensembl":"ENSG00000126947","Gene description":"Armadillo repeat containing X-linked 1","Uniprot":["Q9P291"],"Chromosome":"X","Position":"101550547-101554700","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"80.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"7.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"28.4"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000268","HPA005685","CAB020695"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB020695":null,"HPA000268":null,"HPA005685":"AB_10600781"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.32e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"}},{"Gene":"ARMCX2","Gene synonym":["ALEX2","GASP9","KIAA0512"],"Ensembl":"ENSG00000184867","Gene description":"Armadillo repeat containing X-linked 2","Uniprot":["Q7L311"],"Chromosome":"X","Position":"101655281-101659850","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"154.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"50.8","Cardiomyocytes":"42.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"47.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"90.3"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Skin - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005761"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA005761":"AB_10600782"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.45e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.69e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"ARMCX3","Gene synonym":["ALEX3","GASP6"],"Ensembl":"ENSG00000102401","Gene description":"Armadillo repeat containing X-linked 3","Uniprot":["Q9UH62"],"Chromosome":"X","Position":"101622797-101627843","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"88.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000325","HPA000967","HPA001530"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA000325":"AB_1078206","HPA000967":"AB_1078208","HPA001530":"AB_2666349"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"}},{"Gene":"ARMCX6","Gene synonym":["FLJ20811","GASP10"],"Ensembl":"ENSG00000198960","Gene description":"Armadillo repeat containing X-linked 6","Uniprot":["Q7L4S7"],"Chromosome":"X","Position":"101615118-101618001","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"19.3","Gastric mucus-secreting cells":"14.3","Plasma cells":"16.5","Squamous epithelial cells":"28.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043030","HPA048125"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Nuclear membrane"],"Antibody RRID":{"HPA043030":"AB_2678277","HPA048125":"AB_2680275"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"}},{"Gene":"ARMH1","Gene synonym":["C1orf228","MGC33556","NCRNA00082","p40"],"Ensembl":"ENSG00000198520","Gene description":"Armadillo like helical domain containing 1","Uniprot":["Q6PIY5"],"Chromosome":"1","Position":"44674692-44725591","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"8.2","testis":"11.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"71.5","dendritic cells":"68.8","Early spermatids":"50.3","granulocytes":"51.8","Late spermatids":"57.6","Respiratory ciliated cells":"35.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"8.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"3.8"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034769","HPA054980"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA034769":"AB_10670979","HPA054980":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.64e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"}},{"Gene":"ARMH4","Gene synonym":["C14orf37","UT2"],"Ensembl":"ENSG00000139971","Gene description":"Armadillo like helical domain containing 4","Uniprot":["Q86TY3"],"Chromosome":"14","Position":"57999735-58298139","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"12.8","kidney":"8.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"44.9","Excitatory neurons":"36.6","Inhibitory neurons":"36.8","Microglial cells":"31.0","Oligodendrocyte precursor cells":"63.5","Theca cells":"31.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Podocytes","Lung - Fibroblast_2","Testis - Sertoli cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001580","HPA001789"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA001580":"AB_2666366","HPA001789":"AB_1078328"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-6"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-4"}},{"Gene":"ARPP19","Gene synonym":["ARPP-16","ARPP-19","ARPP16","ENSAL"],"Ensembl":"ENSG00000128989","Gene description":"CAMP regulated phosphoprotein 19","Uniprot":["P56211"],"Chromosome":"15","Position":"52547045-52569883","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Protein phosphatase inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"268.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Late spermatids":"3631.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056851"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056851":"AB_2683255"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.72e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"}},{"Gene":"ARRB2","Gene synonym":["ARR2","BARR2","DKFZp686L0365"],"Ensembl":"ENSG00000141480","Gene description":"Arrestin beta 2","Uniprot":["P32121"],"Chromosome":"17","Position":"4710596-4721499","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":["Signal transduction inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"263.6","lymphoid tissue":"168.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"313.9","Kupffer cells":"225.1","Langerhans cells":"205.6","Macrophages":"224.2","monocytes":"307.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Lung - Neutrophil_2","Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075177"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA075177":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.93e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.61e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"}},{"Gene":"ARRDC2","Gene synonym":["CLONE24945","PP2703"],"Ensembl":"ENSG00000105643","Gene description":"Arrestin domain containing 2","Uniprot":["Q8TBH0"],"Chromosome":"19","Position":"18001132-18014102","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"204.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"115.5","B-cells":"69.5","Langerhans cells":"72.8","monocytes":"61.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053788","HPA074216"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053788":"AB_2682262","HPA074216":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.93e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.84e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.91e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.92e-4"}},{"Gene":"ARSF","Gene synonym":[],"Ensembl":"ENSG00000062096","Gene description":"Arylsulfatase F","Uniprot":["P54793"],"Chromosome":"X","Position":"3041471-3112727","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.9","kidney":"7.6","skin 1":"5.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"9.2","Inhibitory neurons":"4.5","Oligodendrocyte precursor cells":"2.4","Proximal tubular cells":"7.1","Serous glandular cells":"4.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000549"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA000549":"AB_1845055"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"}},{"Gene":"ARSH","Gene synonym":[],"Ensembl":"ENSG00000205667","Gene description":"Arylsulfatase family member H","Uniprot":["Q5FYA8"],"Chromosome":"X","Position":"3006546-3034111","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"1.3","Breast myoepithelial cells":"1.3","Cholangiocytes":"1.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"}},{"Gene":"ARSJ","Gene synonym":["FLJ23548"],"Ensembl":"ENSG00000180801","Gene description":"Arylsulfatase family member J","Uniprot":["Q5FYB0"],"Chromosome":"4","Position":"113900284-113979727","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"50.3","Astrocytes":"42.7","Collecting duct cells":"23.6","Excitatory neurons":"26.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036481","HPA036482"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Actin filaments"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA036481":"AB_2675146","HPA036482":"AB_10672356"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.08e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.97e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"}},{"Gene":"ARSL","Gene synonym":["ARSE","CDPX","CDPX1"],"Ensembl":"ENSG00000157399","Gene description":"Arylsulfatase L","Uniprot":["P51690"],"Chromosome":"X","Position":"2934521-2968475","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"36.6","liver":"86.3","pancreas":"105.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"32.1","Enteroendocrine cells":"41.5","Hepatocytes":"65.7","Paneth cells":"47.6","Proximal enterocytes":"48.5","Proximal tubular cells":"78.3","Undifferentiated cells":"58.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"34.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"32.0","liver cancer":"34.8"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060518","HPA070651"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA060518":"AB_2684301","HPA070651":"AB_2732160"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.95e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"}},{"Gene":"ART1","Gene synonym":["ART2","ARTC1","CD296"],"Ensembl":"ENSG00000129744","Gene description":"ADP-ribosyltransferase 1","Uniprot":["P52961"],"Chromosome":"11","Position":"3645128-3664416","Protein class":["CD markers","Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Nucleotidyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"57","RNA tissue specific nTPM":{"skeletal muscle":"47.4","tongue":"36.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"1.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051148"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051148":"AB_2681363"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"ART3","Gene synonym":["ARTC3"],"Ensembl":"ENSG00000156219","Gene description":"ADP-ribosyltransferase 3 (inactive)","Uniprot":["Q13508"],"Chromosome":"4","Position":"76011184-76112802","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Nucleotidyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"heart muscle":"67.3","skeletal muscle":"220.2","testis":"96.4","tongue":"101.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"76.0","Skeletal myocytes":"251.4","Spermatocytes":"256.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"2.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"breast cancer":"11.6","skin cancer":"22.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011268"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"48000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011268":"AB_1845059"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-3"}},{"Gene":"ARTN","Gene synonym":["ENOVIN","EVN","NBN"],"Ensembl":"ENSG00000117407","Gene description":"Artemin","Uniprot":["Q5T4W7"],"Chromosome":"1","Position":"43933320-43937240","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"4.3","Early spermatids":"9.4","Ionocytes":"4.5","Rod photoreceptor cells":"5.4","Smooth muscle cells":"4.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Esophageal cancer":"45.0","head and neck cancer":"55.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"olfactory bulb":"3.3"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"olfactory bulb":"1.0"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.18e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"}},{"Gene":"ARV1","Gene synonym":[],"Ensembl":"ENSG00000173409","Gene description":"ARV1 homolog, fatty acid homeostasis modulator","Uniprot":["Q9H2C2"],"Chromosome":"1","Position":"230978981-231000733","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"103.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035709"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035709":"AB_2674744"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.27e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-3"}},{"Gene":"ASAH1","Gene synonym":["AC","ACDase","ASAH","FLJ21558","PHP32"],"Ensembl":"ENSG00000104763","Gene description":"N-acylsphingosine amidohydrolase 1","Uniprot":["Q13510"],"Chromosome":"8","Position":"18055992-18084998","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"573.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"881.1","Hofbauer cells":"949.7","monocytes":"956.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Skin - Keratinocyte (granular)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005468"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"400000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA005468":"AB_1845062"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.08e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-3"}},{"Gene":"ASAH2","Gene synonym":[],"Ensembl":"ENSG00000188611","Gene description":"N-acylsphingosine amidohydrolase 2","Uniprot":["Q9NR71"],"Chromosome":"10","Position":"50182778-50279720","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"intestine":"81.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"11.5","Muller glia cells":"6.5","Proximal enterocytes":"11.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"8.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061171"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Focal adhesion sites"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2200000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA061171":"AB_2684442"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"}},{"Gene":"ASB11","Gene synonym":["DKFZp779E2460"],"Ensembl":"ENSG00000165192","Gene description":"Ankyrin repeat and SOCS box containing 11","Uniprot":["Q8WXH4"],"Chromosome":"X","Position":"15281697-15315640","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"heart muscle":"33.4","skeletal muscle":"114.7","tongue":"61.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Cardiomyocytes":"15.9","Melanocytes":"12.2","Skeletal myocytes":"14.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"20","RNA cancer specific FPKM":{"melanoma":"2.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"ASB18","Gene synonym":[],"Ensembl":"ENSG00000182177","Gene description":"Ankyrin repeat and SOCS box containing 18","Uniprot":["Q6ZVZ8"],"Chromosome":"2","Position":"236194872-236264409","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"4.8","heart muscle":"7.4","skeletal muscle":"11.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"3.6","Excitatory neurons":"2.8","Skeletal myocytes":"3.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068447"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA068447":"AB_2685991"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ASB5","Gene synonym":[],"Ensembl":"ENSG00000164122","Gene description":"Ankyrin repeat and SOCS box containing 5","Uniprot":["Q8WWX0"],"Chromosome":"4","Position":"176213673-176277571","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skeletal muscle":"217.2","tongue":"67.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Late spermatids":"306.6","Skeletal myocytes":"231.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"1.5","prostate cancer":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bile duct cancer":"15.6","Sarcoma":"25.5"},"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028870"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA028870":"AB_10611679"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.67e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-3"}},{"Gene":"ASGR1","Gene synonym":["CLEC4H1"],"Ensembl":"ENSG00000141505","Gene description":"Asialoglycoprotein receptor 1","Uniprot":["P07306"],"Chromosome":"17","Position":"7173431-7179564","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Endocytosis","Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"41","RNA tissue specific nTPM":{"liver":"1092.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"988.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"90","RNA cancer specific FPKM":{"liver cancer":"131.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"115.2","intermediate monocyte":"55.5","myeloid DC":"41.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"41.2","monocytes":"115.2"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"liver cancer":"83.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"cerebellum":"44.1"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011954","HPA012852"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cell Junctions"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA011954":"AB_1845079","HPA012852":"AB_1845080"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-3"}},{"Gene":"ASGR2","Gene synonym":["CLEC4H2"],"Ensembl":"ENSG00000161944","Gene description":"Asialoglycoprotein receptor 2","Uniprot":["P07307"],"Chromosome":"17","Position":"7101322-7115700","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis","Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"48","RNA tissue specific nTPM":{"liver":"840.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatocytes":"773.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"66","RNA cancer specific FPKM":{"liver cancer":"214.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"classical monocyte":"110.0","myeloid DC":"64.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"51","RNA blood lineage specific nTPM":{"dendritic cells":"64.1","monocytes":"110.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"liver cancer":"103.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Liver - Hepatocytes","Lung - Neutrophil_2"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014899","HPA015998"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Endoplasmic reticulum","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014899":"AB_1845085","HPA015998":"AB_1845084"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-7"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"}},{"Gene":"ASIC1","Gene synonym":["ACCN2","BNaC2","hBNaC2"],"Ensembl":"ENSG00000110881","Gene description":"Acid sensing ion channel subunit 1","Uniprot":["P78348"],"Chromosome":"12","Position":"50057548-50083611","Protein class":["Predicted membrane proteins"],"Biological process":["Calcium transport","Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"24.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"30.4","Inhibitory neurons":"16.0","Oligodendrocyte precursor cells":"62.1","Oligodendrocytes":"10.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"12.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Liver - Hepatic stellate cells","Lung - Fibroblast_2","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058870"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA058870":"AB_2683841"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-5"}},{"Gene":"ASIC2","Gene synonym":["ACCN","ACCN1","ASIC2a","BNaC1","BNC1","hBNaC1","MDEG"],"Ensembl":"ENSG00000108684","Gene description":"Acid sensing ion channel subunit 2","Uniprot":["Q16515"],"Chromosome":"17","Position":"33013087-34174964","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"13.0","cervix":"3.4","endometrium 1":"3.4","retina":"4.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Excitatory neurons":"1756.6","Inhibitory neurons":"653.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"5.4","Neuroblastoma":"1.4"},"RNA tissue cell type enrichment":["Skin - Fibroblast_1","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052112"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052112":"AB_2681733"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"ASIC3","Gene synonym":["ACCN3","DRASIC","TNaC1"],"Ensembl":"ENSG00000213199","Gene description":"Acid sensing ion channel subunit 3","Uniprot":["Q9UHC3"],"Chromosome":"7","Position":"151048292-151052756","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"62.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"3.1","testis cancer":"7.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049155","HPA054805"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA049155":"AB_2680657","HPA054805":"AB_2732588"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"}},{"Gene":"ASIC4","Gene synonym":["ACCN4","BNAC4"],"Ensembl":"ENSG00000072182","Gene description":"Acid sensing ion channel subunit family member 4","Uniprot":["Q96FT7"],"Chromosome":"2","Position":"219514170-219538772","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"10.7","pituitary gland":"22.0","retina":"6.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"211.3","Cone photoreceptor cells":"67.2","Horizontal cells":"35.2","Oligodendrocyte precursor cells":"37.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"38","RNA cancer specific FPKM":{"glioma":"8.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"2.3","Neuroblastoma":"4.3","Rhabdoid":"1.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"73.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036042"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA036042":"AB_10672998"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"}},{"Gene":"ASIC5","Gene synonym":["ACCN5","HINAC","INAC"],"Ensembl":"ENSG00000256394","Gene description":"Acid sensing ion channel subunit family member 5","Uniprot":["Q9NY37"],"Chromosome":"4","Position":"155829729-155866277","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"2.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014903","HPA029444"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014903":"AB_1844498","HPA029444":"AB_10611671"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-5"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"}},{"Gene":"ASPH","Gene synonym":["BAH","CASQ2BP1","HAAH","JCTN"],"Ensembl":"ENSG00000198363","Gene description":"Aspartate beta-hydroxylase","Uniprot":["Q12797"],"Chromosome":"8","Position":"61500556-61714640","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"386.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"355.2","Muller glia cells":"395.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"34.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055161","HPA059303"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA055161":"AB_2682721","HPA059303":"AB_2683973"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.07e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.61e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.75e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.57e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.24e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"}},{"Gene":"ASPHD1","Gene synonym":[],"Ensembl":"ENSG00000174939","Gene description":"Aspartate beta-hydroxylase domain containing 1","Uniprot":["Q5U4P2"],"Chromosome":"16","Position":"29900375-29919864","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"138.6","choroid plexus":"79.3","pituitary gland":"36.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"30.8","Enteroendocrine cells":"36.8","Gastric mucus-secreting cells":"29.8","Horizontal cells":"30.1","Oligodendrocytes":"27.7","Pancreatic endocrine cells":"29.2","Thymic epithelial cells":"73.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enteroendocrine cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045175"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045175":"AB_10959899"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.38e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"}},{"Gene":"ASPHD2","Gene synonym":["FLJ39838"],"Ensembl":"ENSG00000128203","Gene description":"Aspartate beta-hydroxylase domain containing 2","Uniprot":["Q6ICH7"],"Chromosome":"22","Position":"26429260-26445015","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"16.9","skin 1":"11.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"26.2","Excitatory neurons":"13.9","Extravillous trophoblasts":"14.8","Late spermatids":"29.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"5.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"2.4","monocytes":"5.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)","Stomach - Gastric mucous cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000820"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000820":"AB_1078231"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.06e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"}},{"Gene":"ASPM","Gene synonym":["ASP","Calmbp1","FLJ10517","FLJ10549","MCPH5"],"Ensembl":"ENSG00000066279","Gene description":"Assembly factor for spindle microtubules","Uniprot":["Q8IZT6"],"Chromosome":"1","Position":"197084121-197146694","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Calmodulin-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"10.1","lymphoid tissue":"17.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"82.6","Granulosa cells":"119.8","Plasma cells":"55.4","Spermatocytes":"47.8","Spermatogonia":"47.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Mitotic cells (Colon)","Heart muscle - Mitotic cells (Heart)","Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Testis - Spermatocytes","Thyroid - Mitotic cells (Thyroid)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017816"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB017816":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.97e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.41e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.40e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"}},{"Gene":"ASPRV1","Gene synonym":["FLJ25084","SASPase","Taps"],"Ensembl":"ENSG00000244617","Gene description":"Aspartic peptidase retroviral like 1","Uniprot":["Q53RT3"],"Chromosome":"2","Position":"69960089-69962265","Protein class":["Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"25","RNA tissue specific nTPM":{"skin 1":"424.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"3.9","Spermatogonia":"3.4","Suprabasal keratinocytes":"7.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"head and neck cancer":"23.1","melanoma":"35.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"8.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"8.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"4.7"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034809","HPA034810"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA034809":"AB_2674343","HPA034810":"AB_10601456"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"}},{"Gene":"ASPSCR1","Gene synonym":["ASPL","ASPS","TUG","UBXD9","UBXN9"],"Ensembl":"ENSG00000169696","Gene description":"ASPSCR1 tether for SLC2A4, UBX domain containing","Uniprot":["Q9BZE9"],"Chromosome":"17","Position":"81976807-82017406","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"273.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026749"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"HPA026749":"AB_1845114"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.55e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.67e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.26e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"}},{"Gene":"ASTE1","Gene synonym":["HT001"],"Ensembl":"ENSG00000034533","Gene description":"Asteroid homolog 1","Uniprot":["Q2TB18"],"Chromosome":"3","Position":"131013875-131027649","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"52.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037010","HPA037011"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA037010":"AB_10673629","HPA037011":"AB_10696929"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.09e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.34e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.03e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"}},{"Gene":"ASTN1","Gene synonym":["ASTN"],"Ensembl":"ENSG00000152092","Gene description":"Astrotactin 1","Uniprot":["O14525"],"Chromosome":"1","Position":"176857302-177164973","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"14.9","brain":"29.8","retina":"14.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"185.4","Excitatory neurons":"215.5","Inhibitory neurons":"269.0","Oligodendrocyte precursor cells":"268.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"glioma":"15.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"3.2","Neuroblastoma":"4.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enteroendocrine cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074112"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA074112":"AB_2686662"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"}},{"Gene":"ASTN2","Gene synonym":["KIAA0634"],"Ensembl":"ENSG00000148219","Gene description":"Astrotactin 2","Uniprot":["O75129"],"Chromosome":"9","Position":"116423112-117415070","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"39.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"343.5","Excitatory neurons":"364.6","Inhibitory neurons":"989.2","Late spermatids":"233.4","Oligodendrocyte precursor cells":"862.1","Oligodendrocytes":"213.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"15.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Liver - Hepatocytes","Prostate - Prostate glandular cells","Testis - Sertoli cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027035"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA027035":"AB_1845122"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.66e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"}},{"Gene":"ASZ1","Gene synonym":["ALP1","ANKL1","C7orf7","CT1.19","GASZ","Orf3"],"Ensembl":"ENSG00000154438","Gene description":"Ankyrin repeat, SAM and basic leucine zipper domain containing 1","Uniprot":["Q8WWH4"],"Chromosome":"7","Position":"117363222-117428123","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Meiosis","RNA-mediated gene silencing","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"testis":"10.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Spermatocytes":"72.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020558"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA020558":"AB_1845123"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ATAD1","Gene synonym":["FLJ14600","Msp1"],"Ensembl":"ENSG00000138138","Gene description":"ATPase family AAA domain containing 1","Uniprot":["Q8NBU5"],"Chromosome":"10","Position":"87751512-87841361","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Early spermatids":"806.0","Late spermatids":"1918.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037569"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli rim","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoli rim"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA037569":"AB_10672496"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.98e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"}},{"Gene":"ATAD3A","Gene synonym":["FLJ10709"],"Ensembl":"ENSG00000197785","Gene description":"ATPase family AAA domain containing 3A","Uniprot":["Q9NVI7"],"Chromosome":"1","Position":"1512162-1534685","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058968","HPA064867","HPA065305"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"27000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA058968":"AB_2683864","HPA064867":"AB_2685375","HPA065305":"AB_2685459"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.90e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"}},{"Gene":"ATF6","Gene synonym":["ATF6A"],"Ensembl":"ENSG00000118217","Gene description":"Activating transcription factor 6","Uniprot":["P18850"],"Chromosome":"1","Position":"161766298-161977574","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation","Unfolded protein response"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005935"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"46000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA005935":"AB_2667472"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-3"}},{"Gene":"ATF6B","Gene synonym":["CREBL1","G13"],"Ensembl":"ENSG00000213676","Gene description":"Activating transcription factor 6 beta","Uniprot":["Q99941"],"Chromosome":"6","Position":"32115264-32128253","Protein class":["Plasma proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation","Unfolded protein response"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046871"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"46000000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA046871":"AB_10963542"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"}},{"Gene":"ATF7","Gene synonym":["ATFA"],"Ensembl":"ENSG00000170653","Gene description":"Activating transcription factor 7","Uniprot":["P17544"],"Chromosome":"12","Position":"53507856-53626410","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"133.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003384"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA003384":"AB_1078234"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"}},{"Gene":"ATG13","Gene synonym":["KIAA0652"],"Ensembl":"ENSG00000175224","Gene description":"Autophagy related 13","Uniprot":["O75143"],"Chromosome":"11","Position":"46617527-46674818","Protein class":["Cancer-related genes","Predicted intracellular proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039350"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA039350":"AB_10673142"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.59e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"}},{"Gene":"ATG2A","Gene synonym":["KIAA0404"],"Ensembl":"ENSG00000110046","Gene description":"Autophagy related 2A","Uniprot":["Q2TAZ0"],"Chromosome":"11","Position":"64894546-64917211","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":["Autophagy","Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"65.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"16.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"16.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038715"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA038715":"AB_10673474"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.79e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"}},{"Gene":"ATG3","Gene synonym":["APG3L","DKFZp564M1178","FLJ22125","MGC15201","PC3-96"],"Ensembl":"ENSG00000144848","Gene description":"Autophagy related 3","Uniprot":["Q9NT62"],"Chromosome":"3","Position":"112532510-112562046","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":["Autophagy","Protein transport","Transport","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"722.4","Spermatocytes":"311.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037260","HPA040471"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB037260":"AB_1078236","HPA040471":"AB_2677000"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.82e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.35e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"}},{"Gene":"ATG4D","Gene synonym":["APG4-D","APG4D","AUTL4"],"Ensembl":"ENSG00000130734","Gene description":"Autophagy related 4D cysteine peptidase","Uniprot":["Q86TL0"],"Chromosome":"19","Position":"10543895-10553418","Protein class":["Enzymes","Predicted intracellular proteins","Transporters"],"Biological process":["Apoptosis","Autophagy","Protein transport","Transport","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"98.4","Early spermatids":"108.5","Proximal enterocytes":"106.3","Spermatocytes":"84.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067683"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA067683":"AB_2685886"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.18e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.95e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.39e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.03e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-3"}},{"Gene":"ATG9A","Gene synonym":["APG9L1","FLJ22169"],"Ensembl":"ENSG00000198925","Gene description":"Autophagy related 9A","Uniprot":["Q7Z3C6"],"Chromosome":"2","Position":"219219380-219229717","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Autophagy","Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"12.3","Excitatory neurons":"15.0","Inhibitory neurons":"13.8","Oligodendrocyte precursor cells":"9.1","Oligodendrocytes":"11.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059551"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059551":"AB_2684060"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.18e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"}},{"Gene":"ATG9B","Gene synonym":["APG9L2","FLJ14885","NOS3AS","SONE"],"Ensembl":"ENSG00000181652","Gene description":"Autophagy related 9B","Uniprot":["Q674R7"],"Chromosome":"7","Position":"151012209-151024499","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy","Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"8.3","skin 1":"11.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"58.2","Endometrial ciliated cells":"28.6","Late spermatids":"27.0","Respiratory ciliated cells":"23.9","Syncytiotrophoblasts":"149.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"6.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"8.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"8.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Lung - Respiratory ciliated cells","Skin - Keratinocyte (granular)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"}},{"Gene":"ATIC","Gene synonym":["AICARFT","IMPCHASE","PURH"],"Ensembl":"ENSG00000138363","Gene description":"5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase\/IMP cyclohydrolase","Uniprot":["P31939"],"Chromosome":"2","Position":"215311956-215349773","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Purine biosynthesis"],"Molecular function":["Hydrolase","Multifunctional enzyme","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"181.6","Extravillous trophoblasts":"165.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013462","HPA021012"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3900000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB013462":null,"HPA021012":"AB_1845169"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.77e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"}},{"Gene":"ATL1","Gene synonym":["AD-FSP","FSP1","SPG3","SPG3A"],"Ensembl":"ENSG00000198513","Gene description":"Atlastin GTPase 1","Uniprot":["Q8WXF7"],"Chromosome":"14","Position":"50532509-50634017","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"42.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"136.7","Inhibitory neurons":"93.3","Oligodendrocyte precursor cells":"78.0","Oligodendrocytes":"129.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"22.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"22.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"16.3"},"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Testis - Early spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027550"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027550":"AB_10600983"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"}},{"Gene":"ATL2","Gene synonym":["ARL6IP2"],"Ensembl":"ENSG00000119787","Gene description":"Atlastin GTPase 2","Uniprot":["Q8NHH9"],"Chromosome":"2","Position":"38293954-38377285","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029108","HPA075302"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA029108":"AB_10670557","HPA075302":"AB_2732289"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.51e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"}},{"Gene":"ATL3","Gene synonym":["DKFZP564J0863"],"Ensembl":"ENSG00000184743","Gene description":"Atlastin GTPase 3","Uniprot":["Q6DD88"],"Chromosome":"11","Position":"63624087-63671921","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"751.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065702","HPA076616"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA065702":"AB_2685536","HPA076616":"AB_2732318"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"}},{"Gene":"ATM","Gene synonym":["ATA","ATC","ATD","ATDC","TEL1","TELO1"],"Ensembl":"ENSG00000149311","Gene description":"ATM serine\/threonine kinase","Uniprot":["Q13315"],"Chromosome":"11","Position":"108222832-108369102","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"275.2","Oligodendrocytes":"205.4","Rod photoreceptor cells":"228.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000102","HPA067142"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB000102":null,"HPA067142":"AB_2685789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"}},{"Gene":"ATP10A","Gene synonym":["ATP10C","ATPVA","ATPVC","KIAA0566"],"Ensembl":"ENSG00000206190","Gene description":"ATPase phospholipid transporting 10A (putative)","Uniprot":["O60312"],"Chromosome":"15","Position":"25677271-25865184","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"15.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Alveolar cells type 1":"92.4","Microglial cells":"210.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"7.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Smooth muscle cells","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041496","HPA042509"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041496":"AB_2677513","HPA042509":"AB_2678032"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.60e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"}},{"Gene":"ATP10B","Gene synonym":["ATPVB","FLJ21477","KIAA0715"],"Ensembl":"ENSG00000118322","Gene description":"ATPase phospholipid transporting 10B (putative)","Uniprot":["O94823"],"Chromosome":"5","Position":"160563120-160852214","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.1","gallbladder":"16.6","intestine":"45.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"96.7","Oligodendrocyte precursor cells":"280.6","Oligodendrocytes":"396.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"19.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"10.3","colorectal cancer":"14.4"},"RNA tissue cell type enrichment":["Breast - Plasma cells","Colon - Colon enterocytes","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034574"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034574":"AB_10669992"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"}},{"Gene":"ATP10D","Gene synonym":["ATPVD","KIAA1487"],"Ensembl":"ENSG00000145246","Gene description":"ATPase phospholipid transporting 10D (putative)","Uniprot":["Q9P241"],"Chromosome":"4","Position":"47485275-47593486","Protein class":["Enzymes","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"206.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"basophil":"84.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"granulocytes":"84.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050808"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA050808":"AB_2681242"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.00e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"}},{"Gene":"ATP11A","Gene synonym":["ATPIH","ATPIS","KIAA1021"],"Ensembl":"ENSG00000068650","Gene description":"ATPase phospholipid transporting 11A","Uniprot":["P98196"],"Chromosome":"13","Position":"112690329-112887168","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"209.9","Alveolar cells type 2":"207.5","Glandular and luminal cells":"152.7","Oligodendrocytes":"130.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Prostate - Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035583","HPA035584"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA035583":"AB_10671106","HPA035584":"AB_10672096"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-3"}},{"Gene":"ATP11B","Gene synonym":["ATPIF","ATPIR","KIAA0956"],"Ensembl":"ENSG00000058063","Gene description":"ATPase phospholipid transporting 11B (putative)","Uniprot":["Q9Y2G3"],"Chromosome":"3","Position":"182793503-182921629","Protein class":["Enzymes","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"125.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036237","HPA036238"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Centriolar satellite","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036237":"AB_10673123","HPA036238":"AB_10670792"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.44e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"}},{"Gene":"ATP11C","Gene synonym":["ATPIG","ATPIQ"],"Ensembl":"ENSG00000101974","Gene description":"ATPase phospholipid transporting 11C","Uniprot":["Q8NB49"],"Chromosome":"X","Position":"139726346-139945276","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"49.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"60.0","Spermatocytes":"69.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"15.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Liver - Hepatocytes","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030830"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030830":"AB_10601336"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"}},{"Gene":"ATP12A","Gene synonym":["ATP1AL1","H-K-ATPase","HK"],"Ensembl":"ENSG00000075673","Gene description":"ATPase H+\/K+ transporting non-gastric alpha2 subunit","Uniprot":["P54707"],"Chromosome":"13","Position":"24680408-24712472","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Potassium transport","Sodium transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"esophagus":"11.2","kidney":"5.4","lymphoid tissue":"14.8","placenta":"5.6","skin 1":"6.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Basal respiratory cells":"172.6","Club cells":"59.4","Ionocytes":"216.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"12.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"testis cancer":"4.8"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039526"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane","Actin filaments"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA039526":"AB_10673534"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"}},{"Gene":"ATP13A1","Gene synonym":["ATP13A","CGI-152","FLJ31858","KIAA1825"],"Ensembl":"ENSG00000105726","Gene description":"ATPase 13A1","Uniprot":["Q9HD20"],"Chromosome":"19","Position":"19645198-19663676","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"59.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031798","HPA049717"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA031798":"AB_2674048","HPA049717":"AB_2680858"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.51e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"}},{"Gene":"ATP13A2","Gene synonym":["CLN12","HSA9947","PARK9"],"Ensembl":"ENSG00000159363","Gene description":"ATPase cation transporting 13A2","Uniprot":["Q9NQ11"],"Chromosome":"1","Position":"16985958-17011928","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuronal ceroid lipofuscinosis","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"112.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"68.5","Horizontal cells":"106.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"plasmacytoid DC":"20.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"20.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037038","CAB037111","HPA050910","HPA054717"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037038":"AB_1840715","CAB037111":"AB_1840714","HPA050910":"AB_2681269","HPA054717":"AB_2682583"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.33e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-3"}},{"Gene":"ATP13A3","Gene synonym":["AFURS1"],"Ensembl":"ENSG00000133657","Gene description":"ATPase 13A3","Uniprot":["Q9H7F0"],"Chromosome":"3","Position":"194402672-194498364","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"524.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029471"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA029471":"AB_10600784"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"}},{"Gene":"ATP13A4","Gene synonym":["DKFZp761I1011","FLJ37958"],"Ensembl":"ENSG00000127249","Gene description":"ATPase 13A4","Uniprot":["Q4VNC1"],"Chromosome":"3","Position":"193398967-193593111","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"64.5","parathyroid gland":"58.4","thyroid gland":"51.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"135.7","Alveolar cells type 2":"71.2","Astrocytes":"396.7","Oligodendrocyte precursor cells":"156.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"23.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"1.9","Gastric cancer":"1.8"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.91e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"}},{"Gene":"ATP13A5","Gene synonym":["FLJ16025"],"Ensembl":"ENSG00000187527","Gene description":"ATPase 13A5","Uniprot":["Q4VNC0"],"Chromosome":"3","Position":"193274789-193378820","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"breast":"17.3","choroid plexus":"38.5","salivary gland":"11.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"36.7","Oligodendrocyte precursor cells":"25.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"1.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Brain cancer":"1.9","breast cancer":"3.4","Esophageal cancer":"1.0"},"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031771","HPA031772","HPA031774"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA031771":"AB_2674038","HPA031772":null,"HPA031774":"AB_2674039"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-4"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"ATP1A1","Gene synonym":[],"Ensembl":"ENSG00000163399","Gene description":"ATPase Na+\/K+ transporting subunit alpha 1","Uniprot":["P05023"],"Chromosome":"1","Position":"116372668-116410261","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Epilepsy","FDA approved drug targets","Intellectual disability","Neurodegeneration","Neuropathy","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"1482.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"1731.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018702","CAB069993"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"420000","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB018702":"AB_626713","CAB069993":"AB_2060979"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.42e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.98e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.01e-4"}},{"Gene":"ATP1A2","Gene synonym":["FHM2","MHP2"],"Ensembl":"ENSG00000018625","Gene description":"ATPase Na+\/K+ transporting subunit alpha 2","Uniprot":["P50993"],"Chromosome":"1","Position":"160115759-160143591","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"515.9","skeletal muscle":"882.2","tongue":"478.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"499.8","Cardiomyocytes":"193.5","Microglial cells":"137.7","Muller glia cells":"89.2","Oligodendrocyte precursor cells":"90.0","Schwann cells":"163.1","Skeletal myocytes":"302.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"glioma":"91.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"1.8","testis cancer":"2.0","thyroid cancer":"1.7","Uterine cancer":"1.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Prostate - Smooth muscle cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022230"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022230":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-3"}},{"Gene":"ATP1A3","Gene synonym":["DYT12"],"Ensembl":"ENSG00000105409","Gene description":"ATPase Na+\/K+ transporting subunit alpha 3","Uniprot":["P13637"],"Chromosome":"19","Position":"41966582-41997497","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Deafness","Disease variant","Dystonia","Epilepsy","Intellectual disability","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"645.2","heart muscle":"157.7","retina":"292.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"399.4","Cone photoreceptor cells":"249.9","Horizontal cells":"323.6","Inhibitory neurons":"116.4","Late spermatids":"97.3","Rod photoreceptor cells":"250.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"21.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"66.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033630","HPA045367","HPA056446"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033630":"AB_781528","HPA045367":"AB_2679297","HPA056446":"AB_2683136"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.44e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.15e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"}},{"Gene":"ATP1A4","Gene synonym":["ATP1AL2"],"Ensembl":"ENSG00000132681","Gene description":"ATPase Na+\/K+ transporting subunit alpha 4","Uniprot":["Q13733"],"Chromosome":"1","Position":"160151586-160186980","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"6.3","testis":"16.3","urinary bladder":"5.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"27.2","Early spermatids":"100.6","Extravillous trophoblasts":"15.6","Late spermatids":"14.6","Syncytiotrophoblasts":"44.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"breast cancer":"0.8","urothelial cancer":"1.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bladder cancer":"2.7","lymphoma":"1.9","testis cancer":"1.7"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.20e-4"}},{"Gene":"ATP1B1","Gene synonym":["ATP1B"],"Ensembl":"ENSG00000143153","Gene description":"ATPase Na+\/K+ transporting subunit beta 1","Uniprot":["P05026"],"Chromosome":"1","Position":"169105697-169132722","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Immunity","Innate immunity","Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"1337.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"1563.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"13.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 2","Skin - Eccrine sweat gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012911"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012911":"AB_1845173"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"}},{"Gene":"ATP1B2","Gene synonym":["AMOG"],"Ensembl":"ENSG00000129244","Gene description":"ATPase Na+\/K+ transporting subunit beta 2","Uniprot":["P14415"],"Chromosome":"17","Position":"7646627-7657770","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"395.1","retina":"614.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"200.9","Bipolar cells":"299.8","Cone photoreceptor cells":"463.6","Muller glia cells":"269.6","Rod photoreceptor cells":"208.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"glioma":"200.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"5.7"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010698"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010698":"AB_1845174"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.17e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"}},{"Gene":"ATP1B3","Gene synonym":["CD298","FLJ29027"],"Ensembl":"ENSG00000069849","Gene description":"ATPase Na+\/K+ transporting subunit beta 3","Uniprot":["P54709"],"Chromosome":"3","Position":"141876124-141926549","Protein class":["CD markers","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"982.1","Late spermatids":"1008.8","monocytes":"1220.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020697","HPA048963"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"33000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB020697":null,"HPA048963":"AB_2680574"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.19e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.32e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"}},{"Gene":"ATP1B4","Gene synonym":[],"Ensembl":"ENSG00000101892","Gene description":"ATPase Na+\/K+ transporting family member beta 4","Uniprot":["Q9UN42"],"Chromosome":"X","Position":"120362085-120383249","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"skeletal muscle":"55.7","tongue":"21.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"44","RNA single cell type specific nTPM":{"Skeletal myocytes":"72.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ATP2A1","Gene synonym":["ATP2A","SERCA1"],"Ensembl":"ENSG00000196296","Gene description":"ATPase sarcoplasmic\/endoplasmic reticulum Ca2+ transporting 1","Uniprot":["O14983"],"Chromosome":"16","Position":"28878405-28904466","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"85","RNA tissue specific nTPM":{"skeletal muscle":"8241.7","tongue":"3199.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"113","RNA single cell type specific nTPM":{"Skeletal myocytes":"637.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"4.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"8","RNA mouse brain regional specific nTPM":{"thalamus":"13.1"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"1.3","cerebral cortex":"1.4","hippocampal formation":"1.2"},"Antibody":["CAB002310","CAB032706","HPA066701"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2800000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB002310":"AB_564139","CAB032706":"AB_2061286","HPA066701":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"}},{"Gene":"ATP2A2","Gene synonym":["ATP2B","DAR","SERCA2"],"Ensembl":"ENSG00000174437","Gene description":"ATPase sarcoplasmic\/endoplasmic reticulum Ca2+ transporting 2","Uniprot":["P16615"],"Chromosome":"12","Position":"110280756-110351093","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"heart muscle":"1005.8","skeletal muscle":"2856.8","tongue":"2768.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"1857.7","Skeletal myocytes":"487.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062605"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2500000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062605":"AB_2684805"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"}},{"Gene":"ATP2A3","Gene synonym":["SERCA3"],"Ensembl":"ENSG00000074370","Gene description":"ATPase sarcoplasmic\/endoplasmic reticulum Ca2+ transporting 3","Uniprot":["Q93084"],"Chromosome":"17","Position":"3923870-3964464","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"101.5","salivary gland":"185.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"78.8","dendritic cells":"72.1","Distal enterocytes":"108.8","Enteroendocrine cells":"74.9","Gastric mucus-secreting cells":"119.2","Intestinal goblet cells":"130.5","Plasma cells":"86.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"129.6","lymphoma":"112.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - T-cells","Liver - T-cells","Skin - Eccrine sweat gland cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"15","RNA mouse brain regional specific nTPM":{"cerebellum":"67.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007180","CAB010882"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5400000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010882":"AB_258368","HPA007180":"AB_1845177"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.69e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.51e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"}},{"Gene":"ATP2B1","Gene synonym":["PMCA1"],"Ensembl":"ENSG00000070961","Gene description":"ATPase plasma membrane Ca2+ transporting 1","Uniprot":["P20020"],"Chromosome":"12","Position":"89588049-89709300","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calmodulin-binding","Translocase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"106.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"770.2","Langerhans cells":"527.6","monocytes":"496.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005605","HPA011166","HPA012945"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB005605":"AB_2061563","HPA011166":"AB_1855484","HPA012945":"AB_1855483"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.74e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"}},{"Gene":"ATP2B2","Gene synonym":["PMCA2"],"Ensembl":"ENSG00000157087","Gene description":"ATPase plasma membrane Ca2+ transporting 2","Uniprot":["Q01814"],"Chromosome":"3","Position":"10324023-10708007","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calmodulin-binding","Translocase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"104.0","choroid plexus":"43.0","salivary gland":"33.2","skeletal muscle":"37.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"113.9","Bipolar cells":"82.1","Excitatory neurons":"318.7","Horizontal cells":"89.1","Inhibitory neurons":"225.4","Oligodendrocyte precursor cells":"55.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"7.7"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"104.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"2.6","Neuroblastoma":"3.3"},"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005606"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB005606":"AB_2243199"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-3"}},{"Gene":"ATP2B3","Gene synonym":["CFAP39","CLA2","PMCA3","SCAX1"],"Ensembl":"ENSG00000067842","Gene description":"ATPase plasma membrane Ca2+ transporting 3","Uniprot":["Q16720"],"Chromosome":"X","Position":"153517676-153582939","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calmodulin-binding","Translocase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"choroid plexus":"187.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"7.0","Excitatory neurons":"23.3","Extravillous trophoblasts":"12.9","Horizontal cells":"23.1","Inhibitory neurons":"29.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"4.3","Neuroblastoma":"8.8"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001583"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001583":"AB_1079641"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"}},{"Gene":"ATP2B4","Gene synonym":["ATP2B2","MXRA1","PMCA4"],"Ensembl":"ENSG00000058668","Gene description":"ATPase plasma membrane Ca2+ transporting 4","Uniprot":["P23634"],"Chromosome":"1","Position":"203626787-203744081","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calmodulin-binding","Translocase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"smooth muscle":"175.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"171.9","Oligodendrocyte precursor cells":"190.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"testis cancer":"222.1"},"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Prostate - Smooth muscle cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016118","HPA040431"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB016118":"AB_2061729","HPA040431":"AB_2676980"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"}},{"Gene":"ATP2C1","Gene synonym":["ATP2C1A","BCPM","KIAA1347","PMR1","SPCA1"],"Ensembl":"ENSG00000017260","Gene description":"ATPase secretory pathway Ca2+ transporting 1","Uniprot":["P98194"],"Chromosome":"3","Position":"130850595-131016712","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"169.9","Prostatic glandular cells":"191.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010207","HPA035116","HPA069684"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB010207":"AB_2061744","HPA035116":"AB_10673106","HPA069684":"AB_2686169"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.06e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"}},{"Gene":"ATP2C2","Gene synonym":["KIAA0703","SPCA2"],"Ensembl":"ENSG00000064270","Gene description":"ATPase secretory pathway Ca2+ transporting 2","Uniprot":["O75185"],"Chromosome":"16","Position":"84368527-84464187","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"37.4","skin 1":"26.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"47.1","Enteroendocrine cells":"43.3","Intestinal goblet cells":"68.6","Ionocytes":"64.7","Oligodendrocyte precursor cells":"56.3","Respiratory ciliated cells":"61.3","Undifferentiated cells":"64.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"11.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"23.8"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Colon - Colon enterocytes","Lung - Alveolar cells type 2","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052262","HPA075812"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Plasma membrane","Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA052262":"AB_2681776","HPA075812":"AB_2686765"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.20e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"}},{"Gene":"ATP4A","Gene synonym":["ATP6A"],"Ensembl":"ENSG00000105675","Gene description":"ATPase H+\/K+ transporting subunit alpha","Uniprot":["P20648"],"Chromosome":"19","Position":"35550031-35563658","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Potassium transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"83","RNA tissue specific nTPM":{"stomach 1":"841.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"62.6","Late spermatids":"20.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"21","RNA cancer specific FPKM":{"stomach cancer":"5.4"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039154","HPA076684"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039154":"AB_10672772","HPA076684":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"}},{"Gene":"ATP4B","Gene synonym":["ATP6B"],"Ensembl":"ENSG00000186009","Gene description":"ATPase H+\/K+ transporting subunit beta","Uniprot":["P51164"],"Chromosome":"13","Position":"113648804-113658198","Protein class":["FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Hydrogen ion transport","Ion transport","Potassium transport","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"305","RNA tissue specific nTPM":{"stomach 1":"1096.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"167","RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"168.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"stomach cancer":"8.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045400","HPA052649"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA045400":"AB_2679314","HPA052649":"AB_2681900"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"ATP5MC1","Gene synonym":["ATP5G","ATP5G1"],"Ensembl":"ENSG00000159199","Gene description":"ATP synthase membrane subunit c locus 1","Uniprot":["P05496"],"Chromosome":"17","Position":"48892765-48895871","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"1296.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1936.8","Distal tubular cells":"1380.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.88e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"}},{"Gene":"ATP5MC2","Gene synonym":["ATP5G2"],"Ensembl":"ENSG00000135390","Gene description":"ATP synthase membrane subunit c locus 2","Uniprot":["Q06055"],"Chromosome":"12","Position":"53632726-53677408","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051469"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051469":"AB_2681496"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"}},{"Gene":"ATP5MC3","Gene synonym":["ATP5G3"],"Ensembl":"ENSG00000154518","Gene description":"ATP synthase membrane subunit c locus 3","Uniprot":["P48201"],"Chromosome":"2","Position":"175176258-175181710","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"1214.0","tongue":"1088.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"2356.3","Distal tubular cells":"2040.0","Proximal tubular cells":"1937.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.90e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.01e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.31e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"}},{"Gene":"ATP5MD","Gene synonym":["bA792D24.4","DAPIT","MGC14697","USMG5"],"Ensembl":"ENSG00000173915","Gene description":"ATP synthase membrane subunit DAPIT","Uniprot":["Q96IX5"],"Chromosome":"10","Position":"103389041-103396492","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"4842.3","Hepatocytes":"2211.0","Proximal tubular cells":"2198.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044798"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA044798":"AB_2679091"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"}},{"Gene":"ATP6AP1","Gene synonym":["16A","Ac45","ATP6IP1","ATP6S1","CF2","ORF","VATPS1","XAP-3","XAP3"],"Ensembl":"ENSG00000071553","Gene description":"ATPase H+ transporting accessory protein 1","Uniprot":["Q15904"],"Chromosome":"X","Position":"154428633-154436516","Protein class":["Disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Lung - Macrophages","Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015218"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"700000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015218":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.40e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.94e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.83e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.26e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"}},{"Gene":"ATP6AP2","Gene synonym":["APT6M8-9","ATP6IP2","ATP6M8-9","M8-9","PRR","RENR"],"Ensembl":"ENSG00000182220","Gene description":"ATPase H+ transporting accessory protein 2","Uniprot":["O75787"],"Chromosome":"X","Position":"40579372-40606848","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant","Epilepsy","Intellectual disability","Neurodegeneration","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"parathyroid gland":"765.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"665.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003156"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003156":"AB_1078245"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.01e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"}},{"Gene":"ATP6V0A1","Gene synonym":["a1","ATP6N1","ATP6N1A","Stv1","Vph1","VPP1"],"Ensembl":"ENSG00000033627","Gene description":"ATPase H+ transporting V0 subunit a1","Uniprot":["Q93050"],"Chromosome":"17","Position":"42458844-42522582","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"130.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"427.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022144"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Golgi apparatus","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Nuclear speckles","Cytosol"],"Antibody RRID":{"HPA022144":"AB_1845189"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.05e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.28e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.90e-4"}},{"Gene":"ATP6V0A2","Gene synonym":["a2","ATP6a2","ATP6N1D","J6B7","Stv1","TJ6","TJ6M","TJ6s","Vph1"],"Ensembl":"ENSG00000185344","Gene description":"ATPase H+ transporting V0 subunit a2","Uniprot":["Q9Y487"],"Chromosome":"12","Position":"123712353-123761755","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"122.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"13.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044279"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Focal adhesion sites"],"Antibody RRID":{"HPA044279":"AB_10961274"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"}},{"Gene":"ATP6V0A4","Gene synonym":["a4","ATP6N1B","ATP6N2","RDRTA2","RTA1C","RTADR","Stv1","Vph1","VPP2"],"Ensembl":"ENSG00000105929","Gene description":"ATPase H+ transporting V0 subunit a4","Uniprot":["Q9HBG4"],"Chromosome":"7","Position":"138706294-138799560","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"kidney":"63.6","salivary gland":"78.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"19.7","Cytotrophoblasts":"13.6","Distal tubular cells":"18.7","Ionocytes":"11.6","Melanocytes":"8.7","Salivary duct cells":"24.8","Serous glandular cells":"11.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"renal cancer":"25.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"9.9","Gastric cancer":"11.2"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells (progenitors)","Kidney - Intercalated cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018029","HPA064555"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA018029":"AB_1845190","HPA064555":"AB_2685284"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"}},{"Gene":"ATP6V0B","Gene synonym":["ATP6F","HATPL","VMA16"],"Ensembl":"ENSG00000117410","Gene description":"ATPase H+ transporting V0 subunit b","Uniprot":["Q99437"],"Chromosome":"1","Position":"43974487-43978295","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"862.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2268.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"769.4","granulocytes":"2268.9","monocytes":"1046.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044281"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA044281":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.79e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.24e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.62e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.87e-4"}},{"Gene":"ATP6V0C","Gene synonym":["ATP6C","ATP6L","ATPL","VATL","Vma3"],"Ensembl":"ENSG00000185883","Gene description":"ATPase H+ transporting V0 subunit c","Uniprot":["P27449"],"Chromosome":"16","Position":"2513952-2520218","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction","Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"113.0","Basal squamous epithelial cells":"337.5","Gastric mucus-secreting cells":"127.6","Inhibitory neurons":"104.7","Macrophages":"108.2","Plasma cells":"185.5","Squamous epithelial cells":"389.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065100"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA065100":"AB_2685421"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.07e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"}},{"Gene":"ATP6V0D1","Gene synonym":["ATP6D","ATP6DV","P39","VATX","Vma6","VPATPD"],"Ensembl":"ENSG00000159720","Gene description":"ATPase H+ transporting V0 subunit d1","Uniprot":["P61421"],"Chromosome":"16","Position":"67438014-67481181","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":["Cilium biogenesis\/degradation","Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"387.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Stomach - Macrophages","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016938"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016938":"AB_1845191"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.20e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.76e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-3"}},{"Gene":"ATP6V0E1","Gene synonym":["ATP6H","ATP6V0E","M9.2"],"Ensembl":"ENSG00000113732","Gene description":"ATPase H+ transporting V0 subunit e1","Uniprot":["O15342"],"Chromosome":"5","Position":"172983771-173035445","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Macrophages","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"}},{"Gene":"ATP6V0E2","Gene synonym":["ATP6V0E2L","C7orf32"],"Ensembl":"ENSG00000171130","Gene description":"ATPase H+ transporting V0 subunit e2","Uniprot":["Q8NHE4"],"Chromosome":"7","Position":"149872968-149891204","Protein class":["Predicted membrane proteins"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"328.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"119.9","Cone photoreceptor cells":"106.8","Horizontal cells":"113.4","Muller glia cells":"160.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"89.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.80e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.26e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-3"}},{"Gene":"ATP6V1C2","Gene synonym":["ATP6C2","VMA5"],"Ensembl":"ENSG00000143882","Gene description":"ATPase H+ transporting V1 subunit C2","Uniprot":["Q8NEY4"],"Chromosome":"2","Position":"10721100-10785110","Protein class":["Metabolic proteins","Predicted intracellular proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"80.3","salivary gland":"103.2","skin 1":"87.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"149.4","Distal tubular cells":"52.9","Glandular and luminal cells":"70.8","Salivary duct cells":"84.0","Syncytiotrophoblasts":"175.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Kidney - Intercalated cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034734","HPA067305"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA034734":"AB_2674305","HPA067305":"AB_2732763"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"}},{"Gene":"ATP6V1F","Gene synonym":["ATP6S14","VATF","Vma7"],"Ensembl":"ENSG00000128524","Gene description":"ATPase H+ transporting V1 subunit F","Uniprot":["Q16864"],"Chromosome":"7","Position":"128862856-128865847","Protein class":["Metabolic proteins","Predicted intracellular proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"1091.5","Hofbauer cells":"1165.7","Late spermatids":"917.7","Proximal tubular cells":"1020.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Lung - Macrophages","Skin - Keratinocyte (other)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009529","HPA048700","HPA062011"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"26000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009529":"AB_2290237","HPA048700":"AB_2680498","HPA062011":"AB_2684656"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"}},{"Gene":"ATP7A","Gene synonym":["MNK"],"Ensembl":"ENSG00000165240","Gene description":"ATPase copper transporting alpha","Uniprot":["Q04656"],"Chromosome":"X","Position":"77910656-78050395","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Copper transport","Ion transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012887","HPA048107"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA012887":"AB_1845205","HPA048107":"AB_2680266"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"}},{"Gene":"ATP7B","Gene synonym":["WND"],"Ensembl":"ENSG00000123191","Gene description":"ATPase copper transporting beta","Uniprot":["P35670"],"Chromosome":"13","Position":"51930436-52012125","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Copper transport","Ion transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"41.6","Late spermatids":"85.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009137","HPA013187"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA009137":"AB_2668214","HPA013187":"AB_1845206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"}},{"Gene":"ATP8A1","Gene synonym":["ATPIA"],"Ensembl":"ENSG00000124406","Gene description":"ATPase phospholipid transporting 8A1","Uniprot":["Q9Y2Q0"],"Chromosome":"4","Position":"42408373-42657105","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"84.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"291.7","Inhibitory neurons":"250.0","Oligodendrocytes":"1149.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"13.5"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"white matter":"84.5"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"17.6"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skeletal muscle - Skeletal myocytes","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052935"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA052935":"AB_2681992"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.54e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"}},{"Gene":"ATP8A2","Gene synonym":["ATPIB","ML-1"],"Ensembl":"ENSG00000132932","Gene description":"ATPase phospholipid transporting 8A2","Uniprot":["Q9NTI2"],"Chromosome":"13","Position":"25371974-26025851","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"21.6","pituitary gland":"15.2","retina":"17.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"511.3","Inhibitory neurons":"711.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"6.1"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Skin - Outer root sheath cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039926","HPA040033"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA039926":"AB_10794205","HPA040033":"AB_2676809"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"}},{"Gene":"ATP8B1","Gene synonym":["ATPIC","BRIC","FIC1","PFIC","PFIC1"],"Ensembl":"ENSG00000081923","Gene description":"ATPase phospholipid transporting 8B1","Uniprot":["O43520"],"Chromosome":"18","Position":"57646426-57803315","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hearing","Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Intrahepatic cholestasis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"76.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"250.3","Enteroendocrine cells":"108.3","Gastric mucus-secreting cells":"117.5","Intestinal goblet cells":"163.7","Paneth cells":"113.1","Undifferentiated cells":"111.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018673","HPA018674"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm","Nuclear bodies"],"Antibody RRID":{"HPA018673":"AB_1845207","HPA018674":"AB_1845208"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.60e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"}},{"Gene":"ATP8B2","Gene synonym":["ATPID","KIAA1137"],"Ensembl":"ENSG00000143515","Gene description":"ATPase phospholipid transporting 8B2","Uniprot":["P98198"],"Chromosome":"1","Position":"154325525-154351304","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"25.9","Excitatory neurons":"28.1","Inhibitory neurons":"31.1","Prostatic glandular cells":"26.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.8","T-cells":"3.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"99.1"},"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046680","HPA061103"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA046680":"AB_2679749","HPA061103":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.60e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.29e-5"}},{"Gene":"ATP8B3","Gene synonym":["ATPIK"],"Ensembl":"ENSG00000130270","Gene description":"ATPase phospholipid transporting 8B3","Uniprot":["O60423"],"Chromosome":"19","Position":"1782075-1812276","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"5.9","testis":"21.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"9.9","Late spermatids":"11.1","Spermatocytes":"18.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"3.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.80e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"}},{"Gene":"ATP8B4","Gene synonym":["ATPIM","KIAA1939"],"Ensembl":"ENSG00000104043","Gene description":"ATPase phospholipid transporting 8B4 (putative)","Uniprot":["Q8TF62"],"Chromosome":"15","Position":"49858238-50182817","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"bone marrow":"78.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Microglial cells":"241.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"15.2","NK-cell":"11.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"15.2","NK-cells":"11.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"15.0"},"RNA tissue cell type enrichment":["Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040254"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA040254":"AB_10673028"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"}},{"Gene":"ATP9A","Gene synonym":["ATPIIA","KIAA0611"],"Ensembl":"ENSG00000054793","Gene description":"ATPase phospholipid transporting 9A (putative)","Uniprot":["O75110"],"Chromosome":"20","Position":"51596514-51768390","Protein class":["Enzymes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"67.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"110.6","Inhibitory neurons":"85.0","Oligodendrocytes":"85.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"4.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"4.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020699","HPA035630"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB020699":null,"HPA035630":"AB_10669526"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"}},{"Gene":"ATP9B","Gene synonym":["ATPIIB"],"Ensembl":"ENSG00000166377","Gene description":"ATPase phospholipid transporting 9B (putative)","Uniprot":["O43861"],"Chromosome":"18","Position":"79069285-79378287","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"88.3","Excitatory neurons":"124.3","Inhibitory neurons":"112.3","Oligodendrocyte precursor cells":"109.7","Oligodendrocytes":"148.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029364"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029364":"AB_10602595"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"}},{"Gene":"ATPSCKMT","Gene synonym":["FAM173B","JS-2"],"Ensembl":"ENSG00000150756","Gene description":"ATP synthase c subunit lysine N-methyltransferase","Uniprot":["Q6P4H8"],"Chromosome":"5","Position":"10225507-10249897","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074513"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA074513":"AB_2686698"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"}},{"Gene":"ATR","Gene synonym":["FRP1","MEC1","SCKL","SCKL1"],"Ensembl":"ENSG00000175054","Gene description":"ATR serine\/threonine kinase","Uniprot":["Q13535"],"Chromosome":"3","Position":"142449007-142578733","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054320"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA054320":"AB_2682448"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.39e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"}},{"Gene":"ATRAID","Gene synonym":["APR3","C2orf28","HSPC013","p18"],"Ensembl":"ENSG00000138085","Gene description":"All-trans retinoic acid induced differentiation factor","Uniprot":["Q6UW56"],"Chromosome":"2","Position":"27212027-27217178","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051353"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051353":"AB_2681451"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"}},{"Gene":"ATRN","Gene synonym":["DPPT-L","MGCA"],"Ensembl":"ENSG00000088812","Gene description":"Attractin","Uniprot":["O75882"],"Chromosome":"20","Position":"3471018-3651118","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Inflammatory response"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"100.2","Inhibitory neurons":"98.7","Oligodendrocyte precursor cells":"85.7","Oligodendrocytes":"80.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008853"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"27000000000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008853":"AB_1078248"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.19e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"}},{"Gene":"ATRNL1","Gene synonym":["ALP","FLJ45344","KIAA0534"],"Ensembl":"ENSG00000107518","Gene description":"Attractin like 1","Uniprot":["Q5VV63"],"Chromosome":"10","Position":"115093365-115948999","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"91.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Excitatory neurons":"2106.8","Inhibitory neurons":"1445.3","Oligodendrocyte precursor cells":"1395.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"91.1","white matter":"58.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Fibroblasts","Liver - Hepatic stellate cells","Prostate - Fibroblasts","Testis - Early spermatids","Testis - Spermatocytes","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038070"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA038070":"AB_10697237"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"}},{"Gene":"ATRX","Gene synonym":["JMS","MRX52","RAD54","XH2","XNP"],"Ensembl":"ENSG00000085224","Gene description":"ATRX chromatin remodeler","Uniprot":["P46100"],"Chromosome":"X","Position":"77504880-77786233","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["DNA damage","DNA repair","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001906","CAB009372","HPA064684","CAB068176"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB009372":"AB_2061023","CAB068176":"AB_2665665","HPA001906":"AB_1078249","HPA064684":"AB_2685321"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"}},{"Gene":"AUP1","Gene synonym":[],"Ensembl":"ENSG00000115307","Gene description":"AUP1 lipid droplet regulating VLDL assembly factor","Uniprot":["Q9Y679"],"Chromosome":"2","Position":"74526645-74529760","Protein class":["Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007674"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA007674":"AB_1078251"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.97e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"}},{"Gene":"AVL9","Gene synonym":["KIAA0241"],"Ensembl":"ENSG00000105778","Gene description":"AVL9 cell migration associated","Uniprot":["Q8NBF6"],"Chromosome":"7","Position":"32495426-32588726","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"92.5","Inhibitory neurons":"90.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050957"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA050957":"AB_2681289"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"AVPR1A","Gene synonym":["AVPR1"],"Ensembl":"ENSG00000166148","Gene description":"Arginine vasopressin receptor 1A","Uniprot":["P37288"],"Chromosome":"12","Position":"63142759-63151201","Protein class":["FDA approved drug targets","G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"56.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"22.9","Hepatocytes":"49.8","Sertoli cells":"27.6","Smooth muscle cells":"108.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"1.0","Myeloma":"2.7","Neuroblastoma":"1.1","prostate cancer":"1.2"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"7.0","hypothalamus":"3.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-6"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-4"}},{"Gene":"AVPR1B","Gene synonym":["AVPR3"],"Ensembl":"ENSG00000198049","Gene description":"Arginine vasopressin receptor 1B","Uniprot":["P47901"],"Chromosome":"1","Position":"206106936-206117699","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"pituitary gland":"6.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Enteroendocrine cells":"10.8","Glandular and luminal cells":"2.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"1.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Alpha cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075404"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA075404":"AB_2732291"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-3"}},{"Gene":"AVPR2","Gene synonym":["DIR","DIR3","V2R"],"Ensembl":"ENSG00000126895","Gene description":"Arginine vasopressin receptor 2","Uniprot":["P30518"],"Chromosome":"X","Position":"153902531-153907166","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Diabetes insipidus","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"8.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"32","RNA single cell type specific nTPM":{"Adipocytes":"46.6","Collecting duct cells":"41.4","Endothelial cells":"18.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"cerebellum":"3.9"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"28","RNA blood cell specific nTPM":{"intermediate monocyte":"3.6","non-classical monocyte":"3.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"29","RNA blood lineage specific nTPM":{"monocytes":"3.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Prostate - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"22","RNA pig brain regional specific nTPM":{"cerebellum":"6.8"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"}},{"Gene":"AWAT1","Gene synonym":["DGAT2L3"],"Ensembl":"ENSG00000204195","Gene description":"Acyl-CoA wax alcohol acyltransferase 1","Uniprot":["Q58HT5"],"Chromosome":"X","Position":"70234655-70240659","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"2.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063412"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063412":"AB_2685009"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"AWAT2","Gene synonym":["DGAT2L4","MFAT"],"Ensembl":"ENSG00000147160","Gene description":"Acyl-CoA wax alcohol acyltransferase 2","Uniprot":["Q6E213"],"Chromosome":"X","Position":"70040542-70049938","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"skin 1":"11.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"1.7","granulocytes":"1.8","Spermatocytes":"6.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"testis cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062748"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062748":"AB_2684862"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"AXIN1","Gene synonym":["PPP1R49"],"Ensembl":"ENSG00000103126","Gene description":"Axin 1","Uniprot":["O15169"],"Chromosome":"16","Position":"287440-352723","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"39.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012987"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoli","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB012987":"AB_2533178"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.38e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"}},{"Gene":"AXL","Gene synonym":["ARK","JTK11","Tyro7","UFO"],"Ensembl":"ENSG00000167601","Gene description":"AXL receptor tyrosine kinase","Uniprot":["P30530"],"Chromosome":"19","Position":"41219223-41261766","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Plasma proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Host cell receptor for virus entry","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["FDA approved drug targets","Oncogene","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"111.4","Langerhans cells":"190.8","Peritubular cells":"77.9","Sertoli cells":"138.2","Smooth muscle cells":"116.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"11.1","plasmacytoid DC":"25.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"25.7","NK-cells":"11.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032501","HPA037422","HPA037423","HPA075217"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":12100000,"Blood concentration - Conc. blood MS [pg\/L]":"72000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Actin filaments"],"Antibody RRID":{"CAB032501":"AB_2062572","HPA037422":"AB_10672347","HPA037423":"AB_2675470","HPA075217":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-3"}},{"Gene":"AZIN2","Gene synonym":["ADC","KIAA1945","ODC-p","ODC1L","ODCp"],"Ensembl":"ENSG00000142920","Gene description":"Antizyme inhibitor 2","Uniprot":["Q96A70"],"Chromosome":"1","Position":"33081104-33123492","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Polyamine biosynthesis","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"32.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"881.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"6.4","plasmacytoid DC":"18.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"18.9","granulocytes":"6.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Heart muscle - Fibroblasts","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028527"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028527":"AB_10602077"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"}},{"Gene":"B3GALNT1","Gene synonym":["B3GALT3","beta3Gal-T3","galT3","GLOB","P1"],"Ensembl":"ENSG00000169255","Gene description":"Beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)","Uniprot":["O75752"],"Chromosome":"3","Position":"161083883-161105411","Protein class":["Blood group antigen proteins","Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Blood group antigen","Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"53.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"79.7","Cardiomyocytes":"68.9","Horizontal cells":"40.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"8.8","NK-cell":"22.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"8.8","NK-cells":"22.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041204"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"400000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041204":"AB_10795585"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"}},{"Gene":"B3GALT2","Gene synonym":["beta3Gal-T2"],"Ensembl":"ENSG00000162630","Gene description":"Beta-1,3-galactosyltransferase 2","Uniprot":["O43825"],"Chromosome":"1","Position":"193178730-193186613","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.2","gallbladder":"15.0","heart muscle":"21.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"41.8","Cardiomyocytes":"44.0","Excitatory neurons":"27.1","Inhibitory neurons":"27.6","Leydig cells":"29.9","Peritubular cells":"19.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"MAIT T-cell":"8.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"53","RNA blood lineage specific nTPM":{"T-cells":"8.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Brain cancer":"2.3","lung cancer":"2.0","Neuroblastoma":"1.9","pancreatic cancer":"4.4","Sarcoma":"1.3","skin cancer":"1.9","thyroid cancer":"2.6"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078659"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA078659":"AB_2686887"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-3"}},{"Gene":"B3GALT5","Gene synonym":["B3GalT-V","B3T5","beta3Gal-T5","GLCT5"],"Ensembl":"ENSG00000183778","Gene description":"Beta-1,3-galactosyltransferase 5","Uniprot":["Q9Y2C3"],"Chromosome":"21","Position":"39556442-39673137","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"37.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"142.1","Enteroendocrine cells":"36.0","Intestinal goblet cells":"68.5","Paneth cells":"63.1","Proximal enterocytes":"84.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"5.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"11.5"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells (progenitors)","Colon - Colon enterocytes","Lung - Respiratory ciliated cells","Prostate - Urothelial cells","Skin - Eccrine sweat gland cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"8.6"},"Antibody":["HPA054092","HPA054684"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054092":"AB_2682375","HPA054684":"AB_2682573"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.36e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"}},{"Gene":"B3GAT1","Gene synonym":["CD57","GlcAT-P","HNK-1","LEU7","NK-1"],"Ensembl":"ENSG00000109956","Gene description":"Beta-1,3-glucuronyltransferase 1","Uniprot":["Q9P2W7"],"Chromosome":"11","Position":"134378504-134412242","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"195.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"26.6","Bipolar cells":"30.9","Excitatory neurons":"36.6","Horizontal cells":"41.7","Inhibitory neurons":"29.6","Muller glia cells":"97.3","Oligodendrocyte precursor cells":"31.8","Oligodendrocytes":"73.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"10.8","prostate cancer":"3.5","thyroid cancer":"4.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"T-cells":"1.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"7.7","skin cancer":"7.8"},"RNA tissue cell type enrichment":["Heart muscle - T-cells","Stomach - Chief cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002500","CAB010893","HPA069468","HPA074314"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB002500":"AB_563601","CAB010893":"AB_1078474","HPA069468":"AB_2686138","HPA074314":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"}},{"Gene":"B3GAT2","Gene synonym":["GlcAT-S"],"Ensembl":"ENSG00000112309","Gene description":"Beta-1,3-glucuronyltransferase 2","Uniprot":["Q9NPZ5"],"Chromosome":"6","Position":"70856679-70957060","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"29.8","retina":"18.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"100.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"20","RNA cancer specific FPKM":{"glioma":"4.7","testis cancer":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"2.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012059"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012059":"AB_2061050"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"}},{"Gene":"B3GAT3","Gene synonym":["GlcAT-I"],"Ensembl":"ENSG00000149541","Gene description":"Beta-1,3-glucuronyltransferase 3","Uniprot":["O94766"],"Chromosome":"11","Position":"62615296-62622154","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051328"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"990000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051328":"AB_2681444"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.69e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.11e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"}},{"Gene":"B3GNT10","Gene synonym":[],"Ensembl":"ENSG00000214654","Gene description":"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 10 (putative)","Uniprot":["A8MXE2"],"Chromosome":"9","Position":"120792403-120799918","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"8.6","Erythroid cells":"5.4","Late spermatids":"33.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"}},{"Gene":"B3GNT2","Gene synonym":["B3GN-T1","B3GN-T2","B3GNT-2","B3GNT1","BETA3GNT"],"Ensembl":"ENSG00000170340","Gene description":"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2","Uniprot":["Q9NY97"],"Chromosome":"2","Position":"62196115-62224731","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005997"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"99000000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA005997":"AB_1845234"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"B3GNT4","Gene synonym":["B3GN-T4","beta3Gn-T4"],"Ensembl":"ENSG00000176383","Gene description":"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4","Uniprot":["Q9C0J1"],"Chromosome":"12","Position":"122203681-122208952","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.9","skin 1":"3.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"3.1","Proximal tubular cells":"9.0","Sertoli cells":"13.8","Spermatogonia":"3.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Proximal tubular cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055261"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA055261":"AB_2682765"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.52e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"}},{"Gene":"B3GNT5","Gene synonym":["B3GN-T5","beta3Gn-T5"],"Ensembl":"ENSG00000176597","Gene description":"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5","Uniprot":["Q9BYG0"],"Chromosome":"3","Position":"183253253-183298504","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Developmental protein","Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"76.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"149.0","Langerhans cells":"171.5","Squamous epithelial cells":"170.0","Syncytiotrophoblasts":"162.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"5.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"5.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Urothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"cerebellum":"14.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017292"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA017292":"AB_1845237"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.09e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.23e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.30e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-3"}},{"Gene":"B4GALNT2","Gene synonym":["Cad","GALGT2","Sda"],"Ensembl":"ENSG00000167080","Gene description":"Beta-1,4-N-acetyl-galactosaminyltransferase 2","Uniprot":["Q8NHY0"],"Chromosome":"17","Position":"49132460-49176840","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"33.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"5.9","Distal enterocytes":"23.0","Enteroendocrine cells":"6.7","Glandular and luminal cells":"6.2","Intestinal goblet cells":"23.9","Proximal enterocytes":"15.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"6.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells (progenitors)","Colon - Colon enterocytes","Skin - Outer root sheath cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015721"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015721":"AB_1845245"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-4"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"}},{"Gene":"B4GALT1","Gene synonym":["beta4Gal-T1","GGTB2"],"Ensembl":"ENSG00000086062","Gene description":"Beta-1,4-galactosyltransferase 1","Uniprot":["P15291"],"Chromosome":"9","Position":"33104082-33167356","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"315.4","Langerhans cells":"360.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"215.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"305.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010806","HPA010807"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"97000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA010806":"AB_1078255","HPA010807":"AB_1078254"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.85e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"}},{"Gene":"B4GALT2","Gene synonym":["beta4Gal-T2"],"Ensembl":"ENSG00000117411","Gene description":"Beta-1,4-galactosyltransferase 2","Uniprot":["O60909"],"Chromosome":"1","Position":"43978943-43991170","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"50.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007620","HPA047739"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3100000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA007620":"AB_2667879","HPA047739":"AB_2680141"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.96e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.62e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"}},{"Gene":"B4GALT7","Gene synonym":["beta4Gal-T7","XGALT-1"],"Ensembl":"ENSG00000027847","Gene description":"Beta-1,4-galactosyltransferase 7","Uniprot":["Q9UBV7"],"Chromosome":"5","Position":"177600132-177610330","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Dwarfism","Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"155.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042330"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042330":"AB_10796576"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"}},{"Gene":"B9D1","Gene synonym":["B9","EPPB9","MKS9","MKSR-1"],"Ensembl":"ENSG00000108641","Gene description":"B9 domain containing 1","Uniprot":["Q9UPM9"],"Chromosome":"17","Position":"19334308-19378193","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Joubert syndrome","Meckel syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"248.9","Endometrial ciliated cells":"105.2","Late spermatids":"181.7","Respiratory ciliated cells":"125.7","Spermatocytes":"126.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022957"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA022957":"AB_1848220"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"}},{"Gene":"BACE1","Gene synonym":["BACE"],"Ensembl":"ENSG00000186318","Gene description":"Beta-secretase 1","Uniprot":["P56817"],"Chromosome":"11","Position":"117285207-117316259","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"119.1","pancreas":"271.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"155.1","Late spermatids":"358.4","Oligodendrocytes":"94.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Pancreas - Exocrine glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016358"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB016358":"AB_626716"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.76e-4"}},{"Gene":"BACE2","Gene synonym":["AEPLC","ALP56","CEAP1","DRAP"],"Ensembl":"ENSG00000182240","Gene description":"Beta-secretase 2","Uniprot":["Q9Y5Z0"],"Chromosome":"21","Position":"41167801-41282530","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Aspartyl protease","Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"26.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Melanocytes":"264.7","Mucus glandular cells":"252.0","Syncytiotrophoblasts":"528.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"2.9","eosinophil":"5.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"5.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"46.1"},"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Lung - Fibroblast_2","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035416"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035416":"AB_2732467"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.86e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"}},{"Gene":"BAIAP2","Gene synonym":["BAP2","IRSp53","WAML"],"Ensembl":"ENSG00000175866","Gene description":"BAR\/IMD domain containing adaptor protein 2","Uniprot":["Q9UQB8"],"Chromosome":"17","Position":"81035122-81117432","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"19.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skin - Keratinocyte (other)","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023310","HPA027421"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023310":"AB_1845264","HPA027421":"AB_10602392"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.58e-6"}},{"Gene":"BAK1","Gene synonym":["BAK","BCL2L7","CDN1"],"Ensembl":"ENSG00000030110","Gene description":"BCL2 antagonist\/killer 1","Uniprot":["Q16611"],"Chromosome":"6","Position":"33572547-33580293","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"64.6","Proximal enterocytes":"84.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005029"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB005029":"AB_562051"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.71e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.52e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.64e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.64e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"}},{"Gene":"BAMBI","Gene synonym":["NMA"],"Ensembl":"ENSG00000095739","Gene description":"BMP and activin membrane bound inhibitor","Uniprot":["Q13145"],"Chromosome":"10","Position":"28677510-28682932","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"81.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"167.3","Breast myoepithelial cells":"167.9","Granulosa cells":"319.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"357.8"},"RNA tissue cell type enrichment":["Lung - Fibroblast_1","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010819","HPA010866"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Vesicles","Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoli fibrillar center","Lipid droplets"],"Antibody RRID":{"HPA010819":"AB_2668371","HPA010866":"AB_10601686"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.42e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"}},{"Gene":"BAP1","Gene synonym":["hucep-6","KIAA0272","UCHL2"],"Ensembl":"ENSG00000163930","Gene description":"BRCA1 associated protein 1","Uniprot":["Q92560"],"Chromosome":"3","Position":"52401008-52410008","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"75.9","Late spermatids":"63.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004322","HPA028814","HPA028815","HPA055560"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004322":"AB_626723","HPA028814":"AB_10602393","HPA028815":"AB_2672785","HPA055560":"AB_2682850"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.29e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"}},{"Gene":"BBS1","Gene synonym":["FLJ23590"],"Ensembl":"ENSG00000174483","Gene description":"Bardet-Biedl syndrome 1","Uniprot":["Q8NFJ9"],"Chromosome":"11","Position":"66510606-66533613","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Olfaction","Protein transport","Sensory transduction","Transport","Vision"],"Molecular function":null,"Disease involvement":["Bardet-Biedl syndrome","Ciliopathy","Disease variant","Intellectual disability","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"19.3","Excitatory neurons":"28.0","Inhibitory neurons":"27.8","Microglial cells":"13.7","Oligodendrocyte precursor cells":"13.0","Rod photoreceptor cells":"11.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058283"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Midbody"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Midbody"],"Subcellular additional location":null,"Antibody RRID":{"HPA058283":"AB_2683667"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-4"}},{"Gene":"BBS4","Gene synonym":[],"Ensembl":"ENSG00000140463","Gene description":"Bardet-Biedl syndrome 4","Uniprot":["Q96RK4"],"Chromosome":"15","Position":"72686179-72738475","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Protein transport","Sensory transduction","Transport","Vision"],"Molecular function":null,"Disease involvement":["Bardet-Biedl syndrome","Ciliopathy","Disease variant","Intellectual disability","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"106.8","Rod photoreceptor cells":"93.5","Spermatocytes":"87.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039418"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039418":"AB_10672962"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.57e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"}},{"Gene":"BBS9","Gene synonym":["B1","PTHB1"],"Ensembl":"ENSG00000122507","Gene description":"Bardet-Biedl syndrome 9","Uniprot":["Q3SYG4"],"Chromosome":"7","Position":"33109557-33877180","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Protein transport","Sensory transduction","Transport","Vision"],"Molecular function":null,"Disease involvement":["Bardet-Biedl syndrome","Ciliopathy","Disease variant","Intellectual disability","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"121.8","Excitatory neurons":"160.1","Inhibitory neurons":"155.4","Microglial cells":"259.1","Oligodendrocyte precursor cells":"228.6","Oligodendrocytes":"346.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021289"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021289":"AB_1845286"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.86e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-3"}},{"Gene":"BBX","Gene synonym":["HBP2","HSPC339","MDS001"],"Ensembl":"ENSG00000114439","Gene description":"BBX high mobility group box domain containing","Uniprot":["Q8WY36"],"Chromosome":"3","Position":"107522936-107811339","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1122.6","Late spermatids":"656.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006049","HPA050646"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA006049":"AB_2667504","HPA050646":"AB_2681200"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"}},{"Gene":"BCAM","Gene synonym":["CD239","LU"],"Ensembl":"ENSG00000187244","Gene description":"Basal cell adhesion molecule (Lutheran blood group)","Uniprot":["P50895"],"Chromosome":"19","Position":"44809071-44821421","Protein class":["Blood group antigen proteins","CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Blood group antigen","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"316.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"363.1","Basal respiratory cells":"438.9","Collecting duct cells":"494.2","Cytotrophoblasts":"694.8","Syncytiotrophoblasts":"411.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"493.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005654"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA005654":"AB_2667378"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.31e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.94e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-3"}},{"Gene":"BCAP29","Gene synonym":["BAP29","DKFZp686M2086"],"Ensembl":"ENSG00000075790","Gene description":"B cell receptor associated protein 29","Uniprot":["Q9UHQ4"],"Chromosome":"7","Position":"107580246-107629170","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"80.0","Inhibitory neurons":"69.7","Oligodendrocyte precursor cells":"48.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029215","HPA049694"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029215":"AB_10602331","HPA049694":"AB_2680854"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"}},{"Gene":"BCAP31","Gene synonym":["6C6-Ag","BAP31","CDM","DXS1357E"],"Ensembl":"ENSG00000185825","Gene description":"B cell receptor associated protein 31","Uniprot":["P51572"],"Chromosome":"X","Position":"153700492-153724565","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","ER-Golgi transport","Host-virus interaction","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Dystonia","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"567.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003906","CAB015350","CAB015424"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB015350":"AB_2243544","CAB015424":"AB_781567","HPA003906":"AB_1078270"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.87e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"BCKDHA","Gene synonym":["MSU","OVD1A"],"Ensembl":"ENSG00000248098","Gene description":"Branched chain keto acid dehydrogenase E1 subunit alpha","Uniprot":["P12694"],"Chromosome":"19","Position":"41397808-41425002","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Maple syrup urine disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"26.4","Erythroid cells":"14.4","Gastric mucus-secreting cells":"25.0","Plasma cells":"19.7","Squamous epithelial cells":"26.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036640"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7700","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036640":"AB_10671964"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.37e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.33e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.27e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"}},{"Gene":"BCL2","Gene synonym":["Bcl-2","PPP1R50"],"Ensembl":"ENSG00000171791","Gene description":"BCL2 apoptosis regulator","Uniprot":["P10415"],"Chromosome":"18","Position":"63123346-63320128","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"263.2","Schwann cells":"121.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"B-cells":"5.4","T-cells":"8.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"41.9","Myeloma":"64.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Colon - Enteric glia cells","Skeletal muscle - Skeletal myocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000003","CAB080071","CAB080083"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB000003":"AB_2064429","CAB080071":null,"CAB080083":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.13e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.47e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"}},{"Gene":"BCL2L1","Gene synonym":["Bcl-X","bcl-xL","bcl-xS","BCL2L","BCLX","PPP1R52"],"Ensembl":"ENSG00000171552","Gene description":"BCL2 like 1","Uniprot":["Q07817"],"Chromosome":"20","Position":"31664452-31723989","Protein class":["Cancer-related genes","Predicted membrane proteins","RAS pathway related proteins","Transporters"],"Biological process":["Apoptosis","Endocytosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"221.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035734","CAB072801"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB072801":null,"HPA035734":"AB_2674757"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.10e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.57e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.87e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.89e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"}},{"Gene":"BCL2L10","Gene synonym":["BCL-B","Boo","Diva"],"Ensembl":"ENSG00000137875","Gene description":"BCL2 like 10","Uniprot":["Q9HD36"],"Chromosome":"15","Position":"52109263-52112775","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"9.6","skin 1":"6.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"7.7","Basal squamous epithelial cells":"6.5","Proximal enterocytes":"12.3","Proximal tubular cells":"8.5","Squamous epithelial cells":"8.1","Suprabasal keratinocytes":"10.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"6.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042222"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042222":"AB_10794271"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"}},{"Gene":"BCL2L13","Gene synonym":["BCL-RAMBO","MIL1"],"Ensembl":"ENSG00000099968","Gene description":"BCL2 like 13","Uniprot":["Q9BXK5"],"Chromosome":"22","Position":"17628855-17730855","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"59.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"154.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002052","HPA030994","HPA050377"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB002052":"AB_563431","HPA030994":"AB_10795024","HPA050377":"AB_2681107"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.96e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"}},{"Gene":"BCL2L2","Gene synonym":["BCL-W","KIAA0271","PPP1R51"],"Ensembl":"ENSG00000129473","Gene description":"BCL2 like 2","Uniprot":["Q92843"],"Chromosome":"14","Position":"23298790-23311751","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB040539","HPA048740"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB040539":null,"HPA048740":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.99e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"}},{"Gene":"BCS1L","Gene synonym":["BCS","BJS","h-BCS","Hs.6719"],"Ensembl":"ENSG00000074582","Gene description":"BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone","Uniprot":["Q9Y276"],"Chromosome":"2","Position":"218658764-218663443","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Deafness","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037700","HPA037701"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037700":"AB_10794619","HPA037701":"AB_10805235"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.31e-4"}},{"Gene":"BDH1","Gene synonym":["BDH","SDR9C1"],"Ensembl":"ENSG00000161267","Gene description":"3-hydroxybutyrate dehydrogenase 1","Uniprot":["Q02338"],"Chromosome":"3","Position":"197509783-197573323","Protein class":["Candidate cardiovascular disease genes","Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Allosteric enzyme","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"324.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"92.7","Hepatocytes":"116.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Prostate - Prostate glandular cells","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030947","HPA058709"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA030947":"AB_10669548","HPA058709":"AB_2683797"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.86e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.12e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"BDKRB1","Gene synonym":["B1BKR","BKR1","bradyb1"],"Ensembl":"ENSG00000100739","Gene description":"Bradykinin receptor B1","Uniprot":["P46663"],"Chromosome":"14","Position":"96256210-96268967","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"urinary bladder":"23.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"36.4","Basal squamous epithelial cells":"30.2","Squamous epithelial cells":"20.6","Suprabasal keratinocytes":"23.5","Thymic epithelial cells":"25.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"18.6"},"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Skin - Keratinocyte (other)","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002935"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002935":"AB_1078274"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"}},{"Gene":"BDKRB2","Gene synonym":["BK-2"],"Ensembl":"ENSG00000168398","Gene description":"Bradykinin receptor B2","Uniprot":["P30411"],"Chromosome":"14","Position":"96204679-96244166","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"urinary bladder":"41.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"16.3","Ionocytes":"16.5","Langerhans cells":"19.2","Squamous epithelial cells":"15.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003551","HPA050841"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"HPA003551":null,"HPA050841":"AB_2681254"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"}},{"Gene":"BDNF","Gene synonym":[],"Ensembl":"ENSG00000176697","Gene description":"Brain derived neurotrophic factor","Uniprot":["P23560"],"Chromosome":"11","Position":"27654893-27722058","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"20.7","Bipolar cells":"9.8","Cardiomyocytes":"11.6","Excitatory neurons":"22.0","Skeletal myocytes":"7.9","Smooth muscle cells":"13.1","Theca cells":"8.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009564"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":16000000,"Blood concentration - Conc. blood MS [pg\/L]":"24000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009564":"AB_2064213"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-3"}},{"Gene":"BEAN1","Gene synonym":["SCA31"],"Ensembl":"ENSG00000166546","Gene description":"Brain expressed associated with NEDD4 1","Uniprot":["Q3B7T3"],"Chromosome":"16","Position":"66427295-66493529","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"5.9","Early spermatids":"9.9","Excitatory neurons":"9.7","Extravillous trophoblasts":"12.7","Inhibitory neurons":"7.6","Late spermatids":"14.2","Melanocytes":"7.0","Oligodendrocyte precursor cells":"7.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"5.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053851"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA053851":"AB_2682280"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"}},{"Gene":"BEST1","Gene synonym":["BEST","BMD","RP50","VMD2"],"Ensembl":"ENSG00000167995","Gene description":"Bestrophin 1","Uniprot":["O76090"],"Chromosome":"11","Position":"61950063-61965515","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"26.3","brain":"41.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"40.8","Oligodendrocytes":"40.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"2.0","melanoma":"6.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"37.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"37.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"20.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057464"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057464":"AB_2683444"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"}},{"Gene":"BEST2","Gene synonym":["FLJ20132","VMD2L1"],"Ensembl":"ENSG00000039987","Gene description":"Bestrophin 2","Uniprot":["Q8NFU1"],"Chromosome":"19","Position":"12751702-12758458","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"45.3","skin 1":"17.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"19","RNA single cell type specific nTPM":{"Intestinal goblet cells":"108.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"1.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"1.7"},"Antibody":["HPA046229"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046229":"AB_10966140"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-5"}},{"Gene":"BEST3","Gene synonym":["MGC13168","MGC40411","VMD2L3"],"Ensembl":"ENSG00000127325","Gene description":"Bestrophin 3","Uniprot":["Q8N1M1"],"Chromosome":"12","Position":"69643360-69699476","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"skeletal muscle":"69.1","tongue":"55.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"67.4","Skeletal myocytes":"139.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"2.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"9.4","lung cancer":"7.9","lymphoma":"22.6","Myeloma":"7.2","Sarcoma":"6.8"},"RNA tissue cell type enrichment":["Pancreas - Beta cells","Skin - Inner root sheath cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054582"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054582":"AB_2682530"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-7"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"}},{"Gene":"BEST4","Gene synonym":["VMD2L2"],"Ensembl":"ENSG00000142959","Gene description":"Bestrophin 4","Uniprot":["Q8NFU0"],"Chromosome":"1","Position":"44783585-44788170","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"choroid plexus":"16.4","fallopian tube":"8.3","intestine":"27.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Paneth cells":"1427.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Respiratory ciliated cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058564"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058564":"AB_2683759"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"}},{"Gene":"BET1","Gene synonym":["hbet1"],"Ensembl":"ENSG00000105829","Gene description":"Bet1 golgi vesicular membrane trafficking protein","Uniprot":["O15155"],"Chromosome":"7","Position":"93962762-94004382","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"195.6","Syncytiotrophoblasts":"147.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-3"}},{"Gene":"BET1L","Gene synonym":["GOLIM3","GS15"],"Ensembl":"ENSG00000177951","Gene description":"Bet1 golgi vesicular membrane trafficking protein like","Uniprot":["Q9NYM9"],"Chromosome":"11","Position":"167784-207428","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"138.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039819"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA039819":"AB_10673020"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.80e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"}},{"Gene":"BFAR","Gene synonym":["BAR","RNF47"],"Ensembl":"ENSG00000103429","Gene description":"Bifunctional apoptosis regulator","Uniprot":["Q9NZS9"],"Chromosome":"16","Position":"14632931-14669236","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.74e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"}},{"Gene":"BIK","Gene synonym":["NBK"],"Ensembl":"ENSG00000100290","Gene description":"BCL2 interacting killer","Uniprot":["Q13323"],"Chromosome":"22","Position":"43110750-43129712","Protein class":["Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"17.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"329.7","Club cells":"135.0","Ionocytes":"376.2","Paneth cells":"126.5","Respiratory ciliated cells":"157.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"72.9","plasmacytoid DC":"58.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"55.6"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Colon enterocytes","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051360"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051360":"AB_2681453"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"}},{"Gene":"BIRC3","Gene synonym":["API2","c-IAP2","cIAP2","hiap-1","MALT2","MIHC","RNF49"],"Ensembl":"ENSG00000023445","Gene description":"Baculoviral IAP repeat containing 3","Uniprot":["Q13489"],"Chromosome":"11","Position":"102317450-102339403","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"89.0","lymphoid tissue":"141.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"737.3","Langerhans cells":"1603.7","monocytes":"693.9","Proximal enterocytes":"883.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"209.0","naive B-cell":"159.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"B-cells":"209.0","T-cells":"83.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"122.5"},"RNA tissue cell type enrichment":["Pancreas - Ductal cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002317"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002317":"AB_1846748"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.60e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.35e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.28e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.66e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"}},{"Gene":"BIRC5","Gene synonym":["API4","EPR-1","survivin"],"Ensembl":"ENSG00000089685","Gene description":"Baculoviral IAP repeat containing 5","Uniprot":["O15392"],"Chromosome":"17","Position":"78214186-78225636","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle","Cell division","Chromosome partition","Mitosis","Transcription","Transcription regulation"],"Molecular function":["Protease inhibitor","Repressor","Thiol protease inhibitor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"37.9","lymphoid tissue":"41.0","testis":"19.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"82.2","Early spermatids":"97.9","Erythroid cells":"144.2","Extravillous trophoblasts":"167.9","Late spermatids":"73.8","Plasma cells":"74.5","Spermatocytes":"175.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"14.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"14.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Mitotic cells (Colon)","Heart muscle - Mitotic cells (Heart)","Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Testis - Early spermatids","Thyroid - Mitotic cells (Thyroid)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002830","CAB004270"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Cytokinetic bridge"],"Subcellular additional location":null,"Antibody RRID":{"CAB004270":"AB_628302","HPA002830":"AB_1857672"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.28e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.49e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"}},{"Gene":"BIRC6","Gene synonym":["BRUCE"],"Ensembl":"ENSG00000115760","Gene description":"Baculoviral IAP repeat containing 6","Uniprot":["Q9NR09"],"Chromosome":"2","Position":"32357028-32618899","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle","Cell division","Mitosis","Ubl conjugation pathway"],"Molecular function":["Protease inhibitor","Thiol protease inhibitor","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"268.0","Inhibitory neurons":"284.6","Oligodendrocytes":"341.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"9.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"9.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074409","HPA074738"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Mitotic spindle"],"Antibody RRID":{"HPA074409":null,"HPA074738":"AB_2686710"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"}},{"Gene":"BLCAP","Gene synonym":["BC10"],"Ensembl":"ENSG00000166619","Gene description":"BLCAP apoptosis inducing factor","Uniprot":["P62952"],"Chromosome":"20","Position":"37492472-37527931","Protein class":["Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"466.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Prostate - Prostate basal glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047390"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA047390":"AB_2680025"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.40e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.28e-5"}},{"Gene":"BMPR1A","Gene synonym":["ACVRLK3","ALK3","CD292"],"Ensembl":"ENSG00000107779","Gene description":"Bone morphogenetic protein receptor type 1A","Uniprot":["P36894"],"Chromosome":"10","Position":"86756601-86932825","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"138.2","Inhibitory neurons":"78.2","Oligodendrocyte precursor cells":"117.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019398"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB019398":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.93e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"BMPR1B","Gene synonym":["ALK6","CDw293"],"Ensembl":"ENSG00000138696","Gene description":"Bone morphogenetic protein receptor type 1B","Uniprot":["O00238"],"Chromosome":"4","Position":"94757955-95158448","Protein class":["CD markers","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Chondrogenesis"],"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"20.1","cervix":"24.7","prostate":"22.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"465.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"32.4","prostate cancer":"24.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"12.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Liver - Hepatic stellate cells","Lung - Respiratory ciliated cells","Prostate - Prostate glandular cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.84e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"}},{"Gene":"BMPR2","Gene synonym":["BMPR-II","BMPR3","BRK-3","PPH1","T-ALK"],"Ensembl":"ENSG00000204217","Gene description":"Bone morphogenetic protein receptor type 2","Uniprot":["Q13873"],"Chromosome":"2","Position":"202376327-202567751","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"199.2","Inhibitory neurons":"185.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Lung - Endothelial cells","Skeletal muscle - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017385","HPA049014"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA017385":"AB_1845397","HPA049014":"AB_2680599"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"}},{"Gene":"BMT2","Gene synonym":["C7orf60","DKFZp762M126","FLJ31818","SAMTOR"],"Ensembl":"ENSG00000164603","Gene description":"Base methyltransferase of 25S rRNA 2 homolog","Uniprot":["Q1RMZ1"],"Chromosome":"7","Position":"112819147-112939875","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"72.0","Inhibitory neurons":"59.2","Microglial cells":"47.4","Oligodendrocyte precursor cells":"67.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044405","HPA050733"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA044405":"AB_10959783","HPA050733":"AB_2681223"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"}},{"Gene":"BNIP1","Gene synonym":["Nip1","SEC20"],"Ensembl":"ENSG00000113734","Gene description":"BCL2 interacting protein 1","Uniprot":["Q12981"],"Chromosome":"5","Position":"173144442-173164387","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","ER-Golgi transport","Host-virus interaction","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008009","HPA008149"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA008009":"AB_1078291","HPA008149":"AB_2667993"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"}},{"Gene":"BNIP3","Gene synonym":["Nip3"],"Ensembl":"ENSG00000176171","Gene description":"BCL2 interacting protein 3","Uniprot":["Q12983"],"Chromosome":"10","Position":"131966455-131982013","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"361.5","skeletal muscle":"214.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"548.2","Hepatocytes":"465.3","Proximal tubular cells":"586.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003015","CAB011676"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011676":null,"HPA003015":"AB_1078290"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.55e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"}},{"Gene":"BNIP3L","Gene synonym":["BNIP3a","Nix"],"Ensembl":"ENSG00000104765","Gene description":"BCL2 interacting protein 3 like","Uniprot":["O60238"],"Chromosome":"8","Position":"26383054-26505636","Protein class":["Cancer-related genes","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015652","CAB025371"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"CAB025371":null,"HPA015652":"AB_1845406"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.92e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.95e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-3"}},{"Gene":"BOC","Gene synonym":["CDON2"],"Ensembl":"ENSG00000144857","Gene description":"BOC cell adhesion associated, oncogene regulated","Uniprot":["Q9BWV1"],"Chromosome":"3","Position":"113211003-113287459","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"69.6","Basal keratinocytes":"35.5","Basal squamous epithelial cells":"59.4","Fibroblasts":"57.8","Leydig cells":"84.3","Peritubular cells":"45.0","Thymic epithelial cells":"36.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Lung - Fibroblast_2","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025806"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7900000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nuclear bodies","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB025806":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.89e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.18e-5"}},{"Gene":"BPNT2","Gene synonym":["FLJ20421","gPAPP","IMPA3","IMPAD1"],"Ensembl":"ENSG00000104331","Gene description":"3'(2'), 5'-bisphosphate nucleotidase 2","Uniprot":["Q9NX62"],"Chromosome":"8","Position":"56957931-56993867","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009411"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"480000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA009411":"AB_1079138"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"BRI3","Gene synonym":[],"Ensembl":"ENSG00000164713","Gene description":"Brain protein I3","Uniprot":["O95415"],"Chromosome":"7","Position":"98252379-98310441","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"846.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"42.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042215"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042215":"AB_10794790"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.35e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"}},{"Gene":"BRI3BP","Gene synonym":["BNAS1","HCCR-2","HCCRBP-3","KG19"],"Ensembl":"ENSG00000184992","Gene description":"BRI3 binding protein","Uniprot":["Q8WY22"],"Chromosome":"12","Position":"124993645-125031231","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"20.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"167.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"13.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Ductal cells","Skin - Sebaceous gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014957"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA014957":"AB_1845447"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.87e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"}},{"Gene":"BRICD5","Gene synonym":["C16orf79","MGC21830"],"Ensembl":"ENSG00000182685","Gene description":"BRICHOS domain containing 5","Uniprot":["Q6PL45"],"Chromosome":"16","Position":"2209253-2211950","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Sertoli cells":"55.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"3.1"},"Antibody":["HPA063522"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA063522":"AB_2685029"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.74e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.01e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.06e-5"}},{"Gene":"BRINP1","Gene synonym":["DBC1","DBCCR1","FAM5A"],"Ensembl":"ENSG00000078725","Gene description":"BMP\/retinoic acid inducible neural specific 1","Uniprot":["O60477"],"Chromosome":"9","Position":"119153458-119369435","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":["Cell cycle","Growth arrest"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"43.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"173.3","Excitatory neurons":"281.6","Inhibitory neurons":"159.2","Oligodendrocyte precursor cells":"195.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"6.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Colon enteroendocrine cells","Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038828"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Microtubules"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA038828":"AB_10670909"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"}},{"Gene":"BRINP3","Gene synonym":["DBCCR1L","DBCCR1L1","FAM5C"],"Ensembl":"ENSG00000162670","Gene description":"BMP\/retinoic acid inducible neural specific 3","Uniprot":["Q76B58"],"Chromosome":"1","Position":"190097658-190478404","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell cycle","Growth arrest"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"27.1","intestine":"17.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"258.4","Excitatory neurons":"328.9","Oligodendrocyte precursor cells":"1033.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"breast cancer":"3.4","glioma":"8.6","prostate cancer":"3.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"20.2"},"RNA tissue cell type enrichment":["Lung - Fibroblast_2","Prostate - Prostate glandular cells","Testis - Early spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054693"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054693":"AB_2682575"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"}},{"Gene":"BRMS1","Gene synonym":["DKFZP564A063"],"Ensembl":"ENSG00000174744","Gene description":"BRMS1 transcriptional repressor and anoikis regulator","Uniprot":["Q9HCU9"],"Chromosome":"11","Position":"66337333-66345125","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Transcription","Transcription regulation"],"Molecular function":["Repressor"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010824","HPA019637"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"CAB010824":null,"HPA019637":"AB_1845448"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.74e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"}},{"Gene":"BRS3","Gene synonym":["BB3","BB3R","BBR3"],"Ensembl":"ENSG00000102239","Gene description":"Bombesin receptor subtype 3","Uniprot":["P32247"],"Chromosome":"X","Position":"136487947-136493780","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"26","RNA tissue specific nTPM":{"epididymis":"25.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"2.1","Pancreatic endocrine cells":"5.2","Spermatogonia":"1.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Alpha cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hypothalamus":"6.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 26: NCI-H716 - Unknown function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"}},{"Gene":"BRSK1","Gene synonym":["KIAA1811"],"Ensembl":"ENSG00000160469","Gene description":"BR serine\/threonine kinase 1","Uniprot":["Q8TDC3"],"Chromosome":"19","Position":"55282072-55312562","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","DNA damage","Neurogenesis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"141.8","pituitary gland":"53.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"29.9","Excitatory neurons":"29.7","Horizontal cells":"35.9","Inhibitory neurons":"26.9","Oligodendrocyte precursor cells":"16.4","Oligodendrocytes":"27.7","Proximal enterocytes":"21.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"12.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"44.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Lung - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021212","HPA061719"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA021212":"AB_1845455","HPA061719":"AB_2684593"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.98e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"}},{"Gene":"BRSK2","Gene synonym":["C11orf7","PEN11B","STK29"],"Ensembl":"ENSG00000174672","Gene description":"BR serine\/threonine kinase 2","Uniprot":["Q8IWQ3"],"Chromosome":"11","Position":"1389899-1462689","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cell cycle","Cell division","Exocytosis","Mitosis","Neurogenesis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"37.8","pancreas":"104.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"22.1","Bipolar cells":"81.9","Excitatory neurons":"35.0","Horizontal cells":"55.8","Inhibitory neurons":"23.0","Muller glia cells":"21.2","Oligodendrocytes":"19.5","Rod photoreceptor cells":"31.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"18.6"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073690"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA073690":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"}},{"Gene":"BSCL2","Gene synonym":["GNG3LG","seipin","SPG17"],"Ensembl":"ENSG00000168000","Gene description":"BSCL2 lipid droplet biogenesis associated, seipin","Uniprot":["Q96G97"],"Chromosome":"11","Position":"62690275-62709845","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":null,"Disease involvement":["Congenital generalized lipodystrophy","Diabetes mellitus","Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"292.1","pituitary gland":"237.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"28.9","Gastric mucus-secreting cells":"20.3","Late spermatids":"39.6","Plasma cells":"65.6","Spermatocytes":"24.3","Squamous epithelial cells":"25.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042394"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042394":"AB_10794047"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"}},{"Gene":"BSDC1","Gene synonym":["FLJ10276","RP4-811H24.7"],"Ensembl":"ENSG00000160058","Gene description":"BSD domain containing 1","Uniprot":["Q9NW68"],"Chromosome":"1","Position":"32364633-32394731","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"37.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"37.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031358","HPA031360"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA031358":"AB_2673841","HPA031360":"AB_10601120"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.82e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"}},{"Gene":"BSG","Gene synonym":["CD147","EMMPRIN","EMPRIN","OK"],"Ensembl":"ENSG00000172270","Gene description":"Basigin (Ok blood group)","Uniprot":["P35613"],"Chromosome":"19","Position":"571277-583494","Protein class":["Blood group antigen proteins","CD markers","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis","Host-virus interaction"],"Molecular function":["Blood group antigen","Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"1535.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"1426.9","Distal enterocytes":"1458.4","Syncytiotrophoblasts":"1590.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Heart muscle - Cardiomyocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002427","HPA036048","HPA074870"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"340000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB002427":"AB_563501","HPA036048":"AB_2674917","HPA074870":"AB_2686719"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.59e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.48e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.95e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"}},{"Gene":"BSND","Gene synonym":["BART","DFNB73"],"Ensembl":"ENSG00000162399","Gene description":"Barttin CLCNK type accessory subunit beta","Uniprot":["Q8WZ55"],"Chromosome":"1","Position":"54998933-55017172","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Bartter syndrome","Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"kidney":"9.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Collecting duct cells":"9.8","Distal tubular cells":"9.3","Ionocytes":"17.2","Salivary duct cells":"6.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"renal cancer":"3.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053836","HPA060617"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053836":"AB_2682277","HPA060617":"AB_2732651"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"BST2","Gene synonym":["CD317","tetherin"],"Ensembl":"ENSG00000130303","Gene description":"Bone marrow stromal cell antigen 2","Uniprot":["Q10589"],"Chromosome":"19","Position":"17402939-17405630","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiviral defense","B-cell activation","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"694.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"1207.4","Hofbauer cells":"438.6","Peritubular cells":"420.0","Theca cells":"497.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017060","HPA073472"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA017060":"AB_1845467","HPA073472":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.69e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.56e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.22e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"}},{"Gene":"BTBD9","Gene synonym":["dJ322I12.1","KIAA1880"],"Ensembl":"ENSG00000183826","Gene description":"BTB domain containing 9","Uniprot":["Q96Q07"],"Chromosome":"6","Position":"38168451-38640148","Protein class":["Disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Astrocytes":"185.4","Excitatory neurons":"384.8","Inhibitory neurons":"251.3","Microglial cells":"138.6","Oligodendrocyte precursor cells":"185.3","Oligodendrocytes":"206.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041930"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA041930":"AB_10795270"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.20e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"}},{"Gene":"BTC","Gene synonym":[],"Ensembl":"ENSG00000174808","Gene description":"Betacellulin","Uniprot":["P35070"],"Chromosome":"4","Position":"74744759-74794523","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor","Mitogen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"25.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"18.8","Respiratory ciliated cells":"25.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"16.3"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":314000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.10e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"}},{"Gene":"BTG3","Gene synonym":["ANA","ANA\/BTG3","APRO4","tob55"],"Ensembl":"ENSG00000154640","Gene description":"BTG anti-proliferation factor 3","Uniprot":["Q14201"],"Chromosome":"21","Position":"17593653-17612945","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"429.6","Syncytiotrophoblasts":"1707.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"31.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018400"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018400":"AB_1845487"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.16e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.37e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"}},{"Gene":"BTLA","Gene synonym":["BTLA1","CD272"],"Ensembl":"ENSG00000186265","Gene description":"B and T lymphocyte associated","Uniprot":["Q7Z6A9"],"Chromosome":"3","Position":"112463966-112499472","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"lymphoid tissue":"28.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"64.2","dendritic cells":"18.5","Plasma cells":"21.9","Schwann cells":"20.8","T-cells":"9.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory B-cell":"65.0","naive B-cell":"96.5","plasmacytoid DC":"24.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"96.5","dendritic cells":"24.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"3.4","Myeloma":"12.4"},"RNA tissue cell type enrichment":["Breast - Plasma cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047211","HPA062029"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047211":"AB_2679983","HPA062029":"AB_2684665"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"}},{"Gene":"BTN1A1","Gene synonym":["BT","BTN","BTN1"],"Ensembl":"ENSG00000124557","Gene description":"Butyrophilin subfamily 1 member A1","Uniprot":["Q13410"],"Chromosome":"6","Position":"26501221-26510422","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"39","RNA tissue specific nTPM":{"breast":"32.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"52","RNA single cell type specific nTPM":{"Breast glandular cells":"109.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"2.1","naive B-cell":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011126","CAB037340"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 5: Breast - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037340":null,"HPA011126":"AB_1845491"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-4"}},{"Gene":"BTN2A1","Gene synonym":["BT2.1","BTF1","BTN2.1"],"Ensembl":"ENSG00000112763","Gene description":"Butyrophilin subfamily 2 member A1","Uniprot":["Q7KYR7"],"Chromosome":"6","Position":"26457904-26476621","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019208"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA019208":"AB_1845492"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.90e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.52e-5"}},{"Gene":"BTN2A2","Gene synonym":["BT2.2","BTF2","BTN2.2"],"Ensembl":"ENSG00000124508","Gene description":"Butyrophilin subfamily 2 member A2","Uniprot":["Q8WVV5"],"Chromosome":"6","Position":"26383096-26394874","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"45.1","Langerhans cells":"29.7","Plasma cells":"29.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"72.6"},"RNA tissue cell type enrichment":["Lung - NK-cells (Lung)","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051504"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA051504":"AB_2681510"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"}},{"Gene":"BTN3A1","Gene synonym":["BT3.1","BTF5","BTN3.1","CD277"],"Ensembl":"ENSG00000026950","Gene description":"Butyrophilin subfamily 3 member A1","Uniprot":["O00481"],"Chromosome":"6","Position":"26402237-26415208","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"72.3","Plasma cells":"33.1","T-cells":"41.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - T-cells","Heart muscle - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012565"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA012565":"AB_1845494"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.81e-4"}},{"Gene":"BTN3A2","Gene synonym":["BTN3.2"],"Ensembl":"ENSG00000186470","Gene description":"Butyrophilin subfamily 3 member A2","Uniprot":["P78410"],"Chromosome":"6","Position":"26365159-26378320","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"88.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"184.1","T-cells":"107.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019392"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB019392":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-3"}},{"Gene":"BTN3A3","Gene synonym":["BTF3","BTN3.3"],"Ensembl":"ENSG00000111801","Gene description":"Butyrophilin subfamily 3 member A3","Uniprot":["O00478"],"Chromosome":"6","Position":"26440472-26453415","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"30.7","Plasma cells":"23.7","T-cells":"23.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007904","HPA011871"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007904":"AB_1078307","HPA011871":"AB_1845496"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.80e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.42e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-3"}},{"Gene":"BTNL2","Gene synonym":["BTL-II","BTN7","HSBLMHC1"],"Ensembl":"ENSG00000204290","Gene description":"Butyrophilin like 2","Uniprot":["Q9UIR0"],"Chromosome":"6","Position":"32393963-32407128","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"BTNL3","Gene synonym":["BTN9.1","BTNLR"],"Ensembl":"ENSG00000168903","Gene description":"Butyrophilin like 3","Uniprot":["Q6UXE8"],"Chromosome":"5","Position":"180988846-181006727","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"65","RNA tissue specific nTPM":{"intestine":"115.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Distal enterocytes":"82.9","Intestinal goblet cells":"54.0","Paneth cells":"46.0","Proximal enterocytes":"170.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"5.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"206","RNA blood cell specific nTPM":{"neutrophil":"22.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"206","RNA blood lineage specific nTPM":{"granulocytes":"22.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"colorectal cancer":"2.5","Gastric cancer":"1.2"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"BTNL8","Gene synonym":["BTN9.2","FLJ21458"],"Ensembl":"ENSG00000113303","Gene description":"Butyrophilin like 8","Uniprot":["Q6UX41"],"Chromosome":"5","Position":"180899077-180950906","Protein class":["Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"intestine":"119.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"62.2","Intestinal goblet cells":"34.7","Paneth cells":"39.5","Proximal enterocytes":"192.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"colorectal cancer":"2.6","liver cancer":"1.5","pancreatic cancer":"2.8","stomach cancer":"3.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"neutrophil":"233.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"221","RNA blood lineage specific nTPM":{"granulocytes":"233.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"colorectal cancer":"3.5","Esophageal cancer":"1.8","Gastric cancer":"3.7","pancreatic cancer":"2.2"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039738"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039738":"AB_2676656"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"}},{"Gene":"BTNL9","Gene synonym":["BTN8","FLJ32535"],"Ensembl":"ENSG00000165810","Gene description":"Butyrophilin like 9","Uniprot":["Q6UXG8"],"Chromosome":"5","Position":"181040225-181061521","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"250.8","breast":"200.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Adipocytes":"805.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"12.8"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043429"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA043429":"AB_10961264"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.51e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"}},{"Gene":"BUB1B","Gene synonym":["Bub1A","BUBR1","MAD3L","SSK1"],"Ensembl":"ENSG00000156970","Gene description":"BUB1 mitotic checkpoint serine\/threonine kinase B","Uniprot":["O60566"],"Chromosome":"15","Position":"40161023-40221123","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle","Cell division","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"17.8","lymphoid tissue":"35.7","testis":"22.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Spermatocytes":"81.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Mitotic cells (Colon)","Heart muscle - Mitotic cells (Heart)","Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Testis - Spermatocytes","Thyroid - Mitotic cells (Thyroid)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008419"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008419":"AB_1078308"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.43e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.56e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.79e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"}},{"Gene":"BVES","Gene synonym":["HBVES","POP1","POPDC1"],"Ensembl":"ENSG00000112276","Gene description":"Blood vessel epicardial substance","Uniprot":["Q8NE79"],"Chromosome":"6","Position":"105096822-105137157","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":["Developmental protein"],"Disease involvement":["Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"27.8","skeletal muscle":"43.9","tongue":"29.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"42.2","Early spermatids":"39.2","Late spermatids":"57.9","Oligodendrocytes":"16.8","Skeletal myocytes":"20.8","Spermatocytes":"23.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Liver - Hepatic stellate cells","Prostate - Smooth muscle cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014788","HPA018176"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA014788":"AB_1845504","HPA018176":"AB_1845503"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-4"}},{"Gene":"BX255925.3","Gene synonym":[],"Ensembl":"ENSG00000284976","Gene description":"Novel RING finger protein","Uniprot":[],"Chromosome":"9","Position":"137217452-137219361","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"36.7","Gastric mucus-secreting cells":"45.3","Proximal enterocytes":"40.9","Suprabasal keratinocytes":"43.5"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"C10orf105","Gene synonym":["FLJ00245"],"Ensembl":"ENSG00000214688","Gene description":"Chromosome 10 open reading frame 105","Uniprot":["Q8TEF2"],"Chromosome":"10","Position":"71711701-71737824","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"34.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"4.3","granulocytes":"1.6","Langerhans cells":"2.3","Late spermatids":"8.4","monocytes":"4.0","Schwann cells":"3.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"1.8","non-classical monocyte":"2.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"}},{"Gene":"C11orf21","Gene synonym":[],"Ensembl":"ENSG00000110665","Gene description":"Chromosome 11 open reading frame 21","Uniprot":["Q9P2W6"],"Chromosome":"11","Position":"2295628-2303049","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"50.4","heart muscle":"20.0","lymphoid tissue":"14.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"69.1","Kupffer cells":"21.8","Langerhans cells":"19.5","monocytes":"54.7","NK-cells":"37.9","T-cells":"15.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Leukemia":"24.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Heart muscle - Cardiomyocytes","Kidney - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037607"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA037607":"AB_10672909"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"}},{"Gene":"C11orf24","Gene synonym":["DM4E3"],"Ensembl":"ENSG00000171067","Gene description":"Chromosome 11 open reading frame 24","Uniprot":["Q96F05"],"Chromosome":"11","Position":"68261338-68272001","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"105.0","Plasma cells":"83.1","Proximal enterocytes":"166.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012411","HPA012748"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA012411":null,"HPA012748":"AB_1845526"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.38e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.05e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-3"}},{"Gene":"C11orf87","Gene synonym":["LOC399947","LOH11CR1A","NEURIM1"],"Ensembl":"ENSG00000185742","Gene description":"Chromosome 11 open reading frame 87","Uniprot":["Q6NUJ2"],"Chromosome":"11","Position":"109422190-109429167","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"15.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Excitatory neurons":"51.7","Horizontal cells":"26.3","Inhibitory neurons":"32.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.7"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"15.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"30","RNA cell line specific nTPM":{"Rhabdoid":"14.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034656"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034656":"AB_10600788"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-6"}},{"Gene":"C12orf43","Gene synonym":["Custos","FLJ12448"],"Ensembl":"ENSG00000157895","Gene description":"Chromosome 12 open reading frame 43","Uniprot":["Q96C57"],"Chromosome":"12","Position":"121000486-121016502","Protein class":["Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046148","HPA061739"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA046148":"AB_10965169","HPA061739":"AB_2684597"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.44e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"C12orf76","Gene synonym":["FLJ40142"],"Ensembl":"ENSG00000174456","Gene description":"Chromosome 12 open reading frame 76","Uniprot":[],"Chromosome":"12","Position":"110027028-110073634","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"77.2","choroid plexus":"44.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"164.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"60.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039713"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA039713":"AB_2676640"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.44e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.74e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"}},{"Gene":"C14orf132","Gene synonym":["C14orf88"],"Ensembl":"ENSG00000227051","Gene description":"Chromosome 14 open reading frame 132","Uniprot":["Q9NPU4"],"Chromosome":"14","Position":"96039362-96093971","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"74.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"95.8","Alveolar cells type 2":"40.2","Basal prostatic cells":"57.3","Bipolar cells":"48.3","Endometrial ciliated cells":"61.7","Horizontal cells":"43.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"12.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"63.0"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.54e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.95e-4"}},{"Gene":"C14orf180","Gene synonym":["C14orf77","NRAC"],"Ensembl":"ENSG00000184601","Gene description":"Chromosome 14 open reading frame 180","Uniprot":["Q8N912"],"Chromosome":"14","Position":"104579764-104590515","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"40.8","breast":"26.7","heart muscle":"109.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"2.6","Cardiomyocytes":"10.8","Horizontal cells":"2.6","Skeletal myocytes":"2.0","Smooth muscle cells":"3.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes","Skin - Adipocytes (Skin)","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"C15orf48","Gene synonym":["COXFA4L3","MIR147BHG","NMES1"],"Ensembl":"ENSG00000166920","Gene description":"Chromosome 15 open reading frame 48","Uniprot":["Q9C002"],"Chromosome":"15","Position":"45430579-45448761","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"924.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"4259.0","Enteroendocrine cells":"1487.4","Exocrine glandular cells":"2517.0","Intestinal goblet cells":"1612.9","Langerhans cells":"2589.5","Paneth cells":"2190.0","Proximal enterocytes":"3096.4","Undifferentiated cells":"1588.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.3","intermediate monocyte":"1.6","myeloid DC":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bile duct cancer":"233.1","Bladder cancer":"85.8","colorectal cancer":"78.8","Gallbladder cancer":"93.9","head and neck cancer":"265.5","Kidney cancer":"230.5","lung cancer":"117.7","pancreatic cancer":"218.7","Rhabdoid":"124.3"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Stomach - Gastric mucous cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012943"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012943":"AB_2668774"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"}},{"Gene":"C16orf54","Gene synonym":["FLJ35681"],"Ensembl":"ENSG00000185905","Gene description":"Chromosome 16 open reading frame 54","Uniprot":["Q6UWD8"],"Chromosome":"16","Position":"29742463-29745990","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"41.4","lymphoid tissue":"21.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"33.4","dendritic cells":"38.9","Kupffer cells":"28.7","monocytes":"36.6","NK-cells":"73.7","Plasma cells":"33.6","T-cells":"50.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"14.6","Myeloma":"8.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060546"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060546":"AB_2684317"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"}},{"Gene":"C16orf89","Gene synonym":["MGC45438"],"Ensembl":"ENSG00000153446","Gene description":"Chromosome 16 open reading frame 89","Uniprot":["Q6UX73"],"Chromosome":"16","Position":"5044122-5066110","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"108.3","thyroid gland":"228.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 2":"261.4","Club cells":"66.2","Distal tubular cells":"77.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"lung cancer":"64.7","thyroid cancer":"145.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"thyroid cancer":"13.9"},"RNA tissue cell type enrichment":["Colon - Fibroblasts","Lung - Alveolar cells type 2","Prostate - Fibroblasts","Stomach - Chief cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013613","HPA016934"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013613":"AB_1845584","HPA016934":"AB_2732417"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-3"}},{"Gene":"C16orf91","Gene synonym":["CCSMST1","gs103","URLC5"],"Ensembl":"ENSG00000174109","Gene description":"Chromosome 16 open reading frame 91","Uniprot":["Q4G0I0"],"Chromosome":"16","Position":"1419752-1420756","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"}},{"Gene":"C16orf92","Gene synonym":["FLJ25404"],"Ensembl":"ENSG00000167194","Gene description":"Chromosome 16 open reading frame 92","Uniprot":["Q96LL3"],"Chromosome":"16","Position":"30023198-30027736","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fertilization"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.7","retina":"35.8","testis":"15.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"35","RNA single cell type specific nTPM":{"Early spermatids":"110.9","Late spermatids":"47.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"6.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lung cancer":"1.8","Neuroblastoma":"7.2"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"C16orf95","Gene synonym":[],"Ensembl":"ENSG00000260456","Gene description":"Chromosome 16 open reading frame 95","Uniprot":["Q9H693"],"Chromosome":"16","Position":"87083562-87317420","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"testis":"101.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Early spermatids":"83.8","Late spermatids":"75.9","Spermatocytes":"79.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040850","HPA067924"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA040850":"AB_10794882","HPA067924":"AB_2685924"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"C17orf113","Gene synonym":[],"Ensembl":"ENSG00000267221","Gene description":"Chromosome 17 open reading frame 113","Uniprot":["A0A1B0GUU1"],"Chromosome":"17","Position":"42038232-42050601","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"5.8","Muller glia cells":"3.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.24e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"}},{"Gene":"C17orf78","Gene synonym":["FLJ39647"],"Ensembl":"ENSG00000278505","Gene description":"Chromosome 17 open reading frame 78","Uniprot":["Q8N4C9"],"Chromosome":"17","Position":"37375985-37392708","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"95","RNA tissue specific nTPM":{"intestine":"127.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Proximal enterocytes":"234.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"colorectal cancer":"0.8","stomach cancer":"1.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"}},{"Gene":"C17orf80","Gene synonym":["FLJ20721","HLC-8","MIG3","SPEP1"],"Ensembl":"ENSG00000141219","Gene description":"Chromosome 17 open reading frame 80","Uniprot":["Q9BSJ5"],"Chromosome":"17","Position":"73232233-73248947","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"175.8","Late spermatids":"112.0","Spermatocytes":"55.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012896"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA012896":"AB_1850766"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.43e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.02e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"C18orf32","Gene synonym":["FLJ23458"],"Ensembl":"ENSG00000177576","Gene description":"Chromosome 18 open reading frame 32","Uniprot":["Q8TCD1"],"Chromosome":"18","Position":"49477243-49487252","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"138.4","Late spermatids":"230.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040921"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA040921":"AB_10795423"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.89e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"}},{"Gene":"C19orf18","Gene synonym":["MGC41906"],"Ensembl":"ENSG00000177025","Gene description":"Chromosome 19 open reading frame 18","Uniprot":["Q8NEA5"],"Chromosome":"19","Position":"57958437-57974534","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"12.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"159.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014527","HPA079195"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA014527":"AB_1845612","HPA079195":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.07e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"}},{"Gene":"C19orf25","Gene synonym":["FLJ36666"],"Ensembl":"ENSG00000119559","Gene description":"Chromosome 19 open reading frame 25","Uniprot":["Q9UFG5"],"Chromosome":"19","Position":"1461143-1479219","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050270","HPA067491"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA050270":"AB_2681069","HPA067491":"AB_2685849"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.08e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.81e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.21e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.20e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"}},{"Gene":"C19orf38","Gene synonym":["HIDE1"],"Ensembl":"ENSG00000214212","Gene description":"Chromosome 19 open reading frame 38","Uniprot":["A8MVS5"],"Chromosome":"19","Position":"10836575-10869790","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"98.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"64.7","Kupffer cells":"114.6","Macrophages":"50.5","monocytes":"180.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"20","RNA blood cell specific nTPM":{"classical monocyte":"282.3","eosinophil":"169.4","intermediate monocyte":"312.5","myeloid DC":"162.2","neutrophil":"230.1","non-classical monocyte":"392.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"dendritic cells":"162.2","granulocytes":"230.1","monocytes":"392.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"11.1","lymphoma":"5.5","Myeloma":"5.9"},"RNA tissue cell type enrichment":["Kidney - Macrophages","Lung - Neutrophil_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012150","HPA055027"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Golgi apparatus","Plasma membrane"],"Antibody RRID":{"HPA012150":"AB_10603448","HPA055027":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.43e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.75e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"}},{"Gene":"C1GALT1C1","Gene synonym":["C1GALT2","COSMC"],"Ensembl":"ENSG00000171155","Gene description":"C1GALT1 specific chaperone 1","Uniprot":["Q96EU7"],"Chromosome":"X","Position":"120625674-120630054","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"107.9","Ionocytes":"93.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010666","HPA015632"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA010666":null,"HPA015632":"AB_1845625"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.66e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"}},{"Gene":"C1GALT1C1L","Gene synonym":[],"Ensembl":"ENSG00000223658","Gene description":"C1GALT1 specific chaperone 1 like","Uniprot":["P0DN25"],"Chromosome":"2","Position":"43675151-43676429","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"7.5","Muller glia cells":"4.9","Spermatocytes":"17.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-2"}},{"Gene":"C1orf159","Gene synonym":["FLJ20584"],"Ensembl":"ENSG00000131591","Gene description":"Chromosome 1 open reading frame 159","Uniprot":["Q96HA4"],"Chromosome":"1","Position":"1081818-1116361","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"22.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"61.6","Late spermatids":"125.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010019","HPA075399"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli rim","Mitotic chromosome","Intermediate filaments"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoli rim","Mitotic chromosome"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"HPA010019":"AB_1078885","HPA075399":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.58e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.77e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.62e-4"}},{"Gene":"C1orf162","Gene synonym":["MGC24133"],"Ensembl":"ENSG00000143110","Gene description":"Chromosome 1 open reading frame 162","Uniprot":["Q8NEQ5"],"Chromosome":"1","Position":"111473792-111478512","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"115.0","lymphoid tissue":"134.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"361.1","Kupffer cells":"668.2","Langerhans cells":"256.1","Macrophages":"441.8","monocytes":"553.5","NK-cells":"193.9","Schwann cells":"450.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"20.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Prostate - Macrophages","Skin - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026988"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA026988":"AB_10600887"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"}},{"Gene":"C1orf167","Gene synonym":["DKFZp434E1410","RP11-56N19.2"],"Ensembl":"ENSG00000215910","Gene description":"Chromosome 1 open reading frame 167","Uniprot":["Q5SNV9"],"Chromosome":"1","Position":"11761787-11789585","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"47","RNA tissue specific nTPM":{"testis":"28.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"86.3","Alveolar cells type 2":"39.3","Early spermatids":"15.0","Late spermatids":"20.9","Skeletal myocytes":"21.8","Spermatocytes":"15.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"lymphoma":"1.4","Myeloma":"1.4"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039114"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039114":"AB_10673606"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"}},{"Gene":"C1orf185","Gene synonym":["FLJ27485"],"Ensembl":"ENSG00000204006","Gene description":"Chromosome 1 open reading frame 185","Uniprot":["Q5T7R7"],"Chromosome":"1","Position":"51102221-51148086","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"138","RNA tissue specific nTPM":{"testis":"25.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"693.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"C1orf210","Gene synonym":["MGC52423","TEMP"],"Ensembl":"ENSG00000253313","Gene description":"Chromosome 1 open reading frame 210","Uniprot":["Q8IVY1"],"Chromosome":"1","Position":"43281877-43285617","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"43.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"114.7","Enteroendocrine cells":"47.4","Paneth cells":"62.9","Proximal enterocytes":"136.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"basophil":"2.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"granulocytes":"2.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Colon enterocytes","Liver - Hepatocytes","Lung - Alveolar cells type 2","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013788"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":null,"Antibody RRID":{"HPA013788":"AB_1845637"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"}},{"Gene":"C1orf43","Gene synonym":["DKFZp586G1722","NICE-3"],"Ensembl":"ENSG00000143612","Gene description":"Chromosome 1 open reading frame 43","Uniprot":["Q9BWL3"],"Chromosome":"1","Position":"154206696-154220637","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010725"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA010725":"AB_1078341"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.57e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"C1QTNF6","Gene synonym":["CTRP6","ZACRP6"],"Ensembl":"ENSG00000133466","Gene description":"C1q and TNF related 6","Uniprot":["Q9BXI9"],"Chromosome":"22","Position":"37180166-37199385","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"31.7","placenta":"29.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"480.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002042"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Secreted to blood","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":354000000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA002042":"AB_1078342"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.60e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"}},{"Gene":"C2","Gene synonym":[],"Ensembl":"ENSG00000166278","Gene description":"Complement C2","Uniprot":["P06681"],"Chromosome":"6","Position":"31897785-31945672","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Age-related macular degeneration","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"477.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"189.1","Hepatocytes":"327.6","Hofbauer cells":"244.4","Kupffer cells":"99.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"100.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"21.1","non-classical monocyte":"25.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"35","RNA blood lineage specific nTPM":{"monocytes":"25.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"liver cancer":"11.7","Myeloma":"15.4","thyroid cancer":"4.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Liver - Hepatocytes","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016775"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016775":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.64e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"}},{"Gene":"C20orf141","Gene synonym":["dJ860F19.4"],"Ensembl":"ENSG00000258713","Gene description":"Chromosome 20 open reading frame 141","Uniprot":["Q9NUB4"],"Chromosome":"20","Position":"2814987-2815833","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"79","RNA tissue specific nTPM":{"testis":"130.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Late spermatids":"4752.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"1.2"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"C20orf173","Gene synonym":["dJ477O4.4"],"Ensembl":"ENSG00000125975","Gene description":"Chromosome 20 open reading frame 173","Uniprot":["Q96LM9"],"Chromosome":"20","Position":"35523186-35529652","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"45","RNA tissue specific nTPM":{"testis":"35.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"113","RNA single cell type specific nTPM":{"Early spermatids":"247.9","Late spermatids":"218.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076859"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"HPA076859":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"C20orf194","Gene synonym":["DKFZp434N061"],"Ensembl":"ENSG00000088854","Gene description":"Chromosome 20 open reading frame 194","Uniprot":["Q5TEA3"],"Chromosome":"20","Position":"3249306-3407669","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"219.8","Excitatory neurons":"202.6","Inhibitory neurons":"159.4","Oligodendrocyte precursor cells":"130.0","Oligodendrocytes":"180.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052103","HPA067418"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoli fibrillar center","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA052103":"AB_2681727","HPA067418":"AB_2685835"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.68e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.68e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"}},{"Gene":"C2CD2L","Gene synonym":["KIAA0285","TMEM24"],"Ensembl":"ENSG00000172375","Gene description":"C2CD2 like","Uniprot":["O14523"],"Chromosome":"11","Position":"119102198-119118544","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"29.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011044","HPA075369"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA011044":"AB_2668414","HPA075369":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.92e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.75e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"}},{"Gene":"C2CD5","Gene synonym":["CDP138","KIAA0528"],"Ensembl":"ENSG00000111731","Gene description":"C2 calcium dependent domain containing 5","Uniprot":["Q86YS7"],"Chromosome":"12","Position":"22448583-22544546","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"241.1","Inhibitory neurons":"247.7","Oligodendrocyte precursor cells":"143.0","Oligodendrocytes":"97.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"testis cancer":"39.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046194"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA046194":"AB_10965327"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"}},{"Gene":"C2orf16","Gene synonym":["DKFZp434G118"],"Ensembl":"ENSG00000221843","Gene description":"Chromosome 2 open reading frame 16","Uniprot":["Q68DN1"],"Chromosome":"2","Position":"27537386-27582721","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"testis":"21.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"35","RNA single cell type specific nTPM":{"Early spermatids":"391.8","Late spermatids":"123.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052136","HPA056962"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA052136":"AB_2681742","HPA056962":"AB_2683290"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"}},{"Gene":"C2orf74","Gene synonym":["LOC339804"],"Ensembl":"ENSG00000237651","Gene description":"Chromosome 2 open reading frame 74","Uniprot":["A8MZ97"],"Chromosome":"2","Position":"61145068-61164828","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"15.5","Early spermatids":"16.1","Proximal tubular cells":"14.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026826"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA026826":"AB_10671091"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"}},{"Gene":"C2orf81","Gene synonym":["hCG40743","LOC388963"],"Ensembl":"ENSG00000284308","Gene description":"Chromosome 2 open reading frame 81","Uniprot":["A6NN90"],"Chromosome":"2","Position":"74414176-74421591","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"27.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"41.7","Late spermatids":"34.5","Respiratory ciliated cells":"32.1","Spermatocytes":"15.7"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"13.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049564","HPA054835"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA049564":null,"HPA054835":"AB_2682620"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"C2orf92","Gene synonym":["LINC01125"],"Ensembl":"ENSG00000228486","Gene description":"Chromosome 2 open reading frame 92","Uniprot":["A0A1B0GVN3"],"Chromosome":"2","Position":"97664217-97703064","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"11.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Early spermatids":"252.9","Late spermatids":"81.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-5"}},{"Gene":"C3AR1","Gene synonym":["AZ3B","C3AR"],"Ensembl":"ENSG00000171860","Gene description":"Complement C3a receptor 1","Uniprot":["Q16581"],"Chromosome":"12","Position":"8056844-8066359","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Chemotaxis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"40.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"granulocytes":"50.8","Hofbauer cells":"173.4","Kupffer cells":"115.3","Macrophages":"148.5","monocytes":"107.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"898.6","eosinophil":"450.8","intermediate monocyte":"273.6","non-classical monocyte":"371.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"granulocytes":"898.6","monocytes":"371.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"5.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009405"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009405":"AB_2066739"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"}},{"Gene":"C3orf18","Gene synonym":["G20"],"Ensembl":"ENSG00000088543","Gene description":"Chromosome 3 open reading frame 18","Uniprot":["Q9UK00"],"Chromosome":"3","Position":"50558025-50571027","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"32.8","Early spermatids":"47.9","Late spermatids":"69.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"2.2","NK-cells":"2.0","T-cells":"6.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"cerebellum":"28.2","olfactory bulb":"27.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012105"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA012105":"AB_1845717"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.80e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"}},{"Gene":"C3orf33","Gene synonym":["AC3-33","FLJ31139"],"Ensembl":"ENSG00000174928","Gene description":"Chromosome 3 open reading frame 33","Uniprot":["Q6P1S2"],"Chromosome":"3","Position":"155762617-155806278","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"13.3","Excitatory neurons":"14.7","Inhibitory neurons":"14.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037663"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037663":"AB_10672610"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.48e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"}},{"Gene":"C3orf52","Gene synonym":["FLJ23186","TTMP"],"Ensembl":"ENSG00000114529","Gene description":"Chromosome 3 open reading frame 52","Uniprot":["Q5BVD1"],"Chromosome":"3","Position":"112086335-112131004","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"17.4","skin 1":"26.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"48.6","Basal squamous epithelial cells":"51.1","Gastric mucus-secreting cells":"57.8","Intestinal goblet cells":"61.5","Syncytiotrophoblasts":"82.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Cholangiocyte","Lung - Alveolar cells type 2","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007678","HPA008119","HPA011968"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007678":null,"HPA008119":"AB_1848824","HPA011968":"AB_1848826"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.85e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"}},{"Gene":"C3orf80","Gene synonym":[],"Ensembl":"ENSG00000180044","Gene description":"Chromosome 3 open reading frame 80","Uniprot":["F5H4A9"],"Chromosome":"3","Position":"160225422-160228213","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"5.5","esophagus":"4.6","intestine":"8.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"4.3","Enteroendocrine cells":"7.5","Excitatory neurons":"23.3","Horizontal cells":"4.5","Inhibitory neurons":"6.2","Oligodendrocytes":"5.6","Spermatocytes":"6.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"8.9"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047439"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047439":"AB_10965171"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"}},{"Gene":"C4orf3","Gene synonym":["ALN","HCVFTP1"],"Ensembl":"ENSG00000164096","Gene description":"Chromosome 4 open reading frame 3","Uniprot":["Q8WVX3"],"Chromosome":"4","Position":"119296419-119304445","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"995.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026907"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA026907":"AB_10600760"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.46e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"}},{"Gene":"C5AR1","Gene synonym":["C5A","C5AR","C5R1","CD88"],"Ensembl":"ENSG00000197405","Gene description":"Complement C5a receptor 1","Uniprot":["P21730"],"Chromosome":"19","Position":"47290023-47322066","Protein class":["CD markers","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Chemotaxis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"125.5","lymphoid tissue":"84.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"221.3","Kupffer cells":"524.8","Macrophages":"438.4","monocytes":"1802.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"394.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"42","RNA blood lineage specific nTPM":{"granulocytes":"394.0","monocytes":"115.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Colon - Neutrophils","Heart muscle - Macrophages","Kidney - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002720","HPA014520","HPA048012"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB002720":null,"HPA014520":"AB_1846337","HPA048012":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.71e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.55e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.99e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"}},{"Gene":"C5AR2","Gene synonym":["C5L2","GPR77"],"Ensembl":"ENSG00000134830","Gene description":"Complement component 5a receptor 2","Uniprot":["Q9P296"],"Chromosome":"19","Position":"47332175-47347329","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"14.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Macrophages":"45.1","monocytes":"141.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"3.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"17.8","eosinophil":"11.9","neutrophil":"33.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"33.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"6.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016629"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016629":"AB_1849312"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-3"}},{"Gene":"C5orf15","Gene synonym":["HTGN29","KCT2"],"Ensembl":"ENSG00000113583","Gene description":"Chromosome 5 open reading frame 15","Uniprot":["Q8NC54"],"Chromosome":"5","Position":"133955510-133968674","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011951","HPA039165"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA011951":"AB_2668584","HPA039165":"AB_10795580"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"}},{"Gene":"C5orf22","Gene synonym":["FLJ11193"],"Ensembl":"ENSG00000082213","Gene description":"Chromosome 5 open reading frame 22","Uniprot":["Q49AR2"],"Chromosome":"5","Position":"31532287-31555053","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"28.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"28.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043062"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA043062":"AB_10795766"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.55e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"}},{"Gene":"C6orf120","Gene synonym":["bA160E12.4"],"Ensembl":"ENSG00000185127","Gene description":"Chromosome 6 open reading frame 120","Uniprot":["Q7Z4R8"],"Chromosome":"6","Position":"169702190-169704856","Protein class":["Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"115.2","Late spermatids":"277.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039626"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"620000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039626":"AB_10673361"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.52e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.37e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-3"}},{"Gene":"C6orf136","Gene synonym":["Em:AB023049.8"],"Ensembl":"ENSG00000204564","Gene description":"Chromosome 6 open reading frame 136","Uniprot":["Q5SQH8"],"Chromosome":"6","Position":"30647039-30653210","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"86.0","Proximal enterocytes":"108.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046804"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046804":"AB_2679815"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.16e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.51e-4"}},{"Gene":"C6orf47","Gene synonym":["D6S53E","G4"],"Ensembl":"ENSG00000204439","Gene description":"Chromosome 6 open reading frame 47","Uniprot":["O95873"],"Chromosome":"6","Position":"31658298-31660778","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045281"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA045281":"AB_10961000"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-3"}},{"Gene":"C6orf89","Gene synonym":["BRAP","FLJ25357"],"Ensembl":"ENSG00000198663","Gene description":"Chromosome 6 open reading frame 89","Uniprot":["Q6UWU4"],"Chromosome":"6","Position":"36871870-36928964","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"258.8","Late spermatids":"732.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012548"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012548":"AB_1845748"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-3"}},{"Gene":"C7orf25","Gene synonym":["MGC2821"],"Ensembl":"ENSG00000136197","Gene description":"Chromosome 7 open reading frame 25","Uniprot":["Q9BPX7"],"Chromosome":"7","Position":"42908726-42912305","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"3.9","Excitatory neurons":"4.6","Inhibitory neurons":"4.6","Oligodendrocytes":"7.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"36.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"granulocytes":"36.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020120","HPA049635"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA020120":"AB_1845755","HPA049635":"AB_2680837"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"}},{"Gene":"C7orf61","Gene synonym":["IMAGE:4839025"],"Ensembl":"ENSG00000185955","Gene description":"Chromosome 7 open reading frame 61","Uniprot":["Q8IZ16"],"Chromosome":"7","Position":"100456620-100464260","Protein class":["Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"testis":"68.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"25","RNA single cell type specific nTPM":{"Early spermatids":"638.9","Late spermatids":"358.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"3.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060395"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA060395":"AB_2684274"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"}},{"Gene":"C8orf58","Gene synonym":["FLJ34715"],"Ensembl":"ENSG00000241852","Gene description":"Chromosome 8 open reading frame 58","Uniprot":["Q8NAV2"],"Chromosome":"8","Position":"22599599-22604150","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"28.7","Extravillous trophoblasts":"34.1","Syncytiotrophoblasts":"53.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024667","HPA028286"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA024667":"AB_1845783","HPA028286":"AB_1845784"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"}},{"Gene":"C9orf57","Gene synonym":[],"Ensembl":"ENSG00000204669","Gene description":"Chromosome 9 open reading frame 57","Uniprot":["Q5W0N0"],"Chromosome":"9","Position":"72051376-72072721","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"37","RNA tissue specific nTPM":{"testis":"13.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"3.4","Late spermatids":"1.5","Sertoli cells":"2.8","Spermatocytes":"10.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"C9orf72","Gene synonym":["DENND9","DENNL72","MGC23980"],"Ensembl":"ENSG00000147894","Gene description":"C9orf72-SMCR8 complex subunit","Uniprot":["Q96LT7"],"Chromosome":"9","Position":"27535640-27573866","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Amyotrophic lateral sclerosis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"152.8","monocytes":"222.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"24.3","classical monocyte":"32.0","intermediate monocyte":"44.7","myeloid DC":"25.2","neutrophil":"34.3","non-classical monocyte":"36.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"25.2","granulocytes":"34.3","monocytes":"44.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023873"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Midbody ring","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Midbody ring"],"Antibody RRID":{"HPA023873":"AB_1845834"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"}},{"Gene":"CA10","Gene synonym":["CA-RPX","CARPX","HUCEP-15"],"Ensembl":"ENSG00000154975","Gene description":"Carbonic anhydrase 10","Uniprot":["Q9NS85"],"Chromosome":"17","Position":"51630313-52160017","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"54.9","cervix":"21.8","retina":"44.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"1539.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"4.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"1.7","thyroid cancer":"4.1"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Podocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054825","HPA057837"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA054825":"AB_2682617","HPA057837":"AB_2683542"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"CA12","Gene synonym":["HsT18816"],"Ensembl":"ENSG00000074410","Gene description":"Carbonic anhydrase 12","Uniprot":["O43570"],"Chromosome":"15","Position":"63321378-63381846","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"290.2","skin 1":"142.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"147.1","Basal squamous epithelial cells":"125.7","Distal enterocytes":"297.9","Intestinal goblet cells":"121.0","Paneth cells":"131.6","Squamous epithelial cells":"184.0","Suprabasal keratinocytes":"194.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"109.3"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"42.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"197.4"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008773","CAB025181","CAB062549","CAB068179","HPA073203"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"52000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025181":null,"CAB062549":"AB_2665617","CAB068179":"AB_2665616","HPA008773":"AB_1078394","HPA073203":"AB_2686580"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.80e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"}},{"Gene":"CA14","Gene synonym":[],"Ensembl":"ENSG00000118298","Gene description":"Carbonic anhydrase 14","Uniprot":["Q9ULX7"],"Chromosome":"1","Position":"150257251-150265078","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"33.3","retina":"39.4","skeletal muscle":"33.7","tongue":"47.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"57.3","Melanocytes":"69.7","Muller glia cells":"153.9","Oligodendrocytes":"24.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"melanoma":"23.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Rhabdoid":"28.3","skin cancer":"22.6","testis cancer":"14.6"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Skeletal muscle - Skeletal myocytes","Skin - Melanocytes","Testis - Peritubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008482"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA008482":"AB_1078395"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.47e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"}},{"Gene":"CA4","Gene synonym":["CAIV","Car4","RP17"],"Ensembl":"ENSG00000167434","Gene description":"Carbonic anhydrase 4","Uniprot":["P22748"],"Chromosome":"17","Position":"60149942-60170899","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["Disease variant","FDA approved drug targets","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"263.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Paneth cells":"4367.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"7.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"99.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"995","RNA blood lineage specific nTPM":{"granulocytes":"99.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Brain cancer":"5.0","liver cancer":"7.5","prostate cancer":"8.2","Rhabdoid":"2.8"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Colon - Colon enterocytes"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebellum":"300.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011089","HPA017258"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA011089":"AB_1845996","HPA017258":"AB_1845997"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"}},{"Gene":"CA9","Gene synonym":["CAIX","MN"],"Ensembl":"ENSG00000107159","Gene description":"Carbonic anhydrase 9","Uniprot":["Q16790"],"Chromosome":"9","Position":"35673918-35681159","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"stomach 1":"289.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"259.4","Early spermatids":"174.3","Gastric mucus-secreting cells":"254.6","Late spermatids":"59.4","Thymic epithelial cells":"60.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"85.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"9","RNA brain regional specific nTPM":{"cerebellum":"5.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"87.8","Sarcoma":"51.7"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Liver - Cholangiocyte","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"12.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005100","CAB017107","HPA055207"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB005100":"AB_2066539","CAB017107":null,"HPA055207":"AB_2682738"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.71e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.22e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.50e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"}},{"Gene":"CABLES1","Gene synonym":["FLJ35924","HsT2563"],"Ensembl":"ENSG00000134508","Gene description":"Cdk5 and Abl enzyme substrate 1","Uniprot":["Q8TDN4"],"Chromosome":"18","Position":"23134564-23260467","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division"],"Molecular function":["Cyclin"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"70.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"250.2","Oligodendrocyte precursor cells":"156.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"melanoma":"38.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"NK-cell":"1.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"NK-cells":"1.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Fibroblasts","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073649"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA073649":"AB_2732233"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.71e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-2"}},{"Gene":"CABLES2","Gene synonym":["C20orf150","dJ908M14.2","ik3-2"],"Ensembl":"ENSG00000149679","Gene description":"Cdk5 and Abl enzyme substrate 2","Uniprot":["Q9BTV7"],"Chromosome":"20","Position":"62388632-62407285","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division"],"Molecular function":["Cyclin"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"31.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"57.2","Late spermatids":"26.8","Spermatocytes":"19.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043597"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA043597":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.26e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"}},{"Gene":"CABP7","Gene synonym":["MGC57793"],"Ensembl":"ENSG00000100314","Gene description":"Calcium binding protein 7","Uniprot":["Q86V35"],"Chromosome":"22","Position":"29720003-29731833","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"38.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1.2","Inhibitory neurons":"1.0","Muller glia cells":"1.1","Oligodendrocyte precursor cells":"1.4","Rod photoreceptor cells":"1.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"2.3","ovarian cancer":"1.0","pancreatic cancer":"3.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"3.5"},"RNA tissue cell type enrichment":["Pancreas - Beta cells","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"cerebellum":"74.4","hippocampal formation":"204.8","midbrain":"60.3","pons and medulla":"110.0"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"51.0"},"Antibody":["HPA016439"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 26: NCI-H716 - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016439":"AB_2669357"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"}},{"Gene":"CACFD1","Gene synonym":["C9orf7","D9S2135","flower"],"Ensembl":"ENSG00000160325","Gene description":"Calcium channel flower domain containing 1","Uniprot":["Q9UGQ2"],"Chromosome":"9","Position":"133459965-133470848","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"58.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"60.1","Gastric mucus-secreting cells":"57.8","Intestinal goblet cells":"48.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"3.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"2.0","granulocytes":"3.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015280"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015280":"AB_1845833"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.83e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"}},{"Gene":"CACHD1","Gene synonym":["KIAA1573","VWCD1"],"Ensembl":"ENSG00000158966","Gene description":"Cache domain containing 1","Uniprot":["Q5VU97"],"Chromosome":"1","Position":"64470129-64693058","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"274.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"35.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017202"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"310000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA017202":"AB_1852423"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"}},{"Gene":"CACNA1A","Gene synonym":["APCA","CACNL1A4","Cav2.1","EA2","FHM","HPCA","MHP","MHP1","SCA6"],"Ensembl":"ENSG00000141837","Gene description":"Calcium voltage-gated channel subunit alpha1 A","Uniprot":["O00555"],"Chromosome":"19","Position":"13206442-13633025","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"99.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Bipolar cells":"148.0","Enteroendocrine cells":"232.2","Excitatory neurons":"313.9","Horizontal cells":"437.7","Inhibitory neurons":"363.4","Oligodendrocyte precursor cells":"260.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"99.3","cerebral cortex":"30.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"8.0","Rhabdoid":"8.0"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells","Skeletal muscle - Smooth muscle cells","Stomach - Gastric enteroendocrine cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064258","HPA068138","HPA071902"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Uncertain","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA064258":"AB_2685229","HPA068138":null,"HPA071902":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.32e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"}},{"Gene":"CACNA1B","Gene synonym":["CACNL1A5","CACNN","Cav2.2"],"Ensembl":"ENSG00000148408","Gene description":"Calcium voltage-gated channel subunit alpha1 B","Uniprot":["Q00975"],"Chromosome":"9","Position":"137877782-138124624","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.2","pituitary gland":"6.8","testis":"5.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Excitatory neurons":"383.1","Inhibitory neurons":"323.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.2"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"amygdala":"5.9","basal ganglia":"7.8","cerebral cortex":"10.2","hippocampal formation":"3.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"14.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022919","HPA044347"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA022919":null,"HPA044347":"AB_10960837"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"}},{"Gene":"CACNA1C","Gene synonym":["CACH2","CACN2","CACNL1A1","Cav1.2","CCHL1A1","LQT8","TS"],"Ensembl":"ENSG00000151067","Gene description":"Calcium voltage-gated channel subunit alpha1 C","Uniprot":["Q13936"],"Chromosome":"12","Position":"1970786-2697950","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Host-virus interaction","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Ion channel","Voltage-gated channel"],"Disease involvement":["Autism","Autism spectrum disorder","Brugada syndrome","Disease variant","FDA approved drug targets","Long QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"20.7","heart muscle":"27.1","intestine":"29.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"598.2","Inhibitory neurons":"465.5","Oligodendrocyte precursor cells":"186.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"2.9"},"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039796","CAB079031"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079031":null,"HPA039796":"AB_10673019"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"}},{"Gene":"CACNA1D","Gene synonym":["CACH3","CACN4","CACNL1A2","Cav1.3","CCHL1A2"],"Ensembl":"ENSG00000157388","Gene description":"Calcium voltage-gated channel subunit alpha1 D","Uniprot":["Q01668"],"Chromosome":"3","Position":"53328963-53813733","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"247.6","Horizontal cells":"114.1","Inhibitory neurons":"345.8","Microglial cells":"123.1","Oligodendrocyte precursor cells":"189.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"5.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"basophil":"3.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"granulocytes":"3.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Skeletal muscle - Fibroblasts","Testis - Peritubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020215"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA020215":"AB_1845860"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.34e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-3"}},{"Gene":"CACNA1E","Gene synonym":["BII","CACH6","CACNL1A6","Cav2.3"],"Ensembl":"ENSG00000198216","Gene description":"Calcium voltage-gated channel subunit alpha1 E","Uniprot":["Q15878"],"Chromosome":"1","Position":"181317690-181808084","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"brain":"42.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"185.8","Inhibitory neurons":"112.9","Oligodendrocyte precursor cells":"70.8","Oligodendrocytes":"32.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"1.9","lymphoma":"1.8","prostate cancer":"2.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Proximal tubular cells","Lung - Neutrophil_2","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042515","CAB079032"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Actin filaments","Cytosol"],"Antibody RRID":{"CAB079032":null,"HPA042515":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"}},{"Gene":"CACNA1F","Gene synonym":["AIED","Cav1.4","CORDX3","CSNB2","CSNB2A","CSNBX2","JM8","JMC8","OA2"],"Ensembl":"ENSG00000102001","Gene description":"Calcium voltage-gated channel subunit alpha1 F","Uniprot":["O60840"],"Chromosome":"X","Position":"49205063-49233371","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Cone-rod dystrophy","Congenital stationary night blindness","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"53","RNA tissue specific nTPM":{"retina":"125.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Bipolar cells":"67.4","Cone photoreceptor cells":"74.1","Rod photoreceptor cells":"93.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068379"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA068379":"AB_2732782"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-3"}},{"Gene":"CACNA1G","Gene synonym":["Cav3.1","NBR13"],"Ensembl":"ENSG00000006283","Gene description":"Calcium voltage-gated channel subunit alpha1 G","Uniprot":["O43497"],"Chromosome":"17","Position":"50560715-50627474","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","FDA approved drug targets","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"37.5","cervix":"9.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"155.1","Horizontal cells":"69.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.6","testis cancer":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"7.2"},"RNA tissue cell type enrichment":["Lung - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004714"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004714":"AB_1078368"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"}},{"Gene":"CACNA1H","Gene synonym":["Cav3.2"],"Ensembl":"ENSG00000196557","Gene description":"Calcium voltage-gated channel subunit alpha1 H","Uniprot":["O95180"],"Chromosome":"16","Position":"1153106-1221771","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"107.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"19.3","Enteroendocrine cells":"13.4","Horizontal cells":"12.2","Late spermatids":"14.7","Peritubular cells":"23.1","Sertoli cells":"11.1","Smooth muscle cells":"25.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039125"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA039125":"AB_10795578"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.12e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.78e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"}},{"Gene":"CACNA1I","Gene synonym":["Cav3.3"],"Ensembl":"ENSG00000100346","Gene description":"Calcium voltage-gated channel subunit alpha1 I","Uniprot":["Q9P0X4"],"Chromosome":"22","Position":"39570753-39689735","Protein class":["FDA approved drug targets","Plasma proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"9.7","thyroid gland":"5.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"13.8","Excitatory neurons":"16.6","Horizontal cells":"30.8","Inhibitory neurons":"12.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"2.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"3.0","Rhabdoid":"1.3"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066992"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA066992":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-4"}},{"Gene":"CACNA1S","Gene synonym":["CACNL1A3","Cav1.1","HOKPP","hypoPP","MHS5"],"Ensembl":"ENSG00000081248","Gene description":"Calcium voltage-gated channel subunit alpha1 S","Uniprot":["Q13698"],"Chromosome":"1","Position":"201039512-201112451","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"86","RNA tissue specific nTPM":{"skeletal muscle":"254.9","tongue":"193.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Skeletal myocytes":"107.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"1.2"},"RNA tissue cell type enrichment":["Adipose visceral - Smooth muscle cells","Skeletal muscle - Skeletal myocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.8"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"olfactory bulb":"2.6"},"Antibody":["CAB009507","HPA048892","HPA056815"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009507":"AB_2069576","HPA048892":"AB_2680548","HPA056815":"AB_2683242"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"}},{"Gene":"CACNA2D1","Gene synonym":["CACNA2","CACNL2A","LINC01112","lncRNA-N3","MHS3"],"Ensembl":"ENSG00000153956","Gene description":"Calcium voltage-gated channel auxiliary subunit alpha2delta 1","Uniprot":["P54289"],"Chromosome":"7","Position":"81946444-82443777","Protein class":["FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"78.7","tongue":"98.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"535.3","Inhibitory neurons":"373.7","Oligodendrocyte precursor cells":"342.7","Oligodendrocytes":"625.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"33.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008213","HPA008621"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"390000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008213":"AB_1233654","HPA008621":"AB_1845863"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-4"}},{"Gene":"CACNA2D2","Gene synonym":["KIAA0558"],"Ensembl":"ENSG00000007402","Gene description":"Calcium voltage-gated channel auxiliary subunit alpha2delta 2","Uniprot":["Q9NY47"],"Chromosome":"3","Position":"50362613-50504244","Protein class":["Disease related genes","FDA approved drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"49.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 1":"39.9","Alveolar cells type 2":"121.1","Horizontal cells":"61.5","Inhibitory neurons":"35.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"20.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"26.3","thyroid cancer":"12.8"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Colon enteroendocrine cells","Lung - Alveolar cells type 2","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034771","HPA071829"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9700000","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA034771":"AB_10603555","HPA071829":"AB_2686454"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.62e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.21e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"}},{"Gene":"CACNA2D3","Gene synonym":["HSA272268"],"Ensembl":"ENSG00000157445","Gene description":"Calcium voltage-gated channel auxiliary subunit alpha2delta 3","Uniprot":["Q8IZS8"],"Chromosome":"3","Position":"54122547-55074557","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"15.8","skeletal muscle":"9.9","tongue":"10.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"155.9","Excitatory neurons":"816.8","Inhibitory neurons":"444.3","Oligodendrocyte precursor cells":"304.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"4.1"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Cardiomyocytes","Prostate - Smooth muscle cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030849"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"69000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA030849":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"}},{"Gene":"CACNA2D4","Gene synonym":[],"Ensembl":"ENSG00000151062","Gene description":"Calcium voltage-gated channel auxiliary subunit alpha2delta 4","Uniprot":["Q7Z3S7"],"Chromosome":"12","Position":"1791963-1918666","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"39","RNA tissue specific nTPM":{"retina":"20.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"57.9","Cone photoreceptor cells":"81.0","Hofbauer cells":"33.1","Late spermatids":"127.0","Rod photoreceptor cells":"99.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"2.9","monocytes":"4.4","T-cells":"4.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"8.2","lymphoma":"4.0","Sarcoma":"3.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031952"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031952":"AB_10600798"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"}},{"Gene":"CACNB4","Gene synonym":["EJM4"],"Ensembl":"ENSG00000182389","Gene description":"Calcium voltage-gated channel auxiliary subunit beta 4","Uniprot":["O00305"],"Chromosome":"2","Position":"151832771-152099167","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"16.4","skin 1":"7.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"488.2","Horizontal cells":"108.9","Inhibitory neurons":"461.0","Microglial cells":"133.2","Oligodendrocyte precursor cells":"148.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"3.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"3.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Lung - Alveolar cells type 2","Testis - Sertoli cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015601"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015601":"AB_1845873"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"}},{"Gene":"CACNG1","Gene synonym":["CACNLG"],"Ensembl":"ENSG00000108878","Gene description":"Calcium voltage-gated channel auxiliary subunit gamma 1","Uniprot":["Q06432"],"Chromosome":"17","Position":"67044554-67056797","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"55","RNA tissue specific nTPM":{"skeletal muscle":"327.7","tongue":"121.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"323","RNA single cell type specific nTPM":{"Skeletal myocytes":"141.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"1.6","head and neck cancer":"1.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"basal ganglia":"3.4"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"}},{"Gene":"CACNG2","Gene synonym":["MGC138502","MGC138504","stargazin"],"Ensembl":"ENSG00000166862","Gene description":"Calcium voltage-gated channel auxiliary subunit gamma 2","Uniprot":["Q9Y698"],"Chromosome":"22","Position":"36560857-36703752","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"20.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Excitatory neurons":"86.2","Horizontal cells":"32.7","Inhibitory neurons":"117.0","Oligodendrocyte precursor cells":"41.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"1.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CACNG3","Gene synonym":[],"Ensembl":"ENSG00000006116","Gene description":"Calcium voltage-gated channel auxiliary subunit gamma 3","Uniprot":["O60359"],"Chromosome":"16","Position":"24256335-24362412","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"53.4","retina":"17.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Excitatory neurons":"154.9","Horizontal cells":"59.0","Inhibitory neurons":"104.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"glioma":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"41","RNA cell line specific nTPM":{"Bone cancer":"4.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077238"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA077238":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CACNG4","Gene synonym":["MGC11138","MGC24983"],"Ensembl":"ENSG00000075461","Gene description":"Calcium voltage-gated channel auxiliary subunit gamma 4","Uniprot":["Q9UBN1"],"Chromosome":"17","Position":"66964707-67033398","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"35.1","prostate":"11.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 1":"35.4","Oligodendrocyte precursor cells":"139.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"breast cancer":"30.3","glioma":"35.8","ovarian cancer":"14.8","prostate cancer":"10.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"55.9"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 1","Pancreas - Alpha cells","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"118.1"},"Antibody":["HPA005803","HPA065370"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA005803":"AB_2667439","HPA065370":"AB_2685480"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"}},{"Gene":"CACNG5","Gene synonym":[],"Ensembl":"ENSG00000075429","Gene description":"Calcium voltage-gated channel auxiliary subunit gamma 5","Uniprot":["Q9UF02"],"Chromosome":"17","Position":"66835117-66894751","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"brain":"11.2","retina":"15.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Horizontal cells":"92.9","Oligodendrocyte precursor cells":"71.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"1.1","prostate cancer":"1.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"124.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050115"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050115":"AB_2681022"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CACNG6","Gene synonym":[],"Ensembl":"ENSG00000130433","Gene description":"Calcium voltage-gated channel auxiliary subunit gamma 6","Uniprot":["Q9BXT2"],"Chromosome":"19","Position":"53991637-54012666","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"skeletal muscle":"90.7","tongue":"29.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"8.3","Respiratory ciliated cells":"17.7","Skeletal myocytes":"32.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"2.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"107","RNA blood cell specific nTPM":{"basophil":"13.3","eosinophil":"8.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"133","RNA blood lineage specific nTPM":{"granulocytes":"13.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"10.9","pancreatic cancer":"9.8"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056615"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA056615":"AB_2683192"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CACNG7","Gene synonym":[],"Ensembl":"ENSG00000105605","Gene description":"Calcium voltage-gated channel auxiliary subunit gamma 7","Uniprot":["P62955"],"Chromosome":"19","Position":"53909278-53943950","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"56.6","retina":"17.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"12.0","Bipolar cells":"10.3","Excitatory neurons":"31.5","Horizontal cells":"44.2","Inhibitory neurons":"42.3","Oligodendrocyte precursor cells":"22.1","Oligodendrocytes":"15.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"16","RNA cancer specific FPKM":{"glioma":"29.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bile duct cancer":"17.8","Neuroblastoma":"33.7","Rhabdoid":"30.3","thyroid cancer":"10.3"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CACNG8","Gene synonym":[],"Ensembl":"ENSG00000142408","Gene description":"Calcium voltage-gated channel auxiliary subunit gamma 8","Uniprot":["Q8WXS5"],"Chromosome":"19","Position":"53962937-53990215","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"37","RNA tissue specific nTPM":{"brain":"33.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"61.0","Horizontal cells":"41.0","Inhibitory neurons":"64.3","Oligodendrocyte precursor cells":"28.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"5.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"granulocytes":"5.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"12.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041351"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041351":"AB_10796666"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"}},{"Gene":"CAD","Gene synonym":["GATD4"],"Ensembl":"ENSG00000084774","Gene description":"Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase","Uniprot":["P27708"],"Chromosome":"2","Position":"27217369-27243943","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Pyrimidine biosynthesis"],"Molecular function":["Allosteric enzyme","Hydrolase","Ligase","Multifunctional enzyme","Transferase"],"Disease involvement":["Cancer-related genes","Congenital disorder of glycosylation","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB007781","HPA065158","HPA069341"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB007781":"AB_562057","HPA065158":null,"HPA069341":"AB_2686125"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-11"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.82e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-3"}},{"Gene":"CADM1","Gene synonym":["BL2","IGSF4","IGSF4A","Necl-2","NECL2","RA175","ST17","SYNCAM","SYNCAM1","TSLC1"],"Ensembl":"ENSG00000182985","Gene description":"Cell adhesion molecule 1","Uniprot":["Q9BY67"],"Chromosome":"11","Position":"115169218-115504957","Protein class":["Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cell adhesion","Differentiation","Host-virus interaction","Immunity","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"287.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"950.2","Bipolar cells":"525.1","Muller glia cells":"428.5","Oligodendrocyte precursor cells":"647.9","Oligodendrocytes":"587.9","Rod photoreceptor cells":"766.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"8.0","myeloid DC":"8.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"8.1","T-cells":"8.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Lung - Alveolar cells type 1","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037266"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB037266":"AB_532287"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"}},{"Gene":"CADM2","Gene synonym":["IGSF4D","Necl-3","NECL3","SynCAM2"],"Ensembl":"ENSG00000175161","Gene description":"Cell adhesion molecule 2","Uniprot":["Q8N3J6"],"Chromosome":"3","Position":"84958989-86074429","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"42.1","retina":"94.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"1923.5","Excitatory neurons":"4039.3","Inhibitory neurons":"3546.8","Oligodendrocyte precursor cells":"3460.4","Oligodendrocytes":"4777.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"7.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"6.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"6.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"10.8","Sarcoma":"8.6"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010024"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"250000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 26: NCI-H716 - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010024":"AB_2068039"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"}},{"Gene":"CADM3","Gene synonym":["BIgR","FLJ10698","IGSF4B","Necl-1","NECL1","SynCAM3","TSLL1"],"Ensembl":"ENSG00000162706","Gene description":"Cell adhesion molecule 3","Uniprot":["Q8N126"],"Chromosome":"1","Position":"159171609-159203313","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"151.6","placenta":"80.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"120.3","Excitatory neurons":"35.0","Horizontal cells":"56.4","Inhibitory neurons":"39.5","Melanocytes":"64.4","Muller glia cells":"32.5","Schwann cells":"89.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"27.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"54.1","skin cancer":"22.2"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Colon - Enteric glia cells","Lung - Fibroblast_2","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002981","CAB025746"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"800000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025746":null,"HPA002981":"AB_1078916"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.75e-4"}},{"Gene":"CADM4","Gene synonym":["IGSF4C","Necl-4","SynCAM4","TSLL2"],"Ensembl":"ENSG00000105767","Gene description":"Cell adhesion molecule 4","Uniprot":["Q8NFZ8"],"Chromosome":"19","Position":"43622368-43639850","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"186.0","choroid plexus":"108.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Melanocytes":"34.8","Oligodendrocyte precursor cells":"40.4","Oligodendrocytes":"48.0","Schwann cells":"76.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"108.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"plasmacytoid DC":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"1.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"135.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012612"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8200000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA012612":"AB_1851530"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.28e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"}},{"Gene":"CADPS","Gene synonym":["CAPS","CAPS1","KIAA1121","UNC-31"],"Ensembl":"ENSG00000163618","Gene description":"Calcium dependent secretion activator","Uniprot":["Q9ULU8"],"Chromosome":"3","Position":"62398346-62875416","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Exocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"84.6","retina":"184.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"666.1","Cone photoreceptor cells":"305.0","Excitatory neurons":"817.6","Horizontal cells":"239.7","Inhibitory neurons":"1128.7","Oligodendrocyte precursor cells":"255.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"11.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Lung - Mast cells","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059328"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059328":"AB_2683982"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-3"}},{"Gene":"CALCOCO1","Gene synonym":["calphoglin","Cocoa","KIAA1536"],"Ensembl":"ENSG00000012822","Gene description":"Calcium binding and coiled-coil domain 1","Uniprot":["Q9P1Z2"],"Chromosome":"12","Position":"53708517-53727745","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Activator"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038313","HPA038314"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA038313":"AB_10675794","HPA038314":"AB_10672587"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-3"}},{"Gene":"CALCOCO2","Gene synonym":["MGC17318","NDP52"],"Ensembl":"ENSG00000136436","Gene description":"Calcium binding and coiled-coil domain 2","Uniprot":["Q13137"],"Chromosome":"17","Position":"48831018-48866522","Protein class":["Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"942.7","Late spermatids":"495.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022989","HPA023019","HPA023195"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA022989":"AB_1845914","HPA023019":"AB_1845915","HPA023195":"AB_1845916"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"}},{"Gene":"CALCR","Gene synonym":["CTR"],"Ensembl":"ENSG00000004948","Gene description":"Calcitonin receptor","Uniprot":[],"Chromosome":"7","Position":"93424486-93574730","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.8","kidney":"1.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"16.9","Late spermatids":"9.4","Microglial cells":"15.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"renal cancer":"1.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"2.9","Uterine cancer":"3.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"6.3","hypothalamus":"24.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028962","HPA061428"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cell Junctions","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Vesicles","Centriolar satellite"],"Antibody RRID":{"HPA028962":"AB_10602339","HPA061428":"AB_2732661"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"}},{"Gene":"CALCRL","Gene synonym":["CGRPR","CRLR"],"Ensembl":"ENSG00000064989","Gene description":"Calcitonin receptor like receptor","Uniprot":["Q16602"],"Chromosome":"2","Position":"187341964-187448460","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"70.7","lung":"76.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"133.5","Endometrial stromal cells":"100.1","Endothelial cells":"269.0","Oligodendrocyte precursor cells":"280.6","Schwann cells":"75.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"2.6","myeloid DC":"9.2","plasmacytoid DC":"2.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"9.2","monocytes":"2.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Rhabdoid":"12.3","Sarcoma":"23.8"},"RNA tissue cell type enrichment":["Colon - Endothelial cells","Prostate - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008070","HPA046515"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA008070":"AB_1845912","HPA046515":"AB_2679681"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"}},{"Gene":"CALHM1","Gene synonym":["FAM26C"],"Ensembl":"ENSG00000185933","Gene description":"Calcium homeostasis modulator 1","Uniprot":["Q8IU99"],"Chromosome":"10","Position":"103453240-103458900","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Sensory transduction","Taste","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"1.5","Myeloma":"2.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061816"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA061816":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"}},{"Gene":"CALHM2","Gene synonym":["FAM26B"],"Ensembl":"ENSG00000138172","Gene description":"Calcium homeostasis modulator family member 2","Uniprot":["Q9HA72"],"Chromosome":"10","Position":"103446786-103452402","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"86.5","Fibroblasts":"37.8","Hofbauer cells":"49.1","Leydig cells":"45.8","monocytes":"39.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Heart muscle - Fibroblasts","Lung - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014706"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA014706":"AB_2243916"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-1"}},{"Gene":"CALHM3","Gene synonym":["bA225H22.7","FAM26A"],"Ensembl":"ENSG00000183128","Gene description":"Calcium homeostasis modulator 3","Uniprot":["Q86XJ0"],"Chromosome":"10","Position":"103472804-103479240","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sensory transduction","Taste","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1.5","Extravillous trophoblasts":"8.2","Late spermatids":"2.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"2.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"5.6"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018205"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018205":"AB_2069267"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"}},{"Gene":"CALHM4","Gene synonym":["C6orf78","FAM26D","FLJ32239"],"Ensembl":"ENSG00000164451","Gene description":"Calcium homeostasis modulator family member 4","Uniprot":["Q5JW98"],"Chromosome":"6","Position":"116529013-116558868","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"placenta":"23.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"46","RNA single cell type specific nTPM":{"Cytotrophoblasts":"27.2","Syncytiotrophoblasts":"87.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"1.7"},"RNA tissue cell type enrichment":["Kidney - Podocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048014"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA048014":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-4"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"CALHM5","Gene synonym":["C6orf188","dJ493F7.3","FAM26E","MGC45451"],"Ensembl":"ENSG00000178033","Gene description":"Calcium homeostasis modulator family member 5","Uniprot":["Q8N5C1"],"Chromosome":"6","Position":"116511639-116524788","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"8.5","Endothelial cells":"5.5","Fibroblasts":"6.0","Peritubular cells":"4.1","Schwann cells":"4.2","Sertoli cells":"5.5","Smooth muscle cells":"8.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034969","HPA034970"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA034969":"AB_10670299","HPA034970":"AB_2674390"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-3"}},{"Gene":"CALHM6","Gene synonym":["C6orf187","dJ93H18.5","FAM26F","INAM","OTTHUMP00000017061","OTTHUMP00000017062","RP1-93H18.5"],"Ensembl":"ENSG00000188820","Gene description":"Calcium homeostasis modulator family member 6","Uniprot":["Q5R3K3"],"Chromosome":"6","Position":"116461370-116463771","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"136.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"66.5","Hofbauer cells":"70.7","Kupffer cells":"100.5","Macrophages":"83.0","monocytes":"231.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"724.6","non-classical monocyte":"861.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"16.3"},"RNA tissue cell type enrichment":["Liver - Kupffer cells","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.31e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-3"}},{"Gene":"CALN1","Gene synonym":["CABP8"],"Ensembl":"ENSG00000183166","Gene description":"Calneuron 1","Uniprot":["Q9BXU9"],"Chromosome":"7","Position":"71779491-72447151","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"adrenal gland":"11.3","brain":"44.3","lymphoid tissue":"24.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"86.0","Excitatory neurons":"128.5","Inhibitory neurons":"208.2","Oligodendrocyte precursor cells":"42.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"4.2","Leukemia":"2.3","Myeloma":"7.9","Neuroblastoma":"2.3"},"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036278","HPA036708"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA036278":"AB_10673125","HPA036708":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"}},{"Gene":"CALY","Gene synonym":["CALCYON","DRD1IP","NSG3"],"Ensembl":"ENSG00000130643","Gene description":"Calcyon neuron specific vesicular protein","Uniprot":["Q9NYX4"],"Chromosome":"10","Position":"133324072-133336935","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"236.9","pituitary gland":"167.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"132.9","Excitatory neurons":"71.5","Horizontal cells":"97.4","Inhibitory neurons":"125.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"pancreatic cancer":"7.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"2.3"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042283"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042283":"AB_10794417"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.54e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"}},{"Gene":"CAMK1","Gene synonym":["CaMKI","CaMKI-alpha"],"Ensembl":"ENSG00000134072","Gene description":"Calcium\/calmodulin dependent protein kinase I","Uniprot":["Q14012"],"Chromosome":"3","Position":"9757347-9769992","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Differentiation","Neurogenesis"],"Molecular function":["Allosteric enzyme","Calmodulin-binding","Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"85.5","monocytes":"98.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"eosinophil":"280.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"280.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB031904","HPA051409"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB031904":"AB_630964","HPA051409":"AB_2681473"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.52e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"}},{"Gene":"CAMK1D","Gene synonym":["CKLiK"],"Ensembl":"ENSG00000183049","Gene description":"Calcium\/calmodulin dependent protein kinase ID","Uniprot":["Q8IU85"],"Chromosome":"10","Position":"12349547-12835545","Protein class":["Enzymes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Inflammatory response","Neurogenesis"],"Molecular function":["Allosteric enzyme","Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"57.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"336.0","Excitatory neurons":"411.1","Inhibitory neurons":"228.8","Microglial cells":"164.2","Rod photoreceptor cells":"224.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"amygdala":"14.9","basal ganglia":"16.7","cerebral cortex":"35.6","hippocampal formation":"29.6","white matter":"14.5"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"75.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"75.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007266"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007266":"AB_1078389"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.67e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"}},{"Gene":"CAMK1G","Gene synonym":["CLICKIII","dJ272L16.1","VWS1"],"Ensembl":"ENSG00000008118","Gene description":"Calcium\/calmodulin dependent protein kinase IG","Uniprot":["Q96NX5"],"Chromosome":"1","Position":"209583714-209613939","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Allosteric enzyme","Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"40.5","kidney":"11.1","ovary":"21.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"19.7","Inhibitory neurons":"15.1","Peritubular cells":"6.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"9.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"}},{"Gene":"CAMK2A","Gene synonym":["CAMKA","CaMKII\u00c3\u017d\u00c2\u00b1","CaMKIINalpha","KIAA0968"],"Ensembl":"ENSG00000070808","Gene description":"Calcium\/calmodulin dependent protein kinase II alpha","Uniprot":["Q9UQM7"],"Chromosome":"5","Position":"150219491-150290291","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"662.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"242.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"glioma":"6.0"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"662.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"4.5"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebral cortex":"1071.1"},"Antibody":["CAB004330","HPA051783","HPA051785","HPA053973"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"66000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions","Cytosol"],"Antibody RRID":{"CAB004330":"AB_626788","HPA051783":"AB_2681608","HPA051785":"AB_2681609","HPA053973":"AB_2682328"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"}},{"Gene":"CAMK2B","Gene synonym":["CAM2","CAMK2","CAMKB","CaMKII\u00c3\u017d\u00c2\u00b2"],"Ensembl":"ENSG00000058404","Gene description":"Calcium\/calmodulin dependent protein kinase II beta","Uniprot":["Q13554"],"Chromosome":"7","Position":"44217150-44334577","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Actin-binding","Calmodulin-binding","Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"248.8","skeletal muscle":"132.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"708.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"6.0","thyroid cancer":"6.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"11.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Heart muscle - Cardiomyocytes","Pancreas - Alpha cells","Pancreas - Beta cells","Skin - Sebaceous gland cells","Stomach - Gastric enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006849","HPA026307","HPA051783","HPA051785","HPA053973"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"600000","Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions","Cytosol"],"Antibody RRID":{"CAB006849":null,"HPA026307":"AB_1845941","HPA051783":"AB_2681608","HPA051785":"AB_2681609","HPA053973":"AB_2682328"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"}},{"Gene":"CAMK2D","Gene synonym":["CAMKD"],"Ensembl":"ENSG00000145349","Gene description":"Calcium\/calmodulin dependent protein kinase II delta","Uniprot":["Q13557"],"Chromosome":"4","Position":"113451032-113761927","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"159.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"346.4","Inhibitory neurons":"195.9","Oligodendrocyte precursor cells":"194.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026281","HPA051783","HPA051785","HPA053973"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions","Cytosol"],"Antibody RRID":{"HPA026281":"AB_1845944","HPA051783":"AB_2681608","HPA051785":"AB_2681609","HPA053973":"AB_2682328"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"}},{"Gene":"CAMK2G","Gene synonym":["CAMKG"],"Ensembl":"ENSG00000148660","Gene description":"Calcium\/calmodulin dependent protein kinase II gamma","Uniprot":["Q13555"],"Chromosome":"10","Position":"73812501-73874591","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Calmodulin-binding","Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"154.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"397.9","Cytotrophoblasts":"175.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"133.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Prostate - Smooth muscle cells","Skeletal muscle - Skeletal myocytes","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040656","HPA051783","HPA051785","HPA053973"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions","Cytosol"],"Antibody RRID":{"HPA040656":"AB_2677065","HPA051783":"AB_2681608","HPA051785":"AB_2681609","HPA053973":"AB_2682328"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"}},{"Gene":"CAMK4","Gene synonym":["CaMK-GR","CaMKIV"],"Ensembl":"ENSG00000152495","Gene description":"Calcium\/calmodulin dependent protein kinase IV","Uniprot":["Q16566"],"Chromosome":"5","Position":"111223653-111494886","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity","Inflammatory response"],"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"70.4","lymphoid tissue":"55.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"361.0","Excitatory neurons":"209.0","Inhibitory neurons":"128.6","Late spermatids":"118.4","Oligodendrocyte precursor cells":"127.6","T-cells":"88.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"basal ganglia":"30.6","cerebellum":"70.4"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"MAIT T-cell":"24.3","memory CD4 T-cell":"17.3","memory CD8 T-cell":"13.5","naive CD4 T-cell":"33.1","naive CD8 T-cell":"18.5","T-reg":"21.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"T-cells":"33.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"27.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Liver - Hepatic stellate cells","Skin - T-cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004347","HPA011753","HPA017206"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"CAB004347":"AB_626793","HPA011753":"AB_1845950","HPA017206":"AB_1845949"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-3"}},{"Gene":"CAMKK1","Gene synonym":["CAMKKA","DKFZp761M0423","MGC34095"],"Ensembl":"ENSG00000004660","Gene description":"Calcium\/calmodulin dependent protein kinase kinase 1","Uniprot":["Q8N5S9"],"Chromosome":"17","Position":"3860315-3894891","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"54.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"40.1","Excitatory neurons":"51.9","Rod photoreceptor cells":"27.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"amygdala":"21.5","basal ganglia":"24.2","cerebral cortex":"54.4","hippocampal formation":"24.8","white matter":"31.9"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Liver - Vascular Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009111","HPA028062"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009111":"AB_2068406","HPA028062":"AB_1845954"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.65e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"}},{"Gene":"CAMKK2","Gene synonym":["CAMKK","CAMKKB","KIAA0787","MGC15254"],"Ensembl":"ENSG00000110931","Gene description":"Calcium\/calmodulin dependent protein kinase kinase 2","Uniprot":["Q96RR4"],"Chromosome":"12","Position":"121237675-121298308","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"135.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"63.9","Late spermatids":"90.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"prostate cancer":"56.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"32.7","eosinophil":"62.1","intermediate monocyte":"42.3","myeloid DC":"15.9","neutrophil":"39.2","non-classical monocyte":"39.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"15.9","granulocytes":"62.1","monocytes":"42.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017389","HPA063713"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017389":"AB_1845956","HPA063713":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"}},{"Gene":"CAMKV","Gene synonym":["MGC8407","VACAMKL"],"Ensembl":"ENSG00000164076","Gene description":"CaM kinase like vesicle associated","Uniprot":["Q8NCB2"],"Chromosome":"3","Position":"49857988-49869935","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"91.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"32.2","Horizontal cells":"42.3","Inhibitory neurons":"26.3","Late spermatids":"9.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"4.0","testis cancer":"5.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"23.4"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007656","CAB034931"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"CAB034931":"AB_2068550","HPA007656":"AB_1078391"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"}},{"Gene":"CAMLG","Gene synonym":["CAML","GET2"],"Ensembl":"ENSG00000164615","Gene description":"Calcium modulating ligand","Uniprot":["P49069"],"Chromosome":"5","Position":"134738495-134752157","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["ER-Golgi transport","Host-virus interaction","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"708.5","Late spermatids":"1755.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052636","HPA056472"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Nucleoli"],"Antibody RRID":{"HPA052636":"AB_2681893","HPA056472":"AB_2683143"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"}},{"Gene":"CAMSAP3","Gene synonym":["KIAA1543","Nezha","PPP1R80"],"Ensembl":"ENSG00000076826","Gene description":"Calmodulin regulated spectrin associated protein family member 3","Uniprot":["Q9P1Y5"],"Chromosome":"19","Position":"7595863-7618304","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"62.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"40.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Colon - Colon enterocytes","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043830"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043830":"AB_10795879"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.55e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"}},{"Gene":"CAMTA1","Gene synonym":["KIAA0833"],"Ensembl":"ENSG00000171735","Gene description":"Calmodulin binding transcription activator 1","Uniprot":["Q9Y6Y1"],"Chromosome":"1","Position":"6785454-7769706","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"795.2","Proximal tubular cells":"676.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036342","HPA036343"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036342":"AB_2675072","HPA036343":"AB_10671839"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.10e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-3"}},{"Gene":"CAMTA2","Gene synonym":["KIAA0909"],"Ensembl":"ENSG00000108509","Gene description":"Calmodulin binding transcription activator 2","Uniprot":["O94983"],"Chromosome":"17","Position":"4967992-4987675","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"53.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027835","HPA051147"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Actin filaments","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Actin filaments","Mitochondria","Cytosol"],"Antibody RRID":{"HPA027835":null,"HPA051147":"AB_2681362"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.00e-8"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"}},{"Gene":"CANT1","Gene synonym":["SCAN-1","SHAPY"],"Ensembl":"ENSG00000171302","Gene description":"Calcium activated nucleotidase 1","Uniprot":["Q8WVQ1"],"Chromosome":"17","Position":"78991716-79009867","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"127.6","Intestinal goblet cells":"152.6","Prostatic glandular cells":"103.6","Syncytiotrophoblasts":"104.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019627","HPA019639","HPA022818"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA019627":"AB_1845969","HPA019639":"AB_1845970","HPA022818":"AB_1845971"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.41e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"}},{"Gene":"CANX","Gene synonym":["CNX","IP90","P90"],"Ensembl":"ENSG00000127022","Gene description":"Calnexin","Uniprot":["P27824"],"Chromosome":"5","Position":"179678628-179731641","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Chaperone"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"854.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004738","HPA009433","HPA009696"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB004738":"AB_626784","HPA009433":"AB_1078380","HPA009696":"AB_1078379"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.38e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.17e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"}},{"Gene":"CAPN12","Gene synonym":[],"Ensembl":"ENSG00000182472","Gene description":"Calpain 12","Uniprot":["Q6ZSI9"],"Chromosome":"19","Position":"38730187-38769904","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"gallbladder":"22.8","liver":"24.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"42.3","NK-cells":"28.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"59.3","NK-cell":"25.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"59.3","NK-cells":"25.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"3.0"},"Antibody":["HPA053322"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA053322":"AB_2682111"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.90e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"}},{"Gene":"CAPN5","Gene synonym":["ADNIV","HTRA3","nCL-3","VRNI"],"Ensembl":"ENSG00000149260","Gene description":"Calpain 5","Uniprot":["O15484"],"Chromosome":"11","Position":"77066961-77126155","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"60.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"126.1","Gastric mucus-secreting cells":"72.7","Intestinal goblet cells":"103.5","Paneth cells":"69.4","Proximal enterocytes":"66.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"1.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Heart muscle - Fibroblasts","Liver - Hepatocytes","Skeletal muscle - Fibroblasts","Skin - Fibroblast_1","Stomach - Gastric mucous cells","Testis - Sertoli cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033237","HPA072319"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB033237":"AB_2069673","HPA072319":"AB_2686512"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.16e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"}},{"Gene":"CAPN7","Gene synonym":["PalBH"],"Ensembl":"ENSG00000131375","Gene description":"Calpain 7","Uniprot":["Q9Y6W3"],"Chromosome":"3","Position":"15206152-15252916","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004745","HPA046617"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA004745":null,"HPA046617":"AB_2679721"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.85e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"}},{"Gene":"CAPZA2","Gene synonym":["CAPPA2","CAPZ"],"Ensembl":"ENSG00000198898","Gene description":"Capping actin protein of muscle Z-line subunit alpha 2","Uniprot":["P47755"],"Chromosome":"7","Position":"116811070-116922049","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin capping","Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"565.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007470","HPA007643"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4500000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 69: BICR 18 - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007470":"AB_1845985","HPA007643":"AB_2667886"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.34e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.65e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"}},{"Gene":"CARD19","Gene synonym":["bA370F5.1","BinCARD","C9orf89","MGC11115"],"Ensembl":"ENSG00000165233","Gene description":"Caspase recruitment domain family member 19","Uniprot":["Q96LW7"],"Chromosome":"9","Position":"93096217-93113283","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"204.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010921","HPA010990","HPA038297"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA010921":"AB_10670295","HPA010990":"AB_2668400","HPA038297":"AB_2675938"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.47e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"}},{"Gene":"CASD1","Gene synonym":["C7orf12","FLJ21213","FLJ21879"],"Ensembl":"ENSG00000127995","Gene description":"CAS1 domain containing 1","Uniprot":["Q96PB1"],"Chromosome":"7","Position":"94509219-94557019","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"92.3","Inhibitory neurons":"105.9","Oligodendrocyte precursor cells":"117.4","Oligodendrocytes":"160.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044404","HPA052908"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA044404":"AB_10964353","HPA052908":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"}},{"Gene":"CASK","Gene synonym":["CAGH39","FGS4","LIN2","TNRC8"],"Ensembl":"ENSG00000147044","Gene description":"Calcium\/calmodulin dependent serine protein kinase","Uniprot":["O14936"],"Chromosome":"X","Position":"41514934-41923554","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"132.5","Oligodendrocyte precursor cells":"428.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"47.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"47.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001949","HPA023857"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB001949":null,"HPA023857":"AB_1846035"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.11e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"}},{"Gene":"CASP8","Gene synonym":["Casp-8","FLICE","MACH","MCH5"],"Ensembl":"ENSG00000064012","Gene description":"Caspase 8","Uniprot":["Q14790"],"Chromosome":"2","Position":"201233443-201287711","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"66.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"164.3","T-cells":"91.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001302","CAB002047","HPA005688","HPA006191"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB002047":"AB_563465","HPA001302":"AB_1846057","HPA005688":"AB_1846056","HPA006191":"AB_2667535"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.27e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"}},{"Gene":"CASR","Gene synonym":["FHH","GPRC2A","HHC","HHC1","NSHPT"],"Ensembl":"ENSG00000036828","Gene description":"Calcium sensing receptor","Uniprot":["P41180"],"Chromosome":"3","Position":"122183668-122291629","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"parathyroid gland":"654.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"48.1","Enteroendocrine cells":"12.0","Granulosa cells":"20.7","Pancreatic endocrine cells":"17.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"pancreatic cancer":"5.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"thyroid cancer":"6.8"},"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Stomach - Gastric enteroendocrine cells","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039686","HPA050335"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039686":"AB_10673536","HPA050335":"AB_2681092"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"}},{"Gene":"CATSPER1","Gene synonym":["CATSPER"],"Ensembl":"ENSG00000175294","Gene description":"Cation channel sperm associated 1","Uniprot":["Q8NEC5"],"Chromosome":"11","Position":"66016752-66026479","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Differentiation","Ion transport","Spermatogenesis","Transport"],"Molecular function":["Calcium channel","Developmental protein","Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"34","RNA tissue specific nTPM":{"testis":"17.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"53.8","granulocytes":"50.8","Hofbauer cells":"39.2","Kupffer cells":"21.1","Langerhans cells":"13.8","Macrophages":"15.0","NK-cells":"27.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"16.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"}},{"Gene":"CATSPER2","Gene synonym":[],"Ensembl":"ENSG00000166762","Gene description":"Cation channel sperm associated 2","Uniprot":["Q96P56"],"Chromosome":"15","Position":"43628503-43668118","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Differentiation","Ion transport","Spermatogenesis","Transport"],"Molecular function":["Calcium channel","Developmental protein","Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.6","retina":"22.8","testis":"15.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"82.7","Early spermatids":"71.8","Horizontal cells":"41.7","Rod photoreceptor cells":"174.7","Spermatocytes":"65.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"14.6"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-5"}},{"Gene":"CATSPER3","Gene synonym":["CACRC"],"Ensembl":"ENSG00000152705","Gene description":"Cation channel sperm associated 3","Uniprot":["Q86XQ3"],"Chromosome":"5","Position":"134967907-135011696","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Differentiation","Ion transport","Spermatogenesis","Transport"],"Molecular function":["Calcium channel","Developmental protein","Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"testis":"29.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"239.6","Late spermatids":"64.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-3"}},{"Gene":"CATSPER4","Gene synonym":[],"Ensembl":"ENSG00000188782","Gene description":"Cation channel sperm associated 4","Uniprot":["Q7RTX7"],"Chromosome":"1","Position":"26190561-26202968","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Differentiation","Ion transport","Spermatogenesis","Transport"],"Molecular function":["Calcium channel","Developmental protein","Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"53","RNA tissue specific nTPM":{"testis":"11.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"82.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045257"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045257":"AB_10968995"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-5"}},{"Gene":"CATSPERB","Gene synonym":["C14orf161","FLJ14298"],"Ensembl":"ENSG00000133962","Gene description":"Cation channel sperm associated auxiliary subunit beta","Uniprot":["Q9H7T0"],"Chromosome":"14","Position":"91580696-91780707","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"pancreas":"10.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"29.2","Exocrine glandular cells":"14.8","Gastric mucus-secreting cells":"7.2","Glandular and luminal cells":"6.1","Mucus glandular cells":"6.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035134"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035134":"AB_10671510"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"}},{"Gene":"CATSPERD","Gene synonym":["MGC39581","TMEM146"],"Ensembl":"ENSG00000174898","Gene description":"Cation channel sperm associated auxiliary subunit delta","Uniprot":["Q86XM0"],"Chromosome":"19","Position":"5720637-5778734","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"testis":"8.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"76.8","Endometrial ciliated cells":"75.3","Late spermatids":"180.4","Respiratory ciliated cells":"91.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024056"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024056":"AB_1858093"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"}},{"Gene":"CATSPERE","Gene synonym":["C1orf101","MGC33370"],"Ensembl":"ENSG00000179397","Gene description":"Catsper channel auxiliary subunit epsilon","Uniprot":["Q5SY80"],"Chromosome":"1","Position":"244454377-244641177","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"testis":"21.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"22.1","Early spermatids":"42.1","Excitatory neurons":"18.4","Inhibitory neurons":"17.0","Oligodendrocyte precursor cells":"19.7","Oligodendrocytes":"40.2","Spermatocytes":"31.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"}},{"Gene":"CATSPERG","Gene synonym":["C19orf15","DKFZp434A1022","FLJ46353"],"Ensembl":"ENSG00000099338","Gene description":"Cation channel sperm associated auxiliary subunit gamma","Uniprot":["Q6ZRH7"],"Chromosome":"19","Position":"38335775-38370943","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"testis":"31.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"24.5","Gastric mucus-secreting cells":"22.7","Late spermatids":"47.9","Proximal enterocytes":"18.6","Spermatocytes":"25.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052777"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA052777":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"}},{"Gene":"CAV1","Gene synonym":["CAV"],"Ensembl":"ENSG00000105974","Gene description":"Caveolin 1","Uniprot":["Q03135"],"Chromosome":"7","Position":"116524994-116561179","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Congenital generalized lipodystrophy","Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"2061.1","Alveolar cells type 1":"1354.7","Basal keratinocytes":"839.9","Endothelial cells":"1053.2","Smooth muscle cells":"716.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"basophil":"14.6","memory B-cell":"5.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"57","RNA blood lineage specific nTPM":{"B-cells":"5.1","granulocytes":"14.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Kidney - Fibroblasts","Liver - Hepatic stellate cells","Lung - Alveolar cells type 1","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"122.1"},"Antibody":["CAB003791","HPA049326"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB003791":"AB_562068","HPA049326":"AB_2680714"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.17e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-3"}},{"Gene":"CAV2","Gene synonym":["CAV"],"Ensembl":"ENSG00000105971","Gene description":"Caveolin 2","Uniprot":["P51636"],"Chromosome":"7","Position":"116287380-116508541","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"227.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"290.5","Alveolar cells type 1":"679.6","Basal keratinocytes":"322.5","Basal respiratory cells":"317.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"114","RNA blood cell specific nTPM":{"basophil":"97.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"399","RNA blood lineage specific nTPM":{"granulocytes":"97.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013488","HPA044810"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB013488":"AB_2533493","HPA044810":"AB_2679098"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.80e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.21e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"}},{"Gene":"CAV3","Gene synonym":["LGMD1C","LQT9","VIP-21","VIP21"],"Ensembl":"ENSG00000182533","Gene description":"Caveolin 3","Uniprot":["P56539"],"Chromosome":"3","Position":"8733802-8841808","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant","Limb-girdle muscular dystrophy","Long QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"182.7","tongue":"72.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Cardiomyocytes":"15.9","Skeletal myocytes":"58.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"0.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"57","RNA cell line specific nTPM":{"Sarcoma":"16.9"},"RNA tissue cell type enrichment":["Adipose visceral - Smooth muscle cells","Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Testis - Late spermatids","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017518","CAB018557","HPA054488","HPA072988"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB017518":"AB_628860","CAB018557":"AB_626814","HPA054488":"AB_2682504","HPA072988":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CAVIN3","Gene synonym":["cavin-3","HSRBC","MGC20400","PRKCDBP","SRBC"],"Ensembl":"ENSG00000170955","Gene description":"Caveolae associated protein 3","Uniprot":["Q969G5"],"Chromosome":"11","Position":"6318946-6320532","Protein class":["Predicted intracellular proteins"],"Biological process":["Biological rhythms"],"Molecular function":null,"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Melanocytes":"306.5","Sertoli cells":"196.3","Smooth muscle cells":"277.6","Spermatocytes":"314.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"16.2","myeloid DC":"42.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"42.8","monocytes":"16.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"134.4"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055136","HPA073327"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA055136":"AB_2682711","HPA073327":"AB_2686595"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.75e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"}},{"Gene":"CBARP","Gene synonym":["BARP","C19orf26","DOS","MGC40084"],"Ensembl":"ENSG00000099625","Gene description":"CACN subunit beta associated regulatory protein","Uniprot":["Q8N350"],"Chromosome":"19","Position":"1228287-1238027","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"15.3","pituitary gland":"22.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"19.4","Early spermatids":"57.3","Horizontal cells":"16.7","Late spermatids":"87.9","Spermatocytes":"40.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012777"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA012777":"AB_2067005"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-5"}},{"Gene":"CBFA2T3","Gene synonym":["ETO2","MTG16","MTGR2","RUNX1T3","ZMYND4"],"Ensembl":"ENSG00000129993","Gene description":"CBFA2\/RUNX1 partner transcriptional co-repressor 3","Uniprot":["O75081"],"Chromosome":"16","Position":"88874858-88977207","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Repressor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.8","lymphoid tissue":"29.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"23.3","B-cells":"31.8","dendritic cells":"61.4","Langerhans cells":"23.4","monocytes":"29.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"35.8"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"10.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"51.2","lymphoma":"32.6"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Liver - Hepatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059931","HPA062423","HPA065890"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA059931":"AB_2684168","HPA062423":"AB_2684758","HPA065890":"AB_2685575"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.95e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-3"}},{"Gene":"CCBE1","Gene synonym":["FLJ30681","KIAA1983"],"Ensembl":"ENSG00000183287","Gene description":"Collagen and calcium binding EGF domains 1","Uniprot":["Q6UXH8"],"Chromosome":"18","Position":"59430939-59697662","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Angiogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"33.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"55.6","Fibroblasts":"20.6","Rod photoreceptor cells":"44.2","Sertoli cells":"19.3","Theca cells":"56.2","Thymic epithelial cells":"25.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"9.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"granulocytes":"9.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"38.4"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Liver - Hepatic stellate cells","Lung - Fibroblast_1","Pancreas - Fibroblasts","Prostate - Smooth muscle cells","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebral cortex":"2.7","hippocampal formation":"8.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041361","HPA041374"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041361":"AB_10796667","HPA041374":"AB_10794515"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"}},{"Gene":"CCDC107","Gene synonym":["MGC31967"],"Ensembl":"ENSG00000159884","Gene description":"Coiled-coil domain containing 107","Uniprot":["Q8WV48"],"Chromosome":"9","Position":"35658290-35661511","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016857","HPA050442"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA016857":"AB_10669751","HPA050442":"AB_2681128"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"}},{"Gene":"CCDC127","Gene synonym":["FLJ25701"],"Ensembl":"ENSG00000164366","Gene description":"Coiled-coil domain containing 127","Uniprot":["Q96BQ5"],"Chromosome":"5","Position":"196868-218153","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045052"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA045052":"AB_10960630"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.01e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.04e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.95e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"}},{"Gene":"CCDC136","Gene synonym":["DKFZP434G156","KIAA1793","NAG6"],"Ensembl":"ENSG00000128596","Gene description":"Coiled-coil domain containing 136","Uniprot":["Q96JN2"],"Chromosome":"7","Position":"128790757-128822132","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Fertilization","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"87.6","retina":"52.5","testis":"185.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"724.5","Late spermatids":"1987.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"26.1"},"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010646","HPA071015"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Nuclear membrane","Plasma membrane"],"Antibody RRID":{"HPA010646":null,"HPA071015":"AB_2686334"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"}},{"Gene":"CCDC141","Gene synonym":["CAMDI","FLJ39502"],"Ensembl":"ENSG00000163492","Gene description":"Coiled-coil domain containing 141","Uniprot":["Q6ZP82"],"Chromosome":"2","Position":"178829757-179050086","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"74.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"43.7","Cardiomyocytes":"163.5","Cholangiocytes":"23.1","Early spermatids":"25.3","granulocytes":"26.9","Late spermatids":"25.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"15.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"8.1","T-cells":"15.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"2.8","Sarcoma":"2.4"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 2","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012718"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA012718":"AB_2072055"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"}},{"Gene":"CCDC142","Gene synonym":["FLJ14397"],"Ensembl":"ENSG00000135637","Gene description":"Coiled-coil domain containing 142","Uniprot":["Q17RM4"],"Chromosome":"2","Position":"74471986-74483408","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"20.8","Rod photoreceptor cells":"21.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056946"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056946":"AB_2683282"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.87e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.46e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.71e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"}},{"Gene":"CCDC157","Gene synonym":[],"Ensembl":"ENSG00000187860","Gene description":"Coiled-coil domain containing 157","Uniprot":["Q569K6"],"Chromosome":"22","Position":"30356635-30378658","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"27.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"109.3","Late spermatids":"144.9","Respiratory ciliated cells":"38.5","Spermatocytes":"50.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042943"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042943":"AB_10794767"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"}},{"Gene":"CCDC163","Gene synonym":["C1orf231","CCDC163P","LOC126661"],"Ensembl":"ENSG00000280670","Gene description":"Coiled-coil domain containing 163","Uniprot":["A0A0D9SF12"],"Chromosome":"1","Position":"45493866-45500079","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"8.5","Plasma cells":"8.2","Spermatocytes":"6.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.05e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"}},{"Gene":"CCDC167","Gene synonym":["C6orf129","dJ153P14.2"],"Ensembl":"ENSG00000198937","Gene description":"Coiled-coil domain containing 167","Uniprot":["Q9P0B6"],"Chromosome":"6","Position":"37482938-37499893","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"277.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"145.2","granulocytes":"140.2","T-cells":"423.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045215"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA045215":"AB_10962866"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.59e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.94e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.71e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"}},{"Gene":"CCDC168","Gene synonym":["C13orf40","FLJ40176"],"Ensembl":"ENSG00000175820","Gene description":"Coiled-coil domain containing 168","Uniprot":["Q8NDH2"],"Chromosome":"13","Position":"102729367-102759072","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"testis":"8.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"1042.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048184","HPA058793","HPA078547"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoli","Centrosome"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA048184":"AB_2680303","HPA058793":"AB_2683823","HPA078547":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"}},{"Gene":"CCDC188","Gene synonym":[],"Ensembl":"ENSG00000234409","Gene description":"Coiled-coil domain containing 188","Uniprot":["H7C350"],"Chromosome":"22","Position":"20148416-20151055","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"testis":"40.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"1004.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"plasmacytoid DC":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"dendritic cells":"1.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"8.1"},"RNA tissue cell type enrichment":["Prostate - Endothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049901"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA049901":"AB_2680943"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"}},{"Gene":"CCDC47","Gene synonym":["GK001"],"Ensembl":"ENSG00000108588","Gene description":"Coiled-coil domain containing 47","Uniprot":["Q96A33"],"Chromosome":"17","Position":"63745255-63776351","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029674","HPA072573","HPA075958"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA029674":"AB_10602703","HPA072573":"AB_2686535","HPA075958":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"}},{"Gene":"CCDC51","Gene synonym":["FLJ12436"],"Ensembl":"ENSG00000164051","Gene description":"Coiled-coil domain containing 51","Uniprot":["Q96ER9"],"Chromosome":"3","Position":"48432164-48440456","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"46.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010980","HPA011408"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA010980":"AB_1846155","HPA011408":"AB_2072212"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"}},{"Gene":"CCDC57","Gene synonym":["FLJ00130","FLJ23754"],"Ensembl":"ENSG00000176155","Gene description":"Coiled-coil domain containing 57","Uniprot":["Q2TAC2"],"Chromosome":"17","Position":"82101460-82212830","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Late spermatids":"720.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"naive CD4 T-cell":"3.7","naive CD8 T-cell":"7.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"7.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023315","HPA023326","HPA023342","HPA023344"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Microtubules"],"Subcellular additional location":["Centriolar satellite","Cytosol"],"Antibody RRID":{"HPA023315":"AB_1846159","HPA023326":"AB_1846160","HPA023342":"AB_2275460","HPA023344":"AB_1846162"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.55e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.28e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-3"}},{"Gene":"CCDC90B","Gene synonym":["MDS011","MDS025"],"Ensembl":"ENSG00000137500","Gene description":"Coiled-coil domain containing 90B","Uniprot":["Q9GZT6"],"Chromosome":"11","Position":"83259097-83286407","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"388.3","Late spermatids":"296.4","Spermatocytes":"317.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011130","HPA011931"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA011130":"AB_1846170","HPA011931":"AB_2072332"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"}},{"Gene":"CCKAR","Gene synonym":[],"Ensembl":"ENSG00000163394","Gene description":"Cholecystokinin A receptor","Uniprot":["P32238"],"Chromosome":"4","Position":"26481396-26490484","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.9","gallbladder":"29.2","stomach 1":"16.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"1.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"0.5"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"hypothalamus":"5.1","midbrain":"6.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"4.5","Neuroblastoma":"9.9"},"RNA tissue cell type enrichment":["Stomach - Chief cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"7.2"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"12.6"},"Antibody":["HPA073900"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA073900":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CCKBR","Gene synonym":[],"Ensembl":"ENSG00000110148","Gene description":"Cholecystokinin B receptor","Uniprot":["P32239"],"Chromosome":"11","Position":"6259806-6272127","Protein class":["Cancer-related genes","FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"brain":"14.1","pancreas":"27.1","stomach 1":"42.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"14.4","Gastric mucus-secreting cells":"15.5","Granulosa cells":"25.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"testis cancer":"9.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"testis cancer":"10.5"},"RNA tissue cell type enrichment":["Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079548"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA079548":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"CCL5","Gene synonym":["D17S136E","MGC17164","RANTES","SCYA5","SISd","TCP228"],"Ensembl":"ENSG00000271503","Gene description":"C-C motif chemokine ligand 5","Uniprot":["P13501"],"Chromosome":"17","Position":"35871491-35880793","Protein class":["Cancer-related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Chemotaxis","Inflammatory response"],"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"122.1","lymphoid tissue":"135.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"NK-cells":"2748.9","T-cells":"2015.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"6788.6","memory CD8 T-cell":"7164.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"NK-cells":"2041.1","T-cells":"7164.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"head and neck cancer":"18.5","Leukemia":"60.2","lymphoma":"48.9","Myeloma":"36.5","thyroid cancer":"41.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB078447"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":20100000,"Blood concentration - Conc. blood MS [pg\/L]":"2900000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB078447":"AB_223462"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.34e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.42e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.61e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"}},{"Gene":"CCL7","Gene synonym":["FIC","MARC","MCP-3","MCP3","NC28","SCYA6","SCYA7"],"Ensembl":"ENSG00000108688","Gene description":"C-C motif chemokine ligand 7","Uniprot":["P80098"],"Chromosome":"17","Position":"34270221-34272242","Protein class":["Cancer-related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Chemotaxis","Inflammatory response"],"Molecular function":["Cytokine","Heparin-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"bone marrow":"25.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hofbauer cells":"50.8","Macrophages":"13.5","Thymic epithelial cells":"26.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"thalamus":"2.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":29700,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"}},{"Gene":"CCM2","Gene synonym":["C7orf22","MGC4607","OSM"],"Ensembl":"ENSG00000136280","Gene description":"CCM2 scaffold protein","Uniprot":["Q9BSQ5"],"Chromosome":"7","Position":"44999475-45076469","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020273","HPA021669","HPA065815"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA020273":"AB_1846185","HPA021669":"AB_1846186","HPA065815":"AB_2685562"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.79e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.45e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.16e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.06e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"}},{"Gene":"CCNC","Gene synonym":["CycC"],"Ensembl":"ENSG00000112237","Gene description":"Cyclin C","Uniprot":["P24863"],"Chromosome":"6","Position":"99542387-99568825","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Cyclin","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010499","HPA069322"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB010499":"AB_2244021","HPA069322":"AB_2686120"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.12e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"}},{"Gene":"CCND2","Gene synonym":[],"Ensembl":"ENSG00000118971","Gene description":"Cyclin D2","Uniprot":["P30279"],"Chromosome":"12","Position":"4269771-4305353","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division"],"Molecular function":["Cyclin"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"398.9","Granulosa cells":"412.4","Langerhans cells":"319.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"83.5","testis cancer":"89.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049138","HPA054196"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA049138":"AB_2680650","HPA054196":"AB_2682412"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.52e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.76e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"}},{"Gene":"CCNI2","Gene synonym":["FLJ16793"],"Ensembl":"ENSG00000205089","Gene description":"Cyclin I family member 2","Uniprot":["Q6ZMN8"],"Chromosome":"5","Position":"132747426-132754403","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Cyclin"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.3","intestine":"3.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"15.5","Gastric mucus-secreting cells":"8.3","Muller glia cells":"4.5","Plasma cells":"4.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"5.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"6.0","lymphoma":"5.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056288"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 34: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA056288":"AB_2683086"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.21e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-7"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"}},{"Gene":"CCNJL","Gene synonym":["FLJ14166"],"Ensembl":"ENSG00000135083","Gene description":"Cyclin J like","Uniprot":["Q8IV13"],"Chromosome":"5","Position":"160249083-160345396","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Cyclin"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"16.5","Alveolar cells type 2":"33.3","Intestinal goblet cells":"29.8","Paneth cells":"32.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"18.6"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"17","RNA blood cell specific nTPM":{"neutrophil":"12.7","NK-cell":"4.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"85","RNA blood lineage specific nTPM":{"granulocytes":"12.7","NK-cells":"4.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Stomach - Parietal cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049970"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049970":"AB_2680974"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.31e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.10e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.02e-4"}},{"Gene":"CCPG1","Gene synonym":["CPR8","KIAA1254"],"Ensembl":"ENSG00000260916","Gene description":"Cell cycle progression 1","Uniprot":["Q9ULG6"],"Chromosome":"15","Position":"55340032-55408510","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"98.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"279.2","neutrophil":"296.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"296.6","monocytes":"84.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009432","HPA026861"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA009432":"AB_2668242","HPA026861":"AB_1846192"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.02e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"}},{"Gene":"CCR1","Gene synonym":["CD191","CKR-1","CMKBR1","MIP1aR","SCYAR1"],"Ensembl":"ENSG00000163823","Gene description":"C-C motif chemokine receptor 1","Uniprot":["P32246"],"Chromosome":"3","Position":"46201711-46208313","Protein class":["CD markers","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"42.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"96.4","Hofbauer cells":"121.6","Kupffer cells":"121.1","Macrophages":"92.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Myeloma":"56.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Liver - Kupffer cells","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"}},{"Gene":"CCR10","Gene synonym":["GPR2"],"Ensembl":"ENSG00000184451","Gene description":"C-C motif chemokine receptor 10","Uniprot":["P46092"],"Chromosome":"17","Position":"42678889-42683917","Protein class":["Cancer-related genes","G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"20.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Plasma cells":"76.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"plasmacytoid DC":"24.7","T-reg":"72.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"24.7","T-cells":"72.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Myeloma":"43.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011684","HPA048007","HPA069188"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB011684":"AB_731502","HPA048007":"AB_2680232","HPA069188":"AB_2686100"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"}},{"Gene":"CCR2","Gene synonym":["CC-CKR-2","CD192","CKR2","CMKBR2","FLJ78302","MCP-1-R"],"Ensembl":"ENSG00000121807","Gene description":"C-C motif chemokine receptor 2","Uniprot":["P41597"],"Chromosome":"3","Position":"46353744-46360940","Protein class":["CD markers","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":["Host-virus interaction","Inflammatory response"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"25.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"61.4","Kupffer cells":"82.3","Langerhans cells":"16.6","Macrophages":"24.2","monocytes":"15.3","Plasma cells":"35.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"560.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Myeloma":"34.2"},"RNA tissue cell type enrichment":["Breast - Plasma cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"2.4"},"Antibody":["CAB003793","HPA063255"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli fibrillar center","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"CAB003793":"AB_344889","HPA063255":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.87e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"}},{"Gene":"CCR3","Gene synonym":["CC-CKR-3","CD193","CKR3","CMKBR3"],"Ensembl":"ENSG00000183625","Gene description":"C-C motif chemokine receptor 3","Uniprot":["P51677"],"Chromosome":"3","Position":"46163604-46266706","Protein class":["CD markers","G-protein coupled receptors","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"2.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"25","RNA blood cell specific nTPM":{"basophil":"3389.4","eosinophil":"2509.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"109","RNA blood lineage specific nTPM":{"granulocytes":"3389.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"3.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003795","HPA069514"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB003795":"AB_562259","HPA069514":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"}},{"Gene":"CCR4","Gene synonym":["CC-CKR-4","CD194","ChemR13","CKR4","CMKBR4","k5-5"],"Ensembl":"ENSG00000183813","Gene description":"C-C motif chemokine receptor 4","Uniprot":["P51679"],"Chromosome":"3","Position":"32951644-32956349","Protein class":["CD markers","FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"13.0","urinary bladder":"5.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"T-cells":"11.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"T-reg":"60.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"41","RNA blood lineage specific nTPM":{"T-cells":"60.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"24.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Breast - T-cells","Skin - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031613"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA031613":"AB_10601096"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"}},{"Gene":"CCR5","Gene synonym":["CC-CKR-5","CD195","CKR-5","CKR5","CMKBR5","IDDM22"],"Ensembl":"ENSG00000160791","Gene description":"C-C motif chemokine receptor 5","Uniprot":["P51681"],"Chromosome":"3","Position":"46370854-46376206","Protein class":["CD markers","Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["G-protein coupled receptor","Host cell receptor for virus entry","Receptor","Transducer"],"Disease involvement":["Diabetes mellitus","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"15.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"10.3","Langerhans cells":"41.3","Macrophages":"11.6","T-cells":"12.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"39.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"1.5","Myeloma":"1.4"},"RNA tissue cell type enrichment":["Lung - T-cells","Prostate - T-cells","Skin - T-cells","Stomach - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.42e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.33e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"}},{"Gene":"CCR6","Gene synonym":["BN-1","CD196","CKR-L3","CMKBR6","DCR2","DRY-6","GPR-CY4","GPR29","STRL22"],"Ensembl":"ENSG00000112486","Gene description":"C-C motif chemokine receptor 6","Uniprot":["P51684"],"Chromosome":"6","Position":"167111807-167139696","Protein class":["CD markers","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"35.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"B-cells":"15.9","T-cells":"13.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"77.4","T-cells":"74.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"6.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Prostate - T-cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"basal ganglia":"1.8"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006820","HPA014488"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB006820":null,"HPA014488":"AB_1846639"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"}},{"Gene":"CCR7","Gene synonym":["BLR2","CD197","CDw197","CMKBR7","EBI1"],"Ensembl":"ENSG00000126353","Gene description":"C-C motif chemokine receptor 7","Uniprot":["P32248"],"Chromosome":"17","Position":"40553769-40565472","Protein class":["Cancer-related genes","CD markers","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"21.3","lymphoid tissue":"84.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"170.1","Cytotrophoblasts":"152.2","Langerhans cells":"555.3","Syncytiotrophoblasts":"521.6","T-cells":"92.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"4597.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"4597.2"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"lymphoma":"127.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003796","HPA031383","HPA074467"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB003796":"AB_562261","HPA031383":"AB_2673854","HPA074467":"AB_2686693"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.84e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.03e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.61e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.72e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"}},{"Gene":"CCR8","Gene synonym":["CDw198","CKR-L1","CMKBR8","CMKBRL2","CY6","GPR-CY6","TER1"],"Ensembl":"ENSG00000179934","Gene description":"C-C motif chemokine receptor 8","Uniprot":["P51685"],"Chromosome":"3","Position":"39329709-39333680","Protein class":["CD markers","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"7.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"T-reg":"25.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"T-cells":"25.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"2.9","lymphoma":"5.4","testis cancer":"3.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042383"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042383":"AB_2732497"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-1"}},{"Gene":"CCR9","Gene synonym":["CDw199","GPR-9-6","GPR28"],"Ensembl":"ENSG00000173585","Gene description":"C-C motif chemokine receptor 9","Uniprot":["P51686"],"Chromosome":"3","Position":"45886504-45903175","Protein class":["CD markers","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"lymphoid tissue":"124.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"1.2","T-cells":"2.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"memory B-cell":"24.0","naive B-cell":"15.6","T-reg":"8.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"42","RNA blood lineage specific nTPM":{"B-cells":"24.0","T-cells":"8.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"6.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006839","HPA066879"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"CAB006839":null,"HPA066879":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"}},{"Gene":"CCRL2","Gene synonym":["ACKR5","CKRX","CRAM-A","CRAM-B","HCR"],"Ensembl":"ENSG00000121797","Gene description":"C-C motif chemokine receptor like 2","Uniprot":["O00421"],"Chromosome":"3","Position":"46407166-46412997","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"36.8","Hofbauer cells":"50.5","Langerhans cells":"45.2","Macrophages":"49.2","monocytes":"93.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"6.6"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Prostate - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043238"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043238":"AB_10794924"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.72e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.67e-5"}},{"Gene":"CCT3","Gene synonym":["Cctg","TRIC5"],"Ensembl":"ENSG00000163468","Gene description":"Chaperonin containing TCP1 subunit 3","Uniprot":["P49368"],"Chromosome":"1","Position":"156308968-156367873","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006543"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA006543":"AB_1078426"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.87e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"}},{"Gene":"CD101","Gene synonym":["IGSF2","V7"],"Ensembl":"ENSG00000134256","Gene description":"CD101 molecule","Uniprot":["Q93033"],"Chromosome":"1","Position":"117001750-117036476","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"4.6","intestine":"6.1","lung":"6.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"4.8","Langerhans cells":"4.8","Macrophages":"7.9","monocytes":"20.6","T-cells":"5.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"92.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"dendritic cells":"32.6","granulocytes":"92.7","monocytes":"51.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049527","HPA057763"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"630000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA049527":null,"HPA057763":"AB_2683519"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"}},{"Gene":"CD109","Gene synonym":["CPAMD7","DKFZp762L1111","FLJ38569"],"Ensembl":"ENSG00000156535","Gene description":"CD109 molecule","Uniprot":["Q6YHK3"],"Chromosome":"6","Position":"73695785-73828316","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"parathyroid gland":"330.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"64.7","Basal respiratory cells":"57.3","Basal squamous epithelial cells":"51.7","Endothelial cells":"41.7","Squamous epithelial cells":"47.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Prostate - Endothelial cells","Testis - Early spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008992","HPA015723"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA008992":null,"HPA015723":"AB_2732415"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.65e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.96e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.68e-4"}},{"Gene":"CD151","Gene synonym":["PETA-3","RAPH","SFA-1","TSPAN24"],"Ensembl":"ENSG00000177697","Gene description":"CD151 molecule (Raph blood group)","Uniprot":["P48509"],"Chromosome":"11","Position":"832887-839831","Protein class":["Blood group antigen proteins","CD markers","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Blood group antigen"],"Disease involvement":["Deafness","Epidermolysis bullosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"667.2","Exocrine glandular cells":"860.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002428","HPA011906"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002428":"AB_564129","HPA011906":"AB_1846245"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.46e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.92e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"}},{"Gene":"CD163","Gene synonym":["M130","MM130","SCARI1"],"Ensembl":"ENSG00000177575","Gene description":"CD163 molecule","Uniprot":["Q86VB7"],"Chromosome":"12","Position":"7470811-7503893","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Acute phase","Inflammatory response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"240.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hofbauer cells":"257.8","Kupffer cells":"890.0","Macrophages":"713.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"classical monocyte":"76.1","myeloid DC":"65.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"40","RNA blood lineage specific nTPM":{"dendritic cells":"65.2","monocytes":"76.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"1.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002432","HPA046404","HPA051974"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":903000000,"Blood concentration - Conc. blood MS [pg\/L]":"1600000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002432":"AB_563510","HPA046404":"AB_2679655","HPA051974":"AB_2681678"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.27e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"}},{"Gene":"CD163L1","Gene synonym":["CD163B","M160","SCARI2","WC1"],"Ensembl":"ENSG00000177675","Gene description":"CD163 molecule like 1","Uniprot":["Q9NR16"],"Chromosome":"12","Position":"7346685-7479897","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"21.9","lymphoid tissue":"31.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"28.9","Breast myoepithelial cells":"18.2","Excitatory neurons":"18.6","Inhibitory neurons":"16.2","Melanocytes":"24.4","Sertoli cells":"11.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Macrophages","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015663"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"660000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Centrosome","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA015663":"AB_2072575"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"}},{"Gene":"CD164","Gene synonym":["DFNA66","MGC-24","MUC-24"],"Ensembl":"ENSG00000135535","Gene description":"CD164 molecule","Uniprot":["Q04900"],"Chromosome":"6","Position":"109366514-109382467","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Myogenesis"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"761.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010636"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010636":"AB_1078447"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"}},{"Gene":"CD164L2","Gene synonym":[],"Ensembl":"ENSG00000174950","Gene description":"CD164 molecule like 2","Uniprot":["Q6UWJ8"],"Chromosome":"1","Position":"27379176-27383333","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"19.9","fallopian tube":"30.0","salivary gland":"13.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"60.3","Ionocytes":"28.0","Respiratory ciliated cells":"142.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062915"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA062915":"AB_2684903"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.64e-5"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"}},{"Gene":"CD177","Gene synonym":["HNA2A","NB1","PRV1"],"Ensembl":"ENSG00000204936","Gene description":"CD177 molecule","Uniprot":[],"Chromosome":"19","Position":"43353686-43363172","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"285.9","intestine":"164.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Distal enterocytes":"308.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"27.6"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"3.6","cerebral cortex":"7.7","pons":"2.3"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"8.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"8.7"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"Rhabdoid":"53.7"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2","Prostate - Prostate glandular cells","Skeletal muscle - Neutrophils","Stomach - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041820","HPA046601","HPA077640"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041820":"AB_2677691","HPA046601":"AB_2679716","HPA077640":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.66e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"}},{"Gene":"CD180","Gene synonym":["LY64","Ly78","RP105"],"Ensembl":"ENSG00000134061","Gene description":"CD180 molecule","Uniprot":["Q99467"],"Chromosome":"5","Position":"67179613-67196799","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"23.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"56.5","Hofbauer cells":"69.5","Macrophages":"21.0","Plasma cells":"54.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"77.0","naive B-cell":"78.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"25","RNA blood lineage specific nTPM":{"B-cells":"78.9","dendritic cells":"23.5","monocytes":"34.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"14.3","Myeloma":"11.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Plasma cells","Colon - Macrophages","Heart muscle - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Skeletal muscle - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003740"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Plasma membrane","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Nucleoli","Mitotic spindle"],"Antibody RRID":{"HPA003740":"AB_1078450"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"}},{"Gene":"CD19","Gene synonym":[],"Ensembl":"ENSG00000177455","Gene description":"CD19 molecule","Uniprot":["P15391"],"Chromosome":"16","Position":"28931965-28939342","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"intestine":"33.0","lymphoid tissue":"75.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"130.2","Early spermatids":"49.1","Plasma cells":"31.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"80","RNA blood cell specific nTPM":{"memory B-cell":"138.2","naive B-cell":"172.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"89","RNA blood lineage specific nTPM":{"B-cells":"172.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"Leukemia":"36.7","lymphoma":"69.1"},"RNA tissue cell type enrichment":["Liver - T-cells","Lung - B-cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016110"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016110":"AB_626952"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"}},{"Gene":"CD1A","Gene synonym":["CD1"],"Ensembl":"ENSG00000158477","Gene description":"CD1a molecule","Uniprot":["P06126"],"Chromosome":"1","Position":"158254424-158258269","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"lymphoid tissue":"318.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Langerhans cells":"206.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"25","RNA blood cell specific nTPM":{"classical monocyte":"6.4","intermediate monocyte":"4.2","memory B-cell":"10.1","myeloid DC":"11.4","naive B-cell":"5.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"37","RNA blood lineage specific nTPM":{"B-cells":"10.1","dendritic cells":"11.4","monocytes":"6.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"18","RNA cell line specific nTPM":{"Leukemia":"12.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000009","HPA010734"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000009":"AB_2073290","HPA010734":"AB_1078452"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.37e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"}},{"Gene":"CD1B","Gene synonym":["CD1"],"Ensembl":"ENSG00000158485","Gene description":"CD1b molecule","Uniprot":["P29016"],"Chromosome":"1","Position":"158327951-158331531","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"157","RNA tissue specific nTPM":{"lymphoid tissue":"528.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"37","RNA single cell type specific nTPM":{"Langerhans cells":"202.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"myeloid DC":"19.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"19.2"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"497","RNA cell line specific nTPM":{"Leukemia":"49.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021824"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA021824":"AB_1846262"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"}},{"Gene":"CD1C","Gene synonym":["CD1"],"Ensembl":"ENSG00000158481","Gene description":"CD1c molecule","Uniprot":["P29017"],"Chromosome":"1","Position":"158289923-158294774","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"lymphoid tissue":"130.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Langerhans cells":"750.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"84.1","myeloid DC":"324.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"B-cells":"84.1","dendritic cells":"324.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"34","RNA cell line specific nTPM":{"Leukemia":"5.0","lymphoma":"4.6"},"RNA tissue cell type enrichment":["Liver - T-cells","Skin - Langerhans cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068359"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA068359":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.79e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"}},{"Gene":"CD1D","Gene synonym":[],"Ensembl":"ENSG00000158473","Gene description":"CD1d molecule","Uniprot":["P15813"],"Chromosome":"1","Position":"158178030-158186427","Protein class":["Cancer-related genes","CD markers","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"18.2","liver":"15.3","lymphoid tissue":"23.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"20.6","Hofbauer cells":"30.9","Kupffer cells":"55.9","Macrophages":"35.8","monocytes":"40.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"139.0","intermediate monocyte":"63.8","myeloid DC":"139.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"139.3","monocytes":"139.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"3.6","lymphoma":"2.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016107","HPA072662"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"880000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB016107":"AB_626960","HPA072662":"AB_2686545"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"}},{"Gene":"CD1E","Gene synonym":[],"Ensembl":"ENSG00000158488","Gene description":"CD1e molecule","Uniprot":["P15812"],"Chromosome":"1","Position":"158353696-158357553","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"69","RNA tissue specific nTPM":{"lymphoid tissue":"962.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Langerhans cells":"758.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"myeloid DC":"62.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"dendritic cells":"62.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"305","RNA cell line specific nTPM":{"Leukemia":"63.0"},"RNA tissue cell type enrichment":["Skin - Langerhans cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057769","HPA070634"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA057769":"AB_2683522","HPA070634":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"}},{"Gene":"CD2","Gene synonym":["SRBC"],"Ensembl":"ENSG00000116824","Gene description":"CD2 molecule","Uniprot":["P06729"],"Chromosome":"1","Position":"116754430-116769229","Protein class":["CD markers","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"lymphoid tissue":"249.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"NK-cells":"202.8","T-cells":"464.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"gdT-cell":"421.8","MAIT T-cell":"403.1","memory CD4 T-cell":"610.2","memory CD8 T-cell":"714.1","naive CD4 T-cell":"316.3","naive CD8 T-cell":"486.2","NK-cell":"1108.0","T-reg":"655.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"NK-cells":"1108.0","T-cells":"714.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"88","RNA cell line specific nTPM":{"Leukemia":"10.9","lymphoma":"16.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Kidney - T-cells","Liver - T-cells","Lung - T-cells","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Stomach - T-cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002430","HPA003883"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Golgi apparatus"],"Antibody RRID":{"CAB002430":"AB_442057","HPA003883":"AB_1846263"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.36e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.47e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.69e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.46e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.97e-5"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.72e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.82e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-3"}},{"Gene":"CD200","Gene synonym":["MOX1","MOX2","MRC","OX-2"],"Ensembl":"ENSG00000091972","Gene description":"CD200 molecule","Uniprot":["P41217"],"Chromosome":"3","Position":"112332347-112362812","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endothelial cells":"43.9","Excitatory neurons":"53.7","Glandular and luminal cells":"41.2","Inhibitory neurons":"54.3","Syncytiotrophoblasts":"73.4","Thymic epithelial cells":"89.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"memory B-cell":"30.7","naive B-cell":"83.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"B-cells":"83.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"32.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast myoepithelial cells","Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031149"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"26000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031149":"AB_10600694"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"}},{"Gene":"CD200R1","Gene synonym":["CD200R","HCRTR2","MOX2R","OX2R"],"Ensembl":"ENSG00000163606","Gene description":"CD200 receptor 1","Uniprot":["Q8TD46"],"Chromosome":"3","Position":"112921205-112975103","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"7.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"12.8","granulocytes":"21.5","Hofbauer cells":"29.9","Langerhans cells":"23.6","Macrophages":"10.0","T-cells":"12.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"234.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"234.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"cervical cancer":"17.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068512"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA068512":"AB_2732784"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"}},{"Gene":"CD200R1L","Gene synonym":["CD200R2","CD200RLa"],"Ensembl":"ENSG00000206531","Gene description":"CD200 receptor 1 like","Uniprot":["Q6Q8B3"],"Chromosome":"3","Position":"112815709-112846856","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"testis":"2.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"36","RNA single cell type specific nTPM":{"Early spermatids":"29.0","Late spermatids":"45.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"379","RNA blood cell specific nTPM":{"basophil":"85.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"455","RNA blood lineage specific nTPM":{"granulocytes":"85.0"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"}},{"Gene":"CD207","Gene synonym":["CLEC4K","Langerin"],"Ensembl":"ENSG00000116031","Gene description":"CD207 molecule","Uniprot":["Q9UJ71"],"Chromosome":"2","Position":"70830211-70835816","Protein class":["CD markers","Disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"87.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Langerhans cells":"15.2","Macrophages":"12.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"myeloid DC":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"1.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"1.4"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002222","HPA011216"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002222":"AB_563850","HPA011216":"AB_1078453"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"}},{"Gene":"CD209","Gene synonym":["CDSIGN","CLEC4L","DC-SIGN","DC-SIGN1"],"Ensembl":"ENSG00000090659","Gene description":"CD209 molecule","Uniprot":["Q9NNX6"],"Chromosome":"19","Position":"7739993-7747564","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Cell adhesion","Endocytosis","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"34.2","placenta":"22.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Langerhans cells":"15.0","Macrophages":"22.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"1.4","intermediate monocyte":"1.4","myeloid DC":"1.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"1.2","monocytes":"1.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"1.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Skeletal muscle - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032436","CAB033831"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3100000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB032436":"AB_639039","CAB033831":"AB_1121347"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"CD22","Gene synonym":["SIGLEC-2","SIGLEC2"],"Ensembl":"ENSG00000012124","Gene description":"CD22 molecule","Uniprot":["P20273"],"Chromosome":"19","Position":"35319261-35347361","Protein class":["CD markers","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"141.3","lymphoid tissue":"230.2","ovary":"132.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"B-cells":"157.6","granulocytes":"47.4","Granulosa cells":"51.9","Oligodendrocytes":"86.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"24","RNA blood cell specific nTPM":{"memory B-cell":"97.6","naive B-cell":"120.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"B-cells":"120.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"lymphoma":"197.3"},"RNA tissue cell type enrichment":["Colon - Mast cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002418","HPA024353","HPA066523"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002418":"AB_563529","HPA024353":"AB_10600695","HPA066523":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"}},{"Gene":"CD226","Gene synonym":["DNAM-1","DNAM1","PTA1","TLiSA1"],"Ensembl":"ENSG00000150637","Gene description":"CD226 molecule","Uniprot":["Q15762"],"Chromosome":"18","Position":"69831158-69961803","Protein class":["CD markers","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"20.2","parathyroid gland":"62.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"21.9","NK-cells":"103.3","Oligodendrocytes":"25.1","Schwann cells":"30.0","T-cells":"52.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"gdT-cell":"36.6","MAIT T-cell":"13.4","memory CD4 T-cell":"28.8","memory CD8 T-cell":"22.5","naive CD4 T-cell":"15.8","naive CD8 T-cell":"17.3","NK-cell":"29.7","T-reg":"11.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"NK-cells":"29.7","T-cells":"36.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"7.1","lymphoma":"10.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Colon - T-cells","Prostate - T-cells","Stomach - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015715","HPA015865"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Centriolar satellite"],"Antibody RRID":{"HPA015715":"AB_1846278","HPA015865":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"}},{"Gene":"CD244","Gene synonym":["2B4","NAIL","NKR2B4","Nmrk","SLAMF4"],"Ensembl":"ENSG00000122223","Gene description":"CD244 molecule","Uniprot":["Q9BZW8"],"Chromosome":"1","Position":"160830160-160862887","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"10.0","lymphoid tissue":"16.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"12.7","Macrophages":"7.4","monocytes":"15.7","NK-cells":"40.4","T-cells":"18.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"472.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"472.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"Leukemia":"15.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - Mesothelial cells","Breast - T-cells","Heart muscle - T-cells","Kidney - T-cells","Lung - NK-cells (Lung)","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"CD247","Gene synonym":["CD3H","CD3Q","CD3Z"],"Ensembl":"ENSG00000198821","Gene description":"CD247 molecule","Uniprot":["P20963"],"Chromosome":"1","Position":"167430640-167518610","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"bone marrow":"49.0","lymphoid tissue":"179.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"NK-cells":"788.2","T-cells":"243.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"25","RNA blood cell specific nTPM":{"gdT-cell":"376.4","MAIT T-cell":"208.9","memory CD4 T-cell":"190.0","memory CD8 T-cell":"219.7","naive CD4 T-cell":"237.8","naive CD8 T-cell":"195.1","NK-cell":"225.3","T-reg":"254.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"NK-cells":"225.3","T-cells":"376.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"24","RNA cell line specific nTPM":{"Leukemia":"23.3","lymphoma":"24.2","Myeloma":"17.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - NK-cells (Liver)","Lung - NK-cells (Lung)","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004651","HPA008750"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004651":"AB_425347","HPA008750":"AB_1857863"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.12e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.63e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.98e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.94e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-3"}},{"Gene":"CD248","Gene synonym":["CD164L1","TEM1"],"Ensembl":"ENSG00000174807","Gene description":"CD248 molecule","Uniprot":["Q9HCU0"],"Chromosome":"11","Position":"66314494-66317044","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"237.3","breast":"155.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Endometrial stromal cells":"159.7","Fibroblasts":"187.7","Leydig cells":"76.7","Smooth muscle cells":"67.2","Thymic epithelial cells":"53.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"naive CD8 T-cell":"21.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"144","RNA blood lineage specific nTPM":{"T-cells":"21.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bone cancer":"145.3","Neuroblastoma":"37.3","Sarcoma":"72.9"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Colon - Fibroblasts","Liver - Hepatic stellate cells","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Fibroblast_2","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051856"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"43000000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA051856":"AB_2681640"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.69e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"}},{"Gene":"CD27","Gene synonym":["S152","TNFRSF7","Tp55"],"Ensembl":"ENSG00000139193","Gene description":"CD27 molecule","Uniprot":["P26842"],"Chromosome":"12","Position":"6444955-6451718","Protein class":["Cancer-related genes","CD markers","Disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"147.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"B-cells":"114.0","Plasma cells":"407.5","T-cells":"108.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"640.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"293.4","T-cells":"640.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"lymphoma":"76.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Breast - Plasma cells","Lung - Plasma cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002420","HPA038936"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002420":"AB_563539","HPA038936":"AB_2676278"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.77e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.65e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.50e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.19e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"}},{"Gene":"CD274","Gene synonym":["B7-H","B7-H1","B7H1","PD-L1","PDCD1LG1","PDL1"],"Ensembl":"ENSG00000120217","Gene description":"CD274 molecule","Uniprot":["Q9NZQ7"],"Chromosome":"9","Position":"5450503-5470566","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"16.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"31.5","granulocytes":"32.3","Langerhans cells":"63.4","Syncytiotrophoblasts":"55.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"6.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"6.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003528","CAB076385"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Plasma membrane","Actin filaments"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB076385":"AB_2687655","HPA003528":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.89e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.64e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"}},{"Gene":"CD276","Gene synonym":["B7-H3","B7H3","B7RP-2"],"Ensembl":"ENSG00000103855","Gene description":"CD276 molecule","Uniprot":["Q5ZPR3"],"Chromosome":"15","Position":"73683966-73714514","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"244.3","Hofbauer cells":"69.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Skin - Fibroblast_2","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009285","HPA017139","CAB017826"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB017826":null,"HPA009285":"AB_1078258","HPA017139":"AB_1845246"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.81e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"}},{"Gene":"CD28","Gene synonym":[],"Ensembl":"ENSG00000178562","Gene description":"CD28 molecule","Uniprot":["P10747"],"Chromosome":"2","Position":"203706475-203738912","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"30.8","placenta":"14.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Hofbauer cells":"31.4","T-cells":"58.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"101.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"T-cells":"101.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"Myeloma":"98.7"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Kidney - T-cells","Skin - T-cells","Testis - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.0"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070003"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA070003":"AB_2686226"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"}},{"Gene":"CD300A","Gene synonym":["CMRF-35-H9","CMRF35H","IGSF12","IRC1","IRC2","Irp60"],"Ensembl":"ENSG00000167851","Gene description":"CD300a molecule","Uniprot":["Q9UGN4"],"Chromosome":"17","Position":"74466399-74484794","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"95.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"56.7","Hofbauer cells":"137.6","Kupffer cells":"73.8","Macrophages":"75.3","monocytes":"134.1","NK-cells":"141.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"38.2","Myeloma":"11.4"},"RNA tissue cell type enrichment":["Liver - Kupffer cells","Stomach - Macrophages","Testis - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010971","HPA011645"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA010971":null,"HPA011645":"AB_1846988"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"}},{"Gene":"CD300C","Gene synonym":["CMRF-35A","CMRF35","CMRF35A","IGSF16","LIR"],"Ensembl":"ENSG00000167850","Gene description":"CD300c molecule","Uniprot":["Q08708"],"Chromosome":"17","Position":"74541073-74546115","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"9.7","lung":"8.4","lymphoid tissue":"7.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hofbauer cells":"43.1","Kupffer cells":"12.5","Langerhans cells":"16.2","Macrophages":"27.4","monocytes":"46.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"228.3","non-classical monocyte":"242.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"5.3","lymphoma":"5.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Lung - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014523","HPA060349"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles","Mitochondria"],"Antibody RRID":{"HPA014523":"AB_1846293","HPA060349":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.53e-5"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"CD300E","Gene synonym":["CD300LE","CLM2","IREM2"],"Ensembl":"ENSG00000186407","Gene description":"CD300e molecule","Uniprot":["Q496F6"],"Chromosome":"17","Position":"74609885-74623738","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"48.1","lymphoid tissue":"37.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"50.8","Kupffer cells":"116.5","Macrophages":"83.9","monocytes":"216.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"3.7"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"88.0","intermediate monocyte":"135.1","non-classical monocyte":"148.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"monocytes":"148.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"1.3"},"RNA tissue cell type enrichment":["Colon - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015570"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015570":"AB_1846294"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"}},{"Gene":"CD300LB","Gene synonym":["CLM7","TREM5"],"Ensembl":"ENSG00000178789","Gene description":"CD300 molecule like family member b","Uniprot":["A8K4G0"],"Chromosome":"17","Position":"74521174-74531475","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"7.8","brain":"16.3","lymphoid tissue":"8.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"dendritic cells":"14.9","Hofbauer cells":"13.3","Kupffer cells":"21.3","Langerhans cells":"9.5","Macrophages":"14.8","monocytes":"11.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"16.3"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"75.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"53","RNA blood lineage specific nTPM":{"dendritic cells":"25.0","granulocytes":"75.9","monocytes":"31.7"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"1.8"},"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060449"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA060449":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"}},{"Gene":"CD300LD","Gene synonym":["CD300D","CMRF35A4"],"Ensembl":"ENSG00000204345","Gene description":"CD300 molecule like family member d","Uniprot":["Q6UXZ3"],"Chromosome":"17","Position":"74579365-74592283","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"4.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"4.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027756"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027756":"AB_10601097"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CD300LF","Gene synonym":["CD300f","CLM1","IGSF13","IREM1","NKIR"],"Ensembl":"ENSG00000186074","Gene description":"CD300 molecule like family member f","Uniprot":["Q8TDQ1"],"Chromosome":"17","Position":"74694311-74712978","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"27.0","lung":"17.7","lymphoid tissue":"28.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hofbauer cells":"41.6","Kupffer cells":"30.0","Macrophages":"39.0","monocytes":"62.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"234.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"43","RNA blood lineage specific nTPM":{"dendritic cells":"63.8","granulocytes":"234.2","monocytes":"193.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"62","RNA cell line specific nTPM":{"Leukemia":"18.8"},"RNA tissue cell type enrichment":["Lung - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013712"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013712":"AB_2668874"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"}},{"Gene":"CD300LG","Gene synonym":["CLM9","Trem4"],"Ensembl":"ENSG00000161649","Gene description":"CD300 molecule like family member g","Uniprot":["Q6UXG3"],"Chromosome":"17","Position":"43847148-43863639","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"133.6","breast":"111.8","placenta":"58.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Adipocytes":"512.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"}},{"Gene":"CD302","Gene synonym":["BIMLEC","CLEC13A","DCL-1","KIAA0022"],"Ensembl":"ENSG00000241399","Gene description":"CD302 molecule","Uniprot":["Q8IX05"],"Chromosome":"2","Position":"159768628-159798255","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"193.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"317.5","Kupffer cells":"276.3","Langerhans cells":"130.6","Macrophages":"206.1","monocytes":"167.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"215","RNA blood lineage specific nTPM":{"dendritic cells":"24.4","granulocytes":"32.2","monocytes":"33.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-3"}},{"Gene":"CD320","Gene synonym":["8D6","8D6A"],"Ensembl":"ENSG00000167775","Gene description":"CD320 molecule","Uniprot":["Q9NPF0"],"Chromosome":"19","Position":"8302127-8308358","Protein class":["CD markers","Disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"416.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014500","HPA073489"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"61000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA014500":"AB_1846295","HPA073489":"AB_2686609"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.02e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"}},{"Gene":"CD33","Gene synonym":["FLJ00391","p67","SIGLEC-3","SIGLEC3"],"Ensembl":"ENSG00000105383","Gene description":"CD33 molecule","Uniprot":["P20138"],"Chromosome":"19","Position":"51225064-51243860","Protein class":["CD markers","FDA approved drug targets","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"32.4","lymphoid tissue":"23.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"granulocytes":"68.6","Hofbauer cells":"91.5","Kupffer cells":"67.0","Langerhans cells":"50.7","Macrophages":"62.0","monocytes":"91.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"classical monocyte":"166.5","intermediate monocyte":"122.0","myeloid DC":"213.5","non-classical monocyte":"57.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"213.5","monocytes":"166.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"52.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011442","HPA035832","HPA064807","CAB079996"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3400000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB011442":null,"CAB079996":null,"HPA035832":"AB_2674808","HPA064807":"AB_2685356"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"}},{"Gene":"CD34","Gene synonym":[],"Ensembl":"ENSG00000174059","Gene description":"CD34 molecule","Uniprot":["P28906"],"Chromosome":"1","Position":"207880972-207911402","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Adipocytes":"301.7","Endothelial cells":"261.2","Fibroblasts":"116.9","Leydig cells":"144.5","Peritubular cells":"120.1","Thymic epithelial cells":"170.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Leukemia":"59.0","Rhabdoid":"112.2","Sarcoma":"91.0"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Pancreas - Endothelial cells","Prostate - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000018","HPA036722","HPA036723"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"93000000","Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB000018":"AB_2063006","HPA036722":"AB_2675271","HPA036723":"AB_2675272"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.93e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.47e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"}},{"Gene":"CD36","Gene synonym":["FAT","GP3B","GP4","GPIV","SCARB3"],"Ensembl":"ENSG00000135218","Gene description":"CD36 molecule","Uniprot":["P16671"],"Chromosome":"7","Position":"80369575-80679277","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Lipid transport","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"1533.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"2875.9","Cardiomyocytes":"884.2","Hofbauer cells":"1267.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"962.6","intermediate monocyte":"270.6","myeloid DC":"507.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"46","RNA blood lineage specific nTPM":{"dendritic cells":"507.1","monocytes":"962.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"55.4"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Colon - Endothelial cells","Liver - Sinusoid Endothelial cells","Stomach - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"16.9"},"Antibody":["HPA002018","CAB025866","HPA071026"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5300000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB025866":null,"HPA002018":"AB_1078464","HPA071026":"AB_2732170"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.47e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"}},{"Gene":"CD37","Gene synonym":["TSPAN26"],"Ensembl":"ENSG00000104894","Gene description":"CD37 molecule","Uniprot":["P11049"],"Chromosome":"19","Position":"49335171-49343335","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"155.2","intestine":"116.3","lymphoid tissue":"235.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1698.7","dendritic cells":"539.1","granulocytes":"459.9","Hofbauer cells":"485.4","Langerhans cells":"414.6","monocytes":"749.0","NK-cells":"383.4","T-cells":"394.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"70.9","lymphoma":"194.7"},"RNA tissue cell type enrichment":["Breast - T-cells","Prostate - T-cells","Skeletal muscle - Macrophages","Skin - T-cells","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002492","HPA032120","HPA032121"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB002492":"AB_563554","HPA032120":"AB_2674162","HPA032121":"AB_2674163"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.51e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"}},{"Gene":"CD38","Gene synonym":[],"Ensembl":"ENSG00000004468","Gene description":"CD38 molecule","Uniprot":["P28907"],"Chromosome":"4","Position":"15778275-15853232","Protein class":["Cancer-related genes","CD markers","Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Receptor","Transferase"],"Disease involvement":["Cancer-related genes","Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"63.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Plasma cells":"372.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"18.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"9.9","dendritic cells":"5.8","NK-cells":"18.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"Leukemia":"26.6","lymphoma":"45.9","Myeloma":"41.7"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002493","HPA022132","CAB025255","HPA052381"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002493":"AB_563556","CAB025255":null,"HPA022132":"AB_1846300","HPA052381":"AB_2681807"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.68e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-6"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"}},{"Gene":"CD3D","Gene synonym":["T3D"],"Ensembl":"ENSG00000167286","Gene description":"CD3d molecule","Uniprot":["P04234"],"Chromosome":"11","Position":"118339075-118342705","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"30","RNA tissue specific nTPM":{"lymphoid tissue":"906.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"T-cells":"664.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"52","RNA blood cell specific nTPM":{"gdT-cell":"1462.4","MAIT T-cell":"990.0","memory CD4 T-cell":"1206.1","memory CD8 T-cell":"1368.7","naive CD4 T-cell":"1091.4","naive CD8 T-cell":"1338.9","T-reg":"1660.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"66","RNA blood lineage specific nTPM":{"T-cells":"1660.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"234.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Kidney - T-cells","Liver - T-cells","Lung - T-cells","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013055","HPA071778"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB013055":null,"HPA071778":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.00e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.46e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.73e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.07e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.16e-4"}},{"Gene":"CD3E","Gene synonym":[],"Ensembl":"ENSG00000198851","Gene description":"CD3e molecule","Uniprot":["P07766"],"Chromosome":"11","Position":"118304730-118316175","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"lymphoid tissue":"640.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"NK-cells":"218.3","T-cells":"639.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"26","RNA blood cell specific nTPM":{"gdT-cell":"490.6","MAIT T-cell":"420.8","memory CD4 T-cell":"414.4","memory CD8 T-cell":"463.5","naive CD4 T-cell":"491.7","naive CD8 T-cell":"501.3","NK-cell":"202.2","T-reg":"426.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"NK-cells":"202.2","T-cells":"501.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"123.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - T-cells","Lung - T-cells","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Stomach - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000010","HPA040957","HPA043955","CAB072863","CAB072864"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Endoplasmic reticulum","Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB000010":"AB_2631163","CAB072863":"AB_2665707","CAB072864":"AB_2665708","HPA040957":"AB_2677222","HPA043955":"AB_2678747"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.72e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.30e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"}},{"Gene":"CD3G","Gene synonym":[],"Ensembl":"ENSG00000160654","Gene description":"CD3g molecule","Uniprot":["P09693"],"Chromosome":"11","Position":"118344344-118355161","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"lymphoid tissue":"94.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"NK-cells":"96.8","T-cells":"326.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"21","RNA blood cell specific nTPM":{"gdT-cell":"229.0","MAIT T-cell":"135.6","memory CD4 T-cell":"187.3","memory CD8 T-cell":"197.3","naive CD4 T-cell":"192.6","naive CD8 T-cell":"241.7","T-reg":"200.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"T-cells":"241.7"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"19.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Colon - T-cells","Kidney - T-cells","Liver - T-cells","Lung - T-cells","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Stomach - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017520","HPA038494"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB017520":"AB_831094","HPA038494":"AB_2676044"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.33e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.61e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.00e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.33e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"}},{"Gene":"CD4","Gene synonym":[],"Ensembl":"ENSG00000010610","Gene description":"CD4 molecule","Uniprot":["P01730"],"Chromosome":"12","Position":"6786858-6820799","Protein class":["CD markers","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"152.9","lymphoid tissue":"219.3","parathyroid gland":"173.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"230.8","Hofbauer cells":"153.9","Kupffer cells":"85.4","Langerhans cells":"100.8","Macrophages":"131.9","monocytes":"150.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"18","RNA blood cell specific nTPM":{"classical monocyte":"247.3","intermediate monocyte":"241.4","memory CD4 T-cell":"153.4","myeloid DC":"166.3","naive CD4 T-cell":"128.1","non-classical monocyte":"204.2","plasmacytoid DC":"263.8","T-reg":"154.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"dendritic cells":"263.8","monocytes":"247.3","T-cells":"154.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"40","RNA cell line specific nTPM":{"Leukemia":"41.4","lymphoma":"38.1","Myeloma":"22.5"},"RNA tissue cell type enrichment":["Colon - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"14","RNA mouse brain regional specific nTPM":{"basal ganglia":"46.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000011","HPA004252","HPA004472","CAB068180"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB000011":"AB_442062","CAB068180":"AB_2665653","HPA004252":"AB_1078466","HPA004472":"AB_1078465"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.16e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"}},{"Gene":"CD40","Gene synonym":["Bp50","p50","TNFRSF5"],"Ensembl":"ENSG00000101017","Gene description":"CD40 molecule","Uniprot":["P25942"],"Chromosome":"20","Position":"46118278-46129863","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"127.8","Basal respiratory cells":"120.7","Langerhans cells":"239.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"139.4","naive B-cell":"157.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"157.9","monocytes":"43.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"90.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002495","HPA031567","HPA031568","CAB072868"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":705000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002495":"AB_563562","CAB072868":"AB_2665719","HPA031567":"AB_2673936","HPA031568":"AB_2673937"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.48e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"}},{"Gene":"CD40LG","Gene synonym":["CD154","CD40L","gp39","hCD40L","HIGM1","IMD3","TNFSF5","TRAP"],"Ensembl":"ENSG00000102245","Gene description":"CD40 ligand","Uniprot":["P29965"],"Chromosome":"X","Position":"136648158-136660390","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"15.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"T-cells":"77.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"26.3","MAIT T-cell":"64.1","memory CD4 T-cell":"80.5","naive CD4 T-cell":"76.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"39","RNA blood lineage specific nTPM":{"T-cells":"80.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"Leukemia":"2.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Colon - T-cells","Kidney - T-cells","Liver - T-cells","Lung - T-cells","Skin - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045827","HPA072480"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":776000,"Blood concentration - Conc. blood MS [pg\/L]":"20000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA045827":"AB_10959606","HPA072480":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"}},{"Gene":"CD44","Gene synonym":["CD44R","CSPG8","HCELL","IN","MC56","MDU2","MDU3","MIC4","Pgp1"],"Ensembl":"ENSG00000026508","Gene description":"CD44 molecule (Indian blood group)","Uniprot":["P16070"],"Chromosome":"11","Position":"35138882-35232402","Protein class":["Blood group antigen proteins","Cancer-related genes","CD markers","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Blood group antigen","Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"504.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"952.6","Exocrine glandular cells":"924.6","granulocytes":"1130.6","Langerhans cells":"2369.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Prostate - Urothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000112","CAB000316","HPA005785"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB000112":null,"CAB000316":"AB_2076596","HPA005785":"AB_1078467"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.78e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"}},{"Gene":"CD46","Gene synonym":["MCP","MGC26544","MIC10","TLX","TRA2.10"],"Ensembl":"ENSG00000117335","Gene description":"CD46 molecule","Uniprot":["P15529"],"Chromosome":"1","Position":"207752054-207795513","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Complement pathway","Fertilization","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Mucus glandular cells":"513.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"296.7","eosinophil":"382.4","neutrophil":"401.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"401.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010401","HPA016903"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010401":"AB_2291289","HPA016903":"AB_1846309"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.54e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.38e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"}},{"Gene":"CD47","Gene synonym":["IAP","MER6","OA3"],"Ensembl":"ENSG00000196776","Gene description":"CD47 molecule","Uniprot":["Q08722"],"Chromosome":"3","Position":"108043091-108091862","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"522.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016055","HPA044659"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"49000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB016055":"AB_627086","HPA044659":"AB_2679040"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.44e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.29e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"}},{"Gene":"CD48","Gene synonym":["BCM1","BLAST","hCD48","mCD48","SLAMF2"],"Ensembl":"ENSG00000117091","Gene description":"CD48 molecule","Uniprot":["P09326"],"Chromosome":"1","Position":"160678746-160711831","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"148.4","lymphoid tissue":"283.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"361.7","granulocytes":"198.2","Hofbauer cells":"226.3","Kupffer cells":"257.1","Macrophages":"195.3","monocytes":"853.5","NK-cells":"408.9","Schwann cells":"201.6","T-cells":"432.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"207.9","Myeloma":"445.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Kidney - T-cells","Prostate - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002497","HPA055146"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli fibrillar center","Cytosol"],"Antibody RRID":{"CAB002497":"AB_563586","HPA055146":"AB_2682716"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.91e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.17e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"}},{"Gene":"CD5","Gene synonym":["LEU1","T1"],"Ensembl":"ENSG00000110448","Gene description":"CD5 molecule","Uniprot":["P06127"],"Chromosome":"11","Position":"61102489-61127852","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"46.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"T-cells":"56.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"138.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"T-cells":"138.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Leukemia":"17.2","lymphoma":"28.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - T-cells","Lung - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015392","CAB020308","HPA043416","HPA060839"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015392":"AB_2075324","CAB020308":null,"HPA043416":"AB_2678472","HPA060839":"AB_2684376"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.05e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.16e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.00e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.41e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.94e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"CD52","Gene synonym":["CDW52","EDDM5","HE5"],"Ensembl":"ENSG00000169442","Gene description":"CD52 molecule","Uniprot":["P31358"],"Chromosome":"1","Position":"26317958-26320523","Protein class":["Cancer-related genes","CD markers","FDA approved drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"epididymis":"36173.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1905.6","Hofbauer cells":"979.8","Langerhans cells":"748.0","Macrophages":"564.3","monocytes":"1697.8","NK-cells":"487.7","T-cells":"1243.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"272.6","lymphoma":"602.8"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Breast - T-cells","Lung - Macrophages","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.06e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.45e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.85e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"}},{"Gene":"CD53","Gene synonym":["MOX44","TSPAN25"],"Ensembl":"ENSG00000143119","Gene description":"CD53 molecule","Uniprot":["P19397"],"Chromosome":"1","Position":"110871188-110899922","Protein class":["CD markers","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"448.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"333.8","dendritic cells":"239.0","Hofbauer cells":"395.4","Kupffer cells":"347.0","Langerhans cells":"203.1","Macrophages":"287.0","monocytes":"398.6","NK-cells":"431.6","T-cells":"288.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"71","RNA cell line specific nTPM":{"Leukemia":"172.3","lymphoma":"257.3","Myeloma":"140.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Liver - Kupffer cells","Pancreas - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047216"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047216":"AB_2679986"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.60e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"}},{"Gene":"CD55","Gene synonym":["CR","CROM","DAF","TC"],"Ensembl":"ENSG00000196352","Gene description":"CD55 molecule (Cromer blood group)","Uniprot":["P08174"],"Chromosome":"1","Position":"207321532-207386804","Protein class":["Blood group antigen proteins","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Blood group antigen","Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"1461.4","monocytes":"950.6","Syncytiotrophoblasts":"882.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"662.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002190","CAB010454","HPA024386"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":32300000,"Blood concentration - Conc. blood MS [pg\/L]":"360000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010454":"AB_2075970","HPA002190":"AB_1078472","HPA024386":"AB_1846319"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"}},{"Gene":"CD58","Gene synonym":["LFA3"],"Ensembl":"ENSG00000116815","Gene description":"CD58 molecule","Uniprot":["P19256"],"Chromosome":"1","Position":"116514534-116571039","Protein class":["CD markers","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"139.6","Langerhans cells":"245.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6500000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.32e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.60e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"}},{"Gene":"CD59","Gene synonym":["16.3A5","EJ16","EJ30","EL32","G344","MIC11","MIN1","MIN2","MIN3","MSK21","p18-20"],"Ensembl":"ENSG00000085063","Gene description":"CD59 molecule (CD59 blood group)","Uniprot":["P13987"],"Chromosome":"11","Position":"33703010-33736479","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"1313.6","Melanocytes":"1635.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001448","HPA026494"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB001448":"AB_563604","HPA026494":"AB_1846321"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.81e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.10e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.92e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.39e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.03e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"}},{"Gene":"CD6","Gene synonym":["Tp120"],"Ensembl":"ENSG00000013725","Gene description":"CD6 molecule","Uniprot":["P30203"],"Chromosome":"11","Position":"60971680-61020377","Protein class":["CD markers","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Cell adhesion","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"13.6","lymphoid tissue":"43.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"NK-cells":"40.8","T-cells":"99.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"33","RNA blood cell specific nTPM":{"gdT-cell":"27.7","MAIT T-cell":"24.7","memory CD4 T-cell":"51.4","memory CD8 T-cell":"48.4","naive CD4 T-cell":"34.4","naive CD8 T-cell":"25.2","T-reg":"25.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"51","RNA blood lineage specific nTPM":{"T-cells":"51.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Leukemia":"10.2","lymphoma":"14.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - T-cells","Lung - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002489","CAB016252"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":5270000,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002489":"AB_563605","CAB016252":"AB_631163"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.95e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.57e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.41e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.10e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.82e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"}},{"Gene":"CD63","Gene synonym":["ME491","MLA1","TSPAN30"],"Ensembl":"ENSG00000135404","Gene description":"CD63 molecule","Uniprot":["P08962"],"Chromosome":"12","Position":"55725323-55729707","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1857.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010088","CAB026356","HPA073506"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB026356":"AB_629864","HPA010088":"AB_1846323","HPA073506":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.37e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"}},{"Gene":"CD68","Gene synonym":["DKFZp686M18236","GP110","LAMP4","macrosialin","SCARD1"],"Ensembl":"ENSG00000129226","Gene description":"CD68 molecule","Uniprot":["P34810"],"Chromosome":"17","Position":"7579491-7582111","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"358.0","lymphoid tissue":"370.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"226.4","Kupffer cells":"162.8","Langerhans cells":"81.8","Macrophages":"192.6","Proximal enterocytes":"196.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"3255.5","intermediate monocyte":"3655.9","non-classical monocyte":"3740.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"1378.6","monocytes":"3740.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Lung - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000051","CAB000066","HPA048982","CAB072861","CAB072862"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB000051":"AB_2314148","CAB000066":"AB_2074844","CAB072861":"AB_2665705","CAB072862":"AB_2665706","HPA048982":"AB_2680587"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"}},{"Gene":"CD69","Gene synonym":["CLEC2C"],"Ensembl":"ENSG00000110848","Gene description":"CD69 molecule","Uniprot":["Q07108"],"Chromosome":"12","Position":"9752486-9760901","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"169.1","lymphoid tissue":"94.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"B-cells":"947.5","granulocytes":"1937.7","NK-cells":"517.3","T-cells":"1179.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"NK-cells":"26.7","T-cells":"30.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"44.2","lymphoma":"26.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Kidney - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002503","HPA050525"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002503":"AB_563625","HPA050525":"AB_2681157"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.31e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.87e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"}},{"Gene":"CD7","Gene synonym":["GP40","LEU-9","Tp40","TP41"],"Ensembl":"ENSG00000173762","Gene description":"CD7 molecule","Uniprot":["P09564"],"Chromosome":"17","Position":"82314868-82317608","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"28.6","lymphoid tissue":"53.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"NK-cells":"1172.5","T-cells":"544.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"231.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"NK-cells":"231.5","T-cells":"71.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"49.8","liver cancer":"16.2","Myeloma":"24.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Heart muscle - T-cells","Liver - NK-cells (Liver)","Lung - NK-cells (Lung)","Pancreas - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"3.2"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002594","HPA039079"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002594":null,"HPA039079":"AB_2676337"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.51e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.03e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.69e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.75e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"}},{"Gene":"CD70","Gene synonym":["CD27L","CD27LG","TNFSF7"],"Ensembl":"ENSG00000125726","Gene description":"CD70 molecule","Uniprot":["P32970"],"Chromosome":"19","Position":"6583183-6604103","Protein class":["Cancer-related genes","CD markers","Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"3.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"47.1","Basal respiratory cells":"9.6","Fibroblasts":"8.0","Langerhans cells":"15.9","Plasma cells":"22.1","T-cells":"14.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"renal cancer":"24.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"44.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"35","RNA blood lineage specific nTPM":{"B-cells":"24.2","T-cells":"44.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"350.0"},"RNA tissue cell type enrichment":["Thyroid - T-cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"25","RNA mouse brain regional specific nTPM":{"cerebellum":"11.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046582"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA046582":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.29e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.22e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"}},{"Gene":"CD72","Gene synonym":["CD72b","LYB2"],"Ensembl":"ENSG00000137101","Gene description":"CD72 molecule","Uniprot":["P21854"],"Chromosome":"9","Position":"35609979-35646810","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"lymphoid tissue":"65.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"82.0","dendritic cells":"17.4","Hofbauer cells":"18.3","Langerhans cells":"17.0","Macrophages":"17.9","monocytes":"18.5","NK-cells":"21.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"memory B-cell":"232.9","naive B-cell":"413.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"B-cells":"413.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"25","RNA cell line specific nTPM":{"Leukemia":"21.9","lymphoma":"36.3"},"RNA tissue cell type enrichment":["Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"basal ganglia":"4.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002505","HPA044658"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB002505":"AB_563629","HPA044658":"AB_2679039"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"}},{"Gene":"CD74","Gene synonym":["DHLAG"],"Ensembl":"ENSG00000019582","Gene description":"CD74 molecule","Uniprot":["P04233"],"Chromosome":"5","Position":"150400041-150412969","Protein class":["Cancer-related genes","CD markers","Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Chaperone"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"5258.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"11877.0","dendritic cells":"8770.5","Hofbauer cells":"5475.3","Langerhans cells":"27045.0","Macrophages":"6667.5","monocytes":"5775.7","Proximal enterocytes":"5559.6","Schwann cells":"10304.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"11041.2","intermediate monocyte":"15961.1","memory B-cell":"26889.3","myeloid DC":"23750.6","naive B-cell":"27930.3","non-classical monocyte":"8003.3","plasmacytoid DC":"16940.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"27930.3","dendritic cells":"23750.6","monocytes":"15961.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"912.4","lymphoma":"2863.9","Myeloma":"1700.9","skin cancer":"805.3"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Testis - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002506","HPA010592","CAB079994"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB002506":"AB_563630","CAB079994":null,"HPA010592":"AB_1078482"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.06e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.53e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"}},{"Gene":"CD79A","Gene synonym":["IGA","MB-1"],"Ensembl":"ENSG00000105369","Gene description":"CD79a molecule","Uniprot":["P11912"],"Chromosome":"19","Position":"41877279-41881372","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"152.3","lymphoid tissue":"545.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"27","RNA single cell type specific nTPM":{"B-cells":"1218.9","Plasma cells":"661.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"38","RNA blood cell specific nTPM":{"memory B-cell":"1273.8","naive B-cell":"1457.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"40","RNA blood lineage specific nTPM":{"B-cells":"1457.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"lymphoma":"740.6"},"RNA tissue cell type enrichment":["Breast - Plasma cells","Lung - Plasma cells","Skin - Plasma cells","Stomach - Plasma cells","Thyroid - Plasma cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000019","HPA056444"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000019":"AB_2244527","HPA056444":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.45e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"}},{"Gene":"CD79B","Gene synonym":["B29","IGB"],"Ensembl":"ENSG00000007312","Gene description":"CD79b molecule","Uniprot":["P40259"],"Chromosome":"17","Position":"63928740-63932336","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"266.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"497.2","monocytes":"88.7","Plasma cells":"125.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"1132.1","naive B-cell":"1505.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"1505.8"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"lymphoma":"593.0"},"RNA tissue cell type enrichment":["Prostate - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009178","CAB009751","HPA044107"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB009751":"AB_2275844","HPA009178":"AB_1078483","HPA044107":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.35e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"}},{"Gene":"CD80","Gene synonym":["B7-1","B7.1","CD28LG","CD28LG1"],"Ensembl":"ENSG00000121594","Gene description":"CD80 molecule","Uniprot":["P33681"],"Chromosome":"3","Position":"119524293-119559614","Protein class":["CD markers","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"3.0","lymphoid tissue":"6.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"9.2","Langerhans cells":"21.6","Macrophages":"6.9","monocytes":"9.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.4","T-reg":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"19.0"},"RNA tissue cell type enrichment":["Liver - Kupffer cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025368","HPA050092"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025368":null,"HPA050092":"AB_2681012"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"}},{"Gene":"CD81","Gene synonym":["TAPA-1","TAPA1","TSPAN28"],"Ensembl":"ENSG00000110651","Gene description":"CD81 molecule","Uniprot":["P60033"],"Chromosome":"11","Position":"2376177-2397397","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"2038.1","Endometrial stromal cells":"1090.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"148.9","naive B-cell":"137.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"148.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002507","HPA007234"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"400000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB002507":"AB_563639","HPA007234":"AB_1846333"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.56e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.21e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.86e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"}},{"Gene":"CD82","Gene synonym":["IA4","KAI1","R2","ST6","TSPAN27"],"Ensembl":"ENSG00000085117","Gene description":"CD82 molecule","Uniprot":["P27701"],"Chromosome":"11","Position":"44564427-44620358","Protein class":["Cancer-related genes","CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"200.5","Proximal enterocytes":"208.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"536.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"310.1","granulocytes":"536.4","T-cells":"173.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Stomach - Mitotic cells (Stomach)"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"white matter":"210.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002508","HPA028900","HPA061418"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB002508":"AB_563640","HPA028900":"AB_10603558","HPA061418":"AB_2684510"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"}},{"Gene":"CD83","Gene synonym":["BL11","HB15"],"Ensembl":"ENSG00000112149","Gene description":"CD83 molecule","Uniprot":["Q01151"],"Chromosome":"6","Position":"14117256-14136918","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"209.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"674.4","dendritic cells":"294.5","Langerhans cells":"1797.4","Macrophages":"514.4","monocytes":"512.5","Schwann cells":"435.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"90.7"},"RNA tissue cell type enrichment":["Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002509","HPA041454","HPA073595"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB002509":"AB_563641","HPA041454":"AB_2677489","HPA073595":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"}},{"Gene":"CD84","Gene synonym":["hCD84","mCD84","SLAMF5"],"Ensembl":"ENSG00000066294","Gene description":"CD84 molecule","Uniprot":["Q9UIB8"],"Chromosome":"1","Position":"160541095-160579516","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Autophagy","Cell adhesion","Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"24.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"131.0","Hofbauer cells":"91.4","Kupffer cells":"48.2","Langerhans cells":"48.1","Macrophages":"124.4","T-cells":"52.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"61","RNA cell line specific nTPM":{"Leukemia":"11.3","lymphoma":"9.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Liver - Kupffer cells","Skeletal muscle - Macrophages","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063316","HPA068020","HPA070502"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"35000000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA063316":null,"HPA068020":null,"HPA070502":"AB_2686274"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"}},{"Gene":"CD86","Gene synonym":["B7-2","B7.2","CD28LG2"],"Ensembl":"ENSG00000114013","Gene description":"CD86 molecule","Uniprot":["P42081"],"Chromosome":"3","Position":"122055362-122121139","Protein class":["CD markers","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"34.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"153.9","Kupffer cells":"66.3","Langerhans cells":"193.7","Macrophages":"137.3","Microglial cells":"76.6","monocytes":"280.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"classical monocyte":"79.9","intermediate monocyte":"79.0","memory B-cell":"41.0","myeloid DC":"78.8","naive B-cell":"28.5","non-classical monocyte":"85.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"B-cells":"41.0","dendritic cells":"78.8","monocytes":"85.2"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"lymphoma":"54.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004319","HPA026802"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"CAB004319":"AB_627200","HPA026802":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.83e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"}},{"Gene":"CD8A","Gene synonym":["CD8"],"Ensembl":"ENSG00000153563","Gene description":"CD8a molecule","Uniprot":["P01732"],"Chromosome":"2","Position":"86784610-86808396","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"lymphoid tissue":"369.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"T-cells":"231.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"MAIT T-cell":"234.4","memory CD8 T-cell":"523.0","naive CD8 T-cell":"476.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"T-cells":"523.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Leukemia":"6.0","lymphoma":"10.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Kidney - T-cells","Liver - T-cells","Lung - T-cells","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Stomach - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000012","HPA037756","CAB075722"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"490000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB000012":"AB_2075537","CAB075722":"AB_2665709","HPA037756":"AB_2675648"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.54e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.15e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"}},{"Gene":"CD8B","Gene synonym":["CD8B1"],"Ensembl":"ENSG00000172116","Gene description":"CD8b molecule","Uniprot":["P10966"],"Chromosome":"2","Position":"86815339-86861924","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"lymphoid tissue":"459.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"T-cells":"154.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"memory CD8 T-cell":"601.8","naive CD8 T-cell":"1053.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"25","RNA blood lineage specific nTPM":{"T-cells":"1053.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Leukemia":"8.8","Myeloma":"33.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Colon - T-cells","Kidney - T-cells","Liver - T-cells","Lung - T-cells","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Stomach - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004353","HPA029164"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB004353":"AB_627211","HPA029164":"AB_2672936"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.88e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.11e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"}},{"Gene":"CD8B2","Gene synonym":["CD8BP"],"Ensembl":"ENSG00000254126","Gene description":"CD8b2 molecule","Uniprot":["A6NJW9"],"Chromosome":"2","Position":"106487364-106544297","Protein class":["Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.7","lymphoid tissue":"7.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"T-cells":"1.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"memory CD8 T-cell":"18.8","naive CD8 T-cell":"30.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"T-cells":"30.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"breast cancer":"9.3","Myeloma":"19.5"},"RNA tissue cell type enrichment":["Skin - Fibroblast_2"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-3"}},{"Gene":"CD9","Gene synonym":["BA2","MIC3","MRP-1","P24","TSPAN29"],"Ensembl":"ENSG00000010278","Gene description":"CD9 molecule","Uniprot":["P21926"],"Chromosome":"12","Position":"6199715-6238271","Protein class":["Cancer-related genes","CD markers","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Fertilization"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"2735.4","Ionocytes":"2174.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"25","RNA blood cell specific nTPM":{"basophil":"1957.3","eosinophil":"1156.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"granulocytes":"1957.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002490"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002490":"AB_563643"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.93e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"}},{"Gene":"CD93","Gene synonym":["C1qR(P)","C1QR1","C1qRP","CDw93","dJ737E23.1","ECSM3","MXRA4"],"Ensembl":"ENSG00000125810","Gene description":"CD93 molecule","Uniprot":["Q9NPY3"],"Chromosome":"20","Position":"23079360-23086324","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"137.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"316.5","Endothelial cells":"281.4","Kupffer cells":"156.2","Macrophages":"116.9","monocytes":"92.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"classical monocyte":"25.8","intermediate monocyte":"16.8","myeloid DC":"9.1","neutrophil":"27.8","non-classical monocyte":"7.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"41","RNA blood lineage specific nTPM":{"dendritic cells":"9.1","granulocytes":"27.8","monocytes":"25.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"18.7","lymphoma":"10.5","ovarian cancer":"5.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Lung - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009300","HPA012368"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"550000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA009300":"AB_1846342","HPA012368":"AB_1846341"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.74e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"}},{"Gene":"CD96","Gene synonym":["TACTILE"],"Ensembl":"ENSG00000153283","Gene description":"CD96 molecule","Uniprot":["P40200"],"Chromosome":"3","Position":"111292719-111665750","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Craniosynostosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"61.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"NK-cells":"121.7","T-cells":"195.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"gdT-cell":"74.0","MAIT T-cell":"117.2","memory CD4 T-cell":"67.0","memory CD8 T-cell":"85.3","naive CD4 T-cell":"68.7","naive CD8 T-cell":"81.8","NK-cell":"79.5","T-reg":"47.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"NK-cells":"79.5","T-cells":"117.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"31.4","skin cancer":"16.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - T-cells","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066754"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"85000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066754":"AB_2685714"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.52e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.23e-5"}},{"Gene":"CD99","Gene synonym":["MIC2"],"Ensembl":"ENSG00000002586","Gene description":"CD99 molecule (Xg blood group)","Uniprot":["P14209"],"Chromosome":"X","Position":"2691187-2741309","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"1684.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Fibroblast_1","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000020","HPA035304"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"62000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB000020":"AB_2076419","HPA035304":"AB_10672861"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.87e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"}},{"Gene":"CD99L2","Gene synonym":["CD99B","MIC2L1"],"Ensembl":"ENSG00000102181","Gene description":"CD99 molecule like 2","Uniprot":["Q8TCZ2"],"Chromosome":"X","Position":"150766336-150898816","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"179.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"48.4","Inhibitory neurons":"55.9","Oligodendrocytes":"57.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038782","HPA038783","HPA061400"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA038782":"AB_10795139","HPA038783":"AB_10794734","HPA061400":"AB_2732660"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.96e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.74e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.74e-4"}},{"Gene":"CDAN1","Gene synonym":["CDA-I","CDAI"],"Ensembl":"ENSG00000140326","Gene description":"Codanin 1","Uniprot":["Q8IWY9"],"Chromosome":"15","Position":"42723544-42737128","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital dyserythropoietic anemia","Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039404","HPA040787"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA039404":"AB_10673530","HPA040787":"AB_2677137"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.07e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"}},{"Gene":"CDC14B","Gene synonym":["Cdc14B1","Cdc14B2","CDC14B3","hCDC14B"],"Ensembl":"ENSG00000081377","Gene description":"Cell division cycle 14B","Uniprot":["O60729"],"Chromosome":"9","Position":"96490241-96619843","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"27.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"83.8","Excitatory neurons":"82.2","Inhibitory neurons":"107.6","Oligodendrocyte precursor cells":"150.2","Oligodendrocytes":"258.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"10.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"10.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skin - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064747"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA064747":"AB_2732719"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.97e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.82e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"}},{"Gene":"CDC14C","Gene synonym":["CDC14B2","CDC14Bretro","CDC14CP","MGC26484"],"Ensembl":"ENSG00000218305","Gene description":"Cell division cycle 14C","Uniprot":["A4D256"],"Chromosome":"7","Position":"48919765-48927454","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"2.0","testis":"7.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"8.8","Late spermatids":"8.0","Spermatocytes":"15.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064747"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA064747":"AB_2732719"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CDC37","Gene synonym":["P50CDC37"],"Ensembl":"ENSG00000105401","Gene description":"Cell division cycle 37, HSP90 cochaperone","Uniprot":["Q16543"],"Chromosome":"19","Position":"10391133-10420121","Protein class":["Cancer-related genes","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003928","CAB004214"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"610000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004214":"AB_627232","HPA003928":"AB_1846373"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"}},{"Gene":"CDC42","Gene synonym":["CDC42Hs","G25K"],"Ensembl":"ENSG00000070831","Gene description":"Cell division cycle 42","Uniprot":["P60953"],"Chromosome":"1","Position":"22025511-22101360","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004360","HPA069590"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Microtubules","Cytokinetic bridge"],"Subcellular additional location":null,"Antibody RRID":{"CAB004360":"AB_627233","HPA069590":"AB_2732138"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.28e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"}},{"Gene":"CDCA5","Gene synonym":[],"Ensembl":"ENSG00000146670","Gene description":"Cell division cycle associated 5","Uniprot":["Q96FF9"],"Chromosome":"11","Position":"65066300-65084164","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"53.4","lymphoid tissue":"27.6","testis":"37.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"60.1","Erythroid cells":"30.3","Extravillous trophoblasts":"39.1","Late spermatids":"117.5","Spermatocytes":"47.8","Spermatogonia":"33.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"NK-cell":"2.8","T-reg":"2.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"NK-cells":"2.8","T-cells":"2.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Mitotic cells (Colon)","Heart muscle - Mitotic cells (Heart)","Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Testis - Early spermatids","Thyroid - Mitotic cells (Thyroid)"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"white matter":"1.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023691","HPA076007"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA023691":"AB_1846392","HPA076007":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.67e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.21e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.72e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"}},{"Gene":"CDCP1","Gene synonym":["CD318","SIMA135"],"Ensembl":"ENSG00000163814","Gene description":"CUB domain containing protein 1","Uniprot":["Q9H5V8"],"Chromosome":"3","Position":"45082277-45146422","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"37.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"113.1","Basal respiratory cells":"89.2","Exocrine glandular cells":"91.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"2.3","NK-cell":"4.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Heart muscle - Macrophages","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010978","HPA010979","CAB025637"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025637":null,"HPA010978":"AB_1846403","HPA010979":"AB_1846401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.41e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.48e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"CDCP2","Gene synonym":[],"Ensembl":"ENSG00000157211","Gene description":"CUB domain containing protein 2","Uniprot":["Q5VXM1"],"Chromosome":"1","Position":"54132968-54153770","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031143"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031143":"AB_10611819"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"}},{"Gene":"CDH1","Gene synonym":["CD324","UVO","uvomorulin"],"Ensembl":"ENSG00000039068","Gene description":"Cadherin 1","Uniprot":["P12830"],"Chromosome":"16","Position":"68737292-68835537","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"197.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"258.8","Distal enterocytes":"274.4","Glandular and luminal cells":"317.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"myeloid DC":"1.7","plasmacytoid DC":"4.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"4.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enterocytes","Liver - Hepatocytes","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000087","HPA004812","CAB028364","CAB072855","CAB072856","CAB072857"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"78000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB000087":"AB_2533003","CAB028364":"AB_2076812","CAB072855":"AB_2665698","CAB072856":"AB_2665699","CAB072857":"AB_2665700","HPA004812":"AB_1078369"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.06e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"}},{"Gene":"CDH10","Gene synonym":[],"Ensembl":"ENSG00000040731","Gene description":"Cadherin 10","Uniprot":["Q9Y6N8"],"Chromosome":"5","Position":"24487100-24644978","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"13.0","prostate":"4.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Astrocytes":"164.2","Excitatory neurons":"417.5","Inhibitory neurons":"210.9","Oligodendrocyte precursor cells":"467.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"5.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"7.4","testis cancer":"11.7"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010651","HPA012085"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA010651":"AB_1078370","HPA012085":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"}},{"Gene":"CDH11","Gene synonym":["CAD11","OB"],"Ensembl":"ENSG00000140937","Gene description":"Cadherin 11","Uniprot":["P55287"],"Chromosome":"16","Position":"64943753-65126112","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"178.2","placenta":"122.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"90.1","Endometrial stromal cells":"115.4","Excitatory neurons":"120.0","Microglial cells":"141.4","Oligodendrocyte precursor cells":"151.6","Oligodendrocytes":"100.4","Theca cells":"176.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"104.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Kidney - Fibroblasts","Lung - Fibroblast_1","Testis - Peritubular cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013072"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4800000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013072":"AB_2533068"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-3"}},{"Gene":"CDH12","Gene synonym":["Br-cadherin","CDHB"],"Ensembl":"ENSG00000154162","Gene description":"Cadherin 12","Uniprot":["P55289"],"Chromosome":"5","Position":"21750673-22853344","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.6","retina":"11.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Excitatory neurons":"846.0","Inhibitory neurons":"865.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"6.6","cerebral cortex":"3.8","hippocampal formation":"2.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"3.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029325"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029325":"AB_2672998"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"}},{"Gene":"CDH13","Gene synonym":["CDHH"],"Ensembl":"ENSG00000140945","Gene description":"Cadherin 13","Uniprot":["P55290"],"Chromosome":"16","Position":"82626965-83800640","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"57.1","skeletal muscle":"68.6","tongue":"57.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"323.4","Inhibitory neurons":"844.1","Oligodendrocyte precursor cells":"321.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"4.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.2","monocytes":"4.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"103.5"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Lung - Fibroblast_1","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001380","CAB025863"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB025863":null,"HPA001380":"AB_1078371"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"}},{"Gene":"CDH15","Gene synonym":["CDH14","CDH3"],"Ensembl":"ENSG00000129910","Gene description":"Cadherin 15","Uniprot":["P55291"],"Chromosome":"16","Position":"89171748-89195492","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"24.4","skeletal muscle":"57.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Skeletal myocytes":"67.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"15","RNA brain regional specific nTPM":{"cerebellum":"24.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"24","RNA cell line specific nTPM":{"Sarcoma":"32.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"cerebellum":"15.7"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"17","RNA pig brain regional specific nTPM":{"cerebellum":"18.7"},"Antibody":["HPA009139","HPA070961"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"870000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA009139":"AB_1078372","HPA070961":"AB_2686328"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"}},{"Gene":"CDH16","Gene synonym":[],"Ensembl":"ENSG00000166589","Gene description":"Cadherin 16","Uniprot":["O75309"],"Chromosome":"16","Position":"66908122-66918917","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"kidney":"250.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Collecting duct cells":"478.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"renal cancer":"96.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Bile duct cancer":"15.6","Kidney cancer":"15.8","ovarian cancer":"4.8","Uterine cancer":"9.0"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013526","HPA036260"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013526":null,"HPA036260":"AB_2675027"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.02e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"}},{"Gene":"CDH17","Gene synonym":["cadherin","HPT-1"],"Ensembl":"ENSG00000079112","Gene description":"Cadherin 17","Uniprot":["Q12864"],"Chromosome":"8","Position":"94127162-94217303","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"intestine":"314.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"146","RNA single cell type specific nTPM":{"Distal enterocytes":"449.7","Enteroendocrine cells":"171.3","Intestinal goblet cells":"198.2","Paneth cells":"288.3","Proximal enterocytes":"316.8","Undifferentiated cells":"136.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"colorectal cancer":"156.4","stomach cancer":"54.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"16.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"granulocytes":"16.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bile duct cancer":"60.1","colorectal cancer":"155.8","Gastric cancer":"69.6","pancreatic cancer":"53.3"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Pancreas - Ductal cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023614","HPA023616","CAB025143","HPA026556"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7500000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB025143":null,"HPA023614":"AB_1845896","HPA023616":"AB_1845895","HPA026556":"AB_1845897"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"}},{"Gene":"CDH18","Gene synonym":["CDH14","EY-CADHERIN"],"Ensembl":"ENSG00000145526","Gene description":"Cadherin 18","Uniprot":["Q13634"],"Chromosome":"5","Position":"19471296-20575873","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"35.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"911.2","Inhibitory neurons":"680.2","Oligodendrocyte precursor cells":"237.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"0.7"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"35.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014416"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014416":"AB_2668996"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"}},{"Gene":"CDH19","Gene synonym":["CDH7"],"Ensembl":"ENSG00000071991","Gene description":"Cadherin 19","Uniprot":["Q9H159"],"Chromosome":"18","Position":"66501083-66604138","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.4","heart muscle":"37.1","intestine":"19.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"181.8","Schwann cells":"682.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"21","RNA cancer specific FPKM":{"melanoma":"16.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Sarcoma":"4.8","skin cancer":"13.8"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056332"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056332":"AB_2683102"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-5"}},{"Gene":"CDH2","Gene synonym":["CD325","CDHN","NCAD"],"Ensembl":"ENSG00000170558","Gene description":"Cadherin 2","Uniprot":["P19022"],"Chromosome":"18","Position":"27932879-28177946","Protein class":["CD markers","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"196.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"211.0","Cardiomyocytes":"387.3","Excitatory neurons":"306.3","Granulosa cells":"302.3","Inhibitory neurons":"193.1","Oligodendrocyte precursor cells":"256.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"39.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"1.7","neutrophil":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"1.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000141","CAB018580","HPA058574","CAB078686","CAB080169"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"CAB000141":null,"CAB018580":"AB_626778","CAB078686":"AB_2665849","CAB080169":null,"HPA058574":"AB_2683760"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"}},{"Gene":"CDH20","Gene synonym":["Cdh7","CDH7L3"],"Ensembl":"ENSG00000101542","Gene description":"Cadherin 20","Uniprot":["Q9HBT6"],"Chromosome":"18","Position":"61333430-61555779","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"33.7","retina":"11.0","tongue":"24.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"1225.1","Oligodendrocyte precursor cells":"711.0","Oligodendrocytes":"973.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"glioma":"6.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"23","RNA blood cell specific nTPM":{"basophil":"2.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"24","RNA blood lineage specific nTPM":{"granulocytes":"2.3"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"}},{"Gene":"CDH22","Gene synonym":["C20orf25","dJ998H6.1"],"Ensembl":"ENSG00000149654","Gene description":"Cadherin 22","Uniprot":["Q9UJ99"],"Chromosome":"20","Position":"46173739-46308498","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"19.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"47.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"10.7","basal ganglia":"5.0","cerebellum":"19.5","cerebral cortex":"15.2","hippocampal formation":"7.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Uterine cancer":"1.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012164","HPA012715"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012164":"AB_1845902","HPA012715":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"}},{"Gene":"CDH23","Gene synonym":["CDHR23","DFNB12","USH1D"],"Ensembl":"ENSG00000107736","Gene description":"Cadherin related 23","Uniprot":["Q9H251"],"Chromosome":"10","Position":"71396920-71815947","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Hearing","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.6","ovary":"35.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"50.2","Late spermatids":"83.8","Microglial cells":"32.8","monocytes":"57.7","Muller glia cells":"82.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"26.8","non-classical monocyte":"38.1","plasmacytoid DC":"9.5"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"monocytes":"38.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"10.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017232"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"950000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017232":"AB_1845903"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.40e-4"}},{"Gene":"CDH24","Gene synonym":["CDH11L"],"Ensembl":"ENSG00000139880","Gene description":"Cadherin 24","Uniprot":["Q86UP0"],"Chromosome":"14","Position":"23047062-23057538","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"10.9","Astrocytes":"8.9","Endothelial cells":"9.3","Horizontal cells":"35.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074551"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA074551":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.15e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"}},{"Gene":"CDH26","Gene synonym":["VR20"],"Ensembl":"ENSG00000124215","Gene description":"Cadherin 26","Uniprot":["Q8IXH8"],"Chromosome":"20","Position":"59958423-60034011","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"8.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"17.4","Club cells":"17.8","Ionocytes":"16.8","Oligodendrocytes":"14.1","Prostatic glandular cells":"31.2","Respiratory ciliated cells":"24.7","Syncytiotrophoblasts":"14.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"cervical cancer":"1.5","head and neck cancer":"0.9","lung cancer":"2.3","prostate cancer":"3.6","urothelial cancer":"3.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"4.6","prostate cancer":"8.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015722","HPA047578"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Microtubules"],"Antibody RRID":{"HPA015722":"AB_2077659","HPA047578":"AB_2680091"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.62e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.75e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"CDH3","Gene synonym":["CDHP","PCAD"],"Ensembl":"ENSG00000062038","Gene description":"Cadherin 3","Uniprot":["P22223"],"Chromosome":"16","Position":"68636189-68727468","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Ectodermal dysplasia","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"47.1","ovary":"32.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"59.5","Basal respiratory cells":"156.2","Basal squamous epithelial cells":"69.0","Exocrine glandular cells":"49.7","Granulosa cells":"74.8","Ionocytes":"50.5","Melanocytes":"92.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"169.7"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001767","CAB002487"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"510000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"CAB002487":"AB_563446","HPA001767":"AB_1078376"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.53e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.43e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"}},{"Gene":"CDH4","Gene synonym":[],"Ensembl":"ENSG00000179242","Gene description":"Cadherin 4","Uniprot":["P55283"],"Chromosome":"20","Position":"61252261-61940617","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"11.0","lymphoid tissue":"3.7","ovary":"6.3","skeletal muscle":"3.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"152.1","Excitatory neurons":"53.7","Inhibitory neurons":"68.2","Oligodendrocyte precursor cells":"103.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"6.9","renal cancer":"3.4","thyroid cancer":"2.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"9.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015613"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA015613":"AB_2732414"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"}},{"Gene":"CDH5","Gene synonym":["7B4","CD144"],"Ensembl":"ENSG00000179776","Gene description":"Cadherin 5","Uniprot":["P33151"],"Chromosome":"16","Position":"66366622-66404784","Protein class":["Cancer-related genes","CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"235.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"296.8","Endothelial cells":"212.8","Extravillous trophoblasts":"50.9","Late spermatids":"86.2","Syncytiotrophoblasts":"121.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"13.1","Rhabdoid":"12.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Lung - Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Stomach - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB028366","HPA075875"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Nuclear membrane"],"Antibody RRID":{"CAB028366":"AB_2276033","HPA075875":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"}},{"Gene":"CDH6","Gene synonym":[],"Ensembl":"ENSG00000113361","Gene description":"Cadherin 6","Uniprot":["P55285"],"Chromosome":"5","Position":"31193686-31329146","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"14.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"46.2","Excitatory neurons":"65.9","Microglial cells":"38.3","Oligodendrocyte precursor cells":"58.2","Proximal tubular cells":"185.3","Smooth muscle cells":"54.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"ovarian cancer":"15.0","renal cancer":"28.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"44.1","ovarian cancer":"81.9"},"RNA tissue cell type enrichment":["Prostate - Endothelial cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007047","HPA007403","HPA007456","CAB025274"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9600000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB025274":null,"HPA007047":"AB_1078374","HPA007403":null,"HPA007456":"AB_1078373"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"}},{"Gene":"CDH7","Gene synonym":[],"Ensembl":"ENSG00000081138","Gene description":"Cadherin 7","Uniprot":["Q9ULB5"],"Chromosome":"18","Position":"65750252-65890337","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"16.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"44.9","Horizontal cells":"58.3","Inhibitory neurons":"109.1","Muller glia cells":"34.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"1.0","lung cancer":"3.1","Neuroblastoma":"2.1","prostate cancer":"3.2","Rhabdoid":"1.6","Sarcoma":"3.5","thyroid cancer":"2.9"},"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061419"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA061419":"AB_2684511"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"}},{"Gene":"CDH8","Gene synonym":[],"Ensembl":"ENSG00000150394","Gene description":"Cadherin 8","Uniprot":["P55286"],"Chromosome":"16","Position":"61647242-62037035","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"22.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Excitatory neurons":"217.6","Inhibitory neurons":"229.8","Oligodendrocytes":"137.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"10.3","Rhabdoid":"13.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014908","HPA076441"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"870000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014908":"AB_1845908","HPA076441":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"CDH9","Gene synonym":[],"Ensembl":"ENSG00000113100","Gene description":"Cadherin 9","Uniprot":["Q9ULB4"],"Chromosome":"5","Position":"26880597-27121150","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.8","kidney":"5.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"33","RNA single cell type specific nTPM":{"Excitatory neurons":"302.4","Inhibitory neurons":"448.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"amygdala":"6.8","basal ganglia":"4.3","cerebral cortex":"6.4","hippocampal formation":"5.8"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"4.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"2.3","granulocytes":"4.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007167"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA007167":"AB_1078489"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-4"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CDHR1","Gene synonym":["CORD15","KIAA1775","PCDH21","RP65"],"Ensembl":"ENSG00000148600","Gene description":"Cadherin related family member 1","Uniprot":["Q96JP9"],"Chromosome":"10","Position":"84194537-84219621","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Receptor"],"Disease involvement":["Cone-rod dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"313.8","skin 1":"214.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"365.3","Rod photoreceptor cells":"218.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"13.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"NK-cell":"7.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"NK-cells":"7.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"18.0"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Colon - Colon enterocytes","Liver - NK-cells (Liver)","Skin - Keratinocyte (other)","Stomach - Fibroblasts","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"21","RNA mouse brain regional specific nTPM":{"olfactory bulb":"333.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010795","HPA036819"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA010795":null,"HPA036819":"AB_10671750"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"}},{"Gene":"CDHR2","Gene synonym":["FLJ20124","FLJ20383","PC-LKC","PCDH24","PCLKC"],"Ensembl":"ENSG00000074276","Gene description":"Cadherin related family member 2","Uniprot":["Q9BYE9"],"Chromosome":"5","Position":"176542511-176595974","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"intestine":"275.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"706.3","Proximal enterocytes":"500.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"colorectal cancer":"9.1","liver cancer":"5.7","pancreatic cancer":"11.7","renal cancer":"8.6","stomach cancer":"9.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"colorectal cancer":"4.6","Gastric cancer":"6.5","liver cancer":"4.1","pancreatic cancer":"9.2"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Lung - Respiratory ciliated cells","Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"hypothalamus":"2.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012569","HPA017053"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8800000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012569":"AB_1845298","HPA017053":"AB_1845297"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"}},{"Gene":"CDHR3","Gene synonym":["CDH28","FLJ23834","FLJ44366"],"Ensembl":"ENSG00000128536","Gene description":"Cadherin related family member 3","Uniprot":["Q6ZTQ4"],"Chromosome":"7","Position":"105876796-106036432","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Asthma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"46.4","fallopian tube":"108.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"165.4","Endometrial ciliated cells":"139.7","Enteroendocrine cells":"92.1","Excitatory neurons":"69.1","Inhibitory neurons":"62.5","Respiratory ciliated cells":"291.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"2.0","naive B-cell":"2.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"4.9"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Lung - Respiratory ciliated cells","Skeletal muscle - Fibroblasts","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"11.8"},"Antibody":["HPA011218"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011218":"AB_1078886"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"}},{"Gene":"CDHR4","Gene synonym":["CDH29","VLLR9392"],"Ensembl":"ENSG00000187492","Gene description":"Cadherin related family member 4","Uniprot":["A6H8M9"],"Chromosome":"3","Position":"49790732-49799873","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"fallopian tube":"59.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"71.7","Respiratory ciliated cells":"129.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"endometrial cancer":"6.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Lung - Respiratory ciliated cells","Testis - Early spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"1.2"},"Antibody":["HPA076277"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA076277":"AB_2732306"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"}},{"Gene":"CDHR5","Gene synonym":["FLJ20219","MU-PCDH","MUCDHL","MUPCDH"],"Ensembl":"ENSG00000099834","Gene description":"Cadherin related family member 5","Uniprot":["Q9HBB8"],"Chromosome":"11","Position":"616577-626078","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"296.8","liver":"129.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"2316.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"61.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"3.2"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009081","HPA009173","CAB025004"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025004":null,"HPA009081":"AB_1079428","HPA009173":"AB_1079429"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"}},{"Gene":"CDIP1","Gene synonym":["C16orf5","CDIP","LITAFL"],"Ensembl":"ENSG00000089486","Gene description":"Cell death inducing p53 target 1","Uniprot":["Q9H305"],"Chromosome":"16","Position":"4510669-4538828","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049352"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA049352":"AB_2680724"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.14e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"}},{"Gene":"CDIPT","Gene synonym":["PIS","PIS1"],"Ensembl":"ENSG00000103502","Gene description":"CDP-diacylglycerol--inositol 3-phosphatidyltransferase","Uniprot":["O14735"],"Chromosome":"16","Position":"29858357-29863414","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056597"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm","Nuclear membrane","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA056597":"AB_2683182"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.40e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"}},{"Gene":"CDK10","Gene synonym":["PISSLRE"],"Ensembl":"ENSG00000185324","Gene description":"Cyclin dependent kinase 10","Uniprot":["Q15131"],"Chromosome":"16","Position":"89680737-89696354","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007451","HPA059634","HPA067060"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Midbody","Midbody ring"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Midbody","Midbody ring"],"Subcellular additional location":null,"Antibody RRID":{"HPA007451":"AB_2732400","HPA059634":"AB_2684090","HPA067060":"AB_2685772"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.69e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.63e-4"}},{"Gene":"CDK13","Gene synonym":["CDC2L","CDC2L5","CHED","KIAA1791"],"Ensembl":"ENSG00000065883","Gene description":"Cyclin dependent kinase 13","Uniprot":["Q14004"],"Chromosome":"7","Position":"39950121-40099580","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","mRNA processing","mRNA splicing"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059241"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA059241":"AB_2683956"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"}},{"Gene":"CDK2","Gene synonym":[],"Ensembl":"ENSG00000123374","Gene description":"Cyclin dependent kinase 2","Uniprot":["P24941"],"Chromosome":"12","Position":"55966781-55972789","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","DNA damage","DNA repair","Meiosis","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"92.5","Extravillous trophoblasts":"79.2","Langerhans cells":"51.9","Melanocytes":"121.9","Syncytiotrophoblasts":"192.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"88.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"245.0"},"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013115","HPA066915"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"CAB013115":"AB_2536375","HPA066915":"AB_2685748"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.94e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.61e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.46e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"}},{"Gene":"CDK5RAP1","Gene synonym":["C20orf34","C42","CGI-05","HSPC167"],"Ensembl":"ENSG00000101391","Gene description":"CDK5 regulatory subunit associated protein 1","Uniprot":["Q96SZ6"],"Chromosome":"20","Position":"33358839-33401561","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051329","HPA055429"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA051329":null,"HPA055429":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.07e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"CDKAL1","Gene synonym":["FLJ20342"],"Ensembl":"ENSG00000145996","Gene description":"CDK5 regulatory subunit associated protein 1 like 1","Uniprot":["Q5VV42"],"Chromosome":"6","Position":"20534457-21232404","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["tRNA processing"],"Molecular function":["Transferase"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"129.1","Excitatory neurons":"157.1","Inhibitory neurons":"130.8","Microglial cells":"193.4","Oligodendrocyte precursor cells":"190.1","Oligodendrocytes":"241.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"}},{"Gene":"CDKN3","Gene synonym":["CDI1","KAP"],"Ensembl":"ENSG00000100526","Gene description":"Cyclin dependent kinase inhibitor 3","Uniprot":["Q16667"],"Chromosome":"14","Position":"54396849-54420218","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"207.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"2499.5","Late spermatids":"1090.3","Spermatocytes":"517.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"18.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"NK-cells":"6.4","T-cells":"18.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005285","HPA039311","HPA058874"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005285":"AB_2078884","HPA039311":null,"HPA058874":"AB_2683842"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.52e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.46e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"}},{"Gene":"CDON","Gene synonym":["CDO","CDON1","ORCAM"],"Ensembl":"ENSG00000064309","Gene description":"Cell adhesion associated, oncogene regulated","Uniprot":["Q4KMG0"],"Chromosome":"11","Position":"125955796-126063335","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Holoprosencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"57.4","Inhibitory neurons":"48.5","Muller glia cells":"34.4","Thymic epithelial cells":"50.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"23.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"23.8"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Keratinocyte (other)","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012422","HPA017377"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB012422":"AB_2260246","HPA017377":"AB_1846453"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.78e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-4"}},{"Gene":"CDRT1","Gene synonym":["FBXW10B","FBXW10P1","HREP","SM25H2"],"Ensembl":"ENSG00000241322","Gene description":"CMT1A duplicated region transcript 1","Uniprot":["O95170"],"Chromosome":"17","Position":"15565483-15619704","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"8.5","testis":"12.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"13.6","Early spermatids":"26.4","Ionocytes":"26.2","Late spermatids":"13.2","Respiratory ciliated cells":"23.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013332","HPA047457"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA013332":"AB_1848471","HPA047457":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"}},{"Gene":"CDRT15L2","Gene synonym":[],"Ensembl":"ENSG00000214819","Gene description":"CMT1A duplicated region transcript 15 like 2","Uniprot":["A8MXV6"],"Chromosome":"17","Position":"20579724-20580911","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"testis":"15.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"132.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"1.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CDS1","Gene synonym":[],"Ensembl":"ENSG00000163624","Gene description":"CDP-diacylglycerol synthase 1","Uniprot":["Q92903"],"Chromosome":"4","Position":"84583127-84651334","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"139.7","Respiratory ciliated cells":"208.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Pancreas - Ductal cells","Stomach - Gastric mucous cells","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036187","HPA064546"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036187":"AB_10601797","HPA064546":"AB_2732714"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.22e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"}},{"Gene":"CDS2","Gene synonym":[],"Ensembl":"ENSG00000101290","Gene description":"CDP-diacylglycerol synthase 2","Uniprot":["O95674"],"Chromosome":"20","Position":"5126879-5197887","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019698"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA019698":"AB_1846464"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.53e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"}},{"Gene":"CEACAM1","Gene synonym":["BGP","BGP1","CD66a"],"Ensembl":"ENSG00000079385","Gene description":"CEA cell adhesion molecule 1","Uniprot":["P13688"],"Chromosome":"19","Position":"42507304-42561234","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"246.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal enterocytes":"614.7","Paneth cells":"244.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"43.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"eosinophil":"43.6","neutrophil":"26.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"43.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Colon - Colon enterocytes","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002146","HPA011041"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002146":"AB_563614","HPA011041":"AB_1078481"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.32e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"}},{"Gene":"CEACAM19","Gene synonym":["CEAL1"],"Ensembl":"ENSG00000186567","Gene description":"CEA cell adhesion molecule 19","Uniprot":["Q7Z692"],"Chromosome":"19","Position":"44662278-44684359","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"7.8","Suprabasal keratinocytes":"11.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Lung - Endothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"1.1"},"Antibody":["HPA014462","HPA052865"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nucleoli","Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA014462":"AB_2669006","HPA052865":"AB_2681976"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"}},{"Gene":"CEACAM20","Gene synonym":["UNQ9366"],"Ensembl":"ENSG00000273777","Gene description":"CEA cell adhesion molecule 20","Uniprot":["Q6UY09"],"Chromosome":"19","Position":"44501677-44529788","Protein class":["Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"37.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Proximal enterocytes":"37.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"prostate cancer":"5.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"prostate cancer":"24.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"CEACAM21","Gene synonym":["FLJ13540","R29124_1"],"Ensembl":"ENSG00000007129","Gene description":"CEA cell adhesion molecule 21","Uniprot":["Q3KPI0"],"Chromosome":"19","Position":"41549518-41586844","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"17.5","lymphoid tissue":"10.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Granulosa cells":"140.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"4.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"2.9","Myeloma":"5.5"},"RNA tissue cell type enrichment":["Prostate - T-cells","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043411"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043411":"AB_10794886"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.89e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"CEACAM3","Gene synonym":["CD66d","CGM1"],"Ensembl":"ENSG00000170956","Gene description":"CEA cell adhesion molecule 3","Uniprot":["P40198"],"Chromosome":"19","Position":"41796587-41811554","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"bone marrow":"44.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Paneth cells":"48.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"289.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"289.3"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Lung - NK-cells (Lung)","Stomach - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011041"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011041":"AB_1078481"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"}},{"Gene":"CEACAM4","Gene synonym":["CGM7"],"Ensembl":"ENSG00000105352","Gene description":"CEA cell adhesion molecule 4","Uniprot":["O75871"],"Chromosome":"19","Position":"41618971-41627074","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"21.3","lymphoid tissue":"32.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Hofbauer cells":"9.5","Kupffer cells":"30.4","Macrophages":"22.3","monocytes":"16.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"122.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"122.7"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"1.8"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Kidney - Macrophages","Liver - Neutrophils","Lung - Neutrophil_2","Pancreas - Macrophages","Prostate - Macrophages","Skin - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-1"}},{"Gene":"CEACAM7","Gene synonym":["CEA","CGM2"],"Ensembl":"ENSG00000007306","Gene description":"CEA cell adhesion molecule 7","Uniprot":["Q14002"],"Chromosome":"19","Position":"41673303-41706976","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"intestine":"651.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Distal enterocytes":"1219.2","Paneth cells":"333.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"66.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bladder cancer":"2.2","cervical cancer":"4.1","colorectal cancer":"2.6"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069621","HPA073910"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA069621":"AB_2686162","HPA073910":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"}},{"Gene":"CEACAM8","Gene synonym":["CD66b","CGM6"],"Ensembl":"ENSG00000124469","Gene description":"CEA cell adhesion molecule 8","Uniprot":["P31997"],"Chromosome":"19","Position":"42580243-42595055","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"36","RNA tissue specific nTPM":{"bone marrow":"217.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Paneth cells":"4.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"1.6","non-classical monocyte":"1.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"1.6","monocytes":"1.2"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Erythroid cells","Lung - Neutrophil_1"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033676"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9200000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033676":"AB_1125678"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"CEBPZOS","Gene synonym":["CEBPZ-AS1"],"Ensembl":"ENSG00000218739","Gene description":"CEBPZ opposite strand","Uniprot":["A8MTT3"],"Chromosome":"2","Position":"37196488-37216193","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053866"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053866":"AB_2682283"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.46e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"}},{"Gene":"CELA2B","Gene synonym":["ELA2B","RP11-265F14.2"],"Ensembl":"ENSG00000215704","Gene description":"Chymotrypsin like elastase 2B","Uniprot":["P08218"],"Chromosome":"1","Position":"15465909-15491395","Protein class":["Enzymes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"1672","RNA tissue specific nTPM":{"pancreas":"20446.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Respiratory ciliated cells":"1892.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"574","RNA cancer specific FPKM":{"pancreatic cancer":"69.9"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"2.0","cerebral cortex":"3.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Exocrine glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 20: Airway & Pancreas - Proteolysis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"}},{"Gene":"CELSR1","Gene synonym":["ADGRC1","CDHF9","FMI2","HFMI2","ME2"],"Ensembl":"ENSG00000075275","Gene description":"Cadherin EGF LAG seven-pass G-type receptor 1","Uniprot":["Q9NYQ6"],"Chromosome":"22","Position":"46360834-46537620","Protein class":["Disease related genes","G-protein coupled receptors","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"31.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"29.4","Basal respiratory cells":"29.0","Club cells":"31.6","Endometrial ciliated cells":"31.1","Glandular and luminal cells":"35.8","Ionocytes":"25.8","Respiratory ciliated cells":"75.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory B-cell":"2.2","naive B-cell":"1.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"2.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate basal glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052976","HPA060521"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA052976":"AB_2682004","HPA060521":"AB_2684303"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"CELSR2","Gene synonym":["ADGRC2","CDHF10","EGFL2","Flamingo1","KIAA0279","MEGF3"],"Ensembl":"ENSG00000143126","Gene description":"Cadherin EGF LAG seven-pass G-type receptor 2","Uniprot":["Q9HCU4"],"Chromosome":"1","Position":"109249539-109275751","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"50.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"51.3","Oligodendrocytes":"45.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"amygdala":"13.3","basal ganglia":"21.6","cerebral cortex":"44.6","hippocampal formation":"50.8","white matter":"26.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013952"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA013952":"AB_1846518"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"}},{"Gene":"CELSR3","Gene synonym":["ADGRC3","CDHF11","EGFL1","FMI1","HFMI1","MEGF2"],"Ensembl":"ENSG00000008300","Gene description":"Cadherin EGF LAG seven-pass G-type receptor 3","Uniprot":["Q9NYQ7"],"Chromosome":"3","Position":"48636463-48662886","Protein class":["G-protein coupled receptors","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"7.3","pituitary gland":"7.3","retina":"3.8","testis":"2.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"14.3","Cone photoreceptor cells":"22.4","Excitatory neurons":"10.0","Horizontal cells":"21.1","Inhibitory neurons":"10.5","Rod photoreceptor cells":"11.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062866"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062866":"AB_2684886"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"}},{"Gene":"CEMIP2","Gene synonym":["TMEM2"],"Ensembl":"ENSG00000135048","Gene description":"Cell migration inducing hyaluronidase 2","Uniprot":["Q9UHN6"],"Chromosome":"9","Position":"71683366-71816690","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis"],"Molecular function":["Developmental protein","Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"92.5","placenta":"79.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"496.0","T-cells":"177.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017080","HPA044889"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA017080":null,"HPA044889":"AB_10962641"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.31e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"}},{"Gene":"CEND1","Gene synonym":["BM88","FLJ90066"],"Ensembl":"ENSG00000184524","Gene description":"Cell cycle exit and neuronal differentiation 1","Uniprot":["Q8N111"],"Chromosome":"11","Position":"787115-790113","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"234.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"83.2","Excitatory neurons":"42.4","Horizontal cells":"96.8","Inhibitory neurons":"44.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"glioma":"24.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"23.4","Rhabdoid":"26.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Ascending Loop of Henle cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042527"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA042527":"AB_2678038"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.38e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"}},{"Gene":"CENPL","Gene synonym":["C1orf155","dJ383J4.3","FLJ31044"],"Ensembl":"ENSG00000120334","Gene description":"Centromere protein L","Uniprot":["Q8N0S6"],"Chromosome":"1","Position":"173799550-173824720","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"9.6","testis":"9.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"30.6","Spermatocytes":"42.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044520"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044520":"AB_10794500"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.51e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.60e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"}},{"Gene":"CENPW","Gene synonym":["C6orf173","CUG2"],"Ensembl":"ENSG00000203760","Gene description":"Centromere protein W","Uniprot":["Q5EE01"],"Chromosome":"6","Position":"126340115-126348875","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"50.6","testis":"39.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"442.2","Extravillous trophoblasts":"174.2","Spermatocytes":"146.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Mitotic cells (Skin)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067285"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA067285":"AB_2685818"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.21e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"}},{"Gene":"CEP170","Gene synonym":["FAM68A","KAB","KIAA0470"],"Ensembl":"ENSG00000143702","Gene description":"Centrosomal protein 170","Uniprot":["Q5SW79"],"Chromosome":"1","Position":"243124428-243255348","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"52.6","brain":"66.3","testis":"89.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Late spermatids":"2504.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042151","HPA045597","HPA045787"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA042151":"AB_2677876","HPA045597":"AB_2732522","HPA045787":"AB_2679453"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.30e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"}},{"Gene":"CEP20","Gene synonym":["C16orf63","DKFZp686N1651","FLJ31153","FOPNL","FOR20","PHSECRG2"],"Ensembl":"ENSG00000133393","Gene description":"Centrosomal protein 20","Uniprot":["Q96NB1"],"Chromosome":"16","Position":"15865719-15888625","Protein class":["Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"223.5","Late spermatids":"575.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040599"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA040599":"AB_10794036"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-3"}},{"Gene":"CEP41","Gene synonym":["DKFZp762H1311","FLJ22445","JBTS15","TSGA14"],"Ensembl":"ENSG00000106477","Gene description":"Centrosomal protein 41","Uniprot":["Q9BYV8"],"Chromosome":"7","Position":"130393771-130442433","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Autism","Autism spectrum disorder","Ciliopathy","Joubert syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"47.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"566.8","Late spermatids":"198.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024090"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024090":"AB_10966276"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.54e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"}},{"Gene":"CEP68","Gene synonym":["KIAA0582"],"Ensembl":"ENSG00000011523","Gene description":"Centrosomal protein 68","Uniprot":["Q76N32"],"Chromosome":"2","Position":"65056366-65087004","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"69.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040493","HPA040620"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"HPA040493":"AB_10673411","HPA040620":"AB_10794144"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"}},{"Gene":"CEP95","Gene synonym":["CCDC45","DKFZp667E1824"],"Ensembl":"ENSG00000258890","Gene description":"Centrosomal protein 95","Uniprot":["Q96GE4"],"Chromosome":"17","Position":"64506865-64542461","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"89.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052426","HPA052428","HPA061371"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA052426":"AB_2681827","HPA052428":"AB_2681829","HPA061371":"AB_2684495"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.78e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.76e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"}},{"Gene":"CEPT1","Gene synonym":[],"Ensembl":"ENSG00000134255","Gene description":"Choline\/ethanolamine phosphotransferase 1","Uniprot":["Q9Y6K0"],"Chromosome":"1","Position":"111139627-111185104","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.96e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"}},{"Gene":"CERKL","Gene synonym":["RP26"],"Ensembl":"ENSG00000188452","Gene description":"Ceramide kinase like","Uniprot":["Q49MI3"],"Chromosome":"2","Position":"181536672-181680665","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"17.1","retina":"16.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"19.0","Endometrial ciliated cells":"44.0","Respiratory ciliated cells":"25.3","Rod photoreceptor cells":"26.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"9.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"2.7","Neuroblastoma":"2.5"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Lung - NK-cells (Lung)","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"14.5"},"Antibody":["HPA035443","HPA035444","HPA043203"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035443":"AB_2674625","HPA035444":"AB_10672093","HPA043203":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"}},{"Gene":"CERS1","Gene synonym":["LAG1","LASS1","UOG1"],"Ensembl":"ENSG00000223802","Gene description":"Ceramide synthase 1","Uniprot":["P27544"],"Chromosome":"19","Position":"18868545-18896727","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"298.6","choroid plexus":"92.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Late spermatids":"120.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"13.5","melanoma":"4.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Pancreas - Alpha cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045724"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA045724":"AB_10969762"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"}},{"Gene":"CERS2","Gene synonym":["FLJ10243","LASS2","SP260"],"Ensembl":"ENSG00000143418","Gene description":"Ceramide synthase 2","Uniprot":["Q96G23"],"Chromosome":"1","Position":"150960583-150975003","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"732.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"169.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Macrophages","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027262","HPA078737"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Nuclear membrane","Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA027262":"AB_1852717","HPA078737":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"}},{"Gene":"CERS3","Gene synonym":["LASS3","MGC27091"],"Ensembl":"ENSG00000154227","Gene description":"Ceramide synthase 3","Uniprot":["Q8IU89"],"Chromosome":"15","Position":"100400395-100544995","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"55.1","skin 1":"64.0","vagina":"30.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"32.1","Basal squamous epithelial cells":"39.0","Early spermatids":"24.0","Late spermatids":"18.6","Spermatocytes":"24.4","Squamous epithelial cells":"49.9","Suprabasal keratinocytes":"87.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"14.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"head and neck cancer":"11.9"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006092","HPA024356"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA006092":"AB_1079236","HPA024356":"AB_1852721"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"}},{"Gene":"CERS4","Gene synonym":["FLJ12089","LASS4","Trh1"],"Ensembl":"ENSG00000090661","Gene description":"Ceramide synthase 4","Uniprot":["Q9HA82"],"Chromosome":"19","Position":"8206736-8262421","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Muller glia cells":"124.7","Suprabasal keratinocytes":"83.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Liver - Hepatocytes","Prostate - Prostate glandular cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033734","HPA054729"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB033734":"AB_2132977","HPA054729":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.71e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.83e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.45e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.05e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.63e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"}},{"Gene":"CERS5","Gene synonym":["FLJ25304","LASS5","MGC45411","Trh4"],"Ensembl":"ENSG00000139624","Gene description":"Ceramide synthase 5","Uniprot":["Q8N5B7"],"Chromosome":"12","Position":"50129289-50167533","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"72.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006780","HPA026589"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nuclear membrane","Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA006780":null,"HPA026589":"AB_1852727"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.63e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.33e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.76e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"}},{"Gene":"CERS6","Gene synonym":["LASS6"],"Ensembl":"ENSG00000172292","Gene description":"Ceramide synthase 6","Uniprot":["Q6ZMG9"],"Chromosome":"2","Position":"168456249-168775134","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Inflammatory response","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"150.7","Excitatory neurons":"267.7","Inhibitory neurons":"286.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"5.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"5.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044683"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044683":"AB_10965059"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.31e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.10e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"}},{"Gene":"CES5A","Gene synonym":["CAUXIN","CES4C1","CES5","CES7","FLJ31547"],"Ensembl":"ENSG00000159398","Gene description":"Carboxylesterase 5A","Uniprot":["Q6NT32"],"Chromosome":"16","Position":"55846154-55956031","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Serine esterase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"epididymis":"67.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"1.5","Cholangiocytes":"1.9","Collecting duct cells":"3.9","Excitatory neurons":"1.4","Hepatocytes":"6.7","Oligodendrocyte precursor cells":"1.9","Oligodendrocytes":"3.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CETN3","Gene synonym":["CEN3"],"Ensembl":"ENSG00000153140","Gene description":"Centrin 3","Uniprot":["O15182"],"Chromosome":"5","Position":"90392257-90409766","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis","mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"130.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"389.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035608","HPA063704"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA035608":"AB_10601098","HPA063704":"AB_2685097"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.22e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"}},{"Gene":"CFAP251","Gene synonym":["CaM-IP4","MGC33630","WDR66"],"Ensembl":"ENSG00000158023","Gene description":"Cilia and flagella associated protein 251","Uniprot":["Q8TBY9"],"Chromosome":"12","Position":"121918592-122003927","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"22.3","testis":"19.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"38.3","Early spermatids":"41.9","Endometrial ciliated cells":"90.5","Late spermatids":"53.0","Respiratory ciliated cells":"125.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"plasmacytoid DC":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"1.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"14.7"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Lung - Respiratory ciliated cells","Skin - Outer root sheath cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039902","HPA040005"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039902":"AB_10795236","HPA040005":"AB_10795160"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"}},{"Gene":"CFAP299","Gene synonym":["C4orf22"],"Ensembl":"ENSG00000197826","Gene description":"Cilia and flagella associated protein 299","Uniprot":["Q6V702"],"Chromosome":"4","Position":"80335730-80963750","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"fallopian tube":"19.8","testis":"27.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"150.0","Endometrial ciliated cells":"51.9","Excitatory neurons":"83.1","Late spermatids":"29.4","Respiratory ciliated cells":"61.5","Spermatocytes":"67.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"2.2"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043383"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043383":"AB_10797140"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"}},{"Gene":"CFAP36","Gene synonym":["BARTL1","CCDC104","MGC15407"],"Ensembl":"ENSG00000163001","Gene description":"Cilia and flagella associated protein 36","Uniprot":["Q96G28"],"Chromosome":"2","Position":"55519604-55545079","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1289.7","Late spermatids":"469.4","Spermatocytes":"307.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008994","HPA017061"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA008994":"AB_2275429","HPA017061":"AB_1846129"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"}},{"Gene":"CFAP43","Gene synonym":["bA373N18.2","C10orf79","FLJ22944","FLJ36006","WDR96"],"Ensembl":"ENSG00000197748","Gene description":"Cilia and flagella associated protein 43","Uniprot":["Q8NDM7"],"Chromosome":"10","Position":"104129888-104232364","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"34.7","choroid plexus":"80.2","fallopian tube":"48.9","testis":"57.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"107.8","Endometrial ciliated cells":"154.2","Late spermatids":"61.9","Respiratory ciliated cells":"141.5","Spermatocytes":"44.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"5.9"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"}},{"Gene":"CFAP46","Gene synonym":["bA288G11.4","bA288G11.5","bB137A17.2","bB137A17.3","C10orf123","C10orf124","C10orf92","C10orf93","DKFZp434A1721","FLJ25954","TTC40"],"Ensembl":"ENSG00000171811","Gene description":"Cilia and flagella associated protein 46","Uniprot":["Q8IYW2"],"Chromosome":"10","Position":"132808392-132942823","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"22.5","skeletal muscle":"33.4","testis":"41.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"56.9","Endometrial ciliated cells":"66.8","Excitatory neurons":"42.1","Respiratory ciliated cells":"84.3","Rod photoreceptor cells":"88.9","Spermatocytes":"49.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037786","HPA038034","HPA038867","HPA038868"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037786":"AB_10672392","HPA038034":"AB_2675796","HPA038867":"AB_2676246","HPA038868":"AB_2676247"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"}},{"Gene":"CFAP47","Gene synonym":["CHDC2","CXorf22","CXorf30","CXorf59","FLJ36601","MGC34831","RP13-11B7.1"],"Ensembl":"ENSG00000165164","Gene description":"Cilia and flagella associated protein 47","Uniprot":["Q6ZTR5"],"Chromosome":"X","Position":"35919734-36385317","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.1","choroid plexus":"7.1","fallopian tube":"4.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"44.0","Cone photoreceptor cells":"13.8","Endometrial ciliated cells":"65.2","Respiratory ciliated cells":"34.9","Rod photoreceptor cells":"12.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044633","HPA054859"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044633":"AB_10960684","HPA054859":"AB_2682627"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-3"}},{"Gene":"CFAP54","Gene synonym":["C12orf55","C12orf63","FLJ31514","FLJ44112"],"Ensembl":"ENSG00000188596","Gene description":"Cilia and flagella associated protein 54","Uniprot":["Q96N23"],"Chromosome":"12","Position":"96489571-96875555","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation","Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.7","choroid plexus":"30.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"26.3","Early spermatids":"35.6","Endometrial ciliated cells":"64.4","Excitatory neurons":"21.6","Oligodendrocytes":"45.1","Respiratory ciliated cells":"56.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039897"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Microtubules"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA039897":"AB_10674427"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"}},{"Gene":"CFAP57","Gene synonym":["FLJ32000","WDR65"],"Ensembl":"ENSG00000243710","Gene description":"Cilia and flagella associated protein 57","Uniprot":["Q96MR6"],"Chromosome":"1","Position":"43172330-43254358","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"10.7","fallopian tube":"23.4","testis":"15.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"46.2","Endometrial ciliated cells":"71.1","Late spermatids":"22.8","Respiratory ciliated cells":"55.9","Spermatocytes":"21.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"1.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"1.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"4.5"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002736","HPA028623"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002736":"AB_2272982","HPA028623":"AB_10603234"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.02e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"}},{"Gene":"CFAP74","Gene synonym":["C1orf222","FLJ45476","KIAA1751"],"Ensembl":"ENSG00000142609","Gene description":"Cilia and flagella associated protein 74","Uniprot":["Q9C0B2"],"Chromosome":"1","Position":"1921951-2003837","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"7.1","testis":"5.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"12.6","Endometrial ciliated cells":"34.3","Excitatory neurons":"11.5","Late spermatids":"19.8","Respiratory ciliated cells":"54.0","Spermatocytes":"14.7","Spermatogonia":"11.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Prostate - Prostate glandular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028521","HPA029274","HPA030240"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA028521":"AB_10601881","HPA029274":"AB_10601997","HPA030240":"AB_2732455"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"}},{"Gene":"CFC1","Gene synonym":["CRYPTIC","HTX2"],"Ensembl":"ENSG00000136698","Gene description":"Cripto, FRL-1, cryptic family 1","Uniprot":["P0CG37"],"Chromosome":"2","Position":"130592165-130599575","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":["Gastrulation"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Heterotaxy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"24.0","pancreas":"30.7","pituitary gland":"59.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"12.8","Enteroendocrine cells":"8.5","Pancreatic endocrine cells":"20.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"pancreatic cancer":"4.3"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hypothalamus":"24.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"prostate cancer":"15.2","testis cancer":"4.0"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041773"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041773":"AB_2677664"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CFC1B","Gene synonym":[],"Ensembl":"ENSG00000152093","Gene description":"Cripto, FRL-1, cryptic family 1B","Uniprot":["P0CG36"],"Chromosome":"2","Position":"130521197-130528604","Protein class":["Predicted secreted proteins"],"Biological process":["Gastrulation"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"2.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Bipolar cells":"1.3","Gastric mucus-secreting cells":"1.2","Pancreatic endocrine cells":"1.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041773"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041773":"AB_2677664"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CFTR","Gene synonym":["ABC35","ABCC7","CF","CFTR\/MRP","dJ760C5.1","MRP7","TNR-CFTR"],"Ensembl":"ENSG00000001626","Gene description":"CF transmembrane conductance regulator","Uniprot":["P13569"],"Chromosome":"7","Position":"117287120-117715971","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Isomerase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"54.6","intestine":"42.7","pancreas":"210.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Ductal cells":"559.5","Late spermatids":"152.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"23.9","pancreatic cancer":"28.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"21.7","Gastric cancer":"10.4"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Colon - Colon enterocytes","Lung - Alveolar cells type 2","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001951","HPA021939","HPA079652"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001951":null,"HPA021939":"AB_1846578","HPA079652":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.44e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"}},{"Gene":"CGREF1","Gene synonym":["CGR11"],"Ensembl":"ENSG00000138028","Gene description":"Cell growth regulator with EF-hand domain 1","Uniprot":["Q99674"],"Chromosome":"2","Position":"27098889-27119128","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Cell cycle","Growth arrest"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"28.3","salivary gland":"25.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"10.9","Breast myoepithelial cells":"12.0","Excitatory neurons":"16.3","Horizontal cells":"12.2","Inhibitory neurons":"15.5","Oligodendrocyte precursor cells":"12.0","Spermatogonia":"14.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008241","HPA071103"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"700000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA008241":"AB_1846605","HPA071103":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.18e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.57e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"}},{"Gene":"CGRRF1","Gene synonym":["CGR19","RNF197"],"Ensembl":"ENSG00000100532","Gene description":"Cell growth regulator with ring finger domain 1","Uniprot":["Q99675"],"Chromosome":"14","Position":"54509812-54539292","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Growth arrest"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"155.1","Spermatocytes":"103.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002930"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA002930":"AB_1078507"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.84e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.57e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"}},{"Gene":"CH25H","Gene synonym":[],"Ensembl":"ENSG00000138135","Gene description":"Cholesterol 25-hydroxylase","Uniprot":["O95992"],"Chromosome":"10","Position":"89205629-89207317","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"35.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"130.8","Basal squamous epithelial cells":"147.6","Macrophages":"45.2","monocytes":"166.4","Smooth muscle cells":"61.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"2.5","Uterine cancer":"4.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"spinal cord":"6.3"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"}},{"Gene":"CHD4","Gene synonym":["Mi-2b","Mi2-BETA"],"Ensembl":"ENSG00000111642","Gene description":"Chromodomain helicase DNA binding protein 4","Uniprot":["Q14839"],"Chromosome":"12","Position":"6570082-6614524","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012008"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA012008":"AB_1846633"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"}},{"Gene":"CHEK1","Gene synonym":["CHK1"],"Ensembl":"ENSG00000149554","Gene description":"Checkpoint kinase 1","Uniprot":["O14757"],"Chromosome":"11","Position":"125625665-125676255","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"25.7","lymphoid tissue":"20.7","seminal vesicle":"29.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"109.9","Erythroid cells":"30.4","Extravillous trophoblasts":"37.0","Spermatocytes":"48.9","Spermatogonia":"39.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"6.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.7","T-cells":"6.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044364"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA044364":"AB_2678913"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.70e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.10e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"}},{"Gene":"CHEK2","Gene synonym":["bA444G7","CDS1","CHK2","HuCds1","PP1425","RAD53"],"Ensembl":"ENSG00000183765","Gene description":"Checkpoint kinase 2","Uniprot":["O96017"],"Chromosome":"22","Position":"28687743-28742422","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cell cycle","Cell division","DNA damage","DNA repair","Host-virus interaction","Mitosis","Transcription","Transcription regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatogonia":"18.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Skin - Mitotic cells (Skin)","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001878","CAB002030"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB002030":"AB_563660","HPA001878":"AB_1078514"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.80e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"}},{"Gene":"CHIC1","Gene synonym":["BRX"],"Ensembl":"ENSG00000204116","Gene description":"Cysteine rich hydrophobic domain 1","Uniprot":["Q5VXU3"],"Chromosome":"X","Position":"73563200-73687102","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"45.5","Excitatory neurons":"61.7","Inhibitory neurons":"58.2","Oligodendrocyte precursor cells":"64.0","Oligodendrocytes":"71.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026782","HPA052062"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Nuclear speckles","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA026782":"AB_1846654","HPA052062":"AB_2681714"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.75e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"}},{"Gene":"CHIC2","Gene synonym":["BTL"],"Ensembl":"ENSG00000109220","Gene description":"Cysteine rich hydrophobic domain 2","Uniprot":["Q9UKJ5"],"Chromosome":"4","Position":"54009789-54064605","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"197.2","Suprabasal keratinocytes":"187.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"365.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026782","HPA026784","HPA076603"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA026782":"AB_1846654","HPA026784":"AB_2732433","HPA076603":"AB_2732317"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.56e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"}},{"Gene":"CHID1","Gene synonym":["FLJ42707","MGC3234","SI-CLP"],"Ensembl":"ENSG00000177830","Gene description":"Chitinase domain containing 1","Uniprot":["Q9BWS9"],"Chromosome":"11","Position":"867859-915058","Protein class":["Predicted intracellular proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"404.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039374"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Intermediate filaments"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA039374":"AB_10673609"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.76e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"}},{"Gene":"CHL1","Gene synonym":["CALL","FLJ44930","L1CAM2","MGC132578"],"Ensembl":"ENSG00000134121","Gene description":"Cell adhesion molecule L1 like","Uniprot":["O00533"],"Chromosome":"3","Position":"196763-409417","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"216.7","Excitatory neurons":"418.1","Inhibitory neurons":"313.2","Oligodendrocyte precursor cells":"879.4","Schwann cells":"409.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"15.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"33","RNA blood cell specific nTPM":{"memory B-cell":"2.7","naive B-cell":"3.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"38","RNA blood lineage specific nTPM":{"B-cells":"3.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Rhabdoid":"37.2","skin cancer":"32.1"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003345","CAB026120"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5800000000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026120":null,"HPA003345":"AB_1078516"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"}},{"Gene":"CHML","Gene synonym":["REP-2"],"Ensembl":"ENSG00000203668","Gene description":"CHM like Rab escort protein","Uniprot":["P26374"],"Chromosome":"1","Position":"241628851-241640369","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"161.2","monocytes":"97.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029627","HPA029628","HPA062967"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029627":"AB_2756314","HPA029628":"AB_10603784","HPA062967":"AB_2797269"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.23e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"CHMP2A","Gene synonym":["BC-2","CHMP2","VPS2","VPS2A"],"Ensembl":"ENSG00000130724","Gene description":"Charged multivesicular body protein 2A","Uniprot":["O43633"],"Chromosome":"19","Position":"58551566-58555105","Protein class":["Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041153","HPA042031"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"230000","Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA041153":"AB_10964358","HPA042031":"AB_10961727"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"}},{"Gene":"CHMP6","Gene synonym":["FLJ11749","VPS20"],"Ensembl":"ENSG00000176108","Gene description":"Charged multivesicular body protein 6","Uniprot":["Q96FZ7"],"Chromosome":"17","Position":"80991598-81009517","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023001","HPA024460"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023001":"AB_1848689","HPA024460":"AB_1848691"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.99e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-3"}},{"Gene":"CHN1","Gene synonym":["ARHGAP2","CHN","DURS2","n-chimerin","RhoGAP2"],"Ensembl":"ENSG00000128656","Gene description":"Chimerin 1","Uniprot":["P15882"],"Chromosome":"2","Position":"174798809-175005381","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Neurogenesis"],"Molecular function":["GTPase activation"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"772.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"189.2","Excitatory neurons":"588.0","Horizontal cells":"96.8","Inhibitory neurons":"109.0","Microglial cells":"94.9","Oligodendrocyte precursor cells":"143.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"18.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory CD4 T-cell":"6.5","memory CD8 T-cell":"2.1","T-reg":"8.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"T-cells":"8.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Prostate - Fibroblasts","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036111"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036111":"AB_10671241"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"}},{"Gene":"CHODL","Gene synonym":["C21orf68","FLJ12627","MT75","PRED12"],"Ensembl":"ENSG00000154645","Gene description":"Chondrolectin","Uniprot":["Q9H9P2"],"Chromosome":"21","Position":"17901263-18267373","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Neurogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.5","lymphoid tissue":"14.1","testis":"31.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"38.3","Granulosa cells":"11.9","Oligodendrocyte precursor cells":"12.0","Oligodendrocytes":"47.3","Theca cells":"32.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"6.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"MAIT T-cell":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"T-cells":"1.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"7.3"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Testis - Sertoli cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"3.9","hypothalamus":"12.3","pons and medulla":"10.9"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"olfactory bulb":"66.4","spinal cord":"38.6"},"Antibody":["HPA017282","HPA057559"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA017282":"AB_1846687","HPA057559":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.18e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"CHPF2","Gene synonym":["ChSy-3","CSGlcA-T","KIAA1402"],"Ensembl":"ENSG00000033100","Gene description":"Chondroitin polymerizing factor 2","Uniprot":["Q9P2E5"],"Chromosome":"7","Position":"151232489-151238827","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020992"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA020992":"AB_1847267"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.51e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-3"}},{"Gene":"CHPT1","Gene synonym":["CPT1"],"Ensembl":"ENSG00000111666","Gene description":"Choline phosphotransferase 1","Uniprot":["Q8WUD6"],"Chromosome":"12","Position":"101696947-101744140","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"662.4","Mucus glandular cells":"326.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"36.9","eosinophil":"14.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"36.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067643"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA067643":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.41e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"CHRFAM7A","Gene synonym":["CHRNA7-DR1","D-10"],"Ensembl":"ENSG00000166664","Gene description":"CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion","Uniprot":["Q494W8"],"Chromosome":"15","Position":"30360566-30393849","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"4.2","parathyroid gland":"5.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1.6","Horizontal cells":"1.9","Inhibitory neurons":"4.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"2.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"2.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"}},{"Gene":"CHRM1","Gene synonym":[],"Ensembl":"ENSG00000168539","Gene description":"Cholinergic receptor muscarinic 1","Uniprot":["P11229"],"Chromosome":"11","Position":"62908679-62921807","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"27.0","prostate":"29.6","salivary gland":"28.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Prostatic glandular cells":"49.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"16","RNA cancer specific FPKM":{"prostate cancer":"27.9"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"178","RNA brain regional specific nTPM":{"amygdala":"12.4","basal ganglia":"18.7","cerebral cortex":"27.0","hippocampal formation":"22.6","white matter":"8.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"breast cancer":"2.8","Neuroblastoma":"8.6","prostate cancer":"2.4"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells (progenitors)","Colon - Colon enteroendocrine cells","Prostate - Prostate glandular cells","Skin - Eccrine sweat gland cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014101"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014101":"AB_1854210"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"CHRM2","Gene synonym":[],"Ensembl":"ENSG00000181072","Gene description":"Cholinergic receptor muscarinic 2","Uniprot":["P08172"],"Chromosome":"7","Position":"136868652-137020255","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"36.1","intestine":"21.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Cardiomyocytes":"72.6","Excitatory neurons":"48.4","Inhibitory neurons":"115.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"10.4"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatic stellate cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022338","HPA029795"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022338":null,"HPA029795":"AB_10601357"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"}},{"Gene":"CHRM3","Gene synonym":[],"Ensembl":"ENSG00000133019","Gene description":"Cholinergic receptor muscarinic 3","Uniprot":["P20309"],"Chromosome":"1","Position":"239386565-239915452","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.8","salivary gland":"17.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"791.9","Inhibitory neurons":"606.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Smooth muscle cells","Skin - Eccrine sweat gland cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024106","HPA048036"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA024106":"AB_1854211","HPA048036":"AB_2680238"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"}},{"Gene":"CHRM4","Gene synonym":[],"Ensembl":"ENSG00000180720","Gene description":"Cholinergic receptor muscarinic 4","Uniprot":["P08173"],"Chromosome":"11","Position":"46385098-46386608","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"18.5","intestine":"6.8","lymphoid tissue":"15.9","testis":"5.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"basal ganglia":"18.5","cerebral cortex":"4.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Skin - Keratinocyte (granular)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"16.8"},"Antibody":["CAB022444","HPA072083"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB022444":null,"HPA072083":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"}},{"Gene":"CHRM5","Gene synonym":[],"Ensembl":"ENSG00000184984","Gene description":"Cholinergic receptor muscarinic 5","Uniprot":["P08912"],"Chromosome":"15","Position":"33968497-34067458","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"18.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Oligodendrocytes":"168.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"13.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013172"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013172":"AB_1854212"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"}},{"Gene":"CHRNA1","Gene synonym":["CHRNA"],"Ensembl":"ENSG00000138435","Gene description":"Cholinergic receptor nicotinic alpha 1 subunit","Uniprot":["P02708"],"Chromosome":"2","Position":"174747592-174787935","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"skeletal muscle":"170.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Skeletal myocytes":"152.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.8"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"13","RNA brain regional specific nTPM":{"cerebral cortex":"12.8","hippocampal formation":"5.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"39","RNA cell line specific nTPM":{"Sarcoma":"113.1"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071554"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA071554":"AB_2686416"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"}},{"Gene":"CHRNA10","Gene synonym":[],"Ensembl":"ENSG00000129749","Gene description":"Cholinergic receptor nicotinic alpha 10 subunit","Uniprot":["Q9GZZ6"],"Chromosome":"11","Position":"3665587-3671384","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"skeletal muscle":"47.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"3.5","Kupffer cells":"3.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"olfactory bulb":"7.2"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-3"}},{"Gene":"CHRNA2","Gene synonym":[],"Ensembl":"ENSG00000120903","Gene description":"Cholinergic receptor nicotinic alpha 2 subunit","Uniprot":["Q15822"],"Chromosome":"8","Position":"27459756-27479883","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"72.1","prostate":"29.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Horizontal cells":"28.8","Inhibitory neurons":"14.4","Prostatic glandular cells":"21.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"421","RNA cancer specific FPKM":{"prostate cancer":"30.2"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"72.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"34","RNA cell line specific nTPM":{"prostate cancer":"25.4"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048348"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytokinetic bridge"],"Antibody RRID":{"HPA048348":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"CHRNA3","Gene synonym":[],"Ensembl":"ENSG00000080644","Gene description":"Cholinergic receptor nicotinic alpha 3 subunit","Uniprot":["P32297"],"Chromosome":"15","Position":"78593052-78621295","Protein class":["Disease related genes","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"39.3","lymphoid tissue":"65.8","retina":"53.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"26","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"413.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"Neuroblastoma":"159.6"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029430"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA029430":"AB_10603785"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-1"}},{"Gene":"CHRNA4","Gene synonym":["BFNC","EBN","EBN1"],"Ensembl":"ENSG00000101204","Gene description":"Cholinergic receptor nicotinic alpha 4 subunit","Uniprot":["P43681"],"Chromosome":"20","Position":"63343223-63378401","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"28.8","liver":"58.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"24.7","Hepatocytes":"29.7","Horizontal cells":"50.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"1.0"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"midbrain":"21.8","pons":"20.5","thalamus":"33.5"},"Antibody":["CAB034064"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034064":"AB_2080535"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"CHRNA5","Gene synonym":[],"Ensembl":"ENSG00000169684","Gene description":"Cholinergic receptor nicotinic alpha 5 subunit","Uniprot":["P30532"],"Chromosome":"15","Position":"78565520-78595269","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"12.1","Spermatocytes":"15.0","Spermatogonia":"27.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054381"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA054381":"AB_2682468"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.64e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"}},{"Gene":"CHRNA6","Gene synonym":[],"Ensembl":"ENSG00000147434","Gene description":"Cholinergic receptor nicotinic alpha 6 subunit","Uniprot":["Q15825"],"Chromosome":"8","Position":"42752620-42796392","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"9.3","retina":"3.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Horizontal cells":"14.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"9.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"lymphoma":"4.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"midbrain":"20.2","thalamus":"6.3"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"midbrain":"76.1"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"}},{"Gene":"CHRNA7","Gene synonym":[],"Ensembl":"ENSG00000175344","Gene description":"Cholinergic receptor nicotinic alpha 7 subunit","Uniprot":["P36544"],"Chromosome":"15","Position":"31923438-32173018","Protein class":["FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"7.8","intestine":"9.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"31.6","Horizontal cells":"29.5","Inhibitory neurons":"30.0","Intestinal goblet cells":"31.3","Proximal enterocytes":"27.8","Spermatogonia":"16.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Neuroblastoma":"16.6"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029422","CAB033624"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033624":"AB_784835","HPA029422":"AB_10600863"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"}},{"Gene":"CHRNA9","Gene synonym":["NACHRA9"],"Ensembl":"ENSG00000174343","Gene description":"Cholinergic receptor nicotinic alpha 9 subunit","Uniprot":["Q9UGM1"],"Chromosome":"4","Position":"40335333-40355217","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"breast cancer":"2.5","glioma":"3.5","lung cancer":"0.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Rhabdoid":"15.5"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"basal ganglia":"1.0"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-3"}},{"Gene":"CHRNB1","Gene synonym":["CHRNB"],"Ensembl":"ENSG00000170175","Gene description":"Cholinergic receptor nicotinic beta 1 subunit","Uniprot":["P11230"],"Chromosome":"17","Position":"7445061-7457710","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"158.4","tongue":"57.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"39.0","Skeletal myocytes":"60.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005822","CAB011200"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011200":"AB_262151","HPA005822":"AB_1079484"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"}},{"Gene":"CHRNB2","Gene synonym":[],"Ensembl":"ENSG00000160716","Gene description":"Cholinergic receptor nicotinic beta 2 subunit","Uniprot":["P17787"],"Chromosome":"1","Position":"154567778-154580013","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.4","retina":"8.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"11.2","Cone photoreceptor cells":"17.2","Excitatory neurons":"5.7","Horizontal cells":"21.8","Inhibitory neurons":"7.6","Late spermatids":"11.4","Rod photoreceptor cells":"5.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"17.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"}},{"Gene":"CHRNB3","Gene synonym":[],"Ensembl":"ENSG00000147432","Gene description":"Cholinergic receptor nicotinic beta 3 subunit","Uniprot":["Q05901"],"Chromosome":"8","Position":"42697366-42737407","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"12.1","retina":"3.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"2.2","Horizontal cells":"7.0","Inhibitory neurons":"2.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"testis cancer":"0.6"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"12.1","midbrain":"10.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"2.1"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"midbrain":"6.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045555"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045555":"AB_10960891"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CHRNB4","Gene synonym":[],"Ensembl":"ENSG00000117971","Gene description":"Cholinergic receptor nicotinic beta 4 subunit","Uniprot":["P30926"],"Chromosome":"15","Position":"78624111-78727754","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"3.0","retina":"2.7","testis":"5.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"36.1","Late spermatids":"56.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"35","RNA cell line specific nTPM":{"Neuroblastoma":"31.6"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"olfactory bulb":"5.3","pons and medulla":"1.4","thalamus":"4.2"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059484"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA059484":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"}},{"Gene":"CHRND","Gene synonym":["ACHRD"],"Ensembl":"ENSG00000135902","Gene description":"Cholinergic receptor nicotinic delta subunit","Uniprot":["Q07001"],"Chromosome":"2","Position":"232525993-232536667","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"skeletal muscle":"57.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Skeletal myocytes":"33.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"head and neck cancer":"1.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"87","RNA cell line specific nTPM":{"Sarcoma":"27.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056404","HPA065404"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA056404":"AB_2732603","HPA065404":"AB_2732734"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"CHRNE","Gene synonym":["ACHRE"],"Ensembl":"ENSG00000108556","Gene description":"Cholinergic receptor nicotinic epsilon subunit","Uniprot":["Q04844"],"Chromosome":"17","Position":"4897771-4934438","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"heart muscle":"55.3","pituitary gland":"27.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"169.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"2.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"1.4"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"14","RNA pig brain regional specific nTPM":{"basal ganglia":"6.3"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"}},{"Gene":"CHRNG","Gene synonym":["ACHRG"],"Ensembl":"ENSG00000196811","Gene description":"Cholinergic receptor nicotinic gamma subunit","Uniprot":["P07510"],"Chromosome":"2","Position":"232539692-232548115","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"skeletal muscle":"32.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"42","RNA single cell type specific nTPM":{"Skeletal myocytes":"52.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"17","RNA cell line specific nTPM":{"Sarcoma":"6.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"}},{"Gene":"CHST10","Gene synonym":["HNK-1ST"],"Ensembl":"ENSG00000115526","Gene description":"Carbohydrate sulfotransferase 10","Uniprot":["O43529"],"Chromosome":"2","Position":"100391860-100417668","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism","Lipid metabolism","Steroid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"33.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"20.9","Horizontal cells":"14.7","Muller glia cells":"13.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012884","HPA051545"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"680000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA012884":"AB_1846710","HPA051545":"AB_2681529"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.05e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"}},{"Gene":"CHST11","Gene synonym":["C4ST","C4St-1","C4ST1","HSA269537"],"Ensembl":"ENSG00000171310","Gene description":"Carbohydrate sulfotransferase 11","Uniprot":["Q9NPF2"],"Chromosome":"12","Position":"104455295-104762014","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"39.0","choroid plexus":"59.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Microglial cells":"273.6","Oligodendrocyte precursor cells":"969.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"12.7","eosinophil":"11.2","neutrophil":"15.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"15.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052828"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA052828":"AB_2681966"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.59e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.42e-4"}},{"Gene":"CHST12","Gene synonym":["C4S-2","C4ST2"],"Ensembl":"ENSG00000136213","Gene description":"Carbohydrate sulfotransferase 12","Uniprot":["Q9NRB3"],"Chromosome":"7","Position":"2403588-2448484","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"274.2","Syncytiotrophoblasts":"136.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041680"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"960000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA041680":"AB_10959789"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"}},{"Gene":"CHST14","Gene synonym":["D4ST-1","D4ST1","HD4ST"],"Ensembl":"ENSG00000169105","Gene description":"Carbohydrate sulfotransferase 14","Uniprot":["Q8NCH0"],"Chromosome":"15","Position":"40470984-40473158","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"46.0","Extravillous trophoblasts":"31.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"7.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057697","HPA071601"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA057697":"AB_2683505","HPA071601":"AB_2686425"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"}},{"Gene":"CHST15","Gene synonym":["BRAG","GALNAC4S-6ST","KIAA0598"],"Ensembl":"ENSG00000182022","Gene description":"Carbohydrate sulfotransferase 15","Uniprot":["Q7LFX5"],"Chromosome":"10","Position":"124007668-124093598","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"59.6","monocytes":"77.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"69.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"69.0","monocytes":"38.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017584"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"690000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA017584":"AB_1849437"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.22e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"}},{"Gene":"CHST2","Gene synonym":["C6ST"],"Ensembl":"ENSG00000175040","Gene description":"Carbohydrate sulfotransferase 2","Uniprot":["Q9Y4C5"],"Chromosome":"3","Position":"143119771-143124014","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism","Inflammatory response"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"48.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"75.0","Muller glia cells":"94.1","NK-cells":"148.2","Plasma cells":"83.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"4.3","NK-cell":"4.9","non-classical monocyte":"11.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"11.4","NK-cells":"4.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013620"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA013620":"AB_2668861"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"CHST3","Gene synonym":["C6ST","C6ST1"],"Ensembl":"ENSG00000122863","Gene description":"Carbohydrate sulfotransferase 3","Uniprot":["Q7LGC8"],"Chromosome":"10","Position":"71964395-72013558","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"28.6","Sertoli cells":"35.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Macrophages","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047523","HPA055704"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"690000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA047523":"AB_2680075","HPA055704":"AB_2682891"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-3"}},{"Gene":"CHST5","Gene synonym":["FLJ22167","I-GLCNAC-6-ST"],"Ensembl":"ENSG00000135702","Gene description":"Carbohydrate sulfotransferase 5","Uniprot":["Q9GZS9"],"Chromosome":"16","Position":"75528535-75535247","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"intestine":"85.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"4.0","Enteroendocrine cells":"6.3","Intestinal goblet cells":"6.3","Paneth cells":"3.2","Proximal enterocytes":"10.0","Undifferentiated cells":"2.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"colorectal cancer":"1.4","stomach cancer":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"3.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043804","HPA068029"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043804":"AB_10960563","HPA068029":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"}},{"Gene":"CHST9","Gene synonym":["GALNAC-4-ST2","GALNAC4ST-2"],"Ensembl":"ENSG00000154080","Gene description":"Carbohydrate sulfotransferase 9","Uniprot":["Q7L1S5"],"Chromosome":"18","Position":"26906481-27185308","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"13.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"132.0","Ionocytes":"90.5","Oligodendrocyte precursor cells":"160.3","Respiratory ciliated cells":"189.7","Salivary duct cells":"113.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"5.9","liver cancer":"10.0"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Cardiomyocytes","Lung - Respiratory ciliated cells","Skin - Outer root sheath cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011393"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011393":"AB_1846733"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-3"}},{"Gene":"CHTF18","Gene synonym":["C16orf41","C321D2.4","CHL12","Ctf18"],"Ensembl":"ENSG00000127586","Gene description":"Chromosome transmission fidelity factor 18","Uniprot":["Q8WVB6"],"Chromosome":"16","Position":"788046-800737","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA replication"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"11.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"23.4","Erythroid cells":"20.2","Extravillous trophoblasts":"20.2","Granulosa cells":"23.4","Spermatogonia":"21.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Mitotic cells (Stomach)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040976","HPA056209"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA040976":"AB_2677232","HPA056209":"AB_2683066"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.43e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.78e-4"}},{"Gene":"CIB1","Gene synonym":["CIB","KIP","SIP2-28"],"Ensembl":"ENSG00000185043","Gene description":"Calcium and integrin binding 1","Uniprot":["Q99828"],"Chromosome":"15","Position":"90229975-90234047","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Angiogenesis","Apoptosis","Cell adhesion","Cell cycle","Cell division","Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"1407.8","Respiratory ciliated cells":"946.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012991","HPA042413","HPA048825","HPA074310"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB012991":"AB_2533205","HPA042413":"AB_2732498","HPA048825":"AB_2680533","HPA074310":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.26e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"}},{"Gene":"CIP2A","Gene synonym":["KIAA1524"],"Ensembl":"ENSG00000163507","Gene description":"Cellular inhibitor of PP2A","Uniprot":["Q8TCG1"],"Chromosome":"3","Position":"108549864-108589644","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"7.5","lymphoid tissue":"6.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"101.6","Erythroid cells":"31.0","Spermatocytes":"39.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039570"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA039570":"AB_10796329"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.24e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"CISD1","Gene synonym":["C10orf70","MDS029","mitoNEET","ZCD1"],"Ensembl":"ENSG00000122873","Gene description":"CDGSH iron sulfur domain 1","Uniprot":["Q9NZ45"],"Chromosome":"10","Position":"58269162-58289586","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"82.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"441.5","Distal tubular cells":"634.4","Proximal enterocytes":"552.0","Proximal tubular cells":"731.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074383"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA074383":"AB_2686684"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.69e-4"}},{"Gene":"CISD2","Gene synonym":["ERIS","Miner1","NAF-1","WFS2","ZCD2"],"Ensembl":"ENSG00000145354","Gene description":"CDGSH iron sulfur domain 2","Uniprot":["Q8N5K1"],"Chromosome":"4","Position":"102868974-102892807","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Deafness","Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"46.0"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015914"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA015914":"AB_1846794"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"CKLF","Gene synonym":["C32","CKLF1","CKLF3","CKLF4","HSPC224","UCK-1"],"Ensembl":"ENSG00000217555","Gene description":"Chemokine like factor","Uniprot":["Q9UBR5"],"Chromosome":"16","Position":"66552563-66566251","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Chemotaxis"],"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"302.1","Hofbauer cells":"294.3","Langerhans cells":"260.6","Spermatocytes":"270.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1384.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062779"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA062779":"AB_2684867"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.67e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.22e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"CKLF-CMTM1","Gene synonym":[],"Ensembl":"ENSG00000254788","Gene description":"CKLF-CMTM1 readthrough","Uniprot":[],"Chromosome":"16","Position":"66552587-66579135","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"5.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"2.0","Early spermatids":"1.5","Late spermatids":"7.2","Sertoli cells":"2.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017136"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017136":"AB_1846992"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"CKMT2","Gene synonym":["SMTCK"],"Ensembl":"ENSG00000131730","Gene description":"Creatine kinase, mitochondrial 2","Uniprot":["P17540"],"Chromosome":"5","Position":"81233320-81266398","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"49","RNA tissue specific nTPM":{"heart muscle":"1240.1","skeletal muscle":"1430.8","tongue":"2324.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Cardiomyocytes":"1007.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"NK-cell":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"NK-cells":"1.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"7.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Heart muscle - Cardiomyocytes","Kidney - Intercalated cells","Prostate - Smooth muscle cells","Skin - Eccrine sweat gland cells","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051880"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3000000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051880":"AB_2681650"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-3"}},{"Gene":"CLASP2","Gene synonym":["KIAA0627"],"Ensembl":"ENSG00000163539","Gene description":"Cytoplasmic linker associated protein 2","Uniprot":["O75122"],"Chromosome":"3","Position":"33496245-33718356","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"176.6","retina":"126.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"285.3","Excitatory neurons":"506.7","Inhibitory neurons":"514.1","Oligodendrocyte precursor cells":"708.5","Oligodendrocytes":"1242.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067071"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA067071":"AB_2685775"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.48e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"}},{"Gene":"CLASRP","Gene synonym":["CLASP","SFRS16","SWAP2"],"Ensembl":"ENSG00000104859","Gene description":"CLK4 associating serine\/arginine rich protein","Uniprot":["Q8N2M8"],"Chromosome":"19","Position":"45039045-45070956","Protein class":["Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060469","HPA062455"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA060469":"AB_2684289","HPA062455":"AB_2684770"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.77e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.69e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.02e-5"}},{"Gene":"CLCA2","Gene synonym":["CLCRG2"],"Ensembl":"ENSG00000137975","Gene description":"Chloride channel accessory 2","Uniprot":["Q9UQC9"],"Chromosome":"1","Position":"86424171-86456553","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion","Ion transport","Transport"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"117.5","skin 1":"88.7","vagina":"53.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"125.2","Basal respiratory cells":"51.5","Basal squamous epithelial cells":"63.4","Club cells":"63.0","Squamous epithelial cells":"185.4","Suprabasal keratinocytes":"213.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"146.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"17.3","head and neck cancer":"33.1"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Prostate - Urothelial cells","Skin - Mitotic cells (Skin)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047192"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"96000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA047192":"AB_2679977"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"}},{"Gene":"CLCA4","Gene synonym":["CaCC2"],"Ensembl":"ENSG00000016602","Gene description":"Chloride channel accessory 4","Uniprot":["Q14CN2"],"Chromosome":"1","Position":"86547078-86580754","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"373.9","intestine":"257.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Club cells":"71.7","Distal enterocytes":"227.9","Paneth cells":"120.4","Squamous epithelial cells":"194.3","Suprabasal keratinocytes":"98.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"21.4","urothelial cancer":"15.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Bladder cancer":"13.5","cervical cancer":"5.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017045","HPA064770"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Aggresome"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Aggresome"],"Antibody RRID":{"HPA017045":"AB_2291679","HPA064770":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.47e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.63e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"}},{"Gene":"CLCC1","Gene synonym":["MCLC"],"Ensembl":"ENSG00000121940","Gene description":"Chloride channel CLIC like 1","Uniprot":["Q96S66"],"Chromosome":"1","Position":"108927361-108963504","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009087","HPA013210"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA009087":"AB_1078532","HPA013210":"AB_1846895"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"}},{"Gene":"CLCN1","Gene synonym":["ClC-1","CLC1"],"Ensembl":"ENSG00000188037","Gene description":"Chloride voltage-gated channel 1","Uniprot":["P35523"],"Chromosome":"7","Position":"143316111-143352083","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"skeletal muscle":"65.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Late spermatids":"152.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Gallbladder cancer":"3.0"},"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"}},{"Gene":"CLCN2","Gene synonym":["ClC-2","CLC2","EJM6"],"Ensembl":"ENSG00000114859","Gene description":"Chloride voltage-gated channel 2","Uniprot":["P51788"],"Chromosome":"3","Position":"184346185-184361650","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"16.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"64.2","Proximal enterocytes":"30.2","Theca cells":"45.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009397","HPA014545","HPA024108"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009397":"AB_2079256","HPA014545":"AB_1846881","HPA024108":"AB_1846883"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.67e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"}},{"Gene":"CLCN3","Gene synonym":["ClC-3","CLC3"],"Ensembl":"ENSG00000109572","Gene description":"Chloride voltage-gated channel 3","Uniprot":["P51790"],"Chromosome":"4","Position":"169612633-169723673","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Antiport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044723"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA044723":"AB_10959733"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.10e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"}},{"Gene":"CLCN4","Gene synonym":["ClC-4","CLC4"],"Ensembl":"ENSG00000073464","Gene description":"Chloride voltage-gated channel 4","Uniprot":["P51793"],"Chromosome":"X","Position":"10156975-10237660","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"33.3","retina":"37.9","skeletal muscle":"45.0","tongue":"34.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"75.2","Cone photoreceptor cells":"144.8","Excitatory neurons":"45.0","Horizontal cells":"59.0","Inhibitory neurons":"52.7","Oligodendrocytes":"72.3","Rod photoreceptor cells":"45.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"2.6","neutrophil":"2.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"2.6","granulocytes":"2.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031313","HPA063637"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA031313":"AB_10601358","HPA063637":"AB_2685069"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.13e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.55e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"}},{"Gene":"CLCN5","Gene synonym":["ClC-5","CLC5","DENTS","hCIC-K2","hClC-K2","NPHL1","NPHL2","XLRH","XRN"],"Ensembl":"ENSG00000171365","Gene description":"Chloride voltage-gated channel 5","Uniprot":["P51795"],"Chromosome":"X","Position":"49922596-50099235","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Antiport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"epididymis":"23.7","kidney":"46.2","liver":"16.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"49.9","Microglial cells":"45.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"9.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"2.6","plasmacytoid DC":"2.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000401","HPA003213"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA000401":"AB_1078531","HPA003213":"AB_2666843"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.20e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.05e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"}},{"Gene":"CLCN6","Gene synonym":["CLC-6","KIAA0046"],"Ensembl":"ENSG00000011021","Gene description":"Chloride voltage-gated channel 6","Uniprot":["P51797"],"Chromosome":"1","Position":"11806096-11848079","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Antiport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"64.7","Horizontal cells":"48.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032097"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA032097":"AB_10670827"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"}},{"Gene":"CLCN7","Gene synonym":["CLC-7","CLC7","OPTA2","PPP1R63"],"Ensembl":"ENSG00000103249","Gene description":"Chloride voltage-gated channel 7","Uniprot":["P51798"],"Chromosome":"16","Position":"1444934-1475084","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Osteopetrosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Melanocytes":"78.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"42.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043019","HPA043586"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043019":"AB_10964727","HPA043586":"AB_10965322"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.23e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"}},{"Gene":"CLCNKA","Gene synonym":["hClC-Ka"],"Ensembl":"ENSG00000186510","Gene description":"Chloride voltage-gated channel Ka","Uniprot":["P51800"],"Chromosome":"1","Position":"16018875-16034050","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Bartter syndrome","Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"kidney":"344.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Late spermatids":"219.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"renal cancer":"4.4","thyroid cancer":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"thyroid cancer":"7.3"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Lung - Respiratory ciliated cells","Skin - Eccrine sweat gland cells","Stomach - Parietal cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057717"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057717":"AB_2683509"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"}},{"Gene":"CLCNKB","Gene synonym":["hClC-Kb"],"Ensembl":"ENSG00000184908","Gene description":"Chloride voltage-gated channel Kb","Uniprot":["P51801"],"Chromosome":"1","Position":"16043736-16057308","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Voltage-gated channel"],"Disease involvement":["Bartter syndrome","Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"kidney":"209.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"25.6","Distal tubular cells":"28.0","Early spermatids":"12.6","Ionocytes":"15.0","Late spermatids":"82.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"renal cancer":"24.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"7.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Cardiomyocytes","Kidney - Intercalated cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057717"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057717":"AB_2683509"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.27e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"}},{"Gene":"CLDN1","Gene synonym":["ILVASC","SEMP1"],"Ensembl":"ENSG00000163347","Gene description":"Claudin 1","Uniprot":["O95832"],"Chromosome":"3","Position":"190305707-190322446","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"309.8","skin 1":"288.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"275.1","Basal prostatic cells":"242.9","Basal respiratory cells":"212.0","Basal squamous epithelial cells":"211.0","Ductal cells":"201.0","Salivary duct cells":"241.9","Squamous epithelial cells":"294.6","Suprabasal keratinocytes":"483.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Pancreas - Ductal cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"12","RNA pig brain regional specific nTPM":{"spinal cord":"25.4"},"Antibody":["CAB002602","HPA048319"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002602":null,"HPA048319":"AB_2680355"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.00e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.23e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"}},{"Gene":"CLDN10","Gene synonym":["CPETRL3","OSP-L"],"Ensembl":"ENSG00000134873","Gene description":"Claudin 10","Uniprot":["P78369"],"Chromosome":"13","Position":"95433604-95579759","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"135.2","pancreas":"216.5","salivary gland":"91.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"198.8","Cholangiocytes":"369.5","Club cells":"170.5","Ductal cells":"387.3","Glandular and luminal cells":"271.9","Ionocytes":"358.6","Proximal tubular cells":"233.7","Serous glandular cells":"168.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"19.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"eosinophil":"1.3","neutrophil":"4.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"4.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"testis cancer":"73.3"},"RNA tissue cell type enrichment":["Liver - Cholangiocyte","Skin - Eccrine sweat gland cells","Testis - Spermatocytes","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012969","HPA042348"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB012969":"AB_2533386","HPA042348":"AB_2677955"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.46e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.13e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"}},{"Gene":"CLDN11","Gene synonym":["OSP","OTM"],"Ensembl":"ENSG00000013297","Gene description":"Claudin 11","Uniprot":["O75508"],"Chromosome":"3","Position":"170418868-170454733","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"130.1","ovary":"95.4","testis":"116.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Leydig cells":"102.9","Oligodendrocytes":"372.4","Sertoli cells":"309.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"11.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"29.5"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"white matter":"2084.8"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009789","HPA013166","HPA013657"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Lipid droplets","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Lipid droplets"],"Antibody RRID":{"CAB009789":"AB_639330","HPA013166":"AB_1854821","HPA013657":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.31e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"}},{"Gene":"CLDN12","Gene synonym":[],"Ensembl":"ENSG00000157224","Gene description":"Claudin 12","Uniprot":["P56749"],"Chromosome":"7","Position":"90383721-90513402","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"145.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026945"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026945":"AB_10603786"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.36e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"}},{"Gene":"CLDN14","Gene synonym":["DFNB29"],"Ensembl":"ENSG00000159261","Gene description":"Claudin 14","Uniprot":["O95500"],"Chromosome":"21","Position":"36460621-36576569","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"kidney":"13.8","liver":"39.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"3.8","Distal tubular cells":"9.3","Ductal cells":"11.8","Exocrine glandular cells":"7.5","Glandular and luminal cells":"4.7","Hepatocytes":"18.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"liver cancer":"7.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"1.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"9.1"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054707"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA054707":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.53e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"}},{"Gene":"CLDN15","Gene synonym":[],"Ensembl":"ENSG00000106404","Gene description":"Claudin 15","Uniprot":["P56746"],"Chromosome":"7","Position":"101232092-101238820","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"adipose tissue":"65.4","intestine":"259.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"579.6","Thymic epithelial cells":"199.2","Undifferentiated cells":"129.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.30e-4"}},{"Gene":"CLDN16","Gene synonym":["HOMG3","PCLN1"],"Ensembl":"ENSG00000113946","Gene description":"Claudin 16","Uniprot":["Q9Y5I7"],"Chromosome":"3","Position":"190322541-190412138","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"kidney":"63.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Distal tubular cells":"121.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"ovarian cancer":"39.8","thyroid cancer":"29.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"ovarian cancer":"124.1","Uterine cancer":"158.7"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Ascending Loop of Henle cells","Liver - Hepatocytes","Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056020"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056020":"AB_2683011"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"}},{"Gene":"CLDN17","Gene synonym":["MGC126552","MGC126554"],"Ensembl":"ENSG00000156282","Gene description":"Claudin 17","Uniprot":["P56750"],"Chromosome":"21","Position":"30165565-30166805","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"cervix":"2.3","esophagus":"6.1","salivary gland":"6.4","vagina":"7.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"5.8","Suprabasal keratinocytes":"5.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"head and neck cancer":"2.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045903"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045903":"AB_2679491"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CLDN18","Gene synonym":["SFTPJ"],"Ensembl":"ENSG00000066405","Gene description":"Claudin 18","Uniprot":["P56856"],"Chromosome":"3","Position":"137998735-138033655","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"50","RNA tissue specific nTPM":{"lung":"252.2","stomach 1":"724.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"32","RNA single cell type specific nTPM":{"Alveolar cells type 1":"669.2","Alveolar cells type 2":"349.1","Gastric mucus-secreting cells":"1104.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"pancreatic cancer":"113.6","stomach cancer":"186.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"19.2","pancreatic cancer":"9.8"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Stomach - Gastric mucous cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013010","CAB013243","HPA018446"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB013010":"AB_2533382","CAB013243":"AB_2533383","HPA018446":"AB_2669866"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"}},{"Gene":"CLDN19","Gene synonym":[],"Ensembl":"ENSG00000164007","Gene description":"Claudin 19","Uniprot":["Q8N6F1"],"Chromosome":"1","Position":"42733093-42740254","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"choroid plexus":"19.8","kidney":"39.1","placenta":"9.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"265.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"liver cancer":"2.9","testis cancer":"3.5"},"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"5.4"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"spinal cord":"41.8"},"Antibody":["HPA014412"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014412":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"}},{"Gene":"CLDN2","Gene synonym":[],"Ensembl":"ENSG00000165376","Gene description":"Claudin 2","Uniprot":["P57739"],"Chromosome":"X","Position":"106900164-106930861","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"114.7","gallbladder":"101.6","kidney":"165.2","seminal vesicle":"90.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"74.6","Exocrine glandular cells":"55.0","Hepatocytes":"26.0","Proximal enterocytes":"31.8","Proximal tubular cells":"89.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"53.3","liver cancer":"24.6","pancreatic cancer":"48.5","renal cancer":"87.2","stomach cancer":"30.5"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"hippocampal formation":"8.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bile duct cancer":"124.8","colorectal cancer":"47.8","Gastric cancer":"48.7","Kidney cancer":"97.3","liver cancer":"33.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"4.5","hippocampal formation":"9.5","pons and medulla":"10.3","thalamus":"8.9"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"medulla oblongata":"1.7"},"Antibody":["CAB002609","HPA051548"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Nucleoplasm","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB002609":null,"HPA051548":"AB_2681530"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"}},{"Gene":"CLDN20","Gene synonym":[],"Ensembl":"ENSG00000171217","Gene description":"Claudin 20","Uniprot":["P56880"],"Chromosome":"6","Position":"155264013-155276548","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.3","Excitatory neurons":"1.7","Inhibitory neurons":"1.6","Oligodendrocytes":"2.0","Schwann cells":"1.2","Sertoli cells":"2.8","Suprabasal keratinocytes":"1.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"}},{"Gene":"CLDN22","Gene synonym":["CLDN21"],"Ensembl":"ENSG00000177300","Gene description":"Claudin 22","Uniprot":["Q8N7P3"],"Chromosome":"4","Position":"183318100-183320276","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"salivary gland":"4.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"29.5","Glandular and luminal cells":"56.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CLDN23","Gene synonym":["CLDNL"],"Ensembl":"ENSG00000253958","Gene description":"Claudin 23","Uniprot":["Q96B33"],"Chromosome":"8","Position":"8701937-8704096","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"16.4","stomach 1":"15.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"268.6","Gastric mucus-secreting cells":"62.6","Paneth cells":"186.0","Proximal enterocytes":"101.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"1.3","plasmacytoid DC":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Ductal cells","Skin - Keratinocyte (granular)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061306"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane","Cell Junctions"],"Antibody RRID":{"HPA061306":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.46e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.65e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"}},{"Gene":"CLDN24","Gene synonym":["CLDN21"],"Ensembl":"ENSG00000185758","Gene description":"Claudin 24","Uniprot":["A6NM45"],"Chromosome":"4","Position":"183321764-183322426","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"lymphoma":"3.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CLDN25","Gene synonym":[],"Ensembl":"ENSG00000228607","Gene description":"Claudin 25","Uniprot":["C9JDP6"],"Chromosome":"11","Position":"113779747-113780500","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053555"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053555":"AB_2682186"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CLDN3","Gene synonym":["C7orf1","CPE-R2","CPETR2","HRVP1","RVP1"],"Ensembl":"ENSG00000165215","Gene description":"Claudin 3","Uniprot":["O15551"],"Chromosome":"7","Position":"73768997-73770270","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Williams-Beuren syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"263.1","thyroid gland":"116.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal enterocytes":"2982.2","Endometrial ciliated cells":"1357.2","Enteroendocrine cells":"1248.1","Glandular and luminal cells":"1733.9","Intestinal goblet cells":"1898.0","Paneth cells":"2571.8","Proximal enterocytes":"3285.8","Undifferentiated cells":"1536.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"529.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"160.4"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Skin - Eccrine sweat gland cells","Stomach - Gastric enteroendocrine cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"1.5"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"9.7"},"Antibody":["HPA014361"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA014361":"AB_2668982"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.39e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"}},{"Gene":"CLDN34","Gene synonym":[],"Ensembl":"ENSG00000234469","Gene description":"Claudin 34","Uniprot":["H7C241"],"Chromosome":"X","Position":"9967358-9968352","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"1.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"14.0","Late spermatids":"7.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-5"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"}},{"Gene":"CLDN4","Gene synonym":["CPE-R","CPETR","CPETR1","hCPE-R","WBSCR8"],"Ensembl":"ENSG00000189143","Gene description":"Claudin 4","Uniprot":["O14493"],"Chromosome":"7","Position":"73799542-73832690","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["Cancer-related genes","Williams-Beuren syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"305.0","urinary bladder":"303.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"2383.2","Glandular and luminal cells":"2376.1","Ionocytes":"1671.8","Paneth cells":"2229.6","Proximal enterocytes":"1664.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"1.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"964.6"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Liver - Cholangiocyte","Lung - Alveolar cells type 2","Pancreas - Ductal cells","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002610"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002610":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.28e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.46e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"}},{"Gene":"CLDN5","Gene synonym":["AWAL","BEC1","CPETRL1","TMVCF"],"Ensembl":"ENSG00000184113","Gene description":"Claudin 5","Uniprot":["O00501"],"Chromosome":"22","Position":"19523024-19527545","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"439.7","breast":"420.9","lung":"398.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Adipocytes":"2811.5","Endothelial cells":"858.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"32.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"18.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"18.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Bone cancer":"7.1","Leukemia":"3.4","lung cancer":"2.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002607"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002607":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"}},{"Gene":"CLDN6","Gene synonym":[],"Ensembl":"ENSG00000184697","Gene description":"Claudin 6","Uniprot":["P56747"],"Chromosome":"16","Position":"3014712-3020071","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.1","pancreas":"1.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"41.3","Ductal cells":"22.5","Extravillous trophoblasts":"150.6","Fibroblasts":"34.4","Syncytiotrophoblasts":"38.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"73.6","testis cancer":"112.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"testis cancer":"328.9"},"RNA tissue cell type enrichment":["Pancreas - Ductal cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.42e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.78e-4"}},{"Gene":"CLDN7","Gene synonym":["CEPTRL2","CPETRL2","Hs.84359"],"Ensembl":"ENSG00000181885","Gene description":"Claudin 7","Uniprot":["O95471"],"Chromosome":"17","Position":"7259903-7263983","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"341.3","intestine":"341.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"1325.5","Intestinal goblet cells":"775.6","Paneth cells":"891.5","Proximal enterocytes":"1352.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Alveolar cells type 2","Pancreas - Ductal cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013063","HPA014703","HPA073662"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"CAB013063":null,"HPA014703":"AB_1846873","HPA073662":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.96e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.09e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"}},{"Gene":"CLDN8","Gene synonym":[],"Ensembl":"ENSG00000156284","Gene description":"Claudin 8","Uniprot":["P56748"],"Chromosome":"21","Position":"30214006-30216097","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"68.9","intestine":"50.8","kidney":"69.3","salivary gland":"40.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"196.9","Distal enterocytes":"86.8","Salivary duct cells":"37.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"31.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"16.7","prostate cancer":"8.9"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Intercalated cells","Lung - Respiratory ciliated cells","Skin - Eccrine sweat gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060605"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060605":"AB_2684331"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.32e-4"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"}},{"Gene":"CLDN9","Gene synonym":[],"Ensembl":"ENSG00000213937","Gene description":"Claudin 9","Uniprot":["O95484"],"Chromosome":"16","Position":"3012923-3014505","Protein class":["Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.8","pituitary gland":"25.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cholangiocytes":"15.4","Ductal cells":"8.7","Endometrial ciliated cells":"10.5","Respiratory ciliated cells":"17.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"10.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Ductal cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076613"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA076613":"AB_2686808"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.24e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.67e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"}},{"Gene":"CLDND1","Gene synonym":["C3orf4","Z38"],"Ensembl":"ENSG00000080822","Gene description":"Claudin domain containing 1","Uniprot":["Q9NY35"],"Chromosome":"3","Position":"98497912-98523066","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"1093.8","choroid plexus":"316.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"542.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029841"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA029841":"AB_10600658"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.84e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"}},{"Gene":"CLDND2","Gene synonym":["MGC33839"],"Ensembl":"ENSG00000160318","Gene description":"Claudin domain containing 2","Uniprot":["Q8NHS1"],"Chromosome":"19","Position":"51367098-51369003","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"44.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Early spermatids":"417.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056971"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA056971":"AB_2683294"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"}},{"Gene":"CLEC10A","Gene synonym":["CD301","CLECSF13","CLECSF14","HML","HML2"],"Ensembl":"ENSG00000132514","Gene description":"C-type lectin domain containing 10A","Uniprot":["Q8IUN9"],"Chromosome":"17","Position":"7074537-7080307","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Endocytosis","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"29.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Langerhans cells":"1026.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"myeloid DC":"465.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"465.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021937"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021937":"AB_1846905"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.26e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.24e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.22e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"}},{"Gene":"CLEC12A","Gene synonym":["CD371","CLL-1","DCAL-2","MICL"],"Ensembl":"ENSG00000172322","Gene description":"C-type lectin domain family 12 member A","Uniprot":["Q5QGZ9"],"Chromosome":"12","Position":"9951316-9995694","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"79.9","lymphoid tissue":"22.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"29.9","Hofbauer cells":"64.9","Kupffer cells":"99.4","Macrophages":"127.3","monocytes":"181.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"202.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"37","RNA blood lineage specific nTPM":{"dendritic cells":"72.6","granulocytes":"202.6","monocytes":"136.6"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Leukemia":"21.3"},"RNA tissue cell type enrichment":["Stomach - Macrophages"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"basal ganglia":"6.2"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048515"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048515":"AB_2680425"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.33e-4"}},{"Gene":"CLEC12B","Gene synonym":[],"Ensembl":"ENSG00000256660","Gene description":"C-type lectin domain family 12 member B","Uniprot":["Q2HXU8"],"Chromosome":"12","Position":"10010627-10018796","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"5.1","skin 1":"4.2","testis":"13.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Melanocytes":"146.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.3","Rhabdoid":"2.1"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-4"}},{"Gene":"CLEC14A","Gene synonym":["C14orf27"],"Ensembl":"ENSG00000176435","Gene description":"C-type lectin domain containing 14A","Uniprot":["Q86T13"],"Chromosome":"14","Position":"38254000-38256093","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Adipocytes":"384.2","Endothelial cells":"325.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"24","RNA cell line specific nTPM":{"Leukemia":"8.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039468","HPA048119"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4100000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Endoplasmic reticulum","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA039468":"AB_2676524","HPA048119":"AB_2680270"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.13e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"}},{"Gene":"CLEC17A","Gene synonym":["FLJ45910"],"Ensembl":"ENSG00000187912","Gene description":"C-type lectin domain containing 17A","Uniprot":["Q6ZS10"],"Chromosome":"19","Position":"14583084-14612035","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"6.6","lymphoid tissue":"18.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"21.7","Early spermatids":"4.3","Late spermatids":"11.5","Microglial cells":"2.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"memory B-cell":"21.5","naive B-cell":"43.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"B-cells":"43.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"lymphoma":"13.9"},"RNA tissue cell type enrichment":["Lung - B-cells","Prostate - T-cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"CLEC1A","Gene synonym":["CLEC1","MGC34328"],"Ensembl":"ENSG00000150048","Gene description":"C-type lectin domain family 1 member A","Uniprot":["Q8NC01"],"Chromosome":"12","Position":"10069554-10111627","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"50.2","placenta":"49.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"48.6","Cytotrophoblasts":"53.5","Endothelial cells":"35.3","Extravillous trophoblasts":"65.6","Syncytiotrophoblasts":"52.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"2.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"5.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"}},{"Gene":"CLEC1B","Gene synonym":["CLEC2"],"Ensembl":"ENSG00000165682","Gene description":"C-type lectin domain family 1 member B","Uniprot":["Q9P126"],"Chromosome":"12","Position":"9985642-10013424","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"liver":"65.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endothelial cells":"25.7","Fibroblasts":"106.8","Kupffer cells":"51.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"13.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"13.8","monocytes":"5.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"Leukemia":"4.0","Myeloma":"3.9","Rhabdoid":"3.3"},"RNA tissue cell type enrichment":["Liver - Sinusoid Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051108"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051108":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"}},{"Gene":"CLEC2A","Gene synonym":["INPE5792","KACL","PILAR","UNQ5792"],"Ensembl":"ENSG00000188393","Gene description":"C-type lectin domain family 2 member A","Uniprot":["Q6UVW9"],"Chromosome":"12","Position":"9898673-9932370","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"skin 1":"57.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"8.8","granulocytes":"6.5","Melanocytes":"3.5","Suprabasal keratinocytes":"18.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"1.1"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"2.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"Leukemia":"7.4"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048530","HPA072407"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA048530":"AB_2680429","HPA072407":"AB_2686518"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CLEC2D","Gene synonym":["CLAX","LLT1","OCIL"],"Ensembl":"ENSG00000069493","Gene description":"C-type lectin domain family 2 member D","Uniprot":["Q9UHP7"],"Chromosome":"12","Position":"9664969-9699553","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"53.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"94.6","Early spermatids":"79.1","NK-cells":"136.3","T-cells":"200.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"gdT-cell":"188.1","MAIT T-cell":"114.5","memory B-cell":"95.0","memory CD4 T-cell":"183.3","memory CD8 T-cell":"208.7","naive B-cell":"127.5","naive CD4 T-cell":"192.3","naive CD8 T-cell":"223.0","T-reg":"175.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"B-cells":"127.5","T-cells":"223.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"18.0","lymphoma":"53.3","Myeloma":"16.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Liver - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017649","HPA047584"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA017649":"AB_1846912","HPA047584":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.37e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.85e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.68e-7"}},{"Gene":"CLEC2L","Gene synonym":["FLJ32986"],"Ensembl":"ENSG00000236279","Gene description":"C-type lectin domain family 2 member L","Uniprot":["P0C7M8"],"Chromosome":"7","Position":"139523685-139544985","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"36.6","parathyroid gland":"14.2","retina":"10.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"50.9","Horizontal cells":"42.3","Inhibitory neurons":"48.5","Theca cells":"46.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"3.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"6.2"},"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045050"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045050":"AB_10965839"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"}},{"Gene":"CLEC4A","Gene synonym":["CD367","CLECSF6","DCIR","DDB27"],"Ensembl":"ENSG00000111729","Gene description":"C-type lectin domain family 4 member A","Uniprot":["Q9UMR7"],"Chromosome":"12","Position":"8123617-8138607","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"21.6","lymphoid tissue":"26.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hofbauer cells":"14.3","Kupffer cells":"37.4","Langerhans cells":"31.5","Macrophages":"35.9","monocytes":"33.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"226.8","classical monocyte":"331.7","intermediate monocyte":"198.1","myeloid DC":"327.4","neutrophil":"298.3","non-classical monocyte":"130.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"dendritic cells":"327.4","granulocytes":"298.3","monocytes":"331.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007842"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007842":"AB_1078534"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"}},{"Gene":"CLEC4C","Gene synonym":["BDCA2","CD303","CLECSF11","CLECSF7","DLEC","HECL"],"Ensembl":"ENSG00000198178","Gene description":"C-type lectin domain family 4 member C","Uniprot":["Q8WTT0"],"Chromosome":"12","Position":"7729383-7751605","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"5.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"23","RNA single cell type specific nTPM":{"dendritic cells":"197.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"plasmacytoid DC":"468.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"dendritic cells":"468.0"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029432"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029432":"AB_10601259"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-5"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"CLEC4D","Gene synonym":["CD368","CLECSF8","Dectin-3","MCL","Mpcl"],"Ensembl":"ENSG00000166527","Gene description":"C-type lectin domain family 4 member D","Uniprot":["Q8WXI8"],"Chromosome":"12","Position":"8509475-8522366","Protein class":["CD markers","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"bone marrow":"64.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Hofbauer cells":"8.1","Kupffer cells":"22.7","Macrophages":"10.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"50","RNA cancer specific FPKM":{"testis cancer":"11.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"17","RNA blood cell specific nTPM":{"classical monocyte":"57.1","neutrophil":"98.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"granulocytes":"98.7","monocytes":"57.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"testis cancer":"9.1"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Colon - Neutrophils","Heart muscle - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004906"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004906":"AB_1078535"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"}},{"Gene":"CLEC4E","Gene synonym":["CLECSF9","mincle"],"Ensembl":"ENSG00000166523","Gene description":"C-type lectin domain family 4 member E","Uniprot":["Q9ULY5"],"Chromosome":"12","Position":"8533305-8540905","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"75.7","lymphoid tissue":"52.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"40.0","Hofbauer cells":"53.7","Kupffer cells":"219.9","Macrophages":"111.5","monocytes":"111.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"6.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"classical monocyte":"128.8","neutrophil":"448.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"granulocytes":"448.8","monocytes":"128.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Kidney cancer":"34.2","ovarian cancer":"11.5"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2","Pancreas - Macrophages","Prostate - Macrophages","Skin - Macrophages","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004935"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004935":"AB_2667299"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"}},{"Gene":"CLEC4F","Gene synonym":["CLECSF13","FLJ39110","KCLR"],"Ensembl":"ENSG00000152672","Gene description":"C-type lectin domain family 4 member F","Uniprot":["Q8N1N0"],"Chromosome":"2","Position":"70808643-70820599","Protein class":["Predicted membrane proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"17.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"monocytes":"19.2","Rod photoreceptor cells":"9.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"intermediate monocyte":"6.0","non-classical monocyte":"4.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"monocytes":"6.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"5.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056101"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA056101":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"}},{"Gene":"CLEC4G","Gene synonym":["LSECtin","UNQ431"],"Ensembl":"ENSG00000182566","Gene description":"C-type lectin domain family 4 member G","Uniprot":["Q6UXB4"],"Chromosome":"19","Position":"7728958-7733906","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"14.9","liver":"53.3","lymphoid tissue":"15.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"2.0","Inhibitory neurons":"1.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"18.8","myeloid DC":"15.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"15.1","monocytes":"18.8"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Colon - Macrophages","Kidney - Macrophages","Liver - Sinusoid Endothelial cells","Skeletal muscle - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003789","HPA014044"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB003789":null,"HPA014044":"AB_1846916"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"}},{"Gene":"CLEC4M","Gene synonym":["CD209L","CD299","DC-SIGN2","DC-SIGNR","DCSIGNR","HP10347","LSIGN"],"Ensembl":"ENSG00000104938","Gene description":"C-type lectin domain family 4 member M","Uniprot":["Q9H2X3"],"Chromosome":"19","Position":"7763210-7769605","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Endocytosis","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"62.6","lymphoid tissue":"16.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Endothelial cells":"23.5","Fibroblasts":"42.6","Granulosa cells":"15.0","Kupffer cells":"22.8","Sertoli cells":"41.5","Theca cells":"24.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033689","CAB033691","HPA042661"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3400000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033689":"AB_831088","CAB033691":"AB_2081354","HPA042661":"AB_2678101"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"}},{"Gene":"CLEC5A","Gene synonym":["CLECSF5","MDL-1"],"Ensembl":"ENSG00000258227","Gene description":"C-type lectin domain containing 5A","Uniprot":["Q9NY25"],"Chromosome":"7","Position":"141927357-141947007","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"41.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hofbauer cells":"34.4","Langerhans cells":"94.9","Macrophages":"51.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"classical monocyte":"9.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"monocytes":"9.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"141","RNA cell line specific nTPM":{"Leukemia":"14.0"},"RNA tissue cell type enrichment":["Kidney - Macrophages","Prostate - Macrophages","Skin - Langerhans cells","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054137"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA054137":"AB_2732582"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.21e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"}},{"Gene":"CLEC6A","Gene synonym":["CLECSF10","dectin-2"],"Ensembl":"ENSG00000205846","Gene description":"C-type lectin domain containing 6A","Uniprot":["Q6EIG7"],"Chromosome":"12","Position":"8455962-8478330","Protein class":["Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"1.0","lymphoid tissue":"1.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"3.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"testis cancer":"1.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"5.4","myeloid DC":"2.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"2.2","monocytes":"5.4"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"}},{"Gene":"CLEC7A","Gene synonym":["CD369","CLECSF12","dectin-1","hDectin-1","SCARE2"],"Ensembl":"ENSG00000172243","Gene description":"C-type lectin domain containing 7A","Uniprot":["Q9BXN2"],"Chromosome":"12","Position":"10116777-10130258","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"84.0","lung":"30.9","lymphoid tissue":"44.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hofbauer cells":"188.6","Kupffer cells":"344.7","Langerhans cells":"338.1","Macrophages":"242.9","monocytes":"527.0","Schwann cells":"231.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"249.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Myeloma":"69.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Colon - Macrophages","Kidney - Macrophages","Pancreas - Macrophages","Skeletal muscle - Macrophages","Skin - T-cells","Stomach - Macrophages","Testis - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.31e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"}},{"Gene":"CLEC9A","Gene synonym":["CD370","DNGR-1","HEEE9341","UNQ9341"],"Ensembl":"ENSG00000197992","Gene description":"C-type lectin domain containing 9A","Uniprot":["Q6UXN8"],"Chromosome":"12","Position":"10030678-10066031","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"7.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Schwann cells":"246.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"testis cancer":"2.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"96","RNA blood cell specific nTPM":{"myeloid DC":"22.0","neutrophil":"7.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"96","RNA blood lineage specific nTPM":{"dendritic cells":"22.0","granulocytes":"7.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"21","RNA cell line specific nTPM":{"Leukemia":"2.4","Myeloma":"3.2"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"}},{"Gene":"CLECL1","Gene synonym":["DCAL1"],"Ensembl":"ENSG00000184293","Gene description":"C-type lectin like 1","Uniprot":["Q8IZS7"],"Chromosome":"12","Position":"9715860-9733299","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"9.9","lymphoid tissue":"31.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"95.2","dendritic cells":"66.3","granulocytes":"38.8","Hofbauer cells":"24.6","Langerhans cells":"82.8","Macrophages":"23.9","Plasma cells":"33.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"120.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"120.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"261","RNA cell line specific nTPM":{"Leukemia":"38.3","lymphoma":"86.1","Myeloma":"29.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063928"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Plasma membrane","Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"HPA063928":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"}},{"Gene":"CLGN","Gene synonym":[],"Ensembl":"ENSG00000153132","Gene description":"Calmegin","Uniprot":["O14967"],"Chromosome":"4","Position":"140388453-140427661","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"59.5","testis":"113.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"448.9","Early spermatids":"208.0","Endometrial ciliated cells":"100.8","Muller glia cells":"149.5","Prostatic glandular cells":"106.6","Spermatocytes":"400.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"19.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"34.7"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Heart muscle - Cardiomyocytes","Pancreas - Alpha cells","Prostate - Prostate glandular cells","Skin - Eccrine sweat gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020709","HPA048761","HPA058627"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB020709":null,"HPA048761":"AB_2680514","HPA058627":"AB_2683782"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"}},{"Gene":"CLIP4","Gene synonym":["FLJ21069","RSNL2"],"Ensembl":"ENSG00000115295","Gene description":"CAP-Gly domain containing linker protein family member 4","Uniprot":["Q8N3C7"],"Chromosome":"2","Position":"29097705-29189643","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"119.4","Inhibitory neurons":"139.8","Late spermatids":"132.6","Oligodendrocyte precursor cells":"124.7","Oligodendrocytes":"233.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"25.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043366","HPA056246"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA043366":"AB_10963051","HPA056246":"AB_2683078"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"}},{"Gene":"CLK4","Gene synonym":[],"Ensembl":"ENSG00000113240","Gene description":"CDC like kinase 4","Uniprot":["Q9HAZ1"],"Chromosome":"5","Position":"178602664-178630615","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"164.5","Late spermatids":"583.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043746"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA043746":"AB_2678650"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"}},{"Gene":"CLMN","Gene synonym":["FLJ12383","KIAA0500","KIAA1188"],"Ensembl":"ENSG00000165959","Gene description":"Calmin","Uniprot":["Q96JQ2"],"Chromosome":"14","Position":"95181940-95319908","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"67.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"325.6","Oligodendrocytes":"395.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012634"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA012634":"AB_1846973"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.68e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-3"}},{"Gene":"CLMP","Gene synonym":["ACAM","ASAM","FLJ22415"],"Ensembl":"ENSG00000166250","Gene description":"CXADR like membrane protein","Uniprot":["Q9H6B4"],"Chromosome":"11","Position":"123069872-123195248","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"63.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"76.2","Excitatory neurons":"26.1","Fibroblasts":"59.3","Inhibitory neurons":"31.3","Peritubular cells":"60.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Colon - Smooth muscle cells","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Pancreas - Fibroblasts","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"310000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"}},{"Gene":"CLN3","Gene synonym":["BTN1","BTS","JNCL"],"Ensembl":"ENSG00000188603","Gene description":"CLN3 lysosomal\/endosomal transmembrane protein, battenin","Uniprot":["Q13286"],"Chromosome":"16","Position":"28474111-28495575","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063280"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063280":"AB_2684975"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"}},{"Gene":"CLN5","Gene synonym":[],"Ensembl":"ENSG00000102805","Gene description":"CLN5 intracellular trafficking protein","Uniprot":["O75503"],"Chromosome":"13","Position":"76990660-77019143","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"155.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041788"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"470000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041788":"AB_10962726"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.52e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"}},{"Gene":"CLN6","Gene synonym":["FLJ20561","HsT18960","nclf"],"Ensembl":"ENSG00000128973","Gene description":"CLN6 transmembrane ER protein","Uniprot":["Q9NWW5"],"Chromosome":"15","Position":"68206992-68257211","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"110.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Lung - Macrophages","Stomach - Mitotic cells (Stomach)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066046","HPA066759"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoli","Vesicles"],"Antibody RRID":{"HPA066046":"AB_2685604","HPA066759":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"}},{"Gene":"CLN8","Gene synonym":["C8orf61","EPMR","FLJ39417","TLCD6"],"Ensembl":"ENSG00000182372","Gene description":"CLN8 transmembrane ER and ERGIC protein","Uniprot":["Q9UBY8"],"Chromosome":"8","Position":"1755778-1801711","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"357.8","Langerhans cells":"161.8","Syncytiotrophoblasts":"142.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"76.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"76.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.36e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"}},{"Gene":"CLPB","Gene synonym":["ANKCLB","FLJ13152","HSP78","SKD3"],"Ensembl":"ENSG00000162129","Gene description":"Caseinolytic mitochondrial matrix peptidase chaperone subunit B","Uniprot":["Q9H078"],"Chromosome":"11","Position":"72285495-72434680","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cataract","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"testis":"144.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Late spermatids":"5121.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"25.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"25.5","granulocytes":"7.7","monocytes":"15.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039005","HPA039006","HPA064571"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039005":"AB_2676305","HPA039006":"AB_10672767","HPA064571":"AB_2685290"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.36e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"}},{"Gene":"CLPTM1","Gene synonym":[],"Ensembl":"ENSG00000104853","Gene description":"CLPTM1 regulator of GABA type A receptor forward trafficking","Uniprot":["O96005"],"Chromosome":"19","Position":"44954585-44993341","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068767"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA068767":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"}},{"Gene":"CLPTM1L","Gene synonym":["CRR9","FLJ14400"],"Ensembl":"ENSG00000049656","Gene description":"CLPTM1 like","Uniprot":["Q96KA5"],"Chromosome":"5","Position":"1317752-1345099","Protein class":["Predicted membrane proteins"],"Biological process":["Apoptosis","Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"249.7","Plasma cells":"190.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014791"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA014791":"AB_1847250"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.75e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"}},{"Gene":"CLRN1","Gene synonym":["RP61","USH3","USH3A"],"Ensembl":"ENSG00000163646","Gene description":"Clarin 1","Uniprot":["P58418"],"Chromosome":"3","Position":"150926163-150972727","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hearing","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"adrenal gland":"4.9","retina":"12.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"24","RNA single cell type specific nTPM":{"Muller glia cells":"140.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CLRN2","Gene synonym":[],"Ensembl":"ENSG00000249581","Gene description":"Clarin 2","Uniprot":["A0PK11"],"Chromosome":"4","Position":"17515165-17527104","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042407"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042407":"AB_10806237"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CLRN3","Gene synonym":["MGC32871","TMEM12","USH3AL1"],"Ensembl":"ENSG00000180745","Gene description":"Clarin 3","Uniprot":["Q8NCR9"],"Chromosome":"10","Position":"127877841-127892941","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"89.0","kidney":"43.9","liver":"79.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"83.4","Enteroendocrine cells":"54.2","Hepatocytes":"40.9","Intestinal goblet cells":"79.0","Paneth cells":"78.3","Proximal enterocytes":"156.0","Proximal tubular cells":"55.8","Undifferentiated cells":"31.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"45.3","renal cancer":"30.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"colorectal cancer":"35.0","Gastric cancer":"22.7"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Pancreas - Ductal cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014482"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014482":"AB_2082885"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.98e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"}},{"Gene":"CLSTN1","Gene synonym":["CDHR12","CSTN1","KIAA0911"],"Ensembl":"ENSG00000171603","Gene description":"Calsyntenin 1","Uniprot":["O94985"],"Chromosome":"1","Position":"9728926-9823984","Protein class":["Cancer-related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"411.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012412","HPA077705"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"86000000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012412":"AB_1846981","HPA077705":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.10e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"}},{"Gene":"CLSTN2","Gene synonym":["CDHR13","CS2","CSTN2","FLJ39113"],"Ensembl":"ENSG00000158258","Gene description":"Calsyntenin 2","Uniprot":["Q9H4D0"],"Chromosome":"3","Position":"139935185-140577397","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adipose tissue":"18.2","brain":"26.7","ovary":"64.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"543.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"breast cancer":"15.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"20.6","testis cancer":"42.7"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031342","HPA061800"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA031342":"AB_10602800","HPA061800":"AB_2684615"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-5"}},{"Gene":"CLSTN3","Gene synonym":["CDHR14","CSTN3","KIAA0726"],"Ensembl":"ENSG00000139182","Gene description":"Calsyntenin 3","Uniprot":["Q9BQT9"],"Chromosome":"12","Position":"7129698-7158945","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"142.9","Excitatory neurons":"78.3","Inhibitory neurons":"58.9","Rod photoreceptor cells":"45.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"6.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1700000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.08e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.19e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.07e-4"}},{"Gene":"CLTCL1","Gene synonym":["CHC22","CLH22","CLTCL","CLTD"],"Ensembl":"ENSG00000070371","Gene description":"Clathrin heavy chain like 1","Uniprot":["P53675"],"Chromosome":"22","Position":"19179473-19291719","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skeletal muscle":"187.4","testis":"47.2","tongue":"61.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"13.3","Late spermatids":"19.7","Oligodendrocyte precursor cells":"12.0","Oligodendrocytes":"11.7","Skeletal myocytes":"15.8","Spermatocytes":"12.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"classical monocyte":"2.1","neutrophil":"5.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"granulocytes":"5.2","monocytes":"2.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075327","HPA075795"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2300000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA075327":null,"HPA075795":"AB_2686764"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"CLTRN","Gene synonym":["NX17","TMEM27"],"Ensembl":"ENSG00000147003","Gene description":"Collectrin, amino acid transport regulator","Uniprot":["Q9HBJ8"],"Chromosome":"X","Position":"15627318-15675012","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"kidney":"486.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Proximal tubular cells":"680.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"35","RNA cancer specific FPKM":{"renal cancer":"106.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048543"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Endoplasmic reticulum","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA048543":"AB_2680436"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.65e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.78e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"}},{"Gene":"CLYBL","Gene synonym":["CLB"],"Ensembl":"ENSG00000125246","Gene description":"Citramalyl-CoA lyase","Uniprot":["Q8N0X4"],"Chromosome":"13","Position":"99606669-99897134","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Lyase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"109.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"82.2","Distal tubular cells":"121.3","Hepatocytes":"113.1","Proximal tubular cells":"149.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039959","HPA040691"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7300","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039959":"AB_10793857","HPA040691":"AB_10794746"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.66e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"}},{"Gene":"CMKLR1","Gene synonym":["RVER1"],"Ensembl":"ENSG00000174600","Gene description":"Chemerin chemokine-like receptor 1","Uniprot":["Q99788"],"Chromosome":"12","Position":"108288044-108339317","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"34.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"18.9","Hofbauer cells":"29.2","Kupffer cells":"19.5","Macrophages":"37.3","Microglial cells":"38.3","monocytes":"15.8","NK-cells":"16.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"14.5","plasmacytoid DC":"18.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"dendritic cells":"18.1","monocytes":"14.5","T-cells":"7.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Macrophages","Heart muscle - Fibroblasts","Liver - Kupffer cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047865"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047865":"AB_2680191"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"}},{"Gene":"CMTM1","Gene synonym":["CKLFH","CKLFH1a","CKLFSF1"],"Ensembl":"ENSG00000089505","Gene description":"CKLF like MARVEL transmembrane domain containing 1","Uniprot":["Q8IZ96"],"Chromosome":"16","Position":"66566393-66579137","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Chemotaxis"],"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"testis":"31.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"54.2","Late spermatids":"112.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"8.7","eosinophil":"6.2","neutrophil":"7.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"8.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013801","HPA017136"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA013801":"AB_1846990","HPA017136":"AB_1846992"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.68e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"}},{"Gene":"CMTM2","Gene synonym":["CKLFSF2","FLJ25732","MGC39436"],"Ensembl":"ENSG00000140932","Gene description":"CKLF like MARVEL transmembrane domain containing 2","Uniprot":["Q8TAZ6"],"Chromosome":"16","Position":"66579448-66588275","Protein class":["Predicted membrane proteins"],"Biological process":["Chemotaxis"],"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"429","RNA tissue specific nTPM":{"testis":"648.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"56","RNA single cell type specific nTPM":{"Early spermatids":"3421.7","Late spermatids":"3443.2","Spermatocytes":"1129.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Lung - Neutrophil_2","Stomach - Neutrophils","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"CMTM3","Gene synonym":["BNAS2","CKLFSF3","FLJ31762"],"Ensembl":"ENSG00000140931","Gene description":"CKLF like MARVEL transmembrane domain containing 3","Uniprot":["Q96MX0"],"Chromosome":"16","Position":"66603874-66613892","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Chemotaxis"],"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"103.1","Extravillous trophoblasts":"263.3","Granulosa cells":"133.7","Hofbauer cells":"121.7","Sertoli cells":"110.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Heart muscle - Fibroblasts","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013870","HPA072695"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA013870":"AB_1847003","HPA072695":"AB_2732210"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.42e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.85e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"}},{"Gene":"CMTM4","Gene synonym":["CKLFSF4"],"Ensembl":"ENSG00000183723","Gene description":"CKLF like MARVEL transmembrane domain containing 4","Uniprot":["Q8IZR5"],"Chromosome":"16","Position":"66614750-66696743","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"45.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"80.2","Distal enterocytes":"75.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014704","HPA023890"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Golgi apparatus","Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014704":"AB_1847005","HPA023890":"AB_1847007"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.72e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"}},{"Gene":"CMTM5","Gene synonym":["CKLFSF5","FLJ37521"],"Ensembl":"ENSG00000166091","Gene description":"CKLF like MARVEL transmembrane domain containing 5","Uniprot":["Q96DZ9"],"Chromosome":"14","Position":"23376773-23379772","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Chemotaxis"],"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"182.4","choroid plexus":"49.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Melanocytes":"20.9","Muller glia cells":"28.1","Oligodendrocyte precursor cells":"19.7","Oligodendrocytes":"100.3","Schwann cells":"78.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"37","RNA cancer specific FPKM":{"glioma":"8.4","melanoma":"3.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"20.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"granulocytes":"20.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Brain cancer":"1.8","Leukemia":"6.8","skin cancer":"4.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Enteric glia cells","Skin - Smooth muscle cells","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052338"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"540000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA052338":"AB_2681793"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"}},{"Gene":"CMTM6","Gene synonym":["CKLFSF6","FLJ20396"],"Ensembl":"ENSG00000091317","Gene description":"CKLF like MARVEL transmembrane domain containing 6","Uniprot":["Q9NX76"],"Chromosome":"3","Position":"32481312-32502852","Protein class":["Predicted membrane proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"992.3","monocytes":"629.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Skeletal muscle - Endothelial cells","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026980","HPA063491"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA026980":"AB_10602801","HPA063491":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"}},{"Gene":"CMTM7","Gene synonym":["CKLFSF7","FLJ30992"],"Ensembl":"ENSG00000153551","Gene description":"CKLF like MARVEL transmembrane domain containing 7","Uniprot":["Q96FZ5"],"Chromosome":"3","Position":"32391698-32483067","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Chemotaxis"],"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"133.6","Kupffer cells":"102.6","Langerhans cells":"121.2","monocytes":"120.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077409"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA077409":"AB_2686838"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.00e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"}},{"Gene":"CMTM8","Gene synonym":["CKLFSF8"],"Ensembl":"ENSG00000170293","Gene description":"CKLF like MARVEL transmembrane domain containing 8","Uniprot":["Q8IZV2"],"Chromosome":"3","Position":"32238679-32370321","Protein class":["Predicted membrane proteins"],"Biological process":["Chemotaxis"],"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"47.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"108.8","Granulosa cells":"136.8","Syncytiotrophoblasts":"120.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Heart muscle - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055077","HPA073258"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA055077":"AB_2682691","HPA073258":"AB_2686591"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.80e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"}},{"Gene":"CMTR2","Gene synonym":["AFT","FLJ11171","FTSJD1","MTr2"],"Ensembl":"ENSG00000180917","Gene description":"Cap methyltransferase 2","Uniprot":["Q8IYT2"],"Chromosome":"16","Position":"71281389-71289715","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["mRNA capping","mRNA processing"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"94.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041700","HPA048265"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA041700":"AB_2677623","HPA048265":"AB_2680334"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.97e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"}},{"Gene":"CNDP2","Gene synonym":["CN2","CPGL","FLJ10830","HsT2298","PEPA"],"Ensembl":"ENSG00000133313","Gene description":"Carnosine dipeptidase 2","Uniprot":["Q96KP4"],"Chromosome":"18","Position":"74495816-74523454","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"335.1","Proximal enterocytes":"628.1","Proximal tubular cells":"440.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Breast glandular cells","Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026196","HPA036898","HPA036899"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2600000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB026196":null,"HPA036898":"AB_2675370","HPA036899":"AB_2675371"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.50e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"CNEP1R1","Gene synonym":["C16orf69","FLJ38101","NEP1-R1","TMEM188"],"Ensembl":"ENSG00000205423","Gene description":"CTD nuclear envelope phosphatase 1 regulatory subunit 1","Uniprot":["Q8N9A8"],"Chromosome":"16","Position":"50024410-50037088","Protein class":["Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"47.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042815","HPA077906"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042815":"AB_10794765","HPA077906":"AB_2686868"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"}},{"Gene":"CNGA1","Gene synonym":["CNCG","CNCG1","CNG1","RCNC1","RCNCa","RP49"],"Ensembl":"ENSG00000198515","Gene description":"Cyclic nucleotide gated channel subunit alpha 1","Uniprot":["P29973"],"Chromosome":"4","Position":"47935977-48016681","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"retina":"264.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"925.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"4.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"1.0"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076168"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA076168":"AB_2686781"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"}},{"Gene":"CNGA2","Gene synonym":["CNCA","CNCA1","CNG2","FLJ46312","OCNC1","OCNCa","OCNCALPHA"],"Ensembl":"ENSG00000183862","Gene description":"Cyclic nucleotide gated channel subunit alpha 2","Uniprot":["Q16280"],"Chromosome":"X","Position":"151738451-151745304","Protein class":["Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Olfaction","Sensory transduction","Transport"],"Molecular function":["Calmodulin-binding","Ion channel","Ligand-gated ion channel"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015065"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015065":"AB_1847034"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CNGA3","Gene synonym":["ACHM2","CCNC1","CCNCa","CNCG3","CNG3"],"Ensembl":"ENSG00000144191","Gene description":"Cyclic nucleotide gated channel subunit alpha 3","Uniprot":["Q16281"],"Chromosome":"2","Position":"98346188-98398601","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel"],"Disease involvement":["Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.7","intestine":"4.2","pituitary gland":"10.1","retina":"5.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"34.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"7.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Neuroblastoma":"2.5"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"basal ganglia":"1.8","hypothalamus":"1.9"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049378","CAB079025"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079025":null,"HPA049378":"AB_2732551"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"}},{"Gene":"CNGA4","Gene synonym":["CNCA2","CNG5","CNGB2","OCNC2","OCNCb"],"Ensembl":"ENSG00000132259","Gene description":"Cyclic nucleotide gated channel subunit alpha 4","Uniprot":["Q8IV77"],"Chromosome":"11","Position":"6234765-6244479","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Olfaction","Sensory transduction","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"17.3","testis":"6.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"8.9","Early spermatids":"4.7","Endometrial ciliated cells":"2.7","Excitatory neurons":"3.0","Inhibitory neurons":"2.5","Late spermatids":"4.5","Oligodendrocytes":"2.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"endometrial cancer":"2.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074128"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA074128":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.48e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"}},{"Gene":"CNGB1","Gene synonym":["CNCG2","CNCG3L","CNGB1B","GAR1","GARP","RCNC2","RCNCb","RP45"],"Ensembl":"ENSG00000070729","Gene description":"Cyclic nucleotide gated channel subunit beta 1","Uniprot":["Q14028"],"Chromosome":"16","Position":"57882340-57971128","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Olfaction","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"retina":"600.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"353.3","Rod photoreceptor cells":"1052.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"head and neck cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"12.3"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Ductal cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"4.5"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060355"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA060355":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"}},{"Gene":"CNGB3","Gene synonym":["ACHM1","ACHM3","RMCH"],"Ensembl":"ENSG00000170289","Gene description":"Cyclic nucleotide gated channel subunit beta 3","Uniprot":["Q9NQW8"],"Chromosome":"8","Position":"86553977-86743675","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel"],"Disease involvement":["Disease variant","Stargardt disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"4.1","retina":"13.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"253.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057244"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057244":"AB_2683380"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"}},{"Gene":"CNIH1","Gene synonym":["CNIH","CNIL","TGAM77"],"Ensembl":"ENSG00000100528","Gene description":"Cornichon family AMPA receptor auxiliary protein 1","Uniprot":["O95406"],"Chromosome":"14","Position":"54423561-54441391","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["ER-Golgi transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002544"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA002544":"AB_2081856"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.95e-4"}},{"Gene":"CNIH2","Gene synonym":["CNIH-2","Cnil","MGC50896"],"Ensembl":"ENSG00000174871","Gene description":"Cornichon family AMPA receptor auxiliary protein 2","Uniprot":["Q6PI25"],"Chromosome":"11","Position":"66278175-66285301","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"270.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"69.3","Enteroendocrine cells":"15.9","Excitatory neurons":"17.4","Late spermatids":"39.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"20.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"10.5"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Lung - Respiratory ciliated cells","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.18e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"}},{"Gene":"CNIH3","Gene synonym":["CNIH-3","FLJ38993"],"Ensembl":"ENSG00000143786","Gene description":"Cornichon family AMPA receptor auxiliary protein 3","Uniprot":["Q8TBE1"],"Chromosome":"1","Position":"224434660-224740554","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"13.5","pancreas":"8.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"63.3","Distal tubular cells":"31.1","Excitatory neurons":"60.2","Inhibitory neurons":"46.4","Late spermatids":"39.9","Oligodendrocyte precursor cells":"65.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"6.0","melanoma":"7.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"18.0","thyroid cancer":"17.9"},"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"}},{"Gene":"CNIH4","Gene synonym":["HSPC163"],"Ensembl":"ENSG00000143771","Gene description":"Cornichon family AMPA receptor auxiliary protein 4","Uniprot":["Q9P003"],"Chromosome":"1","Position":"224356858-224379459","Protein class":["Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"314.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044268"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044268":"AB_10965330"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.61e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.27e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"}},{"Gene":"CNKSR2","Gene synonym":["CNK2","KIAA0902","KSR2"],"Ensembl":"ENSG00000149970","Gene description":"Connector enhancer of kinase suppressor of Ras 2","Uniprot":["Q8WXI2"],"Chromosome":"X","Position":"21372801-21654695","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"22.6","retina":"17.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"108.2","Excitatory neurons":"490.6","Horizontal cells":"116.0","Inhibitory neurons":"140.0","Oligodendrocyte precursor cells":"89.5","Rod photoreceptor cells":"218.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Fibroblast_1","Skin - Fibroblast_2","Testis - Spermatogonia","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001502"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA001502":"AB_1078542"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"}},{"Gene":"CNMD","Gene synonym":["BRICD3","CHM-I","CHM1","LECT1","MYETS1"],"Ensembl":"ENSG00000136110","Gene description":"Chondromodulin","Uniprot":["O75829"],"Chromosome":"13","Position":"52703264-52739820","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Chondrogenesis","Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.9","retina":"8.4","salivary gland":"6.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Muller glia cells":"85.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"1.5","lung cancer":"6.0","testis cancer":"5.8","thyroid cancer":"4.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"1.5","testis cancer":"1.3"},"RNA tissue cell type enrichment":["Pancreas - Beta cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010510"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9500","Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010510":"AB_10602021"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"CNN2","Gene synonym":[],"Ensembl":"ENSG00000064666","Gene description":"Calponin 2","Uniprot":["Q99439"],"Chromosome":"19","Position":"1026586-1039068","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding","Calmodulin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049095"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8400000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Actin filaments"],"Antibody RRID":{"HPA049095":"AB_2680627"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.70e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"}},{"Gene":"CNNM1","Gene synonym":["ACDP1"],"Ensembl":"ENSG00000119946","Gene description":"Cyclin and CBS domain divalent metal cation transport mediator 1","Uniprot":["Q9NRU3"],"Chromosome":"10","Position":"99329356-99394330","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"16.7","testis":"9.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"34.5","Early spermatids":"98.5","Excitatory neurons":"68.9","Horizontal cells":"35.2","Inhibitory neurons":"87.5","Late spermatids":"98.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040408"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA040408":"AB_10793963"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"}},{"Gene":"CNNM2","Gene synonym":["ACDP2"],"Ensembl":"ENSG00000148842","Gene description":"Cyclin and CBS domain divalent metal cation transport mediator 2","Uniprot":["Q9H8M5"],"Chromosome":"10","Position":"102918294-103090222","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"37.9","parathyroid gland":"31.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"58.2","Excitatory neurons":"111.0","Inhibitory neurons":"143.6","Oligodendrocyte precursor cells":"88.6","Oligodendrocytes":"87.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"NK-cell":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"NK-cells":"1.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059954","HPA071631"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059954":"AB_2684177","HPA071631":"AB_2686427"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.39e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"}},{"Gene":"CNNM3","Gene synonym":["ACDP3"],"Ensembl":"ENSG00000168763","Gene description":"Cyclin and CBS domain divalent metal cation transport mediator 3","Uniprot":["Q8NE01"],"Chromosome":"2","Position":"96816245-96835382","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016711"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA016711":"AB_1847394"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"}},{"Gene":"CNNM4","Gene synonym":["ACDP4","KIAA1592"],"Ensembl":"ENSG00000158158","Gene description":"Cyclin and CBS domain divalent metal cation transport mediator 4","Uniprot":["Q6P4Q7"],"Chromosome":"2","Position":"96760902-96811874","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Biomineralization","Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"38.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"96.5","Distal enterocytes":"65.3","Rod photoreceptor cells":"49.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 1","Skeletal muscle - Skeletal myocytes","Stomach - Gastric mucous cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017732"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA017732":"AB_1847395"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.14e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.75e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"CNOT1","Gene synonym":["AD-005","CDC39","KIAA1007","NOT1","NOT1H"],"Ensembl":"ENSG00000125107","Gene description":"CCR4-NOT transcription complex subunit 1","Uniprot":["A5YKK6"],"Chromosome":"16","Position":"58519951-58629885","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["RNA-mediated gene silencing","Transcription","Transcription regulation","Translation regulation"],"Molecular function":["Developmental protein","Repressor"],"Disease involvement":["Autism spectrum disorder","Disease variant","Holoprosencephaly","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029844","HPA046577","HPA049664"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029844":null,"HPA046577":"AB_2679706","HPA049664":"AB_2680844"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"}},{"Gene":"CNOT9","Gene synonym":["CAF40","CT129","RCD1","RCD1+","RQCD1"],"Ensembl":"ENSG00000144580","Gene description":"CCR4-NOT transcription complex subunit 9","Uniprot":["Q92600"],"Chromosome":"2","Position":"218568580-218597080","Protein class":["Predicted intracellular proteins"],"Biological process":["RNA-mediated gene silencing","Transcription","Transcription regulation","Translation regulation"],"Molecular function":["Activator","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046622"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytoplasmic bodies"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Cytoplasmic bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA046622":"AB_10962694"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.41e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.69e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"}},{"Gene":"CNPPD1","Gene synonym":["C2orf24","CGI-57"],"Ensembl":"ENSG00000115649","Gene description":"Cyclin Pas1\/PHO80 domain containing 1","Uniprot":["Q9BV87"],"Chromosome":"2","Position":"219171897-219178106","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049303"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049303":"AB_2680703"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.04e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.62e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"}},{"Gene":"CNR1","Gene synonym":["CANN6","CB-R","CB1","CB1A","CB1K5","CNR"],"Ensembl":"ENSG00000118432","Gene description":"Cannabinoid receptor 1","Uniprot":["P21554"],"Chromosome":"6","Position":"88139864-88166359","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"23.0","brain":"25.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"20.6","Excitatory neurons":"44.0","Inhibitory neurons":"196.1","Sertoli cells":"49.8","Smooth muscle cells":"21.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"glioma":"12.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"18.0","lymphoma":"24.3"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042256","HPA069945"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA042256":"AB_2677917","HPA069945":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"}},{"Gene":"CNR2","Gene synonym":["CB2"],"Ensembl":"ENSG00000188822","Gene description":"Cannabinoid receptor 2","Uniprot":["P34972"],"Chromosome":"1","Position":"23870515-23913362","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Inflammatory response"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"3.4","lymphoid tissue":"8.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"35.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"testis cancer":"2.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"49.3","eosinophil":"35.1","memory B-cell":"29.6","naive B-cell":"27.9","NK-cell":"19.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"29.6","granulocytes":"49.3","NK-cells":"19.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Leukemia":"2.9","lymphoma":"5.6"},"RNA tissue cell type enrichment":["Lung - B-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009719"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009719":"AB_2082784"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"}},{"Gene":"CNST","Gene synonym":["C1orf71","FLJ32001","PPP1R64"],"Ensembl":"ENSG00000162852","Gene description":"Consortin, connexin sorting protein","Uniprot":["Q6PJW8"],"Chromosome":"1","Position":"246566444-246668595","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007225","HPA007226"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"480000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA007225":"AB_1848869","HPA007226":"AB_2667782"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"}},{"Gene":"CNTD1","Gene synonym":["CNTD","FLJ40137"],"Ensembl":"ENSG00000176563","Gene description":"Cyclin N-terminal domain containing 1","Uniprot":["Q8N815"],"Chromosome":"17","Position":"42798800-42811587","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Meiosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"testis":"42.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"71.7","Late spermatids":"127.3","Spermatocytes":"138.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072363"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA072363":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-4"}},{"Gene":"CNTFR","Gene synonym":[],"Ensembl":"ENSG00000122756","Gene description":"Ciliary neurotrophic factor receptor","Uniprot":["P26992"],"Chromosome":"9","Position":"34551432-34590140","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"94.1","skeletal muscle":"129.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"55.4","Muller glia cells":"78.5","Paneth cells":"37.5","Sertoli cells":"24.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"22.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Neuroblastoma":"94.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Lung - Fibroblast_2","Pancreas - Fibroblasts","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025310"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025310":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"CNTN6","Gene synonym":["NB-3"],"Ensembl":"ENSG00000134115","Gene description":"Contactin 6","Uniprot":["Q9UQ52"],"Chromosome":"3","Position":"1092658-1404217","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion","Notch signaling pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.0","thyroid gland":"9.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"125.8","Inhibitory neurons":"74.0","Oligodendrocyte precursor cells":"50.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"renal cancer":"2.7","thyroid cancer":"3.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"1.7","thyroid cancer":"1.8"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016645"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4700000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016645":"AB_1847149"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"}},{"Gene":"CNTNAP1","Gene synonym":["Caspr","CNTNAP","NRXN4","p190"],"Ensembl":"ENSG00000108797","Gene description":"Contactin associated protein 1","Uniprot":["P78357"],"Chromosome":"17","Position":"42682531-42699993","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"46.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"23.2","Endometrial stromal cells":"17.8","Excitatory neurons":"44.9","Horizontal cells":"27.6","Inhibitory neurons":"36.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"10.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011772"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA011772":"AB_1079541"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.16e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-3"}},{"Gene":"CNTNAP2","Gene synonym":["Caspr2","KIAA0868","NRXN4"],"Ensembl":"ENSG00000174469","Gene description":"Contactin associated protein 2","Uniprot":["Q9UHC6"],"Chromosome":"7","Position":"146116002-148420998","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Autism","Autism spectrum disorder","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"20.7","retina":"14.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"3333.9","Inhibitory neurons":"6694.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"10.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"2.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"25","RNA blood lineage specific nTPM":{"B-cells":"2.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"5.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Liver - Hepatocytes","Prostate - Prostate glandular cells","Skin - Outer root sheath cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002739"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002739":"AB_1078545"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"}},{"Gene":"CNTNAP3","Gene synonym":["CASPR3","CNTNAP3A","FLJ14195","KIAA1714"],"Ensembl":"ENSG00000106714","Gene description":"Contactin associated protein family member 3","Uniprot":["Q9BZ76"],"Chromosome":"9","Position":"39072767-39288315","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Inhibitory neurons":"101.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"20","RNA blood cell specific nTPM":{"neutrophil":"7.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"74","RNA blood lineage specific nTPM":{"granulocytes":"7.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047731"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047731":"AB_2680137"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"}},{"Gene":"CNTNAP3B","Gene synonym":[],"Ensembl":"ENSG00000154529","Gene description":"Contactin associated protein family member 3B","Uniprot":["Q96NU0"],"Chromosome":"9","Position":"41890314-42129510","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"62.4","Astrocytes":"33.5","Endothelial cells":"38.4","Excitatory neurons":"34.0","Inhibitory neurons":"158.9","Microglial cells":"32.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"neutrophil":"3.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"38","RNA blood lineage specific nTPM":{"granulocytes":"3.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047731"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047731":"AB_2680137"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-4"}},{"Gene":"CNTNAP4","Gene synonym":["CASPR4","KIAA1763"],"Ensembl":"ENSG00000152910","Gene description":"Contactin associated protein family member 4","Uniprot":["Q9C0A0"],"Chromosome":"16","Position":"76277278-76560757","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"brain":"121.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Inhibitory neurons":"318.0","Oligodendrocytes":"1085.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"2.8","Neuroblastoma":"2.3","Rhabdoid":"2.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031859"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2800000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031859":"AB_10601360"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"CNTNAP5","Gene synonym":["caspr5","FLJ31966"],"Ensembl":"ENSG00000155052","Gene description":"Contactin associated protein family member 5","Uniprot":["Q8WYK1"],"Chromosome":"2","Position":"124025287-124915287","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"7.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"56","RNA single cell type specific nTPM":{"Excitatory neurons":"545.5","Inhibitory neurons":"884.8","Oligodendrocyte precursor cells":"727.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"1.3"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Intercalated cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069095","HPA069356"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA069095":"AB_2686083","HPA069356":"AB_2686127"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"}},{"Gene":"COA1","Gene synonym":["C7orf44","FLJ10803","MITRAC15"],"Ensembl":"ENSG00000106603","Gene description":"Cytochrome c oxidase assembly factor 1 homolog","Uniprot":["Q9GZY4"],"Chromosome":"7","Position":"43608456-43729717","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011944"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA011944":"AB_1848671"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.84e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"}},{"Gene":"COA3","Gene synonym":["CCDC56","COX25","HSPC009","MITRAC12"],"Ensembl":"ENSG00000183978","Gene description":"Cytochrome c oxidase assembly factor 3","Uniprot":["Q9Y2R0"],"Chromosome":"17","Position":"42795147-42798704","Protein class":["Disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"569.1","Proximal tubular cells":"685.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031966","HPA071122"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA031966":"AB_10602115","HPA071122":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.40e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.93e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.62e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"}},{"Gene":"COCH","Gene synonym":["COCH-5B2","DFNA31","DFNA9"],"Ensembl":"ENSG00000100473","Gene description":"Cochlin","Uniprot":["O43405"],"Chromosome":"14","Position":"30874514-30895065","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"pancreas":"502.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"35.6","Horizontal cells":"33.3","Inhibitory neurons":"23.6","Spermatocytes":"29.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"71.3"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"memory B-cell":"38.3","naive B-cell":"17.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"B-cells":"38.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"50.8"},"Antibody":["HPA065086"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA065086":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"}},{"Gene":"COL17A1","Gene synonym":["BP180","BPAG2"],"Ensembl":"ENSG00000065618","Gene description":"Collagen type XVII alpha 1 chain","Uniprot":["Q9UMD9"],"Chromosome":"10","Position":"104031286-104085880","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Epidermolysis bullosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"580.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"677.3","Basal respiratory cells":"125.9","Basal squamous epithelial cells":"191.5","Distal enterocytes":"118.0","Salivary duct cells":"116.5","Suprabasal keratinocytes":"156.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"head and neck cancer":"227.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"430.4"},"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Colon - Colon enterocytes","Prostate - Prostate basal glandular cells","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"cerebellum":"1.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043673","HPA052963"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"32000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA043673":"AB_10960893","HPA052963":"AB_2681999"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.38e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.86e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"}},{"Gene":"COL25A1","Gene synonym":[],"Ensembl":"ENSG00000188517","Gene description":"Collagen type XXV alpha 1 chain","Uniprot":["Q9BXS0"],"Chromosome":"4","Position":"108808725-109302752","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Heparin-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"30.0","retina":"24.7","testis":"19.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"95.8","Inhibitory neurons":"268.0","Late spermatids":"53.8","Rod photoreceptor cells":"94.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"14.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029107"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA029107":"AB_10600802"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"}},{"Gene":"COL27A1","Gene synonym":["FLJ11895","KIAA1870","MGC11337"],"Ensembl":"ENSG00000196739","Gene description":"Collagen type XXVII alpha 1 chain","Uniprot":["Q8IZC6"],"Chromosome":"9","Position":"114155537-114312511","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"93.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"52.0","Extravillous trophoblasts":"90.8","Melanocytes":"41.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"29.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"19","RNA pig brain regional specific nTPM":{"cerebellum":"71.0"},"Antibody":["HPA021884","HPA048471"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021884":"AB_2670857","HPA048471":"AB_2680407"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.11e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"}},{"Gene":"COLEC12","Gene synonym":["CL-P1","SCARA4","SRCL"],"Ensembl":"ENSG00000158270","Gene description":"Collectin subfamily member 12","Uniprot":["Q5KU26"],"Chromosome":"18","Position":"316737-500722","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"31.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"143.0","Hofbauer cells":"132.0","Microglial cells":"239.0","Syncytiotrophoblasts":"97.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"14.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"14.4"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Liver - Vascular Endothelial cells","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047917","HPA071056"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"580000","Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA047917":"AB_2680208","HPA071056":"AB_2686338"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.10e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"}},{"Gene":"COMT","Gene synonym":[],"Ensembl":"ENSG00000093010","Gene description":"Catechol-O-methyltransferase","Uniprot":["P21964"],"Chromosome":"22","Position":"19941371-19969975","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Catecholamine metabolism","Lipid metabolism","Neurotransmitter degradation"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":["FDA approved drug targets","Schizophrenia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"905.2","Syncytiotrophoblasts":"638.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001169","CAB011233"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"43000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"CAB011233":null,"HPA001169":"AB_1078402"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.68e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.67e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.76e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"}},{"Gene":"COMTD1","Gene synonym":["FLJ23841"],"Ensembl":"ENSG00000165644","Gene description":"Catechol-O-methyltransferase domain containing 1","Uniprot":["Q86VU5"],"Chromosome":"10","Position":"75233641-75236030","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"128.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"262.1","Proximal enterocytes":"438.1","Squamous epithelial cells":"286.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042165"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA042165":"AB_10794042"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.88e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"}},{"Gene":"COP1","Gene synonym":["CFAP78","FAP78","FLJ10416","RFWD2","RNF200"],"Ensembl":"ENSG00000143207","Gene description":"COP1 E3 ubiquitin ligase","Uniprot":["Q8NHY2"],"Chromosome":"1","Position":"175944831-176207286","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"221.5","Inhibitory neurons":"174.0","Microglial cells":"126.8","Oligodendrocyte precursor cells":"125.2","Oligodendrocytes":"152.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.96e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"}},{"Gene":"COPE","Gene synonym":["epsilon-COP"],"Ensembl":"ENSG00000105669","Gene description":"COPI coat complex subunit epsilon","Uniprot":["O14579"],"Chromosome":"19","Position":"18899514-18919387","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034345","HPA041605","HPA043576"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"66000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB034345":"AB_2081323","HPA041605":"AB_2677578","HPA043576":"AB_2678563"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.41e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"}},{"Gene":"COPS3","Gene synonym":["CSN3","SGN3"],"Ensembl":"ENSG00000141030","Gene description":"COP9 signalosome subunit 3","Uniprot":["Q9UNS2"],"Chromosome":"17","Position":"17246616-17281273","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"247.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021997","HPA050557"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA021997":"AB_1847152","HPA050557":"AB_2681176"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.56e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.65e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-3"}},{"Gene":"COPS4","Gene synonym":["CSN4"],"Ensembl":"ENSG00000138663","Gene description":"COP9 signalosome subunit 4","Uniprot":["Q9BT78"],"Chromosome":"4","Position":"83034447-83075818","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"162.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036894","HPA042828"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036894":"AB_10670929","HPA042828":"AB_2678191"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.14e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"}},{"Gene":"COPZ1","Gene synonym":["CGI-120","COPZ"],"Ensembl":"ENSG00000111481","Gene description":"COPI coat complex subunit zeta 1","Uniprot":["P61923"],"Chromosome":"12","Position":"54301202-54351846","Protein class":["Predicted intracellular proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"70000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.84e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.40e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"}},{"Gene":"COQ2","Gene synonym":["CL640","FLJ26072"],"Ensembl":"ENSG00000173085","Gene description":"Coenzyme Q2, polyprenyltransferase","Uniprot":["Q96H96"],"Chromosome":"4","Position":"83261536-83284914","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Isoprene biosynthesis","Ubiquinone biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Parkinsonism","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"37.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056599","HPA068727"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA056599":"AB_2683184","HPA068727":"AB_2686022"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"}},{"Gene":"COQ5","Gene synonym":["MGC4767"],"Ensembl":"ENSG00000110871","Gene description":"Coenzyme Q5, methyltransferase","Uniprot":["Q5HYK3"],"Chromosome":"12","Position":"120503279-120534434","Protein class":["Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Ubiquinone biosynthesis"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049487"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA049487":"AB_2680789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"}},{"Gene":"CORIN","Gene synonym":["ATC2","CRN","Lrp4","PRSC","TMPRSS10"],"Ensembl":"ENSG00000145244","Gene description":"Corin, serine peptidase","Uniprot":["Q9Y5Q5"],"Chromosome":"4","Position":"47593999-47838106","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"heart muscle":"56.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cardiomyocytes":"71.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Uterine cancer":"1.1"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"2.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070941"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Plasma membrane","Actin filaments"],"Secretome location":"Intracellular and membrane","CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear bodies","Actin filaments"],"Antibody RRID":{"HPA070941":"AB_2686324"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"}},{"Gene":"COX10","Gene synonym":[],"Ensembl":"ENSG00000006695","Gene description":"Cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10","Uniprot":["Q12887"],"Chromosome":"17","Position":"14069490-14231736","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Heme biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Leigh syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"44.5","tongue":"44.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"133.0","Late spermatids":"79.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032005","HPA032006"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA032005":"AB_10603560","HPA032006":"AB_10670554"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.32e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.73e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"}},{"Gene":"COX11","Gene synonym":["COX11P"],"Ensembl":"ENSG00000166260","Gene description":"Cytochrome c oxidase copper chaperone COX11","Uniprot":["Q9Y6N1"],"Chromosome":"17","Position":"54951902-54968703","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"143.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044020"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044020":"AB_2678777"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.30e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"}},{"Gene":"COX15","Gene synonym":["CEMCOX2"],"Ensembl":"ENSG00000014919","Gene description":"Cytochrome c oxidase assembly homolog COX15","Uniprot":["Q7KZN9"],"Chromosome":"10","Position":"99710868-99732127","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Leigh syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037727","HPA037728","HPA066096"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA037727":"AB_10672391","HPA037728":"AB_10672463","HPA066096":"AB_2685616"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"}},{"Gene":"COX17","Gene synonym":[],"Ensembl":"ENSG00000138495","Gene description":"Cytochrome c oxidase copper chaperone COX17","Uniprot":["Q14061"],"Chromosome":"3","Position":"119654513-119677454","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"893.9","Distal tubular cells":"824.1","Hepatocytes":"932.8","Proximal tubular cells":"832.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042226","HPA048158"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA042226":"AB_2677911","HPA048158":"AB_2680292"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"}},{"Gene":"COX18","Gene synonym":["FLJ38991"],"Ensembl":"ENSG00000163626","Gene description":"Cytochrome c oxidase assembly factor COX18","Uniprot":["Q8N8Q8"],"Chromosome":"4","Position":"73052362-73069755","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046772","HPA049489"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046772":"AB_2679799","HPA049489":"AB_2680791"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.31e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.22e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"}},{"Gene":"COX20","Gene synonym":["FAM36A","FLJ43269"],"Ensembl":"ENSG00000203667","Gene description":"Cytochrome c oxidase assembly factor COX20","Uniprot":["Q5RI15"],"Chromosome":"1","Position":"244835616-244845057","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"491.8","Distal tubular cells":"497.6","Proximal tubular cells":"522.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043617","HPA045490"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA043617":"AB_10965694","HPA045490":"AB_10962869"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-3"}},{"Gene":"COX4I1","Gene synonym":["COX4","COX4-1"],"Ensembl":"ENSG00000131143","Gene description":"Cytochrome c oxidase subunit 4I1","Uniprot":["P13073"],"Chromosome":"16","Position":"85798633-85807068","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"4840.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002485","CAB004080"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB004080":"AB_2085427","HPA002485":"AB_1078559"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"}},{"Gene":"COX4I2","Gene synonym":["COX4-2","COX4B","COX4L2","COXIV-2","dJ857M17.2"],"Ensembl":"ENSG00000131055","Gene description":"Cytochrome c oxidase subunit 4I2","Uniprot":["Q96KJ9"],"Chromosome":"20","Position":"31637912-31645006","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"49.1","placenta":"115.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Adipocytes":"50.2","Sertoli cells":"157.6","Smooth muscle cells":"178.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"3.2","Neuroblastoma":"1.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.04e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.78e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"}},{"Gene":"COX6A1","Gene synonym":["COX6A"],"Ensembl":"ENSG00000111775","Gene description":"Cytochrome c oxidase subunit 6A1","Uniprot":["P12074"],"Chromosome":"12","Position":"120438090-120440737","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Charcot-Marie-Tooth disease","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"1996.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062394"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"85000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA062394":"AB_2684749"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.50e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"}},{"Gene":"COX6A2","Gene synonym":[],"Ensembl":"ENSG00000156885","Gene description":"Cytochrome c oxidase subunit 6A2","Uniprot":["Q02221"],"Chromosome":"16","Position":"31427731-31428360","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"46","RNA tissue specific nTPM":{"heart muscle":"3905.3","skeletal muscle":"6742.0","tongue":"2096.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"67","RNA single cell type specific nTPM":{"Cardiomyocytes":"6922.8","Skeletal myocytes":"2853.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"head and neck cancer":"9.3","liver cancer":"2.9","prostate cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"150","RNA blood cell specific nTPM":{"NK-cell":"15.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"150","RNA blood lineage specific nTPM":{"NK-cells":"15.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"1.0"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"COX6C","Gene synonym":[],"Ensembl":"ENSG00000164919","Gene description":"Cytochrome c oxidase subunit 6C","Uniprot":["P09669"],"Chromosome":"8","Position":"99873200-99893707","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"2810.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Prostate - Smooth muscle cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014295","CAB016244"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB016244":"AB_2085703","HPA014295":"AB_2668966"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-3"}},{"Gene":"COX7A1","Gene synonym":["COX7A","COX7AH"],"Ensembl":"ENSG00000161281","Gene description":"Cytochrome c oxidase subunit 7A1","Uniprot":["P24310"],"Chromosome":"19","Position":"36150922-36152449","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"heart muscle":"2260.5","skeletal muscle":"6947.0","tongue":"4960.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"25","RNA single cell type specific nTPM":{"Cardiomyocytes":"24900.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"27.3"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"COX7A2","Gene synonym":["COX7AL","COXVIIa-L"],"Ensembl":"ENSG00000112695","Gene description":"Cytochrome c oxidase subunit 7A2","Uniprot":[],"Chromosome":"6","Position":"75237675-75250323","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"3291.3","Early spermatids":"4259.0","Late spermatids":"3915.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"}},{"Gene":"COX7A2L","Gene synonym":["COX7AR","COX7RP","EB1","SIG81"],"Ensembl":"ENSG00000115944","Gene description":"Cytochrome c oxidase subunit 7A2 like","Uniprot":["O14548"],"Chromosome":"2","Position":"42333546-42425088","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059124","CAB073545"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB073545":null,"HPA059124":"AB_2683912"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.13e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"COX7B","Gene synonym":[],"Ensembl":"ENSG00000131174","Gene description":"Cytochrome c oxidase subunit 7B","Uniprot":["P24311"],"Chromosome":"X","Position":"77899440-77907376","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"1122.9","tongue":"756.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"3378.1","Distal tubular cells":"2273.2","Proximal tubular cells":"1962.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058041"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058041":"AB_2683587"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.80e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.43e-4"}},{"Gene":"COX7B2","Gene synonym":[],"Ensembl":"ENSG00000170516","Gene description":"Cytochrome c oxidase subunit 7B2","Uniprot":["Q8TF08"],"Chromosome":"4","Position":"46734827-46909245","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"70","RNA tissue specific nTPM":{"testis":"85.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"595.6","Late spermatids":"213.8","Spermatocytes":"338.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"7.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"14.8","thyroid cancer":"17.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"COX7C","Gene synonym":[],"Ensembl":"ENSG00000127184","Gene description":"Cytochrome c oxidase subunit 7C","Uniprot":["P15954"],"Chromosome":"5","Position":"86617928-86620962","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"2380.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"4911.8","Distal tubular cells":"5516.7","Proximal tubular cells":"6080.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046647"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"39000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046647":"AB_2679736"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.23e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"}},{"Gene":"COX8A","Gene synonym":["COX","COX8","COX8-2","COX8L","VIII","VIII-L"],"Ensembl":"ENSG00000176340","Gene description":"Cytochrome c oxidase subunit 8A","Uniprot":["P10176"],"Chromosome":"11","Position":"63974620-63976543","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"1795.5","Distal tubular cells":"2347.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055942"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055942":"AB_2682979"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.51e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"}},{"Gene":"COX8C","Gene synonym":["COX8-3"],"Ensembl":"ENSG00000187581","Gene description":"Cytochrome c oxidase subunit 8C","Uniprot":["Q7Z4L0"],"Chromosome":"14","Position":"93347182-93348356","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"51","RNA tissue specific nTPM":{"testis":"76.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"1887.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"ovarian cancer":"2.9","testis cancer":"6.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003127"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003127":"AB_1078560"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"}},{"Gene":"CPA5","Gene synonym":[],"Ensembl":"ENSG00000158525","Gene description":"Carboxypeptidase A5","Uniprot":["Q8WXQ8"],"Chromosome":"7","Position":"130344816-130368730","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"testis":"33.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"25","RNA single cell type specific nTPM":{"Early spermatids":"80.6","Late spermatids":"143.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory CD4 T-cell":"16.8","naive CD8 T-cell":"42.5","T-reg":"56.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"102","RNA blood lineage specific nTPM":{"T-cells":"56.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"29","RNA cell line specific nTPM":{"Sarcoma":"28.6"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020322"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA020322":"AB_10960562"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"}},{"Gene":"CPAMD8","Gene synonym":["K-CAP","KIAA1283","VIP"],"Ensembl":"ENSG00000160111","Gene description":"C3 and PZP like alpha-2-macroglobulin domain containing 8","Uniprot":["Q8IZJ3"],"Chromosome":"19","Position":"16892951-17026815","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.7","prostate":"34.1","seminal vesicle":"36.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"47.7","Collecting duct cells":"19.7","Leydig cells":"30.6","Prostatic glandular cells":"50.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"9.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"7.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"spinal cord":"5.6"},"Antibody":["HPA031327","HPA031328","HPA031329","HPA031330"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Focal adhesion sites"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA031327":"AB_2673829","HPA031328":"AB_2673830","HPA031329":null,"HPA031330":"AB_10603788"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"}},{"Gene":"CPD","Gene synonym":["GP180"],"Ensembl":"ENSG00000108582","Gene description":"Carboxypeptidase D","Uniprot":["O75976"],"Chromosome":"17","Position":"30378927-30469989","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ionocytes":"184.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"25.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052796"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1700000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA052796":"AB_2681953"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"}},{"Gene":"CPEB1","Gene synonym":["CPEB","FLJ13203"],"Ensembl":"ENSG00000214575","Gene description":"Cytoplasmic polyadenylation element binding protein 1","Uniprot":["Q9BZB8"],"Chromosome":"15","Position":"82543201-82648861","Protein class":["Predicted intracellular proteins"],"Biological process":["mRNA processing","Translation regulation"],"Molecular function":["Activator","Repressor","Ribonucleoprotein","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"33.6","testis":"32.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"69.0","Inhibitory neurons":"43.3","Oligodendrocytes":"185.5","Spermatocytes":"36.3","Spermatogonia":"65.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"testis cancer":"14.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD8 T-cell":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Liver - Hepatic stellate cells","Prostate - Fibroblasts","Testis - Spermatogonia","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040396"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA040396":"AB_2676960"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-4"}},{"Gene":"CPLANE1","Gene synonym":["C5orf42","FLJ13231","Hug","JBTS17"],"Ensembl":"ENSG00000197603","Gene description":"Ciliogenesis and planar polarity effector 1","Uniprot":["Q9H799"],"Chromosome":"5","Position":"37106228-37249376","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Joubert syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"171.7","Inhibitory neurons":"162.7","Oligodendrocyte precursor cells":"122.3","Oligodendrocytes":"119.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"22.8"},"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036775","HPA036776"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036775":"AB_10669914","HPA036776":"AB_2675308"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"}},{"Gene":"CPM","Gene synonym":[],"Ensembl":"ENSG00000135678","Gene description":"Carboxypeptidase M","Uniprot":["P14384"],"Chromosome":"12","Position":"68842197-68971570","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"156.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"224.7","Glandular and luminal cells":"230.3","granulocytes":"310.5","Macrophages":"272.9","Sertoli cells":"320.6","Syncytiotrophoblasts":"222.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"21.0","intermediate monocyte":"14.5","myeloid DC":"16.6","non-classical monocyte":"7.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"16.6","monocytes":"21.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Pancreas - Macrophages","Skin - Keratinocyte (granular)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002657","HPA077243"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7100000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA002657":"AB_1078398","HPA077243":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.00e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"CPNE2","Gene synonym":["CPN2"],"Ensembl":"ENSG00000140848","Gene description":"Copine 2","Uniprot":["Q96FN4"],"Chromosome":"16","Position":"57092583-57148369","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"87.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"76.9","Oligodendrocytes":"81.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Endothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041132"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041132":"AB_2677316"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"}},{"Gene":"CPNE5","Gene synonym":["COPN5","CPN5","KIAA1599"],"Ensembl":"ENSG00000124772","Gene description":"Copine 5","Uniprot":["Q9HCH3"],"Chromosome":"6","Position":"36740775-36839444","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"62.4","heart muscle":"92.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"33.3","Cardiomyocytes":"35.6","Excitatory neurons":"34.6","Horizontal cells":"41.0","Oligodendrocyte precursor cells":"35.1","Plasma cells":"125.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"11.3"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"62.4"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"80","RNA blood cell specific nTPM":{"memory B-cell":"51.6","naive B-cell":"26.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"105","RNA blood lineage specific nTPM":{"B-cells":"51.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"18.1","Myeloma":"29.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Prostate - Fibroblasts","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"103.3"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"135.5"},"Antibody":["HPA031369"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA031369":"AB_10601801"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.87e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.00e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"}},{"Gene":"CPNE7","Gene synonym":[],"Ensembl":"ENSG00000178773","Gene description":"Copine 7","Uniprot":["Q9UBL6"],"Chromosome":"16","Position":"89575758-89597246","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"28.0","epididymis":"19.3","pituitary gland":"14.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"10.2","Collecting duct cells":"15.8","Excitatory neurons":"9.2","Horizontal cells":"13.5","Inhibitory neurons":"8.9","Spermatogonia":"10.6","T-cells":"9.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"11.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"4.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"4.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043359"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043359":"AB_10794884"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.52e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.22e-4"}},{"Gene":"CPO","Gene synonym":[],"Ensembl":"ENSG00000144410","Gene description":"Carboxypeptidase O","Uniprot":["Q8IVL8"],"Chromosome":"2","Position":"206939518-206969474","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"intestine":"111.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Proximal enterocytes":"349.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"30","RNA blood cell specific nTPM":{"basophil":"12.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"84","RNA blood lineage specific nTPM":{"granulocytes":"12.0"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"}},{"Gene":"CPOX","Gene synonym":["CPO","CPX","HCP"],"Ensembl":"ENSG00000080819","Gene description":"Coproporphyrinogen oxidase","Uniprot":["P36551"],"Chromosome":"3","Position":"98579446-98593648","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Heme biosynthesis","Porphyrin biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Erythroid cells":"238.4","Extravillous trophoblasts":"80.0","Oligodendrocytes":"93.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015736","HPA054448"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA015736":"AB_1847194","HPA054448":"AB_2682490"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"}},{"Gene":"CPPED1","Gene synonym":["CSTP1","FLJ11151"],"Ensembl":"ENSG00000103381","Gene description":"Calcineurin like phosphoesterase domain containing 1","Uniprot":["Q9BRF8"],"Chromosome":"16","Position":"12659799-12803887","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"104.5","monocytes":"171.4","Syncytiotrophoblasts":"155.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"674.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"28","RNA blood lineage specific nTPM":{"dendritic cells":"168.5","granulocytes":"674.2","monocytes":"320.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040938","HPA041970"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"470000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA040938":"AB_10673443","HPA041970":"AB_2677774"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.72e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.62e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"}},{"Gene":"CPSF4","Gene synonym":["CPSF30","NAR"],"Ensembl":"ENSG00000160917","Gene description":"Cleavage and polyadenylation specific factor 4","Uniprot":["O95639"],"Chromosome":"7","Position":"99438922-99457373","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","mRNA processing"],"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"58.7","Syncytiotrophoblasts":"50.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049094","HPA066470"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA049094":"AB_2680626","HPA066470":"AB_2685672"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.87e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.68e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"}},{"Gene":"CPSF7","Gene synonym":["CFIM59","FLJ12529"],"Ensembl":"ENSG00000149532","Gene description":"Cleavage and polyadenylation specific factor 7","Uniprot":["Q8N684"],"Chromosome":"11","Position":"61402641-61430031","Protein class":["Predicted intracellular proteins"],"Biological process":["mRNA processing"],"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041094"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA041094":"AB_10794187"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.83e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"}},{"Gene":"CPT1A","Gene synonym":["CPT1","CPT1-L","L-CPT1"],"Ensembl":"ENSG00000110090","Gene description":"Carnitine palmitoyltransferase 1A","Uniprot":["P50416"],"Chromosome":"11","Position":"68754620-68844410","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Transport"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"110.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008835"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"45000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA008835":"AB_1078563"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.84e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.67e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"}},{"Gene":"CPT1B","Gene synonym":["CPT1-M","M-CPT1"],"Ensembl":"ENSG00000205560","Gene description":"Carnitine palmitoyltransferase 1B","Uniprot":["Q92523"],"Chromosome":"22","Position":"50568861-50578465","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Transport"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"heart muscle":"242.7","skeletal muscle":"144.5","testis":"80.7","tongue":"228.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"14.2","Early spermatids":"31.0","Late spermatids":"81.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079265"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA079265":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-5"}},{"Gene":"CPT1C","Gene synonym":["CATL1","CPT1P","CPTIC","FLJ23809"],"Ensembl":"ENSG00000169169","Gene description":"Carnitine palmitoyltransferase 1C","Uniprot":["Q8TCG5"],"Chromosome":"19","Position":"49690898-49713731","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"19.2","pituitary gland":"28.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"35.8","Excitatory neurons":"33.5","Horizontal cells":"27.6","Inhibitory neurons":"27.5","Late spermatids":"30.9","Oligodendrocyte precursor cells":"20.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"9.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"39.4","Rhabdoid":"49.2"},"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014529","HPA063621"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA014529":"AB_1847206","HPA063621":"AB_2732706"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.84e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-3"}},{"Gene":"CR1","Gene synonym":["CD35","KN"],"Ensembl":"ENSG00000203710","Gene description":"Complement C3b\/C4b receptor 1 (Knops blood group)","Uniprot":["P17927"],"Chromosome":"1","Position":"207496147-207641765","Protein class":["Blood group antigen proteins","CD markers","Plasma proteins","Predicted membrane proteins"],"Biological process":["Complement pathway","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Blood group antigen","Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"13.2","lymphoid tissue":"27.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"41.1","Erythroid cells":"17.2","Hofbauer cells":"17.1","Kupffer cells":"35.6","Macrophages":"45.8","monocytes":"18.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"53.7","eosinophil":"17.2","neutrophil":"15.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"granulocytes":"53.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"3.5","lymphoma":"1.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Kidney - Podocytes","Lung - Neutrophil_2","Prostate - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002491","CAB016271","HPA042455","HPA043579","HPA049348"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"33000000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002491":"AB_563553","CAB016271":"AB_627040","HPA042455":"AB_2678006","HPA043579":"AB_2678564","HPA049348":"AB_2680723"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-3"}},{"Gene":"CR2","Gene synonym":["C3DR","CD21"],"Ensembl":"ENSG00000117322","Gene description":"Complement C3d receptor 2","Uniprot":["P20023"],"Chromosome":"1","Position":"207454230-207489895","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Complement pathway","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"lymphoid tissue":"174.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"44.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"7.1","stomach cancer":"5.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"memory B-cell":"17.5","naive B-cell":"20.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"B-cells":"20.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"8.3","lymphoma":"16.8","Myeloma":"9.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002659","HPA052942","HPA060715"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002659":null,"HPA052942":"AB_2681994","HPA060715":"AB_2684349"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.90e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"}},{"Gene":"CRB1","Gene synonym":["LCA8","RP12"],"Ensembl":"ENSG00000134376","Gene description":"Crumbs cell polarity complex component 1","Uniprot":["P82279"],"Chromosome":"1","Position":"197268204-197478455","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Leber congenital amaurosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"21.3","retina":"74.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"454.9","Cone photoreceptor cells":"118.9","Inhibitory neurons":"126.9","Oligodendrocyte precursor cells":"268.1","Oligodendrocytes":"99.7","Rod photoreceptor cells":"152.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"glioma":"2.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"28","RNA blood cell specific nTPM":{"basophil":"7.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"28","RNA blood lineage specific nTPM":{"granulocytes":"7.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"cervical cancer":"6.3","Sarcoma":"4.8"},"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061250","HPA063127"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA061250":"AB_2684458","HPA063127":"AB_2684944"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"}},{"Gene":"CRB2","Gene synonym":["FLJ16786","FLJ38464"],"Ensembl":"ENSG00000148204","Gene description":"Crumbs cell polarity complex component 2","Uniprot":["Q5IJ48"],"Chromosome":"9","Position":"123356170-123380324","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Gastrulation","Sensory transduction","Vision"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"24.9","choroid plexus":"14.1","retina":"8.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"39.2","Bipolar cells":"37.4","Cone photoreceptor cells":"63.8","Oligodendrocytes":"25.4","Rod photoreceptor cells":"108.8","Thymic epithelial cells":"27.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"9.4","ovarian cancer":"5.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"4.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Podocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043674"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043674":"AB_10962974"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"}},{"Gene":"CRB3","Gene synonym":["MGC17303"],"Ensembl":"ENSG00000130545","Gene description":"Crumbs cell polarity complex component 3","Uniprot":["Q9BUF7"],"Chromosome":"19","Position":"6463777-6467221","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"54.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"145.3","Exocrine glandular cells":"137.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"9.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"B-cells":"3.1","T-cells":"9.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Lung - Alveolar cells type 2","Stomach - Gastric mucous cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013835"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA013835":"AB_1847214"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.54e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.06e-5"}},{"Gene":"CREB3","Gene synonym":["Luman","LZIP","sLZIP"],"Ensembl":"ENSG00000107175","Gene description":"CAMP responsive element binding protein 3","Uniprot":["O43889"],"Chromosome":"9","Position":"35732598-35736999","Protein class":["Predicted membrane proteins","Transcription factors"],"Biological process":["Chemotaxis","Host-virus interaction","Transcription","Transcription regulation","Unfolded protein response"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"434.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030978"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA030978":"AB_2673683"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.57e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.40e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"}},{"Gene":"CREB3L1","Gene synonym":["OASIS"],"Ensembl":"ENSG00000157613","Gene description":"CAMP responsive element binding protein 3 like 1","Uniprot":["Q96BA8"],"Chromosome":"11","Position":"46277662-46321409","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation","Unfolded protein response"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"133.9","salivary gland":"83.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"91.2","Glandular and luminal cells":"108.8","Intestinal goblet cells":"272.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"87.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Lung - Alveolar cells type 2","Skin - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024069","CAB026151","HPA062116"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB026151":null,"HPA024069":"AB_1854750","HPA062116":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.92e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.97e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.59e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"}},{"Gene":"CREB3L2","Gene synonym":["BBF2H7","TCAG_1951439"],"Ensembl":"ENSG00000182158","Gene description":"CAMP responsive element binding protein 3 like 2","Uniprot":["Q70SY1"],"Chromosome":"7","Position":"137874979-138002086","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation","Unfolded protein response"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"225.4","Plasma cells":"187.5","Syncytiotrophoblasts":"166.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Testis - Peritubular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015068","HPA015534"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA015068":"AB_1847224","HPA015534":"AB_2669210"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"}},{"Gene":"CREB3L3","Gene synonym":["CREB-H","CREBH"],"Ensembl":"ENSG00000060566","Gene description":"CAMP responsive element binding protein 3 like 3","Uniprot":["Q68CJ9"],"Chromosome":"19","Position":"4153631-4173054","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation","Unfolded protein response"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"71","RNA tissue specific nTPM":{"intestine":"257.2","liver":"415.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"383.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"liver cancer":"91.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"11.6","liver cancer":"25.1","pancreatic cancer":"9.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040671","HPA056228"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"32000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040671":"AB_2677072","HPA056228":"AB_2683072"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.53e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"}},{"Gene":"CREB3L4","Gene synonym":["AIbZIP","ATCE1","CREB3","CREB4","hJAL"],"Ensembl":"ENSG00000143578","Gene description":"CAMP responsive element binding protein 3 like 4","Uniprot":["Q8TEY5"],"Chromosome":"1","Position":"153967534-153974361","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation","Unfolded protein response"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"106.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"54.1","Intestinal goblet cells":"61.5","Prostatic glandular cells":"144.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"breast cancer":"47.8","endometrial cancer":"28.7","prostate cancer":"109.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"106.5"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038122"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA038122":"AB_10669516"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.21e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"}},{"Gene":"CRELD1","Gene synonym":["AVSD2","CIRRIN"],"Ensembl":"ENSG00000163703","Gene description":"Cysteine rich with EGF like domains 1","Uniprot":["Q96HD1"],"Chromosome":"3","Position":"9933816-9945406","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"42.1","Excitatory neurons":"37.5","Inhibitory neurons":"36.2","Oligodendrocytes":"20.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026964"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA026964":"AB_10602210"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.07e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"}},{"Gene":"CRHR1","Gene synonym":["CRF-R","CRF1","CRHR"],"Ensembl":"ENSG00000120088","Gene description":"Corticotropin releasing hormone receptor 1","Uniprot":["P34998"],"Chromosome":"17","Position":"45784280-45835828","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"10.4","pituitary gland":"22.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Bipolar cells":"1.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"10.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"1.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025251"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025251":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"}},{"Gene":"CRHR2","Gene synonym":["CRF-RB","CRF2","HM-CRF"],"Ensembl":"ENSG00000106113","Gene description":"Corticotropin releasing hormone receptor 2","Uniprot":["Q13324"],"Chromosome":"7","Position":"30651942-30700129","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.0","choroid plexus":"21.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"8.1","Horizontal cells":"11.5","Inhibitory neurons":"4.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"thyroid cancer":"5.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"8.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073345"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA073345":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"}},{"Gene":"CRIM1","Gene synonym":["S52"],"Ensembl":"ENSG00000150938","Gene description":"Cysteine rich transmembrane BMP regulator 1","Uniprot":["Q9NZV1"],"Chromosome":"2","Position":"36355778-36551135","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"163.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"244.9","Syncytiotrophoblasts":"165.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"2.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Skin - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000556"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000556":"AB_1078567"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.51e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"}},{"Gene":"CRISP2","Gene synonym":["CRISP-2","CT36","GAPDL5","TPX1"],"Ensembl":"ENSG00000124490","Gene description":"Cysteine rich secretory protein 2","Uniprot":["P16562"],"Chromosome":"6","Position":"49692358-49713590","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"testis":"505.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"22575.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"1.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Lung - Respiratory ciliated cells","Pancreas - Ductal cells","Skin - Eccrine sweat gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031248"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"820000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031248":"AB_10602211"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CRISP3","Gene synonym":["Aeg2","CRISP-3","CRS3","dJ442L6.3","SGP28"],"Ensembl":"ENSG00000096006","Gene description":"Cysteine rich secretory protein 3","Uniprot":["P54108"],"Chromosome":"6","Position":"49727376-49744437","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"fallopian tube":"1203.8","salivary gland":"2310.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Glandular and luminal cells":"618.0","Mucus glandular cells":"906.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"breast cancer":"31.9","pancreatic cancer":"59.8","prostate cancer":"85.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"neutrophil":"2.5","non-classical monocyte":"1.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"granulocytes":"2.5","monocytes":"1.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"16.4","prostate cancer":"49.0"},"RNA tissue cell type enrichment":["Lung - Neutrophil_1","Pancreas - Ductal cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054392"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"420000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054392":"AB_2682472"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"}},{"Gene":"CRK","Gene synonym":[],"Ensembl":"ENSG00000167193","Gene description":"CRK proto-oncogene, adaptor protein","Uniprot":["P46108"],"Chromosome":"17","Position":"1420689-1463162","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010485","HPA068087"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"400000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010485":"AB_2085043","HPA068087":"AB_2685950"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"}},{"Gene":"CRLF2","Gene synonym":["CRL2","TSLPR"],"Ensembl":"ENSG00000205755","Gene description":"Cytokine receptor like factor 2","Uniprot":["Q9HC73"],"Chromosome":"X","Position":"1187549-1212723","Protein class":["Cancer-related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1.8","gallbladder":"1.3","lymphoid tissue":"1.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"3.7","granulocytes":"17.2","Langerhans cells":"9.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"1.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"plasmacytoid DC":"1.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"dendritic cells":"1.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"7.6","Myeloma":"5.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Colon - Mast cells","Lung - Mast cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075272"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA075272":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"}},{"Gene":"CRLS1","Gene synonym":["C20orf155","CLS1","dJ967N21.6","GCD10"],"Ensembl":"ENSG00000088766","Gene description":"Cardiolipin synthase 1","Uniprot":["Q9UJA2"],"Chromosome":"20","Position":"6006093-6040053","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"169.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"36.5","Gastric mucus-secreting cells":"38.8","Oligodendrocyte precursor cells":"38.0","Thymic epithelial cells":"35.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.02e-4"}},{"Gene":"CROT","Gene synonym":["COT"],"Ensembl":"ENSG00000005469","Gene description":"Carnitine O-octanoyltransferase","Uniprot":["Q9UKG9"],"Chromosome":"7","Position":"87345664-87399794","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Transport"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"104.9","Cytotrophoblasts":"133.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019052","HPA019364","HPA019365"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA019052":"AB_1847172","HPA019364":"AB_1847173","HPA019365":"AB_1847174"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.55e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.02e-4"}},{"Gene":"CRTAC1","Gene synonym":["ASPIC1","CEP-68","FLJ10320"],"Ensembl":"ENSG00000095713","Gene description":"Cartilage acidic protein 1","Uniprot":["Q9NQ79"],"Chromosome":"10","Position":"97865000-98030828","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"45.6","fallopian tube":"38.2","lung":"50.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"120.3","Basal prostatic cells":"68.6","Horizontal cells":"28.2","Inhibitory neurons":"62.4","Oligodendrocyte precursor cells":"52.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"43.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"6.6"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Liver - Vascular Endothelial cells","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008175"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"550000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008175":"AB_1847254"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.51e-4"}},{"Gene":"CRTAM","Gene synonym":["CD355"],"Ensembl":"ENSG00000109943","Gene description":"Cytotoxic and regulatory T cell molecule","Uniprot":["O95727"],"Chromosome":"11","Position":"122838500-122872643","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Cell adhesion","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"38.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"14.2","Macrophages":"10.9","monocytes":"13.5","NK-cells":"55.4","T-cells":"50.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"9","RNA brain regional specific nTPM":{"cerebellum":"38.2"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"54.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"NK-cells":"54.0","T-cells":"33.3"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Liver - T-cells","Prostate - T-cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"44","RNA mouse brain regional specific nTPM":{"cerebellum":"102.6"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"cerebellum":"25.7"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6800000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"}},{"Gene":"CRTC1","Gene synonym":["FLJ14027","KIAA0616","MECT1","TORC1"],"Ensembl":"ENSG00000105662","Gene description":"CREB regulated transcription coactivator 1","Uniprot":["Q6UUV9"],"Chromosome":"19","Position":"18683678-18782333","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"38.0","Excitatory neurons":"36.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"203","RNA brain regional specific nTPM":{"amygdala":"14.2","basal ganglia":"11.4","cerebellum":"27.1","cerebral cortex":"24.3","hippocampal formation":"24.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022035","HPA063619"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA022035":"AB_1847255","HPA063619":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.80e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.83e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"}},{"Gene":"CRYAB","Gene synonym":["CRYA2","HSPB5"],"Ensembl":"ENSG00000109846","Gene description":"Crystallin alpha B","Uniprot":["P02511"],"Chromosome":"11","Position":"111908564-111923722","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone","Eye lens protein"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Cataract","Disease variant","Myofibrillar myopathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5623.2","heart muscle":"10683.1","skeletal muscle":"6972.0","tongue":"9406.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"7252.6","Proximal tubular cells":"7143.2","Schwann cells":"1889.6","Skeletal myocytes":"4399.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"426.4","renal cancer":"575.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"329.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002053","CAB040560","HPA057100"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002053":"AB_442024","CAB040560":null,"HPA057100":"AB_2683337"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.90e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-5"}},{"Gene":"CSF1","Gene synonym":["M-CSF","MCSF","MGC31930"],"Ensembl":"ENSG00000184371","Gene description":"Colony stimulating factor 1","Uniprot":["P09603"],"Chromosome":"1","Position":"109910242-109930992","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Cytokine","Growth factor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"41.8","Fibroblasts":"56.6","granulocytes":"93.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"basophil":"13.2","eosinophil":"22.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"granulocytes":"22.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076624"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":270000,"Blood concentration - Conc. blood MS [pg\/L]":"22000000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA076624":"AB_2686810"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.25e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.00e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"}},{"Gene":"CSF1R","Gene synonym":["C-FMS","CD115","CSFR","FMS"],"Ensembl":"ENSG00000182578","Gene description":"Colony stimulating factor 1 receptor","Uniprot":["P07333"],"Chromosome":"5","Position":"150053291-150113372","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Neurodegeneration","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"113.3","placenta":"103.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"116.5","Hofbauer cells":"330.9","Kupffer cells":"139.9","Langerhans cells":"99.2","Macrophages":"223.6","Microglial cells":"131.3","monocytes":"181.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"444.6","non-classical monocyte":"646.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"646.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"10.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Colon - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Langerhans cells","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008970","HPA012323"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB008970":null,"HPA012323":"AB_1848977"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.92e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"}},{"Gene":"CSF2RA","Gene synonym":["alphaGMR","CD116","CSF2R"],"Ensembl":"ENSG00000198223","Gene description":"Colony stimulating factor 2 receptor subunit alpha","Uniprot":["P15509"],"Chromosome":"X","Position":"1268800-1310381","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"64.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"246.2","Extravillous trophoblasts":"131.8","Langerhans cells":"711.1","Schwann cells":"142.6","Syncytiotrophoblasts":"349.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"320.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"30","RNA blood lineage specific nTPM":{"dendritic cells":"170.7","granulocytes":"320.2","monocytes":"161.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Pancreas - Macrophages","Skeletal muscle - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016148"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016148":"AB_626868"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.38e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.81e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.53e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"}},{"Gene":"CSF2RB","Gene synonym":["betaGMR","CD131","IL3RB","IL5RB"],"Ensembl":"ENSG00000100368","Gene description":"Colony stimulating factor 2 receptor subunit beta","Uniprot":["P32927"],"Chromosome":"22","Position":"36913628-36940439","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"54.5","lymphoid tissue":"65.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"117.3","Extravillous trophoblasts":"43.6","granulocytes":"81.5","Kupffer cells":"41.4","Langerhans cells":"74.7","Late spermatids":"41.5","Macrophages":"35.8","Plasma cells":"43.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"238.1","neutrophil":"76.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"granulocytes":"238.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"62","RNA cell line specific nTPM":{"Leukemia":"44.6","lymphoma":"18.9","Myeloma":"14.3"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078677"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA078677":"AB_2732389"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.47e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"}},{"Gene":"CSF3R","Gene synonym":["CD114","GCSFR"],"Ensembl":"ENSG00000119535","Gene description":"Colony stimulating factor 3 receptor","Uniprot":["Q99062"],"Chromosome":"1","Position":"36466043-36483278","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"bone marrow":"379.7","lung":"136.7","lymphoid tissue":"375.6","placenta":"105.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cytotrophoblasts":"399.6","Syncytiotrophoblasts":"1372.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"1962.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"1962.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"Leukemia":"48.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Neutrophils","Colon - Neutrophils","Heart muscle - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2","Skeletal muscle - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017116","HPA048086"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB017116":null,"HPA048086":"AB_2680257"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.72e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.79e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"}},{"Gene":"CSGALNACT2","Gene synonym":["GALNACT-2","GALNACT2","MGC40204","PRO0082"],"Ensembl":"ENSG00000169826","Gene description":"Chondroitin sulfate N-acetylgalactosaminyltransferase 2","Uniprot":["Q8N6G5"],"Chromosome":"10","Position":"43138445-43185302","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"133.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"144.0","Macrophages":"88.7","monocytes":"209.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031540"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA031540":"AB_10599943"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.53e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"}},{"Gene":"CSMD1","Gene synonym":["KIAA1890","PPP1R24"],"Ensembl":"ENSG00000183117","Gene description":"CUB and Sushi multiple domains 1","Uniprot":["Q96PZ7"],"Chromosome":"8","Position":"2935353-4994972","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"10.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Excitatory neurons":"4795.2","Inhibitory neurons":"3819.9","Oligodendrocyte precursor cells":"4330.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"10.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Skin - Smooth muscle cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074707"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA074707":"AB_2686707"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"}},{"Gene":"CSMD2","Gene synonym":["KIAA1884"],"Ensembl":"ENSG00000121904","Gene description":"CUB and Sushi multiple domains 2","Uniprot":["Q7Z408"],"Chromosome":"1","Position":"33513999-34165842","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"9.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"156.6","Inhibitory neurons":"145.3","Oligodendrocyte precursor cells":"301.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"5.6"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"}},{"Gene":"CSMD3","Gene synonym":[],"Ensembl":"ENSG00000164796","Gene description":"CUB and Sushi multiple domains 3","Uniprot":["Q7Z407"],"Chromosome":"8","Position":"112222928-113436939","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"6.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Excitatory neurons":"902.5","Inhibitory neurons":"846.2","Oligodendrocyte precursor cells":"1686.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029007","HPA029008"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA029007":"AB_10601802","HPA029008":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"}},{"Gene":"CSNK1A1","Gene synonym":["CK1","CK1a","CK1alpha","CKIa","CKIalpha"],"Ensembl":"ENSG00000113712","Gene description":"Casein kinase 1 alpha 1","Uniprot":["P48729"],"Chromosome":"5","Position":"149492982-149551471","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis","Wnt signaling pathway"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016680","HPA051334"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB016680":"AB_1614518","HPA051334":"AB_2681446"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.15e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.79e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"}},{"Gene":"CSNK1E","Gene synonym":["CKIE","CKIepsilon","HCKIE"],"Ensembl":"ENSG00000213923","Gene description":"Casein kinase 1 epsilon","Uniprot":["P49674"],"Chromosome":"22","Position":"38290691-38318084","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"15.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009626","HPA026288"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009626":"AB_2084517","HPA026288":"AB_1847276"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.20e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.67e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"}},{"Gene":"CSNK1G1","Gene synonym":["CK1gamma1"],"Ensembl":"ENSG00000169118","Gene description":"Casein kinase 1 gamma 1","Uniprot":["Q9HCP0"],"Chromosome":"15","Position":"64165525-64356173","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"35.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"87.2","Late spermatids":"250.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018209"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA018209":"AB_1847278"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"}},{"Gene":"CSNK1G2","Gene synonym":["CK1g2"],"Ensembl":"ENSG00000133275","Gene description":"Casein kinase 1 gamma 2","Uniprot":["P78368"],"Chromosome":"19","Position":"1941172-1981338","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"169.5","Late spermatids":"652.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034868","HPA056572"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA034868":"AB_10671235","HPA056572":"AB_2683178"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"}},{"Gene":"CSPG4","Gene synonym":["CSPG4A","HMW-MAA","MCSP","MCSPG","MEL-CSPG","MSK16","NG2"],"Ensembl":"ENSG00000173546","Gene description":"Chondroitin sulfate proteoglycan 4","Uniprot":["Q6UVK1"],"Chromosome":"15","Position":"75674322-75712848","Protein class":["Predicted membrane proteins"],"Biological process":["Angiogenesis","Differentiation","Tissue remodeling"],"Molecular function":["Developmental protein","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"55.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Melanocytes":"17.4","Oligodendrocyte precursor cells":"54.9","Schwann cells":"16.3","Sertoli cells":"55.3","Skeletal myocytes":"14.8","Smooth muscle cells":"49.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"74.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"73.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Colon - Smooth muscle cells","Lung - Smooth muscle cells","Prostate - Smooth muscle cells","Testis - Endothelial cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001933","HPA002951","CAB016189","HPA042785","HPA050008"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"48000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB016189":"AB_784821","HPA001933":null,"HPA002951":"AB_1854449","HPA042785":"AB_10964270","HPA050008":"AB_2680991"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.60e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.93e-5"}},{"Gene":"CSPG5","Gene synonym":["NGC"],"Ensembl":"ENSG00000114646","Gene description":"Chondroitin sulfate proteoglycan 5","Uniprot":["O95196"],"Chromosome":"3","Position":"47562238-47580792","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Growth regulation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"brain":"83.2","choroid plexus":"65.2","retina":"28.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"42.0","Astrocytes":"65.5","Muller glia cells":"83.2","Oligodendrocyte precursor cells":"223.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"19","RNA cancer specific FPKM":{"glioma":"48.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"16.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Skin - Keratinocyte (other)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049529","HPA067818","HPA071779"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA049529":"AB_2680805","HPA067818":"AB_2685905","HPA071779":"AB_2686446"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.14e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"}},{"Gene":"CTAGE1","Gene synonym":["CT21.1","CT21.2","CTAGE","cTAGE-1","cTAGE-2"],"Ensembl":"ENSG00000212710","Gene description":"Cutaneous T cell lymphoma-associated antigen 1","Uniprot":["Q96RT6","Q9HC47"],"Chromosome":"18","Position":"22413599-22417915","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"103","RNA tissue specific nTPM":{"testis":"10.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"147.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000387","HPA000922","CAB016204"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016204":"AB_673617","HPA000387":"AB_1078582","HPA000922":"AB_1078581"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"CTAGE15","Gene synonym":["CTAGE15P"],"Ensembl":"ENSG00000271079","Gene description":"CTAGE family member 15","Uniprot":["A4D2H0"],"Chromosome":"7","Position":"143571801-143574387","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"8.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000387","HPA000922"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000387":"AB_1078582","HPA000922":"AB_1078581"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"}},{"Gene":"CTAGE4","Gene synonym":["cTAGE-4","FLJ43692"],"Ensembl":"ENSG00000225932","Gene description":"CTAGE family member 4","Uniprot":["Q8IX94"],"Chromosome":"7","Position":"144183466-144186053","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"14.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000387","HPA000922"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000387":"AB_1078582","HPA000922":"AB_1078581"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"}},{"Gene":"CTAGE6","Gene synonym":["CTAGE6P","MGC41943"],"Ensembl":"ENSG00000271321","Gene description":"CTAGE family member 6","Uniprot":["Q86UF2"],"Chromosome":"7","Position":"143755089-143757696","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"43","RNA tissue specific nTPM":{"testis":"14.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"5.3","Spermatocytes":"1.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000387","HPA000922"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000387":"AB_1078582","HPA000922":"AB_1078581"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"}},{"Gene":"CTAGE8","Gene synonym":[],"Ensembl":"ENSG00000244693","Gene description":"CTAGE family member 8","Uniprot":["P0CG41"],"Chromosome":"7","Position":"144266701-144269288","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"10.8"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000387","HPA000922"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000387":"AB_1078582","HPA000922":"AB_1078581"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"}},{"Gene":"CTAGE9","Gene synonym":[],"Ensembl":"ENSG00000236761","Gene description":"CTAGE family member 9","Uniprot":["A4FU28"],"Chromosome":"6","Position":"131708441-131711017","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"30","RNA tissue specific nTPM":{"testis":"8.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"5.8","Early spermatids":"19.1","Intestinal goblet cells":"3.4","Paneth cells":"4.7","Spermatocytes":"8.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000387","HPA000922"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000387":"AB_1078582","HPA000922":"AB_1078581"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"}},{"Gene":"CTC1","Gene synonym":["AAF132","C17orf68","FLJ22170"],"Ensembl":"ENSG00000178971","Gene description":"CST telomere replication complex component 1","Uniprot":["Q2NKJ3"],"Chromosome":"17","Position":"8224815-8248056","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052436"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA052436":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.49e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"}},{"Gene":"CTCFL","Gene synonym":["BORIS","CT27","dJ579F20.2"],"Ensembl":"ENSG00000124092","Gene description":"CCCTC-binding factor like","Uniprot":["Q8NI51"],"Chromosome":"20","Position":"57495966-57525652","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Cell cycle","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","DNA-binding","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"11.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"31","RNA single cell type specific nTPM":{"Spermatocytes":"74.3","Spermatogonia":"127.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"4.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"18.1"},"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001472"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA001472":"AB_1078583"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"CTDNEP1","Gene synonym":["DULLARD","HSA011916","NET56"],"Ensembl":"ENSG00000175826","Gene description":"CTD nuclear envelope phosphatase 1","Uniprot":["O95476"],"Chromosome":"17","Position":"7243591-7252491","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"410.0"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037439","HPA066466"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"HPA037439":"AB_10601264","HPA066466":"AB_2732745"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.45e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.81e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"}},{"Gene":"CTLA4","Gene synonym":["CD","CD152","CELIAC3","CTLA-4","GSE","IDDM12"],"Ensembl":"ENSG00000163599","Gene description":"Cytotoxic T-lymphocyte associated protein 4","Uniprot":["P16410"],"Chromosome":"2","Position":"203867771-203873965","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["Diabetes mellitus","Disease variant","FDA approved drug targets","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"37.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Schwann cells":"28.4","T-cells":"54.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"T-reg":"44.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"445","RNA blood lineage specific nTPM":{"T-cells":"44.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"2.9","skin cancer":"5.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Kidney - T-cells","Prostate - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.48e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"}},{"Gene":"CTNNA2","Gene synonym":["CAP-R","CT114"],"Ensembl":"ENSG00000066032","Gene description":"Catenin alpha 2","Uniprot":["P26232"],"Chromosome":"2","Position":"79185231-80648861","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion","Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"99.0","epididymis":"67.0","retina":"80.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"3559.5","Early spermatids":"581.5","Excitatory neurons":"1339.4","Inhibitory neurons":"1031.1","Oligodendrocyte precursor cells":"1249.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"endometrial cancer":"3.9","glioma":"11.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"96","RNA blood cell specific nTPM":{"basophil":"55.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"553","RNA blood lineage specific nTPM":{"granulocytes":"55.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Myeloma":"6.2","Neuroblastoma":"22.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037175"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037175":"AB_476883"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"}},{"Gene":"CTNNAL1","Gene synonym":["alpha-CATU","CLLP"],"Ensembl":"ENSG00000119326","Gene description":"Catenin alpha like 1","Uniprot":["Q9UBT7"],"Chromosome":"9","Position":"108942569-109013522","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"273.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Schwann cells":"293.1","Theca cells":"450.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"6.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.77e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"}},{"Gene":"CTNNB1","Gene synonym":["armadillo","beta-catenin","CTNNB"],"Ensembl":"ENSG00000168036","Gene description":"Catenin beta 1","Uniprot":["P35222"],"Chromosome":"3","Position":"41194741-41260096","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion","Host-virus interaction","Neurogenesis","Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"469.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000108","CAB001950","HPA029159","HPA029160"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB000108":null,"CAB001950":null,"HPA029159":"AB_10599619","HPA029160":"AB_10600996"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.54e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"}},{"Gene":"CTNS","Gene synonym":["CTNS-LSB","PQLC4","SLC66A4"],"Ensembl":"ENSG00000040531","Gene description":"Cystinosin, lysosomal cystine transporter","Uniprot":["O60931"],"Chromosome":"17","Position":"3636459-3663103","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Melanin biosynthesis","Protein transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"36.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"34.3","granulocytes":"27.9","monocytes":"10.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046947"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Vesicles","Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA046947":"AB_2679872"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.33e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.39e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"}},{"Gene":"CTSA","Gene synonym":["GSL","PPGB"],"Ensembl":"ENSG00000064601","Gene description":"Cathepsin A","Uniprot":["P10619"],"Chromosome":"20","Position":"45890144-45898824","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"368.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"310.9","Hofbauer cells":"299.4","Proximal enterocytes":"289.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Kidney - Proximal tubular cells","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB024930","HPA031068","HPA072487"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB024930":null,"HPA031068":"AB_10601205","HPA072487":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.95e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"}},{"Gene":"CTSB","Gene synonym":[],"Ensembl":"ENSG00000164733","Gene description":"Cathepsin B","Uniprot":["P07858"],"Chromosome":"8","Position":"11842524-11869533","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"2520.2","Kupffer cells":"1044.3","Macrophages":"1561.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"1446.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"390.6","classical monocyte":"610.1","intermediate monocyte":"467.3","myeloid DC":"287.4","non-classical monocyte":"307.6","plasmacytoid DC":"410.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"410.1","granulocytes":"390.6","monocytes":"610.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Proximal tubular cells","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000457","HPA018156","HPA048998"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB000457":null,"HPA018156":"AB_1846069","HPA048998":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.76e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.02e-4"}},{"Gene":"CTSC","Gene synonym":["DPP1","PALS","PLS"],"Ensembl":"ENSG00000109861","Gene description":"Cathepsin C","Uniprot":["P53634"],"Chromosome":"11","Position":"88265069-88359684","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"892.7","Club cells":"514.8","Hofbauer cells":"1018.9","Ionocytes":"528.7","Macrophages":"491.4","monocytes":"521.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025364","HPA066610","HPA068434"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB025364":null,"HPA066610":"AB_2685694","HPA068434":"AB_2685989"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.30e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.80e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"}},{"Gene":"CTSH","Gene synonym":["ACC-4","ACC-5","ACC4","ACC5","CPSB"],"Ensembl":"ENSG00000103811","Gene description":"Cathepsin H","Uniprot":["P09668"],"Chromosome":"15","Position":"78921058-78949574","Protein class":["Cancer-related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"349.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 2":"1718.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"208.5","intermediate monocyte":"137.7","memory B-cell":"83.3","myeloid DC":"183.6","naive B-cell":"56.0","non-classical monocyte":"94.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"83.3","dendritic cells":"183.6","monocytes":"208.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Kidney - Proximal tubular cells","Liver - Hepatocytes","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000458","HPA003524"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol","Cytoplasmic bodies"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8700000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Vesicles","Cytosol","Cytoplasmic bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB000458":null,"HPA003524":"AB_1846075"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.90e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"}},{"Gene":"CTSK","Gene synonym":["CTSO","CTSO2","PKND","PYCD"],"Ensembl":"ENSG00000143387","Gene description":"Cathepsin K","Uniprot":["P43235"],"Chromosome":"1","Position":"150794880-150809577","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"420.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"313.6","Langerhans cells":"85.7","Leydig cells":"123.5","Peritubular cells":"151.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"18.1"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"monocytes":"1.8"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"skin cancer":"71.7"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Heart muscle - Fibroblasts","Liver - Hepatic stellate cells","Lung - Fibroblast_2","Prostate - Fibroblasts","Skin - Fibroblast_2","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050346"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA050346":"AB_2681101"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"}},{"Gene":"CTSW","Gene synonym":[],"Ensembl":"ENSG00000172543","Gene description":"Cathepsin W","Uniprot":["P56202"],"Chromosome":"11","Position":"65879809-65883741","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"116.3","lymphoid tissue":"42.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"NK-cells":"922.6","T-cells":"340.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"gdT-cell":"1376.3","MAIT T-cell":"869.4","memory CD8 T-cell":"892.8","naive CD8 T-cell":"636.3","NK-cell":"2276.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"39","RNA blood lineage specific nTPM":{"NK-cells":"2276.1","T-cells":"1376.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"Leukemia":"42.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016345","HPA066903"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016345":"AB_626813","HPA066903":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.06e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.36e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.89e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.84e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"}},{"Gene":"CTU2","Gene synonym":["C16orf84","NCS2"],"Ensembl":"ENSG00000174177","Gene description":"Cytosolic thiouridylase subunit 2","Uniprot":["Q2VPK5"],"Chromosome":"16","Position":"88706483-88715396","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":null,"Disease involvement":["Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041135","HPA041894"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA041135":"AB_10794543","HPA041894":"AB_10796463"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.68e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"}},{"Gene":"CTXN1","Gene synonym":["FLJ25968"],"Ensembl":"ENSG00000178531","Gene description":"Cortexin 1","Uniprot":["P60606"],"Chromosome":"19","Position":"7924491-7926135","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"275.1","endometrium 1":"85.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"131.4","Respiratory ciliated cells":"91.7","Sertoli cells":"30.4","Thymic epithelial cells":"41.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"endometrial cancer":"69.5","glioma":"56.3","ovarian cancer":"138.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Respiratory ciliated cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016669"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane","Cell Junctions"],"Antibody RRID":{"HPA016669":"AB_1847330"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"}},{"Gene":"CTXN2","Gene synonym":[],"Ensembl":"ENSG00000233932","Gene description":"Cortexin 2","Uniprot":["P0C2S0"],"Chromosome":"15","Position":"48178122-48203758","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.9","choroid plexus":"1.6","pituitary gland":"1.1","retina":"1.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"46.1","Late spermatids":"34.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053168"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053168":"AB_2682066"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CTXN3","Gene synonym":[],"Ensembl":"ENSG00000205279","Gene description":"Cortexin 3","Uniprot":["Q4LDR2"],"Chromosome":"5","Position":"127649044-127658630","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"kidney":"79.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Proximal tubular cells":"129.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"renal cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CTXND1","Gene synonym":["LINC01314"],"Ensembl":"ENSG00000259417","Gene description":"Cortexin domain containing 1","Uniprot":["A0A1B0GTU2"],"Chromosome":"15","Position":"80195481-80252213","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"30.9","liver":"9.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"36.1","Cholangiocytes":"19.2","Hepatocytes":"17.2","Inhibitory neurons":"47.2","Melanocytes":"24.4","Oligodendrocyte precursor cells":"58.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"3.4","liver cancer":"2.7","melanoma":"9.1","thyroid cancer":"5.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Rhabdoid":"5.9","skin cancer":"3.7"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hippocampal formation":"35.0"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"CTXND2","Gene synonym":[],"Ensembl":"ENSG00000283324","Gene description":"Cortexin domain containing 2","Uniprot":["A0A1B0GV90"],"Chromosome":"1","Position":"150887136-150913292","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"6.3"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CUL4B","Gene synonym":[],"Ensembl":"ENSG00000158290","Gene description":"Cullin 4B","Uniprot":["Q13620"],"Chromosome":"X","Position":"120505920-120604074","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"101.1","Late spermatids":"174.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003046","HPA011880","CAB017786","HPA058979"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB017786":null,"HPA003046":null,"HPA011880":"AB_1847340","HPA058979":"AB_2683868"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"}},{"Gene":"CUTA","Gene synonym":["ACHAP","C6orf82"],"Ensembl":"ENSG00000112514","Gene description":"CutA divalent cation tolerance homolog","Uniprot":["O60888"],"Chromosome":"6","Position":"33416442-33418317","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016787","HPA064369","HPA070199"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Focal adhesion sites"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"26000000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Plasma membrane","Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"CAB016787":null,"HPA064369":"AB_2685248","HPA070199":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.50e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"}},{"Gene":"CUX1","Gene synonym":["CASP","CDP","CDP\/Cut","CDP\/Cux","CDP1","Clox","CUT","CUTL1","CUX","Cux\/CDP","GOLIM6"],"Ensembl":"ENSG00000257923","Gene description":"Cut like homeobox 1","Uniprot":["P39880","Q13948"],"Chromosome":"7","Position":"101815904-102283958","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation","Transport"],"Molecular function":["Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"35.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003277","HPA003317"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA003277":"AB_10601804","HPA003317":"AB_2666891"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.51e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.72e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"}},{"Gene":"CUX2","Gene synonym":["CDP2","CUTL2","KIAA0293"],"Ensembl":"ENSG00000111249","Gene description":"Cut like homeobox 2","Uniprot":["O14529"],"Chromosome":"12","Position":"111034165-111350554","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"20.6","choroid plexus":"25.7","liver":"20.4","prostate":"11.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"54.8","Excitatory neurons":"173.5","Hepatocytes":"48.9","Inhibitory neurons":"71.0","Prostatic glandular cells":"28.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"5.2","prostate cancer":"11.2"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"20.6"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"70","RNA blood cell specific nTPM":{"plasmacytoid DC":"6.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"70","RNA blood lineage specific nTPM":{"dendritic cells":"6.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"8.9","lymphoma":"7.7","Neuroblastoma":"12.7"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"}},{"Gene":"CUZD1","Gene synonym":["ERG-1","UO-44"],"Ensembl":"ENSG00000138161","Gene description":"CUB and zona pellucida like domains 1","Uniprot":["Q86UP6"],"Chromosome":"10","Position":"122832158-122846175","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion","Cell cycle","Cell division"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"1631","RNA tissue specific nTPM":{"pancreas":"2414.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Exocrine glandular cells":"40.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"54","RNA cancer specific FPKM":{"pancreatic cancer":"32.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068479","HPA068660","HPA074117"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA068479":"AB_2685995","HPA068660":"AB_2686015","HPA074117":"AB_2686663"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-4"}},{"Gene":"CWH43","Gene synonym":["CWH43-C","FLJ21511","PGAP2IP"],"Ensembl":"ENSG00000109182","Gene description":"Cell wall biogenesis 43 C-terminal homolog","Uniprot":["Q9H720"],"Chromosome":"4","Position":"48986275-49062081","Protein class":["Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"21.0","prostate":"42.8","skin 1":"25.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"20.7","Distal enterocytes":"26.6","Endometrial ciliated cells":"40.2","Glandular and luminal cells":"20.8","Prostatic glandular cells":"81.9","Respiratory ciliated cells":"27.3","Suprabasal keratinocytes":"66.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"prostate cancer":"20.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"36","RNA cell line specific nTPM":{"prostate cancer":"18.6"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Intercalated cells","Liver - Hepatocytes","Lung - Respiratory ciliated cells","Prostate - Prostate glandular cells","Stomach - Gastric mucous cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042814","HPA048140"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA042814":"AB_2678182","HPA048140":"AB_2680280"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.29e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"}},{"Gene":"CX3CL1","Gene synonym":["ABCD-3","C3Xkine","CXC3","CXC3C","NTN","SCYD1"],"Ensembl":"ENSG00000006210","Gene description":"C-X3-C motif chemokine ligand 1","Uniprot":["P78423"],"Chromosome":"16","Position":"57372477-57385044","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Chemotaxis","Host-virus interaction","Inflammatory response"],"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"104.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"114.1","Basal respiratory cells":"55.8","Breast glandular cells":"63.7","Club cells":"54.1","Endothelial cells":"51.3","Ionocytes":"114.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026192","HPA040361"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1870000,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB026192":null,"HPA040361":"AB_10796453"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.46e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.52e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"}},{"Gene":"CX3CR1","Gene synonym":["CCRL1","CMKBRL1","CMKDR1","GPR13","V28"],"Ensembl":"ENSG00000168329","Gene description":"C-X3-C motif chemokine receptor 1","Uniprot":["P49238"],"Chromosome":"3","Position":"39263495-39281735","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Inflammatory response","Innate immunity"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Age-related macular degeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"26.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"38.2","Macrophages":"45.8","Microglial cells":"172.4","monocytes":"76.5","NK-cells":"188.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"21.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"449.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Myeloma":"16.6"},"RNA tissue cell type enrichment":["Heart muscle - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032478","HPA046587"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB032478":"AB_638830","HPA046587":"AB_2679708"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"}},{"Gene":"CXADR","Gene synonym":["CAR"],"Ensembl":"ENSG00000154639","Gene description":"CXADR Ig-like cell adhesion molecule","Uniprot":["P78310"],"Chromosome":"21","Position":"17513043-17593579","Protein class":["Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"238.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Skin - Keratinocyte (other)","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003342","CAB005103","HPA030411","HPA030412"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB005103":"AB_2087557","HPA003342":"AB_1078588","HPA030411":"AB_10599620","HPA030412":"AB_10601992"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-3"}},{"Gene":"CXCL16","Gene synonym":["CXCLG16","SR-PSOX","SRPSOX"],"Ensembl":"ENSG00000161921","Gene description":"C-X-C motif chemokine ligand 16","Uniprot":["Q9H2A7"],"Chromosome":"17","Position":"4733533-4739928","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Chemotaxis"],"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Late spermatids":"4113.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"63.3","intermediate monocyte":"107.5","myeloid DC":"38.2","neutrophil":"103.2","non-classical monocyte":"141.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"38.2","granulocytes":"103.2","monocytes":"141.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Ductal cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053253","HPA066315"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1100000,"Blood concentration - Conc. blood MS [pg\/L]":"6800000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA053253":"AB_2682091","HPA066315":"AB_2685657"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"}},{"Gene":"CXCR1","Gene synonym":["CD181","CDw128a","CKR-1","CMKAR1","IL8RA"],"Ensembl":"ENSG00000163464","Gene description":"C-X-C motif chemokine receptor 1","Uniprot":["P25024"],"Chromosome":"2","Position":"218162841-218166962","Protein class":["Cancer-related genes","CD markers","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Chemotaxis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"40.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"NK-cells":"10.0","Serous glandular cells":"4.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"neutrophil":"1472.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"62","RNA blood lineage specific nTPM":{"granulocytes":"1472.7"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Colon - Neutrophils","Heart muscle - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2","Skeletal muscle - Neutrophils","Stomach - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031991"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031991":"AB_2674103"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"}},{"Gene":"CXCR2","Gene synonym":["CD182","CMKAR2","IL8RB"],"Ensembl":"ENSG00000180871","Gene description":"C-X-C motif chemokine receptor 2","Uniprot":["P25025"],"Chromosome":"2","Position":"218125289-218137251","Protein class":["Cancer-related genes","CD markers","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Chemotaxis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"27.2","lymphoid tissue":"40.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"31.3","Serous glandular cells":"15.1","Squamous epithelial cells":"13.8","Suprabasal keratinocytes":"16.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"52","RNA blood cell specific nTPM":{"neutrophil":"3273.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"111","RNA blood lineage specific nTPM":{"granulocytes":"3273.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"5.6"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Colon - Neutrophils","Heart muscle - Neutrophils","Lung - Neutrophil_2","Prostate - Urothelial cells","Skeletal muscle - Neutrophils","Stomach - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016268","HPA031999","HPA032017"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Microtubules","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Microtubules","Mitotic spindle"],"Antibody RRID":{"CAB016268":"AB_626893","HPA031999":"AB_2674105","HPA032017":"AB_2674112"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"}},{"Gene":"CXCR3","Gene synonym":["CD183","CKR-L2","CMKAR3","GPR9","IP10-R","MigR"],"Ensembl":"ENSG00000186810","Gene description":"C-X-C motif chemokine receptor 3","Uniprot":["P49682"],"Chromosome":"X","Position":"71615916-71618511","Protein class":["CD markers","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Angiogenesis","Apoptosis","Chemotaxis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"7.2","intestine":"6.4","lymphoid tissue":"16.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"dendritic cells":"385.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"306.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"306.7","NK-cells":"198.9","T-cells":"124.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"colorectal cancer":"1.6","Leukemia":"1.5","lymphoma":"5.9","Myeloma":"4.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Colon - T-cells","Liver - T-cells","Lung - T-cells","Pancreas - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045942"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045942":"AB_2679507"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.44e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.35e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.67e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"}},{"Gene":"CXCR4","Gene synonym":["CD184","D2S201E","fusin","HM89","HSY3RR","LESTR","NPY3R","NPYR","NPYY3R"],"Ensembl":"ENSG00000121966","Gene description":"C-X-C motif chemokine receptor 4","Uniprot":["P61073"],"Chromosome":"2","Position":"136114349-136118149","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["G-protein coupled receptor","Host cell receptor for virus entry","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1175.1","lymphoid tissue":"549.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1675.4","dendritic cells":"2180.0","monocytes":"1143.3","NK-cells":"1206.4","Schwann cells":"1000.5","T-cells":"1642.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"184.9","lymphoma":"220.2","Myeloma":"144.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Kidney - T-cells","Skin - T-cells","Testis - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.05e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.41e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.67e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"}},{"Gene":"CXCR5","Gene synonym":["BLR1","CD185","MDR15"],"Ensembl":"ENSG00000160683","Gene description":"C-X-C motif chemokine receptor 5","Uniprot":["P32302"],"Chromosome":"11","Position":"118883892-118897787","Protein class":["CD markers","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["B-cell activation"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"10.6","intestine":"10.2","lymphoid tissue":"28.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"B-cells":"84.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"memory B-cell":"67.7","naive B-cell":"92.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"B-cells":"92.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"19.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026149","HPA042432"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026149":null,"HPA042432":"AB_2677995"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-5"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"}},{"Gene":"CXCR6","Gene synonym":["BONZO","CD186","STRL33","TYMSTR"],"Ensembl":"ENSG00000172215","Gene description":"C-X-C motif chemokine receptor 6","Uniprot":["O00574"],"Chromosome":"3","Position":"45940933-45948351","Protein class":["CD markers","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"17.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"88.1","T-cells":"57.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"445.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"445.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"2.0"},"RNA tissue cell type enrichment":["Kidney - T-cells","Lung - T-cells","Pancreas - T-cells","Prostate - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.92e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.74e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.16e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.42e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"}},{"Gene":"CXorf58","Gene synonym":["FLJ25444"],"Ensembl":"ENSG00000165182","Gene description":"Chromosome X open reading frame 58","Uniprot":["Q96LI9"],"Chromosome":"X","Position":"23908006-23939509","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"testis":"3.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"41.7","Spermatocytes":"19.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031542","HPA031543","HPA031544"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA031542":"AB_2673927","HPA031543":"AB_10603789","HPA031544":"AB_2673929"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"}},{"Gene":"CXorf66","Gene synonym":["RP11-35F15.2","SGPX"],"Ensembl":"ENSG00000203933","Gene description":"Chromosome X open reading frame 66","Uniprot":["Q5JRM2"],"Chromosome":"X","Position":"139955728-139965521","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"testis":"13.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"166.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CYB561","Gene synonym":["CYB561A1","FRRS2"],"Ensembl":"ENSG00000008283","Gene description":"Cytochrome b561","Uniprot":["P49447"],"Chromosome":"17","Position":"63432304-63446354","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Prostatic glandular cells":"95.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"pons":"124.7"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Prostate - Prostate glandular cells","Skeletal muscle - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014753"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014753":"AB_1847364"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.89e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.95e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"}},{"Gene":"CYB561A3","Gene synonym":["CYBASC3"],"Ensembl":"ENSG00000162144","Gene description":"Cytochrome b561 family member A3","Uniprot":["Q8NBI2"],"Chromosome":"11","Position":"61348754-61362283","Protein class":["Predicted membrane proteins"],"Biological process":["Electron transport","Transport"],"Molecular function":["Oxidoreductase","Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"251.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"dendritic cells":"289.0","Melanocytes":"543.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"memory B-cell":"314.5","naive B-cell":"386.6","plasmacytoid DC":"841.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"386.6","dendritic cells":"841.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045674","HPA052548"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA045674":null,"HPA052548":"AB_2681866"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"}},{"Gene":"CYB561D1","Gene synonym":["FLJ39035","FLJ44753"],"Ensembl":"ENSG00000174151","Gene description":"Cytochrome b561 family member D1","Uniprot":["Q8N8Q1"],"Chromosome":"1","Position":"109494052-109502932","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"16.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027028"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027028":"AB_1847365"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.68e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.16e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.22e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"}},{"Gene":"CYB561D2","Gene synonym":["101F6","TSP10"],"Ensembl":"ENSG00000114395","Gene description":"Cytochrome b561 family member D2","Uniprot":["O14569"],"Chromosome":"3","Position":"50350845-50358460","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Electron transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071862"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA071862":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.86e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.16e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"}},{"Gene":"CYB5A","Gene synonym":["CYB5"],"Ensembl":"ENSG00000166347","Gene description":"Cytochrome b5 type A","Uniprot":["P00167"],"Chromosome":"18","Position":"74250846-74291973","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"889.6","liver":"2472.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"2071.3","Distal tubular cells":"1530.0","Hepatocytes":"3995.8","Proximal enterocytes":"1932.9","Proximal tubular cells":"2784.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"43.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Kidney - Proximal tubular cells","Liver - Hepatocytes","Lung - Alveolar cells type 2","Skeletal muscle - Fibroblasts","Skin - Sebaceous gland cells","Testis - Leydig cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006333","HPA047548","HPA058547"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB006333":null,"HPA047548":"AB_2680084","HPA058547":"AB_2683750"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.23e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"}},{"Gene":"CYB5B","Gene synonym":["CYB5-M"],"Ensembl":"ENSG00000103018","Gene description":"Cytochrome b5 type B","Uniprot":["O43169"],"Chromosome":"16","Position":"69424619-69466264","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"318.0"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Mitotic cells (Skin)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007893"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"99000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Centriolar satellite","Cytosol"],"Antibody RRID":{"HPA007893":"AB_1847369"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.51e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.38e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"}},{"Gene":"CYB5R2","Gene synonym":[],"Ensembl":"ENSG00000166394","Gene description":"Cytochrome b5 reductase 2","Uniprot":["Q6BCY4"],"Chromosome":"11","Position":"7665100-7677222","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"139.2","testis":"133.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"274.3","Late spermatids":"618.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"eosinophil":"6.1","memory B-cell":"10.6","naive B-cell":"2.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"10.6","granulocytes":"6.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038962","HPA061707"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA038962":"AB_10675954","HPA061707":"AB_2732668"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"}},{"Gene":"CYBA","Gene synonym":["p22-PHOX"],"Ensembl":"ENSG00000051523","Gene description":"Cytochrome b-245 alpha chain","Uniprot":["P13498"],"Chromosome":"16","Position":"88643289-88651054","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Chronic granulomatous disease","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"742.0","lymphoid tissue":"693.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"2027.1","Hofbauer cells":"2756.8","Macrophages":"1698.2","monocytes":"1957.4","Plasma cells":"2225.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"733.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Prostate - T-cells","Skeletal muscle - Fibroblasts","Skin - Fibroblast_2","Testis - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009492","HPA072667"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009492":"AB_2090309","HPA072667":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.19e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.75e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"}},{"Gene":"CYBB","Gene synonym":["CGD","GP91-PHOX","NOX2"],"Ensembl":"ENSG00000165168","Gene description":"Cytochrome b-245 beta chain","Uniprot":["P04839"],"Chromosome":"X","Position":"37780059-37813461","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Ion transport","Transport"],"Molecular function":["Ion channel","Oxidoreductase","Voltage-gated channel"],"Disease involvement":["Chronic granulomatous disease","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"160.9","lymphoid tissue":"158.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"334.1","Hofbauer cells":"226.4","Kupffer cells":"358.4","Macrophages":"451.2","monocytes":"516.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"276.3","intermediate monocyte":"261.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"90.9","granulocytes":"110.5","monocytes":"276.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"17.9","lymphoma":"28.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051227"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051227":"AB_2681395"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"}},{"Gene":"CYBC1","Gene synonym":["C17orf62","Eros","FLJ90469","MGC4368"],"Ensembl":"ENSG00000178927","Gene description":"Cytochrome b-245 chaperone 1","Uniprot":["Q9BQA9"],"Chromosome":"17","Position":"82442586-82450829","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Chaperone"],"Disease involvement":["Chronic granulomatous disease","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045696"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA045696":"AB_2679421"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.83e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-3"}},{"Gene":"CYBRD1","Gene synonym":["CYB561A2","DCYTB","FLJ23462","FRRS3"],"Ensembl":"ENSG00000071967","Gene description":"Cytochrome b reductase 1","Uniprot":["Q53TN4"],"Chromosome":"2","Position":"171522247-171558129","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport"],"Molecular function":["Oxidoreductase","Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"225.6","Leydig cells":"197.5","Peritubular cells":"219.1","Proximal enterocytes":"701.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"17.4","intermediate monocyte":"17.7","myeloid DC":"16.8","neutrophil":"9.8","non-classical monocyte":"13.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"16.8","granulocytes":"9.8","monocytes":"17.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Liver - Hepatic stellate cells","Pancreas - Fibroblasts","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014757"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014757":"AB_1847374"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"}},{"Gene":"CYC1","Gene synonym":["UQCR4"],"Ensembl":"ENSG00000179091","Gene description":"Cytochrome c1","Uniprot":["P08574"],"Chromosome":"8","Position":"144095039-144097525","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"730.0","tongue":"724.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"677.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001247"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"45000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA001247":"AB_1078602"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.89e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"}},{"Gene":"CYFIP2","Gene synonym":["PIR121"],"Ensembl":"ENSG00000055163","Gene description":"Cytoplasmic FMR1 interacting protein 2","Uniprot":["Q96F07"],"Chromosome":"5","Position":"157266079-157395595","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"112.2","kidney":"139.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"129.4","Collecting duct cells":"126.0","Excitatory neurons":"116.1","Inhibitory neurons":"144.0","Oligodendrocyte precursor cells":"115.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"156.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Breast - T-cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB055519","HPA068106","HPA071459"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"CAB055519":null,"HPA068106":"AB_2685955","HPA071459":"AB_2686400"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.42e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.21e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"}},{"Gene":"CYHR1","Gene synonym":["CHRP","KIAA0496","MGC13010"],"Ensembl":"ENSG00000187954","Gene description":"Cysteine and histidine rich 1","Uniprot":["Q6ZMK1"],"Chromosome":"8","Position":"144449582-144465667","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053653","HPA059543"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053653":"AB_2682219","HPA059543":"AB_2684056"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.90e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"CYLD","Gene synonym":["CYLD1","KIAA0849","USPL2"],"Ensembl":"ENSG00000083799","Gene description":"CYLD lysine 63 deubiquitinase","Uniprot":["Q9NQC7"],"Chromosome":"16","Position":"50742050-50801935","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Immunity","Innate immunity","Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Amyotrophic lateral sclerosis","Cancer-related genes","Disease variant","Neurodegeneration","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"94.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011713","HPA050095","HPA077163"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centriolar satellite"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB011713":"AB_731794","HPA050095":"AB_2681013","HPA077163":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"}},{"Gene":"CYP11B1","Gene synonym":["CPN1","CYP11B","FHI","P450C11"],"Ensembl":"ENSG00000160882","Gene description":"Cytochrome P450 family 11 subfamily B member 1","Uniprot":["P15538"],"Chromosome":"8","Position":"142872356-142879846","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroidogenesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Congenital adrenal hyperplasia","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"877","RNA tissue specific nTPM":{"adrenal gland":"3686.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"220","RNA single cell type specific nTPM":{"Early spermatids":"59.7","Late spermatids":"83.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049171","HPA049565","HPA056348","HPA057752"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA049171":"AB_2680661","HPA049565":null,"HPA056348":"AB_2683104","HPA057752":"AB_2683516"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CYP19A1","Gene synonym":["ARO","ARO1","aromatase","CPV1","CYAR","CYP19","P-450AROM"],"Ensembl":"ENSG00000137869","Gene description":"Cytochrome P450 family 19 subfamily A member 1","Uniprot":["P11511"],"Chromosome":"15","Position":"51208057-51338601","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Pseudohermaphroditism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"placenta":"124.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"2701.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.6"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"4.8","hypothalamus":"4.1","medulla oblongata":"1.4","midbrain":"2.0","thalamus":"3.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"6.2","testis cancer":"16.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000355","HPA051194"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB000355":null,"HPA051194":"AB_2681381"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"}},{"Gene":"CYP1A2","Gene synonym":["CP12","P3-450"],"Ensembl":"ENSG00000140505","Gene description":"Cytochrome P450 family 1 subfamily A member 2","Uniprot":["P05177"],"Chromosome":"15","Position":"74748845-74756607","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Lyase","Monooxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"313","RNA tissue specific nTPM":{"liver":"513.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"56","RNA single cell type specific nTPM":{"Hepatocytes":"541.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"22","RNA cancer specific FPKM":{"liver cancer":"25.3","urothelial cancer":"6.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016531"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016531":"AB_629359"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-4"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"}},{"Gene":"CYP1B1","Gene synonym":["CP1B","GLC3A"],"Ensembl":"ENSG00000138061","Gene description":"Cytochrome P450 family 1 subfamily B member 1","Uniprot":["Q16678"],"Chromosome":"2","Position":"38066973-38109902","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Steroid metabolism"],"Molecular function":["Lyase","Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Glaucoma","Peters anomaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"102.3","Fibroblasts":"126.4","Kupffer cells":"118.0","Leydig cells":"158.9","Macrophages":"125.8","Peritubular cells":"171.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"classical monocyte":"156.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"24","RNA blood lineage specific nTPM":{"monocytes":"156.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"34.6"},"Antibody":["CAB011705","HPA026863"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB011705":"AB_731810","HPA026863":"AB_10600900"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.39e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.76e-4"}},{"Gene":"CYP20A1","Gene synonym":["CYP-M"],"Ensembl":"ENSG00000119004","Gene description":"Cytochrome P450 family 20 subfamily A member 1","Uniprot":["Q6UW02"],"Chromosome":"2","Position":"203238977-203306026","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055872","HPA058461"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions","Actin filaments"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Plasma membrane","Cell Junctions","Actin filaments"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA055872":"AB_2682951","HPA058461":"AB_2683725"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"}},{"Gene":"CYP2D6","Gene synonym":["CPD6","CYP2D","CYP2D7AP","CYP2D7BP","CYP2D7P2","CYP2D8P2","CYP2DL1","P450-DB1","P450C2D"],"Ensembl":"ENSG00000100197","Gene description":"Cytochrome P450 family 2 subfamily D member 6","Uniprot":["P10635"],"Chromosome":"22","Position":"42126499-42130865","Protein class":["Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Fatty acid metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"27","RNA tissue specific nTPM":{"liver":"320.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Hepatocytes":"300.8","Proximal enterocytes":"248.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"35","RNA cancer specific FPKM":{"liver cancer":"90.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045223"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA045223":"AB_10962927"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-5"}},{"Gene":"CYP2U1","Gene synonym":["SPG49","SPG56"],"Ensembl":"ENSG00000155016","Gene description":"Cytochrome P450 family 2 subfamily U member 1","Uniprot":["Q7Z449"],"Chromosome":"4","Position":"107931549-107953461","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"lymphoid tissue":"84.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"29.7","Inhibitory neurons":"33.6","Melanocytes":"27.9","Schwann cells":"30.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"2.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041622","HPA046754","HPA064827"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA041622":"AB_2677583","HPA046754":"AB_2679787","HPA064827":"AB_2685362"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.97e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"}},{"Gene":"CYP3A4","Gene synonym":["CYP3A3"],"Ensembl":"ENSG00000160868","Gene description":"Cytochrome P450 family 3 subfamily A member 4","Uniprot":["P08684"],"Chromosome":"7","Position":"99756960-99784248","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"liver":"3796.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"59","RNA single cell type specific nTPM":{"Hepatocytes":"2605.9","Proximal enterocytes":"1368.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"240","RNA cancer specific FPKM":{"liver cancer":"351.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033671","HPA072245","HPA075539"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB033671":"AB_782375","HPA072245":null,"HPA075539":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"}},{"Gene":"CYP3A43","Gene synonym":[],"Ensembl":"ENSG00000021461","Gene description":"Cytochrome P450 family 3 subfamily A member 43","Uniprot":["Q9HB55"],"Chromosome":"7","Position":"99828013-99866102","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"liver":"44.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"4.4","Early spermatids":"5.7","Excitatory neurons":"3.9","Hepatocytes":"3.8","Inhibitory neurons":"1.9","Late spermatids":"4.7","Spermatocytes":"2.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"liver cancer":"1.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Prostate - Prostate glandular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066463","HPA072245","HPA075539"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA066463":"AB_2685670","HPA072245":null,"HPA075539":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.41e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-4"}},{"Gene":"CYP3A5","Gene synonym":["CP35","P450PCN3","PCN3"],"Ensembl":"ENSG00000106258","Gene description":"Cytochrome P450 family 3 subfamily A member 5","Uniprot":["P20815"],"Chromosome":"7","Position":"99648194-99679998","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Steroid metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"177.7","liver":"276.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"400.3","Distal enterocytes":"216.9","Gastric mucus-secreting cells":"531.2","Hepatocytes":"415.6","Proximal enterocytes":"1080.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"38.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Colon - Colon enterocytes","Liver - Hepatocytes","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072245","HPA075539"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA072245":null,"HPA075539":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.72e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-3"}},{"Gene":"CYP3A7","Gene synonym":["CP37","P450-HFLA"],"Ensembl":"ENSG00000160870","Gene description":"Cytochrome P450 family 3 subfamily A member 7","Uniprot":["P24462"],"Chromosome":"7","Position":"99705036-99735196","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"36","RNA tissue specific nTPM":{"liver":"304.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Cholangiocytes":"88.5","Hepatocytes":"33.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"43","RNA cancer specific FPKM":{"liver cancer":"38.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072245","HPA075539"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA072245":null,"HPA075539":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"}},{"Gene":"CYP3A7-CYP3A51P","Gene synonym":[],"Ensembl":"ENSG00000282301","Gene description":"CYP3A7-CYP3A51P readthrough","Uniprot":[],"Chromosome":"7","Position":"99684957-99735102","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"liver":"12.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cholangiocytes":"3.8","Hepatocytes":"1.1"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072245","HPA075539"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA072245":null,"HPA075539":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"CYP4A11","Gene synonym":["CYP4A2","CYP4AII"],"Ensembl":"ENSG00000187048","Gene description":"Cytochrome P450 family 4 subfamily A member 11","Uniprot":["Q02928"],"Chromosome":"1","Position":"46929177-46941484","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"333","RNA tissue specific nTPM":{"kidney":"218.8","liver":"857.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatocytes":"454.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"73.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"}},{"Gene":"CYP4A22","Gene synonym":[],"Ensembl":"ENSG00000162365","Gene description":"Cytochrome P450 family 4 subfamily A member 22","Uniprot":["Q5TCH4"],"Chromosome":"1","Position":"47137435-47149735","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"liver":"214.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Hepatocytes":"98.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"liver cancer":"20.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-4"}},{"Gene":"CYP4B1","Gene synonym":[],"Ensembl":"ENSG00000142973","Gene description":"Cytochrome P450 family 4 subfamily B member 1","Uniprot":["P13584"],"Chromosome":"1","Position":"46757838-46819413","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"242.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"150.2","Basal prostatic cells":"122.6","Club cells":"373.4","Ionocytes":"264.4","Respiratory ciliated cells":"653.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"56.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"11.1","breast cancer":"16.7"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Lung - Alveolar cells type 1","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004331"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA004331":"AB_1078616"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.99e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-3"}},{"Gene":"CYP4F2","Gene synonym":[],"Ensembl":"ENSG00000186115","Gene description":"Cytochrome P450 family 4 subfamily F member 2","Uniprot":["P78329"],"Chromosome":"19","Position":"15878023-15898077","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"80.2","kidney":"40.9","liver":"166.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Hepatocytes":"114.8","Proximal enterocytes":"205.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"29.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"basophil":"8.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"82","RNA blood lineage specific nTPM":{"granulocytes":"8.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.7","Gastric cancer":"1.1"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Prostate - Prostate glandular cells","Skin - Sebaceous gland cells","Stomach - Gastric enteroendocrine cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014048","HPA017265","HPA058960"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014048":"AB_1847452","HPA017265":"AB_1847451","HPA058960":"AB_2683862"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-3"}},{"Gene":"CYP4F22","Gene synonym":["FLJ39501"],"Ensembl":"ENSG00000171954","Gene description":"Cytochrome P450 family 4 subfamily F member 22","Uniprot":["Q6NT55"],"Chromosome":"19","Position":"15508525-15552317","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"18.8","skin 1":"58.6","vagina":"22.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"54.4","Breast glandular cells":"8.6","Prostatic glandular cells":"11.2","Suprabasal keratinocytes":"31.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"breast cancer":"4.5","head and neck cancer":"5.7","liver cancer":"8.5","melanoma":"4.5","urothelial cancer":"13.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"intermediate monocyte":"6.1","MAIT T-cell":"4.3","non-classical monocyte":"14.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"monocytes":"14.1","T-cells":"4.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"40","RNA cell line specific nTPM":{"Bone cancer":"47.2"},"RNA tissue cell type enrichment":["Lung - T-cells","Skin - Keratinocyte (granular)","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058960"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058960":"AB_2683862"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"}},{"Gene":"CYP4F8","Gene synonym":[],"Ensembl":"ENSG00000186526","Gene description":"Cytochrome P450 family 4 subfamily F member 8","Uniprot":["P98187"],"Chromosome":"19","Position":"15615218-15630639","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"seminal vesicle":"215.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"42","RNA single cell type specific nTPM":{"Basal prostatic cells":"1221.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"10.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"18","RNA cell line specific nTPM":{"prostate cancer":"15.2"},"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058960"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058960":"AB_2683862"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-6"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"}},{"Gene":"CYP4V2","Gene synonym":["CYP4AH1"],"Ensembl":"ENSG00000145476","Gene description":"Cytochrome P450 family 4 subfamily V member 2","Uniprot":["Q6ZWL3"],"Chromosome":"4","Position":"186191567-186213463","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sensory transduction","Vision"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"113.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"90.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029122"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029122":"AB_10601806"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.86e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.49e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"}},{"Gene":"CYP4X1","Gene synonym":["MGC40051"],"Ensembl":"ENSG00000186377","Gene description":"Cytochrome P450 family 4 subfamily X member 1","Uniprot":["Q8N118"],"Chromosome":"1","Position":"47023669-47050751","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"37.1","salivary gland":"31.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"37.0","Club cells":"56.2","Excitatory neurons":"36.9","Inhibitory neurons":"28.6","Ionocytes":"40.4","Respiratory ciliated cells":"38.4","Salivary duct cells":"43.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"24.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"7.9","prostate cancer":"12.9"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Stomach - Chief cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017661"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017661":"AB_2669633"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"}},{"Gene":"CYP4Z1","Gene synonym":["CYP4A20"],"Ensembl":"ENSG00000186160","Gene description":"Cytochrome P450 family 4 subfamily Z member 1","Uniprot":["Q86W10"],"Chromosome":"1","Position":"47067231-47118318","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"6.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"6.0","Early spermatids":"1.9","Excitatory neurons":"8.1","Inhibitory neurons":"5.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"50","RNA cancer specific FPKM":{"breast cancer":"42.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"breast cancer":"1.6","lymphoma":"4.8"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"}},{"Gene":"CYP51A1","Gene synonym":["CP51","CYP51","CYPL1","LDM","P450-14DM","P450L1"],"Ensembl":"ENSG00000001630","Gene description":"Cytochrome P450 family 51 subfamily A member 1","Uniprot":["Q16850"],"Chromosome":"7","Position":"92112153-92134803","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"204.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"49.0","Kupffer cells":"82.7","Oligodendrocytes":"50.1","Squamous epithelial cells":"50.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Macrophages","Liver - Hepatocytes","Lung - Alveolar cells type 2","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041325","HPA043508"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA041325":"AB_2677411","HPA043508":"AB_2678520"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.12e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"}},{"Gene":"CYP7A1","Gene synonym":["CYP7"],"Ensembl":"ENSG00000167910","Gene description":"Cytochrome P450 family 7 subfamily A member 1","Uniprot":["P22680"],"Chromosome":"8","Position":"58490178-58500163","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"80","RNA tissue specific nTPM":{"liver":"49.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Hepatocytes":"6.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"96","RNA cancer specific FPKM":{"liver cancer":"28.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"CYP7B1","Gene synonym":["SPG5A"],"Ensembl":"ENSG00000172817","Gene description":"Cytochrome P450 family 7 subfamily B member 1","Uniprot":["O75881"],"Chromosome":"8","Position":"64587763-64798737","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Intrahepatic cholestasis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"27.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"90.8","Oligodendrocyte precursor cells":"90.5","Oligodendrocytes":"112.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"basophil":"2.5","eosinophil":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"25","RNA blood lineage specific nTPM":{"granulocytes":"2.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"2.8"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017761"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017761":"AB_1847455"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-3"}},{"Gene":"CYP8B1","Gene synonym":["CYP12"],"Ensembl":"ENSG00000180432","Gene description":"Cytochrome P450 family 8 subfamily B member 1","Uniprot":["Q9UNU6"],"Chromosome":"3","Position":"42856005-42875898","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"liver":"404.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"61","RNA single cell type specific nTPM":{"Hepatocytes":"791.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"46","RNA cancer specific FPKM":{"liver cancer":"69.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"}},{"Gene":"CYSLTR1","Gene synonym":["CysLT(1)","CysLT1","CYSLT1R"],"Ensembl":"ENSG00000173198","Gene description":"Cysteinyl leukotriene receptor 1","Uniprot":["Q9Y271"],"Chromosome":"X","Position":"78271468-78327691","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"11.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"27.6","B-cells":"62.5","dendritic cells":"69.2","granulocytes":"37.0","Hofbauer cells":"36.4","Macrophages":"32.7","monocytes":"43.3","Plasma cells":"41.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"85.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Leukemia":"7.3","lymphoma":"2.7","Myeloma":"6.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010546"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010546":"AB_1078268"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"}},{"Gene":"CYSLTR2","Gene synonym":["CysLT(2)","CYSLT2R"],"Ensembl":"ENSG00000152207","Gene description":"Cysteinyl leukotriene receptor 2","Uniprot":["Q9NS75"],"Chromosome":"13","Position":"48653711-48711226","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"25.8","seminal vesicle":"17.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"19.3","Macrophages":"10.1","Melanocytes":"22.6","monocytes":"56.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"6.6","thyroid cancer":"7.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"eosinophil":"100.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"100.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"4.5","lymphoma":"5.0","Neuroblastoma":"4.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046528"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046528":"AB_2679687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"}},{"Gene":"CYSTM1","Gene synonym":["C5orf32","ORF1-FL49"],"Ensembl":"ENSG00000120306","Gene description":"Cysteine rich transmembrane module containing 1","Uniprot":["Q9H1C7"],"Chromosome":"5","Position":"140175156-140282052","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"stomach 1":"1317.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"1126.1","Distal tubular cells":"2285.6","Gastric mucus-secreting cells":"2172.6","Late spermatids":"1697.7","Proximal tubular cells":"1241.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"425.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"425.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050930"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050930":"AB_2681278"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.31e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.71e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.69e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"}},{"Gene":"CYTH2","Gene synonym":["ARNO","CTS18.1","cytohesin-2","PSCD2","PSCD2L","Sec7p-L","Sec7p-like"],"Ensembl":"ENSG00000105443","Gene description":"Cytohesin 2","Uniprot":["Q99418"],"Chromosome":"19","Position":"48469208-48482314","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"290.7","Late spermatids":"188.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB014872","HPA060662"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Golgi apparatus","Plasma membrane"],"Antibody RRID":{"CAB014872":null,"HPA060662":"AB_2732652"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.21e-4"}},{"Gene":"CYYR1","Gene synonym":["C21orf95"],"Ensembl":"ENSG00000166265","Gene description":"Cysteine and tyrosine rich 1","Uniprot":["Q96J86"],"Chromosome":"21","Position":"26466209-26573286","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Adipocytes":"190.8","Endothelial cells":"162.0","Microglial cells":"56.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"38","RNA blood cell specific nTPM":{"plasmacytoid DC":"31.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"82","RNA blood lineage specific nTPM":{"dendritic cells":"31.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"14.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034921","HPA067685"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB034921":"AB_2089315","HPA067685":"AB_2685887"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"}},{"Gene":"DAAM2","Gene synonym":["KIAA0381"],"Ensembl":"ENSG00000146122","Gene description":"Dishevelled associated activator of morphogenesis 2","Uniprot":["Q86T65"],"Chromosome":"6","Position":"39792298-39904877","Protein class":["Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"245.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"267.0","Oligodendrocytes":"424.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"15.0","melanoma":"21.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"skin cancer":"57.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051300","HPA054630"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA051300":"AB_2681430","HPA054630":"AB_2682549"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.79e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-4"}},{"Gene":"DAD1","Gene synonym":["OST2"],"Ensembl":"ENSG00000129562","Gene description":"Defender against cell death 1","Uniprot":["P61803"],"Chromosome":"14","Position":"22564907-22589224","Protein class":["Cancer-related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028882"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA028882":"AB_10602214"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.73e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"}},{"Gene":"DAG1","Gene synonym":["156DAG","A3a","AGRNR","DAG"],"Ensembl":"ENSG00000173402","Gene description":"Dystroglycan 1","Uniprot":["Q14118"],"Chromosome":"3","Position":"49468703-49535618","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Limb-girdle muscular dystrophy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"210.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001960","CAB016353","HPA070563"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"84000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB001960":null,"CAB016353":"AB_627292","HPA070563":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.59e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"}},{"Gene":"DAGLA","Gene synonym":["C11orf11","DAGLALPHA","KIAA0659","NSDDR"],"Ensembl":"ENSG00000134780","Gene description":"Diacylglycerol lipase alpha","Uniprot":["Q9Y4D2"],"Chromosome":"11","Position":"61680391-61747001","Protein class":["Disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"12.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"12.3","Excitatory neurons":"14.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062497","CAB078793"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB078793":null,"HPA062497":"AB_2684784"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"}},{"Gene":"DAGLB","Gene synonym":["DAGLBETA","KCCR13L"],"Ensembl":"ENSG00000164535","Gene description":"Diacylglycerol lipase beta","Uniprot":["Q8NCG7"],"Chromosome":"7","Position":"6409126-6484190","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069377"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA069377":"AB_2686132"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.18e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.54e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"}},{"Gene":"DAP3","Gene synonym":["bMRP-10","DAP-3","DKFZp686G12159","MGC126058","MGC126059","MRP-S29","MRPS29"],"Ensembl":"ENSG00000132676","Gene description":"Death associated protein 3","Uniprot":["P51398"],"Chromosome":"1","Position":"155687960-155739010","Protein class":["Plasma proteins","Predicted intracellular proteins","Ribosomal proteins"],"Biological process":["Apoptosis"],"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023687"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA023687":"AB_1847472"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"}},{"Gene":"DAPK1","Gene synonym":["DAPK","ROCO3"],"Ensembl":"ENSG00000196730","Gene description":"Death associated protein kinase 1","Uniprot":["P53355"],"Chromosome":"9","Position":"87497228-87708634","Protein class":["Cancer-related genes","Enzymes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Apoptosis","Translation regulation"],"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"134.7","Excitatory neurons":"118.5","Inhibitory neurons":"152.0","Thymic epithelial cells":"122.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"6.7","eosinophil":"8.7","intermediate monocyte":"14.0","myeloid DC":"4.8","non-classical monocyte":"15.2","plasmacytoid DC":"6.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"56","RNA blood lineage specific nTPM":{"dendritic cells":"6.2","granulocytes":"8.7","monocytes":"15.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003516","CAB037302","HPA040472","HPA048436"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"CAB037302":"AB_1078622","HPA003516":null,"HPA040472":"AB_2677001","HPA048436":"AB_2680390"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"}},{"Gene":"DAPK2","Gene synonym":["DRP-1","MGC119312"],"Ensembl":"ENSG00000035664","Gene description":"Death associated protein kinase 2","Uniprot":["Q9UIK4"],"Chromosome":"15","Position":"63907036-64072033","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"50.2","thyroid gland":"41.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"92.3","Late spermatids":"112.9","Oligodendrocytes":"94.3","Proximal enterocytes":"54.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"thyroid cancer":"30.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"basophil":"94.3","eosinophil":"213.0","neutrophil":"65.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"25","RNA blood lineage specific nTPM":{"granulocytes":"213.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071581"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA071581":"AB_2686421"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.63e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"}},{"Gene":"DAPK3","Gene synonym":["ZIP","ZIPK"],"Ensembl":"ENSG00000167657","Gene description":"Death associated protein kinase 3","Uniprot":["O43293"],"Chromosome":"19","Position":"3958453-3971123","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Transcription","Transcription regulation","Translation regulation"],"Molecular function":["Activator","Chromatin regulator","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028569"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA028569":"AB_10794319"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.01e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"}},{"Gene":"DAPL1","Gene synonym":[],"Ensembl":"ENSG00000163331","Gene description":"Death associated protein like 1","Uniprot":["A0PJW8"],"Chromosome":"2","Position":"158795317-158862781","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"196.9","esophagus":"242.0","skin 1":"301.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"236.9","Basal squamous epithelial cells":"310.7","Muller glia cells":"870.4","Squamous epithelial cells":"810.7","Suprabasal keratinocytes":"331.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"62.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"prostate cancer":"304.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046937","HPA058635"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm","Nuclear bodies","Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA046937":"AB_2679870","HPA058635":"AB_2732625"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.43e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"}},{"Gene":"DBF4B","Gene synonym":["ASKL1","chifb","DRF1","FLJ13087","ZDBF1B"],"Ensembl":"ENSG00000161692","Gene description":"DBF4 zinc finger B","Uniprot":["Q8NFT6"],"Chromosome":"17","Position":"44708608-44752264","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"22.9","Horizontal cells":"25.6","Oligodendrocytes":"29.1","Spermatocytes":"36.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048465","HPA077959"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA048465":"AB_2680405","HPA077959":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"}},{"Gene":"DBH","Gene synonym":["DBM"],"Ensembl":"ENSG00000123454","Gene description":"Dopamine beta-hydroxylase","Uniprot":["P09172"],"Chromosome":"9","Position":"133636363-133659329","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Catecholamine biosynthesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"adrenal gland":"272.7","brain":"236.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Theca cells":"2.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"1.7"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"pons":"236.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"21","RNA cell line specific nTPM":{"Neuroblastoma":"192.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"pons and medulla":"22.1"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"26","RNA pig brain regional specific nTPM":{"pons":"18.5"},"Antibody":["HPA002130","HPA005960","HPA070789"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA002130":"AB_2666554","HPA005960":"AB_1078628","HPA070789":"AB_2686312"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"}},{"Gene":"DBNDD2","Gene synonym":["C20orf35","HSMNP1"],"Ensembl":"ENSG00000244274","Gene description":"Dysbindin domain containing 2","Uniprot":["Q9BQY9"],"Chromosome":"20","Position":"45406057-45410610","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1300.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"25.1","Gastric mucus-secreting cells":"21.5","Macrophages":"8.4","Smooth muscle cells":"19.8","Squamous epithelial cells":"32.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"dendritic cells":"18.7","monocytes":"12.5","T-cells":"9.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Breast - Smooth muscle cells","Colon - Smooth muscle cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043991"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043991":"AB_10966212"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"}},{"Gene":"DBT","Gene synonym":["BCKAD-E2","BCKDH-E2","BCOADC-E2"],"Ensembl":"ENSG00000137992","Gene description":"Dihydrolipoamide branched chain transacylase E2","Uniprot":["P11182"],"Chromosome":"1","Position":"100186919-100249834","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Maple syrup urine disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"92.5","Prostatic glandular cells":"68.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"64.7"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026481","HPA026485","HPA026533"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA026481":"AB_1847504","HPA026485":"AB_1847505","HPA026533":"AB_1847506"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.79e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"}},{"Gene":"DCAF15","Gene synonym":["C19orf72","MGC99481"],"Ensembl":"ENSG00000132017","Gene description":"DDB1 and CUL4 associated factor 15","Uniprot":["Q66K64"],"Chromosome":"19","Position":"13952492-13961449","Protein class":["Predicted intracellular proteins"],"Biological process":["Immunity","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Skin - Keratinocyte (other)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068351"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA068351":"AB_2685977"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.97e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"}},{"Gene":"DCAF17","Gene synonym":["C2orf37","FLJ13096"],"Ensembl":"ENSG00000115827","Gene description":"DDB1 and CUL4 associated factor 17","Uniprot":["Q5H9S7"],"Chromosome":"2","Position":"171434217-171485052","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Deafness","Diabetes mellitus","Hypotrichosis","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"53.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053339","HPA055040"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053339":"AB_2682119","HPA055040":"AB_2682680"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.10e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"}},{"Gene":"DCAKD","Gene synonym":["FLJ22955"],"Ensembl":"ENSG00000172992","Gene description":"Dephospho-CoA kinase domain containing","Uniprot":["Q8WVC6"],"Chromosome":"17","Position":"45023340-45061109","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060997"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA060997":"AB_2797262"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.16e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"}},{"Gene":"DCBLD1","Gene synonym":["dJ94G16.1","MGC46341"],"Ensembl":"ENSG00000164465","Gene description":"Discoidin, CUB and LCCL domain containing 1","Uniprot":["Q8N8Z6"],"Chromosome":"6","Position":"117453817-117569858","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"34.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059667"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"22000000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA059667":"AB_2684099"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.44e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.57e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"DCBLD2","Gene synonym":["CLCP1","ESDN"],"Ensembl":"ENSG00000057019","Gene description":"Discoidin, CUB and LCCL domain containing 2","Uniprot":["Q96PD2"],"Chromosome":"3","Position":"98795941-98901695","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"110.9","Sertoli cells":"105.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016909"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2200000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA016909":"AB_1847510"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.32e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.87e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"}},{"Gene":"DCC","Gene synonym":["IGDCC1","NTN1R1"],"Ensembl":"ENSG00000187323","Gene description":"DCC netrin 1 receptor","Uniprot":["P43146"],"Chromosome":"18","Position":"52340197-53535903","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"6.9","testis":"7.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"165.1","Excitatory neurons":"432.1","Inhibitory neurons":"444.1","Late spermatids":"190.5","Oligodendrocyte precursor cells":"1250.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"7.4","Myeloma":"19.9"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Plasma cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055376","HPA069552"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"64000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA055376":"AB_2682798","HPA069552":"AB_2686151"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"}},{"Gene":"DCHS1","Gene synonym":["CDH25","CDHR6","FIB1","FLJ11790","KIAA1773","PCDH16"],"Ensembl":"ENSG00000166341","Gene description":"Dachsous cadherin-related 1","Uniprot":["Q96JQ0"],"Chromosome":"11","Position":"6621330-6655809","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"33.5","Endometrial stromal cells":"15.5","Endothelial cells":"29.3","Fibroblasts":"18.8","Granulosa cells":"18.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"12.9","Neuroblastoma":"25.8","Sarcoma":"6.5"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Kidney - Endothelial cells","Lung - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017970","HPA050246"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA017970":"AB_2669718","HPA050246":"AB_2681062"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"}},{"Gene":"DCHS2","Gene synonym":["CDH27","CDHJ","CDHR7","FLJ20047","PCDH23","PCDHJ"],"Ensembl":"ENSG00000197410","Gene description":"Dachsous cadherin-related 2","Uniprot":["Q6V1P9"],"Chromosome":"4","Position":"154231742-154491799","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"1.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"61.0","Early spermatids":"15.9","Excitatory neurons":"29.7","Inhibitory neurons":"12.9","Late spermatids":"22.3","Microglial cells":"12.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064159"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA064159":"AB_2685201"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"}},{"Gene":"DCLK1","Gene synonym":["DCAMKL1","DCDC3A","DCLK","KIAA0369"],"Ensembl":"ENSG00000133083","Gene description":"Doublecortin like kinase 1","Uniprot":["O15075"],"Chromosome":"13","Position":"35768652-36131382","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"53.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"955.7","Inhibitory neurons":"649.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"12.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"46.5"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Heart muscle - Fibroblasts","Lung - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012405","HPA015040","HPA015655"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB012405":null,"HPA015040":"AB_2669141","HPA015655":"AB_2669265"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-4"}},{"Gene":"DCLK2","Gene synonym":["DCAMKL2","DCDC3","DCDC3B","DCK2","MGC45428"],"Ensembl":"ENSG00000170390","Gene description":"Doublecortin like kinase 2","Uniprot":["Q8N568"],"Chromosome":"4","Position":"150078445-150257438","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"59.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"485.5","Excitatory neurons":"187.0","Inhibitory neurons":"169.3","Oligodendrocyte precursor cells":"165.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"glioma":"53.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"10.3"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015770"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015770":"AB_1847509"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.25e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.48e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"}},{"Gene":"DCLK3","Gene synonym":["DCAMKL3","DCDC3C","KIAA1765"],"Ensembl":"ENSG00000163673","Gene description":"Doublecortin like kinase 3","Uniprot":["Q9C098"],"Chromosome":"3","Position":"36712422-36764349","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.9","testis":"2.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Early spermatids":"67.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"testis cancer":"1.2"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"3.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"1.2"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040685","HPA053234"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA040685":"AB_2732487","HPA053234":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"}},{"Gene":"DCST1","Gene synonym":["FLJ32785"],"Ensembl":"ENSG00000163357","Gene description":"DC-STAMP domain containing 1","Uniprot":["Q5T197"],"Chromosome":"1","Position":"155033824-155050930","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"2.6","skin 1":"3.1","testis":"6.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"8.6","Early spermatids":"35.9","Late spermatids":"17.9","Rod photoreceptor cells":"6.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060314"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060314":"AB_2684250"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"DCST2","Gene synonym":["FLJ32934"],"Ensembl":"ENSG00000163354","Gene description":"DC-STAMP domain containing 2","Uniprot":["Q5T1A1"],"Chromosome":"1","Position":"155018520-155033781","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"8.5","skin 1":"4.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"15.5","Early spermatids":"61.7","Extravillous trophoblasts":"16.0","Late spermatids":"30.9","Rod photoreceptor cells":"14.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-3"}},{"Gene":"DCSTAMP","Gene synonym":["DC-STAMP","FIND","TM7SF4"],"Ensembl":"ENSG00000164935","Gene description":"Dendrocyte expressed seven transmembrane protein","Uniprot":["Q9H295"],"Chromosome":"8","Position":"104339087-104356689","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"4.5","epididymis":"2.0","lung":"3.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hofbauer cells":"6.5","Macrophages":"8.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"46","RNA cancer specific FPKM":{"thyroid cancer":"45.3"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"4.5","basal ganglia":"2.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"2.0","thyroid cancer":"3.0"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-3"}},{"Gene":"DCT","Gene synonym":["TYRP2"],"Ensembl":"ENSG00000080166","Gene description":"Dopachrome tautomerase","Uniprot":["P40126"],"Chromosome":"13","Position":"94436811-94479682","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Melanin biosynthesis"],"Molecular function":["Isomerase"],"Disease involvement":["Albinism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"35","RNA tissue specific nTPM":{"skin 1":"107.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"56","RNA single cell type specific nTPM":{"Melanocytes":"9253.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"215","RNA cancer specific FPKM":{"melanoma":"155.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"21","RNA cell line specific nTPM":{"skin cancer":"355.5"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skin - Melanocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010742","HPA010743","HPA010800","CAB017634"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB017634":"AB_1130818","HPA010742":null,"HPA010743":"AB_1847519","HPA010800":"AB_1847520"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"}},{"Gene":"DDAH2","Gene synonym":["G6A"],"Ensembl":"ENSG00000213722","Gene description":"Dimethylarginine dimethylaminohydrolase 2","Uniprot":["O95865"],"Chromosome":"6","Position":"31727038-31730617","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"341.3","Langerhans cells":"321.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012389","HPA012509"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA012389":null,"HPA012509":"AB_1847533"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"}},{"Gene":"DDOST","Gene synonym":["GATD6","KIAA0115","OST","OST48","WBP1"],"Ensembl":"ENSG00000244038","Gene description":"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit","Uniprot":["P39656"],"Chromosome":"1","Position":"20651767-20661544","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"352.6","Plasma cells":"369.2","Syncytiotrophoblasts":"349.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Macrophages","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009746","HPA046841","HPA052867"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB009746":"AB_2092075","HPA046841":"AB_2679834","HPA052867":"AB_2681977"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.99e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.88e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.64e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.05e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"DDR1","Gene synonym":["CAK","CD167","EDDR1","NEP","NTRK4","PTK3A","RTK6"],"Ensembl":"ENSG00000204580","Gene description":"Discoidin domain receptor tyrosine kinase 1","Uniprot":["Q08345"],"Chromosome":"6","Position":"30876421-30900156","Protein class":["CD markers","Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lactation","Pregnancy"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Stomach - Gastric mucous cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010162","CAB025656","HPA057194"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4400000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB010162":"AB_2092090","CAB025656":null,"HPA057194":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.31e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"}},{"Gene":"DDR2","Gene synonym":["NTRKR3","TKT","TYRO10"],"Ensembl":"ENSG00000162733","Gene description":"Discoidin domain receptor tyrosine kinase 2","Uniprot":["Q16832"],"Chromosome":"1","Position":"162631373-162787405","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Osteogenesis"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"86.1","Fibroblasts":"127.3","Leydig cells":"64.0","Peritubular cells":"87.2","Smooth muscle cells":"77.2","Thymic epithelial cells":"70.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"43.6"},"RNA tissue cell type enrichment":["Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070112"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"770000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Plasma membrane","Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA070112":"AB_2686229"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"}},{"Gene":"DDX23","Gene synonym":["prp28","PRPF28","SNRNP100","U5-100K"],"Ensembl":"ENSG00000174243","Gene description":"DEAD-box helicase 23","Uniprot":["Q9BUQ8"],"Chromosome":"12","Position":"48829756-48852842","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Helicase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038680","HPA039037"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA038680":"AB_10795401","HPA039037":"AB_2676317"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"DDX27","Gene synonym":["dJ686N3.1","DRS1"],"Ensembl":"ENSG00000124228","Gene description":"DEAD-box helicase 27","Uniprot":[],"Chromosome":"20","Position":"49219347-49244077","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047087","HPA053455"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA047087":"AB_10964059","HPA053455":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.44e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.70e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"}},{"Gene":"DDX39B","Gene synonym":["BAT1","D6S81E","UAP56"],"Ensembl":"ENSG00000198563","Gene description":"DExD-box helicase 39B","Uniprot":["Q13838"],"Chromosome":"6","Position":"31530219-31542448","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA processing","mRNA splicing","mRNA transport","Transport"],"Molecular function":["Helicase","Hydrolase","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034012","HPA055334","HPA058450"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"CAB034012":"AB_2243237","HPA055334":"AB_2682787","HPA058450":"AB_2683721"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.43e-5"}},{"Gene":"DDX3X","Gene synonym":["DBX","DDX14","DDX3","HLP2"],"Ensembl":"ENSG00000215301","Gene description":"DEAD-box helicase 3 X-linked","Uniprot":["O00571"],"Chromosome":"X","Position":"41333348-41364472","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Chromosome partition","Host-virus interaction","Immunity","Innate immunity","Ribosome biogenesis","Transcription","Transcription regulation","Translation regulation"],"Molecular function":["DNA-binding","Helicase","Hydrolase","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"906.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001648","HPA005631","HPA059585"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA001648":"AB_1078635","HPA005631":"AB_1078633","HPA059585":"AB_2684073"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"}},{"Gene":"DEDD","Gene synonym":["CASP8IP1","DEDD1","DEFT","FLDED1","KE05"],"Ensembl":"ENSG00000158796","Gene description":"Death effector domain containing","Uniprot":["O75618"],"Chromosome":"1","Position":"161120974-161132688","Protein class":["Predicted intracellular proteins"],"Biological process":["Apoptosis","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064486","HPA065101","HPA073628"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA064486":null,"HPA065101":null,"HPA073628":"AB_2732230"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.98e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"}},{"Gene":"DEGS1","Gene synonym":["DEGS-1","Des-1","DES1","FADS7","MLD"],"Ensembl":"ENSG00000143753","Gene description":"Delta 4-desaturase, sphingolipid 1","Uniprot":["O15121"],"Chromosome":"1","Position":"224175756-224193441","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Isomerase","Oxidoreductase"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"skin 1":"535.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"275.5","Suprabasal keratinocytes":"212.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076422"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA076422":"AB_2686799"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.74e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.29e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.83e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-4"}},{"Gene":"DEGS2","Gene synonym":["C14orf66","DES2","FADS8"],"Ensembl":"ENSG00000168350","Gene description":"Delta 4-desaturase, sphingolipid 2","Uniprot":["Q6QHC5"],"Chromosome":"14","Position":"100143957-100159645","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"37.0","intestine":"34.8","skin 1":"54.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"320.4","Respiratory ciliated cells":"135.7","Squamous epithelial cells":"105.6","Suprabasal keratinocytes":"138.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"3.5","eosinophil":"6.6","memory B-cell":"10.9","naive B-cell":"6.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"10.9","granulocytes":"6.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"18.1","Gastric cancer":"11.6"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Lung - Respiratory ciliated cells","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046644"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA046644":"AB_2797231"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.94e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.66e-4"}},{"Gene":"DELE1","Gene synonym":["DELE","KIAA0141"],"Ensembl":"ENSG00000081791","Gene description":"DAP3 binding cell death enhancer 1","Uniprot":["Q14154"],"Chromosome":"5","Position":"141923855-141942047","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036548","HPA061490"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA036548":"AB_10673356","HPA061490":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.89e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-3"}},{"Gene":"DENND4B","Gene synonym":["KIAA0476"],"Ensembl":"ENSG00000198837","Gene description":"DENN domain containing 4B","Uniprot":["O75064"],"Chromosome":"1","Position":"153929501-153946718","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"43.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040188","HPA071133"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA040188":"AB_10671168","HPA071133":"AB_2732173"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.14e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.18e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.27e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"}},{"Gene":"DENND5A","Gene synonym":["FLJ22354","FLJ33829","FLJ43455","KIAA1091","RAB6IP1"],"Ensembl":"ENSG00000184014","Gene description":"DENN domain containing 5A","Uniprot":["Q6IQ26"],"Chromosome":"11","Position":"9138825-9265959","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"145.3","monocytes":"225.5","Oligodendrocyte precursor cells":"130.4","Oligodendrocytes":"271.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052923","HPA055009"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA052923":"AB_2681989","HPA055009":"AB_2682669"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.05e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"}},{"Gene":"DENND5B","Gene synonym":["MGC24039"],"Ensembl":"ENSG00000170456","Gene description":"DENN domain containing 5B","Uniprot":["Q6ZUT9"],"Chromosome":"12","Position":"31382226-31591136","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"148.0","Excitatory neurons":"214.2","Inhibitory neurons":"240.9","Oligodendrocyte precursor cells":"138.1","Oligodendrocytes":"114.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.4","naive B-cell":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"testis cancer":"57.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038865"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA038865":"AB_2676245"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"}},{"Gene":"DENND6B","Gene synonym":["AFI1B","FAM116B","MGC33692"],"Ensembl":"ENSG00000205593","Gene description":"DENN domain containing 6B","Uniprot":["Q8NEG7"],"Chromosome":"22","Position":"50309030-50327012","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"40.3","Late spermatids":"57.9","Respiratory ciliated cells":"83.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018934","HPA021653","HPA029570"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA018934":"AB_1848365","HPA021653":"AB_1848366","HPA029570":"AB_10602131"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.41e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.93e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"}},{"Gene":"DEPDC5","Gene synonym":["DEP.5","KIAA0645"],"Ensembl":"ENSG00000100150","Gene description":"DEP domain containing 5, GATOR1 subcomplex subunit","Uniprot":["O75140"],"Chromosome":"22","Position":"31753867-31908033","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"34.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"34.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054969","HPA055619"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054969":"AB_2682655","HPA055619":"AB_2682864"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.46e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.86e-5"}},{"Gene":"DERA","Gene synonym":["CGI-26","DEOC"],"Ensembl":"ENSG00000023697","Gene description":"Deoxyribose-phosphate aldolase","Uniprot":["Q9Y315"],"Chromosome":"12","Position":"15911302-16037381","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"104.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"144.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055897"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA055897":"AB_2682963"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.64e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"}},{"Gene":"DERL1","Gene synonym":["DER-1","DER1","derlin-1","FLJ13784","MGC3067","PRO2577"],"Ensembl":"ENSG00000136986","Gene description":"Derlin 1","Uniprot":["Q9BUN8"],"Chromosome":"8","Position":"123013170-123042302","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction","Protein transport","Transport","Unfolded protein response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"259.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016562","CAB037269"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB037269":"AB_609868","HPA016562":"AB_1847611"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.43e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.66e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.58e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"}},{"Gene":"DERL2","Gene synonym":["CGI-101","derlin-2","F-LAN-1","F-LANa","FLANa"],"Ensembl":"ENSG00000072849","Gene description":"Derlin 2","Uniprot":["Q9GZP9"],"Chromosome":"17","Position":"5471254-5486811","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction","Unfolded protein response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"264.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037287","HPA048957","HPA056551"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB037287":"AB_1078641","HPA048957":"AB_2680570","HPA056551":"AB_2683171"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.26e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"}},{"Gene":"DERL3","Gene synonym":["C22orf14","derlin-3","FLJ43842","IZP6","MGC71803"],"Ensembl":"ENSG00000099958","Gene description":"Derlin 3","Uniprot":["Q96Q80"],"Chromosome":"22","Position":"23834503-23839128","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"61.6","pancreas":"60.8","salivary gland":"51.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Plasma cells":"1365.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"plasmacytoid DC":"187.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"dendritic cells":"187.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Myeloma":"39.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Plasma cells","Adipose visceral - Plasma cells","Breast - Plasma cells","Lung - Plasma cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037234","HPA049306"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB037234":"AB_1840802","HPA049306":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.70e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.01e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.76e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"}},{"Gene":"DESI2","Gene synonym":["C1orf121","CGI-146","DESI-2","FAM152A","FLJ21998","PNAS-4","PPPDE1"],"Ensembl":"ENSG00000121644","Gene description":"Desumoylating isopeptidase 2","Uniprot":["Q9BSY9"],"Chromosome":"1","Position":"244653103-244709033","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"190.5","Spermatocytes":"180.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049950"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049950":"AB_2680969"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.25e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"}},{"Gene":"DEUP1","Gene synonym":["CCDC67","FLJ25393"],"Ensembl":"ENSG00000165325","Gene description":"Deuterosome assembly protein 1","Uniprot":["Q05D60"],"Chromosome":"11","Position":"93329971-93438487","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"4.8","testis":"16.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"353.2","Late spermatids":"186.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Prostate - Prostate glandular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"}},{"Gene":"DEXI","Gene synonym":["MYLE"],"Ensembl":"ENSG00000182108","Gene description":"Dexi homolog","Uniprot":["O95424"],"Chromosome":"16","Position":"10928891-10942468","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"116.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041511"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA041511":"AB_10796675"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.23e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"}},{"Gene":"DFFB","Gene synonym":["CAD","CPAN","DFF-40","DFF40"],"Ensembl":"ENSG00000169598","Gene description":"DNA fragmentation factor subunit beta","Uniprot":["O76075"],"Chromosome":"1","Position":"3857267-3885429","Protein class":["Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":["Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"4.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"31.0","Extravillous trophoblasts":"34.7","Oligodendrocytes":"21.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004328","HPA052904"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB004328":"AB_626776","HPA052904":"AB_2681985"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.29e-5"}},{"Gene":"DGAT1","Gene synonym":["ARGP1","DGAT"],"Ensembl":"ENSG00000185000","Gene description":"Diacylglycerol O-acyltransferase 1","Uniprot":["O75907"],"Chromosome":"8","Position":"144314584-144326910","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"40.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"657.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032853"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Nucleoli rim","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoli","Nucleoli rim"],"Antibody RRID":{"CAB032853":"AB_2090798"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"}},{"Gene":"DGAT2","Gene synonym":[],"Ensembl":"ENSG00000062282","Gene description":"Diacylglycerol O-acyltransferase 2","Uniprot":["Q96PD7"],"Chromosome":"11","Position":"75759512-75801535","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Glycerol metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"adipose tissue":"476.0","breast":"133.6","liver":"331.8","skin 1":"151.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"254.6","Hepatocytes":"104.3","Late spermatids":"96.6","Spermatocytes":"56.7","Spermatogonia":"47.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"19.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"eosinophil":"137.7","neutrophil":"348.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"granulocytes":"348.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Lung - Neutrophil_2","Skin - Keratinocyte (granular)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"22.0"},"Antibody":["HPA013351"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA013351":"AB_1847630"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.84e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"}},{"Gene":"DGAT2L6","Gene synonym":["DC3","FLJ25989"],"Ensembl":"ENSG00000184210","Gene description":"Diacylglycerol O-acyltransferase 2 like 6","Uniprot":["Q6ZPD8"],"Chromosome":"X","Position":"70177483-70205704","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"40","RNA tissue specific nTPM":{"breast":"2.1","skin 1":"5.8"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"testis cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"DGCR2","Gene synonym":["DGS-C","IDD","KIAA0163","LAN","SEZ-12"],"Ensembl":"ENSG00000070413","Gene description":"DiGeorge syndrome critical region gene 2","Uniprot":["P98153"],"Chromosome":"22","Position":"19036282-19122454","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000873"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"84000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000873":"AB_1847632"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.72e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-3"}},{"Gene":"DGKE","Gene synonym":["DAGK6","DGK"],"Ensembl":"ENSG00000153933","Gene description":"Diacylglycerol kinase epsilon","Uniprot":["P52429"],"Chromosome":"17","Position":"56834107-56869567","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"34.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"170.4","Cone photoreceptor cells":"153.4","Inhibitory neurons":"88.0","Rod photoreceptor cells":"168.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017167"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017167":"AB_1847638"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.92e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"}},{"Gene":"DGKH","Gene synonym":["DGKeta"],"Ensembl":"ENSG00000102780","Gene description":"Diacylglycerol kinase eta","Uniprot":["Q86XP1"],"Chromosome":"13","Position":"42040036-42256578","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"25.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Respiratory ciliated cells":"93.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"25.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039533","HPA040355","HPA061538"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA039533":"AB_10795145","HPA040355":"AB_10796452","HPA061538":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"}},{"Gene":"DGKI","Gene synonym":["DGK-IOTA"],"Ensembl":"ENSG00000157680","Gene description":"Diacylglycerol kinase iota","Uniprot":["O75912"],"Chromosome":"7","Position":"137381037-137847092","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"19.2","choroid plexus":"9.2","retina":"6.5","thyroid gland":"15.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"597.2","Inhibitory neurons":"405.1","Oligodendrocyte precursor cells":"315.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"0.8","melanoma":"0.6","renal cancer":"1.0","thyroid cancer":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"5.5"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"}},{"Gene":"DGKZ","Gene synonym":["DAGK5","DAGK6","DGK-ZETA","hDGKzeta"],"Ensembl":"ENSG00000149091","Gene description":"Diacylglycerol kinase zeta","Uniprot":["Q13574"],"Chromosome":"11","Position":"46332905-46380554","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"146.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"112.4","Extravillous trophoblasts":"119.7","NK-cells":"120.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"27","RNA brain regional specific nTPM":{"amygdala":"46.5","basal ganglia":"75.1","cerebral cortex":"146.2","hippocampal formation":"133.8","white matter":"51.0"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051336"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA051336":"AB_2681448"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.74e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-3"}},{"Gene":"DHCR24","Gene synonym":["DCE","KIAA0018","seladin-1"],"Ensembl":"ENSG00000116133","Gene description":"24-dehydrocholesterol reductase","Uniprot":["Q15392"],"Chromosome":"1","Position":"54849627-54887195","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"1129.5","liver":"623.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"342.3","Alveolar cells type 2":"502.0","Hepatocytes":"834.8","Kupffer cells":"367.5","Suprabasal keratinocytes":"289.8","Theca cells":"296.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Liver - Hepatocytes","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Testis - Leydig cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017981","CAB037247","HPA063005"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037247":"AB_796187","HPA017981":"AB_2732422","HPA063005":"AB_2684919"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"}},{"Gene":"DHCR7","Gene synonym":["SLOS"],"Ensembl":"ENSG00000172893","Gene description":"7-dehydrocholesterol reductase","Uniprot":["Q9UBM7"],"Chromosome":"11","Position":"71428193-71452868","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"161.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"102.9","Basal respiratory cells":"77.6","Granulosa cells":"78.1","Hepatocytes":"130.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Lung - Alveolar cells type 2","Skin - Sebaceous gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044280"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA044280":"AB_10794893"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.93e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.67e-4"}},{"Gene":"DHODH","Gene synonym":[],"Ensembl":"ENSG00000102967","Gene description":"Dihydroorotate dehydrogenase (quinone)","Uniprot":["Q02127"],"Chromosome":"16","Position":"72008588-72027664","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Pyrimidine biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"liver":"105.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"134.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010123","HPA011942"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA010123":"AB_1847648","HPA011942":"AB_1847649"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"}},{"Gene":"DHRS3","Gene synonym":["RDH17","retSDR1","Rsdr1","SDR1","SDR16C1"],"Ensembl":"ENSG00000162496","Gene description":"Dehydrogenase\/reductase 3","Uniprot":["O75911"],"Chromosome":"1","Position":"12567910-12618210","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"323.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"401.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"gdT-cell":"86.8","MAIT T-cell":"63.1","memory CD4 T-cell":"46.9","memory CD8 T-cell":"41.0","myeloid DC":"24.0","naive CD4 T-cell":"79.2","naive CD8 T-cell":"50.1","NK-cell":"41.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"24.0","NK-cells":"41.1","T-cells":"86.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010844"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoli","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA010844":"AB_1847653"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.65e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"}},{"Gene":"DHRS7B","Gene synonym":["CGI-93","DKFZp566O084","MGC8916","SDR32C1"],"Ensembl":"ENSG00000109016","Gene description":"Dehydrogenase\/reductase 7B","Uniprot":["Q6IAN0"],"Chromosome":"17","Position":"21123364-21193265","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"56.8"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012132","HPA016873"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Plasma membrane","Cell Junctions","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA012132":"AB_1847658","HPA016873":"AB_1847657"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.98e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.95e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"}},{"Gene":"DHRS9","Gene synonym":["3alpha-HSD","RDH15","RDHL","RETSDR8","SDR9C4"],"Ensembl":"ENSG00000073737","Gene description":"Dehydrogenase\/reductase 9","Uniprot":["Q9BPW9"],"Chromosome":"2","Position":"169064789-169096167","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Steroid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"53.9","intestine":"70.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"155.1","Distal enterocytes":"149.2","Early spermatids":"168.8","Ionocytes":"257.3","Respiratory ciliated cells":"132.6","Syncytiotrophoblasts":"449.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"16.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"258.3","eosinophil":"99.2","neutrophil":"77.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"258.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"140.7","pancreatic cancer":"92.5"},"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036491","HPA036667"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036491":"AB_10673498","HPA036667":"AB_10670237"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"}},{"Gene":"DIO1","Gene synonym":["TXDI1"],"Ensembl":"ENSG00000211452","Gene description":"Iodothyronine deiodinase 1","Uniprot":["P49895"],"Chromosome":"1","Position":"53891239-53911086","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Thyroid hormones biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"42","RNA tissue specific nTPM":{"kidney":"144.9","liver":"185.3","thyroid gland":"260.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hepatocytes":"59.5","Proximal tubular cells":"66.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"liver cancer":"44.7","thyroid cancer":"43.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"breast cancer":"3.5","liver cancer":"2.7","prostate cancer":"4.6","thyroid cancer":"8.9"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.44e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"}},{"Gene":"DIO2","Gene synonym":["SelY","TXDI2"],"Ensembl":"ENSG00000211448","Gene description":"Iodothyronine deiodinase 2","Uniprot":["Q92813"],"Chromosome":"14","Position":"80197526-80387757","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Thyroid hormones biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"163.9","thyroid gland":"355.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"96.9","Endometrial stromal cells":"144.1","Extravillous trophoblasts":"590.3","Muller glia cells":"194.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"34.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"77.6","Brain cancer":"83.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Heart muscle - Fibroblasts","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048002"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA048002":"AB_2680230"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.67e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.62e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"}},{"Gene":"DIO3","Gene synonym":["TXDI3"],"Ensembl":"ENSG00000197406","Gene description":"Iodothyronine deiodinase 3","Uniprot":["P55073"],"Chromosome":"14","Position":"101561351-101563452","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Thyroid hormones biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"25.0","placenta":"17.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"71.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"9.5","testis cancer":"5.2"},"RNA tissue cell type enrichment":["Prostate - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"amygdala":"4.4","hippocampal formation":"5.6"},"Antibody":["HPA073684"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA073684":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-3"}},{"Gene":"DIP2C","Gene synonym":["KIAA0934"],"Ensembl":"ENSG00000151240","Gene description":"Disco interacting protein 2 homolog C","Uniprot":["Q9Y2E4"],"Chromosome":"10","Position":"274190-689668","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"121.5","Excitatory neurons":"216.2","Inhibitory neurons":"263.7","Oligodendrocyte precursor cells":"207.0","Oligodendrocytes":"398.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030264","HPA059325"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA030264":"AB_10600903","HPA059325":"AB_2683979"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.92e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.46e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-3"}},{"Gene":"DIPK1A","Gene synonym":["FAM69A","FLJ23493"],"Ensembl":"ENSG00000154511","Gene description":"Divergent protein kinase domain 1A","Uniprot":["Q5T7M9"],"Chromosome":"1","Position":"92832737-92961522","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"80.0","Excitatory neurons":"112.0","Inhibitory neurons":"142.4","Oligodendrocyte precursor cells":"126.1","Oligodendrocytes":"152.4","Plasma cells":"59.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"79.3"},"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015718","HPA017281"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA015718":"AB_1848405","HPA017281":"AB_1848406"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.96e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.45e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"}},{"Gene":"DIPK1B","Gene synonym":["C9orf136","FAM69B","MGC20262"],"Ensembl":"ENSG00000165716","Gene description":"Divergent protein kinase domain 1B","Uniprot":["Q5VUD6"],"Chromosome":"9","Position":"136712572-136724742","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"54.8","Endothelial cells":"41.4","Glandular and luminal cells":"27.0","Horizontal cells":"38.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"2.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"2.8","dendritic cells":"1.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054443"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA054443":"AB_2682489"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.77e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.48e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"}},{"Gene":"DIRAS3","Gene synonym":["ARHI","NOEY2"],"Ensembl":"ENSG00000162595","Gene description":"DIRAS family GTPase 3","Uniprot":["O95661"],"Chromosome":"1","Position":"68045886-68051631","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"143.9","ovary":"60.1","pituitary gland":"52.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"68.4","Enteroendocrine cells":"32.0","Theca cells":"134.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"endometrial cancer":"4.3","glioma":"16.3","pancreatic cancer":"5.6","thyroid cancer":"13.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"22.0","Rhabdoid":"27.0"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028483","HPA028557","HPA029384"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nuclear membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028483":"AB_10599599","HPA028557":"AB_10602091","HPA029384":"AB_10601343"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.21e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-3"}},{"Gene":"DIS3L2","Gene synonym":["FAM6A","FLJ36974","MGC42174"],"Ensembl":"ENSG00000144535","Gene description":"DIS3 like 3'-5' exoribonuclease 2","Uniprot":["Q8IYB7"],"Chromosome":"2","Position":"231961245-232344350","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Exonuclease","Hydrolase","Nuclease","RNA-binding"],"Disease involvement":["Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"81.9","Excitatory neurons":"81.5","Inhibitory neurons":"91.3","Oligodendrocytes":"142.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035796","HPA035797"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035796":"AB_2674786","HPA035797":"AB_10669978"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.41e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"}},{"Gene":"DISP1","Gene synonym":["DISPA","DKFZP434I0428","MGC13130","MGC16796"],"Ensembl":"ENSG00000154309","Gene description":"Dispatched RND transporter family member 1","Uniprot":["Q96F81"],"Chromosome":"1","Position":"222815022-223005995","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"198.8","Oligodendrocyte precursor cells":"191.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Fibroblasts","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051411"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA051411":"AB_2681475"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.00e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.86e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.16e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-3"}},{"Gene":"DISP2","Gene synonym":["C15orf36","DISPB","HsT16908","KIAA1742","LINC00594"],"Ensembl":"ENSG00000140323","Gene description":"Dispatched RND transporter family member 2","Uniprot":["A7MBM2"],"Chromosome":"15","Position":"40358219-40378621","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"17.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"13.9","Distal enterocytes":"18.2","Enteroendocrine cells":"14.8","Horizontal cells":"35.2","Intestinal goblet cells":"16.4","Proximal enterocytes":"12.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059903"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059903":"AB_2684156"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"}},{"Gene":"DISP3","Gene synonym":["KIAA1337","PTCHD2"],"Ensembl":"ENSG00000204624","Gene description":"Dispatched RND transporter family member 3","Uniprot":["Q9P2K9"],"Chromosome":"1","Position":"11479155-11537551","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Differentiation","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"9.8","pituitary gland":"3.5","retina":"4.6","testis":"6.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"29.4","Early spermatids":"19.0","Horizontal cells":"52.6","Late spermatids":"43.0","Rod photoreceptor cells":"15.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"3.4"},"RNA tissue cell type enrichment":["Pancreas - Beta cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054579"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA054579":"AB_2682529"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"DLK1","Gene synonym":["Delta1","FA1","pG2","Pref-1","ZOG"],"Ensembl":"ENSG00000185559","Gene description":"Delta like non-canonical Notch ligand 1","Uniprot":["P80370"],"Chromosome":"14","Position":"100725705-100738224","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adrenal gland":"1330.8","pituitary gland":"772.9","placenta":"1631.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Leydig cells":"1379.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"28.1","testis cancer":"25.4"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hypothalamus":"163.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"Neuroblastoma":"442.9","Rhabdoid":"319.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"111.7"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"hypothalamus":"41.2","midbrain":"156.8"},"Antibody":["CAB005872","HPA062262"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2600000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB005872":"AB_731965","HPA062262":"AB_2684729"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.31e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"DLK2","Gene synonym":["EGFL9","MGC2487"],"Ensembl":"ENSG00000171462","Gene description":"Delta like non-canonical Notch ligand 2","Uniprot":["Q6UY11"],"Chromosome":"6","Position":"43450352-43456632","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"12.3","prostate":"12.9","skin 1":"12.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"20.3","Basal respiratory cells":"51.7","Basal squamous epithelial cells":"44.6","Breast myoepithelial cells":"32.2","Salivary duct cells":"30.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"41.3"},"RNA tissue cell type enrichment":["Prostate - Prostate basal glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061223","HPA068672","HPA070955"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Vesicles"],"Antibody RRID":{"HPA061223":"AB_2684454","HPA068672":"AB_2686017","HPA070955":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"}},{"Gene":"DLL1","Gene synonym":[],"Ensembl":"ENSG00000198719","Gene description":"Delta like canonical Notch ligand 1","Uniprot":["O00548"],"Chromosome":"6","Position":"170282206-170306565","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Notch signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Autism spectrum disorder","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"53.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"87.1","Basal keratinocytes":"54.8","Basal squamous epithelial cells":"88.0","Intestinal goblet cells":"74.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"NK-cell":"3.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"NK-cells":"3.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"11.5"},"RNA tissue cell type enrichment":["Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001255"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"690000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA001255":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"}},{"Gene":"DLL3","Gene synonym":["SCDO1"],"Ensembl":"ENSG00000090932","Gene description":"Delta like canonical Notch ligand 3","Uniprot":["Q9NYJ7"],"Chromosome":"19","Position":"39498895-39508481","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Notch signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"5.7","choroid plexus":"2.3","pituitary gland":"3.4","testis":"1.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"23.6","Spermatogonia":"42.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"29.2","melanoma":"15.5","testis cancer":"8.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"2.6","naive CD8 T-cell":"1.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"B-cells":"2.6","T-cells":"1.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"22.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024559","HPA056533"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 47: Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Plasma membrane"],"Antibody RRID":{"HPA024559":null,"HPA056533":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.94e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"}},{"Gene":"DLL4","Gene synonym":[],"Ensembl":"ENSG00000128917","Gene description":"Delta like canonical Notch ligand 4","Uniprot":["Q9NR61"],"Chromosome":"15","Position":"40929340-40939073","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Angiogenesis","Differentiation","Neurogenesis","Notch signaling pathway","Sensory transduction","Vision"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"64.6","Endothelial cells":"51.4","Intestinal goblet cells":"28.8","Undifferentiated cells":"23.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"4.2","lung cancer":"4.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Colon - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023392"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023392":"AB_1847740"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.97e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-3"}},{"Gene":"DMAC1","Gene synonym":["C9orf123","MGC4730","TMEM261"],"Ensembl":"ENSG00000137038","Gene description":"Distal membrane arm assembly complex 1","Uniprot":["Q96GE9"],"Chromosome":"9","Position":"7796500-7888380","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"457.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014585"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014585":"AB_1845803"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.15e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.96e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"}},{"Gene":"DMD","Gene synonym":["BMD","DXS142","DXS164","DXS206","DXS230","DXS239","DXS268","DXS269","DXS270","DXS272","MRX85"],"Ensembl":"ENSG00000198947","Gene description":"Dystrophin","Uniprot":["P11532"],"Chromosome":"X","Position":"31097677-33339609","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"632.7","Excitatory neurons":"1257.4","Inhibitory neurons":"701.1","Oligodendrocyte precursor cells":"1112.4","Oligodendrocytes":"576.0","Rod photoreceptor cells":"401.8","Skeletal myocytes":"722.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"8.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"4.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"1.1","granulocytes":"4.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Kidney - Fibroblasts","Liver - Hepatocytes","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000119","HPA002725","HPA023885"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000119":null,"HPA002725":"AB_1078714","HPA023885":"AB_1847931"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"}},{"Gene":"DMPK","Gene synonym":["DM","DM1","DM1PK","DMK","MDPK","MT-PK"],"Ensembl":"ENSG00000104936","Gene description":"DM1 protein kinase","Uniprot":["Q09013"],"Chromosome":"19","Position":"45769709-45782552","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cataract"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"42.7","Skeletal myocytes":"67.3","Smooth muscle cells":"40.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Liver - Vascular Endothelial cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"8.7"},"Antibody":["HPA007164","HPA008905"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA007164":"AB_1078687","HPA008905":"AB_1078685"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.39e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"}},{"Gene":"DMRT2","Gene synonym":[],"Ensembl":"ENSG00000173253","Gene description":"Doublesex and mab-3 related transcription factor 2","Uniprot":["Q9Y5R5"],"Chromosome":"9","Position":"1049858-1057552","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"41.2","lymphoid tissue":"20.9","parathyroid gland":"46.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Distal tubular cells":"118.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"lung cancer":"3.0","renal cancer":"9.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Esophageal cancer":"6.4","Sarcoma":"5.8"},"RNA tissue cell type enrichment":["Kidney - Intercalated cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebral cortex":"1.1"},"Antibody":["HPA003498","HPA029297"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Vesicles","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Vesicles","Centriolar satellite"],"Antibody RRID":{"HPA003498":null,"HPA029297":"AB_10600905"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"}},{"Gene":"DMXL1","Gene synonym":[],"Ensembl":"ENSG00000172869","Gene description":"Dmx like 1","Uniprot":["Q9Y485"],"Chromosome":"5","Position":"119037772-119249138","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"143.8","Oligodendrocytes":"211.5","Prostatic glandular cells":"185.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"14.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036431","HPA036432"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":["Nucleoli","Nucleoli fibrillar center"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA036431":"AB_10669791","HPA036432":"AB_2675120"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.16e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"}},{"Gene":"DMXL2","Gene synonym":["DFNA71","KIAA0856","RC3"],"Ensembl":"ENSG00000104093","Gene description":"Dmx like 2","Uniprot":["Q8TDJ6"],"Chromosome":"15","Position":"51447711-51622833","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Diabetes mellitus","Disease variant","Epilepsy","Hypogonadotropic hypogonadism","Neuropathy","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"136.9","Inhibitory neurons":"120.1","Kupffer cells":"84.4","Macrophages":"102.3","monocytes":"120.0","Oligodendrocyte precursor cells":"92.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"2.8","intermediate monocyte":"2.2","neutrophil":"2.2","non-classical monocyte":"2.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2.2","monocytes":"2.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039375"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039375":"AB_10673610"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"}},{"Gene":"DNAAF5","Gene synonym":["CILD18","FLJ20397","FLJ25564","FLJ31671","FLJ39381","HEATR2"],"Ensembl":"ENSG00000164818","Gene description":"Dynein axonemal assembly factor 5","Uniprot":["Q86Y56"],"Chromosome":"7","Position":"726699-786475","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Kartagener syndrome","Primary ciliary dyskinesia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020243"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA020243":"AB_1848750"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.42e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.83e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-3"}},{"Gene":"DNAH10","Gene synonym":["FLJ43808"],"Ensembl":"ENSG00000197653","Gene description":"Dynein axonemal heavy chain 10","Uniprot":["Q8IVF4"],"Chromosome":"12","Position":"123762188-123935720","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.9","choroid plexus":"2.6","fallopian tube":"4.1","testis":"3.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"30.3","Endometrial ciliated cells":"87.1","Late spermatids":"63.4","Respiratory ciliated cells":"86.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039066"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039066":"AB_10673237"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"}},{"Gene":"DNAH14","Gene synonym":["C1orf67","DKFZp781B1548","Dnahc14","HL-18","HL18","MGC27277"],"Ensembl":"ENSG00000185842","Gene description":"Dynein axonemal heavy chain 14","Uniprot":["Q0VDD8"],"Chromosome":"1","Position":"224896262-225399292","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"22.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"143.6","Excitatory neurons":"64.4","Late spermatids":"52.7","Spermatocytes":"69.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027718","HPA028545","HPA031379"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA027718":"AB_10601210","HPA028545":"AB_2672665","HPA031379":"AB_2673851"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"}},{"Gene":"DNAH2","Gene synonym":["DNHD3","FLJ46675","KIAA1503"],"Ensembl":"ENSG00000183914","Gene description":"Dynein axonemal heavy chain 2","Uniprot":["Q9P225"],"Chromosome":"17","Position":"7717354-7833744","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"13.1","parathyroid gland":"10.5","retina":"21.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Respiratory ciliated cells":"47.2","Rod photoreceptor cells":"133.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Lung - Respiratory ciliated cells","Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067103"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA067103":"AB_2685778"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"}},{"Gene":"DNAH3","Gene synonym":["DKFZp434N074","DLP3","Dnahc3b","Hsadhc3"],"Ensembl":"ENSG00000158486","Gene description":"Dynein axonemal heavy chain 3","Uniprot":["Q8TD57"],"Chromosome":"16","Position":"20933111-21159441","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.2","fallopian tube":"5.1","testis":"4.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"42.2","Endometrial ciliated cells":"26.2","Late spermatids":"20.6","Respiratory ciliated cells":"53.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"}},{"Gene":"DNAJB12","Gene synonym":["DJ10","FLJ20027"],"Ensembl":"ENSG00000148719","Gene description":"DnaJ heat shock protein family (Hsp40) member B12","Uniprot":["Q9NXW2"],"Chromosome":"10","Position":"72332830-72355149","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"236.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010642","HPA072702"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nuclear membrane","Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA010642":"AB_1078692","HPA072702":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.79e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.17e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"}},{"Gene":"DNAJB14","Gene synonym":["FLJ14281"],"Ensembl":"ENSG00000164031","Gene description":"DnaJ heat shock protein family (Hsp40) member B14","Uniprot":["Q8TBM8"],"Chromosome":"4","Position":"99896248-99946618","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036016"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036016":"AB_10670594"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.12e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"}},{"Gene":"DNAJC1","Gene synonym":["DNAJL1","ERdj1","MTJ1"],"Ensembl":"ENSG00000136770","Gene description":"DnaJ heat shock protein family (Hsp40) member C1","Uniprot":["Q96KC8"],"Chromosome":"10","Position":"21756548-22003769","Protein class":["Predicted membrane proteins","Transcription factors"],"Biological process":null,"Molecular function":["Chaperone","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"131.8"},"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013432"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA013432":"AB_1847797"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.96e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"}},{"Gene":"DNAJC10","Gene synonym":["ERdj5","PDIA19"],"Ensembl":"ENSG00000077232","Gene description":"DnaJ heat shock protein family (Hsp40) member C10","Uniprot":["Q8IXB1"],"Chromosome":"2","Position":"182716255-182794464","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"113.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"225.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031111"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031111":"AB_10601211"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.42e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.19e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.27e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"}},{"Gene":"DNAJC11","Gene synonym":["FLJ10737"],"Ensembl":"ENSG00000007923","Gene description":"DnaJ heat shock protein family (Hsp40) member C11","Uniprot":["Q9NVH1"],"Chromosome":"1","Position":"6634168-6701924","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023707","HPA028705"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA023707":null,"HPA028705":"AB_10603662"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.63e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"DNAJC12","Gene synonym":["JDP1"],"Ensembl":"ENSG00000108176","Gene description":"DnaJ heat shock protein family (Hsp40) member C12","Uniprot":["Q9UKB3"],"Chromosome":"10","Position":"67796669-67838188","Protein class":["Disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"70.3","liver":"67.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"81.0","Enteroendocrine cells":"137.3","Hepatocytes":"102.7","Pancreatic endocrine cells":"147.7","Proximal tubular cells":"150.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"22.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"plasmacytoid DC":"7.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"24","RNA blood lineage specific nTPM":{"dendritic cells":"7.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036289"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036289":"AB_10670794"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.97e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"}},{"Gene":"DNAJC13","Gene synonym":["KIAA0678","RME8"],"Ensembl":"ENSG00000138246","Gene description":"DnaJ heat shock protein family (Hsp40) member C13","Uniprot":["O75165"],"Chromosome":"3","Position":"132417502-132539032","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Chaperone"],"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036923","HPA036924"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA036923":"AB_10672480","HPA036924":"AB_2675386"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"}},{"Gene":"DNAJC14","Gene synonym":["DNAJ","DRIP78","FLJ32792","HDJ3","LIP6"],"Ensembl":"ENSG00000135392","Gene description":"DnaJ heat shock protein family (Hsp40) member C14","Uniprot":["Q6Y2X3"],"Chromosome":"12","Position":"55820960-55830824","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Macrophages","Stomach - Macrophages","Testis - Spermatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017653"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017653":"AB_1847799"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"}},{"Gene":"DNAJC15","Gene synonym":["DNAJD1","MCJ"],"Ensembl":"ENSG00000120675","Gene description":"DnaJ heat shock protein family (Hsp40) member C15","Uniprot":["Q9Y5T4"],"Chromosome":"13","Position":"43023203-43114213","Protein class":["Disease related genes","Predicted membrane proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"496.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"}},{"Gene":"DNAJC16","Gene synonym":["KIAA0962"],"Ensembl":"ENSG00000116138","Gene description":"DnaJ heat shock protein family (Hsp40) member C16","Uniprot":["Q9Y2G8"],"Chromosome":"1","Position":"15526813-15592379","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043643"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA043643":"AB_10796794"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.77e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"}},{"Gene":"DNAJC18","Gene synonym":["MGC29463"],"Ensembl":"ENSG00000170464","Gene description":"DnaJ heat shock protein family (Hsp40) member C18","Uniprot":["Q9H819"],"Chromosome":"5","Position":"139408588-139444491","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"testis":"77.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Early spermatids":"447.7","Late spermatids":"1364.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"8.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Lung - Endothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036538","HPA060154"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA036538":"AB_10670802","HPA060154":"AB_2684212"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.89e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"}},{"Gene":"DNAJC22","Gene synonym":["FLJ13236","wus"],"Ensembl":"ENSG00000178401","Gene description":"DnaJ heat shock protein family (Hsp40) member C22","Uniprot":["Q8N4W6"],"Chromosome":"12","Position":"49346888-49357546","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"liver":"24.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"42.3","Distal enterocytes":"31.8","Enteroendocrine cells":"33.0","Hepatocytes":"38.5","Intestinal goblet cells":"31.8","Paneth cells":"34.1","Proximal enterocytes":"56.8","Thymic epithelial cells":"28.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enterocytes","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"midbrain":"1.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039953"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 26: NCI-H716 - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA039953":"AB_2676770"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.56e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.54e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"}},{"Gene":"DNAJC25","Gene synonym":["bA16L21.2.1"],"Ensembl":"ENSG00000059769","Gene description":"DnaJ heat shock protein family (Hsp40) member C25","Uniprot":["Q9H1X3"],"Chromosome":"9","Position":"111631334-111654351","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"32.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"74.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019122"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA019122":"AB_1853155"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.73e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"}},{"Gene":"DNAJC30","Gene synonym":["WBSCR18"],"Ensembl":"ENSG00000176410","Gene description":"DnaJ heat shock protein family (Hsp40) member C30","Uniprot":["Q96LL9"],"Chromosome":"7","Position":"73680918-73683453","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["ATP synthesis"],"Molecular function":["Chaperone"],"Disease involvement":["Disease variant","Leber hereditary optic neuropathy","Primary mitochondrial disease","Williams-Beuren syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"108.6","Late spermatids":"235.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017318"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017318":"AB_1858788"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.91e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"}},{"Gene":"DNAJC4","Gene synonym":["HSPF2","MCG18"],"Ensembl":"ENSG00000110011","Gene description":"DnaJ heat shock protein family (Hsp40) member C4","Uniprot":["Q9NNZ3"],"Chromosome":"11","Position":"64230278-64234286","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"240.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Late spermatids":"3377.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011947"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011947":"AB_1847803"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.12e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"}},{"Gene":"DNAJC5","Gene synonym":["CLN4","DNAJC5A","FLJ00118","FLJ13070"],"Ensembl":"ENSG00000101152","Gene description":"DnaJ heat shock protein family (Hsp40) member C5","Uniprot":["Q9H3Z4"],"Chromosome":"20","Position":"63895126-63936031","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"127.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012139","HPA012737","HPA013154"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA012139":null,"HPA012737":"AB_1847293","HPA013154":"AB_1847292"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.82e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.70e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"}},{"Gene":"DNAJC5B","Gene synonym":["CSP-beta","MGC26226"],"Ensembl":"ENSG00000147570","Gene description":"DnaJ heat shock protein family (Hsp40) member C5 beta","Uniprot":["Q9UF47"],"Chromosome":"8","Position":"66021553-66101245","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"testis":"65.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"131","RNA single cell type specific nTPM":{"Early spermatids":"767.4","Late spermatids":"2900.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"5.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"5.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"Leukemia":"1.7","lymphoma":"6.2","Myeloma":"3.2","Rhabdoid":"5.1"},"RNA tissue cell type enrichment":["Lung - Macrophages","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"}},{"Gene":"DNAJC5G","Gene synonym":["CSP-gamma","FLJ40417"],"Ensembl":"ENSG00000163793","Gene description":"DnaJ heat shock protein family (Hsp40) member C5 gamma","Uniprot":["Q8N7S2"],"Chromosome":"2","Position":"27275433-27281499","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"epididymis":"46.9","testis":"22.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"65.1","Late spermatids":"78.1","Spermatocytes":"78.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"2.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Heart muscle - Cardiomyocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041445"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041445":"AB_2677485"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"}},{"Gene":"DNASE1L1","Gene synonym":["DNAS1L1","DNASEX","DNL1L","XIB"],"Ensembl":"ENSG00000013563","Gene description":"Deoxyribonuclease 1 like 1","Uniprot":["P49184"],"Chromosome":"X","Position":"154401236-154412112","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Endonuclease","Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"147.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"48.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072635"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"96000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA072635":"AB_2686542"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"}},{"Gene":"DNASE1L2","Gene synonym":["DNAS1L2"],"Ensembl":"ENSG00000167968","Gene description":"Deoxyribonuclease 1 like 2","Uniprot":["Q92874"],"Chromosome":"16","Position":"2235816-2238711","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":["Endonuclease","Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"45.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"2.8","Cholangiocytes":"1.9","Enteroendocrine cells":"3.5","Excitatory neurons":"2.5","Inhibitory neurons":"2.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044714"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA044714":"AB_10962870"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-4"}},{"Gene":"DNER","Gene synonym":["bet","UNQ26"],"Ensembl":"ENSG00000187957","Gene description":"Delta\/notch like EGF repeat containing","Uniprot":["Q8NFT8"],"Chromosome":"2","Position":"229357629-229714555","Protein class":["Cancer-related genes","Predicted membrane proteins"],"Biological process":["Notch signaling pathway"],"Molecular function":["Activator","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"73.0","brain":"147.5","choroid plexus":"143.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"102.3","Horizontal cells":"169.8","Inhibitory neurons":"325.0","Oligodendrocyte precursor cells":"417.3","Oligodendrocytes":"233.8","Serous glandular cells":"199.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"32","RNA cancer specific FPKM":{"glioma":"73.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Skin - Eccrine sweat gland cells","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017320"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7900000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017320":"AB_1847808"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-3"}},{"Gene":"DNHD1","Gene synonym":["C11orf47","CCDC35","DHCD1","DKFZp686J0796","DNHD1L","FLJ32752","FLJ35709","FLJ46184"],"Ensembl":"ENSG00000179532","Gene description":"Dynein heavy chain domain 1","Uniprot":["Q96M86"],"Chromosome":"11","Position":"6497260-6593758","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"67.4","Excitatory neurons":"40.8","Inhibitory neurons":"32.0","Oligodendrocyte precursor cells":"34.7","Oligodendrocytes":"63.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039698","HPA040267","HPA057639"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA039698":"AB_10795111","HPA040267":"AB_2676913","HPA057639":"AB_2683486"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"}},{"Gene":"DNPEP","Gene synonym":["ASPEP","DAP"],"Ensembl":"ENSG00000123992","Gene description":"Aspartyl aminopeptidase","Uniprot":["Q9ULA0"],"Chromosome":"2","Position":"219372043-219400022","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Aminopeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"283.2","Late spermatids":"505.3","Proximal enterocytes":"221.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036398","HPA044860"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036398":"AB_10970915","HPA044860":"AB_10961275"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"}},{"Gene":"DOCK4","Gene synonym":["FLJ34238","KIAA0716"],"Ensembl":"ENSG00000128512","Gene description":"Dedicator of cytokinesis 4","Uniprot":["Q8N1I0"],"Chromosome":"7","Position":"111726110-112206407","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"41.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"766.4","Excitatory neurons":"415.9","Microglial cells":"1526.9","Oligodendrocyte precursor cells":"415.9","Oligodendrocytes":"769.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"2.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071516"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoli","Plasma membrane"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA071516":"AB_2686407"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"}},{"Gene":"DOK7","Gene synonym":["C4orf25","Dok-7","FLJ33718","FLJ39137"],"Ensembl":"ENSG00000175920","Gene description":"Docking protein 7","Uniprot":["Q18PE1"],"Chromosome":"4","Position":"3463306-3501473","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"41.9","skeletal muscle":"29.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"7.7","Basal prostatic cells":"6.4","Cardiomyocytes":"11.8","Late spermatids":"9.2","Skeletal myocytes":"8.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"11.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"memory B-cell":"3.4","naive B-cell":"2.3","NK-cell":"1.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"B-cells":"3.4","NK-cells":"1.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059449","HPA062780"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA059449":"AB_2684023","HPA062780":"AB_2732688"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.45e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.19e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.28e-4"}},{"Gene":"DOLK","Gene synonym":["DK1","KIAA1094","TMEM15"],"Ensembl":"ENSG00000175283","Gene description":"Dolichol kinase","Uniprot":["Q9UPQ8"],"Chromosome":"9","Position":"128945530-128947603","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"31.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066767","HPA068706"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA066767":"AB_2732751","HPA068706":"AB_2732118"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.53e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.88e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-3"}},{"Gene":"DOLPP1","Gene synonym":["LSFR2"],"Ensembl":"ENSG00000167130","Gene description":"Dolichyldiphosphatase 1","Uniprot":["Q86YN1"],"Chromosome":"9","Position":"129081111-129090438","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"40.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019179"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"HPA019179":"AB_1847827"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"}},{"Gene":"DONSON","Gene synonym":["B17","C21orf60","C2TA","DKFZP434M035"],"Ensembl":"ENSG00000159147","Gene description":"DNA replication fork stabilization factor DONSON","Uniprot":["Q9NYP3"],"Chromosome":"21","Position":"33559542-33588706","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"46.2","Erythroid cells":"37.7","Spermatocytes":"62.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039558","HPA049033"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm","Cell Junctions"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA039558":"AB_2676570","HPA049033":"AB_2680608"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.22e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"}},{"Gene":"DOP1A","Gene synonym":["dJ202D23.2","DOPEY1","KIAA1117"],"Ensembl":"ENSG00000083097","Gene description":"DOP1 leucine zipper like protein A","Uniprot":["Q5JWR5"],"Chromosome":"6","Position":"83067666-83171350","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"75.3","Excitatory neurons":"158.8","Inhibitory neurons":"144.6","Oligodendrocyte precursor cells":"135.3","Oligodendrocytes":"118.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027902","HPA027904"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA027902":"AB_10600003","HPA027904":"AB_10600877"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"}},{"Gene":"DOP1B","Gene synonym":["C21orf5","DOPEY2","KIAA0933"],"Ensembl":"ENSG00000142197","Gene description":"DOP1 leucine zipper like protein B","Uniprot":["Q9Y3R5"],"Chromosome":"21","Position":"36156782-36294274","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"62.8","Gastric mucus-secreting cells":"54.3","Intestinal goblet cells":"77.0","Prostatic glandular cells":"63.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"19.8"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Stomach - Gastric mucous cells","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072065"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA072065":"AB_2686486"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.08e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"}},{"Gene":"DPAGT1","Gene synonym":["ALG7","CDG-Ij","D11S366","DGPT","DPAGT","DPAGT2","GPT"],"Ensembl":"ENSG00000172269","Gene description":"Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1","Uniprot":["Q9H3H5"],"Chromosome":"11","Position":"119096503-119108331","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053878"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053878":"AB_2682288"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.03e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"}},{"Gene":"DPEP1","Gene synonym":[],"Ensembl":"ENSG00000015413","Gene description":"Dipeptidase 1","Uniprot":["P16444"],"Chromosome":"16","Position":"89613308-89638456","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Dipeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"intestine":"377.4","kidney":"255.9","pancreas":"440.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Peritubular cells":"1223.5","Proximal enterocytes":"4664.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"colorectal cancer":"107.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"colorectal cancer":"138.0"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Stomach - Gastric enteroendocrine cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009426","HPA012783"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nucleoplasm","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA009426":"AB_1847842","HPA012783":"AB_1847843"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.84e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"}},{"Gene":"DPEP2","Gene synonym":[],"Ensembl":"ENSG00000167261","Gene description":"Dipeptidase 2","Uniprot":["Q9H4A9"],"Chromosome":"16","Position":"67987394-68000586","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Dipeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"23.3","lymphoid tissue":"28.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"43.7","Kupffer cells":"39.4","Langerhans cells":"27.6","Macrophages":"32.8","monocytes":"57.2","Syncytiotrophoblasts":"68.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"410.0","eosinophil":"841.1","neutrophil":"358.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"841.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"6.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"12.3"},"Antibody":["HPA035644"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"330000000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035644":"AB_10670164"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.47e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"}},{"Gene":"DPEP3","Gene synonym":[],"Ensembl":"ENSG00000141096","Gene description":"Dipeptidase 3","Uniprot":["Q9H4B8"],"Chromosome":"16","Position":"67975663-67980549","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"testis":"47.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Spermatocytes":"338.8","Spermatogonia":"229.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"16.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"6.7","NK-cell":"1.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"6.7","NK-cells":"1.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"4.6","lymphoma":"5.8","Myeloma":"4.9","ovarian cancer":"6.8"},"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031870","HPA058607"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"27000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031870":"AB_2674079","HPA058607":"AB_2683775"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"}},{"Gene":"DPM1","Gene synonym":["CDGIE","MPDS"],"Ensembl":"ENSG00000000419","Gene description":"Dolichyl-phosphate mannosyltransferase subunit 1, catalytic","Uniprot":["O60762"],"Chromosome":"20","Position":"50934867-50958555","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Congenital muscular dystrophy","Disease variant","Dystroglycanopathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"238.3","Syncytiotrophoblasts":"268.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051818"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051818":"AB_2681624"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"}},{"Gene":"DPM2","Gene synonym":["MGC111193","MGC21559"],"Ensembl":"ENSG00000136908","Gene description":"Dolichyl-phosphate mannosyltransferase subunit 2, regulatory","Uniprot":["O94777"],"Chromosome":"9","Position":"127935099-127937854","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Congenital muscular dystrophy","Disease variant","Dystroglycanopathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064623"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064623":"AB_2685303"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.08e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"}},{"Gene":"DPM3","Gene synonym":["MGC125904","MGC125905","MGC34275"],"Ensembl":"ENSG00000179085","Gene description":"Dolichyl-phosphate mannosyltransferase subunit 3, regulatory","Uniprot":["Q9P2X0"],"Chromosome":"1","Position":"155139891-155140595","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Congenital muscular dystrophy","Disease variant","Dystroglycanopathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014667"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"290000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014667":"AB_1847848"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.09e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.97e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.64e-4"}},{"Gene":"DPP10","Gene synonym":["DPL2","DPPY","DPRP3"],"Ensembl":"ENSG00000175497","Gene description":"Dipeptidyl peptidase like 10","Uniprot":["Q8N608"],"Chromosome":"2","Position":"114442299-115845780","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Asthma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"10.7","brain":"20.2","pancreas":"17.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"4490.7","Excitatory neurons":"3021.7","Inhibitory neurons":"3211.6","Oligodendrocyte precursor cells":"948.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"lung cancer":"4.2","Rhabdoid":"10.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048767"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048767":"AB_2680515"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"}},{"Gene":"DPP6","Gene synonym":["DPL1","DPPX"],"Ensembl":"ENSG00000130226","Gene description":"Dipeptidyl peptidase like 6","Uniprot":["P42658"],"Chromosome":"7","Position":"153887097-154894285","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"54.0","endometrium 1":"58.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"664.4","Inhibitory neurons":"1169.8","Oligodendrocyte precursor cells":"1865.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"12.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"11.5"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Podocytes","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050509"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050509":"AB_2681150"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"}},{"Gene":"DPY19L1","Gene synonym":["KIAA0877"],"Ensembl":"ENSG00000173852","Gene description":"Dpy-19 like C-mannosyltransferase 1","Uniprot":["Q2PZI1"],"Chromosome":"7","Position":"34928876-35038271","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"66.5","Early spermatids":"124.5","Excitatory neurons":"130.7","Late spermatids":"110.8","Oligodendrocytes":"90.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059139"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059139":"AB_2683921"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.99e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"}},{"Gene":"DPY19L2","Gene synonym":["FLJ32949","SPATA34"],"Ensembl":"ENSG00000177990","Gene description":"Dpy-19 like 2","Uniprot":["Q6NUT2"],"Chromosome":"12","Position":"63558913-63668939","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein","Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"65.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"74.8","Excitatory neurons":"122.2","Inhibitory neurons":"134.2","Late spermatids":"138.3","Oligodendrocyte precursor cells":"118.9","Spermatocytes":"56.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skin - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071264","HPA078305"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA071264":"AB_2686375","HPA078305":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"DPY19L3","Gene synonym":[],"Ensembl":"ENSG00000178904","Gene description":"Dpy-19 like C-mannosyltransferase 3","Uniprot":["Q6ZPD9"],"Chromosome":"19","Position":"32405543-32485895","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"69.3","Oligodendrocyte precursor cells":"93.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008325"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA008325":"AB_1847853"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.55e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"}},{"Gene":"DPY19L4","Gene synonym":[],"Ensembl":"ENSG00000156162","Gene description":"Dpy-19 like 4","Uniprot":["Q7Z388"],"Chromosome":"8","Position":"94719703-94793836","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024339","HPA024780"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA024339":null,"HPA024780":"AB_10600869"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.73e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"}},{"Gene":"DRAM1","Gene synonym":["DRAM","FLJ11259"],"Ensembl":"ENSG00000136048","Gene description":"DNA damage regulated autophagy modulator 1","Uniprot":["Q8N682"],"Chromosome":"12","Position":"101877580-102012130","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"94.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"180.9","Early spermatids":"130.5","Late spermatids":"99.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.52e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"}},{"Gene":"DRAM2","Gene synonym":["MGC54289","PRO180","RP5-1180E21.1","TMEM77","WWFQ154"],"Ensembl":"ENSG00000156171","Gene description":"DNA damage regulated autophagy modulator 2","Uniprot":["Q6UX65"],"Chromosome":"1","Position":"111117163-111140203","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Autophagy"],"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"194.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018036","HPA061701"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA018036":"AB_1858134","HPA061701":"AB_2684590"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.45e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.43e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"}},{"Gene":"DRD1","Gene synonym":[],"Ensembl":"ENSG00000184845","Gene description":"Dopamine receptor D1","Uniprot":["P21728"],"Chromosome":"5","Position":"175440036-175444182","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"21.3","retina":"8.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Bipolar cells":"31.8","Horizontal cells":"42.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"21.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"1.3","Bone cancer":"1.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"basal ganglia":"164.4"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"13","RNA pig brain regional specific nTPM":{"basal ganglia":"86.7"},"Antibody":["HPA013393","HPA017304"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA013393":"AB_1847833","HPA017304":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"}},{"Gene":"DRD2","Gene synonym":[],"Ensembl":"ENSG00000149295","Gene description":"Dopamine receptor D2","Uniprot":["P14416"],"Chromosome":"11","Position":"113409605-113475691","Protein class":["FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"77.8","pituitary gland":"59.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"7.4","Horizontal cells":"16.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"77.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"7.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"10","RNA mouse brain regional specific nTPM":{"basal ganglia":"205.3"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"146.3"},"Antibody":["HPA015139","HPA015691"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015139":null,"HPA015691":"AB_1847834"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-3"}},{"Gene":"DRD3","Gene synonym":[],"Ensembl":"ENSG00000151577","Gene description":"Dopamine receptor D3","Uniprot":["P35462"],"Chromosome":"3","Position":"114127580-114199407","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets","Schizophrenia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"5.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"24.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"basal ganglia":"5.6","cerebral cortex":"2.8","hypothalamus":"4.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"7.4"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"10","RNA pig brain regional specific nTPM":{"basal ganglia":"17.9"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"DRD4","Gene synonym":[],"Ensembl":"ENSG00000069696","Gene description":"Dopamine receptor D4","Uniprot":["P21917"],"Chromosome":"11","Position":"637269-640706","Protein class":["FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":["Biological rhythms"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"152.5","Cone photoreceptor cells":"174.1","dendritic cells":"41.8","Rod photoreceptor cells":"172.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"3.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062682"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA062682":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"}},{"Gene":"DRD5","Gene synonym":["DRD1B","DRD1L2"],"Ensembl":"ENSG00000169676","Gene description":"Dopamine receptor D5","Uniprot":["P21918"],"Chromosome":"4","Position":"9781634-9784009","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Dystonia","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.6","stomach 1":"4.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1.1","Horizontal cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"thalamus":"7.0"},"Antibody":["HPA048930"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048930":"AB_2680562"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-3"}},{"Gene":"DRG2","Gene synonym":[],"Ensembl":"ENSG00000108591","Gene description":"Developmentally regulated GTP binding protein 2","Uniprot":["P55039"],"Chromosome":"17","Position":"18087892-18107970","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007716"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA007716":"AB_1078705"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.56e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.34e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"}},{"Gene":"DSC1","Gene synonym":["CDHF1"],"Ensembl":"ENSG00000134765","Gene description":"Desmocollin 1","Uniprot":["Q08554"],"Chromosome":"18","Position":"31129236-31162856","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"skin 1":"228.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Cardiomyocytes":"27.7","Suprabasal keratinocytes":"79.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"head and neck cancer":"7.3","melanoma":"4.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"naive CD4 T-cell":"2.7","naive CD8 T-cell":"2.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"T-cells":"2.7"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"ovarian cancer":"7.8"},"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Heart muscle - Cardiomyocytes","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075379"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"27000000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA075379":"AB_2732290"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-5"}},{"Gene":"DSC2","Gene synonym":["CDHF2","DSC3"],"Ensembl":"ENSG00000134755","Gene description":"Desmocollin 2","Uniprot":["Q02487"],"Chromosome":"18","Position":"31058840-31102522","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"164.0","vagina":"97.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"472.3","Squamous epithelial cells":"829.7","Suprabasal keratinocytes":"1514.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"48.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"eosinophil":"28.9","neutrophil":"8.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"granulocytes":"28.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"43.4"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skin - Outer root sheath cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011911","HPA012615"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA011911":"AB_1847618","HPA012615":"AB_1847619"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.80e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.01e-4"}},{"Gene":"DSC3","Gene synonym":["CDHF3","DSC","DSC1","DSC2","DSC4"],"Ensembl":"ENSG00000134762","Gene description":"Desmocollin 3","Uniprot":["Q14574"],"Chromosome":"18","Position":"30989365-31042815","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"99.2","skin 1":"372.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Basal keratinocytes":"528.1","Basal squamous epithelial cells":"320.1","Squamous epithelial cells":"413.8","Suprabasal keratinocytes":"609.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"78.6","head and neck cancer":"107.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bladder cancer":"20.3","cervical cancer":"32.0","Esophageal cancer":"41.6","Gallbladder cancer":"15.2","head and neck cancer":"59.1"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hippocampal formation":"3.3"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037328","HPA049265","HPA073937"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB037328":null,"HPA049265":"AB_2680695","HPA073937":"AB_2686645"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-5"}},{"Gene":"DSCAM","Gene synonym":["CHD2-42","CHD2-52"],"Ensembl":"ENSG00000171587","Gene description":"DS cell adhesion molecule","Uniprot":["O60469"],"Chromosome":"21","Position":"40010999-40847158","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Neurogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"6.6","pituitary gland":"4.2","retina":"1.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"1066.7","Oligodendrocyte precursor cells":"4191.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"glioma":"3.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"1.1"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Skin - Sebaceous gland cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019324","HPA057493"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA019324":"AB_2670118","HPA057493":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-3"}},{"Gene":"DSCAML1","Gene synonym":["KIAA1132"],"Ensembl":"ENSG00000177103","Gene description":"DS cell adhesion molecule like 1","Uniprot":["Q8TD84"],"Chromosome":"11","Position":"117427772-117817525","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Neurogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"27.0","retina":"20.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"81.1","Excitatory neurons":"175.9","Inhibitory neurons":"227.1","Oligodendrocyte precursor cells":"337.9","Oligodendrocytes":"439.2","Rod photoreceptor cells":"163.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.9","renal cancer":"2.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"4.5","Uterine cancer":"5.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035230"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035230":"AB_2674527"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.37e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"}},{"Gene":"DSE","Gene synonym":["DS-Epi1","DSEPI","SART2"],"Ensembl":"ENSG00000111817","Gene description":"Dermatan sulfate epimerase","Uniprot":["Q9UL01"],"Chromosome":"6","Position":"116254173-116444861","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":["Disease variant","Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"185.9","Late spermatids":"278.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"5.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014764"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014764":"AB_1856587"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.36e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.34e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"}},{"Gene":"DSEL","Gene synonym":["C18orf4","DE-epi2","FLJ11477","NCAG1"],"Ensembl":"ENSG00000171451","Gene description":"Dermatan sulfate epimerase like","Uniprot":["Q8IZU8"],"Chromosome":"18","Position":"67506587-67516720","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"83.2","Extravillous trophoblasts":"87.3","Oligodendrocyte precursor cells":"107.8","Oligodendrocytes":"98.3","Theca cells":"74.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"6.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060942"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA060942":"AB_2684392"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-4"}},{"Gene":"DSG2","Gene synonym":["CDHF5"],"Ensembl":"ENSG00000046604","Gene description":"Desmoglein 2","Uniprot":["Q14126"],"Chromosome":"18","Position":"31498177-31549008","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"105.3","parathyroid gland":"157.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"254.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"basophil":"8.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"8.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skeletal muscle - Endothelial cells","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004896","CAB025122"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB025122":null,"HPA004896":"AB_1078643"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.22e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.81e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.63e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.43e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.94e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.14e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"}},{"Gene":"DSG3","Gene synonym":["CDHF6"],"Ensembl":"ENSG00000134757","Gene description":"Desmoglein 3","Uniprot":["P32926"],"Chromosome":"18","Position":"31447741-31478702","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"313.9","vagina":"119.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Basal keratinocytes":"375.1","Basal squamous epithelial cells":"571.8","Squamous epithelial cells":"1104.2","Suprabasal keratinocytes":"709.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"104.0","head and neck cancer":"183.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"53","RNA blood cell specific nTPM":{"basophil":"8.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"82","RNA blood lineage specific nTPM":{"granulocytes":"8.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Esophageal cancer":"39.4","Gallbladder cancer":"45.8","head and neck cancer":"92.9"},"RNA tissue cell type enrichment":["Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046864","HPA056863","CAB069880"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB069880":"AB_2093604","HPA046864":"AB_2679846","HPA056863":"AB_2683260"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.43e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.90e-4"}},{"Gene":"DSG4","Gene synonym":["CDHF13","LAH"],"Ensembl":"ENSG00000175065","Gene description":"Desmoglein 4","Uniprot":["Q86SJ6"],"Chromosome":"18","Position":"31376777-31414912","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skin 1":"2.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1.7","Squamous epithelial cells":"1.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"colorectal cancer":"1.9"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059456","HPA079244"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059456":"AB_2684025","HPA079244":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"DST","Gene synonym":["BP240","BPA","BPAG1","CATX-15","FLJ13425","FLJ21489","FLJ30627","FLJ32235","KIAA0728","MACF2"],"Ensembl":"ENSG00000151914","Gene description":"Dystonin","Uniprot":["Q03001"],"Chromosome":"6","Position":"56457987-56954830","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Actin-binding","Muscle protein"],"Disease involvement":["Cancer-related genes","Epidermolysis bullosa","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"1882.1","Basal squamous epithelial cells":"1760.3","Cardiomyocytes":"1396.3","Oligodendrocytes":"1331.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Breast - Breast myoepithelial cells","Lung - Fibroblast_1","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030200"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm","Microtubules"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA030200":"AB_10601901"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"}},{"Gene":"DTNA","Gene synonym":["D18S892E","DRP3","DTN","DTN-1","DTN-2","DTN-3"],"Ensembl":"ENSG00000134769","Gene description":"Dystrobrevin alpha","Uniprot":["Q9Y4J8"],"Chromosome":"18","Position":"34493290-34891844","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"461.9","choroid plexus":"120.6","heart muscle":"150.0","skeletal muscle":"166.9","tongue":"209.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1701.5","Excitatory neurons":"498.6","Inhibitory neurons":"637.7","Oligodendrocyte precursor cells":"470.8","Oligodendrocytes":"346.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"28.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Smooth muscle cells","Prostate - Smooth muscle cells","Skeletal muscle - Skeletal myocytes","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015196","HPA071177"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Cell Junctions","Intermediate filaments"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB015196":"AB_2261797","HPA071177":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.64e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-5"}},{"Gene":"DTWD1","Gene synonym":["MDS009","MGC111207"],"Ensembl":"ENSG00000104047","Gene description":"DTW domain containing 1","Uniprot":["Q8N5C7"],"Chromosome":"15","Position":"49621037-49656232","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042214"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli rim","Mitotic chromosome","Vesicles"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Nucleoli rim"],"Subcellular additional location":["Nucleoplasm","Mitotic chromosome","Vesicles"],"Antibody RRID":{"HPA042214":"AB_2677903"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"}},{"Gene":"DTX2","Gene synonym":["KIAA1528","RNF58"],"Ensembl":"ENSG00000091073","Gene description":"Deltex E3 ubiquitin ligase 2","Uniprot":["Q86UW9"],"Chromosome":"7","Position":"76461676-76505995","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Notch signaling pathway","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"54.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"82.1","Ionocytes":"84.5","Respiratory ciliated cells":"60.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042931"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA042931":"AB_2678227"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.47e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"}},{"Gene":"DTYMK","Gene synonym":["CDC8","TMPK","TYMK"],"Ensembl":"ENSG00000168393","Gene description":"Deoxythymidylate kinase","Uniprot":["P23919"],"Chromosome":"2","Position":"241675747-241686944","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Nucleotide biosynthesis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"160.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Mitotic cells (Stomach)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042593","HPA042719"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA042593":"AB_10959590","HPA042719":"AB_10960633"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.22e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-2"}},{"Gene":"DUOX1","Gene synonym":["LNOX1","NOXEF1","THOX1"],"Ensembl":"ENSG00000137857","Gene description":"Dual oxidase 1","Uniprot":["Q9NRD9"],"Chromosome":"15","Position":"45129933-45165576","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hydrogen peroxide","Thyroid hormones biosynthesis"],"Molecular function":["Oxidoreductase","Peroxidase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"108.5","skin 1":"81.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"197.1","Alveolar cells type 2":"247.7","Glandular and luminal cells":"72.8","Respiratory ciliated cells":"73.0","Suprabasal keratinocytes":"84.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"32.4"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"12.4","white matter":"3.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bladder cancer":"6.1","cervical cancer":"13.2","Esophageal cancer":"9.4","Gallbladder cancer":"9.8","head and neck cancer":"15.3"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Lung - Alveolar cells type 2","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"cerebellum":"9.6"},"Antibody":["HPA023544"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023544":"AB_1847878"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.31e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"}},{"Gene":"DUOX2","Gene synonym":["LNOX2","P138-TOX","P138(TOX)","THOX2"],"Ensembl":"ENSG00000140279","Gene description":"Dual oxidase 2","Uniprot":["Q9NRD8"],"Chromosome":"15","Position":"45092650-45114172","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Hydrogen peroxide","Thyroid hormones biosynthesis"],"Molecular function":["Oxidoreductase","Peroxidase"],"Disease involvement":["Congenital hypothyroidism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"290.2","thyroid gland":"75.7","urinary bladder":"92.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Ductal cells":"252.8","Exocrine glandular cells":"324.2","Gastric mucus-secreting cells":"91.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"60.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bladder cancer":"1.1","cervical cancer":"3.5","Esophageal cancer":"2.2","head and neck cancer":"4.0"},"RNA tissue cell type enrichment":["Prostate - Urothelial cells","Stomach - Gastric mucous cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"1.2"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"}},{"Gene":"DUOXA1","Gene synonym":["FLJ32334","mol","NIP","NUMBIP"],"Ensembl":"ENSG00000140254","Gene description":"Dual oxidase maturation factor 1","Uniprot":["Q1HG43"],"Chromosome":"15","Position":"45117367-45129938","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"189.0","skin 1":"91.6","thyroid gland":"111.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"142.8","Alveolar cells type 2":"143.2","Glandular and luminal cells":"41.6","Squamous epithelial cells":"61.6","Suprabasal keratinocytes":"75.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"30.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bladder cancer":"9.6","cervical cancer":"15.6","Esophageal cancer":"11.7","head and neck cancer":"31.3"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041578"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041578":"AB_10795691"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"}},{"Gene":"DUOXA2","Gene synonym":[],"Ensembl":"ENSG00000140274","Gene description":"Dual oxidase maturation factor 2","Uniprot":["Q1HG44"],"Chromosome":"15","Position":"45114326-45118421","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital hypothyroidism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"63.9","urinary bladder":"41.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Ductal cells":"867.7","Exocrine glandular cells":"806.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"27.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063548"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063548":"AB_2685037"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"}},{"Gene":"DUS4L-BCAP29","Gene synonym":[],"Ensembl":"ENSG00000288558","Gene description":"DUS4L-BCAP29 readthrough","Uniprot":["Q9UHQ4"],"Chromosome":"7","Position":"107563971-107623317","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"5.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"5.8","monocytes":"1.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029215","HPA044301","HPA049694"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029215":"AB_10602331","HPA044301":"AB_10967460","HPA049694":"AB_2680854"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"DUSP13","Gene synonym":["BEDP","DUSP13A","DUSP13B","FLJ32450","TMDP"],"Ensembl":"ENSG00000079393","Gene description":"Dual specificity phosphatase 13","Uniprot":["Q6B8I1","Q9UII6"],"Chromosome":"10","Position":"75094432-75109221","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"247.2","testis":"53.7","tongue":"122.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Early spermatids":"377.6","Late spermatids":"167.7","Skeletal myocytes":"96.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"neutrophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"1.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"4.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"}},{"Gene":"DUSP3","Gene synonym":["VHR"],"Ensembl":"ENSG00000108861","Gene description":"Dual specificity phosphatase 3","Uniprot":["P51452"],"Chromosome":"17","Position":"43766125-43778977","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"261.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"326.4","Late spermatids":"176.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"33.5","granulocytes":"11.0","monocytes":"29.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063616"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA063616":"AB_2685061"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.00e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"}},{"Gene":"DYM","Gene synonym":["DMC","FLJ20071","SMC"],"Ensembl":"ENSG00000141627","Gene description":"Dymeclin","Uniprot":["Q7RTS9"],"Chromosome":"18","Position":"49036387-49461347","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"110.1","Early spermatids":"417.7","Excitatory neurons":"170.7","Inhibitory neurons":"199.5","Late spermatids":"175.2","Microglial cells":"145.9","Oligodendrocyte precursor cells":"160.8","Oligodendrocytes":"282.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043551","HPA049187"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA043551":"AB_2678547","HPA049187":"AB_2680668"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.26e-5"}},{"Gene":"DYNAP","Gene synonym":["C18orf26","FLJ39106"],"Ensembl":"ENSG00000178690","Gene description":"Dynactin associated protein","Uniprot":["Q8N1N2"],"Chromosome":"18","Position":"54587757-54599493","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"esophagus":"29.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Basal keratinocytes":"6.3","Serous glandular cells":"6.7","Suprabasal keratinocytes":"24.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011148"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011148":"AB_1845609"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"DYRK2","Gene synonym":[],"Ensembl":"ENSG00000127334","Gene description":"Dual specificity tyrosine phosphorylation regulated kinase 2","Uniprot":["Q92630"],"Chromosome":"12","Position":"67648338-67665406","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Ubl conjugation pathway"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"67.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027230","HPA056902"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA027230":"AB_1847925","HPA056902":"AB_2683271"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"}},{"Gene":"DYSF","Gene synonym":["FER1L1","LGMD2B"],"Ensembl":"ENSG00000135636","Gene description":"Dysferlin","Uniprot":["O75923"],"Chromosome":"2","Position":"71453722-71686768","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"95.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"27.6","Endothelial cells":"42.2","Excitatory neurons":"34.3","Oligodendrocytes":"59.1","Skeletal myocytes":"38.6","Syncytiotrophoblasts":"66.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"27.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"27.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Kidney - Endothelial cells","Lung - Neutrophil_2","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002510","HPA017071","HPA021945"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane","Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"CAB002510":"AB_442097","HPA017071":"AB_1847927","HPA021945":"AB_1847928"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"}},{"Gene":"DZIP3","Gene synonym":["hRUL138","PPP1R66"],"Ensembl":"ENSG00000198919","Gene description":"DAZ interacting zinc finger protein 3","Uniprot":["Q86Y13"],"Chromosome":"3","Position":"108589705-108694840","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["RNA-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"320.5","Excitatory neurons":"143.1","Respiratory ciliated cells":"163.4","Spermatocytes":"348.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035066","HPA049232"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035066":"AB_10601549","HPA049232":"AB_2680684"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.65e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"}},{"Gene":"E2F5","Gene synonym":[],"Ensembl":"ENSG00000133740","Gene description":"E2F transcription factor 5","Uniprot":["Q15329"],"Chromosome":"8","Position":"85177154-85217158","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Cilium biogenesis\/degradation","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"29.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"18.9","Plasma cells":"28.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"memory B-cell":"13.4","naive B-cell":"8.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"13.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055723","HPA065441"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Vesicles"],"Antibody RRID":{"HPA055723":"AB_2682897","HPA065441":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.89e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"}},{"Gene":"EBAG9","Gene synonym":["EB9","RCAS1"],"Ensembl":"ENSG00000147654","Gene description":"Estrogen receptor binding site associated antigen 9","Uniprot":["O00559"],"Chromosome":"8","Position":"109539711-109565996","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021153","HPA021154","CAB072810","CAB072811","CAB072812"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB072810":null,"CAB072811":null,"CAB072812":null,"HPA021153":"AB_1856151","HPA021154":"AB_1856152"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"}},{"Gene":"EBP","Gene synonym":["CDPX2","CHO2","CPX","CPXD"],"Ensembl":"ENSG00000147155","Gene description":"EBP cholestenol delta-isomerase","Uniprot":["Q15125"],"Chromosome":"X","Position":"48521799-48528716","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Isomerase"],"Disease involvement":["Cataract","Disease variant","Dwarfism","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"328.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"641.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Prostate - Prostate glandular cells","Skin - Sebaceous gland cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003130"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Nuclear membrane","Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA003130":"AB_1078717"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"EBPL","Gene synonym":["EBRP"],"Ensembl":"ENSG00000123179","Gene description":"EBP like","Uniprot":["Q9BY08"],"Chromosome":"13","Position":"49660674-49691486","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"99.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"303.3","Suprabasal keratinocytes":"273.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Liver - Hepatocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049891"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA049891":"AB_2680937"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.38e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.18e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"}},{"Gene":"ECE1","Gene synonym":["ECE"],"Ensembl":"ENSG00000117298","Gene description":"Endothelin converting enzyme 1","Uniprot":["P42892"],"Chromosome":"1","Position":"21217247-21345572","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Hirschsprung disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"163.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"29.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Lung - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001490","HPA013616"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001490":"AB_1078718","HPA013616":"AB_1847963"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"}},{"Gene":"ECE2","Gene synonym":["KIAA0604","MGC2408"],"Ensembl":"ENSG00000145194","Gene description":"Endothelin converting enzyme 2","Uniprot":["P0DPD6"],"Chromosome":"3","Position":"184276011-184293031","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Methyltransferase","Multifunctional enzyme","Protease","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"57.8","pancreas":"25.2","pituitary gland":"19.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Inhibitory neurons":"62.2","Oligodendrocyte precursor cells":"28.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"1.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.41e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.80e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"}},{"Gene":"ECEL1","Gene synonym":["DINE","XCE"],"Ensembl":"ENSG00000171551","Gene description":"Endothelin converting enzyme like 1","Uniprot":["O95672"],"Chromosome":"2","Position":"232479827-232487834","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"106.9","ovary":"99.7","pituitary gland":"27.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"31.6","Muller glia cells":"93.5","Peritubular cells":"20.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"12.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hypothalamus":"106.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"10.1","lung cancer":"6.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"70.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067560","HPA069756","HPA077424"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear membrane","Nucleoli"],"Antibody RRID":{"HPA067560":null,"HPA069756":null,"HPA077424":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"}},{"Gene":"ECHDC1","Gene synonym":["dJ351K20.2"],"Ensembl":"ENSG00000093144","Gene description":"Ethylmalonyl-CoA decarboxylase 1","Uniprot":["Q9NTX5"],"Chromosome":"6","Position":"127288712-127343609","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035445","HPA035446"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"56000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035445":"AB_10669860","HPA035446":"AB_2732468"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"}},{"Gene":"ECSCR","Gene synonym":["ARIA","ECSM2"],"Ensembl":"ENSG00000249751","Gene description":"Endothelial cell surface expressed chemotaxis and apoptosis regulator","Uniprot":["Q19T08"],"Chromosome":"5","Position":"139448560-139462743","Protein class":["Predicted membrane proteins"],"Biological process":["Angiogenesis","Apoptosis","Chemotaxis","Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Adipocytes":"242.8","Endothelial cells":"304.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"19.7","pancreatic cancer":"12.6"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Lung - Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skin - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063337"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA063337":"AB_2732701"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"}},{"Gene":"EDA","Gene synonym":["ED1","ED1-A1","ED1-A2","EDA-A1","EDA-A2","EDA1","EDA2","HED","ODT1","XHED","XLHED"],"Ensembl":"ENSG00000158813","Gene description":"Ectodysplasin A","Uniprot":["Q92838"],"Chromosome":"X","Position":"69616067-70039472","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"82.1","Oligodendrocyte precursor cells":"28.9","Oligodendrocytes":"43.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"1.2","MAIT T-cell":"1.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"1.2","T-cells":"1.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037972","HPA037973"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Lipid droplets"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":["Lipid droplets"],"Antibody RRID":{"HPA037972":"AB_2675761","HPA037973":"AB_2675762"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"}},{"Gene":"EDA2R","Gene synonym":["EDA-A2R","EDAA2R","TNFRSF27","XEDAR"],"Ensembl":"ENSG00000131080","Gene description":"Ectodysplasin A2 receptor","Uniprot":["Q9HAV5"],"Chromosome":"X","Position":"66595637-66639298","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Skeletal myocytes":"48.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"25.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054522"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA054522":"AB_2682516"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"}},{"Gene":"EDAR","Gene synonym":["DL","ED1R","ED3","ED5","EDA1R","EDA3"],"Ensembl":"ENSG00000135960","Gene description":"Ectodysplasin A receptor","Uniprot":["Q9UNE0"],"Chromosome":"2","Position":"108894471-108989372","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Differentiation"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"3.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"2.7","Squamous epithelial cells":"5.3","T-cells":"1.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"4.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"naive CD4 T-cell":"7.5","naive CD8 T-cell":"3.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"75","RNA blood lineage specific nTPM":{"T-cells":"7.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"10.5","Gastric cancer":"9.0"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042292"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042292":"AB_10794648"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-3"}},{"Gene":"EDNRA","Gene synonym":["ET-A","ETA-R","hET-AR"],"Ensembl":"ENSG00000151617","Gene description":"Endothelin receptor type A","Uniprot":["P25101"],"Chromosome":"4","Position":"147480917-147544954","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","FDA approved drug targets","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"seminal vesicle":"113.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"118.1","Leydig cells":"44.0","Peritubular cells":"68.2","Smooth muscle cells":"92.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Breast - Smooth muscle cells","Liver - Hepatic stellate cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013774","CAB018957"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB018957":"AB_2039838","HPA013774":"AB_1847994"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.50e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.93e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"}},{"Gene":"EDNRB","Gene synonym":["ETB","HSCR","HSCR2"],"Ensembl":"ENSG00000136160","Gene description":"Endothelin receptor type B","Uniprot":["P24530"],"Chromosome":"13","Position":"77895481-77975529","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Albinism","Deafness","Disease variant","FDA approved drug targets","Hirschsprung disease","Waardenburg syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"127.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"110.0","Astrocytes":"122.4","Endothelial cells":"80.0","Leydig cells":"83.6","Melanocytes":"175.9","Muller glia cells":"104.0","Sertoli cells":"105.0","Smooth muscle cells":"83.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"127.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Myeloma":"93.7","skin cancer":"125.5"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017842","HPA027546"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB017842":null,"HPA027546":"AB_2672327"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.20e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-3"}},{"Gene":"EDRF1","Gene synonym":["C10orf137","DKFZp586F1019","FLJ21617"],"Ensembl":"ENSG00000107938","Gene description":"Erythroid differentiation regulatory factor 1","Uniprot":["Q3B7T1"],"Chromosome":"10","Position":"125719515-125764143","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"112.2","Late spermatids":"90.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031820"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"HPA031820":"AB_10600753"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.16e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"}},{"Gene":"EEF1AKMT3","Gene synonym":["DKFZP586D0919","FAM119B","METTL21B"],"Ensembl":"ENSG00000123427","Gene description":"EEF1A lysine methyltransferase 3","Uniprot":["Q96AZ1"],"Chromosome":"12","Position":"57771492-57782541","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Late spermatids":"92.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043020","HPA045492"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitotic chromosome","Centrosome"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":["Nucleoplasm","Mitotic chromosome"],"Antibody RRID":{"HPA043020":"AB_2678274","HPA045492":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"EEF1AKMT4-ECE2","Gene synonym":[],"Ensembl":"ENSG00000284917","Gene description":"EEF1AKMT4-ECE2 readthrough","Uniprot":["P0DPD8"],"Chromosome":"3","Position":"184249695-184293031","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Methyltransferase","Multifunctional enzyme","Protease","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062215"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA062215":"AB_2684714"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"EEF1E1","Gene synonym":["AIMP3","P18"],"Ensembl":"ENSG00000124802","Gene description":"Eukaryotic translation elongation factor 1 epsilon 1","Uniprot":["O43324"],"Chromosome":"6","Position":"8073360-8102559","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"250.9","Proximal tubular cells":"193.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027901","HPA057866"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027901":"AB_10611960","HPA057866":"AB_2683547"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.16e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.24e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"}},{"Gene":"EEFSEC","Gene synonym":["EFSEC","SELB"],"Ensembl":"ENSG00000132394","Gene description":"Eukaryotic elongation factor, selenocysteine-tRNA specific","Uniprot":["P57772"],"Chromosome":"3","Position":"128153481-128408646","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"69.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035795"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA035795":"AB_10696512"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.98e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"}},{"Gene":"EFCAB14","Gene synonym":["KIAA0494"],"Ensembl":"ENSG00000159658","Gene description":"EF-hand calcium binding domain 14","Uniprot":["O75071"],"Chromosome":"1","Position":"46674659-46719146","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"159.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011224","HPA011938"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli","Golgi apparatus"],"Antibody RRID":{"HPA011224":"AB_1852314","HPA011938":"AB_1852317"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"}},{"Gene":"EFCAB8","Gene synonym":[],"Ensembl":"ENSG00000215529","Gene description":"EF-hand calcium binding domain 8","Uniprot":["A8MWE9"],"Chromosome":"20","Position":"32858923-32961609","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"testis":"3.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"2.9","Late spermatids":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034246","HPA042751"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034246":"AB_1565078","HPA042751":"AB_2678145"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-3"}},{"Gene":"EFL1","Gene synonym":["EFTUD1","FAM42A","FLJ13119","HsT19294","RIA1"],"Ensembl":"ENSG00000140598","Gene description":"Elongation factor like GTPase 1","Uniprot":["Q7Z2Z2"],"Chromosome":"15","Position":"82130233-82262734","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis","Ribosome biogenesis"],"Molecular function":["Elongation factor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"66.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039654","HPA047110","HPA052345"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039654":"AB_2676610","HPA047110":"AB_2797233","HPA052345":"AB_2681794"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.50e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"}},{"Gene":"EFNA1","Gene synonym":["ECKLG","EPLG1","GMAN","LERK1","TNFAIP4"],"Ensembl":"ENSG00000169242","Gene description":"Ephrin A1","Uniprot":["P20827"],"Chromosome":"1","Position":"155127876-155134899","Protein class":["Cancer-related genes","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Angiogenesis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"472.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"1145.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"naive CD4 T-cell":"11.4","naive CD8 T-cell":"5.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"T-cells":"11.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Lung - Alveolar cells type 1","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069549"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2800000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069549":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"EFNA2","Gene synonym":["ELF-1","EPLG6","LERK6"],"Ensembl":"ENSG00000099617","Gene description":"Ephrin A2","Uniprot":["O43921"],"Chromosome":"19","Position":"1285873-1301431","Protein class":["Cancer-related genes","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"12.3","liver":"12.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"21.2","Distal enterocytes":"54.5","Intestinal goblet cells":"20.8","Paneth cells":"32.9","Proximal enterocytes":"57.3","Undifferentiated cells":"19.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"11.5","stomach cancer":"8.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"8.1"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067567"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA067567":"AB_2732771"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"}},{"Gene":"EFNA3","Gene synonym":["Ehk1-L","EPLG3","LERK3"],"Ensembl":"ENSG00000143590","Gene description":"Ephrin A3","Uniprot":["P52797"],"Chromosome":"1","Position":"155078837-155087538","Protein class":["Predicted membrane proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"30.9","skin 1":"102.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"48.4","Basal squamous epithelial cells":"34.7","Extravillous trophoblasts":"34.5","Squamous epithelial cells":"31.3","Suprabasal keratinocytes":"95.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010494"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010494":"AB_2097783"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.46e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.66e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"}},{"Gene":"EFNA4","Gene synonym":["EPLG4","LERK4"],"Ensembl":"ENSG00000243364","Gene description":"Ephrin A4","Uniprot":["P52798"],"Chromosome":"1","Position":"155063737-155069553","Protein class":["Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"30.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"105.9","Theca cells":"57.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB021350"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB021350":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.00e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.60e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"}},{"Gene":"EFNA5","Gene synonym":["AF1","EPLG7","LERK7"],"Ensembl":"ENSG00000184349","Gene description":"Ephrin A5","Uniprot":["P52803"],"Chromosome":"5","Position":"107376894-107670937","Protein class":["Cancer-related genes","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Astrocytes":"282.2","Excitatory neurons":"786.9","Inhibitory neurons":"364.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013282","HPA054047"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB013282":"AB_2533353","HPA054047":"AB_2682355"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.92e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.77e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"}},{"Gene":"EFNB1","Gene synonym":["CFNS","Elk-L","EPLG2","LERK2"],"Ensembl":"ENSG00000090776","Gene description":"Ephrin B1","Uniprot":["P98172"],"Chromosome":"X","Position":"68829021-68842160","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes","Craniosynostosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"97.5","Basal squamous epithelial cells":"89.8","Extravillous trophoblasts":"87.5","Granulosa cells":"136.9","Theca cells":"92.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"3.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Kidney - Endothelial cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB031489","HPA067188"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB031489":"AB_631414","HPA067188":"AB_2685799"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.32e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.68e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.29e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"}},{"Gene":"EFNB2","Gene synonym":["EPLG5","Htk-L","HTKL","LERK5","MGC126226","MGC126227","MGC126228"],"Ensembl":"ENSG00000125266","Gene description":"Ephrin B2","Uniprot":["P52799"],"Chromosome":"13","Position":"106489745-106535662","Protein class":["Cancer-related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Differentiation","Host-virus interaction","Neurogenesis"],"Molecular function":["Developmental protein","Host cell receptor for virus entry","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"221.0","Endothelial cells":"159.6","Gastric mucus-secreting cells":"125.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Lung - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008999","CAB009368"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"940000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB009368":"AB_2095700","HPA008999":"AB_1078721"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.11e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.43e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.70e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-3"}},{"Gene":"EFNB3","Gene synonym":["EPLG8","LERK-8"],"Ensembl":"ENSG00000108947","Gene description":"Ephrin B3","Uniprot":["Q15768"],"Chromosome":"17","Position":"7705202-7711372","Protein class":["Cancer-related genes","Predicted membrane proteins"],"Biological process":["Differentiation","Host-virus interaction","Neurogenesis"],"Molecular function":["Developmental protein","Host cell receptor for virus entry","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"38.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"9.0","Respiratory ciliated cells":"8.5","Thymic epithelial cells":"17.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"15.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enteroendocrine cells","Liver - Hepatic stellate cells","Lung - Respiratory ciliated cells","Prostate - Prostate basal glandular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001623"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"11000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001623":"AB_1848026"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.52e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.21e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"}},{"Gene":"EGF","Gene synonym":[],"Ensembl":"ENSG00000138798","Gene description":"Epidermal growth factor","Uniprot":["P01133"],"Chromosome":"4","Position":"109912883-110013766","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"kidney":"110.2","pancreas":"89.5","skeletal muscle":"29.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"13.9","Exocrine glandular cells":"18.5","Muller glia cells":"23.3","Serous glandular cells":"15.7","Skeletal myocytes":"51.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Pancreas - Exocrine glandular cells","Prostate - Prostate glandular cells","Skin - Eccrine sweat gland cells","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":209000,"Blood concentration - Conc. blood MS [pg\/L]":"680000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"}},{"Gene":"EGFR","Gene synonym":["ERBB","ERBB1"],"Ensembl":"ENSG00000146648","Gene description":"Epidermal growth factor receptor","Uniprot":["P00533"],"Chromosome":"7","Position":"55019017-55211628","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Developmental protein","Host cell receptor for virus entry","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"281.0","Salivary duct cells":"238.8","Syncytiotrophoblasts":"433.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"136.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Prostate - Prostate basal glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000035","HPA001200","HPA018530","CAB068186","CAB073534"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":4740000,"Blood concentration - Conc. blood MS [pg\/L]":"88000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB000035":null,"CAB068186":"AB_2665679","CAB073534":null,"HPA001200":"AB_1078723","HPA018530":"AB_1848044"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.04e-5"}},{"Gene":"EI24","Gene synonym":["EPG4","PIG8","TP53I8"],"Ensembl":"ENSG00000149547","Gene description":"EI24 autophagy associated transmembrane protein","Uniprot":["O14681"],"Chromosome":"11","Position":"125569280-125584684","Protein class":["Cancer-related genes","Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Autophagy"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"461.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"532.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047165","HPA051029"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA047165":"AB_2679965","HPA051029":"AB_2681317"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.28e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"}},{"Gene":"EIF2AK3","Gene synonym":["PEK","PERK"],"Ensembl":"ENSG00000172071","Gene description":"Eukaryotic translation initiation factor 2 alpha kinase 3","Uniprot":["Q9NZJ5"],"Chromosome":"2","Position":"88556741-88627464","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Stress response","Translation regulation","Unfolded protein response"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"19.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"105.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"32.3"},"RNA tissue cell type enrichment":["Testis - Leydig cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009204","HPA015737"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009204":"AB_2230863","HPA015737":"AB_1848062"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"}},{"Gene":"EIF3E","Gene synonym":["eIF3-p48","EIF3S6","INT6"],"Ensembl":"ENSG00000104408","Gene description":"Eukaryotic translation initiation factor 3 subunit E","Uniprot":["P60228"],"Chromosome":"8","Position":"108162787-108443496","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Initiation factor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023973"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023973":"AB_1848083"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.06e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"}},{"Gene":"EIF3H","Gene synonym":["eIF3-gamma","eIF3-p40","EIF3S3"],"Ensembl":"ENSG00000147677","Gene description":"Eukaryotic translation initiation factor 3 subunit H","Uniprot":["O15372"],"Chromosome":"8","Position":"116642130-116766925","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Initiation factor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023117","HPA023553"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023117":"AB_1848076","HPA023553":"AB_1848077"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.26e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.07e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.34e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"}},{"Gene":"EIF3L","Gene synonym":["EIF3EIP","EIF3S11","EIF3S6IP","HSPC021","HSPC025"],"Ensembl":"ENSG00000100129","Gene description":"Eukaryotic translation initiation factor 3 subunit L","Uniprot":["Q9Y262"],"Chromosome":"22","Position":"37848868-37889407","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Initiation factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003028"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"72000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA003028":"AB_1078726"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-3"}},{"Gene":"EIF4E","Gene synonym":["EIF4E1","EIF4EL1","EIF4F"],"Ensembl":"ENSG00000151247","Gene description":"Eukaryotic translation initiation factor 4E","Uniprot":["P06730"],"Chromosome":"4","Position":"98879276-98929133","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Protein biosynthesis","Translation regulation"],"Molecular function":["Initiation factor","RNA-binding"],"Disease involvement":["Autism","Autism spectrum disorder","Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"894.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004077","CAB016316","HPA068358"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol","Cytoplasmic bodies"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB004077":"AB_823488","CAB016316":"AB_627502","HPA068358":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"}},{"Gene":"EIF5A","Gene synonym":["EIF-5A","EIF5A1","MGC104255","MGC99547"],"Ensembl":"ENSG00000132507","Gene description":"Eukaryotic translation initiation factor 5A","Uniprot":["P63241"],"Chromosome":"17","Position":"7306999-7312463","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":["Protein biosynthesis"],"Molecular function":["Elongation factor","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005042","HPA061298","HPA074052"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"CAB005042":"AB_562281","HPA061298":"AB_2684472","HPA074052":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.04e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.63e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"}},{"Gene":"EIPR1","Gene synonym":["EIPR-1","TSSC1"],"Ensembl":"ENSG00000032389","Gene description":"EARP complex and GARP complex interacting protein 1","Uniprot":["Q53HC9"],"Chromosome":"2","Position":"3188925-3377830","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031231","HPA031232","HPA031233","HPA031234"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"HPA031231":"AB_10669881","HPA031232":"AB_10603222","HPA031233":"AB_10670026","HPA031234":"AB_2673803"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.67e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"}},{"Gene":"ELAC1","Gene synonym":["D29"],"Ensembl":"ENSG00000141642","Gene description":"ElaC ribonuclease Z 1","Uniprot":["Q9H777"],"Chromosome":"18","Position":"50967991-50988121","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Endonuclease","Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040867","HPA066483"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA040867":"AB_10697716","HPA066483":"AB_2685675"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.43e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"}},{"Gene":"ELAPOR1","Gene synonym":["EIG121","KIAA1324","maba1"],"Ensembl":"ENSG00000116299","Gene description":"Endosome-lysosome associated apoptosis and autophagy regulator 1","Uniprot":["Q6UXG2"],"Chromosome":"1","Position":"109113679-109206781","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"156.7","salivary gland":"166.1","stomach 1":"88.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"128.8","Intestinal goblet cells":"145.3","Prostatic glandular cells":"361.6","Serous glandular cells":"221.5","Undifferentiated cells":"104.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"65.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"65.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"breast cancer":"35.1","colorectal cancer":"11.0","Gastric cancer":"11.3","lung cancer":"10.7","prostate cancer":"15.4"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Respiratory ciliated cells","Prostate - Prostate glandular cells","Skin - Eccrine sweat gland cells","Stomach - Chief cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029869","HPA070749"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA029869":"AB_10794320","HPA070749":"AB_2686304"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.14e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.69e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.16e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"}},{"Gene":"ELAPOR2","Gene synonym":["EIG121L","FLJ31340","KIAA1324L"],"Ensembl":"ENSG00000164659","Gene description":"Endosome-lysosome associated apoptosis and autophagy regulator family member 2","Uniprot":["A8MWY0"],"Chromosome":"7","Position":"86876906-87059654","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"51.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"69.0","Early spermatids":"88.0","Excitatory neurons":"56.5","Inhibitory neurons":"106.6","Late spermatids":"98.8","Oligodendrocytes":"363.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"1.9","NK-cells":"2.3","T-cells":"2.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"33.8"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044527","HPA076093"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA044527":"AB_10963793","HPA076093":"AB_2686776"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"ELFN1","Gene synonym":["PPP1R28"],"Ensembl":"ENSG00000225968","Gene description":"Extracellular leucine rich repeat and fibronectin type III domain containing 1","Uniprot":["P0C7U0"],"Chromosome":"7","Position":"1688119-1747954","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Protein phosphatase inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"7.2","liver":"14.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"17.2","Endothelial cells":"5.8","Hepatocytes":"10.7","Inhibitory neurons":"18.7","Rod photoreceptor cells":"6.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"9.6","Sarcoma":"14.1"},"RNA tissue cell type enrichment":["Colon - Endothelial cells","Liver - Hepatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066382"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"43000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA066382":"AB_2732744"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.68e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"}},{"Gene":"ELFN2","Gene synonym":["dJ63G5.3","KIAA1904","LRRC62","PPP1R29"],"Ensembl":"ENSG00000166897","Gene description":"Extracellular leucine rich repeat and fibronectin type III domain containing 2","Uniprot":["Q5R3F8"],"Chromosome":"22","Position":"37367960-37427479","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Protein phosphatase inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"18.2","retina":"6.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"40.9","Excitatory neurons":"11.4","Horizontal cells":"12.2","Inhibitory neurons":"15.8","Oligodendrocyte precursor cells":"35.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"amygdala":"18.2","basal ganglia":"13.8","cerebral cortex":"17.5","hippocampal formation":"16.6","white matter":"4.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000781"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA000781":"AB_1079280"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"}},{"Gene":"ELMOD1","Gene synonym":["DKFZp547C176"],"Ensembl":"ENSG00000110675","Gene description":"ELMO domain containing 1","Uniprot":["Q8N336"],"Chromosome":"11","Position":"107591091-107666779","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"32.8","pituitary gland":"21.7","retina":"32.6","skin 1":"28.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"27.8","Excitatory neurons":"124.4","Horizontal cells":"30.8","Inhibitory neurons":"101.5","Oligodendrocyte precursor cells":"77.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"glioma":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"25.3"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066479"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA066479":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"}},{"Gene":"ELOB","Gene synonym":["SIII","TCEB2"],"Ensembl":"ENSG00000103363","Gene description":"Elongin B","Uniprot":["Q15370"],"Chromosome":"16","Position":"2771414-2777280","Protein class":["Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"6800.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064006"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"82000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064006":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"}},{"Gene":"ELOVL1","Gene synonym":["Ssc1"],"Ensembl":"ENSG00000066322","Gene description":"ELOVL fatty acid elongase 1","Uniprot":["Q9BW60"],"Chromosome":"1","Position":"43363398-43368074","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033426","HPA056557"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB033426":"AB_2099896","HPA056557":"AB_2683173"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.63e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.79e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.51e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"}},{"Gene":"ELOVL2","Gene synonym":["Ssc2"],"Ensembl":"ENSG00000197977","Gene description":"ELOVL fatty acid elongase 2","Uniprot":["Q9NXB9"],"Chromosome":"6","Position":"10980759-11044305","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"52.5","placenta":"35.3","retina":"27.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"92.0","Cone photoreceptor cells":"51.7","Extravillous trophoblasts":"22.2","Spermatocytes":"22.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"breast cancer":"11.9","glioma":"25.8","liver cancer":"24.0","melanoma":"14.2","prostate cancer":"9.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"27.0"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Fibroblast_2","Prostate - Prostate glandular cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.73e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"}},{"Gene":"ELOVL3","Gene synonym":["CIG-30"],"Ensembl":"ENSG00000119915","Gene description":"ELOVL fatty acid elongase 3","Uniprot":["Q9HB03"],"Chromosome":"10","Position":"102226299-102229589","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"skin 1":"30.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"2.7","Breast myoepithelial cells":"3.5","Kupffer cells":"1.9","Spermatogonia":"4.3","Theca cells":"1.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"10.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"classical monocyte":"7.1","intermediate monocyte":"2.4","myeloid DC":"2.0","non-classical monocyte":"5.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"2.0","monocytes":"7.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"7.3"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036236"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036236":"AB_10601550"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.25e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"ELOVL4","Gene synonym":["CT118","SCA34","STGD2","STGD3"],"Ensembl":"ENSG00000118402","Gene description":"ELOVL fatty acid elongase 4","Uniprot":["Q9GZR5"],"Chromosome":"6","Position":"79914814-79947553","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","FDA approved drug targets","Ichthyosis","Intellectual disability","Neurodegeneration","Spinocerebellar ataxia","Stargardt disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"105.5","retina":"176.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"89.5","Cone photoreceptor cells":"274.0","Rod photoreceptor cells":"312.7","Suprabasal keratinocytes":"89.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"MAIT T-cell":"23.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"238","RNA blood lineage specific nTPM":{"T-cells":"23.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"18.1"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Kidney - Podocytes","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.27e-4"}},{"Gene":"ELOVL5","Gene synonym":["dJ483K16.1","HELO1","SCA38"],"Ensembl":"ENSG00000012660","Gene description":"ELOVL fatty acid elongase 5","Uniprot":["Q9NYP7"],"Chromosome":"6","Position":"53267398-53349179","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"305.1","Prostatic glandular cells":"270.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Skeletal muscle - Endothelial cells","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017042","HPA047752","HPA054197"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB017042":null,"HPA047752":"AB_2680147","HPA054197":"AB_2682413"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.80e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"}},{"Gene":"ELOVL6","Gene synonym":["FLJ23378","LCE","MGC5487"],"Ensembl":"ENSG00000170522","Gene description":"ELOVL fatty acid elongase 6","Uniprot":["Q9H5J4"],"Chromosome":"4","Position":"110045846-110199199","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"36.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"82.3","Hepatocytes":"90.8","Inhibitory neurons":"76.7","Oligodendrocytes":"73.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"gdT-cell":"2.4","MAIT T-cell":"2.6","memory CD4 T-cell":"1.0","memory CD8 T-cell":"1.3","naive CD8 T-cell":"1.0","NK-cell":"3.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"NK-cells":"3.3","T-cells":"2.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042355"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042355":"AB_10796577"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.74e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"}},{"Gene":"ELOVL7","Gene synonym":["FLJ23563"],"Ensembl":"ENSG00000164181","Gene description":"ELOVL fatty acid elongase 7","Uniprot":["A1L3X0"],"Chromosome":"5","Position":"60751791-60844274","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Microglial cells":"185.2","Oligodendrocytes":"85.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"1.9","neutrophil":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"granulocytes":"1.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Cholangiocyte","Skeletal muscle - Endothelial cells","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036337"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036337":"AB_10670797"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.87e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.54e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-3"}},{"Gene":"EMB","Gene synonym":["MGC71745"],"Ensembl":"ENSG00000170571","Gene description":"Embigin","Uniprot":["Q6PCB8"],"Chromosome":"5","Position":"50396192-50443248","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"152.5","intestine":"72.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"116.5","Macrophages":"105.3","NK-cells":"159.4","Proximal enterocytes":"128.9","T-cells":"151.7","Thymic epithelial cells":"106.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Mesothelial cells","Heart muscle - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.76e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-3"}},{"Gene":"EMC1","Gene synonym":["KIAA0090"],"Ensembl":"ENSG00000127463","Gene description":"ER membrane protein complex subunit 1","Uniprot":["Q8N766"],"Chromosome":"1","Position":"19215660-19251527","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"58.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048904"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048904":"AB_2680552"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.56e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.43e-4"}},{"Gene":"EMC10","Gene synonym":["C19orf63","HSM1","HSS1","INM02"],"Ensembl":"ENSG00000161671","Gene description":"ER membrane protein complex subunit 10","Uniprot":["Q5UCC4"],"Chromosome":"19","Position":"50476400-50490871","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Angiogenesis"],"Molecular function":null,"Disease involvement":["Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"185.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"634.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053905","HPA062723"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053905":"AB_2682303","HPA062723":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.39e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.64e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"}},{"Gene":"EMC3","Gene synonym":["TMEM111"],"Ensembl":"ENSG00000125037","Gene description":"ER membrane protein complex subunit 3","Uniprot":["Q9P0I2"],"Chromosome":"3","Position":"9962537-10011116","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"351.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042372"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042372":"AB_10795609"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.81e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"}},{"Gene":"EMC4","Gene synonym":["FLJ90746","MGC24415","PIG17","TMEM85"],"Ensembl":"ENSG00000128463","Gene description":"ER membrane protein complex subunit 4","Uniprot":["Q5J8M3"],"Chromosome":"15","Position":"34225013-34230156","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053440"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053440":"AB_2682151"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"}},{"Gene":"EMC6","Gene synonym":["MGC2963","RAB5IFL","TMEM93"],"Ensembl":"ENSG00000127774","Gene description":"ER membrane protein complex subunit 6","Uniprot":["Q9BV81"],"Chromosome":"17","Position":"3668812-3669668","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"185.0"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062681"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Centrosome"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA062681":"AB_2684831"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.73e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.39e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"}},{"Gene":"EMC7","Gene synonym":["C11orf3","C15orf24"],"Ensembl":"ENSG00000134153","Gene description":"ER membrane protein complex subunit 7","Uniprot":["Q9NPA0"],"Chromosome":"15","Position":"34084017-34101862","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010029"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010029":"AB_1078335"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.68e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.25e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-3"}},{"Gene":"EMCN","Gene synonym":["MUC14"],"Ensembl":"ENSG00000164035","Gene description":"Endomucin","Uniprot":["Q9ULC0"],"Chromosome":"4","Position":"100395341-100880126","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Adipocytes":"399.6","Endothelial cells":"248.1","Microglial cells":"108.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Colon - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Skin - Endothelial cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005928"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"470000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA005928":"AB_1078735"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"}},{"Gene":"EMD","Gene synonym":["LEMD5","STA"],"Ensembl":"ENSG00000102119","Gene description":"Emerin","Uniprot":["P50402"],"Chromosome":"X","Position":"154379273-154381523","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Cardiomyopathy","Disease variant","Emery-Dreifuss muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000609","CAB001545","CAB002029","CAB058694","CAB062552"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear membrane","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"CAB001545":"AB_2100047","CAB002029":"AB_442088","CAB058694":"AB_2665587","CAB062552":"AB_2665586","HPA000609":"AB_1078736"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"}},{"Gene":"EMP1","Gene synonym":["CL-20","TMP"],"Ensembl":"ENSG00000134531","Gene description":"Epithelial membrane protein 1","Uniprot":["P54849"],"Chromosome":"12","Position":"13196723-13219941","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"2255.1","vagina":"819.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"811.4","Basal keratinocytes":"635.2","Endothelial cells":"499.2","Squamous epithelial cells":"933.1","Suprabasal keratinocytes":"1153.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"myeloid DC":"3.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"dendritic cells":"3.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"567.9"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"midbrain":"4.5","spinal cord":"16.0"},"Antibody":["HPA046912"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046912":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-8"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.46e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.69e-8"}},{"Gene":"EMP2","Gene synonym":["XMP"],"Ensembl":"ENSG00000213853","Gene description":"Epithelial membrane protein 2","Uniprot":["P54851"],"Chromosome":"16","Position":"10528422-10580632","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"230.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 1":"3455.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Liver - Hepatocytes","Lung - Alveolar cells type 1","Skeletal muscle - Endothelial cells","Skin - Keratinocyte (other)","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014711","HPA070816"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA014711":"AB_1848147","HPA070816":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.23e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.85e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"}},{"Gene":"EMP3","Gene synonym":["YMP"],"Ensembl":"ENSG00000142227","Gene description":"Epithelial membrane protein 3","Uniprot":["P54852"],"Chromosome":"19","Position":"48321509-48330553","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"774.7","Hofbauer cells":"898.0","Langerhans cells":"2220.9","Macrophages":"697.4","Melanocytes":"1260.9","monocytes":"1112.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"195.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062030"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA062030":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.31e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"}},{"Gene":"ENDOD1","Gene synonym":["KIAA0830"],"Ensembl":"ENSG00000149218","Gene description":"Endonuclease domain containing 1","Uniprot":["O94919"],"Chromosome":"11","Position":"95089846-95132645","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Endonuclease","Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"94.6","Oligodendrocytes":"116.0","Schwann cells":"111.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008932","HPA010517"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5200000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA008932":"AB_2262252","HPA010517":"AB_1852351"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.86e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.64e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.27e-4"}},{"Gene":"ENG","Gene synonym":["CD105","END","HHT1","ORW","ORW1"],"Ensembl":"ENSG00000106991","Gene description":"Endoglin","Uniprot":["P17813"],"Chromosome":"9","Position":"127815013-127854658","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"528.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"410.1","Endothelial cells":"499.4","Extravillous trophoblasts":"345.1","Leydig cells":"482.7","Peritubular cells":"1389.9","Syncytiotrophoblasts":"477.6","Theca cells":"287.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"19.9","intermediate monocyte":"28.2","myeloid DC":"10.3","NK-cell":"7.6","non-classical monocyte":"22.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"10.3","monocytes":"28.2","NK-cells":"7.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Prostate - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000096","HPA011862","HPA067440","CAB072873"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB000096":"AB_563482","CAB072873":"AB_2665725","HPA011862":"AB_1846217","HPA067440":"AB_2685840"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.61e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.62e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.26e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"}},{"Gene":"ENHO","Gene synonym":["C9orf165","UNQ470"],"Ensembl":"ENSG00000168913","Gene description":"Energy homeostasis associated","Uniprot":["Q6UWT2"],"Chromosome":"9","Position":"34521043-34522990","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"brain":"475.8","choroid plexus":"256.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"69.0","monocytes":"37.8","Muller glia cells":"136.0","Prostatic glandular cells":"66.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"44.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"myeloid DC":"28.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"28.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"10.3"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042575"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":4240000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042575":"AB_10794914"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.71e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"}},{"Gene":"ENOSF1","Gene synonym":["FUCD","HSRTSBETA","rTS","TYMSAS"],"Ensembl":"ENSG00000132199","Gene description":"Enolase superfamily member 1","Uniprot":["Q7L5Y1"],"Chromosome":"18","Position":"670318-712662","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase","Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"187.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047829"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7300","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047829":"AB_2680170"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.27e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"}},{"Gene":"ENPEP","Gene synonym":["CD249","gp160"],"Ensembl":"ENSG00000138792","Gene description":"Glutamyl aminopeptidase","Uniprot":["Q07075"],"Chromosome":"4","Position":"110365733-110565285","Protein class":["CD markers","Enzymes","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Aminopeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"163.6","kidney":"90.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"607.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"renal cancer":"41.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"5.5","Kidney cancer":"12.5","testis cancer":"5.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005128"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA005128":"AB_1844795"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"}},{"Gene":"ENPP1","Gene synonym":["M6S1","NPPS","PC-1","PCA1","PDNP1"],"Ensembl":"ENSG00000197594","Gene description":"Ectonucleotide pyrophosphatase\/phosphodiesterase 1","Uniprot":["P22413"],"Chromosome":"6","Position":"131808016-131895155","Protein class":["CD markers","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Biomineralization"],"Molecular function":["Hydrolase"],"Disease involvement":["Diabetes mellitus","Disease variant","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"44.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"103.3","Endometrial stromal cells":"80.0","Hepatocytes":"96.3","Peritubular cells":"71.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032904","HPA062066"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4400000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB032904":"AB_2099635","HPA062066":"AB_2684674"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"}},{"Gene":"ENPP2","Gene synonym":["ATX","PD-IALPHA","PDNP2"],"Ensembl":"ENSG00000136960","Gene description":"Ectonucleotide pyrophosphatase\/phosphodiesterase 2","Uniprot":["Q13822"],"Chromosome":"8","Position":"119557086-119673453","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Chemotaxis","Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"383.3","choroid plexus":"753.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"983.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"46.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"53.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"53.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"83.4"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023700","HPA053652"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Actin filaments"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA023700":"AB_1848170","HPA053652":"AB_2682218"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.07e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"}},{"Gene":"ENPP3","Gene synonym":["B10","CD203c","gp130RB13-6","PD-IBETA","PDNP3"],"Ensembl":"ENSG00000154269","Gene description":"Ectonucleotide pyrophosphatase\/phosphodiesterase 3","Uniprot":["O14638"],"Chromosome":"6","Position":"131628442-131747418","Protein class":["CD markers","Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"32.1","intestine":"44.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Basal prostatic cells":"246.4","Endometrial ciliated cells":"137.5","Glandular and luminal cells":"373.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"renal cancer":"49.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"86","RNA blood cell specific nTPM":{"basophil":"30.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"86","RNA blood lineage specific nTPM":{"granulocytes":"30.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"4.4","Leukemia":"6.4"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes","Lung - Mast cells","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"spinal cord":"2.6"},"Antibody":["HPA043772"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043772":"AB_10795616"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"}},{"Gene":"ENPP4","Gene synonym":["AP3Aase","KIAA0879","NPP4"],"Ensembl":"ENSG00000001561","Gene description":"Ectonucleotide pyrophosphatase\/phosphodiesterase 4","Uniprot":["Q9Y6X5"],"Chromosome":"6","Position":"46129989-46146688","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"96.3","dendritic cells":"71.2","Oligodendrocytes":"118.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016594"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016594":"AB_1848171"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.95e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"}},{"Gene":"ENPP5","Gene synonym":[],"Ensembl":"ENSG00000112796","Gene description":"Ectonucleotide pyrophosphatase\/phosphodiesterase family member 5","Uniprot":["Q9UJA9"],"Chromosome":"6","Position":"46159185-46170980","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"epididymis":"243.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"44.6","Muller glia cells":"79.8","Prostatic glandular cells":"52.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"14.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"14.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Eccrine sweat gland cells","Stomach - Parietal cells","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016902"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"620000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA016902":"AB_1848172"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.57e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.04e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.44e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"}},{"Gene":"ENPP6","Gene synonym":["MGC33971"],"Ensembl":"ENSG00000164303","Gene description":"Ectonucleotide pyrophosphatase\/phosphodiesterase 6","Uniprot":["Q6UWR7"],"Chromosome":"4","Position":"184088706-184221230","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"29.4","kidney":"30.6","ovary":"12.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"113.1","Peritubular cells":"34.5","Proximal tubular cells":"20.8","Theca cells":"26.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"3.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"1.6"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Skeletal muscle - Fibroblasts","Testis - Peritubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042740","HPA069197"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"290000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA042740":"AB_10793984","HPA069197":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"}},{"Gene":"ENPP7","Gene synonym":["alk-SMase","NPP7"],"Ensembl":"ENSG00000182156","Gene description":"Ectonucleotide pyrophosphatase\/phosphodiesterase 7","Uniprot":["Q6UWV6"],"Chromosome":"17","Position":"79730943-79742219","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"intestine":"104.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"25","RNA single cell type specific nTPM":{"Hepatocytes":"7.9","Proximal enterocytes":"28.1","Proximal tubular cells":"8.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"liver cancer":"6.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"1.6"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024603"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024603":"AB_1848174"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"}},{"Gene":"ENSA","Gene synonym":["ARPP-19e","MGC4319","MGC78563","MGC8394"],"Ensembl":"ENSG00000143420","Gene description":"Endosulfine alpha","Uniprot":["O43768"],"Chromosome":"1","Position":"150600851-150629612","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Protein phosphatase inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051294"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"700000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Microtubules","Cytosol"],"Antibody RRID":{"HPA051294":"AB_2681425"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.24e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-3"}},{"Gene":"ENTPD1","Gene synonym":["ATPDase","CD39","NTPDase-1","SPG64"],"Ensembl":"ENSG00000138185","Gene description":"Ectonucleoside triphosphate diphosphohydrolase 1","Uniprot":["P49961"],"Chromosome":"10","Position":"95711779-95877266","Protein class":["CD markers","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"71.8","Endothelial cells":"64.7","Langerhans cells":"145.4","Macrophages":"64.2","Microglial cells":"211.6","Plasma cells":"90.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"17.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"102.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"31.9","granulocytes":"102.2","monocytes":"41.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002494","HPA014067","CAB079986"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB002494":"AB_563557","CAB079986":null,"HPA014067":"AB_1848178"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.33e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.89e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"}},{"Gene":"ENTPD2","Gene synonym":["CD39L1","NTPDase-2"],"Ensembl":"ENSG00000054179","Gene description":"Ectonucleoside triphosphate diphosphohydrolase 2","Uniprot":["Q9Y5L3"],"Chromosome":"9","Position":"137048107-137054061","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"31.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"201.3","Peritubular cells":"93.3","Proximal enterocytes":"59.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"15.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017676"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017676":"AB_1848179"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.51e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.38e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"}},{"Gene":"ENTPD3","Gene synonym":["CD39L3","HB6","NTPDase-3"],"Ensembl":"ENSG00000168032","Gene description":"Ectonucleoside triphosphate diphosphohydrolase 3","Uniprot":["O75355"],"Chromosome":"3","Position":"40387184-40428744","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"20.8","cervix":"21.3","salivary gland":"22.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Inhibitory neurons":"90.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"plasmacytoid DC":"3.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"3.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"18.0","Neuroblastoma":"11.3"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"ENTPD4","Gene synonym":["KIAA0392","LALP70","LAP70","LYSAL1","NTPDase-4","UDPase"],"Ensembl":"ENSG00000197217","Gene description":"Ectonucleoside triphosphate diphosphohydrolase 4","Uniprot":["Q9Y227"],"Chromosome":"8","Position":"23385783-23457695","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017655"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"82000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA017655":"AB_1848181"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"}},{"Gene":"ENTPD6","Gene synonym":["CD39L2","dJ738P15.3","IL6ST2","NTPDase-6"],"Ensembl":"ENSG00000197586","Gene description":"Ectonucleoside triphosphate diphosphohydrolase 6","Uniprot":["O75354"],"Chromosome":"20","Position":"25195693-25228075","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015491","HPA069555"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"41000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA015491":"AB_2669200","HPA069555":"AB_2686152"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"}},{"Gene":"ENTPD7","Gene synonym":["FLJ30978","LALP1"],"Ensembl":"ENSG00000198018","Gene description":"Ectonucleoside triphosphate diphosphohydrolase 7","Uniprot":["Q9NQZ7"],"Chromosome":"10","Position":"99659509-99711241","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"14.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"dendritic cells":"200.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014351"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"65000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA014351":"AB_1848183"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"}},{"Gene":"ENTPD8","Gene synonym":["NTPDase-8","UNQ2492"],"Ensembl":"ENSG00000188833","Gene description":"Ectonucleoside triphosphate diphosphohydrolase 8","Uniprot":["Q5MY95"],"Chromosome":"9","Position":"137434364-137441816","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"27.6","liver":"14.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Distal enterocytes":"98.6","Intestinal goblet cells":"213.2","Paneth cells":"60.5","Proximal enterocytes":"150.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"5.5","Gastric cancer":"5.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021509"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA021509":"AB_1848185"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.17e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"}},{"Gene":"EOGT","Gene synonym":["AER61","C3orf64","FLJ33770"],"Ensembl":"ENSG00000163378","Gene description":"EGF domain specific O-linked N-acetylglucosamine transferase","Uniprot":["Q5NDL2"],"Chromosome":"3","Position":"68975217-69013684","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"50.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019460"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA019460":"AB_1844628"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.97e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"}},{"Gene":"EPB41","Gene synonym":["4.1R","EL1"],"Ensembl":"ENSG00000159023","Gene description":"Erythrocyte membrane protein band 4.1","Uniprot":["P11171"],"Chromosome":"1","Position":"28887091-29120046","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell cycle","Cell division","Mitosis","Transport"],"Molecular function":["Actin-binding","Calmodulin-binding"],"Disease involvement":["Elliptocytosis","Hereditary hemolytic anemia","Pyropoikilocytosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"80.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"243.3","Cone photoreceptor cells":"229.2","Rod photoreceptor cells":"370.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"42.2"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"104.3"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"cerebellum":"105.6"},"Antibody":["HPA028076","HPA028096","HPA028412","HPA028414"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Plasma membrane","Cell Junctions","Cytokinetic bridge","Mitotic spindle","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nuclear bodies","Cytokinetic bridge","Mitotic spindle","Cytosol"],"Antibody RRID":{"HPA028076":"AB_2672476","HPA028096":null,"HPA028412":"AB_2672592","HPA028414":"AB_10601366"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.58e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.87e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.75e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"}},{"Gene":"EPB41L2","Gene synonym":["4.1-G","4.1G"],"Ensembl":"ENSG00000079819","Gene description":"Erythrocyte membrane protein band 4.1 like 2","Uniprot":["O43491"],"Chromosome":"6","Position":"130839347-131063322","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","Mitosis","Transport"],"Molecular function":["Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"368.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"349.9","Microglial cells":"422.3","Muller glia cells":"397.8","Rod photoreceptor cells":"1231.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Kidney - Fibroblasts","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005730","HPA006642"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"54000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cell Junctions"],"Antibody RRID":{"HPA005730":"AB_1848195","HPA006642":"AB_1848194"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.41e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.16e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"}},{"Gene":"EPB41L3","Gene synonym":["4.1B","DAL1","KIAA0987"],"Ensembl":"ENSG00000082397","Gene description":"Erythrocyte membrane protein band 4.1 like 3","Uniprot":["Q9Y2J2"],"Chromosome":"18","Position":"5392381-5630700","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Actin-binding"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"302.7","Inhibitory neurons":"232.4","Late spermatids":"306.6","Oligodendrocytes":"150.3","Syncytiotrophoblasts":"256.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"7.7","non-classical monocyte":"12.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"12.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Kidney - Proximal tubular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028605"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA028605":"AB_10611963"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-3"}},{"Gene":"EPCAM","Gene synonym":["17-1A","323\/A3","CD326","CO-17A","EGP-2","EGP34","EGP40","Ep-CAM","ESA","GA733-2","HEA125","KS1\/4","KSA","Ly74","M4S1","MH99","MIC18","MK-1","MOC31","TACST-1","TACSTD1","TROP1"],"Ensembl":"ENSG00000119888","Gene description":"Epithelial cell adhesion molecule","Uniprot":["P16422"],"Chromosome":"2","Position":"47345158-47387601","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Tumor antigen"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Hereditary nonpolyposis colorectal cancer"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"806.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"2396.3","Enteroendocrine cells":"962.1","Intestinal goblet cells":"1437.9","Paneth cells":"2254.7","Proximal enterocytes":"2636.9","Undifferentiated cells":"1431.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"691.3"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Liver - Cholangiocyte","Lung - Alveolar cells type 2","Skin - Eccrine sweat gland cells","Stomach - Gastric mucous cells","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003809","HPA026761","CAB030012","CAB055098","HPA067463"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"22000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB003809":"AB_562285","CAB030012":"AB_756075","CAB055098":"AB_2335685","HPA026761":"AB_1848198","HPA067463":"AB_2685846"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.30e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"}},{"Gene":"EPG5","Gene synonym":["hEPG5","KIAA1632"],"Ensembl":"ENSG00000152223","Gene description":"Ectopic P-granules autophagy protein 5 homolog","Uniprot":["Q9HCE0"],"Chromosome":"18","Position":"45847609-45967329","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"52.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031689"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA031689":"AB_10609997"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.04e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"}},{"Gene":"EPGN","Gene synonym":["ALGV3072","EPG","PRO9904"],"Ensembl":"ENSG00000182585","Gene description":"Epithelial mitogen","Uniprot":["Q6UW88"],"Chromosome":"4","Position":"74308470-74316789","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"49.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"13.3","Basal squamous epithelial cells":"13.0","Squamous epithelial cells":"7.6","Suprabasal keratinocytes":"35.5","Thymic epithelial cells":"22.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"head and neck cancer":"7.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"13.9"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014420"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA014420":"AB_10601551"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.40e-4"}},{"Gene":"EPHA1","Gene synonym":["EPH","EPHT","EPHT1"],"Ensembl":"ENSG00000146904","Gene description":"EPH receptor A1","Uniprot":["P21709"],"Chromosome":"7","Position":"143390289-143408856","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Cell adhesion"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"57.2","parathyroid gland":"206.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"21.9","Squamous epithelial cells":"33.3","Suprabasal keratinocytes":"34.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"memory CD4 T-cell":"1.9","naive CD4 T-cell":"3.8","naive CD8 T-cell":"2.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"T-cells":"3.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Prostate - Prostate basal glandular cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026144"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"32000000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026144":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"}},{"Gene":"EPHA10","Gene synonym":["FLJ16103","FLJ33655"],"Ensembl":"ENSG00000183317","Gene description":"EPH receptor A10","Uniprot":["Q5JZY3"],"Chromosome":"1","Position":"37713880-37765133","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"7.6","intestine":"13.4","testis":"13.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"50.9","Late spermatids":"181.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027497"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027497":"AB_10601158"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"}},{"Gene":"EPHA2","Gene synonym":["ECK"],"Ensembl":"ENSG00000142627","Gene description":"EPH receptor A2","Uniprot":["P29317"],"Chromosome":"1","Position":"16124337-16156069","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Angiogenesis","Apoptosis","Cell adhesion","Differentiation","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Cataract","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"147.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"162.5","Glandular and luminal cells":"169.4","Ionocytes":"161.9","Squamous epithelial cells":"161.5","Suprabasal keratinocytes":"195.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"94","RNA blood cell specific nTPM":{"plasmacytoid DC":"9.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"94","RNA blood lineage specific nTPM":{"dendritic cells":"9.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010464"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Golgi apparatus","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nuclear speckles","Golgi apparatus"],"Antibody RRID":{"CAB010464":"AB_631436"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"}},{"Gene":"EPHA3","Gene synonym":["ETK","ETK1","HEK","HEK4","TYRO4"],"Ensembl":"ENSG00000044524","Gene description":"EPH receptor A3","Uniprot":["P29320"],"Chromosome":"3","Position":"89107621-89482134","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"31.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"69.6","Inhibitory neurons":"103.5","Microglial cells":"100.3","Oligodendrocytes":"45.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"12.1"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Heart muscle - Fibroblasts","Liver - Hepatic stellate cells","Lung - Fibroblast_2","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Testis - Peritubular cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010462","HPA069390"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Plasma membrane","Actin filaments","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Nuclear membrane","Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm","Actin filaments"],"Antibody RRID":{"CAB010462":"AB_2099218","HPA069390":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.28e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"}},{"Gene":"EPHA4","Gene synonym":["Hek8","TYRO1"],"Ensembl":"ENSG00000116106","Gene description":"EPH receptor A4","Uniprot":["P54764"],"Chromosome":"2","Position":"221418027-221574202","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"39.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"313.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"14.9"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"23.8","hippocampal formation":"20.9"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"1.6","gdT-cell":"1.7","MAIT T-cell":"1.7","memory B-cell":"1.3","memory CD4 T-cell":"2.5","memory CD8 T-cell":"1.7","naive B-cell":"1.2","naive CD4 T-cell":"1.0","NK-cell":"3.5","T-reg":"1.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB028368"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9300000","Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB028368":"AB_2099353"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.56e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.67e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"}},{"Gene":"EPHA5","Gene synonym":["CEK7","EHK1","Hek7","TYRO4"],"Ensembl":"ENSG00000145242","Gene description":"EPH receptor A5","Uniprot":["P54756"],"Chromosome":"4","Position":"65319563-65670495","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Neurogenesis"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"21.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"199.1","Inhibitory neurons":"158.7","Oligodendrocyte precursor cells":"91.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.8","prostate cancer":"0.5"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"21.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"21.7"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"33000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"}},{"Gene":"EPHA6","Gene synonym":["FLJ35246"],"Ensembl":"ENSG00000080224","Gene description":"EPH receptor A6","Uniprot":["Q9UF33"],"Chromosome":"3","Position":"96814581-97752460","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"24.2","ovary":"6.3","testis":"8.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Astrocytes":"408.4","Early spermatids":"404.1","Excitatory neurons":"418.9","Inhibitory neurons":"861.6","Late spermatids":"232.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"0.7"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"24.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"11.0","Rhabdoid":"7.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007397","HPA058047"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA007397":"AB_2667821","HPA058047":"AB_2683588"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-3"}},{"Gene":"EPHA7","Gene synonym":["Hek11"],"Ensembl":"ENSG00000135333","Gene description":"EPH receptor A7","Uniprot":["Q15375"],"Chromosome":"6","Position":"93240020-93419687","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"24.6","parathyroid gland":"69.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"136.5","Inhibitory neurons":"167.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"6.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"32.5","Sarcoma":"27.4"},"RNA tissue cell type enrichment":["Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010496"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"660000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010496":"AB_2099673"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"}},{"Gene":"EPHA8","Gene synonym":["EEK","Hek3"],"Ensembl":"ENSG00000070886","Gene description":"EPH receptor A8","Uniprot":["P29322"],"Chromosome":"1","Position":"22563489-22603595","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"choroid plexus":"27.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"2.6","Early spermatids":"2.4","Horizontal cells":"5.1","Late spermatids":"4.5","Pancreatic endocrine cells":"1.7","Rod photoreceptor cells":"10.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"3.9","Uterine cancer":"4.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"13.0"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"cerebellum":"11.7"},"Antibody":["CAB009660","HPA031433"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009660":"AB_2099696","HPA031433":"AB_10601371"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"}},{"Gene":"EPHB1","Gene synonym":["EPHT2","Hek6"],"Ensembl":"ENSG00000154928","Gene description":"EPH receptor B1","Uniprot":["P54762"],"Chromosome":"3","Position":"134597801-135260467","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Neurogenesis"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"40.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"192.6","dendritic cells":"111.8","Early spermatids":"41.8","Excitatory neurons":"47.3","Inhibitory neurons":"43.3","Late spermatids":"41.7","Oligodendrocyte precursor cells":"74.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"7.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"33","RNA blood cell specific nTPM":{"neutrophil":"24.0","plasmacytoid DC":"23.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"dendritic cells":"23.3","granulocytes":"24.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"11.2"},"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Kidney - Fibroblasts","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067740"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Endoplasmic reticulum","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA067740":"AB_2685895"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-4"}},{"Gene":"EPHB2","Gene synonym":["DRT","EPHT3","ERK","Hek5","Tyro5"],"Ensembl":"ENSG00000133216","Gene description":"EPH receptor B2","Uniprot":["P29323"],"Chromosome":"1","Position":"22710839-22921500","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"23.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"46.1","Enteroendocrine cells":"54.7","Intestinal goblet cells":"45.1","Oligodendrocytes":"72.0","Undifferentiated cells":"98.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"23.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Outer root sheath cells","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013647","HPA071200"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"380000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB013647":null,"HPA071200":"AB_2686360"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.98e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"}},{"Gene":"EPHB3","Gene synonym":["ETK2","Hek2","Tyro6"],"Ensembl":"ENSG00000182580","Gene description":"EPH receptor B3","Uniprot":["P54753"],"Chromosome":"3","Position":"184561785-184582408","Protein class":["Cancer-related genes","Enzymes","Predicted membrane proteins"],"Biological process":["Angiogenesis","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"51.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"39.7","Breast glandular cells":"44.7","Breast myoepithelial cells":"51.0","Enteroendocrine cells":"42.4","Squamous epithelial cells":"44.1","Suprabasal keratinocytes":"55.6","Undifferentiated cells":"58.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007698","HPA008184","CAB034350"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034350":"AB_2262377","HPA007698":"AB_1848205","HPA008184":"AB_1848206"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.88e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"}},{"Gene":"EPHB4","Gene synonym":["HTK","Tyro11"],"Ensembl":"ENSG00000196411","Gene description":"EPH receptor B4","Uniprot":["P54760"],"Chromosome":"7","Position":"100802565-100827523","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"48.1","Cytotrophoblasts":"64.9","Endothelial cells":"61.6","Syncytiotrophoblasts":"201.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"2.0","neutrophil":"4.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013537"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013537":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.56e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.33e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.84e-4"}},{"Gene":"EPHB6","Gene synonym":["HEP"],"Ensembl":"ENSG00000106123","Gene description":"EPH receptor B6","Uniprot":[],"Chromosome":"7","Position":"142855061-142871094","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"66.0","skin 1":"65.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Muller glia cells":"196.5","Prostatic glandular cells":"78.2","Suprabasal keratinocytes":"106.2","Thymic epithelial cells":"184.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035784"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear speckles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035784":"AB_2674781"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.80e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.10e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.68e-5"}},{"Gene":"EPHX1","Gene synonym":["EPHX"],"Ensembl":"ENSG00000143819","Gene description":"Epoxide hydrolase 1","Uniprot":["P07099"],"Chromosome":"1","Position":"225810124-225845563","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Aromatic hydrocarbons catabolism","Detoxification","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"1178.6","liver":"1705.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"658.2","Ionocytes":"356.7","Theca cells":"706.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"liver cancer":"1047.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"2.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020593","HPA048847"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA020593":"AB_10601373","HPA048847":"AB_2680538"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.02e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"}},{"Gene":"EPHX3","Gene synonym":["ABHD9","FLJ22408"],"Ensembl":"ENSG00000105131","Gene description":"Epoxide hydrolase 3","Uniprot":["Q9H6B9"],"Chromosome":"19","Position":"15226919-15233435","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"68.9","skin 1":"76.5","vagina":"36.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"15.0","Club cells":"18.6","Ionocytes":"14.6","Serous glandular cells":"13.5","Squamous epithelial cells":"37.6","Suprabasal keratinocytes":"68.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"30.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"1.9","non-classical monocyte":"2.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"1.3","monocytes":"2.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bile duct cancer":"5.5","lung cancer":"2.5","pancreatic cancer":"2.1","testis cancer":"3.4"},"RNA tissue cell type enrichment":["Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012842"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA012842":"AB_10601648"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.27e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"}},{"Gene":"EPHX4","Gene synonym":["ABHD7","EH4","EPHXRP","FLJ90341"],"Ensembl":"ENSG00000172031","Gene description":"Epoxide hydrolase 4","Uniprot":["Q8IUS5"],"Chromosome":"1","Position":"92029985-92063538","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.9","choroid plexus":"5.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"54.6","Horizontal cells":"11.5","Inhibitory neurons":"31.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"12.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"T-cells":"12.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035067"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035067":"AB_10601465"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.43e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.00e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"EPOR","Gene synonym":[],"Ensembl":"ENSG00000187266","Gene description":"Erythropoietin receptor","Uniprot":["P19235"],"Chromosome":"19","Position":"11377207-11384342","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Congenital erythrocytosis","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"85.7","granulocytes":"33.1","Hofbauer cells":"37.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"20.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077654"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA077654":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.17e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"}},{"Gene":"EPS8","Gene synonym":[],"Ensembl":"ENSG00000151491","Gene description":"Epidermal growth factor receptor pathway substrate 8","Uniprot":["Q12929"],"Chromosome":"12","Position":"15620134-15882329","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Smooth muscle cells":"267.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"22.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003897","HPA050209"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA003897":"AB_1848224","HPA050209":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.33e-7"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.45e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.11e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"}},{"Gene":"EPSTI1","Gene synonym":["BRESI1","MGC29634"],"Ensembl":"ENSG00000133106","Gene description":"Epithelial stromal interaction 1","Uniprot":["Q96J88"],"Chromosome":"13","Position":"42886388-42992271","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"118.0","Extravillous trophoblasts":"190.1","Hofbauer cells":"89.6","Proximal enterocytes":"107.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017362"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017362":"AB_1848226"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.66e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"}},{"Gene":"EQTN","Gene synonym":["AFAF","C9orf11","equatorin","SPACA8"],"Ensembl":"ENSG00000120160","Gene description":"Equatorin","Uniprot":["Q9NQ60"],"Chromosome":"9","Position":"27284654-27297150","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"testis":"37.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Early spermatids":"914.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015089","HPA015504"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Plasma membrane","Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA015089":"AB_1845795","HPA015504":"AB_2067598"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"}},{"Gene":"ERAL1","Gene synonym":["HERA-B"],"Ensembl":"ENSG00000132591","Gene description":"Era like 12S mitochondrial rRNA chaperone 1","Uniprot":["O75616"],"Chromosome":"17","Position":"28855010-28861061","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Ribosome biogenesis"],"Molecular function":["RNA-binding","rRNA-binding"],"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"71.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021425","HPA024423"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA021425":"AB_1848228","HPA024423":"AB_1848229"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"}},{"Gene":"ERBB2","Gene synonym":["CD340","HER-2","HER2","NEU","NGL"],"Ensembl":"ENSG00000141736","Gene description":"Erb-b2 receptor tyrosine kinase 2","Uniprot":["P04626"],"Chromosome":"17","Position":"39687914-39730426","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"122.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"5.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"5.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"breast cancer":"837.2","Esophageal cancer":"442.3","Gastric cancer":"212.0"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000043","HPA001060","HPA001338","HPA001383","CAB020416","CAB062555"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"980000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB000043":"AB_2335701","CAB020416":"AB_442047","CAB062555":"AB_2665610","HPA001060":"AB_2666185","HPA001338":"AB_2666279","HPA001383":"AB_1078500"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.99e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.17e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.41e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"}},{"Gene":"ERBB3","Gene synonym":["HER3","LCCS2"],"Ensembl":"ENSG00000065361","Gene description":"Erb-b2 receptor tyrosine kinase 3","Uniprot":["P21860"],"Chromosome":"12","Position":"56076799-56103505","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"210.8","Schwann cells":"220.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"2.4","neutrophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Breast - Breast glandular cells","Lung - Alveolar cells type 2","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025331","HPA045396","HPA070524"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB025331":null,"HPA045396":"AB_2679312","HPA070524":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"}},{"Gene":"ERBB4","Gene synonym":["ALS19","HER4"],"Ensembl":"ENSG00000178568","Gene description":"Erb-b2 receptor tyrosine kinase 4","Uniprot":["Q15303"],"Chromosome":"2","Position":"211375717-212538841","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Lactation","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Amyotrophic lateral sclerosis","Cancer-related genes","Disease variant","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"16.9","fallopian tube":"11.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1957.3","Inhibitory neurons":"5974.5","Oligodendrocyte precursor cells":"2268.6","Oligodendrocytes":"991.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"breast cancer":"4.1","endometrial cancer":"2.1","glioma":"1.2","ovarian cancer":"2.8","testis cancer":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"3.9"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Skin - Eccrine sweat gland cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000276","HPA012016","CAB025522"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000276":null,"CAB025522":null,"HPA012016":"AB_1846541"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"}},{"Gene":"ERCC3","Gene synonym":["BTF2","RAD25","XPB"],"Ensembl":"ENSG00000163161","Gene description":"ERCC excision repair 3, TFIIH core complex helicase subunit","Uniprot":["P19447"],"Chromosome":"2","Position":"127257290-127294166","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Cockayne syndrome","Deafness","Disease variant","Dwarfism","Ichthyosis","Xeroderma pigmentosum"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037153","HPA046077"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB037153":"AB_796181","HPA046077":"AB_2679527"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.30e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"}},{"Gene":"ERCC6L2","Gene synonym":["C9orf102","FLJ37706","HEBO","RAD26L"],"Ensembl":"ENSG00000182150","Gene description":"ERCC excision repair 6 like 2","Uniprot":["Q5T890"],"Chromosome":"9","Position":"95871264-96121154","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"102.5","Oligodendrocyte precursor cells":"125.2","Oligodendrocytes":"111.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021259","HPA021260","HPA021271","HPA022422"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA021259":"AB_1859542","HPA021260":"AB_1859544","HPA021271":"AB_1859543","HPA022422":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.70e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"}},{"Gene":"EREG","Gene synonym":["ER"],"Ensembl":"ENSG00000124882","Gene description":"Epiregulin","Uniprot":["O14944"],"Chromosome":"4","Position":"74365145-74388749","Protein class":["Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Angiogenesis","Differentiation"],"Molecular function":["Developmental protein","Growth factor","Mitogen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"bone marrow":"129.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"272.8","Langerhans cells":"226.9","Macrophages":"470.9","monocytes":"1638.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"11.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"122.8"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054373"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":46000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA054373":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.67e-7"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.45e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.57e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-3"}},{"Gene":"ERG28","Gene synonym":["C14orf1","NET51"],"Ensembl":"ENSG00000133935","Gene description":"Ergosterol biosynthesis 28 homolog","Uniprot":["Q9UKR5"],"Chromosome":"14","Position":"75649791-75660876","Protein class":["Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"258.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043172"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043172":"AB_10793942"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.30e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"}},{"Gene":"ERGIC1","Gene synonym":["ERGIC-32","ERGIC32","KIAA1181","NET24"],"Ensembl":"ENSG00000113719","Gene description":"Endoplasmic reticulum-golgi intermediate compartment 1","Uniprot":["Q969X5"],"Chromosome":"5","Position":"172834251-172952683","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018666","HPA018900"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA018666":"AB_1848241","HPA018900":"AB_1848242"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"}},{"Gene":"ERGIC2","Gene synonym":["Erv41","PTX1"],"Ensembl":"ENSG00000087502","Gene description":"ERGIC and golgi 2","Uniprot":["Q96RQ1"],"Chromosome":"12","Position":"29337352-29381189","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"436.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049695"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli rim","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Nucleoli rim"],"Antibody RRID":{"HPA049695":"AB_2680855"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.06e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.18e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.02e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.76e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"}},{"Gene":"ERGIC3","Gene synonym":["C20orf47","CGI-54","Erv46","NY-BR-84","PRO0989","SDBCAG84"],"Ensembl":"ENSG00000125991","Gene description":"ERGIC and golgi 3","Uniprot":["Q9Y282"],"Chromosome":"20","Position":"35542038-35557634","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"849.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015242","HPA015968"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015242":"AB_1848238","HPA015968":"AB_1848239"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.20e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.81e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"}},{"Gene":"ERI3","Gene synonym":["FLJ22943","PINT1","PRNPIP"],"Ensembl":"ENSG00000117419","Gene description":"ERI1 exoribonuclease family member 3","Uniprot":["O43414"],"Chromosome":"1","Position":"44221070-44355260","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Exonuclease","Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"965.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027147","HPA029895"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027147":"AB_1855725","HPA029895":"AB_2673239"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.18e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.04e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"}},{"Gene":"ERMAP","Gene synonym":["BTN5","RD","SC"],"Ensembl":"ENSG00000164010","Gene description":"Erythroblast membrane associated protein (Scianna blood group)","Uniprot":["Q96PL5"],"Chromosome":"1","Position":"42817122-42844991","Protein class":["Blood group antigen proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Blood group antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"66.6","Late spermatids":"38.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042573","HPA054672"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA042573":"AB_10794282","HPA054672":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"}},{"Gene":"ERMARD","Gene synonym":["C6orf70","dJ266L20.3","FLJ11152"],"Ensembl":"ENSG00000130023","Gene description":"ER membrane associated RNA degradation","Uniprot":["Q5T6L9"],"Chromosome":"6","Position":"169751622-169781600","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"50.8","Late spermatids":"48.7","Spermatocytes":"35.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041741"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041741":"AB_10804116"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"}},{"Gene":"ERMP1","Gene synonym":["FLJ23309","FXNA","KIAA1815"],"Ensembl":"ENSG00000099219","Gene description":"Endoplasmic reticulum metallopeptidase 1","Uniprot":["Q7Z2K6"],"Chromosome":"9","Position":"5765076-5833117","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"50.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"57.1","Granulosa cells":"55.3","Oligodendrocytes":"83.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Mitotic cells (Skin)","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055582"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055582":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.83e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"ERN1","Gene synonym":["IRE1","IRE1P"],"Ensembl":"ENSG00000178607","Gene description":"Endoplasmic reticulum to nucleus signaling 1","Uniprot":["O75460"],"Chromosome":"17","Position":"64039080-64130819","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Transcription","Transcription regulation","Unfolded protein response"],"Molecular function":["Hydrolase","Kinase","Multifunctional enzyme","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"53.0","pancreas":"66.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"249.1","Plasma cells":"325.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"17.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"7.7","granulocytes":"17.9","T-cells":"9.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Myeloma":"97.0"},"RNA tissue cell type enrichment":["Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009495","HPA027730"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009495":"AB_2098712","HPA027730":"AB_10602494"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.68e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"}},{"Gene":"ERN2","Gene synonym":["IRE1b"],"Ensembl":"ENSG00000134398","Gene description":"Endoplasmic reticulum to nucleus signaling 2","Uniprot":["Q76MJ5"],"Chromosome":"16","Position":"23690310-23713226","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Transcription","Transcription regulation"],"Molecular function":["Hydrolase","Kinase","Multifunctional enzyme","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"cervix":"19.5","gallbladder":"17.0","intestine":"28.9","salivary gland":"22.9","stomach 1":"51.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"57.3","Distal enterocytes":"86.3","Enteroendocrine cells":"40.1","Gastric mucus-secreting cells":"161.0","Intestinal goblet cells":"144.3","Ionocytes":"60.6","Undifferentiated cells":"48.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"17.0","pancreatic cancer":"19.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bile duct cancer":"13.0","colorectal cancer":"19.2","Gallbladder cancer":"8.7","Gastric cancer":"16.9","pancreatic cancer":"10.3"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Colon - Colon enterocytes","Lung - Respiratory ciliated cells","Pancreas - Ductal cells","Prostate - Urothelial cells","Skin - Eccrine sweat gland cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076875"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA076875":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-3"}},{"Gene":"ERVFRD-1","Gene synonym":["envFRD","ERVFRDE1","HERV-FRD","HERV-W\/FRD","syncytin-2"],"Ensembl":"ENSG00000244476","Gene description":"Endogenous retrovirus group FRD member 1, envelope","Uniprot":["P60508"],"Chromosome":"6","Position":"11102489-11111725","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"placenta":"37.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"50","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"676.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"60","RNA cell line specific nTPM":{"testis cancer":"38.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Adipose visceral - Mast cells","Colon - Mast cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011812"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Plasma membrane","Actin filaments"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA011812":"AB_1857702"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"}},{"Gene":"ERVH48-1","Gene synonym":["C21orf105","NDUFV3-AS1","SUPYN"],"Ensembl":"ENSG00000233056","Gene description":"Endogenous retrovirus group 48 member 1","Uniprot":["M5A8F1"],"Chromosome":"21","Position":"42916803-42925646","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"65","RNA tissue specific nTPM":{"placenta":"152.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Cytotrophoblasts":"133.3","Extravillous trophoblasts":"281.7","Syncytiotrophoblasts":"78.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"testis cancer":"74.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"7.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"granulocytes":"7.7"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"testis cancer":"44.6"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in female reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"57000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"}},{"Gene":"ERVMER34-1","Gene synonym":["envMER34"],"Ensembl":"ENSG00000226887","Gene description":"Endogenous retrovirus group MER34 member 1, envelope","Uniprot":["Q9H9K5"],"Chromosome":"4","Position":"52722618-52751586","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"12.9","placenta":"10.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cytotrophoblasts":"81.3","Extravillous trophoblasts":"96.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011423","HPA024053"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA011423":"AB_2668510","HPA024053":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.55e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"}},{"Gene":"ERVV-1","Gene synonym":["ENVV1","FLJ32214","HERV-V1"],"Ensembl":"ENSG00000269526","Gene description":"Endogenous retrovirus group V member 1, envelope","Uniprot":["B6SEH8"],"Chromosome":"19","Position":"53013921-53016122","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"placenta":"16.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"49","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"401.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"0.6","urothelial cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"testis cancer":"6.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076115"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA076115":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"}},{"Gene":"ERVV-2","Gene synonym":["ENVV2"],"Ensembl":"ENSG00000268964","Gene description":"Endogenous retrovirus group V member 2, envelope","Uniprot":["B6SEH9"],"Chromosome":"19","Position":"53044740-53051680","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"placenta":"8.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"91.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"20","RNA cell line specific nTPM":{"testis cancer":"10.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076115"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA076115":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-4"}},{"Gene":"ERVW-1","Gene synonym":["envW","ERVWE1","HERV-7q","HERV-W","HERV-W-ENV","HERVW"],"Ensembl":"ENSG00000242950","Gene description":"Endogenous retrovirus group W member 1, envelope","Uniprot":["Q9UQF0"],"Chromosome":"7","Position":"92468380-92477986","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"placenta":"54.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cytotrophoblasts":"278.1","Syncytiotrophoblasts":"1090.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"143","RNA cancer specific FPKM":{"testis cancer":"31.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Sarcoma":"25.3","testis cancer":"26.2"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"54000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"}},{"Gene":"ESAM","Gene synonym":["W117m"],"Ensembl":"ENSG00000149564","Gene description":"Endothelial cell adhesion molecule","Uniprot":["Q96AP7"],"Chromosome":"11","Position":"124752583-124762290","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"385.2","Endothelial cells":"271.5","Sertoli cells":"63.6","Smooth muscle cells":"101.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"8.2","naive B-cell":"7.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"7.5","granulocytes":"8.2","T-cells":"2.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"15.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Lung - Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056293","HPA072563"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"82000000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA056293":"AB_2683089","HPA072563":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"}},{"Gene":"ESPL1","Gene synonym":["ESP1","KIAA0165","SEPA"],"Ensembl":"ENSG00000135476","Gene description":"Extra spindle pole bodies like 1, separase","Uniprot":["Q14674"],"Chromosome":"12","Position":"53268299-53293638","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Chromosome partition"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"8.5","esophagus":"15.4","lymphoid tissue":"10.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"19.0","Squamous epithelial cells":"8.2","Suprabasal keratinocytes":"11.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Mitotic cells (Colon)","Heart muscle - Mitotic cells (Heart)","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Lung - Mitotic cells (Lung)","Stomach - Mitotic cells (Stomach)","Testis - Early spermatids","Thyroid - Mitotic cells (Thyroid)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012185","HPA073188"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB012185":"AB_304056","HPA073188":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.32e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.01e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.14e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.10e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"}},{"Gene":"ESPNL","Gene synonym":["FLJ42568"],"Ensembl":"ENSG00000144488","Gene description":"Espin like","Uniprot":["Q6ZVH7"],"Chromosome":"2","Position":"238100340-238133287","Protein class":["Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":["Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.0","intestine":"3.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"2.1","Granulosa cells":"1.7","Hepatocytes":"1.3","Muller glia cells":"1.6","Theca cells":"2.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"12","RNA brain regional specific nTPM":{"cerebellum":"5.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"2.8"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055103"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055103":"AB_2682694"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"}},{"Gene":"ESR1","Gene synonym":["ER-alpha","Era","ESR","NR3A1"],"Ensembl":"ENSG00000091831","Gene description":"Estrogen receptor 1","Uniprot":["P03372"],"Chromosome":"6","Position":"151656691-152129619","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Nuclear receptors","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"83.8","endometrium 1":"110.9","fallopian tube":"64.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"74.3","Early spermatids":"32.4","Endometrial ciliated cells":"75.5","Endometrial stromal cells":"73.6","Glandular and luminal cells":"96.6","Granulosa cells":"36.8","Hepatocytes":"48.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"40.2","endometrial cancer":"24.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"breast cancer":"15.8","cervical cancer":"5.0","Myeloma":"5.3"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000037","HPA000449","HPA000450","CAB055099","CAB072858"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB000037":"AB_563706","CAB055099":"AB_2101946","CAB072858":"AB_2665701","HPA000449":"AB_1078753","HPA000450":"AB_1078754"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.47e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"}},{"Gene":"ESYT1","Gene synonym":["FAM62A","KIAA0747","MBC2"],"Ensembl":"ENSG00000139641","Gene description":"Extended synaptotagmin 1","Uniprot":["Q9BSJ8"],"Chromosome":"12","Position":"56118250-56144674","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Colon - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016858","HPA076926"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"720000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA016858":"AB_1848404","HPA076926":"AB_2686819"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.86e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"}},{"Gene":"ESYT2","Gene synonym":["CHR2SYT","FAM62B","KIAA1228"],"Ensembl":"ENSG00000117868","Gene description":"Extended synaptotagmin 2","Uniprot":["A0FGR8"],"Chromosome":"7","Position":"158730995-158830253","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Endocytosis","Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"180.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002132","HPA070823"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002132":"AB_1078807","HPA070823":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.81e-5"}},{"Gene":"ESYT3","Gene synonym":["CHR3SYT","FAM62C"],"Ensembl":"ENSG00000158220","Gene description":"Extended synaptotagmin 3","Uniprot":["A0FGR9"],"Chromosome":"3","Position":"138434586-138481686","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.1","skin 1":"7.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"26.2","Alveolar cells type 2":"29.8","Cone photoreceptor cells":"8.6","Excitatory neurons":"9.3","Inhibitory neurons":"9.5","Rod photoreceptor cells":"7.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"2.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 2","Skin - Keratinocyte (granular)","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"7.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039200"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039200":"AB_10805356"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.30e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"}},{"Gene":"ETFA","Gene synonym":["EMA","GA2","MADD"],"Ensembl":"ENSG00000140374","Gene description":"Electron transfer flavoprotein subunit alpha","Uniprot":["P13804"],"Chromosome":"15","Position":"76215353-76311472","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Electron transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Glutaricaciduria"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"389.7","tongue":"493.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"405.3","Hepatocytes":"383.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Kidney - Proximal tubular cells","Liver - Hepatocytes","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018990","HPA018993","HPA018996","HPA024089"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"680000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA018990":"AB_1848277","HPA018993":"AB_1848275","HPA018996":"AB_1848276","HPA024089":"AB_1848278"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.04e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"}},{"Gene":"ETFDH","Gene synonym":["ETFQO"],"Ensembl":"ENSG00000171503","Gene description":"Electron transfer flavoprotein dehydrogenase","Uniprot":["Q16134"],"Chromosome":"4","Position":"158672125-158709623","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","FDA approved drug targets","Glutaricaciduria"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"196.4","tongue":"186.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"180.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041978"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041978":"AB_10795605"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.76e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"}},{"Gene":"ETNK1","Gene synonym":["EKI","EKI1"],"Ensembl":"ENSG00000139163","Gene description":"Ethanolamine kinase 1","Uniprot":["Q9HBU6"],"Chromosome":"12","Position":"22625075-22690665","Protein class":["Cancer-related genes","Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"396.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010712","HPA029407"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA010712":"AB_2668349","HPA029407":"AB_2673026"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.85e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.75e-4"}},{"Gene":"ETNK2","Gene synonym":["EKI2","FLJ10761"],"Ensembl":"ENSG00000143845","Gene description":"Ethanolamine kinase 2","Uniprot":["Q9NVF9"],"Chromosome":"1","Position":"204131062-204152044","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"kidney":"108.1","liver":"235.5","testis":"125.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"1397.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"32.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"44.9"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"basal ganglia":"22.6"},"Antibody":["HPA057167"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057167":"AB_2683358"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.11e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"}},{"Gene":"ETV6","Gene synonym":["TEL"],"Ensembl":"ENSG00000139083","Gene description":"ETS variant transcription factor 6","Uniprot":["P41212"],"Chromosome":"12","Position":"11649674-11895377","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"144.5","Microglial cells":"210.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000264"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA000264":"AB_611466"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.38e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.66e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.54e-5"}},{"Gene":"EVA1A","Gene synonym":["FAM176A","FLJ13391","TMEM166"],"Ensembl":"ENSG00000115363","Gene description":"Eva-1 homolog A, regulator of programmed cell death","Uniprot":["Q9H8M9"],"Chromosome":"2","Position":"75469302-75569722","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"liver":"191.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"65.2","Alveolar cells type 2":"47.2","Cytotrophoblasts":"42.0","Hepatocytes":"66.3","Proximal tubular cells":"58.2","Syncytiotrophoblasts":"155.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"77.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008055"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA008055":"AB_1080308"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.67e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.80e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"}},{"Gene":"EVA1B","Gene synonym":["C1orf78","FAM176B","FLJ10647"],"Ensembl":"ENSG00000142694","Gene description":"Eva-1 homolog B","Uniprot":["Q9NVM1"],"Chromosome":"1","Position":"36322031-36324154","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"146.5","Extravillous trophoblasts":"297.6","Syncytiotrophoblasts":"167.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"4.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041928","HPA043537"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA041928":"AB_2677752","HPA043537":"AB_2678538"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.58e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.82e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.79e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"}},{"Gene":"EVA1C","Gene synonym":["B18","B19","C21orf63","C21orf64","FAM176C","PRED34"],"Ensembl":"ENSG00000166979","Gene description":"Eva-1 homolog C","Uniprot":["P58658"],"Chromosome":"21","Position":"32412006-32515397","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"160.5","Ionocytes":"123.8","Late spermatids":"243.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"1.1","gdT-cell":"3.1","MAIT T-cell":"3.8","memory CD4 T-cell":"3.2","memory CD8 T-cell":"3.2","naive CD8 T-cell":"1.6","NK-cell":"3.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"1.1","NK-cells":"3.2","T-cells":"3.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015720","HPA029944","CAB034174"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034174":"AB_1564317","HPA015720":"AB_1845705","HPA029944":"AB_10601092"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.06e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"}},{"Gene":"EVC","Gene synonym":["DWF-1"],"Ensembl":"ENSG00000072840","Gene description":"EvC ciliary complex subunit 1","Uniprot":["P57679"],"Chromosome":"4","Position":"5711201-5814305","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Dwarfism","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"25.6","Endometrial stromal cells":"6.3","Microglial cells":"10.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"16.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008703","HPA016046"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008703":"AB_1078765","HPA016046":"AB_1848299"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.60e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.47e-5"}},{"Gene":"EVC2","Gene synonym":["LBN"],"Ensembl":"ENSG00000173040","Gene description":"EvC ciliary complex subunit 2","Uniprot":["Q86UK5"],"Chromosome":"4","Position":"5542772-5709548","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Dwarfism","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"17.1","Leydig cells":"12.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040910","HPA048122"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Microtubules","Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Microtubules","Cytokinetic bridge"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA040910":"AB_2677195","HPA048122":"AB_2680272"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.58e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-5"}},{"Gene":"EVI2A","Gene synonym":["EVDA","EVI2"],"Ensembl":"ENSG00000126860","Gene description":"Ecotropic viral integration site 2A","Uniprot":["P22794"],"Chromosome":"17","Position":"31316410-31321749","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"155.7","lymphoid tissue":"105.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"187.4","Kupffer cells":"232.9","Langerhans cells":"134.3","Macrophages":"126.9","monocytes":"110.1","NK-cells":"98.3","Oligodendrocytes":"206.6","T-cells":"107.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"29.3","Myeloma":"64.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045033","HPA057051"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA045033":"AB_2679191","HPA057051":"AB_2683321"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.55e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.63e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"}},{"Gene":"EXD2","Gene synonym":["C14orf114","EXDL2","FLJ10738"],"Ensembl":"ENSG00000081177","Gene description":"Exonuclease 3'-5' domain containing 2","Uniprot":["Q9NVH0"],"Chromosome":"14","Position":"69191511-69244020","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Exonuclease","Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002906","HPA005848"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"HPA002906":"AB_1078767","HPA005848":"AB_1078768"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.08e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"}},{"Gene":"EXOC1L","Gene synonym":[],"Ensembl":"ENSG00000250821","Gene description":"Exocyst complex component 1 like","Uniprot":["A0A1B0GW35"],"Chromosome":"4","Position":"55819790-55837489","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Distal tubular cells":"3.1","Early spermatids":"5.7","Late spermatids":"6.6","Theca cells":"2.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"20","RNA blood cell specific nTPM":{"NK-cell":"1.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"NK-cells":"1.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"pons and medulla":"2.8"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"EXOSC5","Gene synonym":["hRrp46p","MGC12901","p12B","RRP41B","RRP46","Rrp46p"],"Ensembl":"ENSG00000077348","Gene description":"Exosome component 5","Uniprot":["Q9NQT4"],"Chromosome":"19","Position":"41386374-41397359","Protein class":["Predicted intracellular proteins"],"Biological process":["rRNA processing"],"Molecular function":["RNA-binding"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"134.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053150","HPA055677"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA053150":"AB_2682058","HPA055677":"AB_2682882"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.45e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"}},{"Gene":"EXT1","Gene synonym":["LGCR","LGS","ttv"],"Ensembl":"ENSG00000182197","Gene description":"Exostosin glycosyltransferase 1","Uniprot":["Q16394"],"Chromosome":"8","Position":"117794490-118111826","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary multiple exostoses","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"123.4","Excitatory neurons":"226.2","Inhibitory neurons":"411.0","Microglial cells":"140.5","Oligodendrocyte precursor cells":"156.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044394"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044394":"AB_10963838"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.04e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"}},{"Gene":"EXT2","Gene synonym":["SOTV"],"Ensembl":"ENSG00000151348","Gene description":"Exostosin glycosyltransferase 2","Uniprot":["Q93063"],"Chromosome":"11","Position":"44095673-44251962","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Hereditary multiple exostoses","Intellectual disability","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078409"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"39000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA078409":"AB_2686884"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.50e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.36e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"}},{"Gene":"EXTL2","Gene synonym":[],"Ensembl":"ENSG00000162694","Gene description":"Exostosin like glycosyltransferase 2","Uniprot":["Q9UBQ6"],"Chromosome":"1","Position":"100872372-100895179","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"218.7","Theca cells":"231.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020716","HPA068921"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"80000000","Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB020716":null,"HPA068921":"AB_2686058"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.64e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"}},{"Gene":"EXTL3","Gene synonym":["botv","REGR"],"Ensembl":"ENSG00000012232","Gene description":"Exostosin like glycosyltransferase 3","Uniprot":["O43909"],"Chromosome":"8","Position":"28600469-28755599","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Dwarfism","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"40.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"5.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025387"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025387":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.47e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"}},{"Gene":"EYS","Gene synonym":["bA166P24.2","bA307F22.3","bA74E24.1","C6orf178","C6orf179","C6orf180","dJ1018A4.2","dJ303F19.1","EGFL10","EGFL11","RP25","SPAM"],"Ensembl":"ENSG00000188107","Gene description":"Eyes shut homolog","Uniprot":["Q5T1H1"],"Chromosome":"6","Position":"63719980-65707226","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"36","RNA tissue specific nTPM":{"retina":"24.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"156.8","Early spermatids":"96.3","Inhibitory neurons":"81.7","Late spermatids":"45.1","Rod photoreceptor cells":"162.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"2.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"}},{"Gene":"F11R","Gene synonym":["CD321","JAM-1","JAM-A","JAM1","JAMA","JCAM","PAM-1"],"Ensembl":"ENSG00000158769","Gene description":"F11 receptor","Uniprot":["Q9Y624"],"Chromosome":"1","Position":"160995211-161021343","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"201.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"165.5","neutrophil":"113.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"165.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"232.8"},"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Skeletal muscle - Endothelial cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004671","HPA043616","HPA061700"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1900000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Microtubules"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"CAB004671":"AB_425964","HPA043616":null,"HPA061700":"AB_2684589"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"}},{"Gene":"F2R","Gene synonym":["CF2R","PAR-1","PAR1","TR"],"Ensembl":"ENSG00000181104","Gene description":"Coagulation factor II thrombin receptor","Uniprot":["P25116"],"Chromosome":"5","Position":"76716126-76735770","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"69.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"47.1","Endothelial cells":"58.8","Fibroblasts":"64.0","Mucus glandular cells":"42.1","NK-cells":"91.6","Smooth muscle cells":"45.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"25.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"NK-cells":"7.0","T-cells":"25.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008973","CAB012962"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB008973":null,"CAB012962":"AB_2533198"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.21e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-3"}},{"Gene":"F2RL1","Gene synonym":["GPR11","PAR2"],"Ensembl":"ENSG00000164251","Gene description":"F2R like trypsin receptor 1","Uniprot":["P55085"],"Chromosome":"5","Position":"76818933-76835315","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"59.4","stomach 1":"44.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"75.1","Distal enterocytes":"74.0","Gastric mucus-secreting cells":"75.1","Glandular and luminal cells":"67.7","Intestinal goblet cells":"54.2","Proximal enterocytes":"57.0","Suprabasal keratinocytes":"98.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"42.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"42.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"178.2"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Heart muscle - Fibroblasts","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012989","HPA014091"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB012989":"AB_2533199","HPA014091":"AB_2668939"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.88e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.88e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.92e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.86e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"}},{"Gene":"F2RL2","Gene synonym":["PAR3"],"Ensembl":"ENSG00000164220","Gene description":"Coagulation factor II thrombin receptor like 2","Uniprot":["O00254"],"Chromosome":"5","Position":"76615482-76623413","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.9","gallbladder":"6.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"2.3","Fibroblasts":"4.3","Rod photoreceptor cells":"4.7","Schwann cells":"7.5","Smooth muscle cells":"2.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"9.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"10.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"10.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"35.3"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.69e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"}},{"Gene":"F2RL3","Gene synonym":["PAR4"],"Ensembl":"ENSG00000127533","Gene description":"F2R like thrombin or trypsin receptor 3","Uniprot":["Q96RI0"],"Chromosome":"19","Position":"16888999-16892606","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"19.0","lung":"33.4","thyroid gland":"19.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Adipocytes":"106.9","Endothelial cells":"28.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"10.1"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031401","HPA042340"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA031401":null,"HPA042340":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"}},{"Gene":"F3","Gene synonym":["CD142","TF"],"Ensembl":"ENSG00000117525","Gene description":"Coagulation factor III, tissue factor","Uniprot":["P13726"],"Chromosome":"1","Position":"94529173-94541759","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"680.9","Basal respiratory cells":"349.4","Club cells":"393.3","Exocrine glandular cells":"480.8","Ionocytes":"314.5","Peritubular cells":"515.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"689.5"},"RNA tissue cell type enrichment":["Kidney - Podocytes","Liver - Cholangiocyte","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009438","HPA049292","HPA069132"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":603000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB009438":"AB_668005","HPA049292":"AB_2680701","HPA069132":"AB_2686092"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.07e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"}},{"Gene":"FA2H","Gene synonym":["FAAH","FAXDC1","FLJ25287","SPG35"],"Ensembl":"ENSG00000103089","Gene description":"Fatty acid 2-hydroxylase","Uniprot":["Q7L5A8"],"Chromosome":"16","Position":"74712955-74774831","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Leukodystrophy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"183.9","stomach 1":"61.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"84.7","Oligodendrocyte precursor cells":"58.7","Oligodendrocytes":"290.7","Paneth cells":"66.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Cholangiocyte","Lung - Alveolar cells type 2","Skin - Sebaceous gland cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056614","HPA077840"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA056614":"AB_2683191","HPA077840":"AB_2686858"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.74e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.01e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"}},{"Gene":"FAAH","Gene synonym":["FAAH-1"],"Ensembl":"ENSG00000117480","Gene description":"Fatty acid amide hydrolase","Uniprot":["O00519"],"Chromosome":"1","Position":"46394317-46413848","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"121.1","Proximal enterocytes":"85.1","Spermatocytes":"79.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"68.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"29.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"26.4"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Breast glandular cells","Breast - Breast glandular cells","Prostate - Prostate glandular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007425"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007425":"AB_1078820"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.51e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.25e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.63e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-3"}},{"Gene":"FAAP100","Gene synonym":["C17orf70","FLJ22175"],"Ensembl":"ENSG00000185504","Gene description":"FA core complex associated protein 100","Uniprot":["Q0VG06"],"Chromosome":"17","Position":"81539885-81553961","Protein class":["Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023954","HPA024626","HPA026532"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA023954":"AB_1845601","HPA024626":"AB_1845602","HPA026532":"AB_1845603"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.00e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-1"}},{"Gene":"FADS1","Gene synonym":["D5D","FADS6","FADSD5","LLCDL1","TU12"],"Ensembl":"ENSG00000149485","Gene description":"Fatty acid desaturase 1","Uniprot":["O60427"],"Chromosome":"11","Position":"61799627-61829318","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"204.4","dendritic cells":"199.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells","Testis - Leydig cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042705"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042705":"AB_10795709"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.95e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.79e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.33e-4"}},{"Gene":"FADS2","Gene synonym":["D6D","DES6","FADSD6","LLCDL2","SLL0262","TU13"],"Ensembl":"ENSG00000134824","Gene description":"Fatty acid desaturase 2","Uniprot":["O95864"],"Chromosome":"11","Position":"61792980-61867354","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"364.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Basal prostatic cells":"449.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006741","HPA079284"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA006741":"AB_1078796","HPA079284":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.00e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.42e-4"}},{"Gene":"FADS3","Gene synonym":["CYB5RP","LLCDL3"],"Ensembl":"ENSG00000221968","Gene description":"Fatty acid desaturase 3","Uniprot":["Q9Y5Q0"],"Chromosome":"11","Position":"61873519-61892051","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"144.2","Alveolar cells type 1":"212.0","Extravillous trophoblasts":"151.6","Rod photoreceptor cells":"125.6","Schwann cells":"113.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"7.7","naive B-cell":"8.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"8.7","granulocytes":"5.7","T-cells":"2.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045224"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA045224":"AB_10967570"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.54e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.50e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"}},{"Gene":"FADS6","Gene synonym":[],"Ensembl":"ENSG00000172782","Gene description":"Fatty acid desaturase 6","Uniprot":[],"Chromosome":"17","Position":"74877302-74893781","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.7","epididymis":"18.2","intestine":"14.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Proximal enterocytes":"63.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016802"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016802":"AB_2669448"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"FAF2","Gene synonym":["ETEA","KIAA0887","UBXD8","UBXN3B"],"Ensembl":"ENSG00000113194","Gene description":"Fas associated factor family member 2","Uniprot":["Q96CS3"],"Chromosome":"5","Position":"176447628-176510074","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Unfolded protein response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065968","HPA071246","HPA073828"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum","Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Lipid droplets"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA065968":"AB_2685589","HPA071246":"AB_2732176","HPA073828":"AB_2686636"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.79e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.38e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"}},{"Gene":"FAIM2","Gene synonym":["KIAA0950","LFG","LFG2","LIFEGUARD","NMP35","TMBIM2"],"Ensembl":"ENSG00000135472","Gene description":"Fas apoptotic inhibitory molecule 2","Uniprot":["Q9BWQ8"],"Chromosome":"12","Position":"49866896-49904217","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"359.4","parathyroid gland":"98.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"118.5","Early spermatids":"246.7","Excitatory neurons":"76.5","Horizontal cells":"160.2","Inhibitory neurons":"102.5","Oligodendrocytes":"52.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"21.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"2.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"T-cells":"2.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"33.6"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Fibroblasts","Lung - Fibroblast_2","Stomach - Fibroblasts","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018790","HPA048800"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA018790":"AB_1852822","HPA048800":"AB_2680526"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-4"}},{"Gene":"FAM120A","Gene synonym":["C9orf10","KIAA0183","OSSA"],"Ensembl":"ENSG00000048828","Gene description":"Family with sequence similarity 120A","Uniprot":["Q9NZB2"],"Chromosome":"9","Position":"93451685-93566112","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["RNA-binding"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019734","HPA055800"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019734":"AB_1848369","HPA055800":"AB_2682925"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.03e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"}},{"Gene":"FAM120AOS","Gene synonym":["C9orf10OS"],"Ensembl":"ENSG00000188938","Gene description":"Family with sequence similarity 120A opposite strand","Uniprot":["Q5T036"],"Chromosome":"9","Position":"93431441-93453581","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"206.2","Syncytiotrophoblasts":"337.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021475"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021475":"AB_2670718"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.95e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.04e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"}},{"Gene":"FAM120B","Gene synonym":["CCPG","KIAA1838","PGCC1","SAN1"],"Ensembl":"ENSG00000112584","Gene description":"Family with sequence similarity 120B","Uniprot":["Q96EK7"],"Chromosome":"6","Position":"170290703-170407067","Protein class":["Predicted intracellular proteins"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Late spermatids":"1845.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037518","HPA037519"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA037518":"AB_10671626","HPA037519":"AB_10696935"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.70e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"FAM120C","Gene synonym":["CXorf17","FLJ20506","ORF34"],"Ensembl":"ENSG00000184083","Gene description":"Family with sequence similarity 120C","Uniprot":["Q9NX05"],"Chromosome":"X","Position":"54068324-54183281","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"31.8","Oligodendrocytes":"31.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047677","HPA054250"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA047677":"AB_2680118","HPA054250":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.48e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"}},{"Gene":"FAM122C","Gene synonym":["RP3-473B4.1"],"Ensembl":"ENSG00000156500","Gene description":"Family with sequence similarity 122C","Uniprot":["Q6P4D5"],"Chromosome":"X","Position":"134796395-134854835","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"12.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"74.9","Granulosa cells":"36.3","Theca cells":"26.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059961"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA059961":"AB_2684181"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-3"}},{"Gene":"FAM124A","Gene synonym":["FLJ30707"],"Ensembl":"ENSG00000150510","Gene description":"Family with sequence similarity 124 member A","Uniprot":["Q86V42"],"Chromosome":"13","Position":"51222334-51284239","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"59.1","choroid plexus":"26.7","retina":"25.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Oligodendrocytes":"219.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"6.2"},"RNA tissue cell type enrichment":["Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048182"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA048182":"AB_2680301"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"}},{"Gene":"FAM135A","Gene synonym":["FLJ20176","KIAA1411"],"Ensembl":"ENSG00000082269","Gene description":"Family with sequence similarity 135 member A","Uniprot":["Q9P2D6"],"Chromosome":"6","Position":"70412941-70561174","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"29.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"167.7","Inhibitory neurons":"168.9","Microglial cells":"128.6","Oligodendrocyte precursor cells":"209.9","Oligodendrocytes":"114.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Prostate - Prostate glandular cells","Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031743","HPA031744"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA031743":"AB_10600767","HPA031744":"AB_10601101"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.00e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.46e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"}},{"Gene":"FAM151A","Gene synonym":["C1orf179","MGC27169"],"Ensembl":"ENSG00000162391","Gene description":"Family with sequence similarity 151 member A","Uniprot":["Q8WW52"],"Chromosome":"1","Position":"54609181-54623556","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"66.3","kidney":"174.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"630.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"2.3","renal cancer":"3.2","testis cancer":"5.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"2.7","liver cancer":"2.9"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016840"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016840":"AB_2669461"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.09e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"}},{"Gene":"FAM155A","Gene synonym":[],"Ensembl":"ENSG00000204442","Gene description":"Family with sequence similarity 155 member A","Uniprot":["B1AL88"],"Chromosome":"13","Position":"107163510-107867496","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.7","pituitary gland":"5.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"890.1","Excitatory neurons":"3006.9","Inhibitory neurons":"2099.2","Oligodendrocyte precursor cells":"2209.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"6.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039453"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039453":"AB_10795290"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"}},{"Gene":"FAM155B","Gene synonym":["CXorf63","TED","TMEM28"],"Ensembl":"ENSG00000130054","Gene description":"Family with sequence similarity 155 member B","Uniprot":["O75949"],"Chromosome":"X","Position":"69504326-69532508","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"heart muscle":"43.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"18.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"8.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Prostate - Prostate glandular cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036093"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036093":"AB_10673613"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.61e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"}},{"Gene":"FAM160A2","Gene synonym":["C11orf56","DKFZP566M1046","FHIP","FLJ22665","KIAA1759"],"Ensembl":"ENSG00000051009","Gene description":"Family with sequence similarity 160 member A2","Uniprot":["Q8N612"],"Chromosome":"11","Position":"6211345-6234711","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055994","HPA063987"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA055994":"AB_2682999","HPA063987":"AB_2685166"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"}},{"Gene":"FAM162A","Gene synonym":["C3orf28","E2IG5"],"Ensembl":"ENSG00000114023","Gene description":"Family with sequence similarity 162 member A","Uniprot":["Q96A26"],"Chromosome":"3","Position":"122384176-122412334","Protein class":["Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"593.1","Distal enterocytes":"650.7","Suprabasal keratinocytes":"543.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Skin - Keratinocyte (other)","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035856","HPA075611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA035856":"AB_10611965","HPA075611":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-4"}},{"Gene":"FAM162B","Gene synonym":["bA86F4.2","C6orf189"],"Ensembl":"ENSG00000183807","Gene description":"Family with sequence similarity 162 member B","Uniprot":["Q5T6X4"],"Chromosome":"6","Position":"116752197-116765719","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"65.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"32.2","Early spermatids":"22.0","Endometrial stromal cells":"16.4","Salivary duct cells":"21.8","Sertoli cells":"27.6","Smooth muscle cells":"84.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"testis cancer":"32.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"7.2","testis cancer":"4.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells","Liver - Hepatic stellate cells","Prostate - Fibroblasts","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036112","HPA060342"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036112":"AB_10696649","HPA060342":"AB_2684258"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"}},{"Gene":"FAM163A","Gene synonym":["C1orf76","MGC16664","NDSP"],"Ensembl":"ENSG00000143340","Gene description":"Family with sequence similarity 163 member A","Uniprot":["Q96GL9"],"Chromosome":"1","Position":"179743163-179816198","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.0","lymphoid tissue":"15.2","pituitary gland":"29.6","testis":"12.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"33.9","Late spermatids":"50.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"Neuroblastoma":"51.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"}},{"Gene":"FAM163B","Gene synonym":["C9orf166"],"Ensembl":"ENSG00000196990","Gene description":"Family with sequence similarity 163 member B","Uniprot":["P0C2L3"],"Chromosome":"9","Position":"133577081-133609389","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"60.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"24.5","Inhibitory neurons":"17.4","Late spermatids":"27.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"3.2"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"amygdala":"26.5","basal ganglia":"44.4","cerebral cortex":"60.1","hippocampal formation":"38.2","white matter":"32.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Neuroblastoma":"14.9"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067336"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Nuclear bodies","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA067336":"AB_2685825"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-4"}},{"Gene":"FAM171A1","Gene synonym":["APCN","C10orf38","FLJ12884"],"Ensembl":"ENSG00000148468","Gene description":"Family with sequence similarity 171 member A1","Uniprot":["Q5VUB5"],"Chromosome":"10","Position":"15211643-15371289","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"86.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"255.6","Cholangiocytes":"90.5","Excitatory neurons":"164.5","Inhibitory neurons":"74.9","Oligodendrocytes":"202.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"1.7","MAIT T-cell":"4.4","memory CD4 T-cell":"2.5","memory CD8 T-cell":"2.2","naive CD4 T-cell":"4.7","naive CD8 T-cell":"2.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"T-cells":"4.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051345"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA051345":"AB_2681449"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.71e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.90e-6"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"}},{"Gene":"FAM171A2","Gene synonym":["MGC34829"],"Ensembl":"ENSG00000161682","Gene description":"Family with sequence similarity 171 member A2","Uniprot":["A8MVW0"],"Chromosome":"17","Position":"44353215-44363853","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.3","pituitary gland":"7.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"43.3","Horizontal cells":"31.4","Muller glia cells":"121.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"14.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"13.7"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019770"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019770":"AB_1848383"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"}},{"Gene":"FAM171B","Gene synonym":["FLJ34104","KIAA1946"],"Ensembl":"ENSG00000144369","Gene description":"Family with sequence similarity 171 member B","Uniprot":["Q6P995"],"Chromosome":"2","Position":"186694060-186765959","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"54.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"250.5","Bipolar cells":"131.1","Excitatory neurons":"124.5","Inhibitory neurons":"111.4","Oligodendrocyte precursor cells":"97.7","Oligodendrocytes":"74.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"15.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Sarcoma":"40.6"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010529","HPA010639","HPA013434"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA010529":null,"HPA010639":"AB_1852447","HPA013434":"AB_2262499"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.51e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.03e-4"}},{"Gene":"FAM174A","Gene synonym":["NS5ATP6","TMEM157","UNQ1912"],"Ensembl":"ENSG00000174132","Gene description":"Family with sequence similarity 174 member A","Uniprot":["Q8TBP5"],"Chromosome":"5","Position":"100535374-100586741","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"169.0","Respiratory ciliated cells":"155.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"55.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"55.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019539"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA019539":"AB_2293743"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.57e-6"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.48e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"}},{"Gene":"FAM174B","Gene synonym":["LOC400451","MGC102891"],"Ensembl":"ENSG00000185442","Gene description":"Family with sequence similarity 174 member B","Uniprot":["Q3ZCQ3"],"Chromosome":"15","Position":"92617448-92809884","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"76.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"76.4","Intestinal goblet cells":"58.5","Late spermatids":"61.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"8.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"3.5","granulocytes":"2.9","T-cells":"8.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"66.8"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015306"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA015306":"AB_2669182"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.03e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"}},{"Gene":"FAM174C","Gene synonym":["C19orf24","FLJ20640"],"Ensembl":"ENSG00000228300","Gene description":"Family with sequence similarity 174 member C","Uniprot":["Q9BVV8"],"Chromosome":"19","Position":"1275530-1279244","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"315.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043279","HPA047026"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA043279":"AB_10794656","HPA047026":"AB_2679906"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"}},{"Gene":"FAM187A","Gene synonym":[],"Ensembl":"ENSG00000214447","Gene description":"Family with sequence similarity 187 member A","Uniprot":["A6NFU0"],"Chromosome":"17","Position":"44899712-44905390","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"15.0","testis":"15.9"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043131"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043131":"AB_10796686"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"FAM187B","Gene synonym":["FLJ25660","TMEM162"],"Ensembl":"ENSG00000177558","Gene description":"Family with sequence similarity 187 member B","Uniprot":["Q17R55"],"Chromosome":"19","Position":"35224800-35228729","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"241","RNA tissue specific nTPM":{"testis":"68.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Late spermatids":"2714.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079535"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA079535":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"}},{"Gene":"FAM189A1","Gene synonym":["KIAA0574","TMEM228"],"Ensembl":"ENSG00000104059","Gene description":"Family with sequence similarity 189 member A1","Uniprot":["O60320"],"Chromosome":"15","Position":"29120254-29570723","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"5.3","thyroid gland":"3.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"199.9","Inhibitory neurons":"193.6","Oligodendrocyte precursor cells":"57.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"2.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009410","HPA010637"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA009410":"AB_1852332","HPA010637":"AB_1852333"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"}},{"Gene":"FAM189A2","Gene synonym":["C9orf61","X123"],"Ensembl":"ENSG00000135063","Gene description":"Family with sequence similarity 189 member A2","Uniprot":["Q15884"],"Chromosome":"9","Position":"69324567-69392558","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"48.3","thyroid gland":"58.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"248.3","Skeletal myocytes":"166.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"22.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029411","HPA057207"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029411":"AB_10602338","HPA057207":"AB_2683369"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.16e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"}},{"Gene":"FAM189B","Gene synonym":["C1orf2","cote1"],"Ensembl":"ENSG00000160767","Gene description":"Family with sequence similarity 189 member B","Uniprot":["P81408"],"Chromosome":"1","Position":"155247205-155255483","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006659","HPA050674"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA006659":"AB_1078339","HPA050674":"AB_2681213"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.98e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.59e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.43e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.43e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"}},{"Gene":"FAM205A","Gene synonym":["C9orf144B"],"Ensembl":"ENSG00000205108","Gene description":"Family with sequence similarity 205 member A","Uniprot":["Q6ZU69"],"Chromosome":"9","Position":"34723053-34729488","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"96","RNA tissue specific nTPM":{"testis":"24.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"151.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071267"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli fibrillar center","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA071267":"AB_2686376"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"FAM205C","Gene synonym":["FAM205CP"],"Ensembl":"ENSG00000187791","Gene description":"Family with sequence similarity 205 member C","Uniprot":["A6NFA0"],"Chromosome":"9","Position":"34889066-34895764","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"38","RNA tissue specific nTPM":{"testis":"28.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"40","RNA single cell type specific nTPM":{"Early spermatids":"192.2","Late spermatids":"502.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"FAM209A","Gene synonym":["C20orf106","dJ1153D9.3"],"Ensembl":"ENSG00000124103","Gene description":"Family with sequence similarity 209 member A","Uniprot":["Q5JX71"],"Chromosome":"20","Position":"56517187-56526152","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"104.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"170","RNA single cell type specific nTPM":{"Early spermatids":"1883.3","Late spermatids":"751.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"1.7"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079442"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA079442":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"}},{"Gene":"FAM209B","Gene synonym":["C20orf107","dJ1153D9.4"],"Ensembl":"ENSG00000213714","Gene description":"Family with sequence similarity 209 member B","Uniprot":["Q5JX69"],"Chromosome":"20","Position":"56533246-56536520","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"testis":"114.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"97","RNA single cell type specific nTPM":{"Early spermatids":"1511.9","Late spermatids":"527.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042144"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042144":"AB_10794414"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-4"}},{"Gene":"FAM214A","Gene synonym":["FLJ10980","KIAA1370"],"Ensembl":"ENSG00000047346","Gene description":"Family with sequence similarity 214 member A","Uniprot":["Q32MH5"],"Chromosome":"15","Position":"52581317-52709817","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039369","HPA040180"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA039369":"AB_10795250","HPA040180":"AB_10794736"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.27e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.68e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-3"}},{"Gene":"FAM234A","Gene synonym":["C16orf9","DKFZP761D0211","FLJ32603","ITFG3"],"Ensembl":"ENSG00000167930","Gene description":"Family with sequence similarity 234 member A","Uniprot":["Q9H0X4"],"Chromosome":"16","Position":"234521-272183","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"183.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011651","HPA071871"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5300000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA011651":null,"HPA071871":"AB_2732188"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"}},{"Gene":"FAM234B","Gene synonym":["KIAA1467"],"Ensembl":"ENSG00000084444","Gene description":"Family with sequence similarity 234 member B","Uniprot":["A2RU67"],"Chromosome":"12","Position":"13044381-13142521","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"22.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"19.5","Excitatory neurons":"20.4","Inhibitory neurons":"17.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"16.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Skin - Keratinocyte (other)","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010803","HPA010850"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA010803":"AB_1079200","HPA010850":"AB_2732402"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"}},{"Gene":"FAM237A","Gene synonym":[],"Ensembl":"ENSG00000235118","Gene description":"Family with sequence similarity 237 member A","Uniprot":["A0A1B0GTK4"],"Chromosome":"2","Position":"206642487-206649365","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"3.6","Late spermatids":"2.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"1.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"FAM241A","Gene synonym":["C4orf32","FLJ39370"],"Ensembl":"ENSG00000174749","Gene description":"Family with sequence similarity 241 member A","Uniprot":["Q8N8J7"],"Chromosome":"4","Position":"112145454-112195256","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"271.8","Endothelial cells":"98.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Kidney - Endothelial cells","Lung - Endothelial cells","Prostate - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062443","HPA069294"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA062443":"AB_2684765","HPA069294":"AB_2686111"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.87e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"}},{"Gene":"FAM241B","Gene synonym":["C10orf35"],"Ensembl":"ENSG00000171224","Gene description":"Family with sequence similarity 241 member B","Uniprot":["Q96D05"],"Chromosome":"10","Position":"69630247-69633596","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"40.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"38.2","Late spermatids":"66.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"gdT-cell":"4.3","MAIT T-cell":"10.9","memory CD4 T-cell":"10.5","memory CD8 T-cell":"7.0","naive CD4 T-cell":"17.2","naive CD8 T-cell":"5.7","T-reg":"7.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"25","RNA blood lineage specific nTPM":{"T-cells":"17.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034591"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Centrosome"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA034591":"AB_10670572"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.64e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.72e-4"}},{"Gene":"FAM24A","Gene synonym":["AC073585.4"],"Ensembl":"ENSG00000203795","Gene description":"Family with sequence similarity 24 member A","Uniprot":["A6NFZ4"],"Chromosome":"10","Position":"122910610-122913111","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"118","RNA tissue specific nTPM":{"testis":"17.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"44","RNA single cell type specific nTPM":{"Early spermatids":"420.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052490"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052490":"AB_2681851"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"FAM24B","Gene synonym":["AC073585.2","MGC45962"],"Ensembl":"ENSG00000213185","Gene description":"Family with sequence similarity 24 member B","Uniprot":["Q8N5W8"],"Chromosome":"10","Position":"122849078-122879641","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"15.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal tubular cells":"84.0","Early spermatids":"46.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Kidney - Intercalated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052490"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052490":"AB_2681851"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-3"}},{"Gene":"FAM3A","Gene synonym":["2-19","DXS560S","XAP-7"],"Ensembl":"ENSG00000071889","Gene description":"FAM3 metabolism regulating signaling molecule A","Uniprot":["P98173"],"Chromosome":"X","Position":"154506159-154516242","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"115.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025016","HPA035268","HPA056991"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli rim","Mitotic chromosome"],"Secretome location":"Secreted to blood","CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nucleoli rim"],"Subcellular additional location":["Nucleoplasm","Mitotic chromosome"],"Antibody RRID":{"CAB025016":null,"HPA035268":null,"HPA056991":"AB_2683303"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.76e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"}},{"Gene":"FAM3B","Gene synonym":["2-21","C21orf11","C21orf76","D21M16SJHU19e","ORF9","PANDER","PRED44"],"Ensembl":"ENSG00000183844","Gene description":"FAM3 metabolism regulating signaling molecule B","Uniprot":["P58499"],"Chromosome":"21","Position":"41304212-41357727","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"142.6","pancreas":"212.3","salivary gland":"119.4","stomach 1":"114.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"314.2","Exocrine glandular cells":"255.7","Proximal enterocytes":"858.9","Serous glandular cells":"237.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"40.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1.4","neutrophil":"2.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"7.9"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells (progenitors)","Liver - Cholangiocyte","Prostate - Prostate glandular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015885","HPA029777","CAB034131"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":2080000,"Blood concentration - Conc. blood MS [pg\/L]":"250000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB034131":"AB_2231472","HPA015885":"AB_1848396","HPA029777":"AB_2673194"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"}},{"Gene":"FAM3D","Gene synonym":["EF7","OIT1"],"Ensembl":"ENSG00000198643","Gene description":"FAM3 metabolism regulating signaling molecule D","Uniprot":["Q96BQ1"],"Chromosome":"3","Position":"58633946-58666834","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"264.8","intestine":"488.7","salivary gland":"468.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"362.6","Distal enterocytes":"895.2","Enteroendocrine cells":"314.4","Intestinal goblet cells":"1080.9","Ionocytes":"345.5","Paneth cells":"577.0","Proximal enterocytes":"354.1","Serous glandular cells":"524.0","Undifferentiated cells":"471.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"151.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"3.7"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"granulocytes":"3.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"colorectal cancer":"27.4","Gastric cancer":"12.9"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Pancreas - Ductal cells","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013844"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013844":"AB_2668897"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.51e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.89e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"}},{"Gene":"FAM76A","Gene synonym":["MGC34648"],"Ensembl":"ENSG00000009780","Gene description":"Family with sequence similarity 76 member A","Uniprot":["Q8TAV0"],"Chromosome":"1","Position":"27725961-27763116","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"94.6","Late spermatids":"134.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044762","HPA077897"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA044762":"AB_10795886","HPA077897":"AB_2686867"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.26e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"}},{"Gene":"FAM76B","Gene synonym":["MGC33371"],"Ensembl":"ENSG00000077458","Gene description":"Family with sequence similarity 76 member B","Uniprot":["Q5HYJ3"],"Chromosome":"11","Position":"95768953-95790409","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"39.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Early spermatids":"234.4","Late spermatids":"413.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036608"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA036608":"AB_2675215"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.72e-4"}},{"Gene":"FAM8A1","Gene synonym":["AHCP"],"Ensembl":"ENSG00000137414","Gene description":"Family with sequence similarity 8 member A1","Uniprot":["Q9UBU6"],"Chromosome":"6","Position":"17600302-17611715","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"622.1","Late spermatids":"364.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"5.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044698","HPA073675"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA044698":"AB_2679051","HPA073675":"AB_2732236"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"}},{"Gene":"FAM98B","Gene synonym":["FLJ38426"],"Ensembl":"ENSG00000171262","Gene description":"Family with sequence similarity 98 member B","Uniprot":["Q52LJ0"],"Chromosome":"15","Position":"38454127-38487710","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008320","HPA008502"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000","Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA008320":"AB_1848419","HPA008502":"AB_1848420"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"}},{"Gene":"FAM9C","Gene synonym":["TEX39C"],"Ensembl":"ENSG00000187268","Gene description":"Family with sequence similarity 9 member C","Uniprot":["Q8IZT9"],"Chromosome":"X","Position":"13035617-13044682","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"lymphoid tissue":"38.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Spermatocytes":"95.6","Spermatogonia":"26.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"22","RNA cancer specific FPKM":{"testis cancer":"4.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"137.5"},"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"FANCA","Gene synonym":["FA-H","FAA","FACA","FAH","FANCH"],"Ensembl":"ENSG00000187741","Gene description":"FA complementation group A","Uniprot":["O15360"],"Chromosome":"16","Position":"89737549-89816657","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"20.2","testis":"21.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"48.0","Spermatogonia":"30.4","Syncytiotrophoblasts":"25.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063236"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA063236":"AB_2684966"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"}},{"Gene":"FANCD2","Gene synonym":["FA-D2","FACD","FAD","FANCD"],"Ensembl":"ENSG00000144554","Gene description":"FA complementation group D2","Uniprot":["Q9BXW9"],"Chromosome":"3","Position":"10026414-10101932","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"17.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"24.0","Spermatocytes":"63.3","Spermatogonia":"25.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Mitotic cells (Lung)","Stomach - Mitotic cells (Stomach)","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016117","HPA063742"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Nuclear bodies","Cytosol"],"Antibody RRID":{"CAB016117":"AB_2278211","HPA063742":"AB_2685110"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.00e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"}},{"Gene":"FANCI","Gene synonym":["FLJ10719","KIAA1794"],"Ensembl":"ENSG00000140525","Gene description":"FA complementation group I","Uniprot":["Q9NVI1"],"Chromosome":"15","Position":"89243945-89317261","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"31.4","lymphoid tissue":"44.2","testis":"32.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"50.4","Spermatocytes":"80.7","Spermatogonia":"52.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"23.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039972","HPA040379"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA039972":"AB_10673265","HPA040379":"AB_2676951"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.71e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"}},{"Gene":"FANCM","Gene synonym":["FAAP250","KIAA1596"],"Ensembl":"ENSG00000187790","Gene description":"FA complementation group M","Uniprot":["Q8IYD8"],"Chromosome":"14","Position":"45135930-45200890","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Disease variant","Premature ovarian failure"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"209.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055144"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA055144":"AB_2682715"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"}},{"Gene":"FAR1","Gene synonym":["FLJ22728","MLSTD2","SDR10E1"],"Ensembl":"ENSG00000197601","Gene description":"Fatty acyl-CoA reductase 1","Uniprot":["Q8WVX9"],"Chromosome":"11","Position":"13668668-13732346","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cataract","Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"206.6","Oligodendrocytes":"412.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017322"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA017322":"AB_1848424"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.27e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"}},{"Gene":"FAR2","Gene synonym":["FLJ10462","MLSTD1","SDR10E2"],"Ensembl":"ENSG00000064763","Gene description":"Fatty acyl-CoA reductase 2","Uniprot":["Q96K12"],"Chromosome":"12","Position":"29149103-29340980","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"36.2","intestine":"34.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"112.5","Inhibitory neurons":"168.4","Microglial cells":"62.0","Syncytiotrophoblasts":"289.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"50.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Endothelial cells","Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015884"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA015884":"AB_1853998"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"}},{"Gene":"FARS2","Gene synonym":["dJ236A3.1","FARS1","mtPheRS"],"Ensembl":"ENSG00000145982","Gene description":"Phenylalanyl-tRNA synthetase 2, mitochondrial","Uniprot":["O95363"],"Chromosome":"6","Position":"5261044-5829192","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"106.9","Excitatory neurons":"213.9","Inhibitory neurons":"119.7","Microglial cells":"104.0","Oligodendrocyte precursor cells":"178.6","Oligodendrocytes":"115.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018148","HPA028836"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018148":"AB_1848426","HPA028836":"AB_10601377"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.14e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"}},{"Gene":"FARSA","Gene synonym":["CML33","FARSL","FARSLA"],"Ensembl":"ENSG00000179115","Gene description":"Phenylalanyl-tRNA synthetase subunit alpha","Uniprot":["Q9Y285"],"Chromosome":"19","Position":"12922479-12934037","Protein class":["Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001911"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001911":"AB_1848427"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.23e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.32e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"}},{"Gene":"FAS","Gene synonym":["APO-1","APT1","CD95","FAS1","TNFRSF6"],"Ensembl":"ENSG00000026103","Gene description":"Fas cell surface death receptor","Uniprot":["P25445"],"Chromosome":"10","Position":"88990531-89017059","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":["Calmodulin-binding","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"66.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"114.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"114.7","T-cells":"96.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027444"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":11900000,"Blood concentration - Conc. blood MS [pg\/L]":"420000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA027444":"AB_10601378"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"}},{"Gene":"FASLG","Gene synonym":["APT1LG1","CD178","FasL","TNFSF6"],"Ensembl":"ENSG00000117560","Gene description":"Fas ligand","Uniprot":["P48023"],"Chromosome":"1","Position":"172659103-172666876","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Apoptosis","Transcription","Transcription regulation"],"Molecular function":["Cytokine","Repressor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"5.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"NK-cells":"72.9","T-cells":"26.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"58.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"NK-cells":"41.5","T-cells":"58.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - NK-cells (Liver)","Lung - NK-cells (Lung)","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054959"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":73600,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054959":"AB_2682650"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"}},{"Gene":"FAT1","Gene synonym":["CDHF7","CDHR8","FAT"],"Ensembl":"ENSG00000083857","Gene description":"FAT atypical cadherin 1","Uniprot":["Q14517"],"Chromosome":"4","Position":"186587794-186726722","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"119.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"113.3","Salivary duct cells":"99.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001869","HPA023882"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4600000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001869":"AB_1078818","HPA023882":"AB_1848429"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.22e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"}},{"Gene":"FAT2","Gene synonym":["CDHF8","CDHR9","HFAT2","MEGF1"],"Ensembl":"ENSG00000086570","Gene description":"FAT atypical cadherin 2","Uniprot":["Q9NYQ8"],"Chromosome":"5","Position":"151504093-151568944","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"113.4","esophagus":"50.9","skin 1":"56.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"35.4","Basal respiratory cells":"31.1","Basal squamous epithelial cells":"34.5","Extravillous trophoblasts":"23.3","Serous glandular cells":"22.1","Squamous epithelial cells":"54.8","Suprabasal keratinocytes":"42.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"cervical cancer":"13.9","head and neck cancer":"21.4","lung cancer":"6.1","urothelial cancer":"5.6"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"cerebellum":"113.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"39.5","head and neck cancer":"57.9"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"18","RNA mouse brain regional specific nTPM":{"cerebellum":"32.0"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"56","RNA pig brain regional specific nTPM":{"cerebellum":"224.4"},"Antibody":["CAB033680","HPA044656"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"300000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB033680":"AB_2100956","HPA044656":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"}},{"Gene":"FAT3","Gene synonym":["CDHF15","CDHR10","KIAA1989"],"Ensembl":"ENSG00000165323","Gene description":"FAT atypical cadherin 3","Uniprot":["Q8TDW7"],"Chromosome":"11","Position":"92224818-92896473","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"19.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"257.5","Excitatory neurons":"506.5","Inhibitory neurons":"145.0","Oligodendrocyte precursor cells":"84.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"1.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Heart muscle - Smooth muscle cells","Kidney - Fibroblasts","Liver - Hepatic stellate cells","Prostate - Smooth muscle cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026878","HPA074824"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4700","Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA026878":"AB_1848430","HPA074824":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"}},{"Gene":"FAT4","Gene synonym":["CDHF14","CDHR11","FAT-J"],"Ensembl":"ENSG00000196159","Gene description":"FAT atypical cadherin 4","Uniprot":["Q6V0I7"],"Chromosome":"4","Position":"125314918-125492932","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"23.5","Endothelial cells":"30.5","Fibroblasts":"25.2","Inhibitory neurons":"33.9","Microglial cells":"22.8","Oligodendrocytes":"51.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"19.0"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052819"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2300000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA052819":"AB_2681963"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.89e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"}},{"Gene":"FATE1","Gene synonym":["CT43","FATE"],"Ensembl":"ENSG00000147378","Gene description":"Fetal and adult testis expressed 1","Uniprot":["Q969F0"],"Chromosome":"X","Position":"151716035-151723194","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"102","RNA tissue specific nTPM":{"testis":"239.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"38.7","Late spermatids":"57.9","Sertoli cells":"204.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"testis cancer":"6.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034604"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034604":"AB_10602318"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.88e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"}},{"Gene":"FAXC","Gene synonym":["C6orf168","dJ273F20","MGC2817"],"Ensembl":"ENSG00000146267","Gene description":"Failed axon connections homolog, metaxin like GST domain containing","Uniprot":["Q5TGI0"],"Chromosome":"6","Position":"99271168-99350062","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"22.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"24.1","Excitatory neurons":"56.2","Horizontal cells":"22.4","Inhibitory neurons":"58.7","Oligodendrocyte precursor cells":"41.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Mesothelial cells","Prostate - Smooth muscle cells","Skin - Eccrine sweat gland cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039106"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA039106":"AB_10697546"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"}},{"Gene":"FAXDC2","Gene synonym":["C5orf4","FLJ13758"],"Ensembl":"ENSG00000170271","Gene description":"Fatty acid hydroxylase domain containing 2","Uniprot":["Q96IV6"],"Chromosome":"5","Position":"154818492-154859252","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"304.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"56.9","Intestinal goblet cells":"61.6","Oligodendrocytes":"155.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.87e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.71e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"}},{"Gene":"FBH1","Gene synonym":["Fbx18","FBXO18","FLJ14590"],"Ensembl":"ENSG00000134452","Gene description":"F-box DNA helicase 1","Uniprot":["Q8NFZ0"],"Chromosome":"10","Position":"5890203-5937594","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002844"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 34: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002844":"AB_1078829"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.73e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"}},{"Gene":"FBXO31","Gene synonym":["FBX14","Fbx31","FBXO14","MGC15419"],"Ensembl":"ENSG00000103264","Gene description":"F-box protein 31","Uniprot":["Q5XUX0"],"Chromosome":"16","Position":"87326987-87392142","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","DNA damage","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"65.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"63.6","Cone photoreceptor cells":"50.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030150"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA030150":"AB_10670559"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.16e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"}},{"Gene":"FBXO33","Gene synonym":["Fbx33"],"Ensembl":"ENSG00000165355","Gene description":"F-box protein 33","Uniprot":["Q7Z6M2"],"Chromosome":"14","Position":"39397669-39432500","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"52.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"81.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046657"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA046657":"AB_10960398"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.94e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.58e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"}},{"Gene":"FBXO41","Gene synonym":["Fbx41","KIAA1940"],"Ensembl":"ENSG00000163013","Gene description":"F-box protein 41","Uniprot":["Q8TF61"],"Chromosome":"2","Position":"73254682-73284478","Protein class":["Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"42.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"12.5","Excitatory neurons":"28.4","Horizontal cells":"30.8","Inhibitory neurons":"21.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"21.2","basal ganglia":"31.0","cerebral cortex":"42.3","hippocampal formation":"29.6","white matter":"24.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055246","HPA058386"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA055246":"AB_2682758","HPA058386":"AB_2683701"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.76e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"}},{"Gene":"FBXO9","Gene synonym":["FBX9","NY-REN-57"],"Ensembl":"ENSG00000112146","Gene description":"F-box protein 9","Uniprot":["Q9UK97"],"Chromosome":"6","Position":"53051991-53100873","Protein class":["Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064246"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA064246":"AB_2685225"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.51e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.82e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-3"}},{"Gene":"FBXW12","Gene synonym":["Fbw12","FBXO35"],"Ensembl":"ENSG00000164049","Gene description":"F-box and WD repeat domain containing 12","Uniprot":["Q6X9E4"],"Chromosome":"3","Position":"48372219-48401259","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"pancreas":"6.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"5.4","Excitatory neurons":"2.3","Inhibitory neurons":"1.9","Late spermatids":"10.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037491","HPA037492"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA037491":"AB_2675504","HPA037492":"AB_2675505"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-3"}},{"Gene":"FBXW7","Gene synonym":["AGO","CDC4","FBW7","FBX30","FBXW6","FLJ11071","SEL-10","SEL10"],"Ensembl":"ENSG00000109670","Gene description":"F-box and WD repeat domain containing 7","Uniprot":["Q969H0"],"Chromosome":"4","Position":"152320544-152536092","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Biological rhythms","DNA damage","DNA repair","Host-virus interaction","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"66.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"522.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"23.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013793","CAB029987"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB013793":"AB_2533451","CAB029987":"AB_2246842"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"}},{"Gene":"FCAMR","Gene synonym":["CD351","FCA\/MR","FKSG87"],"Ensembl":"ENSG00000162897","Gene description":"Fc fragment of IgA and IgM receptor","Uniprot":["Q8WWV6"],"Chromosome":"1","Position":"206957965-206970625","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"kidney":"38.1","lymphoid tissue":"26.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Distal tubular cells":"6.2","Proximal tubular cells":"24.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"2.4","renal cancer":"5.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056505"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5300000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056505":"AB_2732604"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"}},{"Gene":"FCAR","Gene synonym":["CD89"],"Ensembl":"ENSG00000186431","Gene description":"Fc fragment of IgA receptor","Uniprot":["P24071"],"Chromosome":"19","Position":"54874235-54891420","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["IgA-binding protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"26.1","lung":"10.5","lymphoid tissue":"13.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Kupffer cells":"25.6","Macrophages":"17.5","monocytes":"25.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"classical monocyte":"1.2","neutrophil":"4.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"27","RNA blood lineage specific nTPM":{"granulocytes":"4.0","monocytes":"1.2"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Colon - Neutrophils","Heart muscle - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2","Skeletal muscle - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014050"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014050":"AB_1846338"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"}},{"Gene":"FCER1A","Gene synonym":["FCE1A"],"Ensembl":"ENSG00000179639","Gene description":"Fc fragment of IgE receptor Ia","Uniprot":["P12319"],"Chromosome":"1","Position":"159289714-159308224","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["IgE-binding protein","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"33.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Langerhans cells":"2617.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"21557.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"21557.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"114","RNA cell line specific nTPM":{"Leukemia":"39.0","lymphoma":"14.0"},"RNA tissue cell type enrichment":["Skin - Langerhans cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022102","HPA036051","CAB055526"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022102":null,"CAB055526":null,"HPA036051":"AB_2674919"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"}},{"Gene":"FCER1G","Gene synonym":[],"Ensembl":"ENSG00000158869","Gene description":"Fc fragment of IgE receptor Ig","Uniprot":["P30273"],"Chromosome":"1","Position":"161215234-161220699","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["IgE-binding protein","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"441.6","lymphoid tissue":"470.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"936.3","granulocytes":"1019.7","Hofbauer cells":"2872.0","Kupffer cells":"1487.5","Langerhans cells":"1904.8","Macrophages":"1775.7","monocytes":"2846.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"basophil":"1987.3","classical monocyte":"3240.2","intermediate monocyte":"5333.6","myeloid DC":"2386.3","neutrophil":"1831.0","NK-cell":"1750.9","non-classical monocyte":"6984.5","plasmacytoid DC":"3315.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"54.2","lymphoma":"18.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022108","HPA026872"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022108":null,"HPA026872":"AB_1848473"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"}},{"Gene":"FCER2","Gene synonym":["CD23","CD23A","CLEC4J","FCE2"],"Ensembl":"ENSG00000104921","Gene description":"Fc fragment of IgE receptor II","Uniprot":["P06734"],"Chromosome":"19","Position":"7688758-7702146","Protein class":["Cancer-related genes","CD markers","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["IgE-binding protein","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"42.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"B-cells":"143.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"2.1"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"1.3"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"24","RNA blood cell specific nTPM":{"memory B-cell":"200.9","naive B-cell":"496.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"34","RNA blood lineage specific nTPM":{"B-cells":"496.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"225","RNA cell line specific nTPM":{"Leukemia":"40.0","lymphoma":"36.4","Myeloma":"39.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002624","HPA008928","HPA067430"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002624":null,"HPA008928":"AB_1846285","HPA067430":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"}},{"Gene":"FCGR1A","Gene synonym":["CD64","CD64A"],"Ensembl":"ENSG00000150337","Gene description":"Fc fragment of IgG receptor Ia","Uniprot":["P12314"],"Chromosome":"1","Position":"149782671-149791675","Protein class":["CD markers","FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["IgG-binding protein","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"93.3","lymphoid tissue":"41.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hofbauer cells":"239.6","Kupffer cells":"107.6","Late spermatids":"61.2","Macrophages":"76.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"10.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"classical monocyte":"131.5","intermediate monocyte":"54.7","myeloid DC":"35.6","neutrophil":"93.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"53","RNA blood lineage specific nTPM":{"dendritic cells":"35.6","granulocytes":"93.4","monocytes":"131.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"46","RNA cell line specific nTPM":{"Leukemia":"22.9"},"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Lung - Macrophages","Prostate - Macrophages","Stomach - Macrophages","Testis - Late spermatids","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026910"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus","Plasma membrane"],"Antibody RRID":{"HPA026910":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.83e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"}},{"Gene":"FCGR1B","Gene synonym":["CD64b"],"Ensembl":"ENSG00000198019","Gene description":"Fc fragment of IgG receptor Ib","Uniprot":["Q92637"],"Chromosome":"1","Position":"121087345-121097161","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["IgG-binding protein","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"51.5","lymphoid tissue":"18.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"73.8","Kupffer cells":"33.9","Macrophages":"24.9","Microglial cells":"10.9","monocytes":"12.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"31.2","neutrophil":"36.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"36.3","monocytes":"31.2"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"Leukemia":"7.3"},"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Kidney - Macrophages","Prostate - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026910"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus","Plasma membrane"],"Antibody RRID":{"HPA026910":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"}},{"Gene":"FCGR2A","Gene synonym":["CD32","CD32A","CDw32","FCG2","FCGR2","FCGR2A1","IGFR2"],"Ensembl":"ENSG00000143226","Gene description":"Fc fragment of IgG receptor IIa","Uniprot":["P12318"],"Chromosome":"1","Position":"161505430-161524013","Protein class":["CD markers","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":["IgG-binding protein","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"101.7","placenta":"107.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hofbauer cells":"203.5","Kupffer cells":"184.5","Langerhans cells":"426.8","Macrophages":"271.2","monocytes":"139.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"2322.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2322.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"31.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Neutrophils","Lung - Neutrophil_2","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010718","HPA010776","HPA014730"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"46000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA010718":"AB_1078463","HPA010776":null,"HPA014730":"AB_2669074"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.49e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"}},{"Gene":"FCGR2B","Gene synonym":["CD32","CD32B","FCG2","FCGR2"],"Ensembl":"ENSG00000072694","Gene description":"Fc fragment of IgG receptor IIb","Uniprot":["P31994"],"Chromosome":"1","Position":"161663147-161678654","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["IgG-binding protein","Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets","Proto-oncogene","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"placenta":"398.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"63.9","Endothelial cells":"87.8","Fibroblasts":"54.4","Langerhans cells":"336.1","Macrophages":"128.4","Plasma cells":"65.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"327.2","memory B-cell":"202.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"14.3","lymphoma":"24.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Liver - Sinusoid Endothelial cells","Skeletal muscle - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB007796","HPA014730"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB007796":"AB_562288","HPA014730":"AB_2669074"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.82e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"}},{"Gene":"FCGR3A","Gene synonym":["CD16","CD16a","FCG3","FCGR3"],"Ensembl":"ENSG00000203747","Gene description":"Fc fragment of IgG receptor IIIa","Uniprot":["P08637"],"Chromosome":"1","Position":"161541759-161550737","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity"],"Molecular function":["IgG-binding protein","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"206.3","lymphoid tissue":"306.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hofbauer cells":"243.9","Kupffer cells":"232.2","Macrophages":"324.9","monocytes":"901.8","NK-cells":"607.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"1763.5","neutrophil":"1169.8","non-classical monocyte":"3948.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1169.8","monocytes":"3948.7"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032435","HPA055431"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB032435":"AB_626925","HPA055431":"AB_2682815"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.22e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"}},{"Gene":"FCGR3B","Gene synonym":["CD16","CD16b","FCG3","FCGR3"],"Ensembl":"ENSG00000162747","Gene description":"Fc fragment of IgG receptor IIIb","Uniprot":["O75015"],"Chromosome":"1","Position":"161623196-161631963","Protein class":["CD markers","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["IgG-binding protein","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"36.6","lymphoid tissue":"82.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Serous glandular cells":"22.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"6.7"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"79","RNA blood cell specific nTPM":{"neutrophil":"7208.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"79","RNA blood lineage specific nTPM":{"granulocytes":"7208.7"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Colon - Neutrophils","Heart muscle - Neutrophils","Skeletal muscle - Neutrophils","Stomach - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"}},{"Gene":"FCGRT","Gene synonym":["alpha-chain","FCRN"],"Ensembl":"ENSG00000104870","Gene description":"Fc fragment of IgG receptor and transporter","Uniprot":["P55899"],"Chromosome":"19","Position":"49506816-49526428","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["IgG-binding protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"1408.0","Paneth cells":"786.7","Proximal enterocytes":"1849.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2346.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"dendritic cells":"922.9","granulocytes":"2346.7","monocytes":"1364.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"284.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Liver - Hepatocytes","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012122","HPA015130"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012122":"AB_1848474","HPA015130":"AB_1848475"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-3"}},{"Gene":"FCMR","Gene synonym":["FAIM3","TOSO"],"Ensembl":"ENSG00000162894","Gene description":"Fc fragment of IgM receptor","Uniprot":["O60667"],"Chromosome":"1","Position":"206903317-206923247","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"65.5","lymphoid tissue":"180.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"B-cells":"338.5","NK-cells":"97.6","T-cells":"108.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Leukemia":"20.3","lymphoma":"51.8","Myeloma":"40.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003910"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Focal adhesion sites"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5500000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Plasma membrane","Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA003910":"AB_1078798"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.23e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-3"}},{"Gene":"FCN1","Gene synonym":["FCNM"],"Ensembl":"ENSG00000085265","Gene description":"Ficolin 1","Uniprot":["O00602"],"Chromosome":"9","Position":"134903232-134917912","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"158.9","lung":"46.2","lymphoid tissue":"96.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hofbauer cells":"767.1","Kupffer cells":"937.2","Macrophages":"509.8","monocytes":"1153.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1699.8","intermediate monocyte":"1195.1"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"monocytes":"1699.8"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"1.2"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Lung - Neutrophil_2"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000685","HPA001295","CAB016760"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1060000000,"Blood concentration - Conc. blood MS [pg\/L]":"36000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016760":null,"HPA000685":"AB_1078840","HPA001295":"AB_1078842"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.98e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"}},{"Gene":"FCRL1","Gene synonym":["CD307a","FCRH1","IFGP1","IRTA5"],"Ensembl":"ENSG00000163534","Gene description":"Fc receptor like 1","Uniprot":["Q96LA6"],"Chromosome":"1","Position":"157794403-157820120","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"bone marrow":"8.0","intestine":"8.6","lymphoid tissue":"27.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"37","RNA single cell type specific nTPM":{"B-cells":"100.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"49","RNA blood cell specific nTPM":{"memory B-cell":"39.3","naive B-cell":"68.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"62","RNA blood lineage specific nTPM":{"B-cells":"68.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"38","RNA cell line specific nTPM":{"lymphoma":"11.2"},"RNA tissue cell type enrichment":["Heart muscle - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013323"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"290000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013323":"AB_1848480"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"}},{"Gene":"FCRL2","Gene synonym":["CD307b","FCRH2","IRTA4","SPAP1"],"Ensembl":"ENSG00000132704","Gene description":"Fc receptor like 2","Uniprot":["Q96LA5"],"Chromosome":"1","Position":"157745733-157777132","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"intestine":"20.9","lymphoid tissue":"34.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"B-cells":"74.6","Plasma cells":"45.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"34","RNA blood cell specific nTPM":{"memory B-cell":"29.7","naive B-cell":"18.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"42","RNA blood lineage specific nTPM":{"B-cells":"29.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"82","RNA cell line specific nTPM":{"lymphoma":"15.4","Myeloma":"5.6"},"RNA tissue cell type enrichment":["Breast - Plasma cells","Lung - B-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"}},{"Gene":"FCRL3","Gene synonym":["CD307c","FCRH3","IFGP3","IRTA3","SPAP2","SPAP2a","SPAP2b","SPAP2c","SPAP2d","SPAP2e"],"Ensembl":"ENSG00000160856","Gene description":"Fc receptor like 3","Uniprot":["Q96P31"],"Chromosome":"1","Position":"157674321-157700769","Protein class":["CD markers","Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"49.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"46.2","Late spermatids":"10.8","NK-cells":"29.1","T-cells":"9.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"35.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"54","RNA blood lineage specific nTPM":{"B-cells":"35.3","NK-cells":"20.4","T-cells":"19.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"67","RNA cell line specific nTPM":{"lymphoma":"14.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - NK-cells (Liver)","Lung - NK-cells (Lung)","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048022"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048022":"AB_2732541"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"}},{"Gene":"FCRL4","Gene synonym":["CD307d","FCRH4","IGFP2","IRTA1"],"Ensembl":"ENSG00000163518","Gene description":"Fc receptor like 4","Uniprot":["Q96PJ5"],"Chromosome":"1","Position":"157573747-157598085","Protein class":["Cancer-related genes","CD markers","Disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lymphoid tissue":"10.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"1.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"1.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054030"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054030":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"}},{"Gene":"FCRL5","Gene synonym":["BXMAS1","CD307e","FCRH5","IRTA2"],"Ensembl":"ENSG00000143297","Gene description":"Fc receptor like 5","Uniprot":["Q96RD9"],"Chromosome":"1","Position":"157513377-157552515","Protein class":["CD markers","Disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"36.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"B-cells":"84.9","Early spermatids":"63.0","Plasma cells":"227.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"17","RNA blood cell specific nTPM":{"memory B-cell":"13.0","naive B-cell":"14.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"B-cells":"14.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"27","RNA cell line specific nTPM":{"lymphoma":"21.2","Myeloma":"7.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Plasma cells","Adipose visceral - Plasma cells","Breast - Plasma cells","Colon - Plasma cells","Heart muscle - Plasma cells","Liver - Plasma cells","Lung - Plasma cells","Pancreas - Plasma cells","Prostate - Plasma cells","Skeletal muscle - Plasma cells","Skin - Plasma cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Plasma cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":169000000,"Blood concentration - Conc. blood MS [pg\/L]":"65000000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"}},{"Gene":"FCRL6","Gene synonym":["FcRH6","FLJ16056","IFGP6"],"Ensembl":"ENSG00000181036","Gene description":"Fc receptor like 6","Uniprot":["Q6DN72"],"Chromosome":"1","Position":"159800511-159816257","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"7.9","lymphoid tissue":"12.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"NK-cells":"107.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"gdT-cell":"142.9","memory CD8 T-cell":"134.3","naive CD8 T-cell":"102.8","NK-cell":"51.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"NK-cells":"51.3","T-cells":"142.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Colon - T-cells","Heart muscle - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"}},{"Gene":"FCRLA","Gene synonym":["FCRL","FCRLb","FCRLc1","FCRLc2","FCRLd","FCRLe","FCRLM1","FCRLX","FREB","MGC4595"],"Ensembl":"ENSG00000132185","Gene description":"Fc receptor like A","Uniprot":["Q7L513"],"Chromosome":"1","Position":"161706972-161714352","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"98.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"131.3","Melanocytes":"34.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"21","RNA cancer specific FPKM":{"melanoma":"38.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"memory B-cell":"368.0","naive B-cell":"341.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"B-cells":"368.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"lymphoma":"179.0","skin cancer":"48.7"},"RNA tissue cell type enrichment":["Skin - Melanocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016545"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016545":"AB_2247037"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"}},{"Gene":"FCSK","Gene synonym":["FLJ39408","FUK"],"Ensembl":"ENSG00000157353","Gene description":"Fucose kinase","Uniprot":["Q8N0W3"],"Chromosome":"16","Position":"70454595-70480274","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041971"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041971":"AB_10795648"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.38e-4"}},{"Gene":"FDFT1","Gene synonym":["SQS"],"Ensembl":"ENSG00000079459","Gene description":"Farnesyl-diphosphate farnesyltransferase 1","Uniprot":["P37268"],"Chromosome":"8","Position":"11795573-11839304","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Multifunctional enzyme","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"472.5","Ionocytes":"400.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008874"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA008874":"AB_1078844"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.92e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.59e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"}},{"Gene":"FDXR","Gene synonym":["ADR","ADXR"],"Ensembl":"ENSG00000161513","Gene description":"Ferredoxin reductase","Uniprot":["P22570"],"Chromosome":"17","Position":"74862497-74873031","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Electron transport","Lipid metabolism","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Deafness","Disease variant","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"adrenal gland":"343.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Granulosa cells":"326.3","Theca cells":"554.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008597","CAB009818","HPA044393","HPA053673"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB008597":"AB_1615557","CAB009818":"AB_2102601","HPA044393":"AB_2678927","HPA053673":"AB_2682225"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.38e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"}},{"Gene":"FER1L5","Gene synonym":["DKFZp434I0121"],"Ensembl":"ENSG00000249715","Gene description":"Fer-1 like family member 5","Uniprot":["A0AVI2"],"Chromosome":"2","Position":"96642737-96704887","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"1.7","testis":"4.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"4.7","Early spermatids":"24.8","Excitatory neurons":"5.4","Late spermatids":"7.5","Spermatocytes":"4.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"}},{"Gene":"FER1L6","Gene synonym":["C8ORFK23"],"Ensembl":"ENSG00000214814","Gene description":"Fer-1 like family member 6","Uniprot":["Q2WGJ9"],"Chromosome":"8","Position":"123851987-124120061","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"intestine":"10.8","stomach 1":"43.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"12.7","Gastric mucus-secreting cells":"31.6","Intestinal goblet cells":"7.6","Late spermatids":"31.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"pancreatic cancer":"4.2","stomach cancer":"5.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.4","pancreatic cancer":"2.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Heart muscle - Cardiomyocytes","Lung - Respiratory ciliated cells","Stomach - Gastric mucous cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054117"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054117":"AB_2682387"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"}},{"Gene":"FEZ1","Gene synonym":["UNC-76"],"Ensembl":"ENSG00000149557","Gene description":"Fasciculation and elongation protein zeta 1","Uniprot":["Q99689"],"Chromosome":"11","Position":"125442881-125592568","Protein class":["Predicted intracellular proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"176.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"92.5","Cardiomyocytes":"138.2","Horizontal cells":"109.6","Melanocytes":"109.7","Oligodendrocytes":"232.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"glioma":"68.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"23.4","MAIT T-cell":"15.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"T-cells":"23.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"27.3"},"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Liver - Sinusoid Endothelial cells","Skin - Fibroblast_2","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038490","HPA076844"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Microtubules","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038490":"AB_10672647","HPA076844":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.06e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.16e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"FEZ2","Gene synonym":[],"Ensembl":"ENSG00000171055","Gene description":"Fasciculation and elongation protein zeta 2","Uniprot":["Q9UHY8"],"Chromosome":"2","Position":"36531805-36646087","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"228.6","Syncytiotrophoblasts":"199.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"15.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035978"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Nucleoli rim","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA035978":"AB_10672235"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.79e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"}},{"Gene":"FFAR1","Gene synonym":["FFA1R","GPR40"],"Ensembl":"ENSG00000126266","Gene description":"Free fatty acid receptor 1","Uniprot":["O14842"],"Chromosome":"19","Position":"35351552-35353862","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"2.8","brain":"4.8","ovary":"2.5","pancreas":"4.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Enteroendocrine cells":"5.9","Pancreatic endocrine cells":"6.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"pancreatic cancer":"2.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"1.3"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048933"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA048933":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"FFAR2","Gene synonym":["FFA2R","GPR43"],"Ensembl":"ENSG00000126262","Gene description":"Free fatty acid receptor 2","Uniprot":["O15552"],"Chromosome":"19","Position":"35443907-35451767","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"20.3","lymphoid tissue":"22.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"33.6","Hofbauer cells":"22.0","Intestinal goblet cells":"15.6","Macrophages":"11.6","monocytes":"42.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"6.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"25","RNA blood cell specific nTPM":{"eosinophil":"85.0","neutrophil":"249.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"38","RNA blood lineage specific nTPM":{"granulocytes":"249.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"2.1","prostate cancer":"3.0"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Heart muscle - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2","Skeletal muscle - Neutrophils","Stomach - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023985"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023985":"AB_1849302"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"}},{"Gene":"FFAR3","Gene synonym":["FFA3R","GPR41"],"Ensembl":"ENSG00000185897","Gene description":"Free fatty acid receptor 3","Uniprot":["O14843"],"Chromosome":"19","Position":"35358460-35360489","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"4.1","lymphoid tissue":"2.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"15.5","granulocytes":"3.1","Macrophages":"7.0","monocytes":"14.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"eosinophil":"2.5","neutrophil":"2.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"2.8"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044681"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044681":"AB_2679043"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"}},{"Gene":"FFAR4","Gene synonym":["GPR120","GPR129","O3FAR1","PGR4"],"Ensembl":"ENSG00000186188","Gene description":"Free fatty acid receptor 4","Uniprot":["Q5NUL3"],"Chromosome":"10","Position":"93566665-93604480","Protein class":["FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Inflammatory response"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"11.4","pituitary gland":"11.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"27.7","Intestinal goblet cells":"65.6","Late spermatids":"19.4","Pancreatic endocrine cells":"22.3","Paneth cells":"13.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"4.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"3.9","pancreatic cancer":"2.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Colon - Colon enterocytes","Testis - Late spermatids","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042563"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA042563":"AB_10794762"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"}},{"Gene":"FGF6","Gene synonym":[],"Ensembl":"ENSG00000111241","Gene description":"Fibroblast growth factor 6","Uniprot":["P10767"],"Chromosome":"12","Position":"4428155-4445614","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Angiogenesis","Differentiation"],"Molecular function":["Developmental protein","Growth factor","Mitogen"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"20","RNA tissue specific nTPM":{"skeletal muscle":"16.0","tongue":"11.5"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Leukemia":"3.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"FGFR1","Gene synonym":["BFGFR","CD331","CEK","FLG","FLT2","H2","H3","H4","H5","KAL2","N-SAM"],"Ensembl":"ENSG00000077782","Gene description":"Fibroblast growth factor receptor 1","Uniprot":["P11362"],"Chromosome":"8","Position":"38400215-38468834","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins","Transporters"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Heparin-binding","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Craniosynostosis","Disease variant","Dwarfism","FDA approved drug targets","Holoprosencephaly","Hypogonadotropic hypogonadism","Intellectual disability","Kallmann syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"179.2","Leydig cells":"196.8","Oligodendrocyte precursor cells":"159.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"202.8"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033614","HPA056402"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"78000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033614":"AB_783377","HPA056402":"AB_2683118"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"}},{"Gene":"FGFR2","Gene synonym":["BEK","CD332","CEK3","CFD1","ECT1","JWS","K-SAM","KGFR","TK14","TK25"],"Ensembl":"ENSG00000066468","Gene description":"Fibroblast growth factor receptor 2","Uniprot":["P21802"],"Chromosome":"10","Position":"121478332-121598458","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Apoptosis"],"Molecular function":["Heparin-binding","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Craniosynostosis","Disease variant","Ectodermal dysplasia","FDA approved drug targets","Intellectual disability","Lacrimo-auriculo-dento-digital syndrome","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"273.8","choroid plexus":"198.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"221.1","Cholangiocytes":"192.5","Oligodendrocytes":"531.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"24","RNA blood cell specific nTPM":{"basophil":"13.2","eosinophil":"3.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"58","RNA blood lineage specific nTPM":{"granulocytes":"13.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"215.7"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Keratinocyte (other)","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010886","HPA035305"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cell Junctions"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 26: NCI-H716 - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"CAB010886":"AB_259379","HPA035305":"AB_10672862"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.79e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.32e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"}},{"Gene":"FGFR3","Gene synonym":["ACH","CD333","CEK2","JTK4"],"Ensembl":"ENSG00000068078","Gene description":"Fibroblast growth factor receptor 3","Uniprot":["P22607"],"Chromosome":"4","Position":"1793293-1808872","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Apoptosis"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Craniosynostosis","Deafness","Disease variant","Dwarfism","Ectodermal dysplasia","FDA approved drug targets","Lacrimo-auriculo-dento-digital syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"148.3","esophagus":"139.7","skin 1":"271.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"397.6","Basal keratinocytes":"99.4","Cholangiocytes":"71.2","Suprabasal keratinocytes":"97.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"149.7"},"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004231","HPA067204"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2500000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB004231":"AB_627596","HPA067204":"AB_2685804"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.77e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"}},{"Gene":"FGFR4","Gene synonym":["CD334","JTK2"],"Ensembl":"ENSG00000160867","Gene description":"Fibroblast growth factor receptor 4","Uniprot":["P22455"],"Chromosome":"5","Position":"177086905-177098144","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins","Transporters"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"82.5","lung":"65.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"61.6","Hepatocytes":"23.6","Theca cells":"30.1","Undifferentiated cells":"35.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"42.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"102.2"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005196","HPA027273","HPA027369","HPA028251"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB005196":"AB_631512","HPA027273":"AB_10600212","HPA027369":"AB_10599427","HPA028251":"AB_10601221"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"}},{"Gene":"FGGY","Gene synonym":["FLJ10986"],"Ensembl":"ENSG00000172456","Gene description":"FGGY carbohydrate kinase domain containing","Uniprot":["Q96C11"],"Chromosome":"1","Position":"59296638-59810647","Protein class":["Disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Amyotrophic lateral sclerosis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"77.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"122.6","Cholangiocytes":"348.4","Hepatocytes":"163.3","Skeletal myocytes":"201.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"13.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054971","HPA075137"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA054971":null,"HPA075137":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"}},{"Gene":"FGL2","Gene synonym":["pT49","T49"],"Ensembl":"ENSG00000127951","Gene description":"Fibrinogen like 2","Uniprot":["Q14314"],"Chromosome":"7","Position":"77193369-77199848","Protein class":["Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"162.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"454.0","Langerhans cells":"682.1","Macrophages":"488.9","monocytes":"1004.2","Schwann cells":"290.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"45","RNA blood cell specific nTPM":{"classical monocyte":"256.5","eosinophil":"226.3","intermediate monocyte":"380.6","myeloid DC":"160.0","neutrophil":"294.7","non-classical monocyte":"379.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"59","RNA blood lineage specific nTPM":{"dendritic cells":"160.0","granulocytes":"294.7","monocytes":"380.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"breast cancer":"7.9","skin cancer":"19.5"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021011","HPA026682"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":38800000,"Blood concentration - Conc. blood MS [pg\/L]":"7800000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021011":"AB_1848532","HPA026682":"AB_1848533"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"}},{"Gene":"FIBCD1","Gene synonym":["FLJ14810"],"Ensembl":"ENSG00000130720","Gene description":"Fibrinogen C domain containing 1","Uniprot":["Q8N539"],"Chromosome":"9","Position":"130902438-130939286","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"9.9","brain":"26.7","parathyroid gland":"12.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"10.8","Early spermatids":"20.6","Horizontal cells":"12.8","Intestinal goblet cells":"17.1","Late spermatids":"33.8","Spermatogonia":"17.0","Undifferentiated cells":"13.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"non-classical monocyte":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"monocytes":"1.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"22.6"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"17.6","hippocampal formation":"68.4"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"hippocampal formation":"57.3"},"Antibody":["HPA055353"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA055353":"AB_2682791"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"}},{"Gene":"FIG4","Gene synonym":["ALS11","CMT4J","dJ249I4.1","hSac3","KIAA0274","SAC3"],"Ensembl":"ENSG00000112367","Gene description":"FIG4 phosphoinositide 5-phosphatase","Uniprot":["Q92562"],"Chromosome":"6","Position":"109690609-109878098","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Amyotrophic lateral sclerosis","Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017823","HPA068859"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Vesicles","Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"CAB017823":null,"HPA068859":"AB_2686049"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.91e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.42e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.73e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"}},{"Gene":"FIS1","Gene synonym":["CGI-135","H_NH0132A01.6","TTC11"],"Ensembl":"ENSG00000214253","Gene description":"Fission, mitochondrial 1","Uniprot":["Q9Y3D6"],"Chromosome":"7","Position":"101239458-101252316","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"880.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017430"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA017430":"AB_1848608"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"}},{"Gene":"FITM1","Gene synonym":["FIT1"],"Ensembl":"ENSG00000139914","Gene description":"Fat storage inducing transmembrane protein 1","Uniprot":["A5D6W6"],"Chromosome":"14","Position":"24130659-24132849","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"heart muscle":"171.1","skeletal muscle":"224.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"276.5","Skeletal myocytes":"276.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019842"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019842":"AB_1853025"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-7"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.00e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"}},{"Gene":"FITM2","Gene synonym":["C20orf142","dJ881L22.2","FIT2"],"Ensembl":"ENSG00000197296","Gene description":"Fat storage inducing transmembrane protein 2","Uniprot":["Q8N6M3"],"Chromosome":"20","Position":"44302840-44311202","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Deafness","Disease variant","Dystonia","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"67.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Cardiomyocytes":"161.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Skin - Sebaceous gland cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.98e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"}},{"Gene":"FKBP11","Gene synonym":["FKBP19"],"Ensembl":"ENSG00000134285","Gene description":"FKBP prolyl isomerase 11","Uniprot":["Q9NYL4"],"Chromosome":"12","Position":"48921518-48926474","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Isomerase","Rotamase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"495.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Plasma cells":"1347.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"188.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"360.1"},"RNA tissue cell type enrichment":["Breast - Plasma cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041709"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA041709":"AB_10794487"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.09e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"}},{"Gene":"FKBP1A","Gene synonym":["FKBP-12","FKBP1","FKBP12","FKBP12C","PKC12","PPIASE"],"Ensembl":"ENSG00000088832","Gene description":"FKBP prolyl isomerase 1A","Uniprot":["P62942"],"Chromosome":"20","Position":"1368977-1393164","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Isomerase","Rotamase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Paneth cells":"1156.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"675.2","granulocytes":"974.2","monocytes":"1013.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Kidney - Endothelial cells","Lung - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004639","HPA051798"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004639":"AB_425434","HPA051798":"AB_2681615"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.44e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.69e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"}},{"Gene":"FKBP2","Gene synonym":["FKBP-13","FKBP13","PPIase"],"Ensembl":"ENSG00000173486","Gene description":"FKBP prolyl isomerase 2","Uniprot":["P26885"],"Chromosome":"11","Position":"64241003-64244132","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase","Rotamase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"506.2","Proximal tubular cells":"192.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"929.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025561","HPA049405"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"510000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB025561":null,"HPA049405":"AB_2680749"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"}},{"Gene":"FKBP8","Gene synonym":["FKBP38","FKBPr38"],"Ensembl":"ENSG00000105701","Gene description":"FKBP prolyl isomerase 8","Uniprot":["Q14318"],"Chromosome":"19","Position":"18531751-18544077","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":["Isomerase","Rotamase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"1202.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"eosinophil":"93.4","neutrophil":"78.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"93.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025346","HPA045177"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Endoplasmic reticulum","Cytosol"],"Antibody RRID":{"CAB025346":null,"HPA045177":"AB_2679244"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.76e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"}},{"Gene":"FKRP","Gene synonym":["FKTR","LGMD2I","MDC1C"],"Ensembl":"ENSG00000181027","Gene description":"Fukutin related protein","Uniprot":["Q9H9S5"],"Chromosome":"19","Position":"46746046-46776988","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Cardiomyopathy","Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Limb-girdle muscular dystrophy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043115","HPA060454"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043115":"AB_2678324","HPA060454":"AB_2684281"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.98e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"}},{"Gene":"FLII","Gene synonym":["FLI","Fli1","FLIL","MGC39265"],"Ensembl":"ENSG00000177731","Gene description":"FLII actin remodeling protein","Uniprot":["Q13045"],"Chromosome":"17","Position":"18244815-18258738","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Actin-binding","Activator","Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"245.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007084","HPA008903","CAB016132"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm","Centriolar satellite","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB016132":"AB_627613","HPA007084":"AB_1848638","HPA008903":"AB_1848640"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"}},{"Gene":"FLOT2","Gene synonym":["ECS-1","ECS1","ESA","ESA1","M17S1"],"Ensembl":"ENSG00000132589","Gene description":"Flotillin 2","Uniprot":["Q14254"],"Chromosome":"17","Position":"28879335-28897733","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001396","CAB004395","HPA071038"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB004395":"AB_627618","HPA001396":"AB_1078894","HPA071038":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"}},{"Gene":"FLRT1","Gene synonym":["MGC21624","SPG68"],"Ensembl":"ENSG00000126500","Gene description":"Fibronectin leucine rich transmembrane protein 1","Uniprot":[],"Chromosome":"11","Position":"64103188-64119173","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"8.7","Horizontal cells":"7.7","Inhibitory neurons":"15.7","Muller glia cells":"5.8","Oligodendrocyte precursor cells":"30.8","Oligodendrocytes":"12.4","Schwann cells":"9.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"5.6"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Kidney - Ascending Loop of Henle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054589"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054589":"AB_2682533"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"}},{"Gene":"FLRT2","Gene synonym":[],"Ensembl":"ENSG00000185070","Gene description":"Fibronectin leucine rich transmembrane protein 2","Uniprot":["O43155"],"Chromosome":"14","Position":"85530144-85654428","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"29.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"270.8","Excitatory neurons":"542.5","Inhibitory neurons":"313.2","Leydig cells":"214.3","Microglial cells":"421.4","Oligodendrocyte precursor cells":"203.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"basal ganglia":"2.1","cerebral cortex":"8.2","hippocampal formation":"4.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"23.8"},"RNA tissue cell type enrichment":["Colon - Fibroblasts","Lung - Fibroblast_2","Prostate - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-5"}},{"Gene":"FLRT3","Gene synonym":[],"Ensembl":"ENSG00000125848","Gene description":"Fibronectin leucine rich transmembrane protein 3","Uniprot":["Q9NZU0"],"Chromosome":"20","Position":"14322985-14337614","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism","Kallmann syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"23.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"231.7","Alveolar cells type 2":"155.9","Basal prostatic cells":"70.1","Thymic epithelial cells":"72.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 2","Prostate - Prostate basal glandular cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056033"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions","Cytosol"],"Antibody RRID":{"HPA056033":"AB_2683016"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.85e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.54e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.49e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"}},{"Gene":"FLT1","Gene synonym":["FLT","VEGFR1"],"Ensembl":"ENSG00000102755","Gene description":"Fms related receptor tyrosine kinase 1","Uniprot":["P17948"],"Chromosome":"13","Position":"28300346-28495145","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Angiogenesis","Chemotaxis","Differentiation"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"placenta":"432.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"388.4","Endothelial cells":"349.0","Extravillous trophoblasts":"987.3","Microglial cells":"422.3","Syncytiotrophoblasts":"1141.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"28.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"15.9","testis cancer":"44.4"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Skin - Endothelial cells","Stomach - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011740","HPA014290","CAB068189","CAB068190"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":876000,"Blood concentration - Conc. blood MS [pg\/L]":"87000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB068189":"AB_2665636","CAB068190":"AB_2665637","HPA011740":"AB_1858737","HPA014290":"AB_1858738"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"}},{"Gene":"FLT3","Gene synonym":["CD135","FLK2","STK1"],"Ensembl":"ENSG00000122025","Gene description":"Fms related receptor tyrosine kinase 3","Uniprot":["P36888"],"Chromosome":"13","Position":"28003274-28100592","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"5.3","brain":"4.9","lymphoid tissue":"6.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"dendritic cells":"60.8","Inhibitory neurons":"58.6","Kupffer cells":"51.4","Langerhans cells":"21.3","Macrophages":"18.4","monocytes":"18.2","Schwann cells":"52.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"1.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"4.9"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"myeloid DC":"68.7","plasmacytoid DC":"26.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"68.7"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"66","RNA cell line specific nTPM":{"Leukemia":"29.2"},"RNA tissue cell type enrichment":["Prostate - Macrophages","Stomach - Macrophages","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047539"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA047539":"AB_2680080"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"}},{"Gene":"FLT3LG","Gene synonym":[],"Ensembl":"ENSG00000090554","Gene description":"Fms related receptor tyrosine kinase 3 ligand","Uniprot":["P49771"],"Chromosome":"19","Position":"49474207-49486231","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"19.5","T-cells":"52.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"77.8","MAIT T-cell":"144.4","memory CD4 T-cell":"158.2","memory CD8 T-cell":"102.0","naive CD4 T-cell":"169.7","naive CD8 T-cell":"137.8","T-reg":"171.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"171.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.17e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"}},{"Gene":"FLT4","Gene synonym":["PCL","VEGFR-3","VEGFR3"],"Ensembl":"ENSG00000037280","Gene description":"Fms related receptor tyrosine kinase 4","Uniprot":["P35916"],"Chromosome":"5","Position":"180601506-180649624","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Angiogenesis"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Adipocytes":"23.7","Endothelial cells":"36.2","Extravillous trophoblasts":"40.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"MAIT T-cell":"3.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"31","RNA blood lineage specific nTPM":{"T-cells":"3.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"6.0"},"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000099","HPA046519","HPA067906","HPA074389"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Plasma membrane","Cell Junctions"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":20000000,"Blood concentration - Conc. blood MS [pg\/L]":"290000000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nuclear speckles","Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"CAB000099":null,"HPA046519":"AB_2732527","HPA067906":"AB_2732775","HPA074389":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"FLVCR1","Gene synonym":["AXPC1","FLVCR","MFSD7B","PCA","SLC49A1"],"Ensembl":"ENSG00000162769","Gene description":"FLVCR heme transporter 1","Uniprot":["Q9Y5Y0"],"Chromosome":"1","Position":"212858275-212899363","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Erythrocyte maturation","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"19.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"49.1","Proximal enterocytes":"56.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046646"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA046646":"AB_2679735"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"}},{"Gene":"FLVCR2","Gene synonym":["C14orf58","CCT","FLJ20371","MFSD7C","SLC49A2"],"Ensembl":"ENSG00000119686","Gene description":"FLVCR heme transporter 2","Uniprot":["Q9UPI3"],"Chromosome":"14","Position":"75578620-75663214","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"72.1","Late spermatids":"141.5","Microglial cells":"40.1","Proximal enterocytes":"42.1","Syncytiotrophoblasts":"62.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"classical monocyte":"14.0","intermediate monocyte":"14.6","myeloid DC":"7.6","non-classical monocyte":"11.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"7.6","monocytes":"14.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037984"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037984":"AB_10672733"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.53e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"}},{"Gene":"FMNL1","Gene synonym":["C17orf1","C17orf1B","FMNL"],"Ensembl":"ENSG00000184922","Gene description":"Formin like 1","Uniprot":["O95466"],"Chromosome":"17","Position":"45221444-45247319","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"277.6","lymphoid tissue":"104.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"102.2","dendritic cells":"123.8","Kupffer cells":"94.2","Langerhans cells":"178.4","Macrophages":"113.9","monocytes":"208.5","NK-cells":"191.6","Schwann cells":"91.4","T-cells":"134.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"72.1","lymphoma":"88.8","Myeloma":"125.1"},"RNA tissue cell type enrichment":["Kidney - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008129","HPA028288"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008129":"AB_1848963","HPA028288":"AB_10612110"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.23e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"}},{"Gene":"FMO1","Gene synonym":[],"Ensembl":"ENSG00000010932","Gene description":"Flavin containing dimethylaniline monoxygenase 1","Uniprot":["Q01740"],"Chromosome":"1","Position":"171248471-171285978","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"kidney":"199.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"28.0","Proximal enterocytes":"87.2","Proximal tubular cells":"166.7","Thymic epithelial cells":"60.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"renal cancer":"18.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"1.4"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Lung - Fibroblast_2","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078132"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078132":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.81e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"FMO2","Gene synonym":[],"Ensembl":"ENSG00000094963","Gene description":"Flavin containing dimethylaniline monoxygenase 2","Uniprot":["Q99518"],"Chromosome":"1","Position":"171185249-171212686","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"69.7","lung":"93.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"190.6","Alveolar cells type 1":"116.9","Breast myoepithelial cells":"85.4","Club cells":"75.5","Endothelial cells":"90.3","Fibroblasts":"114.6","Mucus glandular cells":"81.6","Salivary duct cells":"110.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Fibroblast_1","Pancreas - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028261"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA028261":"AB_10601012"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"}},{"Gene":"FMO3","Gene synonym":["FMOII"],"Ensembl":"ENSG00000007933","Gene description":"Flavin containing dimethylaniline monoxygenase 3","Uniprot":["P31513"],"Chromosome":"1","Position":"171090901-171117819","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"41","RNA tissue specific nTPM":{"liver":"1123.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"31","RNA single cell type specific nTPM":{"Hepatocytes":"411.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"liver cancer":"94.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"3.5"},"RNA tissue cell type enrichment":["Colon - Endothelial cells","Liver - Hepatocytes","Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013750"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013750":"AB_1848968"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.46e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.60e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"}},{"Gene":"FMO4","Gene synonym":["FMO2"],"Ensembl":"ENSG00000076258","Gene description":"Flavin containing dimethylaniline monoxygenase 4","Uniprot":["P31512"],"Chromosome":"1","Position":"171314183-171342084","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"kidney":"48.6","liver":"61.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"22.8","Oligodendrocytes":"17.5","Proximal enterocytes":"16.1","Proximal tubular cells":"52.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049100","HPA072438"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA049100":"AB_2680629","HPA072438":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.45e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"}},{"Gene":"FMO5","Gene synonym":[],"Ensembl":"ENSG00000131781","Gene description":"Flavin containing dimethylaniline monoxygenase 5","Uniprot":["P49326"],"Chromosome":"1","Position":"147175351-147243050","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"683.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"89.6","Cholangiocytes":"123.2","Hepatocytes":"248.3","Intestinal goblet cells":"58.1","Proximal enterocytes":"94.8","Proximal tubular cells":"62.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"liver cancer":"43.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"9.8"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Liver - Hepatocytes","Lung - Alveolar cells type 2","Skin - Eccrine sweat gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012373"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA012373":"AB_1848975"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.34e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"}},{"Gene":"FMR1NB","Gene synonym":["CT37","FLJ25736","NY-SAR-35"],"Ensembl":"ENSG00000176988","Gene description":"FMR1 neighbor","Uniprot":["Q8N0W7"],"Chromosome":"X","Position":"147981337-148026665","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"333","RNA tissue specific nTPM":{"testis":"58.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Spermatocytes":"563.7","Spermatogonia":"234.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Bile duct cancer":"40.2","Myeloma":"15.5"},"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011284","CAB026403"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026403":null,"HPA011284":"AB_1078898"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"}},{"Gene":"FNDC10","Gene synonym":["C1orf233"],"Ensembl":"ENSG00000228594","Gene description":"Fibronectin type III domain containing 10","Uniprot":["F2Z333"],"Chromosome":"1","Position":"1598012-1600135","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"25.4","brain":"24.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"56.4","Horizontal cells":"23.7","Theca cells":"34.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Macrophages","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"}},{"Gene":"FNDC3A","Gene synonym":["bA203I16.5","FNDC3","KIAA0970"],"Ensembl":"ENSG00000102531","Gene description":"Fibronectin type III domain containing 3A","Uniprot":["Q9Y2H6"],"Chromosome":"13","Position":"48975912-49209779","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008927","HPA012555","HPA012825"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Golgi apparatus","Centrosome"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA008927":"AB_1078899","HPA012555":null,"HPA012825":"AB_1848985"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"}},{"Gene":"FNDC3B","Gene synonym":["DKFZp762K137","FAD104","FLJ23399","PRO4979","YVTM2421"],"Ensembl":"ENSG00000075420","Gene description":"Fibronectin type III domain containing 3B","Uniprot":["Q53EP0"],"Chromosome":"3","Position":"172039578-172401669","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"278.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"29.4","hypothalamus":"8.2","pons":"9.4","thalamus":"14.4"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"37.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"37.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007859"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 34: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA007859":"AB_1078900"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.41e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.94e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.85e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.06e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.65e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"}},{"Gene":"FNDC4","Gene synonym":["FLJ22362","FRCP1"],"Ensembl":"ENSG00000115226","Gene description":"Fibronectin type III domain containing 4","Uniprot":["Q9H6D8"],"Chromosome":"2","Position":"27491883-27495200","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"124.2","liver":"126.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"187.3","Hepatocytes":"135.0","Late spermatids":"623.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"39.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"16.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051804","HPA063581"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Aggresome","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Aggresome","Cytosol"],"Antibody RRID":{"HPA051804":"AB_2681617","HPA063581":"AB_2685048"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.07e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.11e-4"}},{"Gene":"FNDC5","Gene synonym":["FRCP2"],"Ensembl":"ENSG00000160097","Gene description":"Fibronectin type III domain containing 5","Uniprot":["Q8NAU1"],"Chromosome":"1","Position":"32862268-32872482","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hormone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"skeletal muscle":"323.1","tongue":"478.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"53.7","Cardiomyocytes":"84.0","Granulosa cells":"35.5","Horizontal cells":"44.9","Muller glia cells":"40.4","Serous glandular cells":"35.2","Skeletal myocytes":"46.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"4.2","liver cancer":"10.0","testis cancer":"14.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"22.3","Sarcoma":"37.7"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051290"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051290":"AB_2681422"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"}},{"Gene":"FNDC9","Gene synonym":["C5orf40","MGC27121"],"Ensembl":"ENSG00000172568","Gene description":"Fibronectin type III domain containing 9","Uniprot":["Q8TBE3"],"Chromosome":"5","Position":"157341598-157345677","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"36.8","pituitary gland":"11.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1.1","Inhibitory neurons":"1.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"16","RNA cancer specific FPKM":{"glioma":"0.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hypothalamus":"36.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"}},{"Gene":"FO681492.1","Gene synonym":[],"Ensembl":"ENSG00000277758","Gene description":"Synaptotagmin-15","Uniprot":[],"Chromosome":"10","Position":"47749758-47763592","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.3","lung":"12.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"2.5","Alveolar cells type 1":"10.9","Alveolar cells type 2":"6.0","Endothelial cells":"4.1","Melanocytes":"1.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"11.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"5.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036971","HPA036972","HPA064559"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA036971":"AB_2675406","HPA036972":"AB_2675407","HPA064559":"AB_2685286"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"}},{"Gene":"FOCAD","Gene synonym":["FLJ20375","KIAA1797"],"Ensembl":"ENSG00000188352","Gene description":"Focadhesin","Uniprot":["Q5VW36"],"Chromosome":"9","Position":"20658309-20995955","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"choroid plexus":"154.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"522.0","Inhibitory neurons":"307.3","Oligodendrocyte precursor cells":"134.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055015"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA055015":"AB_2682673"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.25e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.41e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.09e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"}},{"Gene":"FOLH1","Gene synonym":["FOLH","GCP2","GCPII","NAALAD1","NAALAdase","PSM","PSMA"],"Ensembl":"ENSG00000086205","Gene description":"Folate hydrolase 1","Uniprot":["Q04609"],"Chromosome":"11","Position":"49145092-49208638","Protein class":["Cancer-related genes","Enzymes","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Dipeptidase","Hydrolase","Metalloprotease","Multifunctional enzyme","Protease"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"266.4","prostate":"76.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Oligodendrocytes":"347.0","Prostatic glandular cells":"556.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"27","RNA cancer specific FPKM":{"prostate cancer":"142.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"51","RNA cell line specific nTPM":{"prostate cancer":"223.1","Rhabdoid":"170.8"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Lung - Fibroblast_1","Pancreas - Fibroblasts","Prostate - Prostate glandular cells","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001451","HPA010593"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001451":"AB_563979","HPA010593":"AB_1079685"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.24e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.30e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"}},{"Gene":"FOLR1","Gene synonym":["FOLR","FR\u00c3\u017d\u00c2\u00b1"],"Ensembl":"ENSG00000110195","Gene description":"Folate receptor alpha","Uniprot":["P15328"],"Chromosome":"11","Position":"72189558-72196323","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"480.2","fallopian tube":"187.2","lung":"193.5","salivary gland":"219.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"392.0","Alveolar cells type 2":"262.4","Breast glandular cells":"225.7","Club cells":"188.5","Collecting duct cells":"257.9","Cytotrophoblasts":"473.3","Proximal tubular cells":"247.5","Syncytiotrophoblasts":"328.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"259.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"137.8","ovarian cancer":"122.5"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Lung - Alveolar cells type 1","Skin - Eccrine sweat gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077030"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":448000,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA077030":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.50e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"}},{"Gene":"FOLR2","Gene synonym":["FR\u00c3\u017d\u00c2\u00b2"],"Ensembl":"ENSG00000165457","Gene description":"Folate receptor beta","Uniprot":["P14207"],"Chromosome":"11","Position":"72216601-72221950","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"168.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hofbauer cells":"997.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"64.2","intermediate monocyte":"50.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"18.7","monocytes":"64.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"3.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Skeletal muscle - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.42e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.41e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-3"}},{"Gene":"FOSL2","Gene synonym":["FLJ23306","FRA2"],"Ensembl":"ENSG00000075426","Gene description":"FOS like 2, AP-1 transcription factor subunit","Uniprot":["P15408"],"Chromosome":"2","Position":"28392448-28417317","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"352.1","monocytes":"383.4","NK-cells":"324.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"36.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Neutrophils"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004817","CAB013460","HPA061417"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB013460":null,"HPA004817":"AB_1849014","HPA061417":"AB_2684509"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"}},{"Gene":"FOXK2","Gene synonym":["ILF","ILF1"],"Ensembl":"ENSG00000141568","Gene description":"Forkhead box K2","Uniprot":["Q01167"],"Chromosome":"17","Position":"82519713-82644662","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027523","HPA073491"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Mitochondria"],"Antibody RRID":{"HPA027523":"AB_10601013","HPA073491":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"}},{"Gene":"FOXM1","Gene synonym":["FKHL16","HFH-11","HNF-3","INS-1","MPHOSPH2","MPP2","TGT3","trident"],"Ensembl":"ENSG00000111206","Gene description":"Forkhead box M1","Uniprot":["Q08050"],"Chromosome":"12","Position":"2857680-2877174","Protein class":["Cancer-related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Cell cycle","DNA damage","DNA repair","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"25.0","lymphoid tissue":"32.2","testis":"21.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"22.2","Erythroid cells":"20.7","Extravillous trophoblasts":"18.5","Granulosa cells":"16.5","Late spermatids":"23.4","Plasma cells":"25.6","Undifferentiated cells":"22.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Mitotic cells (Heart)","Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017832"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm","Nucleoli","Nucleoli rim"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB017832":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.95e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.92e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"}},{"Gene":"FOXRED1","Gene synonym":["H17"],"Ensembl":"ENSG00000110074","Gene description":"FAD dependent oxidoreductase domain containing 1","Uniprot":["Q96CU9"],"Chromosome":"11","Position":"126269055-126278131","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039620","HPA046192"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA039620":"AB_2676602","HPA046192":"AB_2679580"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.36e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.01e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"}},{"Gene":"FP565260.3","Gene synonym":[],"Ensembl":"ENSG00000277117","Gene description":"ICOS ligand","Uniprot":[],"Chromosome":"21","Position":"5022493-5040666","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1.7","dendritic cells":"2.6","Gastric mucus-secreting cells":"1.8","Langerhans cells":"1.4","Microglial cells":"2.7","Oligodendrocytes":"1.8","Plasma cells":"1.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"2.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029179"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Plasma membrane","Cytoplasmic bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA029179":"AB_2732445"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"}},{"Gene":"FPR1","Gene synonym":["FMLP","FPR"],"Ensembl":"ENSG00000171051","Gene description":"Formyl peptide receptor 1","Uniprot":["P21462"],"Chromosome":"19","Position":"51745172-51804110","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Chemotaxis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"195.3","lymphoid tissue":"166.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Hofbauer cells":"209.6","Kupffer cells":"392.0","Macrophages":"159.5","monocytes":"470.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"23.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"4199.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"4199.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Macrophages","Colon - Neutrophils","Kidney - Macrophages","Liver - Neutrophils","Lung - Neutrophil_2","Prostate - Macrophages","Skeletal muscle - Neutrophils","Skin - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046550","HPA061744"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Nucleoli"],"Antibody RRID":{"HPA046550":"AB_2679694","HPA061744":"AB_2684600"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-3"}},{"Gene":"FPR2","Gene synonym":["ALXR","FMLP-R-II","FMLPX","FPR2A","FPRH2","FPRL1","HM63","LXA4R"],"Ensembl":"ENSG00000171049","Gene description":"Formyl peptide receptor 2","Uniprot":["P25090"],"Chromosome":"19","Position":"51752026-51770531","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Chemotaxis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"56.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"monocytes":"410.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"neutrophil":"1187.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"1187.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bladder cancer":"2.7","Leukemia":"2.7","liver cancer":"2.2"},"RNA tissue cell type enrichment":["Colon - Neutrophils","Heart muscle - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2","Skeletal muscle - Neutrophils","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029154"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029154":"AB_10602133"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"}},{"Gene":"FPR3","Gene synonym":["FMLPY","FPRH1","FPRL2","RMLP-R-I"],"Ensembl":"ENSG00000187474","Gene description":"Formyl peptide receptor 3","Uniprot":["P25089"],"Chromosome":"19","Position":"51795157-51826190","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Chemotaxis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"28.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"64.2","Kupffer cells":"29.6","Langerhans cells":"301.0","Macrophages":"98.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"20","RNA blood cell specific nTPM":{"classical monocyte":"2.3","intermediate monocyte":"6.7","myeloid DC":"2.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"44","RNA blood lineage specific nTPM":{"dendritic cells":"2.4","monocytes":"6.7"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Gastric cancer":"6.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.13e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"}},{"Gene":"FRAS1","Gene synonym":["FLJ14927","FLJ22031","KIAA1500"],"Ensembl":"ENSG00000138759","Gene description":"Fraser extracellular matrix complex subunit 1","Uniprot":["Q86XX4"],"Chromosome":"4","Position":"78057323-78544269","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"13.8","thyroid gland":"12.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Excitatory neurons":"201.6","Inhibitory neurons":"369.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051601"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051601":"AB_2681547"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"}},{"Gene":"FREM2","Gene synonym":["DKFZp686J0811"],"Ensembl":"ENSG00000150893","Gene description":"FRAS1 related extracellular matrix 2","Uniprot":["Q5SZK8"],"Chromosome":"13","Position":"38687077-38887131","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"7.7","thyroid gland":"4.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"18.5","Astrocytes":"44.6","Cholangiocytes":"15.4","Endometrial ciliated cells":"15.8","Glandular and luminal cells":"42.9","Proximal tubular cells":"19.8","Skeletal myocytes":"46.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"testis cancer":"29.7"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028831"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028831":"AB_10603668"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.23e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"}},{"Gene":"FRMD3","Gene synonym":["EPB41L4O","MGC20553"],"Ensembl":"ENSG00000172159","Gene description":"FERM domain containing 3","Uniprot":["A2A2Y4"],"Chromosome":"9","Position":"83242990-83538546","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"85.0","skeletal muscle":"81.2","tongue":"74.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"94.6","Cardiomyocytes":"80.6","Cone photoreceptor cells":"108.6","Early spermatids":"97.7","Inhibitory neurons":"68.1","Late spermatids":"142.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"27.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"2.0","intermediate monocyte":"3.4","neutrophil":"2.5","non-classical monocyte":"1.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"2.5","monocytes":"3.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Enteric glia cells","Prostate - Endothelial cells","Skin - Endothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017285"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA017285":"AB_2669569"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.79e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-3"}},{"Gene":"FRMD5","Gene synonym":["MGC14161"],"Ensembl":"ENSG00000171877","Gene description":"FERM domain containing 5","Uniprot":["Q7Z6J6"],"Chromosome":"15","Position":"43870761-44195271","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"38.7","heart muscle":"46.6","retina":"20.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"370.3","Inhibitory neurons":"632.1","Oligodendrocyte precursor cells":"285.9","Oligodendrocytes":"1888.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"6.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.89e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"}},{"Gene":"FRRS1","Gene synonym":["SDFR2","SDR2"],"Ensembl":"ENSG00000156869","Gene description":"Ferric chelate reductase 1","Uniprot":["Q6ZNA5"],"Chromosome":"1","Position":"99703970-99766635","Protein class":["Predicted membrane proteins"],"Biological process":["Electron transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"28.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"30.8","Hepatocytes":"46.0","Syncytiotrophoblasts":"35.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"eosinophil":"12.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"12.6"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Gallbladder cancer":"78.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017883"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017883":"AB_2294223"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.53e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"}},{"Gene":"FRRS1L","Gene synonym":["C9orf4","CG-6"],"Ensembl":"ENSG00000260230","Gene description":"Ferric chelate reductase 1 like","Uniprot":["Q9P0K9"],"Chromosome":"9","Position":"109130293-109167249","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.6","ovary":"11.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"57.7","Early spermatids":"32.7","Excitatory neurons":"90.3","Horizontal cells":"125.6","Inhibitory neurons":"79.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"2.3"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071086"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA071086":"AB_2686342"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"}},{"Gene":"FSCN2","Gene synonym":["RFSN","RP30"],"Ensembl":"ENSG00000186765","Gene description":"Fascin actin-bundling protein 2, retinal","Uniprot":["O14926"],"Chromosome":"17","Position":"81528377-81537130","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"4.5","retina":"8.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"5.2","Cone photoreceptor cells":"22.4","Exocrine glandular cells":"5.6","Rod photoreceptor cells":"22.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079270"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA079270":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"}},{"Gene":"FSD1L","Gene synonym":["CCDC10","CSDUFD1","FSD1CL","FSD1NL"],"Ensembl":"ENSG00000106701","Gene description":"Fibronectin type III and SPRY domain containing 1 like","Uniprot":["Q9BXM9"],"Chromosome":"9","Position":"105447796-105552433","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"43.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"253.3","Early spermatids":"85.0","Excitatory neurons":"77.8","Late spermatids":"85.9","Rod photoreceptor cells":"135.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Ductal cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035138"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"HPA035138":"AB_10601324"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"}},{"Gene":"FSHR","Gene synonym":["FSHRO","LGR1","ODG1"],"Ensembl":"ENSG00000170820","Gene description":"Follicle stimulating hormone receptor","Uniprot":["P23945"],"Chromosome":"2","Position":"48962157-49154527","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"1.0","ovary":"2.0","testis":"2.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"9.9","Granulosa cells":"32.7","Late spermatids":"8.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"FTO","Gene synonym":["ALKBH9","KIAA1752","MGC5149"],"Ensembl":"ENSG00000140718","Gene description":"FTO alpha-ketoglutarate dependent dioxygenase","Uniprot":["Q9C0B1"],"Chromosome":"16","Position":"53701692-54158512","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase","Transferase"],"Disease involvement":["Disease variant","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"168.0","Excitatory neurons":"222.9","Inhibitory neurons":"234.9","Microglial cells":"130.4","Oligodendrocyte precursor cells":"201.7","Oligodendrocytes":"266.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017123","HPA041086","HPA068695"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"540000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"CAB017123":null,"HPA041086":"AB_2677293","HPA068695":"AB_2732117"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"}},{"Gene":"FURIN","Gene synonym":["FUR","PACE","PCSK3","SPC1"],"Ensembl":"ENSG00000140564","Gene description":"Furin, paired basic amino acid cleaving enzyme","Uniprot":["P09958"],"Chromosome":"15","Position":"90868588-90883564","Protein class":["Enzymes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Heparin-binding","Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"305.6","salivary gland":"220.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"109.3","Hepatocytes":"114.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009499","HPA067869"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB009499":"AB_2105095","HPA067869":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.58e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"}},{"Gene":"FUT2","Gene synonym":["SE","Se2","SEC2","sej"],"Ensembl":"ENSG00000176920","Gene description":"Fucosyltransferase 2","Uniprot":["Q10981"],"Chromosome":"19","Position":"48695971-48705951","Protein class":["Blood group antigen proteins","Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Blood group antigen","Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"44.5","salivary gland":"66.2","stomach 1":"28.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"82.5","Gastric mucus-secreting cells":"69.8","Ionocytes":"147.3","Mucus glandular cells":"143.2","Proximal enterocytes":"190.7","Salivary duct cells":"112.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"5.5"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"19.4","Gastric cancer":"17.0"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Prostate - Urothelial cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"2.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014402"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA014402":"AB_1849194"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.83e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"}},{"Gene":"FUT3","Gene synonym":["CD174","LE"],"Ensembl":"ENSG00000171124","Gene description":"Fucosyltransferase 3 (Lewis blood group)","Uniprot":["P21217"],"Chromosome":"19","Position":"5842888-5851474","Protein class":["Blood group antigen proteins","Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Blood group antigen","Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"158.7","intestine":"72.3","retina":"79.3","salivary gland":"84.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"106.9","Ductal cells":"43.1","Intestinal goblet cells":"83.4","Ionocytes":"56.5","Paneth cells":"50.1","Proximal enterocytes":"80.8","Undifferentiated cells":"45.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"41.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"39.9"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Lung - Alveolar cells type 2","Prostate - Urothelial cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046966"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046966":"AB_2679879"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.86e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.22e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"FUT4","Gene synonym":["CD15","ELFT","FCT3A","FUC-TIV"],"Ensembl":"ENSG00000196371","Gene description":"Fucosyltransferase 4","Uniprot":["P22083"],"Chromosome":"11","Position":"94543840-94549898","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Inflammatory response"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"bone marrow":"100.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"20.4","Gastric mucus-secreting cells":"21.5","Intestinal goblet cells":"24.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"11.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"22.8","Leukemia":"24.6"},"RNA tissue cell type enrichment":["Pancreas - Ductal cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000014","CAB016129"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB000014":null,"CAB016129":"AB_626918"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.64e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"}},{"Gene":"FUT5","Gene synonym":["FUC-TV"],"Ensembl":"ENSG00000130383","Gene description":"Fucosyltransferase 5","Uniprot":["Q11128"],"Chromosome":"19","Position":"5865826-5870540","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046966"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 47: Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046966":"AB_2679879"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"FUT6","Gene synonym":["FCT3A","FLJ40754","FT1A","FucT-VI"],"Ensembl":"ENSG00000156413","Gene description":"Fucosyltransferase 6","Uniprot":["P51993"],"Chromosome":"19","Position":"5830408-5839722","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"79.4","kidney":"36.1","salivary gland":"45.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"43.7","Intestinal goblet cells":"72.3","Ionocytes":"40.8","Paneth cells":"33.3","Proximal enterocytes":"120.3","Proximal tubular cells":"57.7","Undifferentiated cells":"40.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"9.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bile duct cancer":"2.8","colorectal cancer":"7.9","Gastric cancer":"4.5"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Lung - Alveolar cells type 2","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043707","HPA046966"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"51000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA043707":"AB_2678628","HPA046966":"AB_2679879"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.12e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.17e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"}},{"Gene":"FUT7","Gene synonym":[],"Ensembl":"ENSG00000180549","Gene description":"Fucosyltransferase 7","Uniprot":["Q11130"],"Chromosome":"9","Position":"137030174-137032088","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"3.9","brain":"2.5","lymphoid tissue":"6.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"16.8","dendritic cells":"124.4","Langerhans cells":"34.5","NK-cells":"15.2","Schwann cells":"20.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"210.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"39","RNA cell line specific nTPM":{"Leukemia":"12.2","lymphoma":"11.3"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Lung - Neutrophil_2"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042780"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA042780":"AB_2678162"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"}},{"Gene":"FUT8","Gene synonym":[],"Ensembl":"ENSG00000033170","Gene description":"Fucosyltransferase 8","Uniprot":["Q9BYC5"],"Chromosome":"14","Position":"65410592-65744121","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"64.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"962.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"15.6","NK-cells":"14.8","T-cells":"10.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017129","HPA043410"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB017129":null,"HPA043410":"AB_2678467"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-3"}},{"Gene":"FUT9","Gene synonym":["Fuc-TIX"],"Ensembl":"ENSG00000172461","Gene description":"Fucosyltransferase 9","Uniprot":["Q9Y231"],"Chromosome":"6","Position":"96015974-96215612","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"18.9","stomach 1":"23.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"752.2","Excitatory neurons":"328.2","Inhibitory neurons":"232.4","Oligodendrocyte precursor cells":"161.7","Oligodendrocytes":"212.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070923"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Microtubules","Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Microtubules","Cytokinetic bridge","Cytosol"],"Antibody RRID":{"HPA070923":"AB_2686323"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"}},{"Gene":"FXYD1","Gene synonym":["PLM"],"Ensembl":"ENSG00000266964","Gene description":"FXYD domain containing ion transport regulator 1","Uniprot":["O00168"],"Chromosome":"19","Position":"35138824-35143109","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"1381.3","tongue":"838.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"93.3","Leydig cells":"59.5","Muller glia cells":"60.1","Schwann cells":"246.7","Skeletal myocytes":"78.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"8.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"11.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"11.0","T-cells":"6.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Colon - Enteric glia cells","Heart muscle - Cardiomyocytes","Kidney - Fibroblasts","Liver - Hepatocytes","Prostate - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026873"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA026873":"AB_1855471"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.91e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.59e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"}},{"Gene":"FXYD2","Gene synonym":["ATP1G1","HOMG2","MGC12372"],"Ensembl":"ENSG00000137731","Gene description":"FXYD domain containing ion transport regulator 2","Uniprot":["P54710"],"Chromosome":"11","Position":"117800844-117828698","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","FDA approved drug targets","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"kidney":"3645.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal tubular cells":"4344.3","Proximal tubular cells":"4188.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"renal cancer":"49.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory CD8 T-cell":"14.8","naive CD4 T-cell":"5.1","naive CD8 T-cell":"4.3","NK-cell":"9.6","plasmacytoid DC":"3.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"3.8","NK-cells":"9.6","T-cells":"14.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"248.4","Uterine cancer":"89.5"},"RNA tissue cell type enrichment":["Liver - Cholangiocyte","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"spinal cord":"27.7"},"Antibody":["HPA064218","HPA068838"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA064218":"AB_2685214","HPA068838":"AB_2686047"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.23e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"}},{"Gene":"FXYD3","Gene synonym":["MAT-8","PLML"],"Ensembl":"ENSG00000089356","Gene description":"FXYD domain containing ion transport regulator 3","Uniprot":["Q14802"],"Chromosome":"19","Position":"35115879-35124324","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Sodium\/potassium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"1800.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"621.8","Distal enterocytes":"2749.4","Intestinal goblet cells":"889.7","Paneth cells":"1317.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"1896.7"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Colon enterocytes","Lung - Alveolar cells type 1","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010856"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA010856":"AB_1078915"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.15e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-3"}},{"Gene":"FXYD4","Gene synonym":["CHIF"],"Ensembl":"ENSG00000150201","Gene description":"FXYD domain containing ion transport regulator 4","Uniprot":["P59646"],"Chromosome":"10","Position":"43371636-43376335","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"43","RNA tissue specific nTPM":{"kidney":"297.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"63","RNA single cell type specific nTPM":{"Collecting duct cells":"3924.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"renal cancer":"10.7","urothelial cancer":"20.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"lung cancer":"4.6","testis cancer":"10.2"},"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058421"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA058421":"AB_2683714"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"}},{"Gene":"FXYD5","Gene synonym":["OIT2"],"Ensembl":"ENSG00000089327","Gene description":"FXYD domain containing ion transport regulator 5","Uniprot":["Q96DB9"],"Chromosome":"19","Position":"35154730-35169881","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"548.0","granulocytes":"481.2","Hofbauer cells":"603.8","Langerhans cells":"536.3","monocytes":"525.9","T-cells":"473.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Colon - Endothelial cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010817"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA010817":"AB_1849214"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.71e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"}},{"Gene":"FXYD6","Gene synonym":[],"Ensembl":"ENSG00000137726","Gene description":"FXYD domain containing ion transport regulator 6","Uniprot":["Q9H0Q3"],"Chromosome":"11","Position":"117836976-117877486","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Schizophrenia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endothelial cells":"91.1","Leydig cells":"239.8","Muller glia cells":"122.0","Peritubular cells":"355.1","Sertoli cells":"270.9","Theca cells":"123.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"71.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"37.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"monocytes":"37.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"146.2"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Outer root sheath cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041334","HPA042284"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041334":"AB_10970752","HPA042284":"AB_2677931"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.87e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.97e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.38e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-4"}},{"Gene":"FXYD6-FXYD2","Gene synonym":[],"Ensembl":"ENSG00000255245","Gene description":"FXYD6-FXYD2 readthrough","Uniprot":[],"Chromosome":"11","Position":"117820163-117876667","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"7.5","salivary gland":"4.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Distal tubular cells":"143.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"1.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068838","HPA075209"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nuclear membrane","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA068838":"AB_2686047","HPA075209":"AB_2732285"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"FXYD7","Gene synonym":[],"Ensembl":"ENSG00000221946","Gene description":"FXYD domain containing ion transport regulator 7","Uniprot":["P58549"],"Chromosome":"19","Position":"35143250-35154302","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"273.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"41.5","Inhibitory neurons":"12.6","Microglial cells":"9.1","NK-cells":"13.2","T-cells":"19.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"4.2","ovarian cancer":"3.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"52.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"B-cells":"19.0","NK-cells":"52.1","T-cells":"23.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"6.0"},"RNA tissue cell type enrichment":["Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026916"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026916":"AB_1849217"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"FZD1","Gene synonym":["DKFZp564G072"],"Ensembl":"ENSG00000157240","Gene description":"Frizzled class receptor 1","Uniprot":["Q9UP38"],"Chromosome":"7","Position":"91264433-91271326","Protein class":["Cancer-related genes","G-protein coupled receptors","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Peritubular cells":"46.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"2.0","non-classical monocyte":"2.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"2.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Lung - Fibroblast_1","Skin - Eccrine sweat gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013008"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB013008":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.87e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"}},{"Gene":"FZD10","Gene synonym":["CD350"],"Ensembl":"ENSG00000111432","Gene description":"Frizzled class receptor 10","Uniprot":["Q9ULW2"],"Chromosome":"12","Position":"130162459-130165740","Protein class":["CD markers","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"16.7","skin 1":"9.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"8.2","Basal squamous epithelial cells":"15.2","Smooth muscle cells":"6.8","Squamous epithelial cells":"27.9","Suprabasal keratinocytes":"13.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"13.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Esophageal cancer":"3.0","head and neck cancer":"2.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"thalamus":"6.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014484","HPA014485"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA014484":"AB_1849132","HPA014485":"AB_1849134"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.05e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"FZD2","Gene synonym":[],"Ensembl":"ENSG00000180340","Gene description":"Frizzled class receptor 2","Uniprot":["Q14332"],"Chromosome":"17","Position":"44557484-44561262","Protein class":["Cancer-related genes","Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"10.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"20.2","Leydig cells":"41.6","Peritubular cells":"36.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.1","myeloid DC":"1.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"1.8","monocytes":"1.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057667"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA057667":"AB_2683497"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"}},{"Gene":"FZD3","Gene synonym":[],"Ensembl":"ENSG00000104290","Gene description":"Frizzled class receptor 3","Uniprot":["Q9NPG1"],"Chromosome":"8","Position":"28494205-28574267","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Neurogenesis","Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"14.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"153.7","Inhibitory neurons":"80.2","Rod photoreceptor cells":"92.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"9.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"9.3","T-cells":"2.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB024995","HPA042320"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB024995":null,"HPA042320":"AB_2677948"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.17e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.71e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-3"}},{"Gene":"FZD4","Gene synonym":["CD344","EVR1"],"Ensembl":"ENSG00000174804","Gene description":"Frizzled class receptor 4","Uniprot":["Q9ULV1"],"Chromosome":"11","Position":"86945679-86955395","Protein class":["CD markers","Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"120.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"83.3","Basal prostatic cells":"30.0","Endothelial cells":"65.0","Fibroblasts":"33.1","Skeletal myocytes":"28.7","Smooth muscle cells":"29.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"22.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Prostate - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042328","HPA074833"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA042328":"AB_10962494","HPA074833":"AB_2686716"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.60e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"}},{"Gene":"FZD5","Gene synonym":["C2orf31","DKFZP434E2135","HFZ5"],"Ensembl":"ENSG00000163251","Gene description":"Frizzled class receptor 5","Uniprot":["Q13467"],"Chromosome":"2","Position":"207762598-207769906","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"23.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"74.6","Alveolar cells type 2":"58.9","Distal enterocytes":"88.4","Hepatocytes":"49.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052361"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052361":"AB_2681799"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-3"}},{"Gene":"FZD6","Gene synonym":["Hfz6"],"Ensembl":"ENSG00000164930","Gene description":"Frizzled class receptor 6","Uniprot":["O60353"],"Chromosome":"8","Position":"103298433-103332866","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"96.4","Glandular and luminal cells":"70.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"NK-cell":"4.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"NK-cells":"4.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Heart muscle - Endothelial cells","Liver - Vascular Endothelial cells","Skeletal muscle - Endothelial cells","Stomach - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017991"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA017991":"AB_1849138"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"}},{"Gene":"FZD7","Gene synonym":["FzE3"],"Ensembl":"ENSG00000155760","Gene description":"Frizzled class receptor 7","Uniprot":["O75084"],"Chromosome":"2","Position":"202033855-202038441","Protein class":["G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"28.4","Breast myoepithelial cells":"29.4","Cardiomyocytes":"23.7","Mucus glandular cells":"28.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"30.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Skin - Outer root sheath cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059979","HPA069165","HPA076183"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059979":null,"HPA069165":"AB_2686096","HPA076183":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.71e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"}},{"Gene":"FZD8","Gene synonym":[],"Ensembl":"ENSG00000177283","Gene description":"Frizzled class receptor 8","Uniprot":["Q9H461"],"Chromosome":"10","Position":"35638247-35642296","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"39.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"42.3","Muller glia cells":"24.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045025","HPA071142"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA045025":"AB_10795888","HPA071142":"AB_2686349"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.21e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"}},{"Gene":"FZD9","Gene synonym":["CD349","FZD3"],"Ensembl":"ENSG00000188763","Gene description":"Frizzled class receptor 9","Uniprot":["O00144"],"Chromosome":"7","Position":"73433778-73436120","Protein class":["CD markers","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.6","skeletal muscle":"7.1","testis":"4.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"5.0","Late spermatids":"13.9","Muller glia cells":"5.5","Oligodendrocyte precursor cells":"14.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"melanoma":"6.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"}},{"Gene":"G0S2","Gene synonym":[],"Ensembl":"ENSG00000123689","Gene description":"G0\/G1 switch 2","Uniprot":["P27469"],"Chromosome":"1","Position":"209675412-209676390","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"796.7","bone marrow":"1345.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Langerhans cells":"6545.1","monocytes":"2147.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"44.5"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"60","RNA blood cell specific nTPM":{"neutrophil":"549.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"213","RNA blood lineage specific nTPM":{"granulocytes":"549.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"423.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skin - Adipocytes (Skin)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.72e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"}},{"Gene":"G3BP1","Gene synonym":["G3BP","HDH-VIII"],"Ensembl":"ENSG00000145907","Gene description":"G3BP stress granule assembly factor 1","Uniprot":["Q13283"],"Chromosome":"5","Position":"151771045-151812911","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction","Immunity","Innate immunity","Transport"],"Molecular function":["DNA-binding","Endonuclease","Helicase","Hydrolase","Nuclease","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004052","CAB037068"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB037068":"AB_1840864","HPA004052":"AB_1849348"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.33e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"}},{"Gene":"G6PC","Gene synonym":["G6PC1","G6PT","GSD1a"],"Ensembl":"ENSG00000131482","Gene description":"Glucose-6-phosphatase catalytic subunit","Uniprot":["P35575"],"Chromosome":"17","Position":"42900797-42914438","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Gluconeogenesis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"kidney":"75.1","liver":"286.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hepatocytes":"233.9","Proximal enterocytes":"170.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"72","RNA cancer specific FPKM":{"liver cancer":"151.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"liver cancer":"2.5"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052324"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052324":"AB_2681790"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.42e-5"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.79e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"}},{"Gene":"G6PC2","Gene synonym":["IGRP"],"Ensembl":"ENSG00000152254","Gene description":"Glucose-6-phosphatase catalytic subunit 2","Uniprot":["Q9NQR9"],"Chromosome":"2","Position":"168901291-168910000","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Gluconeogenesis"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"38","RNA tissue specific nTPM":{"pancreas":"30.9","retina":"12.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"23.6","Muller glia cells":"44.9","Pancreatic endocrine cells":"8.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"92","RNA cancer specific FPKM":{"pancreatic cancer":"9.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Beta cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"G6PC3","Gene synonym":["UGRP"],"Ensembl":"ENSG00000141349","Gene description":"Glucose-6-phosphatase catalytic subunit 3","Uniprot":["Q9BUM1"],"Chromosome":"17","Position":"44070735-44076344","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Gluconeogenesis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067052"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA067052":"AB_2685771"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.61e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"}},{"Gene":"G6PD","Gene synonym":["G6PD1"],"Ensembl":"ENSG00000160211","Gene description":"Glucose-6-phosphate dehydrogenase","Uniprot":["P11413"],"Chromosome":"X","Position":"154531391-154547572","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"105.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Sertoli cells":"127.2","Suprabasal keratinocytes":"114.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"412.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"412.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"900.6"},"RNA tissue cell type enrichment":["Lung - Macrophages","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000247","HPA000834"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2400000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA000247":"AB_1078978","HPA000834":"AB_1078977"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.45e-13"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"}},{"Gene":"GAA","Gene synonym":[],"Ensembl":"ENSG00000171298","Gene description":"Glucosidase alpha, acid","Uniprot":["P10253"],"Chromosome":"17","Position":"80101556-80119881","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","FDA approved drug targets","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"152.4","Extravillous trophoblasts":"164.1","Syncytiotrophoblasts":"160.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"66.6","eosinophil":"22.8","intermediate monocyte":"50.3","myeloid DC":"39.7","neutrophil":"27.0","non-classical monocyte":"68.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"39.7","granulocytes":"27.0","monocytes":"68.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Macrophages","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026970","HPA029126"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3800000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA026970":"AB_2672065","HPA029126":"AB_2672918"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.66e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"}},{"Gene":"GABBR1","Gene synonym":["GPRC3A","hGB1a"],"Ensembl":"ENSG00000204681","Gene description":"Gamma-aminobutyric acid type B receptor subunit 1","Uniprot":["Q9UBS5"],"Chromosome":"6","Position":"29555629-29633976","Protein class":["FDA approved drug targets","G-protein coupled receptors","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"145.8","Excitatory neurons":"57.9","Horizontal cells":"57.0","Inhibitory neurons":"66.5","Oligodendrocyte precursor cells":"69.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050483","HPA058459"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA050483":"AB_2681140","HPA058459":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.54e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.77e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"}},{"Gene":"GABBR2","Gene synonym":["GABABR2","GPR51","GPRC3B","HG20"],"Ensembl":"ENSG00000136928","Gene description":"Gamma-aminobutyric acid type B receptor subunit 2","Uniprot":["O75899"],"Chromosome":"9","Position":"98288109-98708935","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"90.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"381.0","Inhibitory neurons":"385.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"glioma":"7.2","thyroid cancer":"11.6","urothelial cancer":"3.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"8.5"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013820","HPA031684","CAB079065"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079065":null,"HPA013820":"AB_1849364","HPA031684":"AB_2673993"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"}},{"Gene":"GABRA1","Gene synonym":["EJM5"],"Ensembl":"ENSG00000022355","Gene description":"Gamma-aminobutyric acid type A receptor subunit alpha1","Uniprot":["P14867"],"Chromosome":"5","Position":"161847063-161899981","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"30","RNA tissue specific nTPM":{"brain":"55.1","retina":"17.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Bipolar cells":"172.3","Excitatory neurons":"217.5","Inhibitory neurons":"210.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"1.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"breast cancer":"2.5"},"RNA tissue cell type enrichment":["Stomach - Gastric enteroendocrine cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022502","HPA029363","HPA055746"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB022502":null,"HPA029363":null,"HPA055746":"AB_2682904"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GABRA2","Gene synonym":[],"Ensembl":"ENSG00000151834","Gene description":"Gamma-aminobutyric acid type A receptor subunit alpha2","Uniprot":["P47869"],"Chromosome":"4","Position":"46243548-46475230","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"31.5","epididymis":"8.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"412.2","Excitatory neurons":"154.0","Inhibitory neurons":"108.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"0.6","glioma":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"7.4"},"RNA tissue cell type enrichment":["Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029363","CAB079061"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB079061":null,"HPA029363":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"}},{"Gene":"GABRA3","Gene synonym":[],"Ensembl":"ENSG00000011677","Gene description":"Gamma-aminobutyric acid type A receptor subunit alpha3","Uniprot":["P34903"],"Chromosome":"X","Position":"152166234-152451315","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"15.5","choroid plexus":"16.3","retina":"9.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"69.3","Hofbauer cells":"13.9","Inhibitory neurons":"21.7","Oligodendrocyte precursor cells":"55.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"testis cancer":"16.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000839","HPA029363"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA000839":"AB_1078929","HPA029363":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"}},{"Gene":"GABRA4","Gene synonym":[],"Ensembl":"ENSG00000109158","Gene description":"Gamma-aminobutyric acid type A receptor subunit alpha4","Uniprot":["P48169"],"Chromosome":"4","Position":"46918900-46993581","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"7.5","heart muscle":"2.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"123.2","Inhibitory neurons":"156.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Colon enteroendocrine cells","Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GABRA5","Gene synonym":[],"Ensembl":"ENSG00000186297","Gene description":"Gamma-aminobutyric acid type A receptor subunit alpha5","Uniprot":["P31644"],"Chromosome":"15","Position":"26866911-26949208","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"111.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"27.1","Inhibitory neurons":"13.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.8"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"52.0","basal ganglia":"73.5","cerebral cortex":"98.6","hippocampal formation":"111.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"21.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029363","HPA077031","CAB079022"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB079022":null,"HPA029363":null,"HPA077031":"AB_2686825"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GABRA6","Gene synonym":[],"Ensembl":"ENSG00000145863","Gene description":"Gamma-aminobutyric acid type A receptor subunit alpha6","Uniprot":["Q16445"],"Chromosome":"5","Position":"161547063-161702593","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"114","RNA tissue specific nTPM":{"brain":"71.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"14","RNA brain regional specific nTPM":{"cerebellum":"71.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"40","RNA mouse brain regional specific nTPM":{"cerebellum":"1073.8"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"37","RNA pig brain regional specific nTPM":{"cerebellum":"262.3"},"Antibody":["CAB022462"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 26: NCI-H716 - Unknown function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022462":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GABRB1","Gene synonym":[],"Ensembl":"ENSG00000163288","Gene description":"Gamma-aminobutyric acid type A receptor subunit beta1","Uniprot":["P18505"],"Chromosome":"4","Position":"46993723-47426447","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"26.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Astrocytes":"897.4","Excitatory neurons":"434.1","Inhibitory neurons":"494.9","Oligodendrocyte precursor cells":"255.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-3"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GABRB2","Gene synonym":[],"Ensembl":"ENSG00000145864","Gene description":"Gamma-aminobutyric acid type A receptor subunit beta2","Uniprot":["P47870"],"Chromosome":"5","Position":"161288429-161549044","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"71.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Excitatory neurons":"562.3","Inhibitory neurons":"763.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"20","RNA cancer specific FPKM":{"thyroid cancer":"10.2"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"cerebellum":"63.2","cerebral cortex":"71.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"1.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001964","HPA067632"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001964":null,"HPA067632":"AB_2685874"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"}},{"Gene":"GABRB3","Gene synonym":[],"Ensembl":"ENSG00000166206","Gene description":"Gamma-aminobutyric acid type A receptor subunit beta3","Uniprot":["P28472"],"Chromosome":"15","Position":"26543546-26939539","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"29.5","retina":"31.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"132.0","Excitatory neurons":"512.1","Inhibitory neurons":"252.4","Oligodendrocyte precursor cells":"133.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"lung cancer":"12.1","Neuroblastoma":"46.3","prostate cancer":"18.7"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"}},{"Gene":"GABRD","Gene synonym":[],"Ensembl":"ENSG00000187730","Gene description":"Gamma-aminobutyric acid type A receptor subunit delta","Uniprot":["O14764"],"Chromosome":"1","Position":"2019329-2030758","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"49.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"14.6","Excitatory neurons":"29.6","Horizontal cells":"24.4","Inhibitory neurons":"36.7","Spermatogonia":"15.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"2.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044371"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA044371":"AB_2678916"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-8"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.12e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"}},{"Gene":"GABRE","Gene synonym":[],"Ensembl":"ENSG00000102287","Gene description":"Gamma-aminobutyric acid type A receptor subunit epsilon","Uniprot":["P78334"],"Chromosome":"X","Position":"151953124-151974680","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"52.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ionocytes":"28.4","Mucus glandular cells":"64.3","Syncytiotrophoblasts":"77.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"5.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hypothalamus":"18.4"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hypothalamus":"32.3"},"Antibody":["HPA045918"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045918":"AB_10961281"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.05e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"}},{"Gene":"GABRG1","Gene synonym":[],"Ensembl":"ENSG00000163285","Gene description":"Gamma-aminobutyric acid type A receptor subunit gamma1","Uniprot":["Q8N1C3"],"Chromosome":"4","Position":"46035769-46124054","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"44.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"131.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Myeloma":"1.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035622","HPA058102"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA035622":"AB_10603669","HPA058102":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-4"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GABRG2","Gene synonym":[],"Ensembl":"ENSG00000113327","Gene description":"Gamma-aminobutyric acid type A receptor subunit gamma2","Uniprot":["P18507"],"Chromosome":"5","Position":"162000057-162162977","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"20.0","retina":"10.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Bipolar cells":"112.0","Excitatory neurons":"236.8","Horizontal cells":"69.2","Inhibitory neurons":"163.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"4.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"1.6","granulocytes":"4.5","T-cells":"1.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"34.7"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB079060"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079060":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GABRG3","Gene synonym":[],"Ensembl":"ENSG00000182256","Gene description":"Gamma-aminobutyric acid type A receptor subunit gamma3","Uniprot":["Q99928"],"Chromosome":"15","Position":"26971181-27541984","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.6","retina":"27.1","testis":"9.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"437.5","Inhibitory neurons":"602.0","Late spermatids":"345.7","Muller glia cells":"161.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"1.5"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hypothalamus":"17.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skin - Eccrine sweat gland cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054010"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Plasma membrane","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Microtubules"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA054010":"AB_2682342"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"}},{"Gene":"GABRP","Gene synonym":[],"Ensembl":"ENSG00000094755","Gene description":"Gamma-aminobutyric acid type A receptor subunit pi","Uniprot":["O00591"],"Chromosome":"5","Position":"170763350-170814047","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"152.3","esophagus":"171.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"160.2","Club cells":"75.0","Endometrial ciliated cells":"133.9","Glandular and luminal cells":"487.1","Ionocytes":"130.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"breast cancer":"35.4","cervical cancer":"49.3","endometrial cancer":"16.8","pancreatic cancer":"41.9","stomach cancer":"25.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"11.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"11.8","monocytes":"5.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"418.8"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Prostate - Urothelial cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB014883"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB014883":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.37e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-3"}},{"Gene":"GABRQ","Gene synonym":[],"Ensembl":"ENSG00000268089","Gene description":"Gamma-aminobutyric acid type A receptor subunit theta","Uniprot":["Q9UN88"],"Chromosome":"X","Position":"152637895-152657542","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"72.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"4.5","Basal squamous epithelial cells":"4.5","Glandular and luminal cells":"3.5","Horizontal cells":"5.1","Squamous epithelial cells":"2.5","Suprabasal keratinocytes":"1.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"6.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"7.4","cervical cancer":"7.4"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"hypothalamus":"52.6"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"hypothalamus":"7.7","midbrain":"20.8","pons":"6.3"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"}},{"Gene":"GABRR1","Gene synonym":[],"Ensembl":"ENSG00000146276","Gene description":"Gamma-aminobutyric acid type A receptor subunit rho1","Uniprot":["P24046"],"Chromosome":"6","Position":"89177504-89231278","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"25","RNA tissue specific nTPM":{"retina":"24.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Bipolar cells":"53.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"3.5","thyroid cancer":"12.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"midbrain":"1.3"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"}},{"Gene":"GABRR2","Gene synonym":[],"Ensembl":"ENSG00000111886","Gene description":"Gamma-aminobutyric acid type A receptor subunit rho2","Uniprot":["P28476"],"Chromosome":"6","Position":"89254464-89315299","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"25","RNA tissue specific nTPM":{"retina":"31.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Bipolar cells":"153.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Myeloma":"4.7"},"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-3"}},{"Gene":"GABRR3","Gene synonym":[],"Ensembl":"ENSG00000183185","Gene description":"Gamma-aminobutyric acid type A receptor subunit rho3","Uniprot":["A8MPY1"],"Chromosome":"3","Position":"97986673-98035304","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"85","RNA tissue specific nTPM":{"retina":"14.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"17.0","Rod photoreceptor cells":"9.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"}},{"Gene":"GAL3ST4","Gene synonym":["FLJ12116"],"Ensembl":"ENSG00000197093","Gene description":"Galactose-3-O-sulfotransferase 4","Uniprot":["Q96RP7"],"Chromosome":"7","Position":"100159244-100168617","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"27.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"34.3","Macrophages":"11.7","Melanocytes":"13.9","Microglial cells":"22.8","Oligodendrocyte precursor cells":"23.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory CD4 T-cell":"4.5","naive CD4 T-cell":"15.0","naive CD8 T-cell":"4.6","plasmacytoid DC":"4.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"29","RNA blood lineage specific nTPM":{"dendritic cells":"4.7","T-cells":"15.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Heart muscle - Fibroblasts","Liver - Hepatic stellate cells","Skeletal muscle - Fibroblasts","Skin - Keratinocyte (other)","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038137","HPA038138"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"35000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA038137":"AB_10697239","HPA038138":"AB_2675854"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.44e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.57e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"}},{"Gene":"GALK2","Gene synonym":["GK2"],"Ensembl":"ENSG00000156958","Gene description":"Galactokinase 2","Uniprot":["Q01415"],"Chromosome":"15","Position":"49155656-49367869","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"90.9","Inhibitory neurons":"88.0","Oligodendrocytes":"103.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043564","HPA048267"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043564":"AB_2678557","HPA048267":"AB_2680335"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.31e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.88e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"}},{"Gene":"GALNT1","Gene synonym":["GalNAc-T1"],"Ensembl":"ENSG00000141429","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 1","Uniprot":["Q10472"],"Chromosome":"18","Position":"35581117-35711834","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Mucus glandular cells":"213.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012628"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2600000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012628":"AB_1849439"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"}},{"Gene":"GALNT11","Gene synonym":["GalNAc-T11"],"Ensembl":"ENSG00000178234","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 11","Uniprot":["Q8NCW6"],"Chromosome":"7","Position":"152025674-152122340","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Notch signaling pathway"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Heterotaxy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"408.0","kidney":"229.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"129.2","Inhibitory neurons":"127.6","Proximal tubular cells":"163.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"30.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039330"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039330":"AB_10795249"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.54e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"}},{"Gene":"GALNT13","Gene synonym":["GalNAc-T13","KIAA1918"],"Ensembl":"ENSG00000144278","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 13","Uniprot":["Q8IUC8"],"Chromosome":"2","Position":"153871922-154453979","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"30.1","retina":"9.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"211.6","Inhibitory neurons":"324.6","Oligodendrocyte precursor cells":"944.9","Oligodendrocytes":"375.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"9.9","Neuroblastoma":"11.5"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060775"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060775":"AB_2684358"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"}},{"Gene":"GALNT14","Gene synonym":["FLJ12691","GalNac-T10","GalNac-T14"],"Ensembl":"ENSG00000158089","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 14","Uniprot":["Q96FL9"],"Chromosome":"2","Position":"30910467-31155202","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"41.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"28.5","Inhibitory neurons":"77.2","Proximal enterocytes":"19.5","Proximal tubular cells":"34.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"renal cancer":"45.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"neutrophil":"8.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"8.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Kidney cancer":"120.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030138"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"27000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA030138":"AB_2673332"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-3"}},{"Gene":"GALNT16","Gene synonym":["GalNAc-T16","GALNTL1","KIAA1130"],"Ensembl":"ENSG00000100626","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 16","Uniprot":["Q8N428"],"Chromosome":"14","Position":"69259277-69357033","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"40.8","heart muscle":"45.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"16.1","Cardiomyocytes":"49.3","Early spermatids":"15.2","Excitatory neurons":"27.2","Fibroblasts":"20.9","Inhibitory neurons":"23.3","Smooth muscle cells":"14.3","Theca cells":"19.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"10.9","Sarcoma":"9.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Colon - Enteric glia cells","Heart muscle - Cardiomyocytes","Liver - Hepatic stellate cells","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059136","HPA075325"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA059136":"AB_2683919","HPA075325":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.23e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-5"}},{"Gene":"GALNT18","Gene synonym":["GalNAc-T18","GALNT15","GALNTL4","MGC71806"],"Ensembl":"ENSG00000110328","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 18","Uniprot":["Q6P9A2"],"Chromosome":"11","Position":"11270877-11622005","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"144.9","Excitatory neurons":"103.0","Inhibitory neurons":"152.4","Microglial cells":"77.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Stomach - Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012955","HPA070681"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"300000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA012955":"AB_1849460","HPA070681":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"}},{"Gene":"GALNT3","Gene synonym":["GalNAc-T3","HFTC","HHS"],"Ensembl":"ENSG00000115339","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 3","Uniprot":["Q14435"],"Chromosome":"2","Position":"165747588-165794659","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"stomach 1":"77.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"157.0","Intestinal goblet cells":"134.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"50.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Lung - Alveolar cells type 2","Stomach - Gastric mucous cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007613"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"440000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA007613":"AB_1078941"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.08e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.10e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"}},{"Gene":"GALNT7","Gene synonym":["GALNAC-T7"],"Ensembl":"ENSG00000109586","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 7","Uniprot":["Q86SF2"],"Chromosome":"4","Position":"173168811-173323967","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"168.2","Intestinal goblet cells":"117.1","Prostatic glandular cells":"234.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064243","HPA065317"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6200000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA064243":"AB_2685223","HPA065317":"AB_2685465"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.53e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.65e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"}},{"Gene":"GALNT9","Gene synonym":["GALNAC-T9"],"Ensembl":"ENSG00000182870","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 9","Uniprot":["Q9HCQ5"],"Chromosome":"12","Position":"132196372-132329589","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"22.5","kidney":"9.4","thyroid gland":"13.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"13.8","Excitatory neurons":"36.6","Horizontal cells":"17.3","Inhibitory neurons":"12.8","Thymic epithelial cells":"64.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"0.9","ovarian cancer":"0.5","renal cancer":"1.6","thyroid cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"5.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075016"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA075016":"AB_2686729"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"}},{"Gene":"GALNTL5","Gene synonym":["GalNAc-T5L","GALNT15"],"Ensembl":"ENSG00000106648","Gene description":"Polypeptide N-acetylgalactosaminyltransferase like 5","Uniprot":["Q7Z4T8"],"Chromosome":"7","Position":"151956379-152019929","Protein class":["Disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"testis":"10.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"98","RNA single cell type specific nTPM":{"Early spermatids":"342.7","Late spermatids":"584.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011140"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011140":"AB_1078944"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GALNTL6","Gene synonym":["GalNAc-T6L","GALNT17"],"Ensembl":"ENSG00000174473","Gene description":"Polypeptide N-acetylgalactosaminyltransferase like 6","Uniprot":["Q49A17"],"Chromosome":"4","Position":"171812254-173041559","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"7.8","lymphoid tissue":"2.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Excitatory neurons":"418.8","Inhibitory neurons":"1527.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"B-cells":"1.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"2.6"},"RNA tissue cell type enrichment":["Skin - Melanocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031019"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031019":"AB_10601653"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"}},{"Gene":"GALR1","Gene synonym":["GALNR","GALNR1"],"Ensembl":"ENSG00000166573","Gene description":"Galanin receptor 1","Uniprot":["P47211"],"Chromosome":"18","Position":"77249848-77277900","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"1.4","brain":"1.9","pituitary gland":"1.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"69.8","Oligodendrocyte precursor cells":"40.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"1.3"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"5.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074584"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA074584":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GALR2","Gene synonym":["GALNR2"],"Ensembl":"ENSG00000182687","Gene description":"Galanin receptor 2","Uniprot":["O43603"],"Chromosome":"17","Position":"76074781-76077537","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"7.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"6.2","granulocytes":"3.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"3.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044513"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044513":"AB_10962510"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"}},{"Gene":"GALR3","Gene synonym":[],"Ensembl":"ENSG00000128310","Gene description":"Galanin receptor 3","Uniprot":["O60755"],"Chromosome":"22","Position":"37823382-37825485","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"1.4","Late spermatids":"1.2","Respiratory ciliated cells":"1.2","Theca cells":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 20: Airway & Pancreas - Proteolysis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"}},{"Gene":"GAMT","Gene synonym":["PIG2","TP53I2"],"Ensembl":"ENSG00000130005","Gene description":"Guanidinoacetate N-methyltransferase","Uniprot":["Q14353"],"Chromosome":"19","Position":"1397026-1401570","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"615.1","skeletal muscle":"1234.9","tongue":"466.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"806.1","Proximal tubular cells":"387.5","Skeletal myocytes":"960.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"173.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Skin - Keratinocyte (other)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051806"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"420000","Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051806":"AB_2681619"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.57e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"GANAB","Gene synonym":["G2AN","GIIA","GluII","KIAA0088"],"Ensembl":"ENSG00000089597","Gene description":"Glucosidase II alpha subunit","Uniprot":["Q14697"],"Chromosome":"11","Position":"62624826-62646726","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Macrophages","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026874","HPA061426"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA026874":"AB_1849745","HPA061426":"AB_2684516"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.27e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.54e-4"}},{"Gene":"GAPT","Gene synonym":["C5orf29","FLJ33641"],"Ensembl":"ENSG00000175857","Gene description":"GRB2 binding adaptor protein, transmembrane","Uniprot":["Q8N292"],"Chromosome":"5","Position":"58491435-58497090","Protein class":["Predicted intracellular proteins"],"Biological process":["B-cell activation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"16.9","lymphoid tissue":"42.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"83.3","dendritic cells":"262.3","granulocytes":"64.1","Kupffer cells":"52.9","Macrophages":"40.4","monocytes":"99.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"eosinophil":"1000.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1000.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"22.4"},"RNA tissue cell type enrichment":["Skin - Mast cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011048","HPA011070"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"HPA011048":null,"HPA011070":"AB_1848887"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"}},{"Gene":"GAPVD1","Gene synonym":["DKFZP434C212","KIAA1521"],"Ensembl":"ENSG00000165219","Gene description":"GTPase activating protein and VPS9 domains 1","Uniprot":["Q14C86"],"Chromosome":"9","Position":"125261794-125367207","Protein class":["Predicted intracellular proteins"],"Biological process":["Endocytosis"],"Molecular function":["GTPase activation","Guanine-nucleotide releasing factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029386","HPA029387","HPA074882"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"46000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA029386":"AB_10599604","HPA029387":"AB_10600311","HPA074882":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"}},{"Gene":"GAS1","Gene synonym":[],"Ensembl":"ENSG00000180447","Gene description":"Growth arrest specific 1","Uniprot":["P54826"],"Chromosome":"9","Position":"86944362-86947506","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Growth arrest"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"105.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Fibroblasts":"146.5","Muller glia cells":"70.8","Thymic epithelial cells":"208.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"30.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"37.3","lymphoma":"28.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Adipose visceral - Mesothelial cells","Breast - Fibroblasts","Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB024164","HPA036085","HPA066902"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"27000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"CAB024164":"AB_2107950","HPA036085":"AB_2674932","HPA066902":"AB_2685746"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.96e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.26e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"}},{"Gene":"GASK1B","Gene synonym":["C4orf18","DKFZp434L142","ENED","FAM198B","FLJ38155"],"Ensembl":"ENSG00000164125","Gene description":"Golgi associated kinase 1B","Uniprot":["Q6UWH4"],"Chromosome":"4","Position":"158124474-158173318","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"206.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"80.7","Endothelial cells":"86.5","Granulosa cells":"127.0","Kupffer cells":"128.0","Macrophages":"76.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"34","RNA blood cell specific nTPM":{"classical monocyte":"50.6","intermediate monocyte":"28.8","myeloid DC":"15.1","non-classical monocyte":"14.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"41","RNA blood lineage specific nTPM":{"dendritic cells":"15.1","monocytes":"50.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"59.7"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007227"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA007227":"AB_1847689"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"}},{"Gene":"GBA2","Gene synonym":["AD035","DKFZp762K054","KIAA1605","SPG46"],"Ensembl":"ENSG00000070610","Gene description":"Glucosylceramidase beta 2","Uniprot":["Q9HCG7"],"Chromosome":"9","Position":"35736866-35749228","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Sphingolipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Glycosidase","Glycosyltransferase","Hydrolase","Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"99.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024026"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA024026":"AB_1849530"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.00e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.24e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.60e-4"}},{"Gene":"GBF1","Gene synonym":["ARF1GEF","KIAA0248"],"Ensembl":"ENSG00000107862","Gene description":"Golgi brefeldin A resistant guanine nucleotide exchange factor 1","Uniprot":["Q92538"],"Chromosome":"10","Position":"102245371-102382899","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Protein transport","Transport"],"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"28.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037759","HPA037760"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA037759":"AB_10671884","HPA037760":"AB_2675651"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"}},{"Gene":"GBP1","Gene synonym":[],"Ensembl":"ENSG00000117228","Gene description":"Guanylate binding protein 1","Uniprot":["P32455"],"Chromosome":"1","Position":"89051882-89065360","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Immunity"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"88.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"96.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - NK-cells (Lung)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015450"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015450":"AB_2109333"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.32e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.04e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.12e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"}},{"Gene":"GBP3","Gene synonym":["FLJ10961"],"Ensembl":"ENSG00000117226","Gene description":"Guanylate binding protein 3","Uniprot":["Q9H0R5"],"Chromosome":"1","Position":"89006679-89022894","Protein class":["Predicted intracellular proteins"],"Biological process":["Antiviral defense","Immunity"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"78.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"79.5","Proximal enterocytes":"114.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045657"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045657":"AB_10961631"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"}},{"Gene":"GCAT","Gene synonym":["KBL"],"Ensembl":"ENSG00000100116","Gene description":"Glycine C-acetyltransferase","Uniprot":["O75600"],"Chromosome":"22","Position":"37807905-37817176","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"140.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"69.1","Proximal tubular cells":"168.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020460","HPA063924"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear speckles","Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear speckles","Mitochondria"],"Antibody RRID":{"HPA020460":"AB_1849548","HPA063924":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"}},{"Gene":"GCGR","Gene synonym":["GGR"],"Ensembl":"ENSG00000215644","Gene description":"Glucagon receptor","Uniprot":["P47871"],"Chromosome":"17","Position":"81804132-81814008","Protein class":["FDA approved drug targets","G-protein coupled receptors","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Diabetes mellitus","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"kidney":"50.0","liver":"169.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hepatocytes":"56.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"10.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071228"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA071228":"AB_2686368"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"}},{"Gene":"GCK","Gene synonym":["HK4","MODY2"],"Ensembl":"ENSG00000106633","Gene description":"Glucokinase","Uniprot":["P35557"],"Chromosome":"7","Position":"44143213-44198170","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Allosteric enzyme","Kinase","Transferase"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"12.6","choroid plexus":"7.4","heart muscle":"8.8","liver":"21.5","pituitary gland":"23.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"4.4","Cardiomyocytes":"4.9","Muller glia cells":"3.1","Smooth muscle cells":"4.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"4.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"2.3","naive CD4 T-cell":"2.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"2.6"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Pancreas - Alpha cells","Pancreas - Beta cells","Prostate - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007034","HPA007093"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007034":"AB_1079050","HPA007093":"AB_1079051"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"}},{"Gene":"GCNT2","Gene synonym":["bA360O19.2","bA421M1.1","CCAT","GCNT5","IGNT","II","NACGT1","NAGCT1","ULG3"],"Ensembl":"ENSG00000111846","Gene description":"Glucosaminyl (N-acetyl) transferase 2 (I blood group)","Uniprot":["Q8N0V5"],"Chromosome":"6","Position":"10492223-10629368","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"13.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"66.1","Endometrial ciliated cells":"66.9","Glandular and luminal cells":"86.5","Melanocytes":"85.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"21.4"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Stomach - Parietal cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"61.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026776"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"750000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA026776":"AB_1849573"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"}},{"Gene":"GCNT3","Gene synonym":["C2\/4GnT","C2GnT-M","C2GnT2"],"Ensembl":"ENSG00000140297","Gene description":"Glucosaminyl (N-acetyl) transferase 3, mucin type","Uniprot":["O95395"],"Chromosome":"15","Position":"59594875-59640239","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"75.5","intestine":"142.9","salivary gland":"55.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"106.3","Distal enterocytes":"179.0","Ductal cells":"90.4","Glandular and luminal cells":"77.4","Proximal enterocytes":"87.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"16.4","pancreatic cancer":"29.8","stomach cancer":"20.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"63.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Stomach - Gastric mucous cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011154"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA011154":"AB_1078961"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.78e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.49e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"}},{"Gene":"GDAP1","Gene synonym":["CMT2K","CMT4","CMT4A"],"Ensembl":"ENSG00000104381","Gene description":"Ganglioside induced differentiation associated protein 1","Uniprot":["Q8TB36"],"Chromosome":"8","Position":"74320613-74518007","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"26.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"52.1","Cone photoreceptor cells":"93.1","Excitatory neurons":"74.6","Horizontal cells":"63.4","Inhibitory neurons":"65.7","Oligodendrocyte precursor cells":"65.0","Rod photoreceptor cells":"86.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014266","HPA024334"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA014266":"AB_1849581","HPA024334":"AB_1849583"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.82e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.68e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.54e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"}},{"Gene":"GDAP1L1","Gene synonym":[],"Ensembl":"ENSG00000124194","Gene description":"Ganglioside induced differentiation associated protein 1 like 1","Uniprot":["Q96MZ0"],"Chromosome":"20","Position":"44247099-44280947","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"30.7","pituitary gland":"17.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"9.2","Excitatory neurons":"20.6","Horizontal cells":"17.9","Inhibitory neurons":"22.9","Late spermatids":"31.4","Oligodendrocyte precursor cells":"9.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"glioma":"6.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"Neuroblastoma":"119.3"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054182","HPA063265"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA054182":null,"HPA063265":"AB_2684972"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"}},{"Gene":"GDPD1","Gene synonym":["FLJ37451","GDE4"],"Ensembl":"ENSG00000153982","Gene description":"Glycerophosphodiester phosphodiesterase domain containing 1","Uniprot":["Q8N9F7"],"Chromosome":"17","Position":"59220467-59275970","Protein class":["Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"33.2","Early spermatids":"60.9","Excitatory neurons":"64.2","Inhibitory neurons":"62.5","Oligodendrocyte precursor cells":"32.7","Oligodendrocytes":"34.4","Spermatocytes":"64.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.98e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-3"}},{"Gene":"GDPD2","Gene synonym":["FLJ20207","GDE3","OBDPF"],"Ensembl":"ENSG00000130055","Gene description":"Glycerophosphodiester phosphodiesterase domain containing 2","Uniprot":["Q9HCC8"],"Chromosome":"X","Position":"70423031-70433390","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"20.8","lymphoid tissue":"59.2","skin 1":"47.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"38.7","Distal enterocytes":"25.3","Muller glia cells":"28.5","Proximal enterocytes":"96.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"10.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"6.1"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"}},{"Gene":"GDPD3","Gene synonym":["MGC4171"],"Ensembl":"ENSG00000102886","Gene description":"Glycerophosphodiester phosphodiesterase domain containing 3","Uniprot":["Q7L5L3"],"Chromosome":"16","Position":"30104810-30113537","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"45.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"98.9","Extravillous trophoblasts":"85.5","Late spermatids":"411.5","Proximal tubular cells":"101.1","Suprabasal keratinocytes":"103.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"21.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"granulocytes":"2.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"22.8"},"RNA tissue cell type enrichment":["Breast - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041148","HPA041470"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytokinetic bridge","Cytosol"],"Antibody RRID":{"HPA041148":"AB_10794545","HPA041470":"AB_10795121"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.89e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-3"}},{"Gene":"GDPD4","Gene synonym":["GDE6"],"Ensembl":"ENSG00000178795","Gene description":"Glycerophosphodiester phosphodiesterase domain containing 4","Uniprot":["Q6W3E5"],"Chromosome":"11","Position":"77216558-77301687","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"1.5","testis":"3.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"10.0","Late spermatids":"18.6","Spermatocytes":"16.8","Spermatogonia":"4.0","Theca cells":"4.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"testis cancer":"1.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"1.0"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"23","RNA mouse brain regional specific nTPM":{"olfactory bulb":"2.3"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"}},{"Gene":"GDPD5","Gene synonym":["GDE2","PP1665"],"Ensembl":"ENSG00000158555","Gene description":"Glycerophosphodiester phosphodiesterase domain containing 5","Uniprot":["Q8WTR4"],"Chromosome":"11","Position":"75434640-75525941","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Neurogenesis"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"116.6","retina":"83.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"55.6","Cone photoreceptor cells":"113.7","Late spermatids":"170.3","Rod photoreceptor cells":"85.3","Syncytiotrophoblasts":"62.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"7.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"7.7","T-cells":"2.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Liver - Vascular Endothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065257","HPA066762","HPA069281"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA065257":"AB_2685447","HPA066762":"AB_2685715","HPA069281":"AB_2686107"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.59e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"}},{"Gene":"GET1","Gene synonym":["CHD5","WRB"],"Ensembl":"ENSG00000182093","Gene description":"Guided entry of tail-anchored proteins factor 1","Uniprot":["O00258"],"Chromosome":"21","Position":"39377698-39428528","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"176.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018527"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018527":"AB_1858860"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"}},{"Gene":"GET1-SH3BGR","Gene synonym":[],"Ensembl":"ENSG00000285815","Gene description":"GET1-SH3BGR readthrough","Uniprot":[],"Chromosome":"21","Position":"39380332-39515506","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"6.1","skeletal muscle":"4.8"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"4.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018527"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 69: BICR 18 - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018527":"AB_1858860"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GFM1","Gene synonym":["EFGM","EGF1","GFM","mtEF-G1"],"Ensembl":"ENSG00000168827","Gene description":"G elongation factor mitochondrial 1","Uniprot":["Q96RP9"],"Chromosome":"3","Position":"158644527-158695581","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Elongation factor"],"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034764","HPA034765","HPA061405"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA034764":"AB_2674320","HPA034765":"AB_10669849","HPA061405":"AB_2684505"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.20e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.16e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"}},{"Gene":"GFM2","Gene synonym":["EF-G2mt","EFG2","FLJ21661"],"Ensembl":"ENSG00000164347","Gene description":"GTP dependent ribosome recycling factor mitochondrial 2","Uniprot":["Q969S9"],"Chromosome":"5","Position":"74721206-74767147","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036863","HPA069871"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Midbody ring","Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Midbody ring"],"Antibody RRID":{"HPA036863":"AB_2675354","HPA069871":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"}},{"Gene":"GFPT1","Gene synonym":["GFA","GFAT","GFAT1","GFPT"],"Ensembl":"ENSG00000198380","Gene description":"Glutamine--fructose-6-phosphate transaminase 1","Uniprot":["Q06210"],"Chromosome":"2","Position":"69319780-69387250","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms"],"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"191.4","Intestinal goblet cells":"215.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047240"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"93000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA047240":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.13e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"}},{"Gene":"GFPT2","Gene synonym":["GFAT2"],"Ensembl":"ENSG00000131459","Gene description":"Glutamine-fructose-6-phosphate transaminase 2","Uniprot":["O94808"],"Chromosome":"5","Position":"180300698-180353336","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"112.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"29.5","Fibroblasts":"64.4","Thymic epithelial cells":"131.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"3.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"35","RNA blood lineage specific nTPM":{"T-cells":"3.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"40.9"},"RNA tissue cell type enrichment":["Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056892","HPA059910"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA056892":"AB_2683266","HPA059910":"AB_2684157"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.09e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.95e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.58e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.47e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"}},{"Gene":"GFRA1","Gene synonym":["GDNFR","GDNFRA","GFR-ALPHA-1","RET1L","RETL1","TRNR1"],"Ensembl":"ENSG00000151892","Gene description":"GDNF family receptor alpha 1","Uniprot":["P56159"],"Chromosome":"10","Position":"116056925-116273284","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"39.2","Breast glandular cells":"27.4","Fibroblasts":"49.5","Hepatocytes":"34.8","Oligodendrocyte precursor cells":"87.1","Schwann cells":"25.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"breast cancer":"40.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Kidney cancer":"60.9"},"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Prostate - Fibroblasts","Testis - Spermatogonia","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043829"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA043829":"AB_2678689"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"}},{"Gene":"GFRA2","Gene synonym":["GDNFRB","NTNRA","RETL2","TRNR2"],"Ensembl":"ENSG00000168546","Gene description":"GDNF family receptor alpha 2","Uniprot":["O00451"],"Chromosome":"8","Position":"21690398-21812357","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"9.4","thyroid gland":"8.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"267.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"6.2"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"5.0"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"9.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"2.5","monocytes":"9.2"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"56.4"},"RNA tissue cell type enrichment":["Liver - Kupffer cells","Skeletal muscle - Fibroblasts","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024704","CAB032791"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB032791":"AB_2110428","HPA024704":"AB_1849629"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-3"}},{"Gene":"GFRA3","Gene synonym":["GFRa-3"],"Ensembl":"ENSG00000146013","Gene description":"GDNF family receptor alpha 3","Uniprot":["O60609"],"Chromosome":"5","Position":"138252380-138274621","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"13.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Schwann cells":"119.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"11.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"cerebellum":"2.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Neuroblastoma":"14.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Enteric glia cells","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020731"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA020731":"AB_1849635"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"}},{"Gene":"GFRA4","Gene synonym":[],"Ensembl":"ENSG00000125861","Gene description":"GDNF family receptor alpha 4","Uniprot":["Q9GZZ7"],"Chromosome":"20","Position":"3659248-3663399","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"1.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1.5","Late spermatids":"3.0","Proximal tubular cells":"1.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"97","RNA cell line specific nTPM":{"thyroid cancer":"9.7"},"RNA tissue cell type enrichment":["Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GFRAL","Gene synonym":["bA360D14.1","C6orf144","GRAL","UNQ9356"],"Ensembl":"ENSG00000187871","Gene description":"GDNF family receptor alpha like","Uniprot":["Q6UXV0"],"Chromosome":"6","Position":"55327469-55402493","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047372"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Actin filaments","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Actin filaments","Focal adhesion sites"],"Antibody RRID":{"HPA047372":"AB_2680017"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GFY","Gene synonym":["Goofy"],"Ensembl":"ENSG00000261949","Gene description":"Golgi associated olfactory signaling regulator","Uniprot":["I3L273"],"Chromosome":"19","Position":"49423749-49428987","Protein class":["Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"1.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"13.0"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"13","RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.4"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"cerebellum":"6.6"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"}},{"Gene":"GGA1","Gene synonym":[],"Ensembl":"ENSG00000100083","Gene description":"Golgi associated, gamma adaptin ear containing, ARF binding protein 1","Uniprot":["Q9UJY5"],"Chromosome":"22","Position":"37608725-37633564","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"179.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"218.0","Spermatocytes":"178.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048280","HPA051016"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA048280":"AB_2680338","HPA051016":"AB_2681312"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.86e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"}},{"Gene":"GGA2","Gene synonym":["KIAA1080","VEAR"],"Ensembl":"ENSG00000103365","Gene description":"Golgi associated, gamma adaptin ear containing, ARF binding protein 2","Uniprot":["Q9UJY4"],"Chromosome":"16","Position":"23463542-23521995","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"158.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate basal glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034422","HPA043313","HPA063634"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB034422":"AB_2110748","HPA043313":"AB_2678421","HPA063634":"AB_2685067"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.71e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.70e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.68e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.15e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"}},{"Gene":"GGCX","Gene synonym":["VKCFD1"],"Ensembl":"ENSG00000115486","Gene description":"Gamma-glutamyl carboxylase","Uniprot":["P38435"],"Chromosome":"2","Position":"85544720-85561547","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"118.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"143.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018284"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018284":"AB_1849641"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.82e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"}},{"Gene":"GGT1","Gene synonym":["CD224","D22S672","D22S732","GGT"],"Ensembl":"ENSG00000100031","Gene description":"Gamma-glutamyltransferase 1","Uniprot":["P19440"],"Chromosome":"22","Position":"24594811-24629005","Protein class":["Candidate cardiovascular disease genes","CD markers","Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Glutathione biosynthesis","Lipid metabolism"],"Molecular function":["Acyltransferase","Hydrolase","Protease","Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"174.8","liver":"115.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal enterocytes":"20.0","Ductal cells":"54.8","Exocrine glandular cells":"40.9","Proximal enterocytes":"50.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"37.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"112.1"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Prostate - Prostate glandular cells","Stomach - Chief cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045635","HPA047534","HPA065444"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3600000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA045635":"AB_2679400","HPA047534":"AB_2680079","HPA065444":"AB_2685491"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.44e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"}},{"Gene":"GGT6","Gene synonym":["FLJ90165"],"Ensembl":"ENSG00000167741","Gene description":"Gamma-glutamyltransferase 6","Uniprot":["Q6P531"],"Chromosome":"17","Position":"4556927-4560818","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Glutathione biosynthesis"],"Molecular function":["Acyltransferase","Hydrolase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"53.8","intestine":"53.4","salivary gland":"55.8","skin 1":"56.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"186.6","Intestinal goblet cells":"68.9","Paneth cells":"116.3","Proximal enterocytes":"130.5","Suprabasal keratinocytes":"65.7","Undifferentiated cells":"70.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"14.7","colorectal cancer":"17.6"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Liver - Cholangiocyte"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023362","HPA027213"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"72000","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023362":"AB_1848955","HPA027213":"AB_10601326"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.35e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.42e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-3"}},{"Gene":"GGT7","Gene synonym":["D20S101","dJ18C9.2","GGTL3","GGTL5"],"Ensembl":"ENSG00000131067","Gene description":"Gamma-glutamyltransferase 7","Uniprot":["Q9UJ14"],"Chromosome":"20","Position":"34844720-34872856","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Glutathione biosynthesis"],"Molecular function":["Acyltransferase","Hydrolase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"60.0","Inhibitory neurons":"56.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013204","HPA013339"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1900000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA013204":"AB_1850347","HPA013339":"AB_2668816"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.26e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"}},{"Gene":"GGTA1","Gene synonym":["GGTA","GGTA1P","GLYT2"],"Ensembl":"ENSG00000204136","Gene description":"Glycoprotein alpha-galactosyltransferase 1 (inactive)","Uniprot":["Q4G0N0"],"Chromosome":"9","Position":"121444991-121499844","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"133.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"211.3","Langerhans cells":"274.5","Macrophages":"158.1","Serous glandular cells":"325.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"classical monocyte":"22.7","intermediate monocyte":"17.9","myeloid DC":"12.7","plasmacytoid DC":"27.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"27.5","monocytes":"22.7"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Prostate - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023262"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023262":"AB_1849651"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.33e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"}},{"Gene":"GGTLC2","Gene synonym":["GGTL4"],"Ensembl":"ENSG00000100121","Gene description":"Gamma-glutamyltransferase light chain 2","Uniprot":["Q14390"],"Chromosome":"22","Position":"22644475-22647903","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"testis":"18.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"16.7","Late spermatids":"19.8","Spermatocytes":"8.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045635","HPA047534"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045635":"AB_2679400","HPA047534":"AB_2680079"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GHITM","Gene synonym":["DERP2","HSPC282","My021","PTD010","TMBIM5"],"Ensembl":"ENSG00000165678","Gene description":"Growth hormone inducible transmembrane protein","Uniprot":["Q9H3K2"],"Chromosome":"10","Position":"84139509-84153568","Protein class":["Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1024.6","Early spermatids":"933.0","Late spermatids":"2621.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016464","HPA061664"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA016464":"AB_1849656","HPA061664":"AB_2684579"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.76e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.32e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"GHR","Gene synonym":["GHBP"],"Ensembl":"ENSG00000112964","Gene description":"Growth hormone receptor","Uniprot":["P10912"],"Chromosome":"5","Position":"42423439-42721878","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Dwarfism","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"84.7","liver":"213.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"52.2","Hepatocytes":"121.3","Inhibitory neurons":"113.4","Oligodendrocyte precursor cells":"173.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"breast cancer":"2.8","liver cancer":"7.6","prostate cancer":"8.1","renal cancer":"2.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"6.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045339","HPA057705"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol","Cytoplasmic bodies"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":2200000,"Blood concentration - Conc. blood MS [pg\/L]":"24000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol","Cytoplasmic bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA045339":"AB_2679294","HPA057705":"AB_2683507"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.73e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-6"}},{"Gene":"GHRHR","Gene synonym":[],"Ensembl":"ENSG00000106128","Gene description":"Growth hormone releasing hormone receptor","Uniprot":["Q02643"],"Chromosome":"7","Position":"30938669-30993254","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Dwarfism","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"351","RNA tissue specific nTPM":{"pituitary gland":"211.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"1.9","Spermatocytes":"1.6","Spermatogonia":"2.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"prostate cancer":"2.3"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 47: Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GHSR","Gene synonym":[],"Ensembl":"ENSG00000121853","Gene description":"Growth hormone secretagogue receptor","Uniprot":["Q92847"],"Chromosome":"3","Position":"172443291-172448456","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"15.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"hippocampal formation":"3.8","hypothalamus":"15.1","thalamus":"3.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"3.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GIGYF2","Gene synonym":["GYF2","KIAA0642","PARK11","PERQ2","PERQ3","TNRC15"],"Ensembl":"ENSG00000204120","Gene description":"GRB10 interacting GYF protein 2","Uniprot":["Q6Y7W6"],"Chromosome":"2","Position":"232697299-232860605","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"636.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050899","HPA054612","HPA059918","HPA065064"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA050899":"AB_2681267","HPA054612":"AB_2682542","HPA059918":"AB_2684160","HPA065064":"AB_2685417"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.97e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"}},{"Gene":"GIMAP1","Gene synonym":["HIMAP1","IAN2","IMAP1","IMAP38"],"Ensembl":"ENSG00000213203","Gene description":"GTPase, IMAP family member 1","Uniprot":["Q8WWP7"],"Chromosome":"7","Position":"150716606-150724284","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"24.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Adipocytes":"175.1","Endothelial cells":"132.5","Hofbauer cells":"44.1","Kupffer cells":"85.8","Macrophages":"56.2","monocytes":"99.4","NK-cells":"114.3","T-cells":"98.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"Leukemia":"3.6"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Prostate - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044887","HPA053441"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA044887":"AB_10960351","HPA053441":"AB_2682152"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.12e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"}},{"Gene":"GIMAP1-GIMAP5","Gene synonym":[],"Ensembl":"ENSG00000281887","Gene description":"GIMAP1-GIMAP5 readthrough","Uniprot":[],"Chromosome":"7","Position":"150716668-150743646","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"16.4"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"37.9","NK-cells":"69.5","T-cells":"101.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"1.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053441"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":null,"Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA053441":"AB_2682152"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GIMAP2","Gene synonym":["DKFZp586D0824","HIMAP2","IAN12","IMAP2"],"Ensembl":"ENSG00000106560","Gene description":"GTPase, IMAP family member 2","Uniprot":["Q9UG22"],"Chromosome":"7","Position":"150685697-150693641","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"78.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"50.3","Kupffer cells":"89.0","Macrophages":"43.2","monocytes":"76.1","NK-cells":"57.2","T-cells":"54.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"33.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013589","HPA014746"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Lipid droplets"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA013589":"AB_1849666","HPA014746":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"}},{"Gene":"GIMAP4","Gene synonym":["FLJ11110","HIMAP4","IAN1","IMAP4"],"Ensembl":"ENSG00000133574","Gene description":"GTPase, IMAP family member 4","Uniprot":["Q9NUV9"],"Chromosome":"7","Position":"150567369-150573953","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"127.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Adipocytes":"185.2","Endothelial cells":"224.0","Hofbauer cells":"119.8","Kupffer cells":"109.7","Macrophages":"128.3","monocytes":"122.4","NK-cells":"206.6","T-cells":"186.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"4.0","pancreatic cancer":"9.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019135","HPA019137","HPA027198"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019135":"AB_1849670","HPA019137":"AB_1849672","HPA027198":"AB_10602599"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.63e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"}},{"Gene":"GIMAP5","Gene synonym":["HIMAP3","IAN4L1","IAN5"],"Ensembl":"ENSG00000196329","Gene description":"GTPase, IMAP family member 5","Uniprot":["Q96F15"],"Chromosome":"7","Position":"150722253-150750033","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"106.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"19.9","Endothelial cells":"13.5","Macrophages":"5.7","NK-cells":"8.6","T-cells":"20.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"9.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Lung - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"}},{"Gene":"GINM1","Gene synonym":["C6orf72","dJ12G14.2"],"Ensembl":"ENSG00000055211","Gene description":"Glycoprotein integral membrane 1","Uniprot":["Q9NU53"],"Chromosome":"6","Position":"149566294-149591748","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"381.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017210","HPA041679"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"35000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoli fibrillar center","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA017210":"AB_1845743","HPA041679":"AB_2677611"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-3"}},{"Gene":"GINS3","Gene synonym":["FLJ13912","PSF3"],"Ensembl":"ENSG00000181938","Gene description":"GINS complex subunit 3","Uniprot":["Q9BRX5"],"Chromosome":"16","Position":"58295080-58406147","Protein class":["Predicted intracellular proteins"],"Biological process":["DNA replication"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"21.6","Schwann cells":"17.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041216","HPA048209"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA041216":"AB_10794989","HPA048209":"AB_2680314"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"}},{"Gene":"GIPR","Gene synonym":[],"Ensembl":"ENSG00000010310","Gene description":"Gastric inhibitory polypeptide receptor","Uniprot":["P48546"],"Chromosome":"19","Position":"45668221-45683722","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"stomach 1":"22.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"18.0","Gastric mucus-secreting cells":"34.6","Respiratory ciliated cells":"48.0","Rod photoreceptor cells":"18.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"pancreatic cancer":"4.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022710","HPA068054"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB022710":null,"HPA068054":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"}},{"Gene":"GJA1","Gene synonym":["CX43","GJAL","ODD","ODDD","ODOD","SDTY3"],"Ensembl":"ENSG00000152661","Gene description":"Gap junction protein alpha 1","Uniprot":["P17302"],"Chromosome":"6","Position":"121435595-121449727","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Cataract","Disease variant","Hypotrichosis","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"325.5","Astrocytes":"267.6","Cardiomyocytes":"222.8","Endometrial stromal cells":"211.0","Granulosa cells":"487.8","Suprabasal keratinocytes":"262.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"371.0","testis cancer":"453.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010753","HPA035097","HPA047551","HPA069245"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Vesicles","Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB010753":"AB_476857","HPA035097":"AB_2674460","HPA047551":"AB_2732540","HPA069245":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.99e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"}},{"Gene":"GJA10","Gene synonym":["CX62"],"Ensembl":"ENSG00000135355","Gene description":"Gap junction protein alpha 10","Uniprot":["Q969M2"],"Chromosome":"6","Position":"89894469-89921760","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Horizontal cells":"16.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"testis cancer":"1.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021145"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021145":"AB_2670600"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GJA3","Gene synonym":["CX46","CZP3"],"Ensembl":"ENSG00000121743","Gene description":"Gap junction protein alpha 3","Uniprot":["Q9Y6H8"],"Chromosome":"13","Position":"20138255-20161052","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"7.8","parathyroid gland":"4.0","placenta":"2.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"16.1","Sertoli cells":"5.5","Spermatogonia":"3.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"head and neck cancer":"1.3","melanoma":"3.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Podocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014821"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014821":"AB_2669097"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-3"}},{"Gene":"GJA4","Gene synonym":["CX37"],"Ensembl":"ENSG00000187513","Gene description":"Gap junction protein alpha 4","Uniprot":["P35212"],"Chromosome":"1","Position":"34792999-34795747","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"75.1","Endothelial cells":"64.4","Sertoli cells":"273.7","Smooth muscle cells":"221.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"2.0","ovarian cancer":"1.6"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Prostate - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047981"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047981":"AB_2680228"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.28e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-3"}},{"Gene":"GJA5","Gene synonym":["CX40"],"Ensembl":"ENSG00000265107","Gene description":"Gap junction protein alpha 5","Uniprot":["P36382"],"Chromosome":"1","Position":"147756199-147773362","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Atrial fibrillation","Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"36.7","placenta":"85.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Cytotrophoblasts":"147.3","Extravillous trophoblasts":"378.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"23.1","breast cancer":"16.0","testis cancer":"12.2"},"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Stomach - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013080","HPA071370"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013080":"AB_2533263","HPA071370":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"}},{"Gene":"GJA8","Gene synonym":["CAE","CAE1","CX50","CZP1"],"Ensembl":"ENSG00000121634","Gene description":"Gap junction protein alpha 8","Uniprot":["P48165"],"Chromosome":"1","Position":"147902795-147909269","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"46","RNA tissue specific nTPM":{"testis":"5.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"18.6","Spermatocytes":"33.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014715","HPA062940"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014715":"AB_2732411","HPA062940":"AB_2732693"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GJA9","Gene synonym":["CX58","CX59","GJA10"],"Ensembl":"ENSG00000131233","Gene description":"Gap junction protein alpha 9","Uniprot":["P57773"],"Chromosome":"1","Position":"38874069-38881587","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067850"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA067850":"AB_2685910"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"}},{"Gene":"GJB1","Gene synonym":["CMTX","CMTX1","CX32"],"Ensembl":"ENSG00000169562","Gene description":"Gap junction protein beta 1","Uniprot":["P08034"],"Chromosome":"X","Position":"71212811-71225516","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Dejerine-Sottas syndrome","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"100.9","liver":"335.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"130.9","Distal enterocytes":"63.9","Hepatocytes":"264.2","Paneth cells":"63.6","Proximal enterocytes":"119.6","Undifferentiated cells":"62.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"163.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"41.0","skin cancer":"81.9"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Prostate - Prostate glandular cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012994"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB012994":"AB_2533228"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.85e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"}},{"Gene":"GJB2","Gene synonym":["CX26","DFNA3","DFNB1","NSRD1"],"Ensembl":"ENSG00000165474","Gene description":"Gap junction protein beta 2","Uniprot":["P29033"],"Chromosome":"13","Position":"20187463-20192938","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Ectodermal dysplasia","Ichthyosis","Non-syndromic deafness","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"328.1","esophagus":"812.1","vagina":"519.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"232.7","Basal respiratory cells":"224.2","Basal squamous epithelial cells":"101.7","Squamous epithelial cells":"178.2","Suprabasal keratinocytes":"624.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"447.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"113.8"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013093","HPA014362"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB013093":"AB_2533903","HPA014362":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.45e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.25e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"}},{"Gene":"GJB3","Gene synonym":["CX31","DFNA2","EKV"],"Ensembl":"ENSG00000188910","Gene description":"Gap junction protein beta 3","Uniprot":["O75712"],"Chromosome":"1","Position":"34781214-34786369","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"esophagus":"77.8","skin 1":"145.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal keratinocytes":"100.0","Basal respiratory cells":"38.0","Basal squamous epithelial cells":"43.9","Squamous epithelial cells":"95.4","Suprabasal keratinocytes":"129.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"58.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"70.2"},"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074472"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Vesicles","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA074472":"AB_2686694"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.56e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.56e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"}},{"Gene":"GJB4","Gene synonym":["CX30.3"],"Ensembl":"ENSG00000189433","Gene description":"Gap junction protein beta 4","Uniprot":["Q9NTQ9"],"Chromosome":"1","Position":"34759740-34762327","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"43.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"4.0","Basal prostatic cells":"3.7","Basal respiratory cells":"12.9","Club cells":"6.6","Ionocytes":"6.7","Respiratory ciliated cells":"5.8","Suprabasal keratinocytes":"3.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"12.9","pancreatic cancer":"10.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055112","HPA073904"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA055112":"AB_2682699","HPA073904":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.48e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.24e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"}},{"Gene":"GJB5","Gene synonym":["CX31.1"],"Ensembl":"ENSG00000189280","Gene description":"Gap junction protein beta 5","Uniprot":["O95377"],"Chromosome":"1","Position":"34755047-34758512","Protein class":["Cancer-related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"esophagus":"101.0","skin 1":"95.1","vagina":"35.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"55.3","Basal respiratory cells":"47.6","Basal squamous epithelial cells":"28.9","Squamous epithelial cells":"69.6","Suprabasal keratinocytes":"107.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"36.7","head and neck cancer":"57.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"46.4","head and neck cancer":"56.3"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Skin - Keratinocyte (other)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038146"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038146":"AB_10697242"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.54e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-3"}},{"Gene":"GJB6","Gene synonym":["CX30","DFNA3","ED2","EDH","HED"],"Ensembl":"ENSG00000121742","Gene description":"Gap junction protein beta 6","Uniprot":["O95452"],"Chromosome":"13","Position":"20221962-20232365","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Ectodermal dysplasia","Non-syndromic deafness","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"95.6","esophagus":"195.4","vagina":"139.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"352.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"145.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"2.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"2.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"135.9","head and neck cancer":"52.1"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014846"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA014846":"AB_1847135"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"}},{"Gene":"GJB7","Gene synonym":["bA136M9.1","CX25"],"Ensembl":"ENSG00000164411","Gene description":"Gap junction protein beta 7","Uniprot":["Q6PEY0"],"Chromosome":"6","Position":"87282980-87329278","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"fallopian tube":"7.0","pituitary gland":"5.5","placenta":"2.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"10.8","Endometrial ciliated cells":"14.1","Extravillous trophoblasts":"4.7","Horizontal cells":"3.8","Ionocytes":"5.6","Respiratory ciliated cells":"6.7","Syncytiotrophoblasts":"9.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014392"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA014392":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"}},{"Gene":"GJC1","Gene synonym":["CX45","GJA7"],"Ensembl":"ENSG00000182963","Gene description":"Gap junction protein gamma 1","Uniprot":["P36383"],"Chromosome":"17","Position":"44798448-44830816","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"40.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"19.3","Sertoli cells":"74.6","Smooth muscle cells":"82.2","Spermatogonia":"25.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Prostate - Smooth muscle cells","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071788"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Cell Junctions","Cytosol"],"Antibody RRID":{"HPA071788":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.55e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.83e-4"}},{"Gene":"GJC2","Gene synonym":["CX46.6","CX47","GJA12","SPG44"],"Ensembl":"ENSG00000198835","Gene description":"Gap junction protein gamma 2","Uniprot":["Q5T442"],"Chromosome":"1","Position":"228149930-228159826","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Leukodystrophy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"51.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"19.0","Endothelial cells":"10.0","Oligodendrocytes":"25.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Kidney - Fibroblasts","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"white matter":"105.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069619"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA069619":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"}},{"Gene":"GJC3","Gene synonym":["CX30.2","GJE1"],"Ensembl":"ENSG00000176402","Gene description":"Gap junction protein gamma 3","Uniprot":["Q8NFK1"],"Chromosome":"7","Position":"99923266-99929620","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"8.7","pancreas":"11.1","salivary gland":"11.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"40.7","Breast myoepithelial cells":"28.6","Mucus glandular cells":"14.1","Prostatic glandular cells":"25.0","Schwann cells":"25.3","Serous glandular cells":"25.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"breast cancer":"3.8","melanoma":"3.0","prostate cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Breast glandular cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015024"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015024":"AB_1847132"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-3"}},{"Gene":"GJD2","Gene synonym":["CX36","GJA9"],"Ensembl":"ENSG00000159248","Gene description":"Gap junction protein delta 2","Uniprot":["Q9UKL4"],"Chromosome":"15","Position":"34751032-34754998","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"5.9","pituitary gland":"7.5","retina":"21.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"9.7","Cone photoreceptor cells":"50.0","Horizontal cells":"10.9","Pancreatic endocrine cells":"5.2","Rod photoreceptor cells":"18.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"32","RNA cancer specific FPKM":{"pancreatic cancer":"4.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"3.5","Sarcoma":"1.3","testis cancer":"2.1"},"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GJD3","Gene synonym":["Cx30.2","CX31.9","GJA11","GJC1"],"Ensembl":"ENSG00000183153","Gene description":"Gap junction protein delta 3","Uniprot":["Q8N144"],"Chromosome":"17","Position":"40360652-40364737","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"8.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"4.1","Basal prostatic cells":"2.1","Endometrial stromal cells":"2.3","Endothelial cells":"3.8","Glandular and luminal cells":"1.5","Theca cells":"1.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"1.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-4"}},{"Gene":"GJD4","Gene synonym":["CX40.1","FLJ90023"],"Ensembl":"ENSG00000177291","Gene description":"Gap junction protein delta 4","Uniprot":["Q96KN9"],"Chromosome":"10","Position":"35605341-35608935","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Paneth cells":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"1.7"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038266"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038266":"AB_10672741"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"}},{"Gene":"GJE1","Gene synonym":["CX23"],"Ensembl":"ENSG00000203733","Gene description":"Gap junction protein epsilon 1","Uniprot":["A6NN92"],"Chromosome":"6","Position":"142133090-142135151","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014916"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014916":"AB_1847134"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GK","Gene synonym":["GK1","GKD"],"Ensembl":"ENSG00000198814","Gene description":"Glycerol kinase","Uniprot":["P32189"],"Chromosome":"X","Position":"30653359-30731462","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Glycerol metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"90.7","kidney":"107.7","liver":"79.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"169.6","Macrophages":"92.8","monocytes":"206.6","Proximal enterocytes":"141.0","Proximal tubular cells":"132.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"neutrophil":"178.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"178.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060687"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060687":"AB_2684343"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.24e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-3"}},{"Gene":"GK2","Gene synonym":["GKP2","GKTA"],"Ensembl":"ENSG00000196475","Gene description":"Glycerol kinase 2","Uniprot":["Q14410"],"Chromosome":"4","Position":"79406361-79408228","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Glycerol metabolism","Spermatogenesis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"306","RNA tissue specific nTPM":{"testis":"89.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"60","RNA single cell type specific nTPM":{"Early spermatids":"619.6","Late spermatids":"223.7","Spermatocytes":"161.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060687"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060687":"AB_2684343"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GK3P","Gene synonym":["GKP3","GKTB"],"Ensembl":"ENSG00000229894","Gene description":"Glycerol kinase 3 pseudogene","Uniprot":["Q14409"],"Chromosome":"4","Position":"165277812-165279679","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Glycerol metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"testis":"13.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"92.8","Late spermatids":"32.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060687"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 69: BICR 18 - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060687":"AB_2684343"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-4"}},{"Gene":"GLA","Gene synonym":["GALA"],"Ensembl":"ENSG00000102393","Gene description":"Galactosidase alpha","Uniprot":["P06280"],"Chromosome":"X","Position":"101393273-101408012","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"462.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000237","HPA000966"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000237":"AB_1078968","HPA000966":"AB_1078969"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.62e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.16e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"}},{"Gene":"GLB1L3","Gene synonym":["FLJ90231"],"Ensembl":"ENSG00000166105","Gene description":"Galactosidase beta 1 like 3","Uniprot":["Q8NCI6"],"Chromosome":"11","Position":"134274245-134319564","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.0","prostate":"7.9","seminal vesicle":"4.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"12.4","Excitatory neurons":"38.9","Inhibitory neurons":"20.5","Oligodendrocyte precursor cells":"11.1","Spermatogonia":"8.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"5.0"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"4.0"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"gdT-cell":"1.2","memory CD4 T-cell":"3.1","memory CD8 T-cell":"1.9","naive CD4 T-cell":"2.4","naive CD8 T-cell":"1.9","T-reg":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"31","RNA blood lineage specific nTPM":{"T-cells":"3.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"2.9"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Pancreas - Alpha cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039916"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039916":"AB_2676746"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.97e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"}},{"Gene":"GLCCI1","Gene synonym":["FAM117C","GIG18","TSSN1"],"Ensembl":"ENSG00000106415","Gene description":"Glucocorticoid induced 1","Uniprot":["Q86VQ1"],"Chromosome":"7","Position":"7968796-8094272","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"33.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"190.6","Inhibitory neurons":"145.9","Microglial cells":"109.5","Oligodendrocyte precursor cells":"264.7","Plasma cells":"159.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"46.4"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001674","HPA005987"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA001674":"AB_1078971","HPA005987":"AB_1078970"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-3"}},{"Gene":"GLG1","Gene synonym":["CFR-1","ESL-1","MG-160"],"Ensembl":"ENSG00000090863","Gene description":"Golgi glycoprotein 1","Uniprot":["Q92896"],"Chromosome":"16","Position":"74447427-74607144","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Prostate - Fibroblasts","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010815"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA010815":"AB_2232486"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.56e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.97e-4"}},{"Gene":"GLIPR1","Gene synonym":["GliPR","RTVP1"],"Ensembl":"ENSG00000139278","Gene description":"GLI pathogenesis related 1","Uniprot":["P48060"],"Chromosome":"12","Position":"75480753-75503863","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"317.0","Extravillous trophoblasts":"476.9","Hofbauer cells":"311.6","Kupffer cells":"256.4","Langerhans cells":"492.0","Macrophages":"270.4","monocytes":"260.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011014"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"64000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011014":"AB_1849714"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.69e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"}},{"Gene":"GLIPR1L2","Gene synonym":["MGC39497"],"Ensembl":"ENSG00000180481","Gene description":"GLIPR1 like 2","Uniprot":["Q4G1C9"],"Chromosome":"12","Position":"75391089-75432688","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"testis":"46.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"346.5","Spermatocytes":"269.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039795","HPA039866"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA039795":"AB_10805595","HPA039866":"AB_10795235"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"}},{"Gene":"GLMP","Gene synonym":["C1orf85","MGC31963","NCU-G1"],"Ensembl":"ENSG00000198715","Gene description":"Glycosylated lysosomal membrane protein","Uniprot":["Q8WWB7"],"Chromosome":"1","Position":"156290089-156295689","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"179.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Fibroblasts","Lung - Macrophages","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029121"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029121":"AB_10600794"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.35e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-3"}},{"Gene":"GLOD4","Gene synonym":["C17orf25","CGI-150","HC71"],"Ensembl":"ENSG00000167699","Gene description":"Glyoxalase domain containing 4","Uniprot":["Q9HC38"],"Chromosome":"17","Position":"757097-783390","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Skin - Keratinocyte (other)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021623","HPA023246","HPA023248"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3500000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA021623":"AB_1844365","HPA023246":"AB_1844366","HPA023248":"AB_1844367"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.18e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"}},{"Gene":"GLP1R","Gene synonym":["GLP-1R"],"Ensembl":"ENSG00000112164","Gene description":"Glucagon like peptide 1 receptor","Uniprot":["P43220"],"Chromosome":"6","Position":"39048781-39091303","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.7","heart muscle":"2.7","pancreas":"7.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"1.1","Cardiomyocytes":"5.2","Exocrine glandular cells":"1.0","Inhibitory neurons":"1.2","Melanocytes":"1.7","Pancreatic endocrine cells":"1.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"1.8"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"20.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"}},{"Gene":"GLP2R","Gene synonym":[],"Ensembl":"ENSG00000065325","Gene description":"Glucagon like peptide 2 receptor","Uniprot":["O95838"],"Chromosome":"17","Position":"9822206-9892099","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"12.2","intestine":"13.5","urinary bladder":"11.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"27.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"1.1"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"basal ganglia":"3.0","cerebral cortex":"3.6","hippocampal formation":"3.2","white matter":"1.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"cervical cancer":"36.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Liver - Hepatic stellate cells","Lung - Fibroblast_2","Pancreas - Fibroblasts"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebral cortex":"2.1","hippocampal formation":"2.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022690","HPA049244"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB022690":null,"HPA049244":"AB_2680690"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-3"}},{"Gene":"GLRA1","Gene synonym":["STHE"],"Ensembl":"ENSG00000145888","Gene description":"Glycine receptor alpha 1","Uniprot":["P23415"],"Chromosome":"5","Position":"151822513-151924851","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"brain":"40.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"7.1","Excitatory neurons":"1.7","Inhibitory neurons":"4.9","Oligodendrocyte precursor cells":"1.4","Oligodendrocytes":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"hypothalamus":"9.4","midbrain":"15.1","pons and medulla":"26.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078885","CAB079042"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB079042":null,"HPA078885":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-3"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GLRA2","Gene synonym":["GLR"],"Ensembl":"ENSG00000101958","Gene description":"Glycine receptor alpha 2","Uniprot":["P23416"],"Chromosome":"X","Position":"14529298-14731812","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"28.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Inhibitory neurons":"72.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"0.6","glioma":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.2","Esophageal cancer":"1.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB070422","HPA078885"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 26: NCI-H716 - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB070422":"AB_11153055","HPA078885":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GLRA3","Gene synonym":[],"Ensembl":"ENSG00000145451","Gene description":"Glycine receptor alpha 3","Uniprot":["O75311"],"Chromosome":"4","Position":"174636920-174829247","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"10.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"14.4","Early spermatids":"17.7","Excitatory neurons":"51.8","Horizontal cells":"13.5","Inhibitory neurons":"10.9","Late spermatids":"26.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"1.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"1.6"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Colon enteroendocrine cells","Pancreas - Beta cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078885"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA078885":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"}},{"Gene":"GLRB","Gene synonym":[],"Ensembl":"ENSG00000109738","Gene description":"Glycine receptor beta","Uniprot":["P48167"],"Chromosome":"4","Position":"157076125-157172090","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.5","parathyroid gland":"33.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"166.3","Inhibitory neurons":"108.3","Oligodendrocyte precursor cells":"105.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052363"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052363":"AB_2681800"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.89e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"}},{"Gene":"GLT8D1","Gene synonym":["AD-017","FLJ14611"],"Ensembl":"ENSG00000016864","Gene description":"Glycosyltransferase 8 domain containing 1","Uniprot":["Q68CQ7"],"Chromosome":"3","Position":"52694486-52706032","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"135.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010588"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA010588":"AB_1078098"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"}},{"Gene":"GLT8D2","Gene synonym":["FLJ31494"],"Ensembl":"ENSG00000120820","Gene description":"Glycosyltransferase 8 domain containing 2","Uniprot":["Q9H1C3"],"Chromosome":"12","Position":"103988987-104064183","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"30.9","Early spermatids":"43.4","Fibroblasts":"49.8","Leydig cells":"56.8","Peritubular cells":"52.8","Thymic epithelial cells":"26.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Heart muscle - Fibroblasts","Liver - Hepatic stellate cells","Pancreas - Fibroblasts","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012740","HPA026904","HPA070791"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA012740":null,"HPA026904":"AB_1849731","HPA070791":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.37e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.92e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-3"}},{"Gene":"GMCL1","Gene synonym":["BTBD13","FLJ13057","GCL1","SPATA29"],"Ensembl":"ENSG00000087338","Gene description":"Germ cell-less 1, spermatogenesis associated","Uniprot":["Q96IK5"],"Chromosome":"2","Position":"69829660-69881384","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"192.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"93.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039579"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039579":"AB_10805480"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"}},{"Gene":"GMPPA","Gene synonym":[],"Ensembl":"ENSG00000144591","Gene description":"GDP-mannose pyrophosphorylase A","Uniprot":["Q96IJ6"],"Chromosome":"2","Position":"219498884-219506989","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"91.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035512","HPA035513"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"51000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA035512":"AB_2674660","HPA035513":"AB_10671934"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.24e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"}},{"Gene":"GMPPB","Gene synonym":["KIAA1851"],"Ensembl":"ENSG00000173540","Gene description":"GDP-mannose pyrophosphorylase B","Uniprot":["Q9Y5P6"],"Chromosome":"3","Position":"49716844-49723973","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"155.0","Syncytiotrophoblasts":"95.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014657"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014657":"AB_1849852"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.19e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.17e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"}},{"Gene":"GMPR2","Gene synonym":[],"Ensembl":"ENSG00000100938","Gene description":"Guanosine monophosphate reductase 2","Uniprot":["Q9P2T1"],"Chromosome":"14","Position":"24232422-24239242","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Purine metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000904","HPA067884","HPA068782"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA000904":"AB_1078998","HPA067884":"AB_2685916","HPA068782":"AB_2686032"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.21e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"}},{"Gene":"GMPS","Gene synonym":["GATD7"],"Ensembl":"ENSG00000163655","Gene description":"Guanine monophosphate synthase","Uniprot":["P49915"],"Chromosome":"3","Position":"155870650-155944020","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["GMP biosynthesis","Purine biosynthesis"],"Molecular function":["Ligase"],"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"100.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"273.7","Late spermatids":"195.8","Spermatocytes":"139.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046630"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046630":"AB_2679727"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.54e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.73e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"}},{"Gene":"GNAS","Gene synonym":["GNAS1","GNASXL","GPSA","NESP","NESP55","SCG6","SgVI"],"Ensembl":"ENSG00000087460","Gene description":"GNAS complex locus","Uniprot":["O95467","P63092","P84996","Q5JWF2"],"Chromosome":"20","Position":"58839718-58911192","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Transducer"],"Disease involvement":["Cancer-related genes","Cushing syndrome","Disease variant","Dwarfism","Obesity","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010337","HPA018122","HPA027478","HPA028386"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"CAB010337":"AB_631538","HPA018122":"AB_1849236","HPA027478":"AB_10599284","HPA028386":"AB_10601983"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.76e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"GNG14","Gene synonym":[],"Ensembl":"ENSG00000283980","Gene description":"G protein subunit gamma 14","Uniprot":["A0A1W2PPG7"],"Chromosome":"19","Position":"12687998-12688422","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"1.0","skin 1":"1.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"2.9"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GNPDA1","Gene synonym":["GNPDA","GNPI","GPI","HLN","KIAA0060"],"Ensembl":"ENSG00000113552","Gene description":"Glucosamine-6-phosphate deaminase 1","Uniprot":["P46926"],"Chromosome":"5","Position":"141991749-142013041","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Hydrolase","Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"116.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000499","HPA046891"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"930000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA000499":"AB_1079005","HPA046891":"AB_2679857"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.60e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"}},{"Gene":"GNPTAB","Gene synonym":["GNPTA","KIAA1208","MGC4170"],"Ensembl":"ENSG00000111670","Gene description":"N-acetylglucosamine-1-phosphate transferase subunits alpha and beta","Uniprot":["Q3T906"],"Chromosome":"12","Position":"101745499-101830959","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mucolipidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"176.3","NK-cells":"206.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014558","HPA042343"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA014558":"AB_2732409","HPA042343":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.48e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"}},{"Gene":"GNRHR","Gene synonym":["GRHR","LHRHR"],"Ensembl":"ENSG00000109163","Gene description":"Gonadotropin releasing hormone receptor","Uniprot":["P30968"],"Chromosome":"4","Position":"67737118-67754388","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","FDA approved drug targets","Hypogonadotropic hypogonadism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"pituitary gland":"5.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1.2","Granulosa cells":"1.8","Inhibitory neurons":"1.3","Suprabasal keratinocytes":"2.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013424"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013424":"AB_2668840"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"}},{"Gene":"GNS","Gene synonym":[],"Ensembl":"ENSG00000135677","Gene description":"Glucosamine (N-acetyl)-6-sulfatase","Uniprot":["P15586"],"Chromosome":"12","Position":"64713445-64759431","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"132.0","monocytes":"178.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"228.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013695","CAB026011","HPA048508"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"510000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026011":null,"HPA013695":"AB_1849741","HPA048508":"AB_2680423"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.76e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"}},{"Gene":"GOLGA4","Gene synonym":["GCP2","GOLG","golgin-240","p230"],"Ensembl":"ENSG00000144674","Gene description":"Golgin A4","Uniprot":["Q13439"],"Chromosome":"3","Position":"37243177-37366751","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1030.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035102","HPA040675"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA035102":"AB_10601472","HPA040675":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.62e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"}},{"Gene":"GOLGA5","Gene synonym":["golgin-84","GOLIM5","ret-II","rfg5"],"Ensembl":"ENSG00000066455","Gene description":"Golgin A5","Uniprot":["Q8TBA6"],"Chromosome":"14","Position":"92794305-92839947","Protein class":["Cancer-related genes","Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000992","HPA063876"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA000992":"AB_1079009","HPA063876":"AB_2685140"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"}},{"Gene":"GOLGB1","Gene synonym":["GCP","GCP372","giantin","GOLIM1"],"Ensembl":"ENSG00000173230","Gene description":"Golgin B1","Uniprot":["Q14789"],"Chromosome":"3","Position":"121663199-121749767","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011008","HPA011555"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA011008":"AB_1079011","HPA011555":"AB_1079010"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"}},{"Gene":"GOLM2","Gene synonym":["CASC4","DKFZp459F1927","H63"],"Ensembl":"ENSG00000166734","Gene description":"Golgi membrane protein 2","Uniprot":["Q6P4E1"],"Chromosome":"15","Position":"44288719-44415758","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Prostatic glandular cells":"206.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043015","HPA049488"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA043015":"AB_2678271","HPA049488":"AB_2680790"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"}},{"Gene":"GOLPH3L","Gene synonym":["GPP34R"],"Ensembl":"ENSG00000143457","Gene description":"Golgi phosphoprotein 3 like","Uniprot":["Q9H4A5"],"Chromosome":"1","Position":"150646230-150697154","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072016"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA072016":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"}},{"Gene":"GOLT1A","Gene synonym":["CGI-141","FLJ42654","GOT1","MGC62027","YMR292W"],"Ensembl":"ENSG00000174567","Gene description":"Golgi transport 1A","Uniprot":["Q6ZVE7"],"Chromosome":"1","Position":"204198163-204213988","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"liver":"190.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"129.0","Proximal enterocytes":"216.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"liver cancer":"80.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"35.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Lung - Alveolar cells type 2","Prostate - Prostate basal glandular cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"9.0"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.37e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.35e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.51e-4"}},{"Gene":"GOLT1B","Gene synonym":["CGI-141","GOT1","YMR292W"],"Ensembl":"ENSG00000111711","Gene description":"Golgi transport 1B","Uniprot":["Q9Y3E0"],"Chromosome":"12","Position":"21501781-21518408","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055909","HPA066383"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA055909":"AB_2682967","HPA066383":"AB_2685667"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.32e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.83e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"GOSR1","Gene synonym":["GOLIM2","GOS-28","GOS28","GS28","P28"],"Ensembl":"ENSG00000108587","Gene description":"Golgi SNAP receptor complex member 1","Uniprot":["O95249"],"Chromosome":"17","Position":"30477362-30527592","Protein class":["Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020590"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA020590":"AB_1850374"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.26e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"}},{"Gene":"GOSR2","Gene synonym":["Bos1","GS27"],"Ensembl":"ENSG00000108433","Gene description":"Golgi SNAP receptor complex member 2","Uniprot":["O14653"],"Chromosome":"17","Position":"46923075-46975524","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"267.8","Late spermatids":"1058.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017456","HPA054472"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB017456":"AB_10532285","HPA054472":"AB_2682499"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.80e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"}},{"Gene":"GOT1L1","Gene synonym":["MGC33309"],"Ensembl":"ENSG00000169154","Gene description":"Glutamic-oxaloacetic transaminase 1 like 1","Uniprot":["Q8NHS2"],"Chromosome":"8","Position":"37934281-37940124","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Aminotransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"25","RNA tissue specific nTPM":{"testis":"14.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"135.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028778"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA028778":"AB_10602138"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GP1BA","Gene synonym":["CD42b","GP1B","GPIbalpha"],"Ensembl":"ENSG00000185245","Gene description":"Glycoprotein Ib platelet subunit alpha","Uniprot":["P07359"],"Chromosome":"17","Position":"4932277-4935023","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Blood coagulation","Cell adhesion","Hemostasis"],"Molecular function":null,"Disease involvement":["Bernard Soulier syndrome","Disease variant","von Willebrand disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"4.9","lymphoid tissue":"14.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"3.1","Horizontal cells":"1.9","Langerhans cells":"2.7","Peritubular cells":"2.0","Rod photoreceptor cells":"1.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.8"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"2.1"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"basophil":"7.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"43","RNA blood lineage specific nTPM":{"granulocytes":"7.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002496","HPA013316"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002496":"AB_563748","HPA013316":"AB_1855459"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"}},{"Gene":"GP1BB","Gene synonym":["CD42c","GPIbbeta"],"Ensembl":"ENSG00000203618","Gene description":"Glycoprotein Ib platelet subunit beta","Uniprot":["P13224"],"Chromosome":"22","Position":"19723539-19724771","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Blood coagulation","Cell adhesion","Hemostasis"],"Molecular function":null,"Disease involvement":["Bernard Soulier syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"53.2","heart muscle":"27.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"74.0","neutrophil":"74.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"74.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4400000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GP2","Gene synonym":["ZAP75"],"Ensembl":"ENSG00000169347","Gene description":"Glycoprotein 2","Uniprot":["P55259"],"Chromosome":"16","Position":"20309574-20327808","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"966","RNA tissue specific nTPM":{"pancreas":"35381.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"24","RNA single cell type specific nTPM":{"Respiratory ciliated cells":"4453.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"pancreatic cancer":"320.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"breast cancer":"6.5"},"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015739","HPA016668"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"41000","Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 20: Airway & Pancreas - Proteolysis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015739":"AB_1849905","HPA016668":"AB_1849907"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GP5","Gene synonym":["CD42d"],"Ensembl":"ENSG00000178732","Gene description":"Glycoprotein V platelet","Uniprot":["P40197"],"Chromosome":"3","Position":"194394821-194398354","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins"],"Biological process":["Blood coagulation","Cell adhesion","Hemostasis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"1.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"testis cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"1.1"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072646"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA072646":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"}},{"Gene":"GP6","Gene synonym":["GPVI"],"Ensembl":"ENSG00000088053","Gene description":"Glycoprotein VI platelet","Uniprot":["Q9HCN6"],"Chromosome":"19","Position":"55013705-55038264","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"2.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"12.4","Excitatory neurons":"9.7","Inhibitory neurons":"10.0","Late spermatids":"10.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.2"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047611","HPA066482"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA047611":null,"HPA066482":"AB_2685674"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"}},{"Gene":"GP9","Gene synonym":["CD42a","GPIX"],"Ensembl":"ENSG00000169704","Gene description":"Glycoprotein IX platelet","Uniprot":["P14770"],"Chromosome":"3","Position":"129060779-129062406","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Blood coagulation","Cell adhesion","Hemostasis"],"Molecular function":null,"Disease involvement":["Bernard Soulier syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"5.1","lung":"3.2","lymphoid tissue":"8.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"8.0","Late spermatids":"20.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"29.5","neutrophil":"13.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"29.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"88","RNA cell line specific nTPM":{"Leukemia":"8.7"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063182"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2600000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA063182":"AB_2684956"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPA33","Gene synonym":["A33"],"Ensembl":"ENSG00000143167","Gene description":"Glycoprotein A33","Uniprot":["Q99795"],"Chromosome":"1","Position":"167052836-167166479","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"intestine":"215.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"508.9","Intestinal goblet cells":"232.0","Paneth cells":"368.6","Proximal enterocytes":"223.8","Undifferentiated cells":"85.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"colorectal cancer":"84.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"24.2","T-reg":"19.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"24.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"33.2","colorectal cancer":"96.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018858","CAB025943"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025943":null,"HPA018858":"AB_1849909"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"}},{"Gene":"GPAA1","Gene synonym":["GAA1","hGAA1"],"Ensembl":"ENSG00000197858","Gene description":"Glycosylphosphatidylinositol anchor attachment 1","Uniprot":["O43292"],"Chromosome":"8","Position":"144082590-144086216","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077224"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Centrosome","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":["Centrosome","Mitochondria"],"Antibody RRID":{"HPA077224":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"}},{"Gene":"GPAT3","Gene synonym":["AGPAT10","AGPAT9","HMFN0839","LPAAT-theta","MAG1","MGC11324"],"Ensembl":"ENSG00000138678","Gene description":"Glycerol-3-phosphate acyltransferase 3","Uniprot":["Q53EU6"],"Chromosome":"4","Position":"83535914-83605875","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"88.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Langerhans cells":"1090.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"182.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029414"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029414":"AB_10601562"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.71e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.21e-4"}},{"Gene":"GPAT4","Gene synonym":["AGPAT6","DKFZp586M1819","LPAAT-zeta","TSARG7"],"Ensembl":"ENSG00000158669","Gene description":"Glycerol-3-phosphate acyltransferase 4","Uniprot":["Q86UL3"],"Chromosome":"8","Position":"41577187-41625001","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016471"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016471":"AB_1844649"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.37e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.15e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.65e-4"}},{"Gene":"GPBAR1","Gene synonym":["BG37","GPCR","GPCR19","GPR131","M-BAR","MGC40597","TGR5"],"Ensembl":"ENSG00000179921","Gene description":"G protein-coupled bile acid receptor 1","Uniprot":["Q8TDU6"],"Chromosome":"2","Position":"218259496-218263861","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"31.9","breast":"17.8","gallbladder":"17.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"21.7","Enteroendocrine cells":"28.9","Hofbauer cells":"34.6","Kupffer cells":"32.5","Macrophages":"20.0","monocytes":"86.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"3.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"288.1","intermediate monocyte":"712.0","non-classical monocyte":"695.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"712.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"2.6","Neuroblastoma":"2.2","Rhabdoid":"5.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062890"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062890":"AB_2684896"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"}},{"Gene":"GPBP1","Gene synonym":["DKFZp761C169"],"Ensembl":"ENSG00000062194","Gene description":"GC-rich promoter binding protein 1","Uniprot":["Q86WP2"],"Chromosome":"5","Position":"57173948-57264679","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"733.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037773"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA037773":"AB_10671721"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.15e-5"}},{"Gene":"GPC1","Gene synonym":["glypican"],"Ensembl":"ENSG00000063660","Gene description":"Glypican 1","Uniprot":["P35052"],"Chromosome":"2","Position":"240435663-240468076","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"226.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"222.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"372.1"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Skin - Keratinocyte (other)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030571","HPA070449"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9500000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA030571":"AB_10602322","HPA070449":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.78e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.44e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"}},{"Gene":"GPC2","Gene synonym":["cerebroglycan","DKFZp547M109","FLJ38962"],"Ensembl":"ENSG00000213420","Gene description":"Glypican 2","Uniprot":["Q8N158"],"Chromosome":"7","Position":"100169606-100177381","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"5.2","skin 1":"5.7","testis":"11.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"13.6","Granulosa cells":"7.5","Late spermatids":"23.5","Oligodendrocyte precursor cells":"7.7","Spermatocytes":"12.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"46.7"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025423"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025423":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.94e-4"}},{"Gene":"GPC3","Gene synonym":["DGSX","OCI-5","SDYS","SGB","SGBS","SGBS1"],"Ensembl":"ENSG00000147257","Gene description":"Glypican 3","Uniprot":["P51654"],"Chromosome":"X","Position":"133535745-133985594","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Protease inhibitor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"placenta":"574.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"55.1","Extravillous trophoblasts":"70.5","Fibroblasts":"243.6","Muller glia cells":"71.1","Smooth muscle cells":"96.8","Syncytiotrophoblasts":"119.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"269.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"1.8","naive CD8 T-cell":"1.2"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"T-cells":"1.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Gastric cancer":"93.1","liver cancer":"297.4","Rhabdoid":"106.3","testis cancer":"233.8"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Kidney - Fibroblasts","Lung - Fibroblast_1","Pancreas - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006316"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"27000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA006316":"AB_1078994"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.83e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"}},{"Gene":"GPC4","Gene synonym":["K-glypican"],"Ensembl":"ENSG00000076716","Gene description":"Glypican 4","Uniprot":["O75487"],"Chromosome":"X","Position":"133300103-133415489","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"48.2","Astrocytes":"52.8","Extravillous trophoblasts":"41.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"testis cancer":"242.0"},"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030834","HPA030836"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA030834":null,"HPA030836":"AB_10601327"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.51e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"}},{"Gene":"GPC6","Gene synonym":[],"Ensembl":"ENSG00000183098","Gene description":"Glypican 6","Uniprot":["Q9Y625"],"Chromosome":"13","Position":"93226807-94408020","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"158.2","Excitatory neurons":"329.3","Inhibitory neurons":"484.6","Oligodendrocyte precursor cells":"662.3","Rod photoreceptor cells":"122.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"37.9","testis cancer":"39.5"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Colon - Fibroblasts","Pancreas - Fibroblasts","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013601","HPA017671"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"420000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA013601":null,"HPA017671":"AB_1849833"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-3"}},{"Gene":"GPER1","Gene synonym":["CEPR","CMKRL2","DRY12","FEG-1","GPCR-Br","GPER","GPR30","LERGU","LERGU2","LyGPR"],"Ensembl":"ENSG00000164850","Gene description":"G protein-coupled estrogen receptor 1","Uniprot":["Q99527"],"Chromosome":"7","Position":"1082208-1093815","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Cell cycle","Differentiation","Immunity","Inflammatory response","Innate immunity","Neurogenesis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"stomach 1":"45.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"8.6","Distal enterocytes":"9.3","Hepatocytes":"23.2","Kupffer cells":"13.6","Muller glia cells":"10.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"2.9","intermediate monocyte":"2.8","myeloid DC":"5.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"5.8","monocytes":"2.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"12.0"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Stomach - Chief cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016718","HPA027052"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm","Vesicles","Cytosol"],"Antibody RRID":{"HPA016718":null,"HPA027052":"AB_10612112"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"}},{"Gene":"GPHN","Gene synonym":["KIAA1385"],"Ensembl":"ENSG00000171723","Gene description":"Gephyrin","Uniprot":["Q9NQX3"],"Chromosome":"14","Position":"66507407-67181803","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Molybdenum cofactor biosynthesis"],"Molecular function":["Multifunctional enzyme","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"62.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"477.6","Excitatory neurons":"676.4","Inhibitory neurons":"846.3","Oligodendrocyte precursor cells":"551.6","Oligodendrocytes":"564.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003116","CAB004419","HPA024694"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6900","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004419":"AB_627670","HPA003116":"AB_1078963","HPA024694":"AB_1849616"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.61e-5"}},{"Gene":"GPI","Gene synonym":["AMF","NLK"],"Ensembl":"ENSG00000105220","Gene description":"Glucose-6-phosphate isomerase","Uniprot":["P06744"],"Chromosome":"19","Position":"34359480-34402413","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Gluconeogenesis","Glycolysis"],"Molecular function":["Cytokine","Growth factor","Isomerase"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"1163.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018655","HPA024305","CAB040563","HPA052171","CAB080077","CAB080078","CAB080085"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"86000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB018655":"AB_2112653","CAB040563":null,"CAB080077":null,"CAB080078":null,"CAB080085":null,"HPA024305":"AB_1849922","HPA052171":"AB_2681748"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"}},{"Gene":"GPIHBP1","Gene synonym":["GPI-HBP1","LOC338328"],"Ensembl":"ENSG00000277494","Gene description":"Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1","Uniprot":["Q8IV16"],"Chromosome":"8","Position":"143213218-143217170","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"90.7","breast":"54.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"332.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066302"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066302":"AB_2685654"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"}},{"Gene":"GPM6A","Gene synonym":["GPM6"],"Ensembl":"ENSG00000150625","Gene description":"Glycoprotein M6A","Uniprot":["P51674"],"Chromosome":"4","Position":"175632934-176002664","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Neurogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"577.8","choroid plexus":"249.3","retina":"147.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"3596.8","Excitatory neurons":"820.2","Inhibitory neurons":"566.9","Muller glia cells":"429.9","Oligodendrocyte precursor cells":"1284.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"107","RNA cancer specific FPKM":{"glioma":"110.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"memory B-cell":"34.8","naive B-cell":"16.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"B-cells":"34.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"14.0","lymphoma":"10.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Liver - Hepatic stellate cells","Lung - Alveolar cells type 1","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017338"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017338":"AB_1849933"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"}},{"Gene":"GPM6B","Gene synonym":["M6B","MGC17150","MGC54284"],"Ensembl":"ENSG00000046653","Gene description":"Glycoprotein M6B","Uniprot":["Q13491"],"Chromosome":"X","Position":"13770939-13938638","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis","Osteogenesis","Protein transport","Transport"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"743.2","choroid plexus":"180.7","retina":"207.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"613.6","Melanocytes":"674.0","Muller glia cells":"1537.2","Oligodendrocyte precursor cells":"390.9","Oligodendrocytes":"1393.9","Schwann cells":"1021.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"192.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"220","RNA blood cell specific nTPM":{"plasmacytoid DC":"77.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"268","RNA blood lineage specific nTPM":{"dendritic cells":"77.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Brain cancer":"39.0","Rhabdoid":"47.9","skin cancer":"66.6","testis cancer":"41.9"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Prostate - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002913"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002913":"AB_2263553"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.67e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"}},{"Gene":"GPNMB","Gene synonym":["HGFIN","NMB"],"Ensembl":"ENSG00000136235","Gene description":"Glycoprotein nmb","Uniprot":["Q14956"],"Chromosome":"7","Position":"23235967-23275108","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Amyloidosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"581.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"246.3","Cardiomyocytes":"254.1","Fibroblasts":"248.0","Hofbauer cells":"715.1","Macrophages":"348.0","Melanocytes":"947.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"354.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"2.1","intermediate monocyte":"3.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"monocytes":"3.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"skin cancer":"688.7"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Colon - Fibroblasts","Lung - Macrophages","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"9.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"33000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"}},{"Gene":"GPR1","Gene synonym":[],"Ensembl":"ENSG00000183671","Gene description":"G protein-coupled receptor 1","Uniprot":["P46091"],"Chromosome":"2","Position":"206175316-206218047","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"12.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"14.9","Granulosa cells":"40.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"2.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"10.6"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Colon - Fibroblasts","Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010525"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA010525":"AB_1078919"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-3"}},{"Gene":"GPR101","Gene synonym":[],"Ensembl":"ENSG00000165370","Gene description":"G protein-coupled receptor 101","Uniprot":["Q96P66"],"Chromosome":"X","Position":"137023929-137033995","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"143","RNA tissue specific nTPM":{"brain":"14.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Plasma cells":"2.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"12.4","cerebral cortex":"4.4","hypothalamus":"14.3","thalamus":"7.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"38.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001084"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001084":"AB_1078920"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR107","Gene synonym":["FLJ20998","KIAA1624","LUSTR1","RP11-88G17"],"Ensembl":"ENSG00000148358","Gene description":"G protein-coupled receptor 107","Uniprot":["Q5VW38"],"Chromosome":"9","Position":"130053426-130140169","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031704"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA031704":"AB_10601018"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.56e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.87e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"}},{"Gene":"GPR108","Gene synonym":["LUSTR2"],"Ensembl":"ENSG00000125734","Gene description":"G protein-coupled receptor 108","Uniprot":["Q9NPR9"],"Chromosome":"19","Position":"6729914-6737603","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041924","HPA041951","HPA063863"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA041924":"AB_10804122","HPA041951":"AB_10795385","HPA063863":"AB_2685135"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"}},{"Gene":"GPR119","Gene synonym":["GPCR2","hGPCR2"],"Ensembl":"ENSG00000147262","Gene description":"G protein-coupled receptor 119","Uniprot":["Q8TDV5"],"Chromosome":"X","Position":"130384345-130385660","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"pancreas":"2.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"pancreatic cancer":"2.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"thyroid cancer":"1.7"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.93e-4"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR12","Gene synonym":["GPCR21","PPP1R84"],"Ensembl":"ENSG00000132975","Gene description":"G protein-coupled receptor 12","Uniprot":["P47775"],"Chromosome":"13","Position":"26755200-26760786","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.3","retina":"8.4","skin 1":"5.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"9.4","Hofbauer cells":"14.9","Horizontal cells":"23.1","Inhibitory neurons":"15.4","Salivary duct cells":"8.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"breast cancer":"0.5","glioma":"0.8","ovarian cancer":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"lung cancer":"1.3","Rhabdoid":"2.3"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells (progenitors)","Skin - Eccrine sweat gland cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050972"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050972":"AB_2681295"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"}},{"Gene":"GPR132","Gene synonym":["G2A"],"Ensembl":"ENSG00000183484","Gene description":"G protein-coupled receptor 132","Uniprot":["Q9UNW8"],"Chromosome":"14","Position":"105049395-105065445","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Stress response"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"8.0","lymphoid tissue":"7.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"19.0","dendritic cells":"17.7","Langerhans cells":"60.6","Macrophages":"28.9","monocytes":"66.2","NK-cells":"19.1","T-cells":"21.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"5.3","lymphoma":"13.9","Myeloma":"7.7"},"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Prostate - T-cells","Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029694","HPA029695"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029694":"AB_10600213","HPA029695":"AB_10601984"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.21e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.44e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.71e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"}},{"Gene":"GPR135","Gene synonym":["HUMNPIIY20","PAFR"],"Ensembl":"ENSG00000181619","Gene description":"G protein-coupled receptor 135","Uniprot":["Q8IZ08"],"Chromosome":"14","Position":"59429022-59465342","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"137.6","Late spermatids":"224.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045337"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045337":"AB_10960528"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"}},{"Gene":"GPR137","Gene synonym":["C11orf4","GPR137A","TM7SF1L1"],"Ensembl":"ENSG00000173264","Gene description":"G protein-coupled receptor 137","Uniprot":["Q96N19"],"Chromosome":"11","Position":"64270062-64289500","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"203.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"181.0","Late spermatids":"548.2","Spermatocytes":"145.9","Syncytiotrophoblasts":"118.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"14.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062871"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA062871":"AB_2684889"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.34e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-1"}},{"Gene":"GPR137B","Gene synonym":["TM7SF1"],"Ensembl":"ENSG00000077585","Gene description":"G protein-coupled receptor 137B","Uniprot":["O60478"],"Chromosome":"1","Position":"236142505-236221865","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"135.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"154.5","Melanocytes":"104.5","Muller glia cells":"205.1","Rod photoreceptor cells":"160.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"17.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"17.6","monocytes":"7.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"65.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026422"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026422":"AB_1849338"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.63e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"GPR137C","Gene synonym":["DKFZp762F0713","TM7SF1L2"],"Ensembl":"ENSG00000180998","Gene description":"G protein-coupled receptor 137C","Uniprot":["Q8N3F9"],"Chromosome":"14","Position":"52552836-52637713","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"14.6","epididymis":"8.1","retina":"17.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"84.1","Inhibitory neurons":"122.2","Oligodendrocyte precursor cells":"97.2","Oligodendrocytes":"129.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"NK-cells":"1.5","T-cells":"1.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003640","HPA030763"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA003640":"AB_2667025","HPA030763":"AB_10602352"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"}},{"Gene":"GPR139","Gene synonym":["PGR3"],"Ensembl":"ENSG00000180269","Gene description":"G protein-coupled receptor 139","Uniprot":["Q6DWJ6"],"Chromosome":"16","Position":"20028239-20073890","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"4.9"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046596"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046596":"AB_2679713"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR141","Gene synonym":["PGR13"],"Ensembl":"ENSG00000187037","Gene description":"G protein-coupled receptor 141","Uniprot":["Q7Z602"],"Chromosome":"7","Position":"37683796-37833788","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"bone marrow":"27.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"11.5","Kupffer cells":"4.8","Langerhans cells":"9.0","Macrophages":"5.6","NK-cells":"13.9","Oligodendrocytes":"13.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"13.0","eosinophil":"9.7","gdT-cell":"5.2","memory CD8 T-cell":"5.1","myeloid DC":"6.6","naive CD8 T-cell":"3.4","neutrophil":"12.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"5.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"}},{"Gene":"GPR142","Gene synonym":["PGR2"],"Ensembl":"ENSG00000257008","Gene description":"G protein-coupled receptor 142","Uniprot":["Q7Z601"],"Chromosome":"17","Position":"74367407-74372622","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Enteroendocrine cells":"1.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"pancreatic cancer":"1.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Alpha cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031392"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA031392":"AB_10601935"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-3"}},{"Gene":"GPR143","Gene synonym":["OA1"],"Ensembl":"ENSG00000101850","Gene description":"G protein-coupled receptor 143","Uniprot":["P51810"],"Chromosome":"X","Position":"9725346-9786297","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Albinism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.2","choroid plexus":"14.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Melanocytes":"193.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"melanoma":"84.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"3.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"granulocytes":"3.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"skin cancer":"61.0"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Skin - Melanocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003648"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003648":"AB_2667028"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.73e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"}},{"Gene":"GPR146","Gene synonym":["PGR8"],"Ensembl":"ENSG00000164849","Gene description":"G protein-coupled receptor 146","Uniprot":["Q96CH1"],"Chromosome":"7","Position":"1044546-1059261","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"47.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"97.7","Endothelial cells":"54.2","Extravillous trophoblasts":"294.3","Syncytiotrophoblasts":"90.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"95.2","naive CD4 T-cell":"25.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"95.2","T-cells":"25.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"}},{"Gene":"GPR148","Gene synonym":["PGR6"],"Ensembl":"ENSG00000173302","Gene description":"G protein-coupled receptor 148","Uniprot":["Q8TDV2"],"Chromosome":"2","Position":"130729070-130730336","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046655","HPA060527"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA046655":null,"HPA060527":"AB_2684307"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-4"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR149","Gene synonym":["IEDA","PGR10","R35"],"Ensembl":"ENSG00000174948","Gene description":"G protein-coupled receptor 149","Uniprot":["Q86SP6"],"Chromosome":"3","Position":"154334943-154430190","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"6.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Inhibitory neurons":"47.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"prostate cancer":"1.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"15.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018020"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018020":"AB_1849334"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR15","Gene synonym":[],"Ensembl":"ENSG00000154165","Gene description":"G protein-coupled receptor 15","Uniprot":["P49685"],"Chromosome":"3","Position":"98531978-98534681","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"31.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"8.8","Plasma cells":"39.0","T-cells":"22.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"memory B-cell":"3.6","memory CD4 T-cell":"10.8","memory CD8 T-cell":"5.1","T-reg":"12.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"B-cells":"3.6","T-cells":"12.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"34.8"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Breast - Plasma cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013775"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013775":"AB_1849264"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"}},{"Gene":"GPR150","Gene synonym":["PGR11"],"Ensembl":"ENSG00000178015","Gene description":"G protein-coupled receptor 150","Uniprot":["Q8NGU9"],"Chromosome":"5","Position":"95620087-95622142","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.7","pancreas":"6.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"4.9","Extravillous trophoblasts":"5.9","Hofbauer cells":"2.9","Respiratory ciliated cells":"2.4","Sertoli cells":"2.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Macrophages","Stomach - Chief cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026635"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 20: Airway & Pancreas - Proteolysis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026635":"AB_1849266"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"}},{"Gene":"GPR151","Gene synonym":["GALR4","PGR7"],"Ensembl":"ENSG00000173250","Gene description":"G protein-coupled receptor 151","Uniprot":["Q8TDV0"],"Chromosome":"5","Position":"146513103-146516190","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"33","RNA tissue specific nTPM":{"brain":"8.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"3.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"40","RNA brain regional specific nTPM":{"midbrain":"8.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"19","RNA mouse brain regional specific nTPM":{"thalamus":"30.6"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"9","RNA pig brain regional specific nTPM":{"thalamus":"4.7"},"Antibody":["HPA065728"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA065728":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR152","Gene synonym":["PGR5"],"Ensembl":"ENSG00000175514","Gene description":"G protein-coupled receptor 152","Uniprot":["Q8TDT2"],"Chromosome":"11","Position":"67451301-67452729","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035078"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035078":"AB_10670286"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR153","Gene synonym":["PGR1"],"Ensembl":"ENSG00000158292","Gene description":"G protein-coupled receptor 153","Uniprot":["Q6NV75"],"Chromosome":"1","Position":"6247353-6261098","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"31.7","Horizontal cells":"47.4","Intestinal goblet cells":"59.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"35.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007159"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007159":"AB_1849268"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.07e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.75e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"GPR155","Gene synonym":["DEP.7","DEPDC3","FLJ31819","PGR22"],"Ensembl":"ENSG00000163328","Gene description":"G protein-coupled receptor 155","Uniprot":["Q7Z3F1"],"Chromosome":"2","Position":"174431571-174487094","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"83.4","stomach 1":"52.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"117.2","Inhibitory neurons":"127.9","Melanocytes":"268.2","Oligodendrocyte precursor cells":"124.7","Schwann cells":"245.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Kidney - Proximal tubular cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036159","HPA057384"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Nuclear bodies","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036159":"AB_10671835","HPA057384":"AB_2683424"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"}},{"Gene":"GPR156","Gene synonym":["GABABL","PGR28"],"Ensembl":"ENSG00000175697","Gene description":"G protein-coupled receptor 156","Uniprot":["Q8NFN8"],"Chromosome":"3","Position":"120164645-120285222","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"2.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"14.6","Early spermatids":"7.7","Late spermatids":"19.9","Oligodendrocyte precursor cells":"12.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028642","HPA028644"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA028642":"AB_10599711","HPA028644":"AB_10600441"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"}},{"Gene":"GPR157","Gene synonym":["FLJ12132"],"Ensembl":"ENSG00000180758","Gene description":"G protein-coupled receptor 157","Uniprot":["Q5UAW9"],"Chromosome":"1","Position":"9100305-9129102","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"59.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Langerhans cells":"318.8","Schwann cells":"119.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028697","HPA054948"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA028697":"AB_10601810","HPA054948":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"}},{"Gene":"GPR158","Gene synonym":["KIAA1136"],"Ensembl":"ENSG00000151025","Gene description":"G protein-coupled receptor 158","Uniprot":["Q5T848"],"Chromosome":"10","Position":"25174802-25602229","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"24.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"361.8","Inhibitory neurons":"294.5","Oligodendrocyte precursor cells":"401.9","Oligodendrocytes":"96.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"prostate cancer":"8.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Beta cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013185"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013185":"AB_2113957"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"}},{"Gene":"GPR160","Gene synonym":["GPCR1","GPCR150"],"Ensembl":"ENSG00000173890","Gene description":"G protein-coupled receptor 160","Uniprot":["Q9UJ42"],"Chromosome":"3","Position":"170037995-170085392","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"107.9","parathyroid gland":"216.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"186.3","Intestinal goblet cells":"128.4","Paneth cells":"133.8","Proximal enterocytes":"353.4","Proximal tubular cells":"139.8","Undifferentiated cells":"179.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"62.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Prostate glandular cells","Skeletal muscle - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006970"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA006970":"AB_1849275"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.21e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.93e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.61e-4"}},{"Gene":"GPR161","Gene synonym":["RE2"],"Ensembl":"ENSG00000143147","Gene description":"G protein-coupled receptor 161","Uniprot":["Q8N6U8"],"Chromosome":"1","Position":"168079543-168137667","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"41.5","smooth muscle":"27.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"18.6","Horizontal cells":"44.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Prostate - Smooth muscle cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015576","HPA072047"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA015576":"AB_1849283","HPA072047":"AB_2686484"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"}},{"Gene":"GPR162","Gene synonym":["A-2","GRCA"],"Ensembl":"ENSG00000250510","Gene description":"G protein-coupled receptor 162","Uniprot":["Q16538"],"Chromosome":"12","Position":"6821624-6829972","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"180.3","choroid plexus":"108.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"71.4","Excitatory neurons":"36.2","Horizontal cells":"73.1","Inhibitory neurons":"32.1","Muller glia cells":"46.8","Respiratory ciliated cells":"60.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"16.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"6.9","intermediate monocyte":"4.3","neutrophil":"17.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"17.4","monocytes":"6.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"17.4"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055135"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"HPA055135":"AB_2682710"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.29e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.37e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"}},{"Gene":"GPR17","Gene synonym":[],"Ensembl":"ENSG00000144230","Gene description":"G protein-coupled receptor 17","Uniprot":["Q13304"],"Chromosome":"2","Position":"127645864-127652639","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"19.8","intestine":"23.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"55.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"32","RNA cancer specific FPKM":{"glioma":"16.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"naive B-cell":"1.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"B-cells":"1.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029766"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029766":"AB_10612114"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"}},{"Gene":"GPR171","Gene synonym":["H963"],"Ensembl":"ENSG00000174946","Gene description":"G protein-coupled receptor 171","Uniprot":["O14626"],"Chromosome":"3","Position":"151197832-151203216","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"21.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"T-cells":"119.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"110.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"T-cells":"110.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"43","RNA cell line specific nTPM":{"Leukemia":"2.3","lymphoma":"7.6","Myeloma":"2.8"},"RNA tissue cell type enrichment":["Kidney - T-cells","Liver - T-cells","Prostate - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067323"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA067323":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"}},{"Gene":"GPR173","Gene synonym":["SREB3"],"Ensembl":"ENSG00000184194","Gene description":"G protein-coupled receptor 173","Uniprot":["Q9NS66"],"Chromosome":"X","Position":"53048789-53080615","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"18.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"42.1","Excitatory neurons":"19.4","Inhibitory neurons":"13.8","Oligodendrocyte precursor cells":"47.2","Oligodendrocytes":"39.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"8.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"3.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"31.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Colon - Enteric glia cells","Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003905"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA003905":"AB_1078922"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.88e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.47e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"}},{"Gene":"GPR174","Gene synonym":["FKSG79"],"Ensembl":"ENSG00000147138","Gene description":"G protein-coupled receptor 174","Uniprot":["Q9BXC1"],"Chromosome":"X","Position":"79144688-79175318","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"16.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"34.3","NK-cells":"37.3","T-cells":"75.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"10.7","lymphoma":"3.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Kidney - T-cells","Pancreas - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041025","HPA058306"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Centriolar satellite"],"Antibody RRID":{"HPA041025":"AB_10794260","HPA058306":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"}},{"Gene":"GPR176","Gene synonym":["Gm1012"],"Ensembl":"ENSG00000166073","Gene description":"G protein-coupled receptor 176","Uniprot":["Q14439"],"Chromosome":"15","Position":"39799008-39920266","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Biological rhythms"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"24.2","Excitatory neurons":"31.6","Inhibitory neurons":"55.6","Oligodendrocyte precursor cells":"39.0","Pancreatic endocrine cells":"18.9","Sertoli cells":"16.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039943","HPA039979"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039943":"AB_10697711","HPA039979":"AB_2676782"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.38e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.84e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"}},{"Gene":"GPR179","Gene synonym":["CSNB1E","GPR158L1"],"Ensembl":"ENSG00000277399","Gene description":"G protein-coupled receptor 179","Uniprot":[],"Chromosome":"17","Position":"38324571-38343956","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"retina":"13.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"29","RNA single cell type specific nTPM":{"Bipolar cells":"76.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017885"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017885":"AB_2279357"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-4"}},{"Gene":"GPR18","Gene synonym":[],"Ensembl":"ENSG00000125245","Gene description":"G protein-coupled receptor 18","Uniprot":["Q14330"],"Chromosome":"13","Position":"99254732-99261744","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"9.7","lymphoid tissue":"38.9","testis":"13.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"88.7","Late spermatids":"242.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"65.3","NK-cells":"52.9","T-cells":"41.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"Leukemia":"6.8","lymphoma":"21.4"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Breast - T-cells","Kidney - T-cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013873"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013873":"AB_1849285"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-3"}},{"Gene":"GPR180","Gene synonym":["ITR"],"Ensembl":"ENSG00000152749","Gene description":"G protein-coupled receptor 180","Uniprot":["Q86V85"],"Chromosome":"13","Position":"94601857-94634661","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"46.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047250"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA047250":"AB_2679998"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.18e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"}},{"Gene":"GPR182","Gene synonym":["ADMR","AM-R","G10D","hrhAMR"],"Ensembl":"ENSG00000166856","Gene description":"G protein-coupled receptor 182","Uniprot":["O15218"],"Chromosome":"12","Position":"56994492-56998447","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"17.0","testis":"6.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"197.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Sinusoid Endothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027037"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027037":"AB_1844622"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"}},{"Gene":"GPR183","Gene synonym":["EBI2"],"Ensembl":"ENSG00000169508","Gene description":"G protein-coupled receptor 183","Uniprot":["P32249"],"Chromosome":"13","Position":"99294539-99307399","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"112.7","lymphoid tissue":"84.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"4072.8","Langerhans cells":"3323.3","Macrophages":"815.4","Schwann cells":"967.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1050.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"13.7","lymphoma":"23.8","Myeloma":"6.6","Neuroblastoma":"7.0","thyroid cancer":"21.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033690","HPA075590"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033690":"AB_2114269","HPA075590":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.77e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-3"}},{"Gene":"GPR19","Gene synonym":[],"Ensembl":"ENSG00000183150","Gene description":"G protein-coupled receptor 19","Uniprot":["Q15760"],"Chromosome":"12","Position":"12660890-12696207","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.3","pituitary gland":"7.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"7.6","Early spermatids":"5.4","Excitatory neurons":"15.0","Inhibitory neurons":"15.2","Oligodendrocyte precursor cells":"14.9","Oligodendrocytes":"5.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"5.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"6.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"granulocytes":"2.9","T-cells":"6.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"28.5"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013955"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013955":"AB_1849287"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"}},{"Gene":"GPR20","Gene synonym":[],"Ensembl":"ENSG00000204882","Gene description":"G protein-coupled receptor 20","Uniprot":["Q99678"],"Chromosome":"8","Position":"141356470-141367286","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Sertoli cells":"27.6","Smooth muscle cells":"17.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"18","RNA blood cell specific nTPM":{"intermediate monocyte":"2.6","non-classical monocyte":"4.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"monocytes":"4.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Smooth muscle cells","Heart muscle - Smooth muscle cells","Testis - Endothelial cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071337"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA071337":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"}},{"Gene":"GPR21","Gene synonym":[],"Ensembl":"ENSG00000188394","Gene description":"G protein-coupled receptor 21","Uniprot":["Q99679"],"Chromosome":"9","Position":"123033667-123035665","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Smooth muscle cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"2.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041651"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041651":"AB_10794673"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-3"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR22","Gene synonym":[],"Ensembl":"ENSG00000172209","Gene description":"G protein-coupled receptor 22","Uniprot":["Q99680"],"Chromosome":"7","Position":"107470018-107475684","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.7","cervix":"2.1","heart muscle":"8.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"84.1","Excitatory neurons":"49.3","Inhibitory neurons":"50.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"17","RNA cell line specific nTPM":{"Neuroblastoma":"1.7"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"60.4"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"}},{"Gene":"GPR25","Gene synonym":[],"Ensembl":"ENSG00000170128","Gene description":"G protein-coupled receptor 25","Uniprot":["O00155"],"Chromosome":"1","Position":"200872981-200874178","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"stomach 1":"2.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Plasma cells":"11.5","T-cells":"6.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"1.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory CD4 T-cell":"27.5","T-reg":"44.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"57","RNA blood lineage specific nTPM":{"B-cells":"14.4","T-cells":"44.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"3.6"},"RNA tissue cell type enrichment":["Lung - T-cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-6"}},{"Gene":"GPR26","Gene synonym":[],"Ensembl":"ENSG00000154478","Gene description":"G protein-coupled receptor 26","Uniprot":["Q8NDV2"],"Chromosome":"10","Position":"123666355-123697399","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"brain":"7.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Excitatory neurons":"11.3","Horizontal cells":"8.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"breast cancer":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebral cortex":"62.7"},"Antibody":["HPA062736"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062736":"AB_2684855"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR27","Gene synonym":["SREB1"],"Ensembl":"ENSG00000170837","Gene description":"G protein-coupled receptor 27","Uniprot":["Q9NS67"],"Chromosome":"3","Position":"71753855-71756496","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"22.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"8.9","Breast myoepithelial cells":"7.1","Collecting duct cells":"9.8","Cone photoreceptor cells":"8.6","Glandular and luminal cells":"8.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"eosinophil":"2.8","neutrophil":"7.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"granulocytes":"7.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029395"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane","Actin filaments","Cytosol"],"Antibody RRID":{"HPA029395":"AB_10602907"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.63e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.21e-6"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"}},{"Gene":"GPR3","Gene synonym":["ACCA"],"Ensembl":"ENSG00000181773","Gene description":"G protein-coupled receptor 3","Uniprot":["P46089"],"Chromosome":"1","Position":"27392622-27395814","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"7.8","heart muscle":"5.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"5.5","Excitatory neurons":"2.5","Inhibitory neurons":"4.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Neutrophils","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006254"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB006254":"AB_425462"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"}},{"Gene":"GPR31","Gene synonym":["12-HETER","HETER1"],"Ensembl":"ENSG00000120436","Gene description":"G protein-coupled receptor 31","Uniprot":["O00270"],"Chromosome":"6","Position":"167155247-167157980","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"1.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Schwann cells":"5.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014014","HPA027108"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014014":"AB_1849292","HPA027108":"AB_10601474"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"}},{"Gene":"GPR32","Gene synonym":["RVDR1"],"Ensembl":"ENSG00000142511","Gene description":"G protein-coupled receptor 32","Uniprot":["O75388"],"Chromosome":"19","Position":"50770464-50771732","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"parathyroid gland":"58.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"29","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"6.4","Syncytiotrophoblasts":"2.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"32","RNA cell line specific nTPM":{"testis cancer":"3.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR33","Gene synonym":[],"Ensembl":"ENSG00000214943","Gene description":"G protein-coupled receptor 33","Uniprot":["Q49SQ1"],"Chromosome":"14","Position":"31482875-31488039","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"2.6"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"dendritic cells":"2.6"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR34","Gene synonym":[],"Ensembl":"ENSG00000171659","Gene description":"G protein-coupled receptor 34","Uniprot":["Q9UPC5"],"Chromosome":"X","Position":"41688973-41697275","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"42.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"51.9","Hofbauer cells":"222.8","Kupffer cells":"61.6","Macrophages":"136.6","Microglial cells":"52.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"26.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"basophil":"339.6","eosinophil":"117.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"24","RNA blood lineage specific nTPM":{"granulocytes":"339.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"1.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010668","CAB025490"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB025490":null,"HPA010668":"AB_1849294"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"}},{"Gene":"GPR35","Gene synonym":[],"Ensembl":"ENSG00000178623","Gene description":"G protein-coupled receptor 35","Uniprot":["Q9HC97"],"Chromosome":"2","Position":"240605430-240631259","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"41.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"65.6","Intestinal goblet cells":"27.4","Langerhans cells":"43.0","monocytes":"35.2","Paneth cells":"31.9","Proximal enterocytes":"91.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"20.7","pancreatic cancer":"6.9","stomach cancer":"9.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"classical monocyte":"36.3","eosinophil":"40.1","intermediate monocyte":"51.7","myeloid DC":"32.5","non-classical monocyte":"14.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"dendritic cells":"32.5","granulocytes":"40.1","monocytes":"51.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"54.5","Gastric cancer":"34.4"},"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.86e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.59e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"}},{"Gene":"GPR37","Gene synonym":["EDNRBL","hET(B)R-LP","PAELR"],"Ensembl":"ENSG00000170775","Gene description":"G protein-coupled receptor 37","Uniprot":["O15354"],"Chromosome":"7","Position":"124743885-124765792","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"109.5","retina":"39.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Muller glia cells":"605.4","Oligodendrocytes":"306.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"19.2","liver cancer":"5.7","melanoma":"10.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"8.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Liver - Hepatocytes","Pancreas - Ductal cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042903","HPA068009"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"900000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Nuclear membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042903":"AB_2678219","HPA068009":"AB_2685940"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.00e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.26e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-4"}},{"Gene":"GPR37L1","Gene synonym":["ETBR-LP-2"],"Ensembl":"ENSG00000170075","Gene description":"G protein-coupled receptor 37 like 1","Uniprot":["O60883"],"Chromosome":"1","Position":"202122917-202133592","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"76.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"88.9","Muller glia cells":"56.8","Oligodendrocyte precursor cells":"85.2","Oligodendrocytes":"19.3","Schwann cells":"24.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"57","RNA cancer specific FPKM":{"glioma":"36.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061629","HPA064454"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm","Cell Junctions"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"HPA061629":null,"HPA064454":"AB_2685268"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"}},{"Gene":"GPR39","Gene synonym":[],"Ensembl":"ENSG00000183840","Gene description":"G protein-coupled receptor 39","Uniprot":["O43194"],"Chromosome":"2","Position":"132416805-132646582","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"6.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"16.6","Astrocytes":"11.7","Early spermatids":"19.8","Late spermatids":"19.9","Oligodendrocyte precursor cells":"17.8","Spermatocytes":"26.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"plasmacytoid DC":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"dendritic cells":"1.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022111"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA022111":"AB_1849298"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-3"}},{"Gene":"GPR4","Gene synonym":[],"Ensembl":"ENSG00000177464","Gene description":"G protein-coupled receptor 4","Uniprot":["P46093"],"Chromosome":"19","Position":"45589764-45602212","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"40.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Adipocytes":"26.1","Endothelial cells":"33.3","Smooth muscle cells":"16.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"ovarian cancer":"2.4","prostate cancer":"1.3","Rhabdoid":"3.2","Sarcoma":"4.2","thyroid cancer":"4.0"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Lung - Endothelial cells","Prostate - Endothelial cells","Skin - Endothelial cells","Stomach - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014278"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014278":"AB_1849300"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.19e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.07e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"}},{"Gene":"GPR42","Gene synonym":["FFAR3L","GPR41L","GPR42P"],"Ensembl":"ENSG00000126251","Gene description":"G protein-coupled receptor 42","Uniprot":["O15529"],"Chromosome":"19","Position":"35370929-35372962","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"monocytes":"5.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044681"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044681":"AB_2679043"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-4"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR45","Gene synonym":["PSP24","PSP24A"],"Ensembl":"ENSG00000135973","Gene description":"G protein-coupled receptor 45","Uniprot":["Q9Y5Y3"],"Chromosome":"2","Position":"105241743-105243467","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"24","RNA single cell type specific nTPM":{"Early spermatids":"3.6","Late spermatids":"7.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"1.9"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055940"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055940":"AB_2682977"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"}},{"Gene":"GPR50","Gene synonym":["H9","Mel1c"],"Ensembl":"ENSG00000102195","Gene description":"G protein-coupled receptor 50","Uniprot":["Q13585"],"Chromosome":"X","Position":"151176584-151181465","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"pituitary gland":"17.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"1.4"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hypothalamus":"3.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Neuroblastoma":"32.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hypothalamus":"14.4","white matter":"5.0"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"10","RNA pig brain regional specific nTPM":{"hypothalamus":"4.8"},"Antibody":["HPA049862","HPA054678"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":null,"Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA049862":"AB_2680920","HPA054678":"AB_2682570"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR52","Gene synonym":[],"Ensembl":"ENSG00000203737","Gene description":"G protein-coupled receptor 52","Uniprot":["Q9Y2T5"],"Chromosome":"1","Position":"174447964-174449545","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"13.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7","Horizontal cells":"1.9","Rod photoreceptor cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"13.0","cerebellum":"3.2","cerebral cortex":"3.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"basal ganglia":"103.7"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"31.6"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-1"}},{"Gene":"GPR55","Gene synonym":[],"Ensembl":"ENSG00000135898","Gene description":"G protein-coupled receptor 55","Uniprot":["Q9Y2T6"],"Chromosome":"2","Position":"230907318-230961066","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.6","lymphoid tissue":"4.4","testis":"4.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1.8","dendritic cells":"2.2","Excitatory neurons":"2.3","Intestinal goblet cells":"2.4","Langerhans cells":"4.1","Plasma cells":"2.4","T-cells":"6.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"basal ganglia":"4.6"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"4.8","lymphoma":"4.8"},"RNA tissue cell type enrichment":["Prostate - T-cells","Skin - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-1"}},{"Gene":"GPR6","Gene synonym":[],"Ensembl":"ENSG00000146360","Gene description":"G protein-coupled receptor 6","Uniprot":["P46095"],"Chromosome":"6","Position":"109978256-109980718","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"24.5"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"24.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"basal ganglia":"91.1"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"29.7"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPR61","Gene synonym":["BALGR"],"Ensembl":"ENSG00000156097","Gene description":"G protein-coupled receptor 61","Uniprot":["Q9BZJ8"],"Chromosome":"1","Position":"109539872-109548406","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"3.2","pituitary gland":"3.5","retina":"3.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"17.3","Cone photoreceptor cells":"3.4","Excitatory neurons":"8.0","Horizontal cells":"9.0","Inhibitory neurons":"6.8","Schwann cells":"4.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007326","HPA026088"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007326":"AB_1849308","HPA026088":"AB_10602323"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"}},{"Gene":"GPR62","Gene synonym":[],"Ensembl":"ENSG00000180929","Gene description":"G protein-coupled receptor 62","Uniprot":["Q9BZJ7"],"Chromosome":"3","Position":"51955381-51957499","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"34.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Oligodendrocytes":"17.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"}},{"Gene":"GPR63","Gene synonym":["PSP24(beta)","PSP24B"],"Ensembl":"ENSG00000112218","Gene description":"G protein-coupled receptor 63","Uniprot":["Q9BZJ6"],"Chromosome":"6","Position":"96794125-96837477","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"33.3","Excitatory neurons":"45.5","Granulosa cells":"31.6","Inhibitory neurons":"19.8","Late spermatids":"30.8","Spermatocytes":"23.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"9.9"},"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039103"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039103":"AB_10672841"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"}},{"Gene":"GPR65","Gene synonym":["hTDAG8","TDAG8"],"Ensembl":"ENSG00000140030","Gene description":"G protein-coupled receptor 65","Uniprot":["Q8IYL9"],"Chromosome":"14","Position":"88005135-88014811","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"12.6","lymphoid tissue":"9.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"347.2","granulocytes":"401.5","NK-cells":"385.8","T-cells":"180.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"3.6","lymphoma":"7.2"},"RNA tissue cell type enrichment":["Skeletal muscle - Macrophages","Testis - Early spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072624","HPA077397"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA072624":null,"HPA077397":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.99e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-1"}},{"Gene":"GPR68","Gene synonym":["OGR1"],"Ensembl":"ENSG00000119714","Gene description":"G protein-coupled receptor 68","Uniprot":["Q15743"],"Chromosome":"14","Position":"91232532-91253925","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Amelogenesis imperfecta","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"12.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endothelial cells":"8.8","Hofbauer cells":"15.8","Langerhans cells":"33.9","NK-cells":"10.4","T-cells":"14.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"22.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"NK-cells":"20.2","T-cells":"22.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"9.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.06e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"}},{"Gene":"GPR75","Gene synonym":["WI-31133"],"Ensembl":"ENSG00000119737","Gene description":"G protein-coupled receptor 75","Uniprot":["O95800"],"Chromosome":"2","Position":"53852912-53859967","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7","Gastric mucus-secreting cells":"1.2","Glandular and luminal cells":"1.4","Mucus glandular cells":"2.2","Salivary duct cells":"1.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"4.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"}},{"Gene":"GPR78","Gene synonym":[],"Ensembl":"ENSG00000155269","Gene description":"G protein-coupled receptor 78","Uniprot":["Q96P69"],"Chromosome":"4","Position":"8558725-8619761","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"1.4","placenta":"3.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"20.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"1.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Bladder cancer":"5.8","testis cancer":"2.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013209"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013209":"AB_10601657"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"}},{"Gene":"GPR82","Gene synonym":[],"Ensembl":"ENSG00000171657","Gene description":"G protein-coupled receptor 82","Uniprot":["Q96P67"],"Chromosome":"X","Position":"41724181-41730130","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"2.7","lymphoid tissue":"6.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"15.6","Horizontal cells":"15.4","Kupffer cells":"21.1","Macrophages":"16.2","Rod photoreceptor cells":"16.5","T-cells":"13.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"eosinophil":"40.2","NK-cell":"10.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"40.2","NK-cells":"10.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Kupffer cells","Pancreas - Macrophages","Prostate - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035914"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035914":"AB_10670671"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"}},{"Gene":"GPR83","Gene synonym":["GPR72"],"Ensembl":"ENSG00000123901","Gene description":"G protein-coupled receptor 83","Uniprot":["Q9NYM4"],"Chromosome":"11","Position":"94377316-94401419","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"11.5","thyroid gland":"3.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"3.3","Excitatory neurons":"2.5","Inhibitory neurons":"4.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"1.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"67.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-3"}},{"Gene":"GPR84","Gene synonym":["EX33"],"Ensembl":"ENSG00000139572","Gene description":"G protein-coupled receptor 84","Uniprot":["Q9NQS5"],"Chromosome":"12","Position":"54362445-54364487","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"22.8","urinary bladder":"15.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hofbauer cells":"28.6","Langerhans cells":"21.9","Macrophages":"24.3","monocytes":"18.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"23","RNA blood cell specific nTPM":{"basophil":"9.0","classical monocyte":"9.9","myeloid DC":"14.8","neutrophil":"6.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"62","RNA blood lineage specific nTPM":{"dendritic cells":"14.8","granulocytes":"9.0","monocytes":"9.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"18","RNA cell line specific nTPM":{"Leukemia":"4.3","lymphoma":"8.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027603"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027603":"AB_10612115"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"}},{"Gene":"GPR85","Gene synonym":["SREB2"],"Ensembl":"ENSG00000164604","Gene description":"G protein-coupled receptor 85","Uniprot":["P60893"],"Chromosome":"7","Position":"113078331-113087778","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"39.1","choroid plexus":"19.8","retina":"12.1","skeletal muscle":"31.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"80.8","Early spermatids":"285.9","Horizontal cells":"88.4","Microglial cells":"39.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"7.8"},"RNA tissue cell type enrichment":["Liver - Kupffer cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"}},{"Gene":"GPR87","Gene synonym":["GPR95"],"Ensembl":"ENSG00000138271","Gene description":"G protein-coupled receptor 87","Uniprot":["Q9BY21"],"Chromosome":"3","Position":"151294086-151316820","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"35.9","skin 1":"32.8","vagina":"23.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"49.6","Basal respiratory cells":"143.3","Basal squamous epithelial cells":"49.1","Cytotrophoblasts":"58.0","Ionocytes":"60.9","Squamous epithelial cells":"51.2","Suprabasal keratinocytes":"64.8","Syncytiotrophoblasts":"220.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"cervical cancer":"44.1","head and neck cancer":"40.1","lung cancer":"22.0","urothelial cancer":"23.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"68.8","head and neck cancer":"101.6"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066313"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Lipid droplets","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Lipid droplets","Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA066313":"AB_2685656"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.62e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"}},{"Gene":"GPR88","Gene synonym":[],"Ensembl":"ENSG00000181656","Gene description":"G protein-coupled receptor 88","Uniprot":["Q9GZN0"],"Chromosome":"1","Position":"100538139-100542021","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"93.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Horizontal cells":"15.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"12.0"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"basal ganglia":"93.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"10","RNA mouse brain regional specific nTPM":{"basal ganglia":"718.8"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"42","RNA pig brain regional specific nTPM":{"basal ganglia":"273.1"},"Antibody":["HPA007488"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007488":"AB_2667844"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"}},{"Gene":"GPR89A","Gene synonym":["UNQ192"],"Ensembl":"ENSG00000117262","Gene description":"G protein-coupled receptor 89A","Uniprot":["B7ZAQ6"],"Chromosome":"1","Position":"145607988-145670650","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Protein transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"41.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076096"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA076096":"AB_2686777"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"}},{"Gene":"GPR89B","Gene synonym":["GPR89","GPR89C","SH120"],"Ensembl":"ENSG00000188092","Gene description":"G protein-coupled receptor 89B","Uniprot":["P0CG08"],"Chromosome":"1","Position":"147928393-147993592","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Protein transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"31.7","Inhibitory neurons":"31.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076096"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA076096":"AB_2686777"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-4"}},{"Gene":"GPRC5A","Gene synonym":["PEIG-1","RAI3","RAIG1","TIG1"],"Ensembl":"ENSG00000013588","Gene description":"G protein-coupled receptor class C group 5 member A","Uniprot":["Q8NFJ5"],"Chromosome":"12","Position":"12891559-12917937","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"201.9","urinary bladder":"130.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"1868.9","Alveolar cells type 2":"560.9","Club cells":"437.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007928","HPA046526"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA007928":"AB_1849318","HPA046526":"AB_2679685"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.63e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.02e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"}},{"Gene":"GPRC5B","Gene synonym":["RAIG-2"],"Ensembl":"ENSG00000167191","Gene description":"G protein-coupled receptor class C group 5 member B","Uniprot":["Q9NZH0"],"Chromosome":"16","Position":"19856691-19886167","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"490.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"94.8","Late spermatids":"283.3","Oligodendrocytes":"161.4","Sertoli cells":"91.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"52.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"2.8"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"T-cells":"2.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Pancreas - Ductal cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015247"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Nucleoli"],"Antibody RRID":{"HPA015247":"AB_1849323"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.27e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.30e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-3"}},{"Gene":"GPRC5C","Gene synonym":["RAIG-3"],"Ensembl":"ENSG00000170412","Gene description":"G protein-coupled receptor class C group 5 member C","Uniprot":["Q9NQ84"],"Chromosome":"17","Position":"74424851-74451653","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"192.7","stomach 1":"230.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"141.3","Hepatocytes":"173.8","Ionocytes":"148.8","Paneth cells":"186.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"7.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"7.9","monocytes":"3.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"cerebellum":"42.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029776"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA029776":"AB_10602324"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"}},{"Gene":"GPRC5D","Gene synonym":[],"Ensembl":"ENSG00000111291","Gene description":"G protein-coupled receptor class C group 5 member D","Uniprot":["Q9NZD1"],"Chromosome":"12","Position":"12940775-12952147","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"skin 1":"47.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"5.5","Gastric mucus-secreting cells":"4.2","Late spermatids":"6.6","Plasma cells":"16.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"memory B-cell":"21.9","naive B-cell":"7.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"B-cells":"21.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"Myeloma":"108.0"},"RNA tissue cell type enrichment":["Breast - Plasma cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071909"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA071909":"AB_2686470"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.09e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"}},{"Gene":"GPRC6A","Gene synonym":["bA86F4.3"],"Ensembl":"ENSG00000173612","Gene description":"G protein-coupled receptor class C group 6 member A","Uniprot":["Q5T6X5"],"Chromosome":"6","Position":"116792085-116829083","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Salivary duct cells":"21.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"renal cancer":"0.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Intercalated cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GPSM2","Gene synonym":["DFNB82","LGN","Pins"],"Ensembl":"ENSG00000121957","Gene description":"G protein signaling modulator 2","Uniprot":["P81274"],"Chromosome":"1","Position":"108875350-108934545","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","Mitosis","Transport"],"Molecular function":null,"Disease involvement":["Deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"46.9","tongue":"54.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"108.6","Oligodendrocyte precursor cells":"129.0","Oligodendrocytes":"120.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"eosinophil":"3.2","T-reg":"1.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"3.2","T-cells":"1.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007327","HPA008408","CAB018962"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB018962":null,"HPA007327":"AB_1849941","HPA008408":"AB_1849939"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.86e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.89e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"}},{"Gene":"GPX8","Gene synonym":["EPLA847","UNQ847"],"Ensembl":"ENSG00000164294","Gene description":"Glutathione peroxidase 8 (putative)","Uniprot":["Q8TED1"],"Chromosome":"5","Position":"55160167-55167297","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase","Peroxidase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"69.3","Extravillous trophoblasts":"258.2","Fibroblasts":"78.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Liver - Hepatic stellate cells","Lung - Fibroblast_2","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036720"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA036720":"AB_2675269"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.13e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.96e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"}},{"Gene":"GRAMD1A","Gene synonym":["FLJ90346","KIAA1533"],"Ensembl":"ENSG00000089351","Gene description":"GRAM domain containing 1A","Uniprot":["Q96CP6"],"Chromosome":"19","Position":"34994784-35026471","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Autophagy","Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"106.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008852","HPA012570"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA008852":"AB_1079203","HPA012570":"AB_2112577"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.95e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"}},{"Gene":"GRAMD1B","Gene synonym":["KIAA1201","LINC01059"],"Ensembl":"ENSG00000023171","Gene description":"GRAM domain containing 1B","Uniprot":["Q3KR37"],"Chromosome":"11","Position":"123358428-123627774","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"258.8","choroid plexus":"91.8","retina":"96.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"91.7","Cone photoreceptor cells":"110.3","dendritic cells":"105.9","Excitatory neurons":"119.1","Inhibitory neurons":"100.4","Oligodendrocyte precursor cells":"91.0","Rod photoreceptor cells":"111.9","Theca cells":"79.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"plasmacytoid DC":"7.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"7.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"40.9"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Cholangiocyte"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008557","HPA075204"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Endoplasmic reticulum","Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA008557":"AB_1079197","HPA075204":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.30e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"}},{"Gene":"GRAMD1C","Gene synonym":["DKFZp434C0328"],"Ensembl":"ENSG00000178075","Gene description":"GRAM domain containing 1C","Uniprot":["Q8IYS0"],"Chromosome":"3","Position":"113828182-113947174","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"176.2","Early spermatids":"106.8","Glandular and luminal cells":"57.6","Late spermatids":"79.9","Oligodendrocyte precursor cells":"78.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"memory B-cell":"2.7","naive B-cell":"2.9","neutrophil":"2.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"B-cells":"2.9","granulocytes":"2.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012316"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA012316":"AB_1849949"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.22e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"}},{"Gene":"GRAMD2A","Gene synonym":["GRAMD2"],"Ensembl":"ENSG00000175318","Gene description":"GRAM domain containing 2A","Uniprot":["Q8IUY3"],"Chromosome":"15","Position":"72159806-72197787","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"35.9","placenta":"48.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"106.3","Syncytiotrophoblasts":"126.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"14.4"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Prostate - Prostate basal glandular cells","Stomach - Gastric enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029435"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoli","Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA029435":"AB_10601811"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.01e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"}},{"Gene":"GRAMD2B","Gene synonym":["FLJ21313","GRAMD3","NS3TP2"],"Ensembl":"ENSG00000155324","Gene description":"GRAM domain containing 2B","Uniprot":["Q96HH9"],"Chromosome":"5","Position":"126360132-126496494","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"431.8","Glandular and luminal cells":"161.0","Oligodendrocyte precursor cells":"145.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"2.9","MAIT T-cell":"2.8","memory CD4 T-cell":"1.6","memory CD8 T-cell":"2.3","myeloid DC":"1.7","naive CD4 T-cell":"3.0","naive CD8 T-cell":"1.8","NK-cell":"1.1","plasmacytoid DC":"4.3","T-reg":"2.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"4.3","NK-cells":"1.1","T-cells":"3.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009678","HPA010095"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Golgi apparatus"],"Antibody RRID":{"HPA009678":"AB_2112580","HPA010095":"AB_1849952"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"}},{"Gene":"GRAMD4","Gene synonym":["DIP","KIAA0767"],"Ensembl":"ENSG00000075240","Gene description":"GRAM domain containing 4","Uniprot":["Q6IC98"],"Chromosome":"22","Position":"46576012-46679790","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"168.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"43.7","dendritic cells":"45.1","Distal enterocytes":"44.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.04e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"}},{"Gene":"GRIA1","Gene synonym":["GluA1","GLUR1","GLURA"],"Ensembl":"ENSG00000155511","Gene description":"Glutamate ionotropic receptor AMPA type subunit 1","Uniprot":["P42261"],"Chromosome":"5","Position":"153489615-153813869","Protein class":["FDA approved drug targets","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"83.7","retina":"32.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"317.3","Inhibitory neurons":"594.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"glioma":"9.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"3.5","Kidney cancer":"8.0"},"RNA tissue cell type enrichment":["Lung - Fibroblast_1","Testis - Early spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035202"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035202":"AB_2674516"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"}},{"Gene":"GRIA2","Gene synonym":["GluA2","GLUR2","GLURB"],"Ensembl":"ENSG00000120251","Gene description":"Glutamate ionotropic receptor AMPA type subunit 2","Uniprot":["P42262"],"Chromosome":"4","Position":"157204182-157366075","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Autism spectrum disorder","Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"78.4","retina":"29.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"324.5","Excitatory neurons":"1075.5","Horizontal cells":"248.7","Inhibitory neurons":"707.6","Oligodendrocyte precursor cells":"1059.9","Oligodendrocytes":"306.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"breast cancer":"2.7","endometrial cancer":"2.6","glioma":"6.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"21.9","Rhabdoid":"40.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells","Skin - Eccrine sweat gland cells","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008441"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008441":"AB_1078983"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"}},{"Gene":"GRIA3","Gene synonym":["GluA3","GLUR3","GLURC","MRX94"],"Ensembl":"ENSG00000125675","Gene description":"Glutamate ionotropic receptor AMPA type subunit 3","Uniprot":["P42263"],"Chromosome":"X","Position":"123184153-123490915","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"31.6","retina":"17.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"461.9","Inhibitory neurons":"387.3","Oligodendrocyte precursor cells":"368.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"10.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"4.4","liver cancer":"6.3","thyroid cancer":"5.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Breast - Fibroblasts","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Lung - Fibroblast_2","Pancreas - Alpha cells","Pancreas - Beta cells","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058659","HPA073344"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058659":"AB_2683791","HPA073344":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"}},{"Gene":"GRIA4","Gene synonym":["GluA4","GLUR4","GLURD"],"Ensembl":"ENSG00000152578","Gene description":"Glutamate ionotropic receptor AMPA type subunit 4","Uniprot":["P48058"],"Chromosome":"11","Position":"105609994-105982092","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"105.5","retina":"32.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"788.2","Horizontal cells":"241.6","Inhibitory neurons":"1022.9","Oligodendrocyte precursor cells":"723.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"5.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"10.6","Rhabdoid":"9.9"},"RNA tissue cell type enrichment":["Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063282"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Focal adhesion sites"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA063282":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"}},{"Gene":"GRID1","Gene synonym":["GluD1","KIAA1220"],"Ensembl":"ENSG00000182771","Gene description":"Glutamate ionotropic receptor delta type subunit 1","Uniprot":["Q9ULK0"],"Chromosome":"10","Position":"85599552-86366795","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"7.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"19","RNA single cell type specific nTPM":{"Astrocytes":"145.2","Excitatory neurons":"280.5","Inhibitory neurons":"294.7","Oligodendrocyte precursor cells":"302.8","Oligodendrocytes":"504.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"3.6","thyroid cancer":"6.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"2.3"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-3"}},{"Gene":"GRID2","Gene synonym":["GluD2","GluR-delta-2"],"Ensembl":"ENSG00000152208","Gene description":"Glutamate ionotropic receptor delta type subunit 2","Uniprot":["O43424"],"Chromosome":"4","Position":"92303966-93810157","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"40.2","testis":"34.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"777.2","Inhibitory neurons":"954.2","Late spermatids":"726.2","Microglial cells":"372.2","Oligodendrocyte precursor cells":"2221.4","Oligodendrocytes":"428.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"1.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"40.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"cerebellum":"68.3"},"Antibody":["HPA056253","HPA058538"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056253":"AB_2683079","HPA058538":"AB_2683747"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"GRIK1","Gene synonym":["GluK1","GLUR5"],"Ensembl":"ENSG00000171189","Gene description":"Glutamate ionotropic receptor kainate type subunit 1","Uniprot":["P39086"],"Chromosome":"21","Position":"29536933-29940033","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"adrenal gland":"12.5","brain":"32.6","retina":"38.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Inhibitory neurons":"2193.3","Oligodendrocyte precursor cells":"826.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"4.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014623","HPA073879"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA014623":"AB_1850305","HPA073879":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"}},{"Gene":"GRIK2","Gene synonym":["GluK2","GLUR6","MRT6"],"Ensembl":"ENSG00000164418","Gene description":"Glutamate ionotropic receptor kainate type subunit 2","Uniprot":["Q13002"],"Chromosome":"6","Position":"101181257-102070083","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"20","RNA tissue specific nTPM":{"brain":"93.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"26","RNA single cell type specific nTPM":{"Excitatory neurons":"714.0","Inhibitory neurons":"2316.8","Oligodendrocyte precursor cells":"1181.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"3.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"93.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"11.1","skin cancer":"13.2"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Kidney - Podocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014395","HPA014623","CAB022463"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022463":null,"HPA014395":"AB_1850303","HPA014623":"AB_1850305"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-4"}},{"Gene":"GRIK3","Gene synonym":["GluK3","GLUR7"],"Ensembl":"ENSG00000163873","Gene description":"Glutamate ionotropic receptor kainate type subunit 3","Uniprot":["Q13003"],"Chromosome":"1","Position":"36795527-37034515","Protein class":["FDA approved drug targets","Plasma proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.0","intestine":"7.8","pituitary gland":"9.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"38.4","Inhibitory neurons":"105.7","Oligodendrocyte precursor cells":"69.8","Schwann cells":"31.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"13.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"11.8","lung cancer":"7.9","Neuroblastoma":"6.7"},"RNA tissue cell type enrichment":["Adipose visceral - Smooth muscle cells","Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"}},{"Gene":"GRIK4","Gene synonym":["GluK4","GRIK","KA1"],"Ensembl":"ENSG00000149403","Gene description":"Glutamate ionotropic receptor kainate type subunit 4","Uniprot":["Q16099"],"Chromosome":"11","Position":"120511746-120988906","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"80.3","Excitatory neurons":"113.9","Inhibitory neurons":"42.6","Oligodendrocyte precursor cells":"187.7","Oligodendrocytes":"102.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"3.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Myeloma":"3.8"},"RNA tissue cell type enrichment":["Lung - Fibroblast_1","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074453"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074453":"AB_2732255"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"}},{"Gene":"GRIK5","Gene synonym":["GluK5","GRIK2","KA2"],"Ensembl":"ENSG00000105737","Gene description":"Glutamate ionotropic receptor kainate type subunit 5","Uniprot":["Q16478"],"Chromosome":"19","Position":"41998321-42069498","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"36.5","testis":"32.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"17.4","Bipolar cells":"20.4","Excitatory neurons":"31.9","Horizontal cells":"17.9","Inhibitory neurons":"30.4","Oligodendrocyte precursor cells":"30.3","Rod photoreceptor cells":"17.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"15.4","ovarian cancer":"6.6","thyroid cancer":"6.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"10.7","Neuroblastoma":"20.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074001"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA074001":"AB_2732248"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.23e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"}},{"Gene":"GRIN1","Gene synonym":["GluN1","NMDAR1"],"Ensembl":"ENSG00000176884","Gene description":"Glutamate ionotropic receptor NMDA type subunit 1","Uniprot":["Q05586"],"Chromosome":"9","Position":"137139154-137168756","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","RAS pathway related proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"49","RNA tissue specific nTPM":{"brain":"186.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Excitatory neurons":"130.7","Horizontal cells":"127.5","Inhibitory neurons":"131.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.9","prostate cancer":"1.8"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"186.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"4.5"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Prostate - Prostate glandular cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067773"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA067773":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"}},{"Gene":"GRIN2A","Gene synonym":["GluN2A","NMDAR2A"],"Ensembl":"ENSG00000183454","Gene description":"Glutamate ionotropic receptor NMDA type subunit 2A","Uniprot":["Q12879"],"Chromosome":"16","Position":"9753404-10182928","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"31.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Excitatory neurons":"827.5","Inhibitory neurons":"882.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"0.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"31.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Heart muscle - Cardiomyocytes","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022725"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022725":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"}},{"Gene":"GRIN2B","Gene synonym":["GluN2B","NMDAR2B"],"Ensembl":"ENSG00000273079","Gene description":"Glutamate ionotropic receptor NMDA type subunit 2B","Uniprot":["Q13224"],"Chromosome":"12","Position":"13437942-13982002","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"85","RNA tissue specific nTPM":{"brain":"36.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"616.4","Inhibitory neurons":"862.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"34","RNA brain regional specific nTPM":{"amygdala":"11.5","basal ganglia":"15.6","cerebral cortex":"36.1","hippocampal formation":"29.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.6"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069762"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069762":"AB_2686192"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"}},{"Gene":"GRIN2C","Gene synonym":["GluN2C","NMDAR2C"],"Ensembl":"ENSG00000161509","Gene description":"Glutamate ionotropic receptor NMDA type subunit 2C","Uniprot":["Q14957"],"Chromosome":"17","Position":"74842023-74861504","Protein class":["FDA approved drug targets","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"58.7","heart muscle":"18.6","thyroid gland":"16.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"134.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"2.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"14","RNA pig brain regional specific nTPM":{"cerebellum":"43.2"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"}},{"Gene":"GRIN2D","Gene synonym":["EB11","GluN2D","NMDAR2D","NR2D"],"Ensembl":"ENSG00000105464","Gene description":"Glutamate ionotropic receptor NMDA type subunit 2D","Uniprot":["O15399"],"Chromosome":"19","Position":"48393668-48444931","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"8.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Inhibitory neurons":"35.7","Oligodendrocyte precursor cells":"14.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009006"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009006":"AB_2279191"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"}},{"Gene":"GRIN3A","Gene synonym":["GluN3A"],"Ensembl":"ENSG00000198785","Gene description":"Glutamate ionotropic receptor NMDA type subunit 3A","Uniprot":["Q8TCU5"],"Chromosome":"9","Position":"101569352-101738647","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Inhibitory neurons":"215.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"prostate cancer":"3.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"3.2","prostate cancer":"3.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"}},{"Gene":"GRIN3B","Gene synonym":["GluN3B"],"Ensembl":"ENSG00000116032","Gene description":"Glutamate ionotropic receptor NMDA type subunit 3B","Uniprot":["O60391"],"Chromosome":"19","Position":"1000419-1009732","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.9","fallopian tube":"4.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"14.9","Respiratory ciliated cells":"48.6","Spermatogonia":"11.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"pons and medulla":"1.6"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"9","RNA pig brain regional specific nTPM":{"spinal cord":"4.8"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"}},{"Gene":"GRINA","Gene synonym":["HNRGW","LFG1","NMDARA1","TMBIM3"],"Ensembl":"ENSG00000178719","Gene description":"Glutamate ionotropic receptor NMDA type subunit associated protein 1","Uniprot":["Q7Z429"],"Chromosome":"8","Position":"143990056-143993415","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"435.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036980","HPA036981"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA036980":"AB_10696791","HPA036981":"AB_10962980"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"}},{"Gene":"GRM1","Gene synonym":["GPRC1A","mGlu1","MGLUR1","PPP1R85"],"Ensembl":"ENSG00000152822","Gene description":"Glutamate metabotropic receptor 1","Uniprot":["Q13255"],"Chromosome":"6","Position":"146027646-146437601","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"27.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"212.6","Inhibitory neurons":"135.2","Rod photoreceptor cells":"127.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"27.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015701"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA015701":"AB_1853917"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"}},{"Gene":"GRM2","Gene synonym":["GPRC1B","mGlu2","MGLUR2"],"Ensembl":"ENSG00000164082","Gene description":"Glutamate metabotropic receptor 2","Uniprot":["Q14416"],"Chromosome":"3","Position":"51707068-51718613","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"6.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"3.4","Excitatory neurons":"16.0","Horizontal cells":"7.7","Rod photoreceptor cells":"3.6","Spermatocytes":"3.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"testis cancer":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"3.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027868","HPA065166"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027868":null,"HPA065166":"AB_2685425"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"}},{"Gene":"GRM3","Gene synonym":["GPRC1C","mGlu3","MGLUR3"],"Ensembl":"ENSG00000198822","Gene description":"Glutamate metabotropic receptor 3","Uniprot":["Q14832"],"Chromosome":"7","Position":"86643914-86864884","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"79.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"19","RNA single cell type specific nTPM":{"Astrocytes":"397.9","Excitatory neurons":"268.0","Oligodendrocytes":"970.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"2.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"1.1"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"}},{"Gene":"GRM4","Gene synonym":["GPRC1D","mGlu4","MGLUR4"],"Ensembl":"ENSG00000124493","Gene description":"Glutamate metabotropic receptor 4","Uniprot":["Q14833"],"Chromosome":"6","Position":"34018643-34155622","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"93","RNA tissue specific nTPM":{"brain":"80.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"9.3","Horizontal cells":"19.9","Inhibitory neurons":"10.6","Late spermatids":"3.6","Spermatogonia":"4.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.7"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"cerebellum":"80.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"1.2"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"79.1"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"cerebellum":"138.8"},"Antibody":["CAB022096"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022096":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"}},{"Gene":"GRM5","Gene synonym":["GPRC1E","mGlu5","MGLUR5","PPP1R86"],"Ensembl":"ENSG00000168959","Gene description":"Glutamate metabotropic receptor 5","Uniprot":["P41594"],"Chromosome":"11","Position":"88504576-89065945","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"23.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"26","RNA single cell type specific nTPM":{"Excitatory neurons":"889.5","Inhibitory neurons":"945.7","Oligodendrocyte precursor cells":"996.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"14.9","basal ganglia":"17.3","cerebral cortex":"23.8","hippocampal formation":"20.4","white matter":"6.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Gallbladder cancer":"2.6"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GRM6","Gene synonym":["CSNB1B","GPRC1F","mGlu6","MGLUR6"],"Ensembl":"ENSG00000113262","Gene description":"Glutamate metabotropic receptor 6","Uniprot":["O15303"],"Chromosome":"5","Position":"178977587-178996206","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Congenital stationary night blindness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"57","RNA tissue specific nTPM":{"retina":"42.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"35","RNA single cell type specific nTPM":{"Bipolar cells":"490.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"Brain cancer":"1.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014511"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014511":"AB_2669025"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"}},{"Gene":"GRM7","Gene synonym":["GLUR7","GPRC1G","mGlu7","MGLUR7","PPP1R87"],"Ensembl":"ENSG00000196277","Gene description":"Glutamate metabotropic receptor 7","Uniprot":["Q14831"],"Chromosome":"3","Position":"6770001-7741533","Protein class":["G-protein coupled receptors","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cardiomyopathy","Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.1","parathyroid gland":"4.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Excitatory neurons":"763.7","Inhibitory neurons":"580.5","Oligodendrocyte precursor cells":"1138.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015964"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015964":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"}},{"Gene":"GRM8","Gene synonym":["GLUR8","GPRC1H","mGlu8","MGLUR8"],"Ensembl":"ENSG00000179603","Gene description":"Glutamate metabotropic receptor 8","Uniprot":["O00222"],"Chromosome":"7","Position":"126438598-127253093","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"choroid plexus":"44.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"45.7","Excitatory neurons":"103.0","Inhibitory neurons":"131.3","Late spermatids":"77.5","Oligodendrocyte precursor cells":"31.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"2.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"6.2","thyroid cancer":"6.3"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051481"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051481":"AB_2681499"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"}},{"Gene":"GRPR","Gene synonym":["BB2","BB2R"],"Ensembl":"ENSG00000126010","Gene description":"Gastrin releasing peptide receptor","Uniprot":["P30550"],"Chromosome":"X","Position":"16123565-16153518","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"pancreas":"20.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Inhibitory neurons":"6.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"breast cancer":"6.6"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hypothalamus":"1.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"12.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"2.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069604"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA069604":"AB_2686158"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"}},{"Gene":"GSG1","Gene synonym":["MGC3146"],"Ensembl":"ENSG00000111305","Gene description":"Germ cell associated 1","Uniprot":["Q2KHT4"],"Chromosome":"12","Position":"13083532-13103683","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"testis":"429.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Late spermatids":"11122.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Rhabdoid":"113.6"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-3"}},{"Gene":"GSG1L","Gene synonym":["KTSR5831","MGC18079","PRO19651"],"Ensembl":"ENSG00000169181","Gene description":"GSG1 like","Uniprot":["Q6UXU4"],"Chromosome":"16","Position":"27787528-28063714","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"22.5","heart muscle":"23.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"25.5","Horizontal cells":"19.2","Oligodendrocyte precursor cells":"85.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"3.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"4.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014479"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014479":"AB_2247974"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"}},{"Gene":"GSG1L2","Gene synonym":[],"Ensembl":"ENSG00000214978","Gene description":"GSG1 like 2","Uniprot":["A8MUP6"],"Chromosome":"17","Position":"9802386-9822071","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"1.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"95","RNA cancer specific FPKM":{"renal cancer":"4.7"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"1.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GSK3B","Gene synonym":[],"Ensembl":"ENSG00000082701","Gene description":"Glycogen synthase kinase 3 beta","Uniprot":["P49841"],"Chromosome":"3","Position":"119821321-120094994","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms","Carbohydrate metabolism","Differentiation","Glycogen metabolism","Neurogenesis","Wnt signaling pathway"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Signal transduction inhibitor","Transferase"],"Disease involvement":["Alzheimer disease","Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"215.5","Inhibitory neurons":"240.6","Oligodendrocyte precursor cells":"231.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006495","CAB016263","HPA028017"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 69: BICR 18 - Unknown function","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016263":"AB_2279451","HPA006495":null,"HPA028017":"AB_10600708"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.20e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.52e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"}},{"Gene":"GSTCD","Gene synonym":["FLJ13273"],"Ensembl":"ENSG00000138780","Gene description":"Glutathione S-transferase C-terminal domain containing","Uniprot":["Q8NEC7"],"Chromosome":"4","Position":"105708778-105847725","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"106.7","Late spermatids":"69.3","Oligodendrocyte precursor cells":"51.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"5.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046160","HPA061782"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA046160":"AB_10961048","HPA061782":"AB_2797265"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"}},{"Gene":"GSTK1","Gene synonym":["GST13"],"Ensembl":"ENSG00000197448","Gene description":"Glutathione S-transferase kappa 1","Uniprot":["Q9Y2Q3"],"Chromosome":"7","Position":"143244093-143270854","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"1159.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006311","HPA022904"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA006311":"AB_1849786","HPA022904":"AB_1849787"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.41e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.10e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"}},{"Gene":"GTF3C1","Gene synonym":["TFIIIC220"],"Ensembl":"ENSG00000077235","Gene description":"General transcription factor IIIC subunit 1","Uniprot":["Q12789"],"Chromosome":"16","Position":"27459555-27549913","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"91.3","NK-cells":"121.6","Prostatic glandular cells":"100.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"31.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skin - Keratinocyte (other)","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051617","HPA075900"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA051617":"AB_2681553","HPA075900":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.73e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.56e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-3"}},{"Gene":"GTF3C4","Gene synonym":["KAT12","TFIIIC90"],"Ensembl":"ENSG00000125484","Gene description":"General transcription factor IIIC subunit 4","Uniprot":["Q9UKN8"],"Chromosome":"9","Position":"132670035-132694953","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Transcription"],"Molecular function":["Acyltransferase","DNA-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069369"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA069369":"AB_2686130"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.99e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"GTPBP3","Gene synonym":["FLJ14700","GTPBG3","MSS1","MTGP1","THDF1"],"Ensembl":"ENSG00000130299","Gene description":"GTP binding protein 3, mitochondrial","Uniprot":["Q969Y2"],"Chromosome":"19","Position":"17334920-17342731","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042158"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA042158":"AB_10964400"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.81e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.64e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"GUCY1A2","Gene synonym":["GC-SA2","GUC1A2"],"Ensembl":"ENSG00000152402","Gene description":"Guanylate cyclase 1 soluble subunit alpha 2","Uniprot":["P33402"],"Chromosome":"11","Position":"106674019-107018476","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["cGMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.4","placenta":"17.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"348.3","Inhibitory neurons":"138.7","Oligodendrocyte precursor cells":"199.8","Smooth muscle cells":"83.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Kidney - Fibroblasts","Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009534"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009534":"AB_2279509"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"}},{"Gene":"GUCY1B1","Gene synonym":["GC-S-beta-1","GC-SB3","GUC1B3","GUCY1B3"],"Ensembl":"ENSG00000061918","Gene description":"Guanylate cyclase 1 soluble subunit beta 1","Uniprot":["Q02153"],"Chromosome":"4","Position":"155758992-155807811","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["cGMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"50.0","Excitatory neurons":"68.8","Inhibitory neurons":"57.6","Sertoli cells":"71.9","Smooth muscle cells":"93.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"intermediate monocyte":"7.2","non-classical monocyte":"23.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"monocytes":"23.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010890","HPA020870"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB010890":"AB_259911","HPA020870":"AB_1850444"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.23e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-3"}},{"Gene":"GUCY2C","Gene synonym":["GUC2C","STAR"],"Ensembl":"ENSG00000070019","Gene description":"Guanylate cyclase 2C","Uniprot":["P25092"],"Chromosome":"12","Position":"14612632-14696599","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["cGMP biosynthesis"],"Molecular function":["Lyase","Receptor"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"20","RNA tissue specific nTPM":{"intestine":"68.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Distal enterocytes":"33.6","Enteroendocrine cells":"129.8","Intestinal goblet cells":"58.2","Paneth cells":"101.3","Proximal enterocytes":"71.5","Undifferentiated cells":"40.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"23.9","stomach cancer":"9.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Bile duct cancer":"10.3","colorectal cancer":"17.9","Gastric cancer":"8.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"midbrain":"1.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037655","HPA073759"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA037655":"AB_10672388","HPA073759":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.37e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"}},{"Gene":"GUCY2D","Gene synonym":["CORD6","CYGD","GUC1A4","GUC2D","LCA","LCA1","retGC","RETGC-1","ROS-GC1"],"Ensembl":"ENSG00000132518","Gene description":"Guanylate cyclase 2D, retinal","Uniprot":["Q02846"],"Chromosome":"17","Position":"8002615-8020342","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["cGMP biosynthesis","Sensory transduction","Vision"],"Molecular function":["Lyase"],"Disease involvement":["Cone-rod dystrophy","Congenital stationary night blindness","Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"retina":"34.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"39.6","Late spermatids":"16.5","Rod photoreceptor cells":"53.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"31","RNA blood cell specific nTPM":{"plasmacytoid DC":"8.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"50","RNA blood lineage specific nTPM":{"dendritic cells":"8.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"1.2"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"GUCY2F","Gene synonym":["CYGF","GC-F","GUC2DL","RetGC-2","ROS-GC2"],"Ensembl":"ENSG00000101890","Gene description":"Guanylate cyclase 2F, retinal","Uniprot":["P51841"],"Chromosome":"X","Position":"109372906-109482086","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["cGMP biosynthesis","Sensory transduction","Vision"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"145","RNA tissue specific nTPM":{"retina":"42.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"30.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GUK1","Gene synonym":[],"Ensembl":"ENSG00000143774","Gene description":"Guanylate kinase 1","Uniprot":["Q16774"],"Chromosome":"1","Position":"228139962-228148984","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"3360.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028118","HPA048587","HPA068324"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA028118":"AB_2756308","HPA048587":"AB_2680453","HPA068324":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.85e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"}},{"Gene":"GYG1","Gene synonym":["GYG"],"Ensembl":"ENSG00000163754","Gene description":"Glycogenin 1","Uniprot":["P46976"],"Chromosome":"3","Position":"148991408-149031775","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycogen biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"560.0","tongue":"357.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"276.0","Early spermatids":"272.8","Late spermatids":"374.1","Spermatocytes":"246.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030497","HPA073229"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"30000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA030497":"AB_10602326","HPA073229":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.15e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"}},{"Gene":"GYPA","Gene synonym":["CD235a","GPA","MN","MNS"],"Ensembl":"ENSG00000170180","Gene description":"Glycophorin A (MNS blood group)","Uniprot":["P02724"],"Chromosome":"4","Position":"144109303-144140751","Protein class":["Blood group antigen proteins","CD markers","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Blood group antigen","Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"38","RNA tissue specific nTPM":{"bone marrow":"156.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"308","RNA single cell type specific nTPM":{"Erythroid cells":"1211.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"1.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"Leukemia":"33.3"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Erythroid cells","Lung - Neutrophil_1"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002658","HPA014811"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002658":null,"HPA014811":"AB_1849827"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GYPB","Gene synonym":["CD235b","GPB","MNS","SS"],"Ensembl":"ENSG00000250361","Gene description":"Glycophorin B (MNS blood group)","Uniprot":["P06028"],"Chromosome":"4","Position":"143996104-144019380","Protein class":["Blood group antigen proteins","CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Blood group antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"bone marrow":"63.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"307","RNA single cell type specific nTPM":{"Erythroid cells":"924.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"163","RNA cell line specific nTPM":{"Leukemia":"19.6"},"RNA tissue cell type enrichment":["Liver - Erythroid cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"GYPC","Gene synonym":["CD236","CD236R","Ge","GPC","GYPD"],"Ensembl":"ENSG00000136732","Gene description":"Glycophorin C (Gerbich blood group)","Uniprot":["P04921"],"Chromosome":"2","Position":"126656133-126696667","Protein class":["Blood group antigen proteins","CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Blood group antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"441.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"1194.3","Hofbauer cells":"465.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"66.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"218.8","skin cancer":"272.6"},"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008965","CAB009445"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"970000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB009445":"AB_2116251","HPA008965":"AB_1078455"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"}},{"Gene":"GYPE","Gene synonym":["GPE","MNS"],"Ensembl":"ENSG00000197465","Gene description":"Glycophorin E (MNS blood group)","Uniprot":["P15421"],"Chromosome":"4","Position":"143870864-143905563","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"13.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Erythroid cells":"128.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"1.4"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"9.3"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"}},{"Gene":"GYS1","Gene synonym":["GSY","GYS"],"Ensembl":"ENSG00000104812","Gene description":"Glycogen synthase 1","Uniprot":["P13807"],"Chromosome":"19","Position":"48968130-48993310","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Glycogen biosynthesis"],"Molecular function":["Allosteric enzyme","Glycosyltransferase","Transferase"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"heart muscle":"118.5","skeletal muscle":"319.4","tongue":"201.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"55.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB007793","HPA041598"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Microtubules","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB007793":"AB_562291","HPA041598":"AB_2677571"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.46e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"}},{"Gene":"HACD1","Gene synonym":["CAP","PTPLA"],"Ensembl":"ENSG00000165996","Gene description":"3-hydroxyacyl-CoA dehydratase 1","Uniprot":["B0YJ81"],"Chromosome":"10","Position":"17589032-17617374","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Developmental protein","Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"73.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"81.9","Cardiomyocytes":"200.8","Melanocytes":"109.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"T-reg":"55.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"T-cells":"55.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Colon - Smooth muscle cells","Prostate - Smooth muscle cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"}},{"Gene":"HACD2","Gene synonym":["PTPLB"],"Ensembl":"ENSG00000206527","Gene description":"3-hydroxyacyl-CoA dehydratase 2","Uniprot":["Q6Y1H2"],"Chromosome":"3","Position":"123490820-123585053","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019282"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB019282":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.59e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"}},{"Gene":"HACD3","Gene synonym":["B-ind1","HSPC121","PTPLAD1"],"Ensembl":"ENSG00000074696","Gene description":"3-hydroxyacyl-CoA dehydratase 3","Uniprot":["Q9P035"],"Chromosome":"15","Position":"65530418-65578349","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014837","HPA060347"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA014837":"AB_1855914","HPA060347":"AB_2684260"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.09e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"}},{"Gene":"HACD4","Gene synonym":["Em:AL662879.1","PTPLAD2"],"Ensembl":"ENSG00000188921","Gene description":"3-hydroxyacyl-CoA dehydratase 4","Uniprot":["Q5VWC8"],"Chromosome":"9","Position":"20999509-21031640","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"12.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"86.4","Kupffer cells":"84.8","Langerhans cells":"71.4","Macrophages":"75.0","monocytes":"90.8","Respiratory ciliated cells":"78.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058666"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058666":"AB_2683793"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.14e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.77e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"}},{"Gene":"HADH","Gene synonym":["HADH1","HADHSC","SCHAD"],"Ensembl":"ENSG00000138796","Gene description":"Hydroxyacyl-CoA dehydrogenase","Uniprot":["Q16836"],"Chromosome":"4","Position":"107989714-108035174","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase","Transferase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"280.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"292.5","Hepatocytes":"314.6","Proximal enterocytes":"392.7","Proximal tubular cells":"252.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Skeletal muscle - Skeletal myocytes","Skin - Sebaceous gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039588","HPA043888"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA039588":"AB_10673425","HPA043888":"AB_2678716"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"}},{"Gene":"HADHA","Gene synonym":["GBP","LCEH","LCHAD","MTPA"],"Ensembl":"ENSG00000084754","Gene description":"Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha","Uniprot":["P40939"],"Chromosome":"2","Position":"26190635-26244672","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Lyase","Multifunctional enzyme","Oxidoreductase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"502.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"507.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015536","HPA056070"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"470000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA015536":"AB_1850473","HPA056070":"AB_2683026"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.68e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"}},{"Gene":"HAO2","Gene synonym":["GIG16","HAOX2"],"Ensembl":"ENSG00000116882","Gene description":"Hydroxyacid oxidase 2","Uniprot":["Q9NYQ3"],"Chromosome":"1","Position":"119368779-119394130","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"kidney":"303.7","liver":"425.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Hepatocytes":"280.3","Proximal tubular cells":"391.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"26","RNA cancer specific FPKM":{"liver cancer":"25.6","renal cancer":"11.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050355"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA050355":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-4"}},{"Gene":"HAPLN3","Gene synonym":["EXLD1","HsT19883"],"Ensembl":"ENSG00000140511","Gene description":"Hyaluronan and proteoglycan link protein 3","Uniprot":["Q96S86"],"Chromosome":"15","Position":"88877294-88895597","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"1166.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"50.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"50.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Uterine cancer":"51.2"},"RNA tissue cell type enrichment":["Colon - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039237"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039237":"AB_10805357"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.18e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"}},{"Gene":"HAS1","Gene synonym":["HAS"],"Ensembl":"ENSG00000105509","Gene description":"Hyaluronan synthase 1","Uniprot":["Q92839"],"Chromosome":"19","Position":"51713112-51723991","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"49.6","ovary":"20.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Thymic epithelial cells":"259.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"2.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"2.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"granulocytes":"2.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"3.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067602"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA067602":"AB_2685871"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"}},{"Gene":"HAS2","Gene synonym":[],"Ensembl":"ENSG00000170961","Gene description":"Hyaluronan synthase 2","Uniprot":["Q92819"],"Chromosome":"8","Position":"121612116-121641440","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"22.7","urinary bladder":"20.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"100.2","granulocytes":"48.8","Langerhans cells":"32.8","Melanocytes":"34.8","Pancreatic endocrine cells":"91.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052060"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA052060":"AB_2681712"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"}},{"Gene":"HAS3","Gene synonym":[],"Ensembl":"ENSG00000103044","Gene description":"Hyaluronan synthase 3","Uniprot":["O00219"],"Chromosome":"16","Position":"69105653-69118719","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"33.5","urinary bladder":"92.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"120.8","Basal respiratory cells":"103.8","Squamous epithelial cells":"27.8","Suprabasal keratinocytes":"92.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"cervical cancer":"17.1","head and neck cancer":"44.9","lung cancer":"23.3","urothelial cancer":"31.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"180.2"},"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031554","CAB033850"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB033850":"AB_2116418","HPA031554":"AB_10670703"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-3"}},{"Gene":"HAUS2","Gene synonym":["C15orf25","CEP27","FLJ10460","HsT17025"],"Ensembl":"ENSG00000137814","Gene description":"HAUS augmin like complex subunit 2","Uniprot":["Q9NVX0"],"Chromosome":"15","Position":"42548828-42569994","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"36.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039965"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA039965":"AB_10673025"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"}},{"Gene":"HAUS7","Gene synonym":["UCHL5IP","UIP1"],"Ensembl":"ENSG00000213397","Gene description":"HAUS augmin like complex subunit 7","Uniprot":["Q99871"],"Chromosome":"X","Position":"153447666-153495516","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"44.0","Oligodendrocyte precursor cells":"30.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003614"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane","Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA003614":"AB_1080368"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.12e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.94e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"}},{"Gene":"HAVCR1","Gene synonym":["CD365","HAVCR","HAVCR-1","KIM1","TIM-1","TIM1","TIMD1"],"Ensembl":"ENSG00000113249","Gene description":"Hepatitis A virus cellular receptor 1","Uniprot":["Q96D42"],"Chromosome":"5","Position":"157029413-157059119","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"4.6","kidney":"7.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1.9","Inhibitory neurons":"1.3","Microglial cells":"5.5","Oligodendrocytes":"1.7","Proximal tubular cells":"2.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"renal cancer":"26.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Kidney cancer":"196.5"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007173","CAB075697"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":155000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB075697":null,"HPA007173":"AB_1080282"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.81e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-4"}},{"Gene":"HAVCR2","Gene synonym":["CD366","FLJ14428","Tim-3","TIM3","TIMD3"],"Ensembl":"ENSG00000135077","Gene description":"Hepatitis A virus cellular receptor 2","Uniprot":["Q8TDQ0"],"Chromosome":"5","Position":"157085832-157142869","Protein class":["CD markers","Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity","Inflammatory response","Innate immunity"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"32.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"146.7","Langerhans cells":"78.0","Macrophages":"84.9","monocytes":"45.1","NK-cells":"136.3","Proximal tubular cells":"58.3","Schwann cells":"93.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"53.8","intermediate monocyte":"57.9","myeloid DC":"137.9","NK-cell":"97.1","non-classical monocyte":"36.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"137.9","monocytes":"57.9","NK-cells":"97.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"lymphoma":"13.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Proximal tubular cells","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026003"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9900000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026003":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"HBEGF","Gene synonym":["DTR","DTS","HEGFL"],"Ensembl":"ENSG00000113070","Gene description":"Heparin binding EGF like growth factor","Uniprot":["Q99075"],"Chromosome":"5","Position":"140332843-140346603","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor","Heparin-binding","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"urinary bladder":"128.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Squamous epithelial cells":"300.2","Suprabasal keratinocytes":"218.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"intermediate monocyte":"2.2","myeloid DC":"1.6","non-classical monocyte":"1.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"1.6","monocytes":"2.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053243"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":118000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053243":"AB_2682086"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.41e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.09e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.00e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"}},{"Gene":"HBS1L","Gene synonym":["DKFZp434g247","EF-1a","eRF3c","ERFS","HBS1","HSPC276","KIAA1038"],"Ensembl":"ENSG00000112339","Gene description":"HBS1 like translational GTPase","Uniprot":["Q9Y450"],"Chromosome":"6","Position":"134960378-135103056","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein biosynthesis","Translation regulation"],"Molecular function":["Elongation factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"187.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029728","HPA029729"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9200","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nuclear bodies","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029728":"AB_10611112","HPA029729":"AB_10601228"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.77e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"}},{"Gene":"HCAR1","Gene synonym":["FKSG80","GPR104","GPR81","HCA1","LACR1","TA-GPCR"],"Ensembl":"ENSG00000196917","Gene description":"Hydroxycarboxylic acid receptor 1","Uniprot":["Q9BXC0"],"Chromosome":"12","Position":"122726076-122730844","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"breast":"11.5","parathyroid gland":"40.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"24.9","Breast glandular cells":"7.6","Breast myoepithelial cells":"4.6","Early spermatids":"7.4","Extravillous trophoblasts":"4.2","Late spermatids":"7.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"7.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"16.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Breast glandular cells","Lung - Respiratory ciliated cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.61e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"}},{"Gene":"HCAR2","Gene synonym":["GPR109A","HCA2","HM74A","NIACR1","Puma-g","PUMAG"],"Ensembl":"ENSG00000182782","Gene description":"Hydroxycarboxylic acid receptor 2","Uniprot":["Q8TDS4"],"Chromosome":"12","Position":"122701293-122703357","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"40.8","skin 1":"30.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"56.3","Basal prostatic cells":"156.2","Basal respiratory cells":"47.4","Basal squamous epithelial cells":"99.7","Langerhans cells":"142.8","Suprabasal keratinocytes":"66.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"cervical cancer":"12.6","head and neck cancer":"16.1","lung cancer":"6.4","urothelial cancer":"9.2"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"5.9"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"176.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"176.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"20.9","Esophageal cancer":"22.9","head and neck cancer":"50.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Lung - NK-cells (Lung)","Skin - Keratinocyte (other)","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028660"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA028660":"AB_10602139"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"}},{"Gene":"HCAR3","Gene synonym":["GPR109B","HCA3","HM74"],"Ensembl":"ENSG00000255398","Gene description":"Hydroxycarboxylic acid receptor 3","Uniprot":["P49019"],"Chromosome":"12","Position":"122714756-122716811","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"27.4","esophagus":"16.8","lymphoid tissue":"19.6","skin 1":"17.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"79.7","Basal prostatic cells":"192.2","Basal respiratory cells":"54.1","Basal squamous epithelial cells":"139.8","Langerhans cells":"72.1","Squamous epithelial cells":"45.9","Suprabasal keratinocytes":"87.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"2.1","head and neck cancer":"2.5","lung cancer":"1.0","urothelial cancer":"1.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"4.7"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"58.6","neutrophil":"177.2","non-classical monocyte":"84.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"50","RNA blood lineage specific nTPM":{"granulocytes":"177.2","monocytes":"84.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bladder cancer":"7.1","cervical cancer":"3.9","Esophageal cancer":"4.9","Gallbladder cancer":"6.6","head and neck cancer":"12.4"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Lung - NK-cells (Lung)","Prostate - Urothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028660"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA028660":"AB_10602139"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"}},{"Gene":"HCN1","Gene synonym":["BCNG-1","BCNG1","HAC-2"],"Ensembl":"ENSG00000164588","Gene description":"Hyperpolarization activated cyclic nucleotide gated potassium channel 1","Uniprot":["O60741"],"Chromosome":"5","Position":"45254948-45696498","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Potassium channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"7.2","retina":"17.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"662.5","Inhibitory neurons":"749.6","Rod photoreceptor cells":"201.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"7.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"1.4"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019195"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019195":"AB_2670094"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"HCN2","Gene synonym":["BCNG-2","BCNG2","HAC-1"],"Ensembl":"ENSG00000099822","Gene description":"Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2","Uniprot":["Q9UL51"],"Chromosome":"19","Position":"589881-617159","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Potassium channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"146.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"55.5","Excitatory neurons":"12.6","Horizontal cells":"28.2","Inhibitory neurons":"18.3","Oligodendrocytes":"58.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"8.7","melanoma":"5.7","renal cancer":"2.8","testis cancer":"4.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Heart muscle - Cardiomyocytes","Pancreas - Alpha cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-3"}},{"Gene":"HCN3","Gene synonym":["KIAA1535"],"Ensembl":"ENSG00000143630","Gene description":"Hyperpolarization activated cyclic nucleotide gated potassium channel 3","Uniprot":["Q9P1Z3"],"Chromosome":"1","Position":"155277463-155289848","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Potassium channel","Sodium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"14.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"9.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"10.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026584"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026584":"AB_1850534"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.93e-4"}},{"Gene":"HCN4","Gene synonym":[],"Ensembl":"ENSG00000138622","Gene description":"Hyperpolarization activated cyclic nucleotide gated potassium channel 4","Uniprot":["Q9Y3Q4"],"Chromosome":"15","Position":"73319859-73368958","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Potassium channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Brugada syndrome","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"brain":"8.5","heart muscle":"8.4","testis":"7.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"16.9","Late spermatids":"54.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"testis cancer":"3.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"1.6","testis cancer":"1.2"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073174"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA073174":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"}},{"Gene":"HCRTR1","Gene synonym":["OX1R"],"Ensembl":"ENSG00000121764","Gene description":"Hypocretin receptor 1","Uniprot":["O43613"],"Chromosome":"1","Position":"31617686-31632518","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"4.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"hypothalamus":"1.5","medulla oblongata":"1.0","midbrain":"3.6","pons":"3.7","thalamus":"1.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014018"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014018":"AB_1854810"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"HCRTR2","Gene synonym":["OX2R"],"Ensembl":"ENSG00000137252","Gene description":"Hypocretin receptor 2","Uniprot":["O43614"],"Chromosome":"6","Position":"55106460-55282617","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"7.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"11.5","Inhibitory neurons":"18.0","Peritubular cells":"4.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054516"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054516":"AB_2682513"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"HCST","Gene synonym":["DAP10","DKFZP586C1522","KAP10","PIK3AP"],"Ensembl":"ENSG00000126264","Gene description":"Hematopoietic cell signal transducer","Uniprot":["Q9UBK5"],"Chromosome":"19","Position":"35902529-35904377","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"253.7","lymphoid tissue":"115.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"355.0","Hofbauer cells":"699.5","Kupffer cells":"383.0","Langerhans cells":"721.5","Macrophages":"366.5","monocytes":"418.9","NK-cells":"1332.5","T-cells":"721.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"Leukemia":"85.3","lymphoma":"47.2","Myeloma":"32.8"},"RNA tissue cell type enrichment":["Skeletal muscle - Macrophages","Testis - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034435","HPA063026"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Golgi apparatus","Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB034435":"AB_2117803","HPA063026":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.70e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"}},{"Gene":"HDAC10","Gene synonym":["DKFZP761B039"],"Ensembl":"ENSG00000100429","Gene description":"Histone deacetylase 10","Uniprot":["Q969S8"],"Chromosome":"22","Position":"50245183-50251405","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Autophagy","DNA damage","DNA recombination","DNA repair"],"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019662","CAB045977"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB045977":"AB_11124034","HPA019662":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.46e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.45e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.25e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.74e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"}},{"Gene":"HEATR5A","Gene synonym":["C14orf125","DKFZP434I1735"],"Ensembl":"ENSG00000129493","Gene description":"HEAT repeat containing 5A","Uniprot":["Q86XA9"],"Chromosome":"14","Position":"31291788-31420550","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"56.6","Oligodendrocyte precursor cells":"65.0","Oligodendrocytes":"91.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"120.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"120.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049539"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049539":"AB_2680809"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"}},{"Gene":"HEATR5B","Gene synonym":["DKFZp686P15184","KIAA1414"],"Ensembl":"ENSG00000008869","Gene description":"HEAT repeat containing 5B","Uniprot":["Q9P2D3"],"Chromosome":"2","Position":"36968383-37084372","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"61.4","Inhibitory neurons":"57.6","Oligodendrocytes":"65.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042025","HPA055639"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6800","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nuclear speckles","Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042025":"AB_10959880","HPA055639":"AB_2682870"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"}},{"Gene":"HEATR6","Gene synonym":["ABC1","FLJ22087"],"Ensembl":"ENSG00000068097","Gene description":"HEAT repeat containing 6","Uniprot":["Q6AI08"],"Chromosome":"17","Position":"60041008-60078922","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030789","HPA062157"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA030789":"AB_10601660","HPA062157":"AB_2684700"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.03e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.02e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"}},{"Gene":"HECTD1","Gene synonym":["KIAA1131"],"Ensembl":"ENSG00000092148","Gene description":"HECT domain E3 ubiquitin protein ligase 1","Uniprot":["Q9ULT8"],"Chromosome":"14","Position":"31100112-31207804","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"218.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002929","HPA054461"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA002929":"AB_1850574","HPA054461":"AB_2682496"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.20e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-3"}},{"Gene":"HECTD4","Gene synonym":["C12orf51","FLJ34154","KIAA0614"],"Ensembl":"ENSG00000173064","Gene description":"HECT domain E3 ubiquitin protein ligase 4","Uniprot":[],"Chromosome":"12","Position":"112160188-112382439","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"187.6","Inhibitory neurons":"175.8","Oligodendrocyte precursor cells":"104.5","Oligodendrocytes":"131.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041062","HPA045473"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA041062":"AB_2677281","HPA045473":"AB_2679338"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.97e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-3"}},{"Gene":"HEG1","Gene synonym":["HEG","KIAA1237"],"Ensembl":"ENSG00000173706","Gene description":"Heart development protein with EGF like domains 1","Uniprot":["Q9ULI3"],"Chromosome":"3","Position":"124965710-125055997","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"255.1","Endothelial cells":"131.0","Thymic epithelial cells":"194.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Endothelial cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010952","HPA011559"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"510000000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA010952":"AB_2668389","HPA011559":"AB_1850580"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.93e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.16e-4"}},{"Gene":"HELT","Gene synonym":["bHLHb44","HCM1228","HESL","MEGANE","Mgn"],"Ensembl":"ENSG00000187821","Gene description":"Helt bHLH transcription factor","Uniprot":["A6NFD8"],"Chromosome":"4","Position":"185018841-185020804","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Repressor"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"1.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Alveolar cells type 1":"2.1","Distal tubular cells":"6.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036188","HPA036189"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036188":"AB_10672237","HPA036189":"AB_2674997"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"HELZ","Gene synonym":["DHRC","HUMORF5","KIAA0054"],"Ensembl":"ENSG00000198265","Gene description":"Helicase with zinc finger","Uniprot":["P42694"],"Chromosome":"17","Position":"67070444-67245989","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Helicase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028276"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Nucleoli rim","Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Plasma membrane","Actin filaments"],"Antibody RRID":{"HPA028276":"AB_10601814"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"}},{"Gene":"HENMT1","Gene synonym":["C1orf59","FLJ30525","HEN1"],"Ensembl":"ENSG00000162639","Gene description":"HEN methyltransferase 1","Uniprot":["Q5T8I9"],"Chromosome":"1","Position":"108648290-108661526","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["RNA-mediated gene silencing"],"Molecular function":["Methyltransferase","RNA-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"72.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"38.9","Spermatocytes":"172.9","Spermatogonia":"117.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"19","RNA pig brain regional specific nTPM":{"cerebellum":"9.1"},"Antibody":["HPA028464","HPA028497"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Plasma membrane","Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA028464":"AB_10600103","HPA028497":"AB_10601552"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.95e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"}},{"Gene":"HEPACAM","Gene synonym":["FLJ25530","GLIALCAM"],"Ensembl":"ENSG00000165478","Gene description":"Hepatic and glial cell adhesion molecule","Uniprot":["Q14CZ8"],"Chromosome":"11","Position":"124919205-124936412","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Cell cycle","Growth arrest","Growth regulation"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"222.6","choroid plexus":"79.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Astrocytes":"179.0","Oligodendrocyte precursor cells":"69.8","Oligodendrocytes":"154.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"glioma":"29.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"1.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Skin - Adipocytes (Skin)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017613","CAB025486"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB025486":null,"HPA017613":"AB_1850595"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"HEPACAM2","Gene synonym":["FLJ38683"],"Ensembl":"ENSG00000188175","Gene description":"HEPACAM family member 2","Uniprot":["A8MVW5"],"Chromosome":"7","Position":"93188534-93226469","Protein class":["Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"96.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Enteroendocrine cells":"124.8","Intestinal goblet cells":"390.3","Paneth cells":"368.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"8.4","pancreatic cancer":"10.7","renal cancer":"10.6","stomach cancer":"5.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Gastric cancer":"11.2","lung cancer":"28.3"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Colon enterocytes","Kidney - Intercalated cells","Lung - Respiratory ciliated cells","Pancreas - Alpha cells","Pancreas - Beta cells","Stomach - Gastric enteroendocrine cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012381"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Vesicles","Mitotic spindle"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA012381":"AB_1853037"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.73e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"}},{"Gene":"HEPH","Gene synonym":["CPL","KIAA0698"],"Ensembl":"ENSG00000089472","Gene description":"Hephaestin","Uniprot":["Q9BQS7"],"Chromosome":"X","Position":"66162549-66268867","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Copper transport","Ion transport","Iron transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"81.9","smooth muscle":"82.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"75.6","Distal enterocytes":"133.8","Enteroendocrine cells":"49.6","Intestinal goblet cells":"105.9","Paneth cells":"68.8","Proximal enterocytes":"125.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"37.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"38.0","testis cancer":"68.6"},"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Colon - Smooth muscle cells","Kidney - Fibroblasts","Liver - Hepatic stellate cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005824"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3700000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA005824":"AB_1850603"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.00e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"}},{"Gene":"HEPHL1","Gene synonym":["DKFZp686F22190"],"Ensembl":"ENSG00000181333","Gene description":"Hephaestin like 1","Uniprot":["Q6MZM0"],"Chromosome":"11","Position":"94021354-94114208","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Copper transport","Ion transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"esophagus":"4.5","lymphoid tissue":"9.5","skin 1":"3.8","vagina":"4.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"17.1","granulocytes":"4.9","Serous glandular cells":"22.4","Suprabasal keratinocytes":"6.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"head and neck cancer":"20.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Bladder cancer":"4.6","colorectal cancer":"4.1","head and neck cancer":"9.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"12","RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.2"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031517"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031517":"AB_10603769"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.94e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"HERC1","Gene synonym":["p532","p619"],"Ensembl":"ENSG00000103657","Gene description":"HECT and RLD domain containing E3 ubiquitin protein ligase family member 1","Uniprot":["Q15751"],"Chromosome":"15","Position":"63608618-63833948","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transport","Ubl conjugation pathway"],"Molecular function":["Guanine-nucleotide releasing factor","Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"452.0","Inhibitory neurons":"330.5","Oligodendrocytes":"190.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049749"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049749":"AB_2680866"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.87e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.66e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.36e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"}},{"Gene":"HERC2","Gene synonym":["D15F37S1","jdf2","p528"],"Ensembl":"ENSG00000128731","Gene description":"HECT and RLD domain containing E3 ubiquitin protein ligase 2","Uniprot":["O95714"],"Chromosome":"15","Position":"28111040-28322179","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017188","HPA048389","HPA074166"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB017188":null,"HPA048389":"AB_2680382","HPA074166":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.41e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"}},{"Gene":"HERPUD1","Gene synonym":["HERP","KIAA0025","Mif1","SUP"],"Ensembl":"ENSG00000051108","Gene description":"Homocysteine inducible ER protein with ubiquitin like domain 1","Uniprot":["Q15011"],"Chromosome":"16","Position":"56932142-56944864","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Unfolded protein response"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"2251.5","Plasma cells":"2092.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"314.4"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037041","CAB037104","HPA040754","HPA041219"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB037041":"AB_1840910","CAB037104":"AB_1840912","HPA040754":"AB_10794068","HPA041219":"AB_10794268"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.41e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-3"}},{"Gene":"HERPUD2","Gene synonym":["FLJ22313"],"Ensembl":"ENSG00000122557","Gene description":"HERPUD family member 2","Uniprot":["Q9BSE4"],"Chromosome":"7","Position":"35632659-35697459","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Unfolded protein response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"215.3","Late spermatids":"698.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015630","HPA076087"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Nucleoli rim"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":null,"Antibody RRID":{"HPA015630":"AB_1850609","HPA076087":"AB_2686774"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"}},{"Gene":"HFE","Gene synonym":["HFE1","HLA-H"],"Ensembl":"ENSG00000010704","Gene description":"Homeostatic iron regulator","Uniprot":["Q30201"],"Chromosome":"6","Position":"26087281-26098343","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Ion transport","Iron transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017276","HPA053470"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA017276":"AB_1850677","HPA053470":"AB_2682163"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"}},{"Gene":"HGS","Gene synonym":["Hrs","Vps27","ZFYVE8"],"Ensembl":"ENSG00000185359","Gene description":"Hepatocyte growth factor-regulated tyrosine kinase substrate","Uniprot":["O14964"],"Chromosome":"17","Position":"81683326-81703138","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"149.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004872","HPA007728"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endosomes","Lysosomes","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"45000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Endosomes","Lysosomes"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA004872":"AB_1079053","HPA007728":"AB_1850681"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.22e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.61e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.31e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"}},{"Gene":"HGSNAT","Gene synonym":["FLJ32731","HGNAT","TMEM76"],"Ensembl":"ENSG00000165102","Gene description":"Heparan-alpha-glucosaminide N-acetyltransferase","Uniprot":["Q68CP4"],"Chromosome":"8","Position":"43140464-43202855","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Mucopolysaccharidosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029578"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029578":"AB_10602423"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.46e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.33e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"}},{"Gene":"HHAT","Gene synonym":["FLJ10724","GUP2","MART-2","MART2","rasp","sit","ski","Skn"],"Ensembl":"ENSG00000054392","Gene description":"Hedgehog acyltransferase","Uniprot":["Q5VTY9"],"Chromosome":"1","Position":"210328252-210676296","Protein class":["Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Acyltransferase","Developmental protein","Transferase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"25.0","dendritic cells":"27.7","Excitatory neurons":"47.0","Oligodendrocytes":"24.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"3.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"1.8","dendritic cells":"3.7","T-cells":"1.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Outer root sheath cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016462"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA016462":"AB_2669360"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.47e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"}},{"Gene":"HHATL","Gene synonym":["C3orf3","GUP1","KIAA1173","MBOAT3","MSTP002","OACT3"],"Ensembl":"ENSG00000010282","Gene description":"Hedgehog acyltransferase like","Uniprot":["Q9HCP6"],"Chromosome":"3","Position":"42692663-42702824","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"241.1","heart muscle":"521.2","skeletal muscle":"282.3","tongue":"154.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Astrocytes":"57.3","Bipolar cells":"102.7","Cardiomyocytes":"156.2","Muller glia cells":"42.3","Oligodendrocytes":"158.5","Skeletal myocytes":"63.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"14.2","thyroid cancer":"25.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"thyroid cancer":"4.4"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Lung - Respiratory ciliated cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018174"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018174":"AB_2116671"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"}},{"Gene":"HHIP","Gene synonym":["FLJ20992","HIP"],"Ensembl":"ENSG00000164161","Gene description":"Hedgehog interacting protein","Uniprot":["Q96QV1"],"Chromosome":"4","Position":"144646156-144745271","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"37.3","lung":"16.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Alveolar cells type 2":"275.5","Leydig cells":"144.8","Oligodendrocytes":"390.1","Theca cells":"130.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Rhabdoid":"111.4"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Fibroblasts","Liver - Hepatic stellate cells","Lung - Alveolar cells type 2","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012616"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA012616":"AB_1850687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"}},{"Gene":"HHLA2","Gene synonym":["B7-H5","B7-H7","B7H7","B7y"],"Ensembl":"ENSG00000114455","Gene description":"HERV-H LTR-associating 2","Uniprot":["Q9UM44"],"Chromosome":"3","Position":"108296490-108378285","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"129.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"26.9","Distal enterocytes":"134.5","Exocrine glandular cells":"42.8","Proximal enterocytes":"174.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"colorectal cancer":"9.2","lung cancer":"5.0","pancreatic cancer":"5.1","renal cancer":"16.6","stomach cancer":"6.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"1.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"10.8","Rhabdoid":"14.1"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Lung - Respiratory ciliated cells","Stomach - Gastric mucous cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055478"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055478":"AB_2682830"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"}},{"Gene":"HIGD1A","Gene synonym":["DKFZP564K247","HIG1","RCF1A"],"Ensembl":"ENSG00000181061","Gene description":"HIG1 hypoxia inducible domain family member 1A","Uniprot":["Q9Y241"],"Chromosome":"3","Position":"42782908-42804490","Protein class":["Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Stress response","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"519.8","Distal enterocytes":"629.7","Distal tubular cells":"727.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"509.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043336"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA043336":"AB_10795039"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.12e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.99e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"}},{"Gene":"HIGD1B","Gene synonym":["CLST11240","CLST11240-15"],"Ensembl":"ENSG00000131097","Gene description":"HIG1 hypoxia inducible domain family member 1B","Uniprot":["Q9P298"],"Chromosome":"17","Position":"44846353-44850476","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"114.6","choroid plexus":"65.0","placenta":"105.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"78.5","Muller glia cells":"63.1","Sertoli cells":"306.8","Smooth muscle cells":"181.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"9.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079501"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Microtubules","Cytokinetic bridge","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Microtubules","Cytokinetic bridge","Mitotic spindle"],"Subcellular additional location":null,"Antibody RRID":{"HPA079501":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"}},{"Gene":"HIGD1C","Gene synonym":["Gm921"],"Ensembl":"ENSG00000214511","Gene description":"HIG1 hypoxia inducible domain family member 1C","Uniprot":["A8MV81"],"Chromosome":"12","Position":"50953922-50970506","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"6.0","Early spermatids":"8.7","Excitatory neurons":"3.3","Inhibitory neurons":"3.9","Oligodendrocyte precursor cells":"6.7","Oligodendrocytes":"4.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"10","RNA mouse brain regional specific nTPM":{"hypothalamus":"1.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"HIGD2A","Gene synonym":["MGC2198","RCF1B"],"Ensembl":"ENSG00000146066","Gene description":"HIG1 hypoxia inducible domain family member 2A","Uniprot":["Q9BW72"],"Chromosome":"5","Position":"176388751-176389761","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042715"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA042715":"AB_2678127"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"}},{"Gene":"HIGD2B","Gene synonym":["HIGD2BP"],"Ensembl":"ENSG00000175202","Gene description":"HIG1 hypoxia inducible domain family member 2B","Uniprot":["Q4VC39"],"Chromosome":"15","Position":"72675798-72686182","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"testis":"3.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Early spermatids":"20.6","Late spermatids":"9.3","Spermatocytes":"17.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019016","HPA042715"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA019016":"AB_1850711","HPA042715":"AB_2678127"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"}},{"Gene":"HILPDA","Gene synonym":["C7orf68","FLJ21076","HIG-2","HIG2"],"Ensembl":"ENSG00000135245","Gene description":"Hypoxia inducible lipid droplet associated","Uniprot":["Q9Y5L2"],"Chromosome":"7","Position":"128455849-128458418","Protein class":["Predicted membrane proteins"],"Biological process":["Stress response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"164.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"169.2","Extravillous trophoblasts":"288.2","Ionocytes":"182.8","Syncytiotrophoblasts":"331.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"72.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"67.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010515"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Lipid droplets"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Lipid droplets"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA010515":"AB_1850710"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.30e-11"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.05e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"}},{"Gene":"HIPK1","Gene synonym":["KIAA0630","MGC26642","MGC33446","MGC33548","Myak","Nbak2"],"Ensembl":"ENSG00000163349","Gene description":"Homeodomain interacting protein kinase 1","Uniprot":["Q86Z02"],"Chromosome":"1","Position":"113929324-113977869","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"142.0"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016664"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA016664":"AB_1850725"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"}},{"Gene":"HJV","Gene synonym":["haemojuvelin","hemojuvelin","HFE2","HFE2A","JH","RGMC"],"Ensembl":"ENSG00000168509","Gene description":"Hemojuvelin BMP co-receptor","Uniprot":["Q6ZVN8"],"Chromosome":"1","Position":"146017468-146036746","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"239.6","skeletal muscle":"591.1","tongue":"291.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Cardiomyocytes":"61.7","Hepatocytes":"179.1","Skeletal myocytes":"76.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"96","RNA cancer specific FPKM":{"liver cancer":"87.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"1.3","liver cancer":"1.0","Sarcoma":"1.1"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"69000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"}},{"Gene":"HK3","Gene synonym":[],"Ensembl":"ENSG00000160883","Gene description":"Hexokinase 3","Uniprot":["P52790"],"Chromosome":"5","Position":"176880869-176899346","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Allosteric enzyme","Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"129.3","lymphoid tissue":"76.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Early spermatids":"14.1","Hofbauer cells":"36.9","Kupffer cells":"37.9","Macrophages":"32.7","monocytes":"45.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"cerebellum":"1.4","cerebral cortex":"1.6","thalamus":"2.4"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"569.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"569.7","monocytes":"200.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"3.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Kidney - Macrophages","Lung - Neutrophil_2","Prostate - Macrophages","Skin - Macrophages","Stomach - Macrophages","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056743"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056743":"AB_2683222"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.84e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"}},{"Gene":"HLA-A","Gene synonym":[],"Ensembl":"ENSG00000206503","Gene description":"Major histocompatibility complex, class I, A","Uniprot":["P04439"],"Chromosome":"6","Position":"29941260-29945884","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"3575.6","NK-cells":"3270.5","Proximal enterocytes":"5332.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB078470"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB078470":"AB_10985125"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.59e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.47e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"HLA-B","Gene synonym":["AS"],"Ensembl":"ENSG00000234745","Gene description":"Major histocompatibility complex, class I, B","Uniprot":["P01889"],"Chromosome":"6","Position":"31353872-31357188","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"2493.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"5197.8","Proximal enterocytes":"4389.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015418"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015418":"AB_831547"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"}},{"Gene":"HLA-C","Gene synonym":["D6S204","HLA-JY3","PSORS1"],"Ensembl":"ENSG00000204525","Gene description":"Major histocompatibility complex, class I, C","Uniprot":["P10321"],"Chromosome":"6","Position":"31268749-31272130","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"1445.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"2944.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"}},{"Gene":"HLA-DMA","Gene synonym":["D6S222E","RING6"],"Ensembl":"ENSG00000204257","Gene description":"Major histocompatibility complex, class II, DM alpha","Uniprot":["P28067"],"Chromosome":"6","Position":"32948613-32969094","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"120.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"413.8","dendritic cells":"491.7","Hofbauer cells":"452.7","Langerhans cells":"1635.9","Macrophages":"567.8","monocytes":"400.1","Schwann cells":"452.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"3.8","intermediate monocyte":"3.8","memory B-cell":"6.3","myeloid DC":"7.2","naive B-cell":"6.4","plasmacytoid DC":"5.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"B-cells":"6.4","dendritic cells":"7.2","monocytes":"3.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"18.9"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012750","HPA017295"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA012750":"AB_1853926","HPA017295":"AB_2669575"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.64e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.59e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"}},{"Gene":"HLA-DMB","Gene synonym":["D6S221E","RING7"],"Ensembl":"ENSG00000242574","Gene description":"Major histocompatibility complex, class II, DM beta","Uniprot":["P28068"],"Chromosome":"6","Position":"32934629-32941028","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"78.8","lymphoid tissue":"101.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"245.4","dendritic cells":"311.4","Hofbauer cells":"317.2","Langerhans cells":"582.6","Macrophages":"259.7","monocytes":"224.8","Proximal enterocytes":"283.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"128.8","dendritic cells":"85.3","monocytes":"73.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"18.7","prostate cancer":"12.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Heart muscle - T-cells","Lung - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012298","HPA077524"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA012298":"AB_1853927","HPA077524":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.89e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"}},{"Gene":"HLA-DOA","Gene synonym":["HLA-D0-alpha","HLA-DNA","HLA-DZA"],"Ensembl":"ENSG00000204252","Gene description":"Major histocompatibility complex, class II, DO alpha","Uniprot":["P06340"],"Chromosome":"6","Position":"33004182-33009591","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"28.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"63.7","dendritic cells":"54.8","Langerhans cells":"77.9","Macrophages":"40.5","monocytes":"27.4","Schwann cells":"25.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"17.8","naive B-cell":"21.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"B-cells":"21.0","dendritic cells":"17.8","monocytes":"6.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"lymphoma":"15.1"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Heart muscle - T-cells","Prostate - T-cells","Testis - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045038","HPA076922"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045038":"AB_10959457","HPA076922":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"}},{"Gene":"HLA-DOB","Gene synonym":[],"Ensembl":"ENSG00000241106","Gene description":"Major histocompatibility complex, class II, DO beta","Uniprot":["P13765"],"Chromosome":"6","Position":"32812763-32820466","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"19.5","lymphoid tissue":"41.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"95.6","Langerhans cells":"26.5","Plasma cells":"28.0","Schwann cells":"54.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"18","RNA blood cell specific nTPM":{"memory B-cell":"213.8","naive B-cell":"258.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"B-cells":"258.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"lymphoma":"18.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013846"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013846":"AB_1853928"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.29e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.17e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"}},{"Gene":"HLA-DPA1","Gene synonym":["HLA-DP1A"],"Ensembl":"ENSG00000231389","Gene description":"Major histocompatibility complex, class II, DP alpha 1","Uniprot":["P20036"],"Chromosome":"6","Position":"33064569-33080775","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"319.9","lymphoid tissue":"359.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"2170.0","dendritic cells":"1561.4","Langerhans cells":"9073.4","Macrophages":"2629.4","monocytes":"2665.0","Schwann cells":"6187.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"81.8","intermediate monocyte":"187.4","memory B-cell":"150.4","myeloid DC":"296.0","naive B-cell":"136.5","non-classical monocyte":"124.1","plasmacytoid DC":"82.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"150.4","dendritic cells":"296.0","monocytes":"187.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"45.7","Myeloma":"26.9","skin cancer":"26.4"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Testis - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017967"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA017967":"AB_1853929"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"HLA-DPB1","Gene synonym":["HLA-DP1B"],"Ensembl":"ENSG00000223865","Gene description":"Major histocompatibility complex, class II, DP beta 1","Uniprot":["P04440"],"Chromosome":"6","Position":"33075990-33089696","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"278.7","lymphoid tissue":"409.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"2809.3","Langerhans cells":"13791.8","Macrophages":"2387.3","monocytes":"2973.7","Schwann cells":"5787.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"285.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"B-cells":"227.8","dendritic cells":"285.5","monocytes":"137.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"14.5"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Testis - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011078","HPA058509"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"470000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA011078":"AB_1079378","HPA058509":"AB_2683737"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.38e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"}},{"Gene":"HLA-DQA1","Gene synonym":["CELIAC1","HLA-DQA"],"Ensembl":"ENSG00000196735","Gene description":"Major histocompatibility complex, class II, DQ alpha 1","Uniprot":["P01909"],"Chromosome":"6","Position":"32628179-32647062","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"333.9","lymphoid tissue":"335.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1057.6","dendritic cells":"636.6","Langerhans cells":"4572.6","Macrophages":"816.7","monocytes":"718.9","Schwann cells":"1888.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"666.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"B-cells":"287.6","dendritic cells":"666.6","monocytes":"257.6"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"lymphoma":"178.0"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Heart muscle - T-cells","Skin - Langerhans cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012315"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012315":"AB_1853930"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"}},{"Gene":"HLA-DQA2","Gene synonym":["HLA-DXA"],"Ensembl":"ENSG00000237541","Gene description":"Major histocompatibility complex, class II, DQ alpha 2","Uniprot":["P01906"],"Chromosome":"6","Position":"32741391-32747198","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"20.8","lymphoid tissue":"27.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"192.0","dendritic cells":"343.9","Langerhans cells":"695.6","Macrophages":"229.1","monocytes":"324.2","Schwann cells":"390.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Langerhans cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"}},{"Gene":"HLA-DQB1","Gene synonym":["CELIAC1","HLA-DQB","IDDM1"],"Ensembl":"ENSG00000179344","Gene description":"Major histocompatibility complex, class II, DQ beta 1","Uniprot":[],"Chromosome":"6","Position":"32659467-32668383","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"179.1","lymphoid tissue":"301.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1210.3","dendritic cells":"889.1","Langerhans cells":"5029.0","Macrophages":"1059.2","monocytes":"889.8","Schwann cells":"2162.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"153.5","intermediate monocyte":"142.9","memory B-cell":"159.2","myeloid DC":"386.3","naive B-cell":"169.1","plasmacytoid DC":"116.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"169.1","dendritic cells":"386.3","monocytes":"153.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"85.7"},"RNA tissue cell type enrichment":["Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013667"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Rods & Rings"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA013667":"AB_1853932"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"}},{"Gene":"HLA-DQB2","Gene synonym":["HLA-DXB"],"Ensembl":"ENSG00000232629","Gene description":"Major histocompatibility complex, class II, DQ beta 2","Uniprot":["P05538"],"Chromosome":"6","Position":"32756098-32763532","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"52.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Langerhans cells":"188.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073187"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA073187":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.55e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"}},{"Gene":"HLA-DRA","Gene synonym":["HLA-DRA1"],"Ensembl":"ENSG00000204287","Gene description":"Major histocompatibility complex, class II, DR alpha","Uniprot":["P01903"],"Chromosome":"6","Position":"32439878-32445046","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"940.2","lymphoid tissue":"1277.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"6160.8","Langerhans cells":"29244.1","Macrophages":"6284.3","monocytes":"6002.6","Schwann cells":"10365.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"36.2"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"209.3","intermediate monocyte":"408.8","memory B-cell":"379.6","naive B-cell":"418.5","non-classical monocyte":"255.2","plasmacytoid DC":"229.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"418.5","dendritic cells":"229.8","monocytes":"408.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"Leukemia":"101.9","lymphoma":"289.5","Myeloma":"123.5","skin cancer":"82.3"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Stomach - Macrophages","Testis - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002798","CAB015402","HPA050162","HPA053176"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"950000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002798":null,"CAB015402":"AB_629980","HPA050162":"AB_2681037","HPA053176":"AB_2682070"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.30e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"}},{"Gene":"HLA-DRB1","Gene synonym":["HLA-DR1B"],"Ensembl":"ENSG00000196126","Gene description":"Major histocompatibility complex, class II, DR beta 1","Uniprot":["P01911"],"Chromosome":"6","Position":"32578769-32589848","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"581.3","lymphoid tissue":"651.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"2399.6","Langerhans cells":"11552.1","Macrophages":"2931.0","monocytes":"2017.7","Schwann cells":"5003.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"47.5"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"749.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"257.9","dendritic cells":"749.2","monocytes":"371.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"170.1","skin cancer":"85.7"},"RNA tissue cell type enrichment":["Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015400","CAB034021","HPA043151"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015400":"AB_784538","CAB034021":"AB_1124844","HPA043151":"AB_2678342"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"}},{"Gene":"HLA-DRB5","Gene synonym":[],"Ensembl":"ENSG00000198502","Gene description":"Major histocompatibility complex, class II, DR beta 5","Uniprot":["Q30154"],"Chromosome":"6","Position":"32517353-32530287","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"356.2","lymphoid tissue":"423.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"678.2","Langerhans cells":"2086.2","Macrophages":"795.0","Proximal enterocytes":"717.9","Schwann cells":"1323.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"61.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"B-cells":"26.1","dendritic cells":"61.9","monocytes":"35.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"118.0","skin cancer":"41.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043151"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043151":"AB_2678342"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.89e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"}},{"Gene":"HLA-E","Gene synonym":[],"Ensembl":"ENSG00000204592","Gene description":"Major histocompatibility complex, class I, E","Uniprot":["P13747"],"Chromosome":"6","Position":"30489509-30494194","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"2307.0","Endothelial cells":"1450.2","monocytes":"1690.8","NK-cells":"1859.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"109.5"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Skeletal muscle - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB024589","HPA031454"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB024589":"AB_324025","HPA031454":"AB_2673891"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.86e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"}},{"Gene":"HLA-F","Gene synonym":[],"Ensembl":"ENSG00000204642","Gene description":"Major histocompatibility complex, class I, F","Uniprot":["P30511"],"Chromosome":"6","Position":"29722775-29738528","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"188.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"207.9","NK-cells":"382.8","Proximal enterocytes":"325.6","T-cells":"191.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Lung - NK-cells (Lung)","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.67e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"}},{"Gene":"HLA-G","Gene synonym":[],"Ensembl":"ENSG00000204632","Gene description":"Major histocompatibility complex, class I, G","Uniprot":["P17693"],"Chromosome":"6","Position":"29826967-29831125","Protein class":["Cancer-related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"pituitary gland":"13.8","placenta":"11.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"2193.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"1.5"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016158"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":32800000,"Blood concentration - Conc. blood MS [pg\/L]":"67000000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016158":"AB_627938"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.91e-5"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"}},{"Gene":"HM13","Gene synonym":["dJ324O17.1","H13","IMP1","IMPAS","PSENL3","PSL3","SPP","SPPL1"],"Ensembl":"ENSG00000101294","Gene description":"Histocompatibility minor 13","Uniprot":["Q8TCT9"],"Chromosome":"20","Position":"31514410-31577923","Protein class":["Enzymes","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"443.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045089","HPA056062"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA045089":"AB_10962054","HPA056062":"AB_2683022"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.95e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"}},{"Gene":"HMGCR","Gene synonym":[],"Ensembl":"ENSG00000113161","Gene description":"3-hydroxy-3-methylglutaryl-CoA reductase","Uniprot":["P04035"],"Chromosome":"5","Position":"75336329-75364001","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"105.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"236.4","Suprabasal keratinocytes":"131.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008338","CAB016797","CAB078688"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016797":null,"CAB078688":"AB_2665607","HPA008338":"AB_10960401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.42e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"}},{"Gene":"HMOX1","Gene synonym":["bK286B10","HO-1"],"Ensembl":"ENSG00000100292","Gene description":"Heme oxygenase 1","Uniprot":["P09601"],"Chromosome":"22","Position":"35380361-35394214","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"612.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"315.8","Hofbauer cells":"514.0","Kupffer cells":"245.0","Macrophages":"496.0","Syncytiotrophoblasts":"650.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"98.8","intermediate monocyte":"238.8","non-classical monocyte":"329.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"monocytes":"329.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Proximal tubular cells","Prostate - Macrophages","Skin - Keratinocyte (granular)","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000635","CAB017444"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB017444":"AB_10617276","HPA000635":"AB_1079089"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"}},{"Gene":"HMOX2","Gene synonym":["HO-2"],"Ensembl":"ENSG00000103415","Gene description":"Heme oxygenase 2","Uniprot":["P30519"],"Chromosome":"16","Position":"4474690-4510347","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"2044.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025464","HPA040611"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB025464":null,"HPA040611":"AB_10961034"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.91e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.98e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"}},{"Gene":"HOGA1","Gene synonym":["C10orf65","DHDPS2","DHDPSL","FLJ37472","NPL2"],"Ensembl":"ENSG00000241935","Gene description":"4-hydroxy-2-oxoglutarate aldolase 1","Uniprot":["Q86XE5"],"Chromosome":"10","Position":"97584323-97612802","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"51.8","liver":"54.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"28.9","Distal tubular cells":"28.0","Hepatocytes":"42.5","Late spermatids":"19.2","Proximal tubular cells":"100.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"4.5","renal cancer":"9.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Kidney cancer":"31.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039466"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039466":"AB_2676522"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-4"}},{"Gene":"HOOK2","Gene synonym":["HK2"],"Ensembl":"ENSG00000095066","Gene description":"Hook microtubule tethering protein 2","Uniprot":["Q96ED9"],"Chromosome":"19","Position":"12763003-12872740","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ionocytes":"258.8","Proximal enterocytes":"273.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043519","HPA050351"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043519":"AB_2678525","HPA050351":"AB_2681102"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.59e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.28e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"}},{"Gene":"HORMAD1","Gene synonym":["CT46","DKFZP434A1315"],"Ensembl":"ENSG00000143452","Gene description":"HORMA domain containing 1","Uniprot":["Q86X24"],"Chromosome":"1","Position":"150698060-150720895","Protein class":["Predicted intracellular proteins"],"Biological process":["Differentiation","Meiosis","Oogenesis","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"testis":"117.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Spermatocytes":"724.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"6.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"17.7"},"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028346","HPA037850"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA028346":"AB_2672564","HPA037850":"AB_10696358"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"}},{"Gene":"HORMAD2","Gene synonym":["CT46.2","MGC26710"],"Ensembl":"ENSG00000176635","Gene description":"HORMA domain containing 2","Uniprot":["Q8N7B1"],"Chromosome":"22","Position":"30080464-30177075","Protein class":["Predicted intracellular proteins"],"Biological process":["Meiosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"testis":"22.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Early spermatids":"68.7","Spermatocytes":"120.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003074","HPA043880"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"HPA003074":"AB_1850916","HPA043880":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"HOXC11","Gene synonym":["HOX3H"],"Ensembl":"ENSG00000123388","Gene description":"Homeobox C11","Uniprot":["O43248"],"Chromosome":"12","Position":"53973126-53977643","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"1.8","skin 1":"5.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"4.2","Langerhans cells":"1.4","Proximal enterocytes":"3.5","Spermatocytes":"3.4","Suprabasal keratinocytes":"2.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"17.2"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells (progenitors)","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"13","RNA pig brain regional specific nTPM":{"spinal cord":"1.3"},"Antibody":["HPA038291"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA038291":"AB_10674552"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"}},{"Gene":"HPN","Gene synonym":["TMPRSS1"],"Ensembl":"ENSG00000105707","Gene description":"Hepsin","Uniprot":["P05981"],"Chromosome":"19","Position":"35040506-35066573","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"200.5","liver":"866.2","pancreas":"272.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatocytes":"378.7","Proximal tubular cells":"164.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"127.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"liver cancer":"21.4","prostate cancer":"58.4"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Kidney - Proximal tubular cells","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006804"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA006804":"AB_1079046"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"}},{"Gene":"HPS6","Gene synonym":["BLOC2S3","FLJ22501"],"Ensembl":"ENSG00000166189","Gene description":"HPS6 biogenesis of lysosomal organelles complex 2 subunit 3","Uniprot":["Q86YV9"],"Chromosome":"10","Position":"102065349-102068036","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Albinism","Hermansky-Pudlak syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040687"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040687":"AB_2677078"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"}},{"Gene":"HRCT1","Gene synonym":["LGLL338","PRO537","UNQ338"],"Ensembl":"ENSG00000196196","Gene description":"Histidine rich carboxyl terminus 1","Uniprot":["Q6UXD1"],"Chromosome":"9","Position":"35906202-35907136","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"29.4","breast":"24.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"79.5","Distal enterocytes":"206.0","Intestinal goblet cells":"48.5","Paneth cells":"248.5","Proximal enterocytes":"68.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"23.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067038"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA067038":"AB_2685767"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"}},{"Gene":"HRH1","Gene synonym":[],"Ensembl":"ENSG00000196639","Gene description":"Histamine receptor H1","Uniprot":["P35367"],"Chromosome":"3","Position":"11137093-11263557","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"32.3","Excitatory neurons":"34.1","Glandular and luminal cells":"39.7","Granulosa cells":"28.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Kupffer cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029740"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA029740":"AB_10601578"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.27e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"}},{"Gene":"HRH2","Gene synonym":[],"Ensembl":"ENSG00000113749","Gene description":"Histamine receptor H2","Uniprot":["P25021"],"Chromosome":"5","Position":"175658030-175710756","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"37.0","heart muscle":"26.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"43.4","Excitatory neurons":"61.3","Hofbauer cells":"29.2","Kupffer cells":"52.5","Macrophages":"43.8","monocytes":"48.8","Smooth muscle cells":"32.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"melanoma":"2.9","renal cancer":"4.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"134.4","neutrophil":"161.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"161.7","monocytes":"51.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"9.4","Myeloma":"4.9"},"RNA tissue cell type enrichment":["Liver - Neutrophils","Lung - Neutrophil_2","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013770"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013770":"AB_1851086"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"}},{"Gene":"HRH3","Gene synonym":["GPCR97"],"Ensembl":"ENSG00000101180","Gene description":"Histamine receptor H3","Uniprot":["Q9Y5N1"],"Chromosome":"20","Position":"62214960-62220278","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"brain":"59.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Horizontal cells":"16.0","Inhibitory neurons":"23.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"8.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"}},{"Gene":"HRH4","Gene synonym":["AXOR35","GPCR105","GPRv53","H4R","HH4R"],"Ensembl":"ENSG00000134489","Gene description":"Histamine receptor H4","Uniprot":["Q9H3N8"],"Chromosome":"18","Position":"24460637-24479961","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1.3","granulocytes":"5.1","Langerhans cells":"1.1","Melanocytes":"1.7","Spermatocytes":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"123","RNA blood cell specific nTPM":{"basophil":"212.9","eosinophil":"61.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"191","RNA blood lineage specific nTPM":{"granulocytes":"212.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Mast cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035009"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035009":"AB_10671507"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"}},{"Gene":"HRK","Gene synonym":["DP5"],"Ensembl":"ENSG00000135116","Gene description":"Harakiri, BCL2 interacting protein","Uniprot":["O00198"],"Chromosome":"12","Position":"116856144-116881441","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.4","choroid plexus":"4.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"8.6","Endometrial ciliated cells":"11.5","Excitatory neurons":"9.4","Late spermatids":"8.2","Paneth cells":"8.0","Respiratory ciliated cells":"8.6","Sertoli cells":"13.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"2.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"30","RNA blood cell specific nTPM":{"eosinophil":"1.3","memory B-cell":"3.6","naive B-cell":"3.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"27","RNA blood lineage specific nTPM":{"B-cells":"3.9","granulocytes":"1.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"6.6"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025973"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025973":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"}},{"Gene":"HS3ST2","Gene synonym":["3OST2"],"Ensembl":"ENSG00000122254","Gene description":"Heparan sulfate-glucosamine 3-sulfotransferase 2","Uniprot":["Q9Y278"],"Chromosome":"16","Position":"22814162-22916338","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"29.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"98.4","Inhibitory neurons":"25.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Bone cancer":"4.3","Neuroblastoma":"2.5","thyroid cancer":"1.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017736"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017736":"AB_1851095"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.57e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"}},{"Gene":"HS3ST3A1","Gene synonym":["30ST3A1","3OST3A1"],"Ensembl":"ENSG00000153976","Gene description":"Heparan sulfate-glucosamine 3-sulfotransferase 3A1","Uniprot":["Q9Y663"],"Chromosome":"17","Position":"13494032-13601929","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"8.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"9.5","Fibroblasts":"7.3","Granulosa cells":"18.2","Horizontal cells":"19.9","Leydig cells":"17.2","Pancreatic endocrine cells":"8.6","Squamous epithelial cells":"11.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"medulla oblongata":"5.9"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"2.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"1.7","T-cells":"2.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"5.0"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"olfactory bulb":"5.3"},"Antibody":["HPA062518","HPA071530"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA062518":"AB_2684789","HPA071530":"AB_2686411"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-3"}},{"Gene":"HS3ST3B1","Gene synonym":["30ST3B1","3OST3B1"],"Ensembl":"ENSG00000125430","Gene description":"Heparan sulfate-glucosamine 3-sulfotransferase 3B1","Uniprot":["Q9Y662"],"Chromosome":"17","Position":"14301081-14349404","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"28.4","retina":"11.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"34.5","dendritic cells":"59.2","Hepatocytes":"36.6","Syncytiotrophoblasts":"39.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"5.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"35.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"35.1","T-cells":"26.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064126"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA064126":"AB_2685194"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"}},{"Gene":"HS6ST2","Gene synonym":[],"Ensembl":"ENSG00000171004","Gene description":"Heparan sulfate 6-O-sulfotransferase 2","Uniprot":["Q96MM7"],"Chromosome":"X","Position":"132626016-132961395","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"22.5","kidney":"13.9","ovary":"14.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"34.2","Excitatory neurons":"37.0","Inhibitory neurons":"43.3","Leydig cells":"61.9","Oligodendrocyte precursor cells":"52.0","Peritubular cells":"34.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034625"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA034625":"AB_10612119"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.03e-4"}},{"Gene":"HS6ST3","Gene synonym":[],"Ensembl":"ENSG00000185352","Gene description":"Heparan sulfate 6-O-sulfotransferase 3","Uniprot":["Q8IZP7"],"Chromosome":"13","Position":"96090107-96839562","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"12.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"27","RNA single cell type specific nTPM":{"Excitatory neurons":"1291.8","Inhibitory neurons":"875.9","Oligodendrocyte precursor cells":"927.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"1.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"2.1","Neuroblastoma":"3.1"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078257"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Plasma membrane","Actin filaments"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":["Plasma membrane","Actin filaments"],"Antibody RRID":{"HPA078257":"AB_2732374"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"}},{"Gene":"HSD11B1","Gene synonym":["HSD11","HSD11B","SDR26C1"],"Ensembl":"ENSG00000117594","Gene description":"Hydroxysteroid 11-beta dehydrogenase 1","Uniprot":["P28845"],"Chromosome":"1","Position":"209686178-209734949","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Steroid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"liver":"968.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Hepatocytes":"637.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"28","RNA cancer specific FPKM":{"liver cancer":"197.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory CD4 T-cell":"5.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"T-cells":"5.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Esophageal cancer":"19.5"},"RNA tissue cell type enrichment":["Colon - Fibroblasts","Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047729"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047729":"AB_2680135"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.97e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"}},{"Gene":"HSD11B1L","Gene synonym":["HSD1L","SCDR10","SDR26C2"],"Ensembl":"ENSG00000167733","Gene description":"Hydroxysteroid 11-beta dehydrogenase 1 like","Uniprot":["Q7Z5J1"],"Chromosome":"19","Position":"5680604-5688523","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"58.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049078"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049078":"AB_2680622"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.38e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"}},{"Gene":"HSD11B2","Gene synonym":["SDR9C3"],"Ensembl":"ENSG00000176387","Gene description":"Hydroxysteroid 11-beta dehydrogenase 2","Uniprot":["P80365"],"Chromosome":"16","Position":"67430652-67437553","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Steroid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"249.9","kidney":"335.2","salivary gland":"260.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"141.8","Distal enterocytes":"585.7","Enteroendocrine cells":"135.1","Intestinal goblet cells":"249.2","Paneth cells":"276.6","Proximal enterocytes":"251.6","Syncytiotrophoblasts":"167.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"62.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"14.2","prostate cancer":"13.7"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Intercalated cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032443","HPA042186","HPA056385"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB032443":"AB_2233199","HPA042186":"AB_2677888","HPA056385":"AB_2683110"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.51e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"}},{"Gene":"HSD17B12","Gene synonym":["KAR","SDR12C1"],"Ensembl":"ENSG00000149084","Gene description":"Hydroxysteroid 17-beta dehydrogenase 12","Uniprot":["Q53GQ0"],"Chromosome":"11","Position":"43680680-43856617","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016427"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016427":"AB_1844347"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.76e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.10e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"}},{"Gene":"HSD17B2","Gene synonym":["HSD17","SDR9C2"],"Ensembl":"ENSG00000086696","Gene description":"Hydroxysteroid 17-beta dehydrogenase 2","Uniprot":["P37059"],"Chromosome":"16","Position":"82035004-82098534","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"429.0","liver":"217.9","placenta":"381.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"150.1","Distal enterocytes":"147.5","Hepatocytes":"121.9","Paneth cells":"205.6","Proximal enterocytes":"405.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"10.9","pancreatic cancer":"6.5","stomach cancer":"4.2","urothelial cancer":"5.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"33.8"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"midbrain":"2.2","pons and medulla":"3.4"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021826","HPA050235"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA021826":"AB_10961148","HPA050235":"AB_2681059"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.83e-4"}},{"Gene":"HSD17B6","Gene synonym":["HSE","RODH","SDR9C6"],"Ensembl":"ENSG00000025423","Gene description":"Hydroxysteroid 17-beta dehydrogenase 6","Uniprot":["O14756"],"Chromosome":"12","Position":"56752161-56787790","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Steroid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"26","RNA tissue specific nTPM":{"liver":"1804.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Hepatocytes":"1769.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"170.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Mesothelial cells","Kidney - Fibroblasts","Liver - Hepatocytes","Liver - Hepatocytes","Skin - Smooth muscle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059141"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059141":"AB_2683922"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.32e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"HSD17B7","Gene synonym":["PRAP","SDR37C1"],"Ensembl":"ENSG00000132196","Gene description":"Hydroxysteroid 17-beta dehydrogenase 7","Uniprot":["P56937"],"Chromosome":"1","Position":"162790702-162812817","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"30.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"52.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047496"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047496":"AB_2680068"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.47e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"}},{"Gene":"HSD3B2","Gene synonym":["SDR11E2"],"Ensembl":"ENSG00000203859","Gene description":"Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2","Uniprot":["P26439"],"Chromosome":"1","Position":"119414931-119423035","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Steroidogenesis"],"Molecular function":["Isomerase","Multifunctional enzyme","Oxidoreductase"],"Disease involvement":["Congenital adrenal hyperplasia","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"56","RNA tissue specific nTPM":{"adrenal gland":"2174.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Granulosa cells":"42.7","Proximal enterocytes":"52.4","Theca cells":"55.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"20","RNA cell line specific nTPM":{"skin cancer":"10.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043261","HPA043264","HPA044028"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Endoplasmic reticulum","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoli","Endoplasmic reticulum"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA043261":"AB_2630368","HPA043264":"AB_2678398","HPA044028":"AB_2678781"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"HSD3B7","Gene synonym":["C(27)-3BETA-HSD","SDR11E3"],"Ensembl":"ENSG00000099377","Gene description":"Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7","Uniprot":["Q9H2F3"],"Chromosome":"16","Position":"30985207-30989147","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Steroidogenesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Intrahepatic cholestasis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"136.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"38.9","Hepatocytes":"58.3","Hofbauer cells":"48.8","Proximal enterocytes":"45.5","Proximal tubular cells":"43.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"27","RNA blood cell specific nTPM":{"basophil":"61.8","eosinophil":"27.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"38","RNA blood lineage specific nTPM":{"granulocytes":"61.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Testis - Late spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015965","HPA050521","HPA060847"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"HPA015965":null,"HPA050521":"AB_2681155","HPA060847":"AB_2684379"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.95e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"HSDL1","Gene synonym":["SDR12C3"],"Ensembl":"ENSG00000103160","Gene description":"Hydroxysteroid dehydrogenase like 1","Uniprot":["Q3SXM5"],"Chromosome":"16","Position":"84122141-84145192","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045745"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Intermediate filaments","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Vesicles","Intermediate filaments"],"Antibody RRID":{"HPA045745":"AB_2679440"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.20e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"}},{"Gene":"HSF5","Gene synonym":["FLJ40311"],"Ensembl":"ENSG00000176160","Gene description":"Heat shock transcription factor 5","Uniprot":["Q4G112"],"Chromosome":"17","Position":"58420167-58488408","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"41","RNA tissue specific nTPM":{"testis":"48.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"64.2","Spermatocytes":"56.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"1.3","T-cells":"1.1"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016440","HPA063613"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA016440":"AB_1851142","HPA063613":"AB_2685060"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"}},{"Gene":"HSPA12A","Gene synonym":["FLJ13874","KIAA0417"],"Ensembl":"ENSG00000165868","Gene description":"Heat shock protein family A (Hsp70) member 12A","Uniprot":["O43301"],"Chromosome":"10","Position":"116671192-116850251","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"202.1","Horizontal cells":"97.4","Inhibitory neurons":"182.3","Schwann cells":"110.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"memory B-cell":"1.3","naive B-cell":"1.7","T-reg":"1.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"B-cells":"1.7","T-cells":"1.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011273","HPA073244"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA011273":"AB_1851190","HPA073244":"AB_2686586"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.61e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-4"}},{"Gene":"HSPA13","Gene synonym":["STCH"],"Ensembl":"ENSG00000155304","Gene description":"Heat shock protein family A (Hsp70) member 13","Uniprot":["P48723"],"Chromosome":"21","Position":"14371115-14383484","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"115.5","Syncytiotrophoblasts":"76.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014797"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014797":"AB_1857567"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"}},{"Gene":"HSPB8","Gene synonym":["CMT2L","E2IG1","H11","HSP22"],"Ensembl":"ENSG00000152137","Gene description":"Heat shock protein family B (small) member 8","Uniprot":["Q9UJY1"],"Chromosome":"12","Position":"119171555-119224855","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Stress response"],"Molecular function":["Chaperone"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"897.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"530.6","Skeletal myocytes":"303.9","Syncytiotrophoblasts":"1686.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Pancreas - Ductal cells","Prostate - Smooth muscle cells","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015876"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA015876":"AB_1850458"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.98e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"}},{"Gene":"HTATIP2","Gene synonym":["CC3","FLJ26963","SDR44U1","TIP30"],"Ensembl":"ENSG00000109854","Gene description":"HIV-1 Tat interactive protein 2","Uniprot":["Q9BUP3"],"Chromosome":"11","Position":"20363685-20383782","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Apoptosis","Differentiation","Host-virus interaction"],"Molecular function":["Developmental protein","Oxidoreductase"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"267.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006417","HPA024321"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA006417":"AB_1079091","HPA024321":"AB_1851288"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"}},{"Gene":"HTR1A","Gene synonym":["5-HT1A","ADRB2RL1","ADRBRL1"],"Ensembl":"ENSG00000178394","Gene description":"5-hydroxytryptamine receptor 1A","Uniprot":["P08908"],"Chromosome":"5","Position":"63957874-63962507","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Behavior"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"24.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Leydig cells":"6.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"24.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"Rhabdoid":"7.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018073"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018073":"AB_1856704"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"HTR1B","Gene synonym":["5-HT1B","5-HT1DB","HTR1D2","S12"],"Ensembl":"ENSG00000135312","Gene description":"5-hydroxytryptamine receptor 1B","Uniprot":["P28222"],"Chromosome":"6","Position":"77460924-77463491","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Behavior"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"9.6","placenta":"6.7","stomach 1":"5.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"1.9","Smooth muscle cells":"1.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"pancreatic cancer":"0.7","stomach cancer":"0.8","testis cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Lung - Smooth muscle cells","Skeletal muscle - Smooth muscle cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"38.6"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"11.7"},"Antibody":["HPA028808"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Endoplasmic reticulum","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA028808":"AB_2672782"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"HTR1D","Gene synonym":["5-HT1D","HT1DA","HTRL","RDC4"],"Ensembl":"ENSG00000179546","Gene description":"5-hydroxytryptamine receptor 1D","Uniprot":["P28221"],"Chromosome":"1","Position":"23191895-23194729","Protein class":["FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"12.4","intestine":"9.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cholangiocytes":"5.8","Proximal enterocytes":"7.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"12.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Ductal cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.30e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-3"}},{"Gene":"HTR1E","Gene synonym":["5-HT1E"],"Ensembl":"ENSG00000168830","Gene description":"5-hydroxytryptamine receptor 1E","Uniprot":["P28566"],"Chromosome":"6","Position":"86937528-87016679","Protein class":["FDA approved drug targets","G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.2","ovary":"4.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Excitatory neurons":"123.5","Inhibitory neurons":"101.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"1.7"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Stomach - Chief cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004931"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004931":"AB_1856706"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"HTR1F","Gene synonym":["5-HT1F","HTR1EL"],"Ensembl":"ENSG00000179097","Gene description":"5-hydroxytryptamine receptor 1F","Uniprot":["P30939"],"Chromosome":"3","Position":"87792706-87993839","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"1.8","retina":"3.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"229.1","Inhibitory neurons":"76.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"1.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"1.4","Leukemia":"1.2","thyroid cancer":"1.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005555"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA005555":"AB_1856708"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"}},{"Gene":"HTR2A","Gene synonym":["5-HT2A","HTR2"],"Ensembl":"ENSG00000102468","Gene description":"5-hydroxytryptamine receptor 2A","Uniprot":["P28223"],"Chromosome":"13","Position":"46831546-46897076","Protein class":["FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":["Behavior","Host-virus interaction"],"Molecular function":["G-protein coupled receptor","Host cell receptor for virus entry","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"15.2","choroid plexus":"5.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Excitatory neurons":"80.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"2.5"},"RNA tissue cell type enrichment":["Prostate - Fibroblasts","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014011"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014011":"AB_1856709"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"}},{"Gene":"HTR2B","Gene synonym":["5-HT(2B)","5-HT2B"],"Ensembl":"ENSG00000135914","Gene description":"5-hydroxytryptamine receptor 2B","Uniprot":["P41595"],"Chromosome":"2","Position":"231108230-231125042","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Behavior"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"17.4","cervix":"21.5","endometrium 1":"18.8","smooth muscle":"16.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"16.7","Microglial cells":"4.6","Peritubular cells":"4.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"basophil":"1.8","T-reg":"1.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"granulocytes":"1.8","T-cells":"1.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"18.0","skin cancer":"12.9"},"RNA tissue cell type enrichment":["Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012867","HPA063658"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA012867":"AB_1856710","HPA063658":"AB_2685079"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"}},{"Gene":"HTR2C","Gene synonym":["5-HT2C","5HTR2C","HTR1C"],"Ensembl":"ENSG00000147246","Gene description":"5-hydroxytryptamine receptor 2C","Uniprot":["P28335"],"Chromosome":"X","Position":"114584078-114910061","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Behavior"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"choroid plexus":"271.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"23.3","Inhibitory neurons":"53.5","Oligodendrocyte precursor cells":"9.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"3.5","Myeloma":"2.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"}},{"Gene":"HTR3A","Gene synonym":["5-HT3A","5-HT3R","HTR3"],"Ensembl":"ENSG00000166736","Gene description":"5-hydroxytryptamine receptor 3A","Uniprot":["P46098"],"Chromosome":"11","Position":"113974881-113990313","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"8.0","salivary gland":"5.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Ductal cells":"23.4","Exocrine glandular cells":"70.9","Pancreatic endocrine cells":"24.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"ovarian cancer":"15.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"memory B-cell":"3.9","naive B-cell":"13.8","plasmacytoid DC":"11.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"127","RNA blood lineage specific nTPM":{"B-cells":"13.8","dendritic cells":"11.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"lymphoma":"8.6","Neuroblastoma":"15.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"16","RNA pig brain regional specific nTPM":{"amygdala":"1.7","cerebral cortex":"2.7","hippocampal formation":"2.5"},"Antibody":["HPA069442"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069442":"AB_2732132"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.26e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.26e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"}},{"Gene":"HTR3B","Gene synonym":["5-HT3B"],"Ensembl":"ENSG00000149305","Gene description":"5-hydroxytryptamine receptor 3B","Uniprot":["O95264"],"Chromosome":"11","Position":"113904677-113949078","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"2.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"4.4","Melanocytes":"1.7","Rod photoreceptor cells":"1.6","Sertoli cells":"2.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"2.5"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Neuroblastoma":"3.7"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039559"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039559":"AB_10672779"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"HTR3C","Gene synonym":[],"Ensembl":"ENSG00000178084","Gene description":"5-hydroxytryptamine receptor 3C","Uniprot":["Q8WXA8"],"Chromosome":"3","Position":"184053047-184060673","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lung":"2.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"}},{"Gene":"HTR3D","Gene synonym":[],"Ensembl":"ENSG00000186090","Gene description":"5-hydroxytryptamine receptor 3D","Uniprot":["Q70Z44"],"Chromosome":"3","Position":"184031544-184039369","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"HTR3E","Gene synonym":[],"Ensembl":"ENSG00000186038","Gene description":"5-hydroxytryptamine receptor 3E","Uniprot":["A5X5Y0"],"Chromosome":"3","Position":"184097064-184106995","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"3.5","Inhibitory neurons":"1.1","Oligodendrocyte precursor cells":"2.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049764"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049764":"AB_2680869"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"}},{"Gene":"HTR4","Gene synonym":["5-HT4"],"Ensembl":"ENSG00000164270","Gene description":"5-hydroxytryptamine receptor 4","Uniprot":["Q13639"],"Chromosome":"5","Position":"148451032-148677235","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"12.1","heart muscle":"4.5","intestine":"9.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"41.5","Inhibitory neurons":"43.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"12.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"2.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040591"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040591":"AB_2677028"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-5"}},{"Gene":"HTR5A","Gene synonym":["5-HT5A"],"Ensembl":"ENSG00000157219","Gene description":"5-hydroxytryptamine receptor 5A","Uniprot":["P47898"],"Chromosome":"7","Position":"155070324-155087392","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"3.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"9.6","Excitatory neurons":"7.5","Inhibitory neurons":"9.8","Late spermatids":"12.4","Sertoli cells":"2.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017467"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB017467":"AB_2122566"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"HTR6","Gene synonym":["5-HT6","5-HT6R"],"Ensembl":"ENSG00000158748","Gene description":"5-hydroxytryptamine receptor 6","Uniprot":["P50406"],"Chromosome":"1","Position":"19664875-19680966","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"brain":"9.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1.6","Spermatogonia":"1.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"0.6"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"basal ganglia":"9.7","cerebral cortex":"2.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"2.2","Rhabdoid":"3.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068165"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA068165":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"}},{"Gene":"HTR7","Gene synonym":["5-HT7"],"Ensembl":"ENSG00000148680","Gene description":"5-hydroxytryptamine receptor 7","Uniprot":["P34969"],"Chromosome":"10","Position":"90740823-90858039","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"7.6","parathyroid gland":"13.1","testis":"8.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"8.8","Excitatory neurons":"5.8","Inhibitory neurons":"23.8","Spermatocytes":"11.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"cervical cancer":"0.9","head and neck cancer":"3.3","lung cancer":"0.9","urothelial cancer":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"myeloid DC":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"1.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"8.2"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022708","HPA073617"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles","Cytosol"],"Antibody RRID":{"CAB022708":null,"HPA073617":"AB_2732228"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"}},{"Gene":"HTRA2","Gene synonym":["OMI","PARK13","PRSS25"],"Ensembl":"ENSG00000115317","Gene description":"HtrA serine peptidase 2","Uniprot":["O43464"],"Chromosome":"2","Position":"74529725-74533332","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004004","HPA006602","HPA027366"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB004004":"AB_326421","HPA006602":"AB_2667622","HPA027366":"AB_1851301"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.77e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"}},{"Gene":"HTT","Gene synonym":["HD","IT15"],"Ensembl":"ENSG00000197386","Gene description":"Huntingtin","Uniprot":["P42858"],"Chromosome":"4","Position":"3041363-3243960","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002756","HPA026114","HPA051524"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"36000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB002756":null,"HPA026114":"AB_1851330","HPA051524":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.41e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"}},{"Gene":"HUNK","Gene synonym":[],"Ensembl":"ENSG00000142149","Gene description":"Hormonally up-regulated Neu-associated kinase","Uniprot":["P57058"],"Chromosome":"21","Position":"31873020-32044633","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"9.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"18.7","Horizontal cells":"26.9","Inhibitory neurons":"107.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"9.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027295","HPA027372"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA027295":"AB_2672203","HPA027372":"AB_2672239"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.48e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"}},{"Gene":"HUWE1","Gene synonym":["Ib772","KIAA0312","UREB1"],"Ensembl":"ENSG00000086758","Gene description":"HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1","Uniprot":["Q7Z6Z7"],"Chromosome":"X","Position":"53532096-53686728","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms","Differentiation","DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"500.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002548","CAB022718"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"73000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB022718":null,"HPA002548":"AB_1080489"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"}},{"Gene":"HVCN1","Gene synonym":["Hv1","MGC15619","VSOP"],"Ensembl":"ENSG00000122986","Gene description":"Hydrogen voltage gated channel 1","Uniprot":["Q96D96"],"Chromosome":"12","Position":"110627841-110704950","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"162.1","lymphoid tissue":"72.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"182.2","dendritic cells":"70.3","Early spermatids":"85.7","Hofbauer cells":"63.7","Late spermatids":"72.5","Spermatocytes":"97.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Leukemia":"31.5","lymphoma":"38.8","Myeloma":"32.1"},"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Prostate - Fibroblasts","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039329"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039329":"AB_10674284"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"}},{"Gene":"HYAL2","Gene synonym":["LuCa-2","LUCA2"],"Ensembl":"ENSG00000068001","Gene description":"Hyaluronidase 2","Uniprot":["Q12891"],"Chromosome":"3","Position":"50317790-50322782","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"282.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Adipocytes":"490.3","Endothelial cells":"276.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036436"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036436":"AB_10670104"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"}},{"Gene":"HYAL4","Gene synonym":[],"Ensembl":"ENSG00000106302","Gene description":"Hyaluronidase 4","Uniprot":["Q2M3T9"],"Chromosome":"7","Position":"123828983-123877481","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"4.0","skeletal muscle":"3.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"2.3","Cytotrophoblasts":"4.1","Extravillous trophoblasts":"8.5","Ionocytes":"1.5","Spermatocytes":"1.4","Spermatogonia":"3.8","Syncytiotrophoblasts":"2.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"48","RNA cancer specific FPKM":{"testis cancer":"8.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029453"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029453":"AB_10601432"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-3"}},{"Gene":"HYI","Gene synonym":["HT036"],"Ensembl":"ENSG00000178922","Gene description":"Hydroxypyruvate isomerase (putative)","Uniprot":["Q5T013"],"Chromosome":"1","Position":"43450989-43453989","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"187.2","Pancreatic endocrine cells":"187.2","Proximal enterocytes":"207.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"29.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040092"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA040092":"AB_10795374"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.18e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.96e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.55e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.72e-5"}},{"Gene":"ICA1","Gene synonym":["ICA69","ICAp69"],"Ensembl":"ENSG00000003147","Gene description":"Islet cell autoantigen 1","Uniprot":["Q05084"],"Chromosome":"7","Position":"8113184-8262687","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"453.9","Late spermatids":"956.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"T-reg":"29.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"29.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"83.7"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skeletal muscle - Endothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017646","HPA061452"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017646":"AB_1851382","HPA061452":"AB_2684525"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.23e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"}},{"Gene":"ICAM1","Gene synonym":["BB2","CD54"],"Ensembl":"ENSG00000090339","Gene description":"Intercellular adhesion molecule 1","Uniprot":["P05362"],"Chromosome":"19","Position":"10271093-10286615","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"219.3","urinary bladder":"215.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"523.4","Alveolar cells type 2":"268.2","Endothelial cells":"270.5","Exocrine glandular cells":"317.2","Langerhans cells":"219.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002126","CAB002142","HPA004877"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":87900000,"Blood concentration - Conc. blood MS [pg\/L]":"2200000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"CAB002142":"AB_563596","HPA002126":"AB_1078470","HPA004877":"AB_1846317"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.09e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"}},{"Gene":"ICAM2","Gene synonym":["CD102"],"Ensembl":"ENSG00000108622","Gene description":"Intercellular adhesion molecule 2","Uniprot":["P13598"],"Chromosome":"17","Position":"64002594-64020634","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"168.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"351.0","Endothelial cells":"214.4","monocytes":"114.0","NK-cells":"87.6","Plasma cells":"123.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bile duct cancer":"27.7","Leukemia":"72.6","lymphoma":"49.9","Myeloma":"72.4","ovarian cancer":"30.4","pancreatic cancer":"44.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Lung - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071155"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"730000000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA071155":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"}},{"Gene":"ICAM3","Gene synonym":["CD50","CDW50","ICAM-R"],"Ensembl":"ENSG00000076662","Gene description":"Intercellular adhesion molecule 3","Uniprot":["P32942"],"Chromosome":"19","Position":"10333776-10339661","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Phagocytosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"206.5","liver":"73.2","lymphoid tissue":"85.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"146.4","Hepatocytes":"177.1","monocytes":"254.2","NK-cells":"246.5","Plasma cells":"138.3","T-cells":"179.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1948.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1948.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"98.4","lymphoma":"73.3","Myeloma":"127.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Kidney - T-cells","Lung - Neutrophil_2","Prostate - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002498","HPA049820"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"390000000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Nuclear membrane"],"Antibody RRID":{"CAB002498":"AB_563593","HPA049820":"AB_2680897"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"}},{"Gene":"ICAM4","Gene synonym":["CD242","LW"],"Ensembl":"ENSG00000105371","Gene description":"Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)","Uniprot":["Q14773"],"Chromosome":"19","Position":"10286955-10288522","Protein class":["Blood group antigen proteins","CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Blood group antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"13.4","lung":"9.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"25.5","Alveolar cells type 1":"20.1","Alveolar cells type 2":"80.3","Endothelial cells":"21.7","Erythroid cells":"33.6","monocytes":"28.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"non-classical monocyte":"215.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"monocytes":"215.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"37.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ICAM5","Gene synonym":["TLCN","TLN"],"Ensembl":"ENSG00000105376","Gene description":"Intercellular adhesion molecule 5","Uniprot":["Q9UMF0"],"Chromosome":"19","Position":"10289952-10296778","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"40.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"14.3","Alveolar cells type 2":"14.1","Breast myoepithelial cells":"5.8","Excitatory neurons":"17.4","Thymic epithelial cells":"8.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"4.8"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"239","RNA brain regional specific nTPM":{"amygdala":"13.6","basal ganglia":"15.4","cerebral cortex":"26.2","hippocampal formation":"40.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"19.3"},"RNA tissue cell type enrichment":["Colon - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"14","RNA pig brain regional specific nTPM":{"amygdala":"40.8","basal ganglia":"45.1","cerebral cortex":"50.7","hippocampal formation":"76.2","olfactory bulb":"27.4"},"Antibody":["HPA008943","HPA009083","CAB025178"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025178":null,"HPA008943":"AB_1079095","HPA009083":"AB_1079094"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"}},{"Gene":"ICMT","Gene synonym":["HSTE14","PCCMT","PPMT"],"Ensembl":"ENSG00000116237","Gene description":"Isoprenylcysteine carboxyl methyltransferase","Uniprot":["O60725"],"Chromosome":"1","Position":"6221193-6235972","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"90.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebellum":"112.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032024","HPA032025"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA032024":"AB_2674115","HPA032025":"AB_10601819"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.79e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"}},{"Gene":"ICOS","Gene synonym":["AILIM","CD278"],"Ensembl":"ENSG00000163600","Gene description":"Inducible T cell costimulator","Uniprot":["Q9Y6W8"],"Chromosome":"2","Position":"203936763-203961577","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"bone marrow":"16.5","lymphoid tissue":"20.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"T-cells":"89.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"29.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"54","RNA blood lineage specific nTPM":{"T-cells":"29.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"2.4","lymphoma":"3.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Kidney - T-cells","Liver - T-cells","Prostate - T-cells","Skin - T-cells","Testis - Spermatogonia","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032575","HPA034865"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB032575":"AB_2122593","HPA034865":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.80e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-3"}},{"Gene":"ICOSLG","Gene synonym":["B7-H2","B7h","B7H2","B7RP-1","B7RP1","CD275","GL50","ICOS-L","ICOSL","KIAA0653"],"Ensembl":"ENSG00000160223","Gene description":"Inducible T cell costimulator ligand","Uniprot":["O75144"],"Chromosome":"21","Position":"44217014-44240966","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","B-cell activation","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"18.2","brain":"33.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"22.0","dendritic cells":"70.4","Langerhans cells":"34.7","Schwann cells":"49.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"2.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026037","HPA029179","CAB079997"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Plasma membrane","Cytoplasmic bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB026037":null,"CAB079997":null,"HPA029179":"AB_2732445"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"}},{"Gene":"IDE","Gene synonym":[],"Ensembl":"ENSG00000119912","Gene description":"Insulin degrading enzyme","Uniprot":["P14735"],"Chromosome":"10","Position":"92451684-92574096","Protein class":["Enzymes","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Allosteric enzyme","Host cell receptor for virus entry","Hydrolase","Metalloprotease","Protease","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063478"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"310000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063478":"AB_2685020"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.69e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.53e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"}},{"Gene":"IDH3G","Gene synonym":[],"Ensembl":"ENSG00000067829","Gene description":"Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma","Uniprot":["P51553"],"Chromosome":"X","Position":"153785766-153794523","Protein class":["Citric acid cycle related proteins","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Tricarboxylic acid cycle"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"289.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000425","HPA002017"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoli","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA000425":"AB_1079097","HPA002017":"AB_1079096"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.73e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"}},{"Gene":"IER3","Gene synonym":["DIF-2","IEX-1","IEX-1L","PRG1"],"Ensembl":"ENSG00000137331","Gene description":"Immediate early response 3","Uniprot":["P46695"],"Chromosome":"6","Position":"30743199-30744548","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"2987.9","Suprabasal keratinocytes":"2132.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"30.2","skin cancer":"37.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043847"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043847":"AB_2678699"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.57e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.36e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.10e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"}},{"Gene":"IER3IP1","Gene synonym":[],"Ensembl":"ENSG00000134049","Gene description":"Immediate early response 3 interacting protein 1","Uniprot":["Q9Y5U9"],"Chromosome":"18","Position":"47152834-47176364","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Diabetes mellitus","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"319.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010027"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA010027":"AB_1079098"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.47e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.59e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"}},{"Gene":"IFFO1","Gene synonym":["HOM-TES-103","IFFO"],"Ensembl":"ENSG00000010295","Gene description":"Intermediate filament family orphan 1","Uniprot":["Q0D2I5"],"Chromosome":"12","Position":"6538961-6556073","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Breast - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069344"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069344":"AB_2686126"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.53e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.47e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"}},{"Gene":"IFI27","Gene synonym":["FAM14D","ISG12","P27"],"Ensembl":"ENSG00000165949","Gene description":"Interferon alpha inducible protein 27","Uniprot":["P40305"],"Chromosome":"14","Position":"94104836-94116698","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Antiviral defense","Apoptosis","Host-virus interaction","Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"3562.2","Distal enterocytes":"3300.8","Endothelial cells":"1616.6","Intestinal goblet cells":"2142.6","Paneth cells":"1898.0","Proximal enterocytes":"3146.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"7.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"monocytes":"7.0","T-cells":"2.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"997.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells","Kidney - Endothelial cells","Prostate - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028875"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA028875":"AB_10601434"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.80e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"}},{"Gene":"IFI27L1","Gene synonym":["FAM14B"],"Ensembl":"ENSG00000165948","Gene description":"Interferon alpha inducible protein 27 like 1","Uniprot":["Q96BM0"],"Chromosome":"14","Position":"94081301-94103846","Protein class":["Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"97.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"347.0","Late spermatids":"177.0","Sertoli cells":"221.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"16.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"}},{"Gene":"IFI6","Gene synonym":["6-16","FAM14C","G1P3","IFI-6-16","IFI616"],"Ensembl":"ENSG00000126709","Gene description":"Interferon alpha inducible protein 6","Uniprot":["P09912"],"Chromosome":"1","Position":"27666064-27672212","Protein class":["Predicted membrane proteins"],"Biological process":["Antiviral defense","Apoptosis","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cytotrophoblasts":"2241.3","Extravillous trophoblasts":"639.2","Syncytiotrophoblasts":"2261.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005543"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA005543":"AB_1849342"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"}},{"Gene":"IFITM1","Gene synonym":["9-27","CD225","DSPA2a","IFI17"],"Ensembl":"ENSG00000185885","Gene description":"Interferon induced transmembrane protein 1","Uniprot":["P13164"],"Chromosome":"11","Position":"310041-315272","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiviral defense","Immunity","Innate immunity","Osteogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"351.2","Endothelial cells":"308.4","Leydig cells":"227.4","NK-cells":"258.0","T-cells":"493.0","Thymic epithelial cells":"302.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"eosinophil":"1494.7","gdT-cell":"2906.3","MAIT T-cell":"2003.4","memory CD4 T-cell":"3120.6","memory CD8 T-cell":"3000.3","naive CD4 T-cell":"2939.3","naive CD8 T-cell":"2996.4","neutrophil":"2741.6","NK-cell":"4679.9","T-reg":"1944.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"2741.6","NK-cells":"4679.9","T-cells":"3120.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Heart muscle - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004810","CAB017615"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"CAB017615":"AB_2264496","HPA004810":"AB_1851419"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.77e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"}},{"Gene":"IFITM10","Gene synonym":["DSPA3"],"Ensembl":"ENSG00000244242","Gene description":"Interferon induced transmembrane protein 10","Uniprot":["A6NMD0"],"Chromosome":"11","Position":"1732406-1750595","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adrenal gland":"2.6","bone marrow":"1.5","brain":"3.2","choroid plexus":"1.8","retina":"1.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"10.3","Inhibitory neurons":"11.1","Oligodendrocyte precursor cells":"38.0","Respiratory ciliated cells":"15.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"4.7"},"RNA tissue cell type enrichment":["Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"}},{"Gene":"IFITM2","Gene synonym":["1-8D","DSPA2c"],"Ensembl":"ENSG00000185201","Gene description":"Interferon induced transmembrane protein 2","Uniprot":["Q01629"],"Chromosome":"11","Position":"303655-309397","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Antiviral defense","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"943.1","monocytes":"1676.7","NK-cells":"1445.3","Thymic epithelial cells":"998.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"23410.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"23410.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004337","HPA044731"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA004337":"AB_1851427","HPA044731":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.37e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"}},{"Gene":"IFITM3","Gene synonym":["1-8U","DSPA2b"],"Ensembl":"ENSG00000142089","Gene description":"Interferon induced transmembrane protein 3","Uniprot":["Q01628"],"Chromosome":"11","Position":"319676-329475","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiviral defense","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"2371.6","Thymic epithelial cells":"3637.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2907.6","non-classical monocyte":"3344.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2907.6","monocytes":"3344.3","NK-cells":"926.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004337"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004337":"AB_1851427"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.78e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"}},{"Gene":"IFITM5","Gene synonym":["BRIL","DSPA1","fragilis4","Hrmp1"],"Ensembl":"ENSG00000206013","Gene description":"Interferon induced transmembrane protein 5","Uniprot":["A6NNB3"],"Chromosome":"11","Position":"298200-299526","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Mineral balance"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"4.9","pancreas":"7.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"cerebral cortex":"4.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039258"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA039258":"AB_10673608"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"}},{"Gene":"IFNAR1","Gene synonym":["IFNAR","IFRC"],"Ensembl":"ENSG00000142166","Gene description":"Interferon alpha and beta receptor subunit 1","Uniprot":["P17181"],"Chromosome":"21","Position":"33324429-33359864","Protein class":["Cancer-related genes","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029226"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029226":"AB_2672954"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"}},{"Gene":"IFNAR2","Gene synonym":["IFNABR"],"Ensembl":"ENSG00000159110","Gene description":"Interferon alpha and beta receptor subunit 2","Uniprot":["P48551"],"Chromosome":"21","Position":"33229901-33265675","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"87.4","Plasma cells":"84.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"117.8"},"RNA tissue cell type enrichment":["Colon - Endothelial cells","Heart muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.54e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"}},{"Gene":"IFNGR1","Gene synonym":["CD119","IFNGR"],"Ensembl":"ENSG00000027697","Gene description":"Interferon gamma receptor 1","Uniprot":["P15260"],"Chromosome":"6","Position":"137197485-137219449","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"852.6","Ionocytes":"638.7","monocytes":"412.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025889","HPA029213","HPA063871"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB025889":null,"HPA029213":"AB_10601023","HPA063871":"AB_2685138"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.48e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-3"}},{"Gene":"IFNGR2","Gene synonym":["AF-1","IFNGT1"],"Ensembl":"ENSG00000159128","Gene description":"Interferon gamma receptor 2","Uniprot":["P38484"],"Chromosome":"21","Position":"33403413-33479348","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"218.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"661.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001535"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA001535":"AB_1078432"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"}},{"Gene":"IFNK","Gene synonym":[],"Ensembl":"ENSG00000147896","Gene description":"Interferon kappa","Uniprot":["Q9P0W0"],"Chromosome":"9","Position":"27524290-27526498","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Antiviral defense"],"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"brain":"4.1","choroid plexus":"2.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"cervical cancer":"0.5","head and neck cancer":"0.6","urothelial cancer":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"35","RNA cell line specific nTPM":{"Bladder cancer":"3.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"IFNLR1","Gene synonym":["CRF2\/12","IFNLR","IL-28R1","IL28RA"],"Ensembl":"ENSG00000185436","Gene description":"Interferon lambda receptor 1","Uniprot":["Q8IU57"],"Chromosome":"1","Position":"24154168-24187959","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Antiviral defense"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"13.4","dendritic cells":"14.9","Proximal enterocytes":"16.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"4.9","naive B-cell":"5.9","plasmacytoid DC":"11.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"5.9","dendritic cells":"11.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"23.1"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 2","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017319"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017319":"AB_1851708"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.12e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"}},{"Gene":"IFRD1","Gene synonym":["PC4","TIS7"],"Ensembl":"ENSG00000006652","Gene description":"Interferon related developmental regulator 1","Uniprot":["O00458"],"Chromosome":"7","Position":"112422887-112481017","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"64.2","neutrophil":"112.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"112.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024122","HPA072413"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA024122":"AB_1851452","HPA072413":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.45e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"}},{"Gene":"IFRD2","Gene synonym":["IFNRP","SKMc15","SM15"],"Ensembl":"ENSG00000214706","Gene description":"Interferon related developmental regulator 2","Uniprot":["Q12894"],"Chromosome":"3","Position":"50287732-50292918","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"155.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068560"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA068560":"AB_2686005"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.22e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"}},{"Gene":"IFT140","Gene synonym":["gs114","KIAA0590","WDTC2"],"Ensembl":"ENSG00000187535","Gene description":"Intraflagellar transport 140","Uniprot":["Q96RY7"],"Chromosome":"16","Position":"1510427-1612072","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"28.8","Late spermatids":"26.4","Respiratory ciliated cells":"37.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"3.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042197"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042197":"AB_2677895"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-3"}},{"Gene":"IFT57","Gene synonym":["ESRRBL1","FLJ10147","HIPPI","MHS4R2"],"Ensembl":"ENSG00000114446","Gene description":"Intraflagellar transport 57","Uniprot":["Q9NWB7"],"Chromosome":"3","Position":"108160812-108222435","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Ciliopathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"1483.4","Late spermatids":"2942.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"41.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035514","HPA035515"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA035514":"AB_10601757","HPA035515":"AB_10696505"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.96e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.63e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"}},{"Gene":"IGDCC3","Gene synonym":["HsT18880","PUNC"],"Ensembl":"ENSG00000174498","Gene description":"Immunoglobulin superfamily DCC subclass member 3","Uniprot":["Q8IVU1"],"Chromosome":"15","Position":"65327127-65378002","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.3","parathyroid gland":"5.1","placenta":"6.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"103.5","Early spermatids":"21.5","Late spermatids":"101.0","Syncytiotrophoblasts":"35.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"2.2","testis cancer":"5.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"testis cancer":"41.9"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015713"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA015713":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"}},{"Gene":"IGDCC4","Gene synonym":["LOC57722","NOPE"],"Ensembl":"ENSG00000103742","Gene description":"Immunoglobulin superfamily DCC subclass member 4","Uniprot":["Q8TDY8"],"Chromosome":"15","Position":"65381484-65422947","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.3","skeletal muscle":"10.6","tongue":"14.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"18.0","Cone photoreceptor cells":"12.1","Leydig cells":"34.1","Melanocytes":"17.4","Microglial cells":"13.7","Oligodendrocyte precursor cells":"16.8","Rod photoreceptor cells":"13.4","Skeletal myocytes":"21.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"6.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"5.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Lung - Fibroblast_2","Prostate - Fibroblasts","Skin - Fibroblast_1","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008510","HPA008576"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"64000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008510":null,"HPA008576":"AB_1079496"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-3"}},{"Gene":"IGF1R","Gene synonym":["CD221","IGFIR","IGFR","JTK13","MGC18216"],"Ensembl":"ENSG00000140443","Gene description":"Insulin like growth factor 1 receptor","Uniprot":["P08069"],"Chromosome":"15","Position":"98648539-98964530","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"236.0","Inhibitory neurons":"190.3","Microglial cells":"239.0","Oligodendrocyte precursor cells":"227.7","Oligodendrocytes":"246.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"4.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"4.3","T-cells":"1.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010268","HPA045563"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"46000","Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010268":"AB_671792","HPA045563":"AB_2679368"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.75e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"IGF2","Gene synonym":["C11orf43","FLJ44734","IGF-II"],"Ensembl":"ENSG00000167244","Gene description":"Insulin like growth factor 2","Uniprot":["P01344"],"Chromosome":"11","Position":"2129112-2141238","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism","Osteogenesis"],"Molecular function":["Growth factor","Hormone","Mitogen"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"placenta":"2749.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"76.8","Cytotrophoblasts":"118.5","Extravillous trophoblasts":"253.1","Leydig cells":"165.1","Syncytiotrophoblasts":"177.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"86.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"577.1","Sarcoma":"553.6"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Fibroblast_2","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007556"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":609000000,"Blood concentration - Conc. blood MS [pg\/L]":"1200000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA007556":"AB_2667860"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.12e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"}},{"Gene":"IGF2R","Gene synonym":["CD222","CI-M6PR","CI-MPR","CIMPR","M6P-R","MPR1","MPR300","MPRI"],"Ensembl":"ENSG00000197081","Gene description":"Insulin like growth factor 2 receptor","Uniprot":["P11717"],"Chromosome":"6","Position":"159969082-160113507","Protein class":["Cancer-related genes","CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"69.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"203.2","NK-cells":"205.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"4.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Macrophages","Lung - Neutrophil_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009661","HPA011332"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB009661":"AB_2122795","HPA011332":"AB_1846276"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.01e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.92e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.08e-4"}},{"Gene":"IGFALS","Gene synonym":["ALS"],"Ensembl":"ENSG00000099769","Gene description":"Insulin like growth factor binding protein acid labile subunit","Uniprot":["P35858"],"Chromosome":"16","Position":"1790413-1794971","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"liver":"116.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hepatocytes":"66.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"11.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040692","HPA040948"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":14700000000,"Blood concentration - Conc. blood MS [pg\/L]":"26000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040692":"AB_10794067","HPA040948":"AB_10794999"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.06e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.97e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"}},{"Gene":"IGFBP2","Gene synonym":["IBP2"],"Ensembl":"ENSG00000115457","Gene description":"Insulin like growth factor binding protein 2","Uniprot":["P18065"],"Chromosome":"2","Position":"216632828-216664436","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Growth regulation"],"Molecular function":["Growth factor binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"956.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"664.3","Endometrial stromal cells":"1471.5","Granulosa cells":"1524.4","Theca cells":"1709.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Exocrine glandular cells","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077723"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":303000000,"Blood concentration - Conc. blood MS [pg\/L]":"810000000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA077723":"AB_2686853"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.43e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.22e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"}},{"Gene":"IGFLR1","Gene synonym":["FLJ22573","TMEM149","U2AF1L4"],"Ensembl":"ENSG00000126246","Gene description":"IGF like family receptor 1","Uniprot":["Q9H665"],"Chromosome":"19","Position":"35738801-35742453","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"49.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"20.6","dendritic cells":"43.2","Hepatocytes":"21.3","Langerhans cells":"45.0","Macrophages":"20.8","Plasma cells":"31.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"899.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"899.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"18.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012369","HPA070778"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA012369":"AB_1858095","HPA070778":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.55e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.59e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-3"}},{"Gene":"IGHA1","Gene synonym":[],"Ensembl":"ENSG00000211895","Gene description":"Immunoglobulin heavy constant alpha 1","Uniprot":["P01876"],"Chromosome":"14","Position":"105703995-105708665","Protein class":["Disease related genes","Immunoglobulin genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"7411.2","lymphoid tissue":"6397.6","salivary gland":"8904.9","stomach 1":"6664.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Plasma cells":"70370.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"203","RNA blood cell specific nTPM":{"memory B-cell":"2571.8","naive B-cell":"1114.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"284","RNA blood lineage specific nTPM":{"B-cells":"2571.8"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"26","RNA cell line specific nTPM":{"Myeloma":"2211.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Plasma cells","Adipose visceral - Plasma cells","Breast - Plasma cells","Colon - Plasma cells","Heart muscle - Plasma cells","Kidney - Plasma cells","Liver - Plasma cells","Lung - Plasma cells","Pancreas - Plasma cells","Prostate - Plasma cells","Skeletal muscle - Plasma cells","Skin - Plasma cells","Stomach - Plasma cells","Thyroid - Plasma cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001217","HPA006013"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Immunoglobulin genes","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000000000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001217":"AB_1079120","HPA006013":"AB_1079119"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.87e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.81e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"}},{"Gene":"IGHA2","Gene synonym":[],"Ensembl":"ENSG00000211890","Gene description":"Immunoglobulin heavy constant alpha 2 (A2m marker)","Uniprot":["P01877"],"Chromosome":"14","Position":"105583731-105588395","Protein class":["Immunoglobulin genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"5017.7","salivary gland":"3728.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"32","RNA single cell type specific nTPM":{"Plasma cells":"10082.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"876","RNA blood cell specific nTPM":{"memory B-cell":"279.6","naive B-cell":"123.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"1214","RNA blood lineage specific nTPM":{"B-cells":"279.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"164","RNA cell line specific nTPM":{"lymphoma":"13.2","Myeloma":"46.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Plasma cells","Adipose visceral - Plasma cells","Breast - Plasma cells","Colon - Plasma cells","Heart muscle - Plasma cells","Liver - Plasma cells","Lung - Plasma cells","Pancreas - Plasma cells","Prostate - Plasma cells","Skeletal muscle - Plasma cells","Skin - Plasma cells","Stomach - Plasma cells","Thyroid - Plasma cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001217","HPA006013"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Immunoglobulin genes","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"67000000000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001217":"AB_1079120","HPA006013":"AB_1079119"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.98e-9"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.40e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.50e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-1"}},{"Gene":"IGHD","Gene synonym":["FLJ00382","FLJ46727","MGC29633"],"Ensembl":"ENSG00000211898","Gene description":"Immunoglobulin heavy constant delta","Uniprot":["P01880"],"Chromosome":"14","Position":"105836765-105845678","Protein class":["Immunoglobulin genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"330.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"B-cells":"454.5","Plasma cells":"700.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"58.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"63","RNA blood cell specific nTPM":{"memory B-cell":"279.1","naive B-cell":"815.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"93","RNA blood lineage specific nTPM":{"B-cells":"815.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"66","RNA cell line specific nTPM":{"Myeloma":"4050.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Plasma cells","Adipose visceral - Plasma cells","Breast - Plasma cells","Colon - Plasma cells","Heart muscle - Plasma cells","Liver - Plasma cells","Lung - Plasma cells","Pancreas - Plasma cells","Thyroid - Plasma cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012703"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Immunoglobulin genes","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB012703":"AB_10554307"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.49e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"}},{"Gene":"IGHE","Gene synonym":[],"Ensembl":"ENSG00000211891","Gene description":"Immunoglobulin heavy constant epsilon","Uniprot":["P01854"],"Chromosome":"14","Position":"105597691-105601728","Protein class":["Immunoglobulin genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"1.9","lymphoid tissue":"4.6","thyroid gland":"2.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"38","RNA single cell type specific nTPM":{"B-cells":"98.0","Plasma cells":"48.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"60","RNA cell line specific nTPM":{"Myeloma":"140.0"},"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Immunoglobulin genes","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"77000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"}},{"Gene":"IGHG1","Gene synonym":[],"Ensembl":"ENSG00000211896","Gene description":"Immunoglobulin heavy constant gamma 1 (G1m marker)","Uniprot":["P01857"],"Chromosome":"14","Position":"105736343-105743071","Protein class":["Disease related genes","FDA approved drug targets","Immunoglobulin genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"11451.9","urinary bladder":"3998.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"31","RNA single cell type specific nTPM":{"B-cells":"2040.6","Plasma cells":"6710.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"spinal cord":"12.7"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"memory B-cell":"766.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"123","RNA blood lineage specific nTPM":{"B-cells":"766.8"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Myeloma":"1216.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Plasma cells","Adipose visceral - Plasma cells","Breast - Plasma cells","Colon - Plasma cells","Heart muscle - Plasma cells","Kidney - Plasma cells","Liver - Plasma cells","Lung - Plasma cells","Pancreas - Plasma cells","Prostate - Plasma cells","Skeletal muscle - Plasma cells","Skin - Plasma cells","Stomach - Plasma cells","Thyroid - Plasma cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001245","CAB008642"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Immunoglobulin genes","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"230000000000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB008642":"AB_1617595","HPA001245":"AB_1079121"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.67e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"}},{"Gene":"IGHG2","Gene synonym":[],"Ensembl":"ENSG00000211893","Gene description":"Immunoglobulin heavy constant gamma 2 (G2m marker)","Uniprot":["P01859"],"Chromosome":"14","Position":"105639559-105644790","Protein class":["FDA approved drug targets","Immunoglobulin genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"lymphoid tissue":"4319.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Plasma cells":"4718.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"447","RNA blood cell specific nTPM":{"memory B-cell":"339.0","naive B-cell":"119.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"661","RNA blood lineage specific nTPM":{"B-cells":"339.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Myeloma":"53.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Plasma cells","Adipose visceral - Plasma cells","Breast - Plasma cells","Colon - Plasma cells","Heart muscle - Plasma cells","Kidney - Plasma cells","Liver - Plasma cells","Lung - Plasma cells","Pancreas - Plasma cells","Prostate - Plasma cells","Skeletal muscle - Plasma cells","Skin - Plasma cells","Stomach - Plasma cells","Thyroid - Plasma cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001245"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Immunoglobulin genes","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"250000000000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001245":"AB_1079121"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.53e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.30e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.30e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"}},{"Gene":"IGHG3","Gene synonym":[],"Ensembl":"ENSG00000211897","Gene description":"Immunoglobulin heavy constant gamma 3 (G3m marker)","Uniprot":[],"Chromosome":"14","Position":"105764503-105771405","Protein class":["Immunoglobulin genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lymphoid tissue":"1289.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"25","RNA single cell type specific nTPM":{"B-cells":"1189.2","Plasma cells":"2469.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"415","RNA blood cell specific nTPM":{"memory B-cell":"211.0","naive B-cell":"64.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"636","RNA blood lineage specific nTPM":{"B-cells":"211.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"29","RNA cell line specific nTPM":{"lymphoma":"76.6","Myeloma":"22.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Plasma cells","Adipose visceral - Plasma cells","Breast - Plasma cells","Colon - Plasma cells","Heart muscle - Plasma cells","Kidney - Plasma cells","Liver - Plasma cells","Lung - Plasma cells","Pancreas - Plasma cells","Prostate - Plasma cells","Skeletal muscle - Plasma cells","Skin - Plasma cells","Stomach - Plasma cells","Thyroid - Plasma cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Immunoglobulin genes","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.00e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.46e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"}},{"Gene":"IGHG4","Gene synonym":[],"Ensembl":"ENSG00000211892","Gene description":"Immunoglobulin heavy constant gamma 4 (G4m marker)","Uniprot":["P01861"],"Chromosome":"14","Position":"105620506-105626066","Protein class":["FDA approved drug targets","Immunoglobulin genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"2478.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"429.3","Basal keratinocytes":"123.6","Plasma cells":"568.0","T-cells":"129.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"457","RNA blood cell specific nTPM":{"memory B-cell":"122.7","naive B-cell":"73.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"571","RNA blood lineage specific nTPM":{"B-cells":"122.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"38","RNA cell line specific nTPM":{"lymphoma":"133.9","Myeloma":"34.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Plasma cells","Adipose visceral - Mesothelial cells","Breast - Plasma cells","Colon - Plasma cells","Heart muscle - Plasma cells","Kidney - Plasma cells","Lung - Plasma cells","Prostate - Plasma cells","Skeletal muscle - Plasma cells","Skin - Plasma cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001245"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Immunoglobulin genes","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001245":"AB_1079121"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.16e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.09e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"}},{"Gene":"IGHM","Gene synonym":[],"Ensembl":"ENSG00000211899","Gene description":"Immunoglobulin heavy constant mu","Uniprot":["P01871"],"Chromosome":"14","Position":"105851705-105856218","Protein class":["Disease related genes","Immunoglobulin genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"1315.0","lymphoid tissue":"4112.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"2770.0","Plasma cells":"8854.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"memory B-cell":"4278.4","naive B-cell":"6731.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"B-cells":"6731.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"17","RNA cell line specific nTPM":{"Leukemia":"375.1","lymphoma":"1452.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Plasma cells","Adipose visceral - Plasma cells","Breast - Plasma cells","Colon - Plasma cells","Heart muscle - Plasma cells","Liver - Plasma cells","Lung - Plasma cells","Pancreas - Plasma cells","Prostate - Plasma cells","Skeletal muscle - Plasma cells","Skin - Plasma cells","Stomach - Plasma cells","Thyroid - Plasma cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008643"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Immunoglobulin genes","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000000000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB008643":"AB_1617732"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.49e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.70e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.20e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"}},{"Gene":"IGLL1","Gene synonym":["14.1","CD179B","IGL5","IGLL","IGVPB"],"Ensembl":"ENSG00000128322","Gene description":"Immunoglobulin lambda like polypeptide 1","Uniprot":["P15814"],"Chromosome":"22","Position":"23573125-23580302","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"70.0","testis":"25.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"44.1","Late spermatids":"165.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"endometrial cancer":"0.5","lung cancer":"0.5","stomach cancer":"2.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"memory B-cell":"12.0","naive B-cell":"14.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"B-cells":"14.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Leukemia":"389.5","lymphoma":"133.7"},"RNA tissue cell type enrichment":["Breast - Plasma cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051134","HPA071406"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"48000000000","Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA051134":"AB_2681356","HPA071406":"AB_2686393"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-6"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"}},{"Gene":"IGLL5","Gene synonym":[],"Ensembl":"ENSG00000254709","Gene description":"Immunoglobulin lambda like polypeptide 5","Uniprot":["B9A064"],"Chromosome":"22","Position":"22887780-22896111","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"408.3","lymphoid tissue":"674.1","stomach 1":"308.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Plasma cells":"1468.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"226","RNA blood cell specific nTPM":{"memory B-cell":"515.9","naive B-cell":"615.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"246","RNA blood lineage specific nTPM":{"B-cells":"615.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Myeloma":"1376.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"53000000000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.10e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.41e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.94e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"}},{"Gene":"IGSF1","Gene synonym":["IGCD1","IGDC1","INHBP","KIAA0364","MGC75490","PGSF2"],"Ensembl":"ENSG00000147255","Gene description":"Immunoglobulin superfamily member 1","Uniprot":["Q8N6C5"],"Chromosome":"X","Position":"131273506-131578899","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Congenital hypothyroidism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"73.4","pituitary gland":"167.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"3.8","Bipolar cells":"10.9","Breast glandular cells":"3.8","Pancreatic endocrine cells":"5.2","Schwann cells":"9.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"thyroid cancer":"65.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"10.9"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"144.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012732","HPA035582"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA012732":"AB_2732404","HPA035582":"AB_2674687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.25e-8"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"}},{"Gene":"IGSF11","Gene synonym":["BT-IgSF","CT119","Igsf13","MGC35227","VSIG3"],"Ensembl":"ENSG00000144847","Gene description":"Immunoglobulin superfamily member 11","Uniprot":["Q5DX21"],"Chromosome":"3","Position":"118900557-119146068","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Growth regulation"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"46.3","ovary":"16.2","retina":"50.6","testis":"35.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"129.7","Early spermatids":"219.2","Excitatory neurons":"76.7","Inhibitory neurons":"135.9","Late spermatids":"350.8","Oligodendrocytes":"267.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"9.2","melanoma":"10.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"skin cancer":"18.0"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Kidney - Proximal tubular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046377"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA046377":"AB_10966195"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"}},{"Gene":"IGSF21","Gene synonym":["MGC15730","RP11-121A23.1"],"Ensembl":"ENSG00000117154","Gene description":"Immunoglobin superfamily member 21","Uniprot":["Q96ID5"],"Chromosome":"1","Position":"18107798-18378483","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"51.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"167.2","Excitatory neurons":"81.0","Microglial cells":"73.0","Oligodendrocyte precursor cells":"135.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"breast cancer":"4.1","glioma":"8.6","prostate cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"4.1","thyroid cancer":"7.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Kidney - Macrophages","Pancreas - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"}},{"Gene":"IGSF23","Gene synonym":[],"Ensembl":"ENSG00000216588","Gene description":"Immunoglobulin superfamily member 23","Uniprot":["A1L1A6"],"Chromosome":"19","Position":"44613563-44636781","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"15.9","liver":"24.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"7.7","Enteroendocrine cells":"5.8","Hepatocytes":"14.7","Late spermatids":"11.9","Proximal enterocytes":"41.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"liver cancer":"12.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"2.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"2.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"6.7","Kidney cancer":"4.7"},"RNA tissue cell type enrichment":["Pancreas - Ductal cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051811"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA051811":"AB_2681621"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.20e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"}},{"Gene":"IGSF3","Gene synonym":["EWI-3","MGC117164","V8"],"Ensembl":"ENSG00000143061","Gene description":"Immunoglobulin superfamily member 3","Uniprot":["O75054"],"Chromosome":"1","Position":"116574399-116667755","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"38.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036305","HPA036306"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA036305":"AB_2675050","HPA036306":"AB_10671245"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.98e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.03e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.03e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.87e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"}},{"Gene":"IGSF5","Gene synonym":["JAM4"],"Ensembl":"ENSG00000183067","Gene description":"Immunoglobulin superfamily member 5","Uniprot":["Q9NSI5"],"Chromosome":"21","Position":"39745407-39802096","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"139.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Prostate - Prostate glandular cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057282"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA057282":"AB_2683395"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"}},{"Gene":"IGSF6","Gene synonym":["DORA"],"Ensembl":"ENSG00000140749","Gene description":"Immunoglobulin superfamily member 6","Uniprot":["O95976"],"Chromosome":"16","Position":"21639550-21652608","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"29.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Hofbauer cells":"264.5","Kupffer cells":"171.3","Langerhans cells":"199.4","Macrophages":"321.3","monocytes":"246.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1213.7"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"granulocytes":"1213.7"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Skin - Langerhans cells","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041023","HPA041072"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041023":"AB_10794434","HPA041072":"AB_10794262"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.92e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.54e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"}},{"Gene":"IGSF8","Gene synonym":["CD316","CD81P3","EWI2","PGRL"],"Ensembl":"ENSG00000162729","Gene description":"Immunoglobulin superfamily member 8","Uniprot":["Q969P0"],"Chromosome":"1","Position":"160091340-160098943","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"155.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"249.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011917","HPA075970"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA011917":"AB_1851536","HPA075970":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.32e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"}},{"Gene":"IGSF9","Gene synonym":["IGSF9A","KIAA1355","Nrt1"],"Ensembl":"ENSG00000085552","Gene description":"Immunoglobulin superfamily member 9","Uniprot":["Q9P2J2"],"Chromosome":"1","Position":"159927039-159945613","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"32.8","retina":"34.8","skin 1":"23.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"67.2","Distal enterocytes":"53.5","Gastric mucus-secreting cells":"32.2","Rod photoreceptor cells":"174.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enterocytes","Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"basal ganglia":"2.9","cerebellum":"5.5"},"Antibody":["HPA037753"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037753":"AB_10672915"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.16e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"}},{"Gene":"IGSF9B","Gene synonym":["KIAA1030","LINC00947","LOC283174","MIR4697HG"],"Ensembl":"ENSG00000080854","Gene description":"Immunoglobulin superfamily member 9B","Uniprot":["Q9UPX0"],"Chromosome":"11","Position":"133896438-133956968","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Neurogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"38.8","choroid plexus":"20.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"37.2","Excitatory neurons":"24.8","Horizontal cells":"80.8","Muller glia cells":"15.4","Oligodendrocyte precursor cells":"29.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"38.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"23.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010802"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Golgi apparatus","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA010802":"AB_1079194"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"}},{"Gene":"IKBIP","Gene synonym":["FLJ31051","IKIP"],"Ensembl":"ENSG00000166130","Gene description":"IKBKB interacting protein","Uniprot":["Q70UQ0"],"Chromosome":"12","Position":"98613405-98645113","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"84.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"28.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"28.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038677","HPA038678","HPA061541"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA038677":"AB_2676146","HPA038678":"AB_10672723","HPA061541":"AB_2684555"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.00e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.60e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"}},{"Gene":"IKZF1","Gene synonym":["hIk-1","Hs.54452","IKAROS","LyF-1","PPP1R92","ZNFN1A1"],"Ensembl":"ENSG00000185811","Gene description":"IKAROS family zinc finger 1","Uniprot":["Q13422"],"Chromosome":"7","Position":"50304068-50405101","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Cell cycle","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"bone marrow":"173.0","lymphoid tissue":"112.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"161.5","dendritic cells":"378.3","Langerhans cells":"115.3","monocytes":"150.7","NK-cells":"323.4","T-cells":"244.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"131","RNA cell line specific nTPM":{"Leukemia":"92.0","lymphoma":"124.9","Myeloma":"43.3"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Colon - T-cells","Skeletal muscle - Macrophages","Skin - T-cells","Stomach - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009247","HPA035221","HPA035222"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB009247":"AB_2124699","HPA035221":"AB_2674524","HPA035222":"AB_2674525"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.28e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.02e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.63e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"}},{"Gene":"IL10RA","Gene synonym":["CD210","CD210a","CDW210A","HIL-10R","IL10R"],"Ensembl":"ENSG00000110324","Gene description":"Interleukin 10 receptor subunit alpha","Uniprot":["Q13651"],"Chromosome":"11","Position":"117986370-118003037","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"63.6","lymphoid tissue":"73.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"87.4","Extravillous trophoblasts":"106.4","Hofbauer cells":"92.7","Kupffer cells":"118.2","Langerhans cells":"183.8","Macrophages":"134.4","monocytes":"211.2","NK-cells":"106.2","Plasma cells":"95.8","T-cells":"109.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"29.8","Myeloma":"16.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Skeletal muscle - Macrophages","Skin - T-cells","Stomach - Macrophages","Testis - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065647","HPA069086"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA065647":null,"HPA069086":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.47e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"}},{"Gene":"IL10RB","Gene synonym":["CDW210B","CRF2-4","CRFB4","D21S58","D21S66","IL-10R2"],"Ensembl":"ENSG00000243646","Gene description":"Interleukin 10 receptor subunit beta","Uniprot":["Q08334"],"Chromosome":"21","Position":"33266367-33310187","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Antiviral defense"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"44.7","Paneth cells":"44.3","Proximal enterocytes":"55.2","Syncytiotrophoblasts":"53.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020670","HPA047550"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB020670":null,"HPA047550":"AB_2680086"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.62e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"IL11RA","Gene synonym":[],"Ensembl":"ENSG00000137070","Gene description":"Interleukin 11 receptor subunit alpha","Uniprot":["Q14626"],"Chromosome":"9","Position":"34650702-34661902","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Craniosynostosis","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"49.9","Granulosa cells":"60.2","Late spermatids":"99.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"41.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013162","CAB032830","HPA036652"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB032830":"AB_2123745","HPA013162":"AB_2668790","HPA036652":"AB_2675229"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.56e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"}},{"Gene":"IL12A","Gene synonym":["CLMF","IL-12A","NFSK","NKSF1","p35"],"Ensembl":"ENSG00000168811","Gene description":"Interleukin 12A","Uniprot":["P29459"],"Chromosome":"3","Position":"159988835-159996019","Protein class":["Cancer-related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Cytokine","Growth factor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"4.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"3.6","Oligodendrocyte precursor cells":"3.9","Plasma cells":"3.3","Respiratory ciliated cells":"2.9","Schwann cells":"4.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"2.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"2.8"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001886"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001886":"AB_1079132"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"}},{"Gene":"IL12RB1","Gene synonym":["CD212","IL12RB"],"Ensembl":"ENSG00000096996","Gene description":"Interleukin 12 receptor subunit beta 1","Uniprot":["P42701"],"Chromosome":"19","Position":"18058995-18098944","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"24.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"10.7","monocytes":"34.1","NK-cells":"55.5","Plasma cells":"12.1","T-cells":"26.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"Leukemia":"9.3","lymphoma":"22.4","Myeloma":"27.4"},"RNA tissue cell type enrichment":["Breast - T-cells","Lung - T-cells","Prostate - T-cells","Skeletal muscle - Macrophages","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074414"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA074414":"AB_2686687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.41e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.90e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"}},{"Gene":"IL12RB2","Gene synonym":[],"Ensembl":"ENSG00000081985","Gene description":"Interleukin 12 receptor subunit beta 2","Uniprot":["Q99665"],"Chromosome":"1","Position":"67307364-67398724","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.5","placenta":"7.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Erythroid cells":"5.8","Excitatory neurons":"22.2","Hofbauer cells":"8.9","Inhibitory neurons":"16.1","Melanocytes":"8.7","NK-cells":"18.3","T-cells":"15.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"1.8","head and neck cancer":"2.5","melanoma":"5.6","renal cancer":"1.7"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"4.5"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"21.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"35","RNA blood lineage specific nTPM":{"NK-cells":"21.3","T-cells":"6.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"4.4","skin cancer":"6.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024168"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA024168":"AB_1851629"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"}},{"Gene":"IL13RA1","Gene synonym":["CD213a1","IL-13Ra","NR4"],"Ensembl":"ENSG00000131724","Gene description":"Interleukin 13 receptor subunit alpha 1","Uniprot":["P78552"],"Chromosome":"X","Position":"118727133-118794535","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"183.6","Macrophages":"149.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"10.9","eosinophil":"12.2","myeloid DC":"17.2","neutrophil":"29.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"17.2","granulocytes":"29.2","monocytes":"10.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.19e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"}},{"Gene":"IL13RA2","Gene synonym":["CD213a2","CT19","IL-13R","IL13BP"],"Ensembl":"ENSG00000123496","Gene description":"Interleukin 13 receptor subunit alpha 2","Uniprot":["Q14627"],"Chromosome":"X","Position":"115003975-115019977","Protein class":["Cancer-related genes","CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"12.0","testis":"30.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"318.3","Late spermatids":"111.5","Spermatocytes":"66.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"17.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"83.1","skin cancer":"86.3"},"RNA tissue cell type enrichment":["Liver - Sinusoid Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"7.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045831","HPA067363"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA045831":null,"HPA067363":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.55e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"}},{"Gene":"IL15RA","Gene synonym":["CD215","IL-15RA"],"Ensembl":"ENSG00000134470","Gene description":"Interleukin 15 receptor subunit alpha","Uniprot":["Q13261"],"Chromosome":"10","Position":"5943639-5978187","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"35.6","Exocrine glandular cells":"33.8","Fibroblasts":"31.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"cerebellum":"7.1"},"Antibody":["CAB026215"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026215":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.67e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.35e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.27e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"}},{"Gene":"IL17RA","Gene synonym":["CD217","CDw217","hIL-17R","IL-17RA","IL17R"],"Ensembl":"ENSG00000177663","Gene description":"Interleukin 17 receptor A","Uniprot":["Q96F46"],"Chromosome":"22","Position":"17084954-17115694","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"31.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"79.1","Kupffer cells":"122.0","Macrophages":"74.5","monocytes":"80.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"16.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Macrophages","Lung - Neutrophil_2","Skin - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB024996"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"62000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB024996":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.35e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-3"}},{"Gene":"IL17RB","Gene synonym":["CRL4","EVI27","IL17BR","IL17RH1"],"Ensembl":"ENSG00000056736","Gene description":"Interleukin 17 receptor B","Uniprot":["Q9NRM6"],"Chromosome":"3","Position":"53846568-53865794","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"28.9","kidney":"59.8","liver":"33.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"46.8","Oligodendrocyte precursor cells":"36.1","Proximal tubular cells":"83.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Kidney - Proximal tubular cells","Prostate - Prostate basal glandular cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005482"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA005482":"AB_1234567"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.61e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-3"}},{"Gene":"IL17RC","Gene synonym":["IL17-RL"],"Ensembl":"ENSG00000163702","Gene description":"Interleukin 17 receptor C","Uniprot":["Q8NAC3"],"Chromosome":"3","Position":"9917074-9933630","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Inflammatory response"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"52.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.7","myeloid DC":"2.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"dendritic cells":"2.1","monocytes":"1.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019885","CAB026255"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026255":null,"HPA019885":"AB_1851664"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.38e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"}},{"Gene":"IL17RD","Gene synonym":["FLJ35755","IL-17RD","IL17RLM","SEF"],"Ensembl":"ENSG00000144730","Gene description":"Interleukin 17 receptor D","Uniprot":["Q8NFM7"],"Chromosome":"3","Position":"57089982-57170306","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism","Kallmann syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"28.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"15.7","Early spermatids":"15.4","Late spermatids":"22.8","Microglial cells":"14.6","Peritubular cells":"24.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"13.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Liver - Hepatic stellate cells","Lung - Fibroblast_2","Prostate - Smooth muscle cells","Skeletal muscle - Fibroblasts","Testis - Early spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039577","HPA043550"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA039577":"AB_2676580","HPA043550":"AB_2678546"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.92e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-3"}},{"Gene":"IL17RE","Gene synonym":["FLJ23658"],"Ensembl":"ENSG00000163701","Gene description":"Interleukin 17 receptor E","Uniprot":["Q8NFR9"],"Chromosome":"3","Position":"9902612-9916402","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Inflammatory response"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"20.8","skin 1":"31.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"63.6","Enteroendocrine cells":"37.5","Gastric mucus-secreting cells":"50.1","Intestinal goblet cells":"62.3","Paneth cells":"42.4","Proximal enterocytes":"68.2","Undifferentiated cells":"35.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"1.5"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019011"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019011":"AB_1851667"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"}},{"Gene":"IL18R1","Gene synonym":["CD218a","IL-1Rrp","IL1RRP"],"Ensembl":"ENSG00000115604","Gene description":"Interleukin 18 receptor 1","Uniprot":["Q13478"],"Chromosome":"2","Position":"102311529-102398777","Protein class":["CD markers","Enzymes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Inflammatory response"],"Molecular function":["Hydrolase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"24.2","lymphoid tissue":"18.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"38.2","dendritic cells":"56.2","granulocytes":"92.9","Langerhans cells":"33.2","NK-cells":"47.8","Schwann cells":"26.6","T-cells":"32.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"45.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007615"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA007615":"AB_1851675"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.52e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"}},{"Gene":"IL18RAP","Gene synonym":["AcPL","CD218b"],"Ensembl":"ENSG00000115607","Gene description":"Interleukin 18 receptor accessory protein","Uniprot":["O95256"],"Chromosome":"2","Position":"102418689-102452565","Protein class":["CD markers","Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Inflammatory response"],"Molecular function":["Hydrolase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"104.6","lymphoid tissue":"46.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"NK-cells":"76.3","T-cells":"19.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"118.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"107","RNA blood lineage specific nTPM":{"granulocytes":"67.6","NK-cells":"118.1","T-cells":"65.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"18","RNA cell line specific nTPM":{"Leukemia":"2.4","lymphoma":"2.1"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Lung - Neutrophil_2","Skeletal muscle - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025270"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025270":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"}},{"Gene":"IL1R1","Gene synonym":["CD121A","D2S1473","IL1R","IL1RA"],"Ensembl":"ENSG00000115594","Gene description":"Interleukin 1 receptor type 1","Uniprot":["P14778"],"Chromosome":"2","Position":"102064544-102179874","Protein class":["Cancer-related genes","CD markers","Enzymes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Inflammatory response"],"Molecular function":["Hydrolase","Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"308.6","Glandular and luminal cells":"316.8","Langerhans cells":"224.1","Prostatic glandular cells":"296.8","Thymic epithelial cells":"249.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001237","HPA005823","CAB007779","HPA029560"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"CAB007779":"AB_562073","HPA001237":null,"HPA005823":"AB_2667445","HPA029560":"AB_2673094"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.92e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"}},{"Gene":"IL1R2","Gene synonym":["CD121b","IL1RB"],"Ensembl":"ENSG00000115590","Gene description":"Interleukin 1 receptor type 2","Uniprot":["P27930"],"Chromosome":"2","Position":"101991960-102028544","Protein class":["Cancer-related genes","CD markers","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"90.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"297.0","Kupffer cells":"424.8","Langerhans cells":"1486.7","Macrophages":"209.6","Schwann cells":"295.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"16.1"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"6.4","pons":"1.9"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"26","RNA blood cell specific nTPM":{"neutrophil":"377.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"granulocytes":"377.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"57.0"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Lung - Neutrophil_2","Prostate - Macrophages","Skeletal muscle - Neutrophils"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027597","HPA027598"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":7130000,"Blood concentration - Conc. blood MS [pg\/L]":"27000000","Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027597":"AB_10600768","HPA027598":"AB_10601229"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.58e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"}},{"Gene":"IL1RAP","Gene synonym":["C3orf13","IL-1RAcP","IL1R3"],"Ensembl":"ENSG00000196083","Gene description":"Interleukin 1 receptor accessory protein","Uniprot":["Q9NPH3"],"Chromosome":"3","Position":"190514051-190659750","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Hydrolase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"225.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"126.5","Hepatocytes":"319.3","Oligodendrocyte precursor cells":"285.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"eosinophil":"23.8","neutrophil":"95.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"granulocytes":"95.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035293"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"350000000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035293":"AB_10671511"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.31e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.16e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.29e-4"}},{"Gene":"IL1RAPL1","Gene synonym":["IL1R8","IL1RAPL","MRX10","MRX21","MRX34","OPHN4","TIGIRR-2"],"Ensembl":"ENSG00000169306","Gene description":"Interleukin 1 receptor accessory protein like 1","Uniprot":["Q9NZN1"],"Chromosome":"X","Position":"28587446-29956718","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Receptor"],"Disease involvement":["Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"73","RNA tissue specific nTPM":{"brain":"33.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1297.1","Inhibitory neurons":"2541.4","Oligodendrocyte precursor cells":"1871.5","Oligodendrocytes":"6061.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"white matter":"33.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"skin cancer":"6.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-3"}},{"Gene":"IL1RAPL2","Gene synonym":["IL-1R9","IL1R9","IL1RAPL-2","TIGIRR-1"],"Ensembl":"ENSG00000189108","Gene description":"Interleukin 1 receptor accessory protein like 2","Uniprot":["Q9NP60"],"Chromosome":"X","Position":"104566199-105767829","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"1.4","parathyroid gland":"1.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Excitatory neurons":"188.6","Inhibitory neurons":"114.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"1.0"},"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-5"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"}},{"Gene":"IL1RL1","Gene synonym":["DER4","FIT-1","IL33R","ST2","ST2L","ST2V","T1"],"Ensembl":"ENSG00000115602","Gene description":"Interleukin 1 receptor like 1","Uniprot":["Q01638"],"Chromosome":"2","Position":"102311502-102352037","Protein class":["Candidate cardiovascular disease genes","Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"kidney":"126.4","lung":"162.0","placenta":"199.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"159.6","Endothelial cells":"115.0","granulocytes":"625.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"7.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"64","RNA blood cell specific nTPM":{"basophil":"38.3","eosinophil":"29.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"72","RNA blood lineage specific nTPM":{"granulocytes":"38.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Esophageal cancer":"23.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007406","HPA007917"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Focal adhesion sites","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":19100000,"Blood concentration - Conc. blood MS [pg\/L]":"3100000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Focal adhesion sites","Cytosol"],"Antibody RRID":{"HPA007406":"AB_1079128","HPA007917":"AB_1079129"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"}},{"Gene":"IL1RL2","Gene synonym":["IL1R-rp2","IL1RRP2"],"Ensembl":"ENSG00000115598","Gene description":"Interleukin 1 receptor like 2","Uniprot":["Q9HB29"],"Chromosome":"2","Position":"102187006-102240002","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Hydrolase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"12.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"6.2","Excitatory neurons":"9.6","Glandular and luminal cells":"6.7","Langerhans cells":"7.9","Suprabasal keratinocytes":"6.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"1.0"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"}},{"Gene":"IL20RA","Gene synonym":["IL-20R1","ZCYTOR7"],"Ensembl":"ENSG00000016402","Gene description":"Interleukin 20 receptor subunit alpha","Uniprot":["Q9UHF4"],"Chromosome":"6","Position":"136999971-137045180","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"26.4","skin 1":"37.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"57.4","Endometrial ciliated cells":"105.4","Glandular and luminal cells":"72.8","Muller glia cells":"50.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"16.8"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB024990","HPA042281"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB024990":null,"HPA042281":"AB_10806235"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.43e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.29e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"}},{"Gene":"IL20RB","Gene synonym":["DIRS1","FNDC6","IL-20R2","MGC34923"],"Ensembl":"ENSG00000174564","Gene description":"Interleukin 20 receptor subunit beta","Uniprot":["Q6UXL0"],"Chromosome":"3","Position":"136946230-137011085","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"110.7","skin 1":"163.3","vagina":"66.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Basal keratinocytes":"58.6","Basal respiratory cells":"113.8","Basal squamous epithelial cells":"53.5","Club cells":"30.1","Early spermatids":"65.4","Ionocytes":"46.7","Late spermatids":"32.6","Squamous epithelial cells":"58.9","Suprabasal keratinocytes":"103.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"cervical cancer":"54.5","head and neck cancer":"50.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"90.8","head and neck cancer":"92.5"},"RNA tissue cell type enrichment":["Prostate - Urothelial cells","Skin - Keratinocyte (other)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063914"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA063914":"AB_2732709"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.44e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"}},{"Gene":"IL21R","Gene synonym":["CD360"],"Ensembl":"ENSG00000103522","Gene description":"Interleukin 21 receptor","Uniprot":["Q9HBE5"],"Chromosome":"16","Position":"27402174-27452042","Protein class":["Cancer-related genes","CD markers","Disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"7.6","lymphoid tissue":"24.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"12.3","Hofbauer cells":"7.7","Langerhans cells":"19.5","monocytes":"11.5","NK-cells":"29.6","T-cells":"24.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"46.5","Myeloma":"25.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042296"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042296":"AB_10806236"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.29e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-6"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"}},{"Gene":"IL22RA1","Gene synonym":["CRF2-9","IL22R"],"Ensembl":"ENSG00000142677","Gene description":"Interleukin 22 receptor subunit alpha 1","Uniprot":["Q8N6P7"],"Chromosome":"1","Position":"24119771-24143140","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"pancreas":"199.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"16.4","Intestinal goblet cells":"15.8","Proximal enterocytes":"36.3","Respiratory ciliated cells":"14.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"10.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enterocytes","Kidney - Proximal tubular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 20: Airway & Pancreas - Proteolysis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"}},{"Gene":"IL22RA2","Gene synonym":["CRF2-S1","IL-22BP"],"Ensembl":"ENSG00000164485","Gene description":"Interleukin 22 receptor subunit alpha 2","Uniprot":["Q969J5"],"Chromosome":"6","Position":"137143820-137173648","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"breast":"3.6","lymphoid tissue":"3.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"8.8","Breast myoepithelial cells":"3.6","Macrophages":"1.0","Syncytiotrophoblasts":"1.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030582","CAB034906"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":40500000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034906":"AB_2124501","HPA030582":"AB_10600716"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"}},{"Gene":"IL23R","Gene synonym":["IL-23R"],"Ensembl":"ENSG00000162594","Gene description":"Interleukin 23 receptor","Uniprot":["Q5VWK5"],"Chromosome":"1","Position":"67138907-67259979","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"1.6","testis":"1.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"11.5","Late spermatids":"7.5","T-cells":"3.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"MAIT T-cell":"21.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"29","RNA blood lineage specific nTPM":{"T-cells":"21.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Leukemia":"3.1","lymphoma":"2.8","Myeloma":"1.2","Sarcoma":"1.0"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Breast - T-cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056427"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056427":"AB_2683129"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-3"}},{"Gene":"IL27RA","Gene synonym":["CRL1","IL-27R","TCCR","WSX-1","WSX1","zcytor1"],"Ensembl":"ENSG00000104998","Gene description":"Interleukin 27 receptor subunit alpha","Uniprot":["Q6UWB1"],"Chromosome":"19","Position":"14031762-14053218","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"16.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"43.7","Kupffer cells":"47.9","Langerhans cells":"64.2","monocytes":"35.5","NK-cells":"56.9","T-cells":"60.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Heart muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073441"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4900000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA073441":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.74e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.58e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"}},{"Gene":"IL2RA","Gene synonym":["CD25","IDDM10","IL2R"],"Ensembl":"ENSG00000134460","Gene description":"Interleukin 2 receptor subunit alpha","Uniprot":["P01589"],"Chromosome":"10","Position":"6010689-6062370","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"18.9","lymphoid tissue":"17.4","urinary bladder":"11.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"12.3","Langerhans cells":"5.4","Macrophages":"14.8","NK-cells":"12.5","T-cells":"24.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"175.9","T-reg":"248.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"granulocytes":"175.9","T-cells":"248.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"30","RNA cell line specific nTPM":{"lymphoma":"140.9"},"RNA tissue cell type enrichment":["Heart muscle - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002419","HPA054622"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"410000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002419":"AB_563538","HPA054622":"AB_2682546"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.08e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"}},{"Gene":"IL2RB","Gene synonym":["CD122","IL15RB"],"Ensembl":"ENSG00000100385","Gene description":"Interleukin 2 receptor subunit beta","Uniprot":["P14784"],"Chromosome":"22","Position":"37125843-37175054","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"36.8","lymphoid tissue":"50.2","placenta":"36.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"97.8","NK-cells":"304.7","T-cells":"98.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"gdT-cell":"50.8","NK-cell":"186.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"NK-cells":"186.4","T-cells":"50.8"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"lymphoma":"85.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - NK-cells (Liver)","Pancreas - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"basal ganglia":"1.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062657"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062657":"AB_2684822"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.76e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.18e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.50e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"}},{"Gene":"IL2RG","Gene synonym":["CD132","CIDX","IMD4","SCIDX1"],"Ensembl":"ENSG00000147168","Gene description":"Interleukin 2 receptor subunit gamma","Uniprot":["P31785"],"Chromosome":"X","Position":"71107404-71112108","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"118.0","lymphoid tissue":"346.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"112.9","dendritic cells":"93.7","Distal enterocytes":"87.2","Langerhans cells":"151.6","NK-cells":"284.8","Plasma cells":"91.0","Proximal enterocytes":"80.8","T-cells":"197.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Leukemia":"203.1","lymphoma":"129.5","Myeloma":"347.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Colon - T-cells","Kidney - T-cells","Liver - T-cells","Pancreas - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046641"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA046641":"AB_2679733"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.28e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"}},{"Gene":"IL31RA","Gene synonym":["CRL","CRL3","GLM-R","Glmr","IL-31RA"],"Ensembl":"ENSG00000164509","Gene description":"Interleukin 31 receptor A","Uniprot":["Q8NI17"],"Chromosome":"5","Position":"55851357-55922854","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Amyloidosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1.6","lymphoid tissue":"2.1","testis":"1.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1.5","granulocytes":"1.6","Late spermatids":"1.6","Prostatic glandular cells":"2.2","Spermatocytes":"2.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"0.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skin - Outer root sheath cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebral cortex":"1.2"},"Antibody":["HPA051532","HPA068114"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA051532":null,"HPA068114":"AB_2732779"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"}},{"Gene":"IL3RA","Gene synonym":["CD123"],"Ensembl":"ENSG00000185291","Gene description":"Interleukin 3 receptor subunit alpha","Uniprot":["P26951"],"Chromosome":"X","Position":"1336616-1382689","Protein class":["CD markers","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"dendritic cells":"473.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"2665.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2665.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"20.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003539","CAB018374"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB018374":"AB_2233620","HPA003539":"AB_1078438"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.78e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.27e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"}},{"Gene":"IL4I1","Gene synonym":["FIG1"],"Ensembl":"ENSG00000104951","Gene description":"Interleukin 4 induced 1","Uniprot":["Q96RQ9"],"Chromosome":"19","Position":"49889654-49929539","Protein class":["Enzymes","Metabolic proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"18.3","testis":"26.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Langerhans cells":"461.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"35.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"103.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"monocytes":"36.8","T-cells":"103.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"33.8"},"RNA tissue cell type enrichment":["Breast - T-cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045598"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA045598":"AB_10969138"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"}},{"Gene":"IL4R","Gene synonym":["CD124"],"Ensembl":"ENSG00000077238","Gene description":"Interleukin 4 receptor","Uniprot":["P24394"],"Chromosome":"16","Position":"27313668-27364778","Protein class":["Cancer-related genes","CD markers","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"72.7","granulocytes":"92.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"78.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"78.1","granulocytes":"31.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"135.3"},"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004451","HPA050124","HPA070380"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Centriolar satellite"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":38500,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"CAB004451":"AB_626889","HPA050124":"AB_2681026","HPA070380":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.43e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"}},{"Gene":"IL5RA","Gene synonym":["CD125","CDw125","IL5R"],"Ensembl":"ENSG00000091181","Gene description":"Interleukin 5 receptor subunit alpha","Uniprot":["Q01344"],"Chromosome":"3","Position":"3066324-3126613","Protein class":["CD markers","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"9.0","fallopian tube":"10.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"28.2","granulocytes":"25.9","Plasma cells":"16.1","Respiratory ciliated cells":"25.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"192","RNA blood cell specific nTPM":{"basophil":"178.4","eosinophil":"355.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"255","RNA blood lineage specific nTPM":{"granulocytes":"355.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"3.4","Myeloma":"8.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Colon - Mast cells","Lung - Respiratory ciliated cells","Prostate - Prostate glandular cells","Skin - Mast cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"910000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"}},{"Gene":"IL6R","Gene synonym":["CD126"],"Ensembl":"ENSG00000160712","Gene description":"Interleukin 6 receptor","Uniprot":["P08887"],"Chromosome":"1","Position":"154405193-154469450","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"58.3","skeletal muscle":"94.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"87.2","Langerhans cells":"92.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"88.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"82.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":24800000,"Blood concentration - Conc. blood MS [pg\/L]":"35000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.65e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"IL6ST","Gene synonym":["CD130","GP130","sGP130"],"Ensembl":"ENSG00000134352","Gene description":"Interleukin 6 signal transducer","Uniprot":["P40189"],"Chromosome":"5","Position":"55935095-55995022","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"698.7","Thymic epithelial cells":"420.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"16.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"16.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010558","CAB025784"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB025784":null,"HPA010558":"AB_1078439"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"IL7R","Gene synonym":["CD127","IL7RA"],"Ensembl":"ENSG00000168685","Gene description":"Interleukin 7 receptor","Uniprot":["P16871"],"Chromosome":"5","Position":"35852695-35879603","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"183.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"204.9","Serous glandular cells":"318.6","T-cells":"1261.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"102.1","MAIT T-cell":"369.5","memory CD4 T-cell":"213.8","memory CD8 T-cell":"151.1","naive CD4 T-cell":"179.5","naive CD8 T-cell":"124.6","NK-cell":"113.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"NK-cells":"113.2","T-cells":"369.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Colon - T-cells","Prostate - T-cells","Skin - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010215","HPA067550"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"610000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010215":"AB_673727","HPA067550":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"}},{"Gene":"IL9R","Gene synonym":["CD129"],"Ensembl":"ENSG00000124334","Gene description":"Interleukin 9 receptor","Uniprot":["Q01113"],"Chromosome":"X","Position":"155997581-156010817","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"3.4","urinary bladder":"4.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1.0","T-cells":"2.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"0.7","urothelial cancer":"1.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"3.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"B-cells":"1.8","granulocytes":"3.4","T-cells":"1.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Leukemia":"19.0","lymphoma":"18.9"},"RNA tissue cell type enrichment":["Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063240","HPA064557"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063240":"AB_2732700","HPA064557":"AB_2732716"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.90e-7"}},{"Gene":"ILDR1","Gene synonym":["DFNB42","MGC50831"],"Ensembl":"ENSG00000145103","Gene description":"Immunoglobulin like domain containing receptor 1","Uniprot":["Q86SU0"],"Chromosome":"3","Position":"121987323-122022247","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"15.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"13.7","Collecting duct cells":"11.8","Cytotrophoblasts":"15.8","Distal enterocytes":"17.3","Glandular and luminal cells":"14.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"1.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"12.1"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Alveolar cells type 2","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018207"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018207":"AB_1851742"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.79e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"}},{"Gene":"ILDR2","Gene synonym":["C1orf32"],"Ensembl":"ENSG00000143195","Gene description":"Immunoglobulin like domain containing receptor 2","Uniprot":["Q71H61"],"Chromosome":"1","Position":"166895711-166975540","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"12.8","retina":"10.6","testis":"8.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"22.1","Excitatory neurons":"44.3","Muller glia cells":"75.5","Oligodendrocyte precursor cells":"91.9","Sertoli cells":"22.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"4.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"4.6"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Prostate - Smooth muscle cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012545","HPA012815"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA012545":"AB_2126894","HPA012815":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"ILVBL","Gene synonym":["209L8","AHAS","FLJ39061","HACL1L","ILV2H","MGC1269","MGC19535"],"Ensembl":"ENSG00000105135","Gene description":"IlvB acetolactate synthase like","Uniprot":["A1L0T0"],"Chromosome":"19","Position":"15114984-15125786","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"165.9","Syncytiotrophoblasts":"322.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067682"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA067682":"AB_2685885"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.91e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"}},{"Gene":"IMMT","Gene synonym":["HMP","Mic60","MICOS60","MINOS2","P87","P89"],"Ensembl":"ENSG00000132305","Gene description":"Inner membrane mitochondrial protein","Uniprot":["Q16891"],"Chromosome":"2","Position":"86143932-86195472","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"288.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"288.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022439","HPA036164","HPA036165"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB022439":null,"HPA036164":"AB_2674979","HPA036165":"AB_2674980"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.03e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.51e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"}},{"Gene":"IMPA1","Gene synonym":["IMPA"],"Ensembl":"ENSG00000133731","Gene description":"Inositol monophosphatase 1","Uniprot":["P29218"],"Chromosome":"8","Position":"81656914-81686331","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037489"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"310000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037489":"AB_10671757"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"}},{"Gene":"IMPDH1","Gene synonym":["LCA11","RP10","sWSS2608"],"Ensembl":"ENSG00000106348","Gene description":"Inosine monophosphate dehydrogenase 1","Uniprot":["P20839"],"Chromosome":"7","Position":"128392277-128410252","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["GMP biosynthesis","Purine biosynthesis"],"Molecular function":["DNA-binding","Oxidoreductase","RNA-binding"],"Disease involvement":["Disease variant","FDA approved drug targets","Leber congenital amaurosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"106.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"168.7","Cone photoreceptor cells":"177.5","Rod photoreceptor cells":"190.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"89.1","eosinophil":"89.1","intermediate monocyte":"104.5","myeloid DC":"59.9","neutrophil":"197.5","non-classical monocyte":"135.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"59.9","granulocytes":"197.5","monocytes":"135.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001400"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":["Rods & Rings"],"Antibody RRID":{"HPA001400":"AB_1079139"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.87e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.31e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.78e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.72e-5"}},{"Gene":"IMPDH2","Gene synonym":[],"Ensembl":"ENSG00000178035","Gene description":"Inosine monophosphate dehydrogenase 2","Uniprot":["P12268"],"Chromosome":"3","Position":"49024325-49029447","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["GMP biosynthesis","Purine biosynthesis"],"Molecular function":["DNA-binding","Oxidoreductase","RNA-binding"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001400","CAB020717"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"340000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Rods & Rings"],"Antibody RRID":{"CAB020717":null,"HPA001400":"AB_1079139"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.22e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"}},{"Gene":"IMPG2","Gene synonym":["IPM200","RP56","SPACRCAN"],"Ensembl":"ENSG00000081148","Gene description":"Interphotoreceptor matrix proteoglycan 2","Uniprot":["Q9BZV3"],"Chromosome":"3","Position":"101222546-101320575","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Heparin-binding","Receptor"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"retina":"305.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"649.7","Rod photoreceptor cells":"341.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"ovarian cancer":"2.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Brain cancer":"2.8","lung cancer":"1.6","Uterine cancer":"3.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008779","HPA015907"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008779":"AB_2668138","HPA015907":"AB_2669323"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"}},{"Gene":"INAFM1","Gene synonym":["PRR24"],"Ensembl":"ENSG00000257704","Gene description":"InaF motif containing 1","Uniprot":["C9JVW0"],"Chromosome":"19","Position":"47274885-47275723","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"108.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"58.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064015"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064015":"AB_2685177"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.20e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.04e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-3"}},{"Gene":"INAFM2","Gene synonym":["LINC00984","OGU1"],"Ensembl":"ENSG00000259330","Gene description":"InaF motif containing 2","Uniprot":["P0DMQ5"],"Chromosome":"15","Position":"40323692-40326715","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"71.7","Early spermatids":"35.7","Spermatocytes":"28.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"2.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"1.1","granulocytes":"2.6","monocytes":"1.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.87e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.88e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"}},{"Gene":"ING1","Gene synonym":["p24ING1c","p33","p33ING1","p33ING1b","p47","p47ING1a"],"Ensembl":"ENSG00000153487","Gene description":"Inhibitor of growth family member 1","Uniprot":["Q9UK53"],"Chromosome":"13","Position":"110712736-110723339","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"242.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016136","CAB017773","HPA052591"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016136":"AB_628077","CAB017773":null,"HPA052591":"AB_2681876"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.81e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"}},{"Gene":"INIP","Gene synonym":["C9orf80","HSPC043","hSSBIP1","MISE","SOSS-C"],"Ensembl":"ENSG00000148153","Gene description":"INTS3 and NABP interacting protein","Uniprot":["Q9NRY2"],"Chromosome":"9","Position":"112683926-112718149","Protein class":["Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020382"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA020382":"AB_1845840"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.08e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.00e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.53e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"}},{"Gene":"INO80C","Gene synonym":["C18orf37","FLJ38183","hIes6","IES6"],"Ensembl":"ENSG00000153391","Gene description":"INO80 complex subunit C","Uniprot":["Q6PI98"],"Chromosome":"18","Position":"35452230-35497979","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA recombination","DNA repair","Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"197.9","Extravillous trophoblasts":"120.4","Spermatocytes":"172.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049060"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA049060":"AB_2680617"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.58e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.62e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"}},{"Gene":"INPP1","Gene synonym":[],"Ensembl":"ENSG00000151689","Gene description":"Inositol polyphosphate-1-phosphatase","Uniprot":["P49441"],"Chromosome":"2","Position":"190343570-190371665","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"497.7","Late spermatids":"933.6","Squamous epithelial cells":"179.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"96.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"96.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Lung - Endothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036698","HPA036699"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"31000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA036698":"AB_10672226","HPA036699":"AB_2675260"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.70e-4"}},{"Gene":"INPP4A","Gene synonym":["INPP4"],"Ensembl":"ENSG00000040933","Gene description":"Inositol polyphosphate-4-phosphatase type I A","Uniprot":["Q96PE3"],"Chromosome":"2","Position":"98444854-98594392","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"155.1","Excitatory neurons":"148.3","Inhibitory neurons":"121.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"70.2"},"RNA tissue cell type enrichment":["Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001628"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA001628":"AB_10961254"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.70e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"}},{"Gene":"INPP4B","Gene synonym":[],"Ensembl":"ENSG00000109452","Gene description":"Inositol polyphosphate-4-phosphatase type II B","Uniprot":["O15327"],"Chromosome":"4","Position":"142023160-142847432","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"153.7","Early spermatids":"149.2","Excitatory neurons":"193.3","Inhibitory neurons":"601.4","Late spermatids":"295.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory CD4 T-cell":"30.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037681","HPA037682"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA037681":"AB_10670389","HPA037682":"AB_10671377"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"}},{"Gene":"INPP5F","Gene synonym":["hSac2","KIAA0966","SAC2"],"Ensembl":"ENSG00000198825","Gene description":"Inositol polyphosphate-5-phosphatase F","Uniprot":["Q9Y2H2"],"Chromosome":"10","Position":"119726042-119829147","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"135.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"78.3","Inhibitory neurons":"127.4","Late spermatids":"92.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"27.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"skin cancer":"72.2","testis cancer":"181.5"},"RNA tissue cell type enrichment":["Prostate - Fibroblasts","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042605"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042605":"AB_10793886"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"}},{"Gene":"INPP5J","Gene synonym":["INPP5","PIB5PA","PIPP"],"Ensembl":"ENSG00000185133","Gene description":"Inositol polyphosphate-5-phosphatase J","Uniprot":["Q15735"],"Chromosome":"22","Position":"31122731-31134697","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"parathyroid gland":"123.2","thyroid gland":"204.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"17.7","Distal enterocytes":"30.6","Inhibitory neurons":"19.2","Muller glia cells":"22.1","Paneth cells":"17.2","Proximal enterocytes":"60.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"thyroid cancer":"63.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"12.7"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 2","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes","Stomach - Chief cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"131.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034539"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA034539":"AB_10670974"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.47e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"}},{"Gene":"INPPL1","Gene synonym":["SHIP2"],"Ensembl":"ENSG00000165458","Gene description":"Inositol polyphosphate phosphatase like 1","Uniprot":["O15357"],"Chromosome":"11","Position":"72223701-72239147","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell adhesion","Immunity","Lipid metabolism"],"Molecular function":["Actin-binding","Hydrolase"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037601"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA037601":"AB_10672281"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.37e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"}},{"Gene":"INSIG1","Gene synonym":["CL-6","MGC1405"],"Ensembl":"ENSG00000186480","Gene description":"Insulin induced gene 1","Uniprot":["O15503"],"Chromosome":"7","Position":"155297776-155310235","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"563.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Langerhans cells":"5156.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"142.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"intermediate monocyte":"272.8","non-classical monocyte":"500.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"monocytes":"500.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071524"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA071524":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.62e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"}},{"Gene":"INSIG2","Gene synonym":[],"Ensembl":"ENSG00000125629","Gene description":"Insulin induced gene 2","Uniprot":["Q9Y5U4"],"Chromosome":"2","Position":"118088452-118110997","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033861"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033861":"AB_2249149"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.10e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.19e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.11e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"}},{"Gene":"INSR","Gene synonym":["CD220"],"Ensembl":"ENSG00000171105","Gene description":"Insulin receptor","Uniprot":["P06213"],"Chromosome":"19","Position":"7112255-7294414","Protein class":["CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Diabetes mellitus","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"9.8","granulocytes":"5.9","monocytes":"12.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"22.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036302","HPA036303"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA036302":"AB_2675048","HPA036303":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"}},{"Gene":"INSRR","Gene synonym":["IRR"],"Ensembl":"ENSG00000027644","Gene description":"Insulin receptor related receptor","Uniprot":["P14616"],"Chromosome":"1","Position":"156840063-156859117","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"14.5","kidney":"3.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.2","Collecting duct cells":"2.0","Horizontal cells":"1.9","Late spermatids":"1.6","Sertoli cells":"2.8","Spermatocytes":"6.3","Spermatogonia":"1.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"medulla oblongata":"14.5","pons":"13.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"Neuroblastoma":"7.2"},"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025285"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA025285":"AB_1851814"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"}},{"Gene":"INTS1","Gene synonym":["DKFZp586J0619","INT1","KIAA1440","NET28"],"Ensembl":"ENSG00000164880","Gene description":"Integrator complex subunit 1","Uniprot":["Q8N201"],"Chromosome":"7","Position":"1470277-1504389","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021658","HPA053009"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA021658":"AB_1852402","HPA053009":"AB_2682016"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.66e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.83e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"}},{"Gene":"INTS10","Gene synonym":["C8orf35","FLJ10569","INT10"],"Ensembl":"ENSG00000104613","Gene description":"Integrator complex subunit 10","Uniprot":["Q9NVR2"],"Chromosome":"8","Position":"19817391-19852083","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039129","HPA050570"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA039129":"AB_10794424","HPA050570":"AB_2681180"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.00e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"}},{"Gene":"INTS14","Gene synonym":["C15orf44","DKFZP564O1664","VWA9"],"Ensembl":"ENSG00000138614","Gene description":"Integrator complex subunit 14","Uniprot":["Q96SY0"],"Chromosome":"15","Position":"65578753-65611289","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040255","HPA040651"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Nuclear bodies","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Nuclear bodies","Mitochondria"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"HPA040255":"AB_10805710","HPA040651":"AB_10796559"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"}},{"Gene":"INTS2","Gene synonym":["INT2","KIAA1287"],"Ensembl":"ENSG00000108506","Gene description":"Integrator complex subunit 2","Uniprot":["Q9H0H0"],"Chromosome":"17","Position":"61865367-61928016","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"35.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049524"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049524":"AB_2680804"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.37e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"}},{"Gene":"INTS3","Gene synonym":["C1orf60","FLJ21919","INT3","SOSS-A"],"Ensembl":"ENSG00000143624","Gene description":"Integrator complex subunit 3","Uniprot":["Q68E01"],"Chromosome":"1","Position":"153728050-153774808","Protein class":["Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"2.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074391"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA074391":"AB_2686685"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.42e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"}},{"Gene":"INTS5","Gene synonym":["INT5","KIAA1698"],"Ensembl":"ENSG00000185085","Gene description":"Integrator complex subunit 5","Uniprot":["Q6P9B9"],"Chromosome":"11","Position":"62646848-62653302","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046181","HPA056915"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA046181":null,"HPA056915":"AB_2683276"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.44e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"}},{"Gene":"INTS8","Gene synonym":["C8orf52","FLJ20530","INT8","MGC131633"],"Ensembl":"ENSG00000164941","Gene description":"Integrator complex subunit 8","Uniprot":["Q75QN2"],"Chromosome":"8","Position":"94813311-94881746","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057299"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA057299":"AB_2683403"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.54e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"}},{"Gene":"INTS9","Gene synonym":["CPSF2L","FLJ10871","RC-74"],"Ensembl":"ENSG00000104299","Gene description":"Integrator complex subunit 9","Uniprot":["Q9NV88"],"Chromosome":"8","Position":"28767661-28890242","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"27.8","Excitatory neurons":"29.1","Inhibitory neurons":"30.6","Oligodendrocyte precursor cells":"30.8","Oligodendrocytes":"37.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051615","HPA066822"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA051615":"AB_2681552","HPA066822":"AB_2685729"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.45e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.71e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"}},{"Gene":"IP6K2","Gene synonym":["IHPK2"],"Ensembl":"ENSG00000068745","Gene description":"Inositol hexakisphosphate kinase 2","Uniprot":["Q9UHH9"],"Chromosome":"3","Position":"48688003-48740353","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Phospholipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007532","HPA070811"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA007532":"AB_1851542","HPA070811":"AB_2732165"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.95e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.83e-4"}},{"Gene":"IQCF1","Gene synonym":["MGC39725"],"Ensembl":"ENSG00000173389","Gene description":"IQ motif containing F1","Uniprot":["Q8N6M8"],"Chromosome":"3","Position":"51894876-51903353","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"242","RNA tissue specific nTPM":{"testis":"70.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"3378.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"30","RNA cancer specific FPKM":{"testis cancer":"1.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"IQCF2","Gene synonym":[],"Ensembl":"ENSG00000184345","Gene description":"IQ motif containing F2","Uniprot":["Q8IXL9"],"Chromosome":"3","Position":"51861615-51863424","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"89","RNA tissue specific nTPM":{"testis":"14.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"2792.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"IQCF3","Gene synonym":[],"Ensembl":"ENSG00000229972","Gene description":"IQ motif containing F3","Uniprot":["P0C7M6"],"Chromosome":"3","Position":"51826883-51830856","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"114","RNA tissue specific nTPM":{"testis":"105.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Late spermatids":"100.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"IQCF5","Gene synonym":[],"Ensembl":"ENSG00000214681","Gene description":"IQ motif containing F5","Uniprot":["A8MTL0"],"Chromosome":"3","Position":"51873721-51875601","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"487","RNA tissue specific nTPM":{"testis":"104.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"118","RNA single cell type specific nTPM":{"Early spermatids":"772.7","Late spermatids":"2775.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"IQSEC2","Gene synonym":["BRAG1","IQ-ArfGEF","KIAA0522","MRX1","MRX18","MRX78"],"Ensembl":"ENSG00000124313","Gene description":"IQ motif and Sec7 domain ArfGEF 2","Uniprot":["Q5JU85"],"Chromosome":"X","Position":"53225828-53321350","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"58.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"53.2","Late spermatids":"67.2","Proximal enterocytes":"44.3","Proximal tubular cells":"48.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"10.4","plasmacytoid DC":"10.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"dendritic cells":"10.6","monocytes":"10.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003973","HPA076533"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles","Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"HPA003973":"AB_2280343","HPA076533":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.00e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.38e-4"}},{"Gene":"IRAG1","Gene synonym":["IRAG","JAW1L","MRVI1"],"Ensembl":"ENSG00000072952","Gene description":"Inositol 1,4,5-triphosphate receptor associated 1","Uniprot":["Q9Y6F6"],"Chromosome":"11","Position":"10573091-10693988","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"169.2","Early spermatids":"44.6","Peritubular cells":"86.8","Sertoli cells":"35.9","Smooth muscle cells":"100.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"24.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"24.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"4.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Breast - Smooth muscle cells","Colon - Smooth muscle cells","Heart muscle - Smooth muscle cells","Kidney - Fibroblasts","Lung - Smooth muscle cells","Prostate - Smooth muscle cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"thalamus":"7.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008704"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA008704":"AB_1079413"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.78e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-3"}},{"Gene":"IRAG2","Gene synonym":["JAW1","LRMP"],"Ensembl":"ENSG00000118308","Gene description":"Inositol 1,4,5-triphosphate receptor associated 2","Uniprot":["Q12912"],"Chromosome":"12","Position":"25004342-25108334","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Fertilization","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"60.3","lymphoid tissue":"202.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"69.0","Microglial cells":"67.5","monocytes":"57.2","NK-cells":"80.8","Plasma cells":"52.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"210.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"Leukemia":"186.1","lymphoma":"341.9","Myeloma":"121.8"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002967","HPA007356","HPA018505"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6700","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA002967":"AB_1079161","HPA007356":null,"HPA018505":"AB_1851988"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"}},{"Gene":"IRAK1","Gene synonym":["IRAK","pelle"],"Ensembl":"ENSG00000184216","Gene description":"Interleukin 1 receptor associated kinase 1","Uniprot":["P51617"],"Chromosome":"X","Position":"154010506-154019902","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"94.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004461","HPA054476"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004461":"AB_2249106","HPA054476":"AB_2682501"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.06e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"}},{"Gene":"IRF2","Gene synonym":[],"Ensembl":"ENSG00000168310","Gene description":"Interferon regulatory factor 2","Uniprot":["P14316"],"Chromosome":"4","Position":"184387729-184474550","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030813","CAB032306","HPA057327"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cell Junctions","Cytosol"],"Antibody RRID":{"CAB032306":"AB_2249157","HPA030813":"AB_10600718","HPA057327":"AB_2683410"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.95e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.34e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"}},{"Gene":"IRS4","Gene synonym":["IRS-4","PY160"],"Ensembl":"ENSG00000133124","Gene description":"Insulin receptor substrate 4","Uniprot":["O14654"],"Chromosome":"X","Position":"108719946-108736563","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transducer"],"Disease involvement":["Cancer-related genes","Congenital hypothyroidism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.7","choroid plexus":"8.0","pituitary gland":"5.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Melanocytes":"13.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"0.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hypothalamus":"14.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"28","RNA cell line specific nTPM":{"Rhabdoid":"50.2"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"11.7","hypothalamus":"45.0"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"basal ganglia":"14.5","hypothalamus":"36.7"},"Antibody":["HPA017372"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017372":"AB_2669600"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"}},{"Gene":"IRX4","Gene synonym":[],"Ensembl":"ENSG00000113430","Gene description":"Iroquois homeobox 4","Uniprot":["P78413"],"Chromosome":"5","Position":"1877413-1887236","Protein class":["Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"15.8","heart muscle":"14.3","skin 1":"22.5","vagina":"12.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"38.5","Basal squamous epithelial cells":"48.6","Breast myoepithelial cells":"18.9","Salivary duct cells":"20.9","Squamous epithelial cells":"19.2","Suprabasal keratinocytes":"14.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"cervical cancer":"5.4","head and neck cancer":"7.3","lung cancer":"1.8","prostate cancer":"6.9","testis cancer":"7.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Esophageal cancer":"7.1","head and neck cancer":"8.8","prostate cancer":"5.7"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"12","RNA pig brain regional specific nTPM":{"medulla oblongata":"1.2","pons":"1.5"},"Antibody":["HPA064094"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA064094":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"}},{"Gene":"ISLR","Gene synonym":["HsT17563"],"Ensembl":"ENSG00000129009","Gene description":"Immunoglobulin superfamily containing leucine rich repeat","Uniprot":["O14498"],"Chromosome":"15","Position":"74173710-74176872","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"216.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Endometrial stromal cells":"194.0","Fibroblasts":"156.8","Leydig cells":"219.8","Peritubular cells":"155.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"30.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Breast - Fibroblasts","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Liver - Hepatic stellate cells","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Fibroblast_2","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"olfactory bulb":"118.0"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"spinal cord":"124.7"},"Antibody":["HPA040326","HPA050811"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA040326":"AB_2676928","HPA050811":"AB_2681243"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.89e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-3"}},{"Gene":"ISLR2","Gene synonym":["KIAA1465"],"Ensembl":"ENSG00000167178","Gene description":"Immunoglobulin superfamily containing leucine rich repeat 2","Uniprot":["Q6UXK2"],"Chromosome":"15","Position":"74100311-74138540","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"32.1","testis":"13.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"28.7","Late spermatids":"74.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"32.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Neuroblastoma":"41.1","thyroid cancer":"16.5"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012930","HPA067333"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012930":"AB_2668772","HPA067333":"AB_2685824"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"}},{"Gene":"ISOC2","Gene synonym":["FLJ23469"],"Ensembl":"ENSG00000063241","Gene description":"Isochorismatase domain containing 2","Uniprot":["Q96AB3"],"Chromosome":"19","Position":"55452985-55462343","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"284.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"299.9","Proximal tubular cells":"455.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043142"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA043142":"AB_10794653"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"}},{"Gene":"IST1","Gene synonym":["CHMP8","KIAA0174"],"Ensembl":"ENSG00000182149","Gene description":"IST1 factor associated with ESCRT-III","Uniprot":["P53990"],"Chromosome":"16","Position":"71845996-71931199","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041802","HPA054532"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041802":"AB_10794491","HPA054532":"AB_2682517"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.55e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.88e-4"}},{"Gene":"ISYNA1","Gene synonym":["Ino1","INOS","IPS"],"Ensembl":"ENSG00000105655","Gene description":"Inositol-3-phosphate synthase 1","Uniprot":["Q9NPH2"],"Chromosome":"19","Position":"18434388-18438167","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Inositol biosynthesis","Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"223.6","testis":"223.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"1134.5","Late spermatids":"217.6","Sertoli cells":"268.1","Syncytiotrophoblasts":"962.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"4.5","NK-cells":"14.4","T-cells":"8.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"244.2"},"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007931","HPA008232","CAB020720"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB020720":null,"HPA007931":"AB_2667940","HPA008232":"AB_2668018"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.23e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"}},{"Gene":"ITCH","Gene synonym":["AIP4"],"Ensembl":"ENSG00000078747","Gene description":"Itchy E3 ubiquitin protein ligase","Uniprot":["Q96J02"],"Chromosome":"20","Position":"34363241-34540748","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Apoptosis","Host-virus interaction","Immunity","Innate immunity","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"140.9","Oligodendrocytes":"245.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021126","HPA049032","CAB072824","CAB072825"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB072824":null,"CAB072825":null,"HPA021126":"AB_1851941","HPA049032":"AB_2680607"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"}},{"Gene":"ITFG1","Gene synonym":["CDA08","LNKN-1","TIP"],"Ensembl":"ENSG00000129636","Gene description":"Integrin alpha FG-GAP repeat containing 1","Uniprot":["Q8TB96"],"Chromosome":"16","Position":"47154387-47464149","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"247.0","Inhibitory neurons":"279.2","Oligodendrocytes":"248.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015590","HPA019728","HPA019752"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus","Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015590":"AB_1846347","HPA019728":"AB_1846348","HPA019752":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.95e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"}},{"Gene":"ITGA1","Gene synonym":["CD49a","VLA1"],"Ensembl":"ENSG00000213949","Gene description":"Integrin subunit alpha 1","Uniprot":["P56199"],"Chromosome":"5","Position":"52787916-52959209","Protein class":["Cancer-related genes","CD markers","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"36.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"233.4","Endothelial cells":"116.1","Hepatocytes":"86.4","Smooth muscle cells":"149.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Heart muscle - Endothelial cells","Pancreas - Endothelial cells","Prostate - Smooth muscle cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042555"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6300000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042555":"AB_10794281"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"}},{"Gene":"ITGA10","Gene synonym":[],"Ensembl":"ENSG00000143127","Gene description":"Integrin subunit alpha 10","Uniprot":["O75578"],"Chromosome":"1","Position":"145891208-145910111","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"19.8","Endothelial cells":"22.6","Late spermatids":"55.4","Microglial cells":"19.2","Skeletal myocytes":"49.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"melanoma":"6.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"19.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064008"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA064008":"AB_2685173"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.18e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"}},{"Gene":"ITGA11","Gene synonym":["HsT18964"],"Ensembl":"ENSG00000137809","Gene description":"Integrin subunit alpha 11","Uniprot":["Q9UKX5"],"Chromosome":"15","Position":"68296532-68432163","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"26.3","endometrium 1":"53.1","smooth muscle":"25.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"9.3","Cardiomyocytes":"12.6","Excitatory neurons":"13.1","Fibroblasts":"27.8","Horizontal cells":"14.7","Microglial cells":"18.2","Peritubular cells":"10.1","Smooth muscle cells":"10.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"33.8"},"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"basal ganglia":"7.3","spinal cord":"2.1"},"Antibody":["HPA051813"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051813":"AB_2681622"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.22e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"}},{"Gene":"ITGA2","Gene synonym":["CD49B"],"Ensembl":"ENSG00000164171","Gene description":"Integrin subunit alpha 2","Uniprot":["P17301"],"Chromosome":"5","Position":"52989340-53094779","Protein class":["Cancer-related genes","CD markers","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Integrin","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"145.9","Basal respiratory cells":"134.7","Ductal cells":"137.1","Exocrine glandular cells":"229.9","Oligodendrocytes":"350.1","Salivary duct cells":"212.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017690","HPA060991","HPA063556"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"43000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB017690":"AB_1124939","HPA060991":"AB_2684405","HPA063556":"AB_2685040"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"}},{"Gene":"ITGA2B","Gene synonym":["CD41","CD41B","GP2B","PPP1R93"],"Ensembl":"ENSG00000005961","Gene description":"Integrin subunit alpha 2b","Uniprot":["P08514"],"Chromosome":"17","Position":"44372180-44389649","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"16.6","epididymis":"10.7","lymphoid tissue":"11.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"39.2","Late spermatids":"27.1","Oligodendrocyte precursor cells":"9.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"basophil":"64.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"75","RNA blood lineage specific nTPM":{"granulocytes":"64.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"53","RNA cell line specific nTPM":{"Leukemia":"81.6"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018611","HPA031168","HPA031169","HPA031170","HPA031171"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"90000000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB018611":"AB_2265153","HPA031168":"AB_10664706","HPA031169":"AB_10669671","HPA031170":"AB_10696214","HPA031171":"AB_10669773"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"}},{"Gene":"ITGA3","Gene synonym":["CD49c","GAP-B3","MSK18","VCA-2","VLA3a"],"Ensembl":"ENSG00000005884","Gene description":"Integrin subunit alpha 3","Uniprot":["P26006"],"Chromosome":"17","Position":"50055968-50090481","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Epidermolysis bullosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"282.9","Ductal cells":"117.7","Exocrine glandular cells":"114.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008572","CAB018594"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB018594":"AB_668044","HPA008572":"AB_2668094"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.75e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.95e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"}},{"Gene":"ITGA4","Gene synonym":["CD49D"],"Ensembl":"ENSG00000115232","Gene description":"Integrin subunit alpha 4","Uniprot":["P13612"],"Chromosome":"2","Position":"181457202-181538940","Protein class":["Cancer-related genes","CD markers","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"47.1","lymphoid tissue":"74.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"98.7","Erythroid cells":"160.8","Kupffer cells":"123.6","Macrophages":"101.9","monocytes":"215.7","NK-cells":"274.1","Plasma cells":"115.9","T-cells":"154.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"110.4","Myeloma":"78.8"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Breast - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"cerebellum":"12.9"},"Antibody":["HPA074961"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA074961":"AB_2732273"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.29e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.08e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"}},{"Gene":"ITGA5","Gene synonym":["CD49e","FNRA"],"Ensembl":"ENSG00000161638","Gene description":"Integrin subunit alpha 5","Uniprot":["P08648"],"Chromosome":"12","Position":"54395261-54419266","Protein class":["Cancer-related genes","CD markers","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Integrin","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"398.8","smooth muscle":"361.9","urinary bladder":"386.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"447.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"89.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Smooth muscle cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"10.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002642","CAB009008"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"26000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009008":"AB_647474","HPA002642":"AB_1078469"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.07e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.43e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.91e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.23e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.44e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.89e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"}},{"Gene":"ITGA6","Gene synonym":["CD49f"],"Ensembl":"ENSG00000091409","Gene description":"Integrin subunit alpha 6","Uniprot":["P23229"],"Chromosome":"2","Position":"172427354-172506459","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["Cancer-related genes","Epidermolysis bullosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"328.8","Basal keratinocytes":"230.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"144.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"22.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"28","RNA blood lineage specific nTPM":{"granulocytes":"22.9","NK-cells":"7.1","T-cells":"12.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009009","HPA012696","HPA027582"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009009":"AB_2128038","HPA012696":"AB_1851822","HPA027582":"AB_10602606"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.35e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"}},{"Gene":"ITGA7","Gene synonym":[],"Ensembl":"ENSG00000135424","Gene description":"Integrin subunit alpha 7","Uniprot":["Q13683"],"Chromosome":"12","Position":"55684568-55716043","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Cell shape"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["Congenital muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"262.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"84.8","Cardiomyocytes":"173.2","Sertoli cells":"55.3","Skeletal myocytes":"72.3","Smooth muscle cells":"93.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"35.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"28.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Pancreas - Endothelial cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008427"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles","Vesicles"],"Antibody RRID":{"HPA008427":"AB_1851823"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.75e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.59e-5"}},{"Gene":"ITGA8","Gene synonym":[],"Ensembl":"ENSG00000077943","Gene description":"Integrin subunit alpha 8","Uniprot":["P53708"],"Chromosome":"10","Position":"15513954-15719922","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Integrin","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"37.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"81.2","Inhibitory neurons":"54.7","Microglial cells":"33.7","Oligodendrocyte precursor cells":"62.1","Smooth muscle cells":"104.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"6.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"5.7","Myeloma":"14.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Heart muscle - Smooth muscle cells","Prostate - Smooth muscle cells","Skeletal muscle - Smooth muscle cells","Skin - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"14.1"},"Antibody":["HPA003432"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA003432":"AB_1851825"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"}},{"Gene":"ITGA9","Gene synonym":["ALPHA-RLC","ITGA4L","RLC"],"Ensembl":"ENSG00000144668","Gene description":"Integrin subunit alpha 9","Uniprot":["Q13797"],"Chromosome":"3","Position":"37452115-37823507","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"80.8","Inhibitory neurons":"59.5","Leydig cells":"42.7","Microglial cells":"52.0","Oligodendrocyte precursor cells":"89.5","Peritubular cells":"71.4","Skeletal myocytes":"46.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"23.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"9.9","testis cancer":"16.9"},"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030609"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"500000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Antibody RRID":{"HPA030609":"AB_10600815"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"}},{"Gene":"ITGAD","Gene synonym":["ADB2","CD11d"],"Ensembl":"ENSG00000156886","Gene description":"Integrin subunit alpha D","Uniprot":["Q13349"],"Chromosome":"16","Position":"31393335-31426505","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lymphoid tissue":"20.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Macrophages":"1.8","NK-cells":"1.3","T-cells":"2.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"1.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026786"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026786":"AB_10603773"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"}},{"Gene":"ITGAE","Gene synonym":["CD103","HUMINAE"],"Ensembl":"ENSG00000083457","Gene description":"Integrin subunit alpha E","Uniprot":["P38570"],"Chromosome":"17","Position":"3714628-3801188","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"6.5","intestine":"5.9","lung":"6.6"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory CD8 T-cell":"3.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"3.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"Leukemia":"1.7","lymphoma":"3.2"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036313","HPA052147"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036313":"AB_10795355","HPA052147":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.78e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.56e-4"}},{"Gene":"ITGAL","Gene synonym":["CD11A","LFA-1"],"Ensembl":"ENSG00000005844","Gene description":"Integrin subunit alpha L","Uniprot":["P20701"],"Chromosome":"16","Position":"30472658-30523567","Protein class":["CD markers","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Host-virus interaction","Phagocytosis"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"36.8","lymphoid tissue":"64.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"43.6","monocytes":"151.0","NK-cells":"195.1","T-cells":"88.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"121.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"125","RNA cell line specific nTPM":{"Leukemia":"74.5","lymphoma":"40.6","Myeloma":"51.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - T-cells","Pancreas - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025011"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025011":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.63e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.34e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.57e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.69e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"}},{"Gene":"ITGAM","Gene synonym":["CD11B","CR3A","MAC-1"],"Ensembl":"ENSG00000169896","Gene description":"Integrin subunit alpha M","Uniprot":["P11215"],"Chromosome":"16","Position":"31259967-31332892","Protein class":["Cancer-related genes","CD markers","Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Immunity","Innate immunity"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["Cancer-related genes","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"bone marrow":"182.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"42.7","Hofbauer cells":"63.5","Kupffer cells":"175.2","Langerhans cells":"60.9","Macrophages":"90.3","Microglial cells":"40.1","NK-cells":"69.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Leukemia":"11.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Lung - Neutrophil_2","Skeletal muscle - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002274","CAB025091","CAB072870"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1000000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025091":null,"CAB072870":"AB_2665722","HPA002274":"AB_1078435"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.43e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.93e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.93e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"}},{"Gene":"ITGAV","Gene synonym":["CD51","MSK8","VNRA","VTNR"],"Ensembl":"ENSG00000138448","Gene description":"Integrin subunit alpha V","Uniprot":["P06756"],"Chromosome":"2","Position":"186590056-186680901","Protein class":["Cancer-related genes","CD markers","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Integrin","Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"6.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"6.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"297.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002499","HPA004856"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Focal adhesion sites","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Focal adhesion sites","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002499":"AB_563594","HPA004856":"AB_1846316"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.08e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.07e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-6"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"}},{"Gene":"ITGAX","Gene synonym":["CD11C"],"Ensembl":"ENSG00000140678","Gene description":"Integrin subunit alpha X","Uniprot":["P20702"],"Chromosome":"16","Position":"31355134-31382999","Protein class":["CD markers","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"48.1","brain":"33.7","lung":"58.1","lymphoid tissue":"67.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"57.7","Hofbauer cells":"71.9","Langerhans cells":"143.3","Macrophages":"114.2","Microglial cells":"54.7","monocytes":"272.2","NK-cells":"64.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"87.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"7.4","lymphoma":"9.2"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Kidney - T-cells","Liver - Neutrophils","Skeletal muscle - Neutrophils","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004458","HPA004723","CAB072871","CAB080214"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB004458":"AB_626859","CAB072871":"AB_2665723","CAB080214":null,"HPA004723":"AB_1846231"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.37e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"}},{"Gene":"ITGB1","Gene synonym":["CD29","FNRB","GPIIA","MDF2","MSK12"],"Ensembl":"ENSG00000150093","Gene description":"Integrin subunit beta 1","Uniprot":["P05556"],"Chromosome":"10","Position":"32887273-33005792","Protein class":["Cancer-related genes","CD markers","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Host-virus interaction","Myogenesis"],"Molecular function":["Host cell receptor for virus entry","Integrin","Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"1134.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003434","HPA059297","HPA069003"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Plasma membrane","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Plasma membrane","Focal adhesion sites"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"CAB003434":"AB_303570","HPA059297":"AB_2732634","HPA069003":"AB_2732125"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.36e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"}},{"Gene":"ITGB2","Gene synonym":["CD18","LFA-1","MAC-1","MFI7"],"Ensembl":"ENSG00000160255","Gene description":"Integrin subunit beta 2","Uniprot":["P05107"],"Chromosome":"21","Position":"44885953-44931989","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Phagocytosis"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"376.2","lymphoid tissue":"175.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"760.4","Kupffer cells":"784.3","Langerhans cells":"320.5","Macrophages":"522.0","monocytes":"733.4","NK-cells":"698.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bone cancer":"67.2","Leukemia":"198.4","lymphoma":"74.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008877","HPA016894"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Rods & Rings"],"Antibody RRID":{"HPA008877":"AB_1846256","HPA016894":"AB_1846257"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"}},{"Gene":"ITGB3","Gene synonym":["CD61","GP3A","GPIIIa"],"Ensembl":"ENSG00000259207","Gene description":"Integrin subunit beta 3","Uniprot":["P05106"],"Chromosome":"17","Position":"47253827-47313743","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Integrin","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"51.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"20.5","Proximal tubular cells":"19.6","Salivary duct cells":"15.0","Sertoli cells":"13.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"melanoma":"7.5","renal cancer":"3.6","thyroid cancer":"11.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"basophil":"5.4","neutrophil":"2.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"granulocytes":"5.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"85.8","skin cancer":"118.1"},"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Prostate - Smooth muscle cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027852"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA027852":"AB_10601760"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"}},{"Gene":"ITGB4","Gene synonym":["CD104"],"Ensembl":"ENSG00000132470","Gene description":"Integrin subunit beta 4","Uniprot":["P16144"],"Chromosome":"17","Position":"75721328-75757818","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Epidermolysis bullosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"200.6","skin 1":"205.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"163.7","Gastric mucus-secreting cells":"166.3","Mucus glandular cells":"165.9","Salivary duct cells":"292.0","Schwann cells":"167.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"4.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate basal glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"37.4"},"Antibody":["CAB002422","CAB005258","HPA036348","HPA036349"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"980000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB002422":"AB_563480","CAB005258":"AB_2129021","HPA036348":"AB_2675077","HPA036349":"AB_2675078"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.18e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.39e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"}},{"Gene":"ITGB5","Gene synonym":[],"Ensembl":"ENSG00000082781","Gene description":"Integrin subunit beta 5","Uniprot":["P18084"],"Chromosome":"3","Position":"124761948-124901418","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Integrin","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"129.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001820","CAB022050"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"64000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB022050":null,"HPA001820":"AB_1079142"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.40e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"}},{"Gene":"ITGB6","Gene synonym":[],"Ensembl":"ENSG00000115221","Gene description":"Integrin subunit beta 6","Uniprot":["P18564"],"Chromosome":"2","Position":"160099667-160200313","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Integrin","Receptor"],"Disease involvement":["Amelogenesis imperfecta","Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"68.3","skeletal muscle":"80.0","tongue":"64.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"83.8","Alveolar cells type 2":"101.5","Basal respiratory cells":"120.6","Collecting duct cells":"72.9","Ductal cells":"64.0","Exocrine glandular cells":"185.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 2","Pancreas - Ductal cells","Prostate - Urothelial cells","Skeletal muscle - Skeletal myocytes","Stomach - Gastric mucous cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023626","CAB073536"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm","Cell Junctions"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"CAB073536":null,"HPA023626":"AB_2671267"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.03e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"}},{"Gene":"ITGB7","Gene synonym":[],"Ensembl":"ENSG00000139626","Gene description":"Integrin subunit beta 7","Uniprot":["P26010"],"Chromosome":"12","Position":"53191323-53207282","Protein class":["Cancer-related genes","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Host cell receptor for virus entry","Integrin","Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"30.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"38.2","NK-cells":"96.8","Plasma cells":"104.7","Schwann cells":"33.3","T-cells":"57.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"Myeloma":"981.4"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Lung - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042277"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042277":"AB_10793877"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-4"}},{"Gene":"ITGB8","Gene synonym":[],"Ensembl":"ENSG00000105855","Gene description":"Integrin subunit beta 8","Uniprot":["P26012"],"Chromosome":"7","Position":"20330702-20415754","Protein class":["Cancer-related genes","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"53.9","choroid plexus":"39.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"366.3","Glandular and luminal cells":"453.9","Mucus glandular cells":"217.6","Oligodendrocyte precursor cells":"183.9","Salivary duct cells":"184.5","Schwann cells":"419.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"133","RNA blood cell specific nTPM":{"basophil":"16.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"133","RNA blood lineage specific nTPM":{"granulocytes":"16.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Liver - Cholangiocyte"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027796","HPA027797"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027796":"AB_10600299","HPA027797":"AB_10600879"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.77e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-3"}},{"Gene":"ITM2A","Gene synonym":["BRICD2A","E25A"],"Ensembl":"ENSG00000078596","Gene description":"Integral membrane protein 2A","Uniprot":["O43736"],"Chromosome":"X","Position":"79360384-79367667","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"322.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"387.1","Endothelial cells":"297.8","Fibroblasts":"267.8","granulocytes":"278.6","Leydig cells":"348.5","Muller glia cells":"221.4","T-cells":"220.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"51.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"172.6","eosinophil":"88.5","gdT-cell":"107.1","MAIT T-cell":"79.3","memory CD4 T-cell":"204.7","memory CD8 T-cell":"170.5","naive CD4 T-cell":"216.7","naive CD8 T-cell":"101.6","NK-cell":"130.3","T-reg":"168.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"172.6","NK-cells":"130.3","T-cells":"216.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Bone cancer":"209.5","Leukemia":"158.4","Myeloma":"56.5","prostate cancer":"117.2"},"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000296"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus","Plasma membrane"],"Antibody RRID":{"HPA000296":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.66e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-1"}},{"Gene":"ITM2B","Gene synonym":["BRI","BRI2","BRICD2B","E25B","E3-16"],"Ensembl":"ENSG00000136156","Gene description":"Integral membrane protein 2B","Uniprot":["Q9Y287"],"Chromosome":"13","Position":"48232612-48270357","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Amyloidosis","Deafness","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"4375.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"4375.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029292","HPA071992"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5800000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029292":"AB_10601917","HPA071992":"AB_2686480"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.73e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"}},{"Gene":"ITM2C","Gene synonym":["BRI3","BRICD2C","E25","hRPC.1050_D_4","ITM3"],"Ensembl":"ENSG00000135916","Gene description":"Integral membrane protein 2C","Uniprot":["Q9NQX7"],"Chromosome":"2","Position":"230864639-230879248","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1106.2","intestine":"707.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"1074.3","Distal enterocytes":"2207.4","Intestinal goblet cells":"917.1","Paneth cells":"2129.0","Plasma cells":"882.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"496.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"plasmacytoid DC":"2464.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"2464.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Skin - Fibroblast_1","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.81e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"}},{"Gene":"ITPR1","Gene synonym":["ACV","Insp3r1","IP3R1","PPP1R94","SCA15","SCA16","SCA29"],"Ensembl":"ENSG00000150995","Gene description":"Inositol 1,4,5-trisphosphate receptor type 1","Uniprot":["Q14643"],"Chromosome":"3","Position":"4493345-4847840","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","Intellectual disability","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"286.2","Inhibitory neurons":"179.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"49.9"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"13.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Prostate - Smooth muscle cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"697.2"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"208.8"},"Antibody":["HPA014765","HPA016487"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA014765":"AB_1851843","HPA016487":"AB_1851842"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.43e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"}},{"Gene":"ITPR2","Gene synonym":["CFAP48","IP3R2"],"Ensembl":"ENSG00000123104","Gene description":"Inositol 1,4,5-trisphosphate receptor type 2","Uniprot":["Q14571"],"Chromosome":"12","Position":"26335352-26833194","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"44.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"534.3","Excitatory neurons":"283.5","Microglial cells":"781.7","Oligodendrocyte precursor cells":"423.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"32.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059144","HPA062260"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA059144":"AB_2683925","HPA062260":"AB_2684728"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"}},{"Gene":"ITPR3","Gene synonym":["IP3R3"],"Ensembl":"ENSG00000096433","Gene description":"Inositol 1,4,5-trisphosphate receptor type 3","Uniprot":["Q14573"],"Chromosome":"6","Position":"33620365-33696574","Protein class":["Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"78.0","Gastric mucus-secreting cells":"116.3","Late spermatids":"235.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Stomach - Gastric mucous cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003915","HPA064704"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA003915":"AB_1851845","HPA064704":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"}},{"Gene":"ITPRID2","Gene synonym":["CS-1","KIAA1927","KRAP","SPAG13","SSFA2"],"Ensembl":"ENSG00000138434","Gene description":"ITPR interacting domain containing 2","Uniprot":["P28290"],"Chromosome":"2","Position":"181891730-181930738","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"175.8"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"2.7","granulocytes":"6.1","monocytes":"5.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034665","HPA039989"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA034665":"AB_2674271","HPA039989":"AB_2676788"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.19e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.79e-5"}},{"Gene":"ITPRIP","Gene synonym":["bA127L20.2","DANGER","KIAA1754"],"Ensembl":"ENSG00000148841","Gene description":"Inositol 1,4,5-trisphosphate receptor interacting protein","Uniprot":["Q8IWB1"],"Chromosome":"10","Position":"104309698-104338465","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"203.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"96.4","Basal squamous epithelial cells":"81.8","Squamous epithelial cells":"146.9","Suprabasal keratinocytes":"94.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"30.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043626"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA043626":"AB_10963078"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"}},{"Gene":"ITPRIPL1","Gene synonym":["KIAA1754L"],"Ensembl":"ENSG00000198885","Gene description":"ITPRIP like 1","Uniprot":["Q6GPH6"],"Chromosome":"2","Position":"96325317-96330517","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"27.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"152.7","Late spermatids":"168.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"12.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"12.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"25.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Colon - Endothelial cells","Liver - T-cells","Prostate - Prostate basal glandular cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"}},{"Gene":"ITPRIPL2","Gene synonym":["FLJ22994","LOC162073","MGC126798","MGC126800"],"Ensembl":"ENSG00000205730","Gene description":"ITPRIP like 2","Uniprot":["Q3MIP1"],"Chromosome":"16","Position":"19113932-19121629","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"111.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042011"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA042011":"AB_2677795"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"}},{"Gene":"ITSN1","Gene synonym":["ITSN","MGC134948","MGC134949","SH3D1A","SH3P17"],"Ensembl":"ENSG00000205726","Gene description":"Intersectin 1","Uniprot":["Q15811"],"Chromosome":"21","Position":"33642400-33899861","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis","Exocytosis","Host-virus interaction","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"210.7","Inhibitory neurons":"148.6","Rod photoreceptor cells":"137.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"5.5","non-classical monocyte":"5.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018007"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA018007":"AB_1851836"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"}},{"Gene":"IVD","Gene synonym":["ACAD2"],"Ensembl":"ENSG00000128928","Gene description":"Isovaleryl-CoA dehydrogenase","Uniprot":["P26440"],"Chromosome":"15","Position":"40405485-40435947","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"132.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041391","HPA044250"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA041391":"AB_2677449","HPA044250":"AB_2678875"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.95e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.91e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"}},{"Gene":"IYD","Gene synonym":["C6orf71","DEHAL1","dJ422F24.1"],"Ensembl":"ENSG00000009765","Gene description":"Iodotyrosine deiodinase","Uniprot":["Q6PHW0"],"Chromosome":"6","Position":"150368892-150405969","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Congenital hypothyroidism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"thyroid gland":"472.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"13.5","Distal enterocytes":"18.1","Hepatocytes":"24.6","Intestinal goblet cells":"27.2","Paneth cells":"17.4","Proximal enterocytes":"77.3","Proximal tubular cells":"29.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"20","RNA cancer specific FPKM":{"thyroid cancer":"80.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"2.8","Gastric cancer":"2.4"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Skin - Sebaceous gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"13","RNA mouse brain regional specific nTPM":{"hippocampal formation":"7.4","thalamus":"2.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059627"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA059627":"AB_2684086"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.22e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"}},{"Gene":"IZUMO1","Gene synonym":["IZUMO","MGC34799","OBF"],"Ensembl":"ENSG00000182264","Gene description":"Izumo sperm-egg fusion 1","Uniprot":["Q8IYV9"],"Chromosome":"19","Position":"48740852-48746909","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Fertilization"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"testis":"18.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"34","RNA single cell type specific nTPM":{"Early spermatids":"135.2","Late spermatids":"128.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038104"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038104":"AB_10670655"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"}},{"Gene":"IZUMO2","Gene synonym":["C19orf41","MGC33947","SCRL"],"Ensembl":"ENSG00000161652","Gene description":"IZUMO family member 2","Uniprot":["Q6UXV1"],"Chromosome":"19","Position":"50152548-50163195","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"283","RNA tissue specific nTPM":{"testis":"64.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"92","RNA single cell type specific nTPM":{"Early spermatids":"664.4","Late spermatids":"433.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042143"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042143":"AB_10794078"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"IZUMO3","Gene synonym":["bA20A20.1","C9orf134"],"Ensembl":"ENSG00000205442","Gene description":"IZUMO family member 3","Uniprot":["Q5VZ72"],"Chromosome":"9","Position":"24542952-24545946","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"testis":"13.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"45","RNA single cell type specific nTPM":{"Early spermatids":"277.8","Late spermatids":"117.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"Sarcoma":"5.8"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"JAG1","Gene synonym":["AGS","AHD","AWS","CD339","HJ1","JAGL1"],"Ensembl":"ENSG00000101384","Gene description":"Jagged canonical Notch ligand 1","Uniprot":["P78504"],"Chromosome":"20","Position":"10637684-10673999","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Notch signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Charcot-Marie-Tooth disease","Deafness","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"263.6","Endometrial ciliated cells":"189.9","Smooth muscle cells":"165.8","Squamous epithelial cells":"339.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010343","HPA021555"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"25000000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010343":"AB_649685","HPA021555":"AB_1851969"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.10e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"}},{"Gene":"JAG2","Gene synonym":[],"Ensembl":"ENSG00000184916","Gene description":"Jagged canonical Notch ligand 2","Uniprot":["Q9Y219"],"Chromosome":"14","Position":"105140982-105168824","Protein class":["Predicted membrane proteins"],"Biological process":["Notch signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"51.0","Basal respiratory cells":"30.0","Breast myoepithelial cells":"30.6","Endothelial cells":"34.2","Salivary duct cells":"37.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Colon - Endothelial cells","Prostate - Prostate basal glandular cells","Stomach - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025481","HPA030636","HPA050567"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB025481":null,"HPA030636":"AB_10602607","HPA050567":"AB_2681178"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"}},{"Gene":"JAGN1","Gene synonym":["FLJ14602","GL009"],"Ensembl":"ENSG00000171135","Gene description":"Jagunal homolog 1","Uniprot":["Q8N5M9"],"Chromosome":"3","Position":"9890574-9894349","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067610"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA067610":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"}},{"Gene":"JAKMIP1","Gene synonym":["FLJ31564","Gababrbp","JAMIP1","MARLIN1"],"Ensembl":"ENSG00000152969","Gene description":"Janus kinase and microtubule interacting protein 1","Uniprot":["Q96N16"],"Chromosome":"4","Position":"6026199-6200591","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"31.1","pituitary gland":"10.2","retina":"17.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"34.5","Excitatory neurons":"81.7","Inhibitory neurons":"52.3","Muller glia cells":"42.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"17","RNA blood cell specific nTPM":{"gdT-cell":"25.3","MAIT T-cell":"11.2","memory CD4 T-cell":"11.2","memory CD8 T-cell":"22.6","naive CD8 T-cell":"10.1","T-reg":"36.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"T-cells":"36.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"12.6","Myeloma":"9.6","Neuroblastoma":"8.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Colon - Colon enteroendocrine cells","Liver - T-cells","Pancreas - Beta cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044570"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044570":"AB_2678995"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"}},{"Gene":"JAKMIP3","Gene synonym":["bA140A10.5","C10orf14","C10orf39","FLJ37857","KIAA4091","NECC2"],"Ensembl":"ENSG00000188385","Gene description":"Janus kinase and microtubule interacting protein 3","Uniprot":["Q5VZ66"],"Chromosome":"10","Position":"132036336-132184858","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"20.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"13.9","Excitatory neurons":"38.8","Inhibitory neurons":"31.6","Oligodendrocyte precursor cells":"26.0","Oligodendrocytes":"87.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022872"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA022872":"AB_2249331"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"}},{"Gene":"JAM2","Gene synonym":["C21orf43","CD322","JAM-B","JAMB","VE-JAM"],"Ensembl":"ENSG00000154721","Gene description":"Junctional adhesion molecule 2","Uniprot":["P57087"],"Chromosome":"21","Position":"25639258-25717562","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"63.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"187.0","Astrocytes":"79.1","Endothelial cells":"126.8","Microglial cells":"80.3","Oligodendrocyte precursor cells":"73.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"27.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"9.0","Rhabdoid":"8.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Colon - Enteric glia cells","Liver - Vascular Endothelial cells","Skin - Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028789","HPA077346"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"360000","Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA028789":"AB_2732443","HPA077346":"AB_2732341"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"}},{"Gene":"JAM3","Gene synonym":["JAM-C","JAMC"],"Ensembl":"ENSG00000166086","Gene description":"Junctional adhesion molecule 3","Uniprot":["Q9BX67"],"Chromosome":"11","Position":"134069071-134152001","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Angiogenesis","Cell adhesion","Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"83.1","Extravillous trophoblasts":"78.0","Oligodendrocyte precursor cells":"73.2","Oligodendrocytes":"323.6","Rod photoreceptor cells":"70.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"5.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"5.3","T-cells":"2.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003417","HPA050434"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA003417":"AB_1851981","HPA050434":"AB_2681126"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.68e-4"}},{"Gene":"JAML","Gene synonym":["AMICA","AMICA1","Gm638"],"Ensembl":"ENSG00000160593","Gene description":"Junction adhesion molecule like","Uniprot":["Q86YT9"],"Chromosome":"11","Position":"118193725-118225094","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"43.3","lymphoid tissue":"68.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"dendritic cells":"275.0","Hofbauer cells":"105.6","Kupffer cells":"135.5","Langerhans cells":"331.4","Macrophages":"148.9","monocytes":"205.6","T-cells":"85.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"3529.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"1017.6","granulocytes":"3529.6","monocytes":"1023.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Leukemia":"6.4","lymphoma":"15.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Breast - T-cells","Colon - T-cells","Kidney - T-cells","Prostate - T-cells","Stomach - T-cells","Testis - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"11","RNA pig brain regional specific nTPM":{"cerebellum":"58.0"},"Antibody":["HPA005854","HPA047919"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA005854":null,"HPA047919":"AB_2680209"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.11e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.92e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"}},{"Gene":"JKAMP","Gene synonym":["C14orf100","CDA06","HSPC213","HSPC327","JAMP"],"Ensembl":"ENSG00000050130","Gene description":"JNK1\/MAPK8 associated membrane protein","Uniprot":["Q9P055"],"Chromosome":"14","Position":"59484443-59505410","Protein class":["Cancer-related genes","Predicted membrane proteins"],"Biological process":["Unfolded protein response"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"204.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031172","HPA071650"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA031172":"AB_10670563","HPA071650":"AB_2686429"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.09e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"}},{"Gene":"JPH1","Gene synonym":["JP-1"],"Ensembl":"ENSG00000104369","Gene description":"Junctophilin 1","Uniprot":["Q9HDC5"],"Chromosome":"8","Position":"74234700-74321540","Protein class":["Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"skeletal muscle":"237.4","tongue":"106.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"33.5","Excitatory neurons":"81.0","Inhibitory neurons":"49.2","Skeletal myocytes":"153.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"20.9"},"RNA tissue cell type enrichment":["Kidney - Podocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008996","HPA009413","CAB013461"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB013461":null,"HPA008996":"AB_1852023","HPA009413":"AB_1079163"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.77e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"}},{"Gene":"JPH2","Gene synonym":["JP-2"],"Ensembl":"ENSG00000149596","Gene description":"Junctophilin 2","Uniprot":["Q9BR39"],"Chromosome":"20","Position":"44106590-44187188","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"85.2","skeletal muscle":"120.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"70.4","Skeletal myocytes":"67.3","Smooth muscle cells":"23.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Colon - Smooth muscle cells","Heart muscle - Cardiomyocytes","Lung - Smooth muscle cells","Prostate - Smooth muscle cells","Skeletal muscle - Skeletal myocytes","Skin - Smooth muscle cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052646"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052646":"AB_2681899"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"}},{"Gene":"JPH3","Gene synonym":["CAGL237","HDL2","JP-3","JP3","TNRC22"],"Ensembl":"ENSG00000154118","Gene description":"Junctophilin 3","Uniprot":["Q8WXH2"],"Chromosome":"16","Position":"87601835-87698156","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"59.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Bipolar cells":"26.6","Cone photoreceptor cells":"15.5","Early spermatids":"29.8","Excitatory neurons":"32.8","Horizontal cells":"26.3","Inhibitory neurons":"28.0","Late spermatids":"26.4","Oligodendrocyte precursor cells":"10.1","Rod photoreceptor cells":"11.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.7"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"amygdala":"17.1","basal ganglia":"24.6","cerebral cortex":"59.1","hippocampal formation":"42.7","white matter":"20.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"5.8","Neuroblastoma":"6.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076304"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA076304":"AB_2686793"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"}},{"Gene":"JPH4","Gene synonym":["JPHL1","KIAA1831"],"Ensembl":"ENSG00000092051","Gene description":"Junctophilin 4","Uniprot":["Q96JJ6"],"Chromosome":"14","Position":"23568035-23578790","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"126.2","pituitary gland":"66.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Bipolar cells":"143.9","Horizontal cells":"457.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"6.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"2.8","myeloid DC":"3.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"3.2","monocytes":"2.8"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"40.4"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045022"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA045022":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-3"}},{"Gene":"JPT2","Gene synonym":["C16orf34","FLJ13092","HN1L","KIAA1426","L11"],"Ensembl":"ENSG00000206053","Gene description":"Jupiter microtubule associated homolog 2","Uniprot":["Q9H910"],"Chromosome":"16","Position":"1678256-1702280","Protein class":["Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"229.8","Late spermatids":"138.9","Syncytiotrophoblasts":"191.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041888","HPA041908"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"76000","Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041888":"AB_10793937","HPA041908":"AB_10794160"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.85e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.14e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"}},{"Gene":"JTB","Gene synonym":["hJT","PAR"],"Ensembl":"ENSG00000143543","Gene description":"Jumping translocation breakpoint","Uniprot":["O76095"],"Chromosome":"1","Position":"153974269-153977674","Protein class":["Cancer-related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006514"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA006514":"AB_1079164"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.87e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.65e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-3"}},{"Gene":"KALRN","Gene synonym":["ARHGEF24","DUET","duo","HAPIP","Hs.8004","Kalirin","TRAD"],"Ensembl":"ENSG00000160145","Gene description":"Kalirin RhoGEF kinase","Uniprot":["O60229"],"Chromosome":"3","Position":"124080023-124726325","Protein class":["Cancer-related genes","Enzymes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"31.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"1413.9","Inhibitory neurons":"468.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"1.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011913","CAB026456"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"83000","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB026456":null,"HPA011913":"AB_1850494"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"}},{"Gene":"KANSL1L","Gene synonym":["C2orf67","FLJ23861","FLJ32349","KIAA1267L","MSL1v2"],"Ensembl":"ENSG00000144445","Gene description":"KAT8 regulatory NSL complex subunit 1 like","Uniprot":["A0AUZ9"],"Chromosome":"2","Position":"210021421-210171409","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"parathyroid gland":"198.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"110.1","Inhibitory neurons":"115.4","Microglial cells":"100.3","Oligodendrocyte precursor cells":"182.4","Oligodendrocytes":"150.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043102","HPA046790"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043102":"AB_2678316","HPA046790":"AB_2679808"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"}},{"Gene":"KANTR","Gene synonym":["LINC01155","Spasm"],"Ensembl":"ENSG00000232593","Gene description":"KDM5C adjacent transcript","Uniprot":[],"Chromosome":"X","Position":"53094145-53170914","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"3.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"37.8","Rod photoreceptor cells":"52.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-3"}},{"Gene":"KASH5","Gene synonym":["CCDC155","FLJ32658"],"Ensembl":"ENSG00000161609","Gene description":"KASH domain containing 5","Uniprot":["Q8N6L0"],"Chromosome":"19","Position":"49388219-49417990","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Meiosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"testis":"54.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"32.9","Early spermatids":"24.3","Late spermatids":"11.6","Spermatocytes":"97.4","Spermatogonia":"18.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.5"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"10","RNA brain regional specific nTPM":{"cerebellum":"4.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Bone cancer":"5.6"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019937","HPA019940"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019937":"AB_1848877","HPA019940":"AB_1848879"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"}},{"Gene":"KATNB1","Gene synonym":[],"Ensembl":"ENSG00000140854","Gene description":"Katanin regulatory subunit B1","Uniprot":["Q9BVA0"],"Chromosome":"16","Position":"57735739-57757244","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":["Disease variant","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"114.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041165","HPA041839"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Microtubules"],"Antibody RRID":{"HPA041165":"AB_10795584","HPA041839":"AB_10795598"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.24e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.93e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.44e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"}},{"Gene":"KCNA1","Gene synonym":["AEMK","HUK1","Kv1.1","MBK1","RBK1"],"Ensembl":"ENSG00000111262","Gene description":"Potassium voltage-gated channel subfamily A member 1","Uniprot":["Q09470"],"Chromosome":"12","Position":"4909905-4918256","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"50.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"8.9","Excitatory neurons":"39.0","Horizontal cells":"21.8","Inhibitory neurons":"18.3","Oligodendrocyte precursor cells":"15.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lung cancer":"2.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074471"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074471":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-4"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNA10","Gene synonym":["Kv1.8"],"Ensembl":"ENSG00000143105","Gene description":"Potassium voltage-gated channel subfamily A member 10","Uniprot":["Q16322"],"Chromosome":"1","Position":"110517217-110519175","Protein class":["FDA approved drug targets","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNA2","Gene synonym":["HK4","Kv1.2"],"Ensembl":"ENSG00000177301","Gene description":"Potassium voltage-gated channel subfamily A member 2","Uniprot":["P16389"],"Chromosome":"1","Position":"110519837-110631474","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"81.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"48.4","Early spermatids":"15.1","Excitatory neurons":"36.3","Horizontal cells":"34.0","Inhibitory neurons":"36.3","Muller glia cells":"15.9","Oligodendrocyte precursor cells":"34.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.2","testis cancer":"1.0"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"81.3"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"T-cells":"1.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"8.9","Myeloma":"3.0"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001976"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001976":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"}},{"Gene":"KCNA3","Gene synonym":["HLK3","HPCN3","Kv1.3","MK3"],"Ensembl":"ENSG00000177272","Gene description":"Potassium voltage-gated channel subfamily A member 3","Uniprot":["P22001"],"Chromosome":"1","Position":"110672465-110674940","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"25.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"12.9","Inhibitory neurons":"58.7","Plasma cells":"54.8","T-cells":"23.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"4.9","T-cells":"14.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"7.2","Myeloma":"25.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Colon - T-cells","Skin - T-cells","Testis - Spermatocytes","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016625"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016625":"AB_2669407"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"}},{"Gene":"KCNA4","Gene synonym":["HK1","HPCN2","KCNA4L","Kv1.4"],"Ensembl":"ENSG00000182255","Gene description":"Potassium voltage-gated channel subfamily A member 4","Uniprot":["P22459"],"Chromosome":"11","Position":"30009730-30017030","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Cataract","Disease variant","Dystonia","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"adrenal gland":"6.1","brain":"20.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"12.9","Cardiomyocytes":"3.5","Excitatory neurons":"8.1","Horizontal cells":"7.0","Muller glia cells":"4.0","Thymic epithelial cells":"6.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"20.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Adipocytes (Breast)","Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001977","HPA016422"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001977":null,"HPA016422":"AB_1855574"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNA5","Gene synonym":["HK2","HPCN1","Kv1.5"],"Ensembl":"ENSG00000130037","Gene description":"Potassium voltage-gated channel subfamily A member 5","Uniprot":["P22460"],"Chromosome":"12","Position":"5043879-5046788","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Atrial fibrillation","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"choroid plexus":"52.7","heart muscle":"39.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"130.0","Cardiomyocytes":"21.7","dendritic cells":"19.1","Horizontal cells":"34.6","Smooth muscle cells":"22.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"2.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"122","RNA blood cell specific nTPM":{"plasmacytoid DC":"12.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"122","RNA blood lineage specific nTPM":{"dendritic cells":"12.2"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"1.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021516","CAB022562"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022562":null,"HPA021516":"AB_2670732"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"}},{"Gene":"KCNA6","Gene synonym":["HBK2","Kv1.6","PPP1R96"],"Ensembl":"ENSG00000151079","Gene description":"Potassium voltage-gated channel subfamily A member 6","Uniprot":["P17658"],"Chromosome":"12","Position":"4809176-4813412","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"8.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Astrocytes":"13.6","Excitatory neurons":"27.4","Inhibitory neurons":"52.0","Oligodendrocyte precursor cells":"21.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"8.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076475"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA076475":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNA7","Gene synonym":["HAK6","Kv1.7"],"Ensembl":"ENSG00000104848","Gene description":"Potassium voltage-gated channel subfamily A member 7","Uniprot":["Q96RP8"],"Chromosome":"19","Position":"49067418-49072941","Protein class":["FDA approved drug targets","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"51","RNA tissue specific nTPM":{"skeletal muscle":"75.7","tongue":"19.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"33","RNA single cell type specific nTPM":{"Skeletal myocytes":"58.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075990"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA075990":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"}},{"Gene":"KCNAB2","Gene synonym":["AKR6A5","HKvbeta2.1","HKvbeta2.2","KCNA2B"],"Ensembl":"ENSG00000069424","Gene description":"Potassium voltage-gated channel subfamily A regulatory beta subunit 2","Uniprot":["Q13303"],"Chromosome":"1","Position":"5990927-6101193","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Oxidoreductase","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"188.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"66.9","Hofbauer cells":"80.3","Horizontal cells":"80.8","Melanocytes":"95.8","monocytes":"203.1","NK-cells":"81.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"melanoma":"29.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"139.3","lymphoma":"102.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001975"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001975":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.50e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"}},{"Gene":"KCNB1","Gene synonym":["Kv2.1"],"Ensembl":"ENSG00000158445","Gene description":"Potassium voltage-gated channel subfamily B member 1","Uniprot":["Q14721"],"Chromosome":"20","Position":"49293394-49484297","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Exocytosis","Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"retina":"113.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"136.9","Cone photoreceptor cells":"313.6","Excitatory neurons":"148.5","Inhibitory neurons":"87.6","Rod photoreceptor cells":"358.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.3"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"17.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"3.7","Rhabdoid":"3.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001979","HPA042434"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001979":null,"HPA042434":"AB_2677996"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-4"}},{"Gene":"KCNB2","Gene synonym":["Kv2.2"],"Ensembl":"ENSG00000182674","Gene description":"Potassium voltage-gated channel subfamily B member 2","Uniprot":["Q92953"],"Chromosome":"8","Position":"72537225-72938349","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.6","lymphoid tissue":"2.3","retina":"4.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"180.9","Excitatory neurons":"275.0","Inhibitory neurons":"235.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"2.8"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065970"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Plasma membrane","Midbody"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli","Midbody"],"Antibody RRID":{"HPA065970":"AB_2685591"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNC1","Gene synonym":["Kv3.1"],"Ensembl":"ENSG00000129159","Gene description":"Potassium voltage-gated channel subfamily C member 1","Uniprot":["P48547"],"Chromosome":"11","Position":"17734774-17856804","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"47.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"56.6","Excitatory neurons":"47.5","Horizontal cells":"277.5","Inhibitory neurons":"117.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"1.1","testis cancer":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"3.2","neutrophil":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"3.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"7.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047634","HPA048249"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA047634":"AB_2680109","HPA048249":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"}},{"Gene":"KCNC2","Gene synonym":["Kv3.2"],"Ensembl":"ENSG00000166006","Gene description":"Potassium voltage-gated channel subfamily C member 2","Uniprot":["Q96PR1"],"Chromosome":"12","Position":"75040077-75209839","Protein class":["Disease related genes","FDA approved drug targets","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"46.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Excitatory neurons":"384.9","Inhibitory neurons":"1395.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"breast cancer":"1.5","prostate cancer":"4.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"1.4","Sarcoma":"1.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019664","CAB022571"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022571":null,"HPA019664":"AB_1855578"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNC3","Gene synonym":["Kv3.3","SCA13"],"Ensembl":"ENSG00000131398","Gene description":"Potassium voltage-gated channel subfamily C member 3","Uniprot":["Q14003"],"Chromosome":"19","Position":"50311937-50333515","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","FDA approved drug targets","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"75.8","thyroid gland":"52.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"19.7","Endometrial ciliated cells":"24.4","Excitatory neurons":"15.4","Glandular and luminal cells":"15.1","Inhibitory neurons":"17.9","monocytes":"12.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"75.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Stomach - Gastric enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018041"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018041":"AB_1855579"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"}},{"Gene":"KCNC4","Gene synonym":["C1orf30","HKSHIIIC","Kv3.4"],"Ensembl":"ENSG00000116396","Gene description":"Potassium voltage-gated channel subfamily C member 4","Uniprot":["Q03721"],"Chromosome":"1","Position":"110210314-110283100","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"24.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"44.0","Sertoli cells":"30.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014740"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA014740":"AB_1855580"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"}},{"Gene":"KCND1","Gene synonym":["Kv4.1"],"Ensembl":"ENSG00000102057","Gene description":"Potassium voltage-gated channel subfamily D member 1","Uniprot":["Q9NSA2"],"Chromosome":"X","Position":"48961378-48971844","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"2.4","Peritubular cells":"4.1","Rod photoreceptor cells":"4.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000524","HPA001066"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA000524":"AB_2666013","HPA001066":"AB_1079662"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.66e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"}},{"Gene":"KCND2","Gene synonym":["KIAA1044","Kv4.2","RK5"],"Ensembl":"ENSG00000184408","Gene description":"Potassium voltage-gated channel subfamily D member 2","Uniprot":["Q9NZV8"],"Chromosome":"7","Position":"120273175-120750337","Protein class":["Disease related genes","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Autism","Autism spectrum disorder","Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"47.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Excitatory neurons":"680.6","Inhibitory neurons":"1045.4","Oligodendrocyte precursor cells":"1870.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"6.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"2.7"},"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029068"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029068":"AB_10601436"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"}},{"Gene":"KCND3","Gene synonym":["KSHIVB","Kv4.3","SCA19","SCA22"],"Ensembl":"ENSG00000171385","Gene description":"Potassium voltage-gated channel subfamily D member 3","Uniprot":["Q9UK17"],"Chromosome":"1","Position":"111770662-111989668","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Brugada syndrome","Disease variant","FDA approved drug targets","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"35.1","Cardiomyocytes":"37.3","Excitatory neurons":"104.1","Hepatocytes":"33.0","Horizontal cells":"41.7","Inhibitory neurons":"86.3","Late spermatids":"34.9","Oligodendrocyte precursor cells":"43.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"8.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"1.5","lung cancer":"1.5"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029452"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029452":"AB_10602239"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-3"}},{"Gene":"KCNE1","Gene synonym":["IsK","JLNS2","LQT5","minK"],"Ensembl":"ENSG00000180509","Gene description":"Potassium voltage-gated channel subfamily E regulatory subunit 1","Uniprot":["P15382"],"Chromosome":"21","Position":"34446688-34512210","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Deafness","Disease variant","Long QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"choroid plexus":"13.3","fallopian tube":"10.0","heart muscle":"5.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"23.9","Kupffer cells":"42.5","Macrophages":"23.2","monocytes":"35.4","Respiratory ciliated cells":"37.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1.9"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"granulocytes":"1.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Rhabdoid":"3.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Prostate - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"}},{"Gene":"KCNE1B","Gene synonym":[],"Ensembl":"ENSG00000276289","Gene description":"Potassium voltage-gated channel subfamily E regulatory subunit 1B","Uniprot":["A0A087WTH5"],"Chromosome":"21","Position":"7816675-7829926","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"7.1","fallopian tube":"5.7","heart muscle":"6.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"1.1","Respiratory ciliated cells":"3.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.0","eosinophil":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"1.2","testis cancer":"1.1"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNE2","Gene synonym":["LQT6","MiRP1"],"Ensembl":"ENSG00000159197","Gene description":"Potassium voltage-gated channel subfamily E regulatory subunit 2","Uniprot":["Q9Y6J6"],"Chromosome":"21","Position":"34364006-34371381","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Atrial fibrillation","Disease variant","Long QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"44","RNA tissue specific nTPM":{"stomach 1":"316.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"137.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"stomach cancer":"2.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"pons and medulla":"29.0"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029706","HPA051553"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029706":"AB_2673159","HPA051553":"AB_2681532"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"}},{"Gene":"KCNE3","Gene synonym":["HOKPP","MiRP2"],"Ensembl":"ENSG00000175538","Gene description":"Potassium voltage-gated channel subfamily E regulatory subunit 3","Uniprot":["Q9Y6H6"],"Chromosome":"11","Position":"74454841-74467729","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Brugada syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"70.5","stomach 1":"56.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"44.1","Hofbauer cells":"49.3","Kupffer cells":"118.6","Macrophages":"46.0","monocytes":"48.3","Undifferentiated cells":"32.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"48","RNA blood cell specific nTPM":{"basophil":"51.4","classical monocyte":"38.5","eosinophil":"23.4","intermediate monocyte":"41.8","myeloid DC":"18.3","neutrophil":"53.1","non-classical monocyte":"36.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"115","RNA blood lineage specific nTPM":{"dendritic cells":"18.3","granulocytes":"53.1","monocytes":"41.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"70.6","colorectal cancer":"49.0","Gastric cancer":"52.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014849"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014849":"AB_1852112"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.28e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"}},{"Gene":"KCNE4","Gene synonym":["MiRP3"],"Ensembl":"ENSG00000152049","Gene description":"Potassium voltage-gated channel subfamily E regulatory subunit 4","Uniprot":["Q8WWG9"],"Chromosome":"2","Position":"223051814-223198399","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"smooth muscle":"37.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"26.8","Leydig cells":"20.0","Melanocytes":"67.9","Muller glia cells":"23.5","Sertoli cells":"38.7","Smooth muscle cells":"88.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"20.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"42.9"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Lung - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011420"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Microtubules"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA011420":"AB_1079170"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.42e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-3"}},{"Gene":"KCNE5","Gene synonym":["KCNE1L"],"Ensembl":"ENSG00000176076","Gene description":"Potassium voltage-gated channel subfamily E regulatory subunit 5","Uniprot":["Q9UJ90"],"Chromosome":"X","Position":"109623700-109625172","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Alport syndrome","Deafness","Elliptocytosis","Hereditary hemolytic anemia","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"9.8","skeletal muscle":"4.0","tongue":"4.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"4.4","dendritic cells":"16.8","granulocytes":"3.6","Melanocytes":"8.7","Muller glia cells":"5.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"7.9","testis cancer":"2.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"2.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"22","RNA cell line specific nTPM":{"Leukemia":"13.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-3"}},{"Gene":"KCNF1","Gene synonym":["IK8","KCNF","kH1","Kv5.1"],"Ensembl":"ENSG00000162975","Gene description":"Potassium voltage-gated channel modifier subfamily F member 1","Uniprot":["Q9H3M0"],"Chromosome":"2","Position":"10911934-10914225","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"brain":"28.9","choroid plexus":"32.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"9.2","Extravillous trophoblasts":"17.7","Inhibitory neurons":"8.5","Oligodendrocyte precursor cells":"17.3","Syncytiotrophoblasts":"7.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"27.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"9.6"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells (progenitors)","Pancreas - Beta cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014738","HPA062278"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA014738":"AB_1852114","HPA062278":"AB_2732679"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"}},{"Gene":"KCNG1","Gene synonym":["K13","KCNG","kH2","Kv6.1"],"Ensembl":"ENSG00000026559","Gene description":"Potassium voltage-gated channel modifier subfamily G member 1","Uniprot":["Q9UIX4"],"Chromosome":"20","Position":"51003656-51023107","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"46.8","endometrium 1":"87.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"51.5","Early spermatids":"18.9","Granulosa cells":"31.6","Late spermatids":"21.5","Syncytiotrophoblasts":"83.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"8.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"20","RNA blood cell specific nTPM":{"naive B-cell":"7.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"71","RNA blood lineage specific nTPM":{"B-cells":"7.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"amygdala":"20.6","basal ganglia":"19.1","cerebral cortex":"14.9","hippocampal formation":"18.1","white matter":"9.1"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"amygdala":"12.6","basal ganglia":"11.1","cerebral cortex":"22.4","hippocampal formation":"16.8"},"Antibody":["HPA039530","HPA040024"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA039530":"AB_10795144","HPA040024":"AB_10796338"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"}},{"Gene":"KCNG2","Gene synonym":["KCNF2","Kv6.2"],"Ensembl":"ENSG00000178342","Gene description":"Potassium voltage-gated channel modifier subfamily G member 2","Uniprot":["Q9UJ96"],"Chromosome":"18","Position":"79863668-79900184","Protein class":["Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"3.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"28.4","Excitatory neurons":"19.0","Extravillous trophoblasts":"9.6","Horizontal cells":"27.6","Inhibitory neurons":"30.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"hippocampal formation":"10.3"},"Antibody":["HPA048628"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048628":"AB_2680466"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"}},{"Gene":"KCNG3","Gene synonym":["Kv6.3"],"Ensembl":"ENSG00000171126","Gene description":"Potassium voltage-gated channel modifier subfamily G member 3","Uniprot":["Q8TAE7"],"Chromosome":"2","Position":"42442017-42493982","Protein class":["Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"5.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"10.3","Excitatory neurons":"16.1","Glandular and luminal cells":"11.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"1.1"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"amygdala":"1.8","basal ganglia":"2.3","cerebral cortex":"3.7","hippocampal formation":"5.7","pons":"1.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"6.8"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041625"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytoplasmic bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA041625":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"KCNG4","Gene synonym":["Kv6.4"],"Ensembl":"ENSG00000168418","Gene description":"Potassium voltage-gated channel modifier subfamily G member 4","Uniprot":["Q8TDN1"],"Chromosome":"16","Position":"84218667-84239750","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"3.4","retina":"4.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Bipolar cells":"58.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"cerebellum":"90.5","pons and medulla":"27.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063516"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA063516":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNH1","Gene synonym":["eag","eag1","h-eag","hEAG","Kv10.1"],"Ensembl":"ENSG00000143473","Gene description":"Potassium voltage-gated channel subfamily H member 1","Uniprot":["O95259"],"Chromosome":"1","Position":"210676823-211134165","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Calmodulin-binding","Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"17.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"526.8","Inhibitory neurons":"254.8","Oligodendrocytes":"110.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"4.5"},"RNA tissue cell type enrichment":["Skin - Outer root sheath cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"34.0","cerebellum":"19.1","cerebral cortex":"23.9","hippocampal formation":"17.9","olfactory bulb":"8.9"},"Antibody":["HPA014551","HPA019445","HPA076421"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA014551":"AB_2669038","HPA019445":"AB_1852118","HPA076421":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"}},{"Gene":"KCNH2","Gene synonym":["erg1","HERG","Kv11.1","LQT2"],"Ensembl":"ENSG00000055118","Gene description":"Potassium voltage-gated channel subfamily H member 2","Uniprot":["Q12809"],"Chromosome":"7","Position":"150944961-150978321","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Deafness","Disease variant","FDA approved drug targets","Long QT syndrome","Short QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"42.3","pituitary gland":"43.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"213.1","Cardiomyocytes":"81.3","Erythroid cells":"117.2","granulocytes":"39.3","Horizontal cells":"58.3","Sertoli cells":"66.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"27.5","Neuroblastoma":"40.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Lung - Fibroblast_1","Pancreas - Alpha cells","Pancreas - Beta cells","Prostate - Smooth muscle cells","Skin - Smooth muscle cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.06e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.61e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"}},{"Gene":"KCNH3","Gene synonym":["BEC1","elk2","Kv12.2"],"Ensembl":"ENSG00000135519","Gene description":"Potassium voltage-gated channel subfamily H member 3","Uniprot":["Q9ULD8"],"Chromosome":"12","Position":"49539030-49558337","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"39.4","pituitary gland":"25.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"10.7","Excitatory neurons":"57.4","Inhibitory neurons":"18.8","Late spermatids":"10.6","Respiratory ciliated cells":"11.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"9.8"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"21","RNA brain regional specific nTPM":{"amygdala":"29.6","basal ganglia":"25.6","cerebral cortex":"39.4","hippocampal formation":"30.6","white matter":"24.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"5.3"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"}},{"Gene":"KCNH4","Gene synonym":["elk1","Kv12.3"],"Ensembl":"ENSG00000089558","Gene description":"Potassium voltage-gated channel subfamily H member 4","Uniprot":["Q9UQ05"],"Chromosome":"17","Position":"42156891-42181142","Protein class":["Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"14.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"6.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"basal ganglia":"14.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"4.7","Neuroblastoma":"6.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"}},{"Gene":"KCNH5","Gene synonym":["eag2","H-EAG2","hEAG2","Kv10.2"],"Ensembl":"ENSG00000140015","Gene description":"Potassium voltage-gated channel subfamily H member 5","Uniprot":["Q8NCM2"],"Chromosome":"14","Position":"62699464-63102037","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Calmodulin-binding","Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"8.5","retina":"4.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Bipolar cells":"48.0","Excitatory neurons":"182.4","Horizontal cells":"51.9","Inhibitory neurons":"72.6","Oligodendrocyte precursor cells":"63.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"1.4","cervical cancer":"1.7"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030487","HPA072351"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Centrosome"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA030487":"AB_10609995","HPA072351":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"}},{"Gene":"KCNH6","Gene synonym":["erg2","HERG2","Kv11.2"],"Ensembl":"ENSG00000173826","Gene description":"Potassium voltage-gated channel subfamily H member 6","Uniprot":["Q9H252"],"Chromosome":"17","Position":"63523334-63548977","Protein class":["FDA approved drug targets","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"4.8","kidney":"7.0","pituitary gland":"5.3","prostate":"3.9","retina":"4.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"42.7","Cone photoreceptor cells":"12.1","Enteroendocrine cells":"27.7","Horizontal cells":"11.5","Prostatic glandular cells":"25.0","Proximal enterocytes":"41.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"5.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"6.7","lung cancer":"7.6","prostate cancer":"5.9"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Pancreas - Alpha cells","Prostate - Prostate glandular cells","Stomach - Gastric enteroendocrine cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"medulla oblongata":"1.1","olfactory bulb":"2.4","spinal cord":"2.5"},"Antibody":["HPA061704"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA061704":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"}},{"Gene":"KCNH7","Gene synonym":["erg3","HERG3","Kv11.3"],"Ensembl":"ENSG00000184611","Gene description":"Potassium voltage-gated channel subfamily H member 7","Uniprot":["Q9NS40"],"Chromosome":"2","Position":"162371407-162838767","Protein class":["FDA approved drug targets","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"5.9","retina":"1.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"676.9","Inhibitory neurons":"344.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"5.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Neutrophil_2","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebral cortex":"53.0"},"Antibody":["HPA018039"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018039":"AB_1852125"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"}},{"Gene":"KCNH8","Gene synonym":["elk3","Kv12.1"],"Ensembl":"ENSG00000183960","Gene description":"Potassium voltage-gated channel subfamily H member 8","Uniprot":["Q96L42"],"Chromosome":"3","Position":"19148510-19535642","Protein class":["Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"16.0","pituitary gland":"10.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"61","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"317.7","Oligodendrocytes":"933.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"1.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"colorectal cancer":"1.3","Gallbladder cancer":"3.9","Gastric cancer":"1.1","lung cancer":"1.2","Neuroblastoma":"2.4","prostate cancer":"1.3"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016586","HPA077537","HPA077773"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA016586":"AB_1852127","HPA077537":null,"HPA077773":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"}},{"Gene":"KCNIP1","Gene synonym":["KCHIP1"],"Ensembl":"ENSG00000182132","Gene description":"Potassium voltage-gated channel interacting protein 1","Uniprot":["Q9NZI2"],"Chromosome":"5","Position":"170353487-170736632","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"32.7","choroid plexus":"15.1","epididymis":"21.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Astrocytes":"56.0","Inhibitory neurons":"215.5","Microglial cells":"163.3","Oligodendrocyte precursor cells":"187.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"glioma":"22.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"22.9"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Skin - Fibroblast_1","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022864","HPA066717"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA022864":"AB_1858712","HPA066717":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"}},{"Gene":"KCNIP2","Gene synonym":["KCHIP2"],"Ensembl":"ENSG00000120049","Gene description":"Potassium voltage-gated channel interacting protein 2","Uniprot":["Q9NS61"],"Chromosome":"10","Position":"101825974-101843920","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"227.4","brain":"139.6","heart muscle":"307.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"47.6","Cardiomyocytes":"97.7","Cone photoreceptor cells":"24.1","Excitatory neurons":"23.0","Horizontal cells":"25.6","Inhibitory neurons":"41.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Skin - Adipocytes (Skin)"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"amygdala":"96.8","basal ganglia":"234.9","cerebral cortex":"106.9","hippocampal formation":"142.6","olfactory bulb":"144.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066717"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA066717":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-4"}},{"Gene":"KCNIP4","Gene synonym":["CALP","KCHIP4","MGC44947"],"Ensembl":"ENSG00000185774","Gene description":"Potassium voltage-gated channel interacting protein 4","Uniprot":["Q6PIL6"],"Chromosome":"4","Position":"20728606-21948772","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"24.5","retina":"18.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"9688.5","Inhibitory neurons":"1921.9","Oligodendrocyte precursor cells":"4956.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"1.2"},"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022862","HPA066717"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA022862":"AB_1852654","HPA066717":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"}},{"Gene":"KCNJ1","Gene synonym":["Kir1.1","ROMK1"],"Ensembl":"ENSG00000151704","Gene description":"Potassium inwardly rectifying channel subfamily J member 1","Uniprot":["P48048"],"Chromosome":"11","Position":"128836315-128867373","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Bartter syndrome","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"117","RNA tissue specific nTPM":{"kidney":"198.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"93","RNA single cell type specific nTPM":{"Collecting duct cells":"23.6","Distal tubular cells":"80.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"renal cancer":"3.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026962"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026962":"AB_10601934"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-3"}},{"Gene":"KCNJ10","Gene synonym":["Kir1.2","Kir4.1"],"Ensembl":"ENSG00000177807","Gene description":"Potassium inwardly rectifying channel subfamily J member 10","Uniprot":["P78508"],"Chromosome":"1","Position":"159998651-160070160","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Deafness","Disease variant","Epilepsy","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"100.7","kidney":"28.0","retina":"36.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"90.1","Muller glia cells":"67.2","Oligodendrocyte precursor cells":"34.2","Oligodendrocytes":"88.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"27.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"1.8"},"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Liver - Kupffer cells","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078302"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078302":"AB_2732378"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-3"}},{"Gene":"KCNJ11","Gene synonym":["BIR","Kir6.2"],"Ensembl":"ENSG00000187486","Gene description":"Potassium inwardly rectifying channel subfamily J member 11","Uniprot":["Q14654"],"Chromosome":"11","Position":"17385248-17389331","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Diabetes mellitus","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skeletal muscle":"134.7","tongue":"40.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"7.9","Cardiomyocytes":"19.8","Enteroendocrine cells":"6.4","Inhibitory neurons":"5.8","Skeletal myocytes":"13.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048891"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048891":"AB_2680547"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.56e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"}},{"Gene":"KCNJ12","Gene synonym":["hIRK1","IRK2","KCNJN1","Kir2.2","Kir2.2v"],"Ensembl":"ENSG00000184185","Gene description":"Potassium inwardly rectifying channel subfamily J member 12","Uniprot":["Q14500"],"Chromosome":"17","Position":"21376357-21419870","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"25.5","skeletal muscle":"69.1","tongue":"25.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"14.4","Horizontal cells":"30.8","Muller glia cells":"9.3","Skeletal myocytes":"19.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"25.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027021"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA027021":"AB_10602912"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.84e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"}},{"Gene":"KCNJ13","Gene synonym":["Kir1.4","Kir7.1","LCA16"],"Ensembl":"ENSG00000115474","Gene description":"Potassium inwardly rectifying channel subfamily J member 13","Uniprot":["O60928"],"Chromosome":"2","Position":"232765802-232776565","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Cataract","Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"choroid plexus":"159.5","intestine":"91.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Melanocytes":"29.6","Muller glia cells":"52.8","Proximal enterocytes":"222.3","Undifferentiated cells":"66.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"melanoma":"5.9"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"7.3","hippocampal formation":"8.0","thalamus":"5.3","white matter":"3.4"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051609"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA051609":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"}},{"Gene":"KCNJ14","Gene synonym":["IRK4","Kir2.4"],"Ensembl":"ENSG00000182324","Gene description":"Potassium inwardly rectifying channel subfamily J member 14","Uniprot":["Q9UNX9"],"Chromosome":"19","Position":"48455574-48466980","Protein class":["FDA approved drug targets","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"retina":"58.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"314.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071765"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA071765":"AB_2686444"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"}},{"Gene":"KCNJ15","Gene synonym":["IRKK","Kir1.3","Kir4.2"],"Ensembl":"ENSG00000157551","Gene description":"Potassium inwardly rectifying channel subfamily J member 15","Uniprot":["Q99712"],"Chromosome":"21","Position":"38155549-38307357","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"241.6","thyroid gland":"129.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"83.7","Cholangiocytes":"88.5","Early spermatids":"133.4","Late spermatids":"78.9","Proximal tubular cells":"200.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"29.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"20","RNA blood cell specific nTPM":{"neutrophil":"395.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"granulocytes":"395.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"21.6","head and neck cancer":"20.4"},"RNA tissue cell type enrichment":["Colon - Neutrophils","Heart muscle - Neutrophils","Kidney - Proximal tubular cells","Lung - Alveolar cells type 2","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016702"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA016702":"AB_1855560"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.09e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.95e-4"}},{"Gene":"KCNJ16","Gene synonym":["BIR9","Kir5.1"],"Ensembl":"ENSG00000153822","Gene description":"Potassium inwardly rectifying channel subfamily J member 16","Uniprot":["Q9NPI9"],"Chromosome":"17","Position":"70053429-70135608","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"kidney":"196.1","parathyroid gland":"269.2","thyroid gland":"139.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"29.5","Cholangiocytes":"46.2","Collecting duct cells":"198.9","Distal tubular cells":"43.5","Oligodendrocyte precursor cells":"52.5","Proximal tubular cells":"88.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"renal cancer":"37.2","thyroid cancer":"80.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"28.8","Sarcoma":"17.3"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059563"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059563":"AB_2684065"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.61e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.58e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"}},{"Gene":"KCNJ18","Gene synonym":["KIR2.6","TTPP2"],"Ensembl":"ENSG00000260458","Gene description":"Potassium inwardly rectifying channel subfamily J member 18","Uniprot":["B7U540"],"Chromosome":"17","Position":"21692523-21704612","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"7.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"0.8","head and neck cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027021"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA027021":"AB_10602912"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-5"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNJ2","Gene synonym":["IRK1","Kir2.1","LQT7"],"Ensembl":"ENSG00000123700","Gene description":"Potassium inwardly rectifying channel subfamily J member 2","Uniprot":["P63252"],"Chromosome":"17","Position":"70168673-70180044","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Atrial fibrillation","Disease variant","FDA approved drug targets","Long QT syndrome","Short QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"42.9","parathyroid gland":"36.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"36.8","Horizontal cells":"62.2","monocytes":"37.4","Oligodendrocytes":"155.5","Skeletal myocytes":"36.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"6.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"30.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"30.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"10.9"},"RNA tissue cell type enrichment":["Liver - Kupffer cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029109"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029109":"AB_10602913"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-3"}},{"Gene":"KCNJ3","Gene synonym":["GIRK1","KGA","Kir3.1"],"Ensembl":"ENSG00000162989","Gene description":"Potassium inwardly rectifying channel subfamily J member 3","Uniprot":["P48549"],"Chromosome":"2","Position":"154697855-154858354","Protein class":["FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"32.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"305.2","Inhibitory neurons":"421.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"breast cancer":"12.2","renal cancer":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"3.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Kidney - Ascending Loop of Henle cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024231","HPA064138"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA024231":"AB_1855558","HPA064138":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"}},{"Gene":"KCNJ4","Gene synonym":["HIR","hIRK2","HRK1","IRK3","Kir2.3"],"Ensembl":"ENSG00000168135","Gene description":"Potassium inwardly rectifying channel subfamily J member 4","Uniprot":["P48050"],"Chromosome":"22","Position":"38426327-38455199","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"brain":"28.9","heart muscle":"33.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"14.1","Horizontal cells":"7.7","Inhibitory neurons":"10.8","Microglial cells":"3.6","Muller glia cells":"7.4","Sertoli cells":"2.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.1","liver cancer":"1.8"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"amygdala":"10.5","basal ganglia":"18.9","cerebral cortex":"28.9","hippocampal formation":"21.9","white matter":"10.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"14","RNA pig brain regional specific nTPM":{"amygdala":"5.9","basal ganglia":"13.7","cerebral cortex":"14.7","hippocampal formation":"12.3","olfactory bulb":"15.9"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNJ5","Gene synonym":["CIR","GIRK4","KATP1","Kir3.4","LQT13"],"Ensembl":"ENSG00000120457","Gene description":"Potassium inwardly rectifying channel subfamily J member 5","Uniprot":["P48544"],"Chromosome":"11","Position":"128891356-128921163","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Cancer-related genes","Disease variant","Long QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"64.3","pancreas":"20.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal prostatic cells":"55.4","Hofbauer cells":"44.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Skin - Fibroblast_1"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"basal ganglia":"2.9","hypothalamus":"6.8","midbrain":"1.9","thalamus":"3.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014722","HPA017353","CAB022569"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022569":null,"HPA014722":"AB_1852133","HPA017353":"AB_1852135"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"}},{"Gene":"KCNJ6","Gene synonym":["BIR1","GIRK2","hiGIRK2","KATP2","KCNJ7","Kir3.2"],"Ensembl":"ENSG00000157542","Gene description":"Potassium inwardly rectifying channel subfamily J member 6","Uniprot":["P48051"],"Chromosome":"21","Position":"37607373-38121345","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Congenital generalized lipodystrophy","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"24.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"30.5","Enteroendocrine cells":"29.0","Excitatory neurons":"150.5","Horizontal cells":"101.3","Inhibitory neurons":"143.0","Oligodendrocyte precursor cells":"36.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"10.3","hippocampal formation":"10.6","midbrain":"24.2"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.2","eosinophil":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"granulocytes":"2.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"}},{"Gene":"KCNJ8","Gene synonym":["Kir6.1"],"Ensembl":"ENSG00000121361","Gene description":"Potassium inwardly rectifying channel subfamily J member 8","Uniprot":["Q15842"],"Chromosome":"12","Position":"21764955-21775600","Protein class":["Disease related genes","FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"71.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"15.7","Alveolar cells type 2":"19.4","Cardiomyocytes":"24.4","Hepatocytes":"23.0","Muller glia cells":"20.7","Sertoli cells":"74.6","Smooth muscle cells":"48.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"eosinophil":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"granulocytes":"1.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"7.9","liver cancer":"9.2","Neuroblastoma":"11.1"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Kidney - Fibroblasts","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031066"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031066":"AB_10602240"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.29e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"}},{"Gene":"KCNJ9","Gene synonym":["GIRK3","Kir3.3"],"Ensembl":"ENSG00000162728","Gene description":"Potassium inwardly rectifying channel subfamily J member 9","Uniprot":["Q92806"],"Chromosome":"1","Position":"160081538-160090563","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"65.8","choroid plexus":"20.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"11.6","Excitatory neurons":"23.2","Horizontal cells":"16.0","Inhibitory neurons":"12.2","Oligodendrocytes":"7.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"35","RNA cancer specific FPKM":{"glioma":"2.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"4.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070478"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA070478":"AB_2686270"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"}},{"Gene":"KCNK1","Gene synonym":["DPK","K2p1.1","TWIK-1"],"Ensembl":"ENSG00000135750","Gene description":"Potassium two pore domain channel subfamily K member 1","Uniprot":["O00180"],"Chromosome":"1","Position":"233614106-233672514","Protein class":["Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"58.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"155.6","Glandular and luminal cells":"85.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"69","RNA blood cell specific nTPM":{"plasmacytoid DC":"6.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"69","RNA blood lineage specific nTPM":{"dendritic cells":"6.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"117.0"},"Antibody":["HPA016049","CAB022588"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB022588":null,"HPA016049":"AB_1855571"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.84e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.29e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.69e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"}},{"Gene":"KCNK10","Gene synonym":["K2p10.1","PPP1R97","TREK-2","TREK2"],"Ensembl":"ENSG00000100433","Gene description":"Potassium two pore domain channel subfamily K member 10","Uniprot":["P57789"],"Chromosome":"14","Position":"88180103-88326907","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.1","intestine":"5.1","stomach 1":"2.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"52.0","Excitatory neurons":"43.2","Inhibitory neurons":"16.6","Oligodendrocyte precursor cells":"36.1","Oligodendrocytes":"11.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"62","RNA blood cell specific nTPM":{"plasmacytoid DC":"10.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"100","RNA blood lineage specific nTPM":{"dendritic cells":"10.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"2.6","Neuroblastoma":"2.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Proximal tubular cells","Skin - Outer root sheath cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030462"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030462":"AB_10601919"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-3"}},{"Gene":"KCNK12","Gene synonym":["K2p12.1","THIK-2","THIK2"],"Ensembl":"ENSG00000184261","Gene description":"Potassium two pore domain channel subfamily K member 12","Uniprot":["Q9HB15"],"Chromosome":"2","Position":"47509290-47570985","Protein class":["Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"brain":"7.0","pituitary gland":"3.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"11.1","Excitatory neurons":"18.7","Extravillous trophoblasts":"40.2","Inhibitory neurons":"29.7","Rod photoreceptor cells":"12.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"testis cancer":"2.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"2.6","lymphoma":"1.7","Myeloma":"1.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"}},{"Gene":"KCNK13","Gene synonym":["K2p13.1","THIK-1","THIK1"],"Ensembl":"ENSG00000152315","Gene description":"Potassium two pore domain channel subfamily K member 13","Uniprot":["Q9HB14"],"Chromosome":"14","Position":"90061994-90185853","Protein class":["Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"5.6","parathyroid gland":"6.0","testis":"9.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Microglial cells":"40.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"5.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"1.2"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"dendritic cells":"1.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"2.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003514"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nuclear speckles","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA003514":"AB_2666978"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"}},{"Gene":"KCNK15","Gene synonym":["dJ781B1.1","K2p15.1","KCNK11","KCNK14","KIAA0237","KT3.3","TASK-5","TASK5"],"Ensembl":"ENSG00000124249","Gene description":"Potassium two pore domain channel subfamily K member 15","Uniprot":["Q9H427"],"Chromosome":"20","Position":"44745865-44752313","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"15.4","Collecting duct cells":"9.8","Thymic epithelial cells":"44.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"ovarian cancer":"47.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"8.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"18","RNA mouse brain regional specific nTPM":{"olfactory bulb":"6.8"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"olfactory bulb":"3.9"},"Antibody":["HPA064861"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064861":"AB_2685373"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.68e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"}},{"Gene":"KCNK16","Gene synonym":["K2p16.1","TALK-1","TALK1"],"Ensembl":"ENSG00000095981","Gene description":"Potassium two pore domain channel subfamily K member 16","Uniprot":["Q96T55"],"Chromosome":"6","Position":"39314698-39322968","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"pancreas":"23.7","stomach 1":"10.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Pancreatic endocrine cells":"13.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"pancreatic cancer":"13.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"basophil":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"2.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"thyroid cancer":"10.4"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNK17","Gene synonym":["K2p17.1","TALK-2","TALK2","TASK-4","TASK4"],"Ensembl":"ENSG00000124780","Gene description":"Potassium two pore domain channel subfamily K member 17","Uniprot":["Q96T54"],"Chromosome":"6","Position":"39299001-39314461","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"7.7","thyroid gland":"6.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"35.6","Microglial cells":"17.3","Pancreatic endocrine cells":"18.9","Smooth muscle cells":"7.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"34","RNA blood cell specific nTPM":{"plasmacytoid DC":"63.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"34","RNA blood lineage specific nTPM":{"dendritic cells":"63.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"4.7","thyroid cancer":"3.3"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043892"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA043892":"AB_10962838"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-3"}},{"Gene":"KCNK18","Gene synonym":["K2p18.1","TRESK","TRESK-2","TRESK2","TRIK"],"Ensembl":"ENSG00000186795","Gene description":"Potassium two pore domain channel subfamily K member 18","Uniprot":["Q7Z418"],"Chromosome":"10","Position":"117197489-117210299","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"1.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044739"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044739":"AB_10795008"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNK2","Gene synonym":["K2p2.1","TREK-1"],"Ensembl":"ENSG00000082482","Gene description":"Potassium two pore domain channel subfamily K member 2","Uniprot":["O95069"],"Chromosome":"1","Position":"215005775-215237090","Protein class":["FDA approved drug targets","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"adrenal gland":"53.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Excitatory neurons":"19.4","Inhibitory neurons":"52.6","Microglial cells":"29.2","Oligodendrocyte precursor cells":"43.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-3"}},{"Gene":"KCNK3","Gene synonym":["K2p3.1","TASK","TASK-1","TASK1"],"Ensembl":"ENSG00000171303","Gene description":"Potassium two pore domain channel subfamily K member 3","Uniprot":["O14649"],"Chromosome":"2","Position":"26692690-26733420","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"181.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"68.1","Collecting duct cells":"104.4","Enteroendocrine cells":"28.5","Exocrine glandular cells":"81.9","Smooth muscle cells":"27.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"9.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"12.2","Neuroblastoma":"9.7","thyroid cancer":"13.2"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.37e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-3"}},{"Gene":"KCNK4","Gene synonym":["K2p4.1","TRAAK"],"Ensembl":"ENSG00000182450","Gene description":"Potassium two pore domain channel subfamily K member 4","Uniprot":["Q9NYG8"],"Chromosome":"11","Position":"64291302-64300031","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"brain":"6.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"2.8","Excitatory neurons":"8.9","Inhibitory neurons":"2.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNK5","Gene synonym":["K2p5.1","TASK-2","TASK2"],"Ensembl":"ENSG00000164626","Gene description":"Potassium two pore domain channel subfamily K member 5","Uniprot":["O95279"],"Chromosome":"6","Position":"39188971-39229475","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"35.4","kidney":"37.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"53.9","Cytotrophoblasts":"28.5","Distal enterocytes":"36.2","Proximal enterocytes":"56.4","Salivary duct cells":"35.5","Syncytiotrophoblasts":"41.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Proximal tubular cells","Lung - Alveolar cells type 2","Skin - Eccrine sweat gland cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059148"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA059148":"AB_2683929"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.29e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.85e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.98e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.45e-4"}},{"Gene":"KCNK6","Gene synonym":["K2p6.1","TWIK-2"],"Ensembl":"ENSG00000099337","Gene description":"Potassium two pore domain channel subfamily K member 6","Uniprot":["Q9Y257"],"Chromosome":"19","Position":"38319845-38332076","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"132.1","Suprabasal keratinocytes":"139.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"26.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"11.4","granulocytes":"26.2","monocytes":"7.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022637","HPA040184"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB022637":null,"HPA040184":"AB_2676876"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.45e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"}},{"Gene":"KCNK7","Gene synonym":["K2p7.1"],"Ensembl":"ENSG00000173338","Gene description":"Potassium two pore domain channel subfamily K member 7","Uniprot":["Q9Y2U2"],"Chromosome":"11","Position":"65592836-65595996","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"90.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"129.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"basophil":"2.1","naive B-cell":"2.2","neutrophil":"1.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"B-cells":"2.2","granulocytes":"2.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Esophageal cancer":"3.0"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077577"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA077577":"AB_2686845"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"}},{"Gene":"KCNK9","Gene synonym":["K2p9.1","TASK-3","TASK3"],"Ensembl":"ENSG00000169427","Gene description":"Potassium two pore domain channel subfamily K member 9","Uniprot":["Q9NPC2"],"Chromosome":"8","Position":"139600838-139704109","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["Disease variant","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"7.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"15.7","Horizontal cells":"10.9","Inhibitory neurons":"7.8","Late spermatids":"9.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"7.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"1.0","thyroid cancer":"1.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075842"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA075842":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"}},{"Gene":"KCNMA1","Gene synonym":["KCa1.1","mSLO1","SLO"],"Ensembl":"ENSG00000156113","Gene description":"Potassium calcium-activated channel subfamily M alpha 1","Uniprot":["Q12791"],"Chromosome":"10","Position":"76869601-77638369","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"138.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"456.4","Bipolar cells":"493.0","Excitatory neurons":"1009.1","Inhibitory neurons":"621.9","Oligodendrocyte precursor cells":"678.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"2.4","non-classical monocyte":"1.7"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"monocytes":"2.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"87.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Heart muscle - Smooth muscle cells","Prostate - Smooth muscle cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054648"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054648":"AB_2682556"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-3"}},{"Gene":"KCNMB1","Gene synonym":["hslo-beta"],"Ensembl":"ENSG00000145936","Gene description":"Potassium calcium-activated channel subfamily M regulatory beta subunit 1","Uniprot":["Q16558"],"Chromosome":"5","Position":"170374671-170389634","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"59.2","intestine":"75.1","smooth muscle":"53.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Peritubular cells":"361.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"6.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"5.7","monocytes":"5.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"3.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Colon - Smooth muscle cells","Heart muscle - Smooth muscle cells","Lung - Smooth muscle cells","Prostate - Smooth muscle cells","Skeletal muscle - Smooth muscle cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.13e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"}},{"Gene":"KCNMB2","Gene synonym":[],"Ensembl":"ENSG00000197584","Gene description":"Potassium calcium-activated channel subfamily M regulatory beta subunit 2","Uniprot":["Q9Y691"],"Chromosome":"3","Position":"178272932-178844429","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"35.4","fallopian tube":"13.9","ovary":"12.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Inhibitory neurons":"772.4","Oligodendrocyte precursor cells":"1898.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"3.9","lymphoma":"3.8"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Lung - Respiratory ciliated cells","Pancreas - Alpha cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022649"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022649":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"}},{"Gene":"KCNMB3","Gene synonym":["KCNMB2","KCNMBL"],"Ensembl":"ENSG00000171121","Gene description":"Potassium calcium-activated channel subfamily M regulatory beta subunit 3","Uniprot":["Q9NPA1"],"Chromosome":"3","Position":"179236691-179267002","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"9.2","Late spermatids":"11.2","Oligodendrocytes":"6.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015665","HPA019185"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA015665":"AB_1852142","HPA019185":"AB_1852144"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"}},{"Gene":"KCNMB4","Gene synonym":[],"Ensembl":"ENSG00000135643","Gene description":"Potassium calcium-activated channel subfamily M regulatory beta subunit 4","Uniprot":["Q86W47"],"Chromosome":"12","Position":"70366290-70434292","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"54.2","choroid plexus":"18.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"94.1","Inhibitory neurons":"44.1","Oligodendrocytes":"82.1","Schwann cells":"137.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"10.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"13.7"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Fibroblasts","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072287"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA072287":"AB_2686507"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"}},{"Gene":"KCNN1","Gene synonym":["hSK1","KCa2.1"],"Ensembl":"ENSG00000105642","Gene description":"Potassium calcium-activated channel subfamily N member 1","Uniprot":["Q92952"],"Chromosome":"19","Position":"17951293-18000080","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Transport"],"Molecular function":["Calmodulin-binding","Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"41","RNA tissue specific nTPM":{"brain":"92.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"12.7","Langerhans cells":"18.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"3.5"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"amygdala":"34.8","basal ganglia":"30.6","cerebral cortex":"67.2","hippocampal formation":"92.2","white matter":"30.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"22.7"},"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065938"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Actin filaments","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA065938":"AB_2685582"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"}},{"Gene":"KCNN2","Gene synonym":["hSK2","KCa2.2"],"Ensembl":"ENSG00000080709","Gene description":"Potassium calcium-activated channel subfamily N member 2","Uniprot":["Q9H2S1"],"Chromosome":"5","Position":"114055926-114496500","Protein class":["FDA approved drug targets","Plasma proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Transport"],"Molecular function":["Calmodulin-binding","Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"27.8","brain":"20.8","liver":"31.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"35.1","Excitatory neurons":"147.9","Inhibitory neurons":"94.9","Oligodendrocyte precursor cells":"60.7","Prostatic glandular cells":"30.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"3.5","melanoma":"3.2","prostate cancer":"12.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"20.5"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038221"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA038221":"AB_10673044"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-1"}},{"Gene":"KCNN3","Gene synonym":["hSK3","KCa2.3","SKCA3"],"Ensembl":"ENSG00000143603","Gene description":"Potassium calcium-activated channel subfamily N member 3","Uniprot":["Q9UGI6"],"Chromosome":"1","Position":"154697455-154870281","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Transport"],"Molecular function":["Calmodulin-binding","Ion channel"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"33.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"163.5","Endometrial ciliated cells":"28.6","Plasma cells":"41.5","Skeletal myocytes":"86.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"4.7","memory B-cell":"2.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"B-cells":"2.6","granulocytes":"4.7","monocytes":"1.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"lymphoma":"19.9","Myeloma":"34.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Enteric glia cells","Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017990","HPA057127"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017990":"AB_2669730","HPA057127":"AB_2683345"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.97e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"}},{"Gene":"KCNN4","Gene synonym":["hIKCa1","hKCa4","hSK4","IK","KCa3.1"],"Ensembl":"ENSG00000104783","Gene description":"Potassium calcium-activated channel subfamily N member 4","Uniprot":["O15554"],"Chromosome":"19","Position":"43766533-43781257","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Immunity","Ion transport","Transport"],"Molecular function":["Calmodulin-binding","Ion channel"],"Disease involvement":["Disease variant","FDA approved drug targets","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"130.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cytotrophoblasts":"225.5","Syncytiotrophoblasts":"793.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells (progenitors)","Skin - Eccrine sweat gland cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.9"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013367","HPA053841","HPA059622"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA013367":null,"HPA053841":"AB_2682278","HPA059622":"AB_2684085"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.68e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.56e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.75e-4"}},{"Gene":"KCNQ1","Gene synonym":["JLNS1","KCNA8","KCNA9","Kv7.1","KVLQT1","LQT","LQT1"],"Ensembl":"ENSG00000053918","Gene description":"Potassium voltage-gated channel subfamily Q member 1","Uniprot":["P51787"],"Chromosome":"11","Position":"2444684-2849105","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Calmodulin-binding","Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Atrial fibrillation","Deafness","Diabetes mellitus","Disease variant","FDA approved drug targets","Long QT syndrome","Short QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"197.1","stomach 1":"98.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"69.3","Undifferentiated cells":"53.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"42.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"30.2","Gastric cancer":"19.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Skeletal muscle - Macrophages","Stomach - Parietal cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018656","HPA048553","HPA071107"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB018656":"AB_2131551","HPA048553":"AB_2680438","HPA071107":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.85e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"}},{"Gene":"KCNQ2","Gene synonym":["BFNC","EBN","EBN1","ENB1","HNSPC","KCNA11","Kv7.2"],"Ensembl":"ENSG00000075043","Gene description":"Potassium voltage-gated channel subfamily Q member 2","Uniprot":["O43526"],"Chromosome":"20","Position":"63400208-63472677","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"91.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"18.3","Excitatory neurons":"60.9","Horizontal cells":"30.8","Inhibitory neurons":"36.7","Oligodendrocyte precursor cells":"48.6","Spermatogonia":"31.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"8.7"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"55.7","basal ganglia":"37.2","cerebellum":"27.8","cerebral cortex":"91.9","hippocampal formation":"68.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"46.5"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016642","HPA057112"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA016642":"AB_1855555","HPA057112":"AB_2683339"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"}},{"Gene":"KCNQ3","Gene synonym":["EBN2","Kv7.3"],"Ensembl":"ENSG00000184156","Gene description":"Potassium voltage-gated channel subfamily Q member 3","Uniprot":["O43525"],"Chromosome":"8","Position":"132120859-132481095","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"23.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"494.2","Inhibitory neurons":"473.6","Microglial cells":"488.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"}},{"Gene":"KCNQ4","Gene synonym":["DFNA2","Kv7.4"],"Ensembl":"ENSG00000117013","Gene description":"Potassium voltage-gated channel subfamily Q member 4","Uniprot":["P56696"],"Chromosome":"1","Position":"40783787-40840452","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Hearing","Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.1","intestine":"5.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"5.0","Inhibitory neurons":"9.4","Muller glia cells":"3.5","Skeletal myocytes":"5.9","Smooth muscle cells":"3.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"5.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Prostate - Smooth muscle cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018305"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018305":"AB_1855556"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"}},{"Gene":"KCNQ5","Gene synonym":["Kv7.5"],"Ensembl":"ENSG00000185760","Gene description":"Potassium voltage-gated channel subfamily Q member 5","Uniprot":["Q9NR82"],"Chromosome":"6","Position":"72621792-73198853","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"28.3","skeletal muscle":"21.1","tongue":"12.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Excitatory neurons":"2108.2","Inhibitory neurons":"843.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"28.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016655"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA016655":"AB_1855557"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"}},{"Gene":"KCNS1","Gene synonym":["Kv9.1"],"Ensembl":"ENSG00000124134","Gene description":"Potassium voltage-gated channel modifier subfamily S member 1","Uniprot":["Q96KK3"],"Chromosome":"20","Position":"45091214-45101127","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"22.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 2":"2.5","Cholangiocytes":"5.8","Excitatory neurons":"6.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"cervical cancer":"6.1"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"22.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"3.9"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.45e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"}},{"Gene":"KCNS2","Gene synonym":["Kv9.2"],"Ensembl":"ENSG00000156486","Gene description":"Potassium voltage-gated channel modifier subfamily S member 2","Uniprot":["Q9ULS6"],"Chromosome":"8","Position":"98426958-98432853","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"3.0","Excitatory neurons":"4.4","Horizontal cells":"3.2","Inhibitory neurons":"1.6","Leydig cells":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"4.7","white matter":"1.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"1.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051417"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051417":"AB_2681478"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"}},{"Gene":"KCNS3","Gene synonym":["Kv9.3"],"Ensembl":"ENSG00000170745","Gene description":"Potassium voltage-gated channel modifier subfamily S member 3","Uniprot":["Q9BQ31"],"Chromosome":"2","Position":"17877847-18361616","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lung":"23.5","skeletal muscle":"86.0","tongue":"45.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"32.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014864"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":["Golgi apparatus","Plasma membrane"],"Antibody RRID":{"HPA014864":"AB_1852155"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.53e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"}},{"Gene":"KCNT1","Gene synonym":["KCa4.1","KIAA1422","SLACK","Slo2.2"],"Ensembl":"ENSG00000107147","Gene description":"Potassium sodium-activated channel subfamily T member 1","Uniprot":["Q5JUK3"],"Chromosome":"9","Position":"135702185-135795508","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"37.1","lymphoid tissue":"15.8","skeletal muscle":"13.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"59.2","Inhibitory neurons":"53.7","Skeletal myocytes":"8.9","Theca cells":"14.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"0.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"37.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"5.7"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"42.8"},"Antibody":["HPA059880"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059880":"AB_2684149"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-13"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"}},{"Gene":"KCNT2","Gene synonym":["KCa4.2","SLICK","SLO2.1"],"Ensembl":"ENSG00000162687","Gene description":"Potassium sodium-activated channel subfamily T member 2","Uniprot":["Q6UVM3"],"Chromosome":"1","Position":"196225779-196609225","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"3.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"216.7","Inhibitory neurons":"234.2","Oligodendrocyte precursor cells":"297.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"4.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Fibroblasts","Prostate - Fibroblasts","Skin - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051218"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA051218":"AB_2681392"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"}},{"Gene":"KCNU1","Gene synonym":["KCa5.1","Kcnma3","KCNMC1","Slo3"],"Ensembl":"ENSG00000215262","Gene description":"Potassium calcium-activated channel subfamily U member 1","Uniprot":["A8MYU2"],"Chromosome":"8","Position":"36784324-36936125","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"testis":"7.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Early spermatids":"62.1","Late spermatids":"25.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"0.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063317"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA063317":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNV1","Gene synonym":["Kv8.1"],"Ensembl":"ENSG00000164794","Gene description":"Potassium voltage-gated channel modifier subfamily V member 1","Uniprot":["Q6PIU1"],"Chromosome":"8","Position":"109963636-109975771","Protein class":["Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"4.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Excitatory neurons":"27.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebral cortex":"36.6"},"Antibody":["HPA067233"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytokinetic bridge"],"Subcellular additional location":null,"Antibody RRID":{"HPA067233":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"KCNV2","Gene synonym":["Kv8.2"],"Ensembl":"ENSG00000168263","Gene description":"Potassium voltage-gated channel modifier subfamily V member 2","Uniprot":["Q8TDN2"],"Chromosome":"9","Position":"2717510-2730037","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"59","RNA tissue specific nTPM":{"retina":"289.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1544.1","Rod photoreceptor cells":"480.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"78","RNA cancer specific FPKM":{"testis cancer":"6.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031131"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031131":"AB_10609996"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"}},{"Gene":"KCTD3","Gene synonym":["NY-REN-45"],"Ensembl":"ENSG00000136636","Gene description":"Potassium channel tetramerization domain containing 3","Uniprot":["Q9Y597"],"Chromosome":"1","Position":"215567304-215621807","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"100.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015142"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015142":"AB_1852174"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.71e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.94e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-3"}},{"Gene":"KCTD7","Gene synonym":["CLN14","EPM3","FLJ32069"],"Ensembl":"ENSG00000243335","Gene description":"Potassium channel tetramerization domain containing 7","Uniprot":["Q96MP8"],"Chromosome":"7","Position":"66628881-66649067","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"65.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"40.4","Rod photoreceptor cells":"64.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.07e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"}},{"Gene":"KCTD8","Gene synonym":[],"Ensembl":"ENSG00000183783","Gene description":"Potassium channel tetramerization domain containing 8","Uniprot":["Q6ZWB6"],"Chromosome":"4","Position":"44173903-44448809","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"26.0","retina":"6.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"164.2","Excitatory neurons":"219.9","Inhibitory neurons":"435.3","Oligodendrocyte precursor cells":"309.0","Oligodendrocytes":"576.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.9","thyroid cancer":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"2.2","Neuroblastoma":"2.1"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031562"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA031562":"AB_10602609"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"}},{"Gene":"KDELR1","Gene synonym":["ERD2","ERD2.1","HDEL"],"Ensembl":"ENSG00000105438","Gene description":"KDEL endoplasmic reticulum protein retention receptor 1","Uniprot":["P24390"],"Chromosome":"19","Position":"48382575-48391551","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"671.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017455"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"CAB017455":"AB_10615208"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.49e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"}},{"Gene":"KDELR2","Gene synonym":["ELP-1","ERD2.2"],"Ensembl":"ENSG00000136240","Gene description":"KDEL endoplasmic reticulum protein retention receptor 2","Uniprot":["P33947"],"Chromosome":"7","Position":"6445953-6484190","Protein class":["Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"835.9","Extravillous trophoblasts":"1074.8","Syncytiotrophoblasts":"828.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016459"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016459":"AB_1852180"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.40e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.79e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"}},{"Gene":"KDELR3","Gene synonym":[],"Ensembl":"ENSG00000100196","Gene description":"KDEL endoplasmic reticulum protein retention receptor 3","Uniprot":["O43731"],"Chromosome":"22","Position":"38468078-38483447","Protein class":["Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"88.4","Fibroblasts":"49.0","Intestinal goblet cells":"57.4","Proximal enterocytes":"42.9","Serous glandular cells":"50.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Skin - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043477","HPA076405"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA043477":"AB_10962952","HPA076405":"AB_2686797"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.05e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"}},{"Gene":"KDM5B","Gene synonym":["CT31","JARID1B","PLU-1","PPP1R98","RBBP2H1A"],"Ensembl":"ENSG00000117139","Gene description":"Lysine demethylase 5B","Uniprot":["Q9UGL1"],"Chromosome":"1","Position":"202724495-202808487","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Dioxygenase","Oxidoreductase","Repressor"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"62.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"884.7","Spermatocytes":"422.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027179","HPA053723","CAB068193"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB068193":"AB_2665696","HPA027179":"AB_1851987","HPA053723":"AB_2682241"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"}},{"Gene":"KDM5D","Gene synonym":["HY","HYA","JARID1D","KIAA0234","SMCY"],"Ensembl":"ENSG00000012817","Gene description":"Lysine demethylase 5D","Uniprot":["Q9BY66"],"Chromosome":"Y","Position":"19703865-19744939","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Dioxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"50.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"27.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049086"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA049086":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.58e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"}},{"Gene":"KDM6A","Gene synonym":["UTX"],"Ensembl":"ENSG00000147050","Gene description":"Lysine demethylase 6A","Uniprot":["O15550"],"Chromosome":"X","Position":"44873188-45112779","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chromatin regulator","Dioxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"113.1","Oligodendrocyte precursor cells":"113.1","Oligodendrocytes":"249.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000568","HPA001165","HPA002111"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA000568":"AB_1858705","HPA001165":"AB_1080541","HPA002111":"AB_1858704"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"}},{"Gene":"KDM8","Gene synonym":["FLJ13798","JMJD5"],"Ensembl":"ENSG00000155666","Gene description":"Lysine demethylase 8","Uniprot":["Q8N371"],"Chromosome":"16","Position":"27203508-27221768","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Cell cycle","Transcription","Transcription regulation"],"Molecular function":["Aminopeptidase","Chromatin regulator","Dioxygenase","Hydrolase","Oxidoreductase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"80.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Hepatocytes":"59.3","Proximal enterocytes":"24.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026545"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA026545":"AB_1852015"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.75e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"}},{"Gene":"KDR","Gene synonym":["CD309","FLK1","VEGFR","VEGFR2"],"Ensembl":"ENSG00000128052","Gene description":"Kinase insert domain receptor","Uniprot":["P35968"],"Chromosome":"4","Position":"55078481-55125595","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Angiogenesis","Differentiation","Host-virus interaction"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Adipocytes":"140.4","Endothelial cells":"173.1","Muller glia cells":"175.5","Thymic epithelial cells":"197.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"27.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"52.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Sinusoid Endothelial cells","Skeletal muscle - Endothelial cells","Stomach - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004028","HPA073577"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"11000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"CAB004028":"AB_2212507","HPA073577":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.26e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"}},{"Gene":"KEL","Gene synonym":["CD238","ECE3"],"Ensembl":"ENSG00000197993","Gene description":"Kell metallo-endopeptidase (Kell blood group)","Uniprot":["P23276"],"Chromosome":"7","Position":"142941114-142962363","Protein class":["Blood group antigen proteins","Cancer-related genes","CD markers","Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Blood group antigen","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"56.3","testis":"32.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"62.8","Oligodendrocytes":"28.4","Sertoli cells":"22.1","Squamous epithelial cells":"16.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"Leukemia":"10.5"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064442"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA064442":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"}},{"Gene":"KHDC1","Gene synonym":["bA257K9.4","C6orf147","C6orf148","Em:AC019205.8","MGC10818","NDG1"],"Ensembl":"ENSG00000135314","Gene description":"KH domain containing 1","Uniprot":["Q4VXA5"],"Chromosome":"6","Position":"73241314-73310365","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"13.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"32.5","Inhibitory neurons":"30.0","Oligodendrocyte precursor cells":"27.9","Spermatocytes":"40.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029032"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029032":"AB_10602914"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-3"}},{"Gene":"KHK","Gene synonym":[],"Ensembl":"ENSG00000138030","Gene description":"Ketohexokinase","Uniprot":["P50053"],"Chromosome":"2","Position":"27086747-27100762","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"intestine":"121.2","kidney":"104.4","liver":"180.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"392.3","Proximal enterocytes":"1909.8","Proximal tubular cells":"748.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"liver cancer":"62.2","renal cancer":"32.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007040"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"620000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007040":"AB_1079185"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.62e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"}},{"Gene":"KIAA0040","Gene synonym":[],"Ensembl":"ENSG00000235750","Gene description":"KIAA0040","Uniprot":["Q15053"],"Chromosome":"1","Position":"175156986-175192999","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"100.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"123.7","Syncytiotrophoblasts":"429.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"59.5"},"RNA tissue cell type enrichment":["Stomach - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016895","HPA068812"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA016895":"AB_2669476","HPA068812":"AB_2686041"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"}},{"Gene":"KIAA0319","Gene synonym":["NMIG"],"Ensembl":"ENSG00000137261","Gene description":"KIAA0319","Uniprot":["Q5VV43"],"Chromosome":"6","Position":"24544104-24646191","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"12.3","pituitary gland":"4.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Astrocytes":"115.8","Early spermatids":"49.2","Excitatory neurons":"127.3","Inhibitory neurons":"71.0","Late spermatids":"102.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.6"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"granulocytes":"1.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015607","HPA076313"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA015607":"AB_1852299","HPA076313":"AB_2732308"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"}},{"Gene":"KIAA0319L","Gene synonym":["AAVR","KIAA1837"],"Ensembl":"ENSG00000142687","Gene description":"KIAA0319 like","Uniprot":["Q8IZA0"],"Chromosome":"1","Position":"35433492-35557950","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"47.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072692"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA072692":"AB_2686549"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.92e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.27e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"}},{"Gene":"KIAA0825","Gene synonym":["C5orf36","DKFZp686F0372","MGC34713"],"Ensembl":"ENSG00000185261","Gene description":"KIAA0825","Uniprot":["Q8IV33"],"Chromosome":"5","Position":"94152966-94618597","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"51.6","Excitatory neurons":"168.5","Inhibitory neurons":"164.7","Microglial cells":"54.7","Oligodendrocyte precursor cells":"60.7","Oligodendrocytes":"59.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"neutrophil":"12.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"granulocytes":"12.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"3.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038030","HPA038031"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038030":"AB_10672735","HPA038031":"AB_2675794"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"}},{"Gene":"KIAA1109","Gene synonym":["FLJ21404","FSA","KIAA1371","Tweek"],"Ensembl":"ENSG00000138688","Gene description":"KIAA1109","Uniprot":["Q2LD37"],"Chromosome":"4","Position":"122152331-122362758","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"237.6","Inhibitory neurons":"240.4","Oligodendrocytes":"226.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038076"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Nucleoplasm","Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA038076":"AB_10670652"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.33e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"}},{"Gene":"KIAA1549","Gene synonym":[],"Ensembl":"ENSG00000122778","Gene description":"KIAA1549","Uniprot":["Q9HCM3"],"Chromosome":"7","Position":"138831381-138981389","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"50.3","Excitatory neurons":"90.9","granulocytes":"77.0","Inhibitory neurons":"53.4","Oligodendrocyte precursor cells":"66.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"19.0"},"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019560"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"HPA019560":"AB_1852418"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"}},{"Gene":"KIAA1549L","Gene synonym":["C11orf41","C11orf69","G2","MGC34830"],"Ensembl":"ENSG00000110427","Gene description":"KIAA1549 like","Uniprot":["Q6ZVL6"],"Chromosome":"11","Position":"33376108-33674102","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"brain":"26.4","parathyroid gland":"33.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Excitatory neurons":"361.7","Inhibitory neurons":"189.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"4.4"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"141","RNA brain regional specific nTPM":{"amygdala":"8.6","basal ganglia":"14.9","cerebral cortex":"26.4","hippocampal formation":"12.3","white matter":"7.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010132","HPA051594"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA010132":"AB_1078313","HPA051594":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"KIAA2013","Gene synonym":["MGC33867","RP5-1077B9.1"],"Ensembl":"ENSG00000116685","Gene description":"KIAA2013","Uniprot":["Q8IYS2"],"Chromosome":"1","Position":"11919591-11926428","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"122.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052677","HPA060536"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA052677":"AB_2681911","HPA060536":"AB_2684313"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-3"}},{"Gene":"KIDINS220","Gene synonym":["ARMS"],"Ensembl":"ENSG00000134313","Gene description":"Kinase D interacting substrate 220","Uniprot":["Q9ULH0"],"Chromosome":"2","Position":"8721081-8837630","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurogenesis"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Intellectual disability","Neurodegeneration","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"304.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014790"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA014790":"AB_1852460"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.64e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.29e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"}},{"Gene":"KIF13A","Gene synonym":["bA500C11.2"],"Ensembl":"ENSG00000137177","Gene description":"Kinesin family member 13A","Uniprot":["Q9H1H9"],"Chromosome":"6","Position":"17759183-17987635","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Protein transport","Transport"],"Molecular function":["Motor protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"104.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"796.2","Oligodendrocytes":"428.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"5.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"5.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029253","HPA029254"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029253":"AB_10611115","HPA029254":"AB_10602094"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"}},{"Gene":"KIF1A","Gene synonym":["ATSV","C2orf20","SPG30","UNC104"],"Ensembl":"ENSG00000130294","Gene description":"Kinesin family member 1A","Uniprot":["Q12756"],"Chromosome":"2","Position":"240713761-240824293","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Intellectual disability","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"115.0","pancreas":"34.1","pituitary gland":"42.1","retina":"58.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"415.0","Cone photoreceptor cells":"115.5","Horizontal cells":"451.8","Muller glia cells":"106.4","Rod photoreceptor cells":"195.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"20.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"71.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005442"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Centriolar satellite","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA005442":"AB_1079210"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.97e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"}},{"Gene":"KIF3C","Gene synonym":[],"Ensembl":"ENSG00000084731","Gene description":"Kinesin family member 3C","Uniprot":["O14782"],"Chromosome":"2","Position":"25926598-25982749","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"75.5","retina":"19.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"52.7","Horizontal cells":"26.9","Inhibitory neurons":"44.8","Oligodendrocyte precursor cells":"26.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035755"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear bodies","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nuclear bodies","Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA035755":"AB_10602242"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.22e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.57e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"}},{"Gene":"KIFBP","Gene synonym":["DKFZP586B0923","KBP","KIAA1279","KIF1BP","TTC20"],"Ensembl":"ENSG00000198954","Gene description":"Kinesin family binding protein","Uniprot":["Q96EK5"],"Chromosome":"10","Position":"68988803-69043544","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Hirschsprung disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035538","HPA035539"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035538":"AB_10601130","HPA035539":"AB_2674676"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.60e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"KIFC1","Gene synonym":["HSET","KNSL2"],"Ensembl":"ENSG00000237649","Gene description":"Kinesin family member C1","Uniprot":["Q9BW19"],"Chromosome":"6","Position":"33391823-33409896","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Motor protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"39.7","lymphoid tissue":"47.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"33.6","Extravillous trophoblasts":"37.8","Late spermatids":"19.4","Plasma cells":"19.6","Undifferentiated cells":"22.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Mitotic cells (Colon)","Heart muscle - Mitotic cells (Heart)","Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Testis - Spermatocytes","Thyroid - Mitotic cells (Thyroid)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055997","HPA062674"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA055997":"AB_2683001","HPA062674":"AB_2684829"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.07e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.21e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-1"}},{"Gene":"KIR2DL1","Gene synonym":["47.11","CD158A","cl-42","nkat1","p58.1"],"Ensembl":"ENSG00000125498","Gene description":"Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1","Uniprot":["P43626"],"Chromosome":"19","Position":"54769793-54784322","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"2.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"NK-cells":"33.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Lung - NK-cells (Lung)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"KIR2DL3","Gene synonym":["CD158B2","cl-6","nkat2","nkat2a","nkat2b","p58"],"Ensembl":"ENSG00000243772","Gene description":"Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3","Uniprot":["P43628"],"Chromosome":"19","Position":"54738513-54753052","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"1.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"35","RNA single cell type specific nTPM":{"NK-cells":"16.6","Pancreatic endocrine cells":"5.2","T-cells":"4.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - NK-cells (Lung)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"}},{"Gene":"KIR2DL4","Gene synonym":["103AS","15.212","CD158D"],"Ensembl":"ENSG00000189013","Gene description":"Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4","Uniprot":["Q99706"],"Chromosome":"19","Position":"54803535-54814517","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lymphoid tissue":"4.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"NK-cells":"35.6","T-cells":"23.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"28","RNA blood cell specific nTPM":{"NK-cell":"2.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"28","RNA blood lineage specific nTPM":{"NK-cells":"2.8"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-5"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-3"}},{"Gene":"KIR3DL1","Gene synonym":["AMB11","CD158E1","CD158e1\/2","CD158e2","cl-11","cl-2","KIR","nkat3","NKB1","NKB1B"],"Ensembl":"ENSG00000167633","Gene description":"Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1","Uniprot":["P43629"],"Chromosome":"19","Position":"54816468-54830778","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"1.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"NK-cells":"21.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"gdT-cell":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"1.8"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - NK-cells (Lung)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"}},{"Gene":"KIR3DL2","Gene synonym":["CD158K","cl-5","nkat4","nkat4a","nkat4b"],"Ensembl":"ENSG00000240403","Gene description":"Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2","Uniprot":["P43630"],"Chromosome":"19","Position":"54850443-54867207","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"1.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"NK-cells":"38.0","T-cells":"11.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Lung - NK-cells (Lung)","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"}},{"Gene":"KIR3DL3","Gene synonym":["CD158Z","KIR3DL7","KIR44","KIRC1"],"Ensembl":"ENSG00000242019","Gene description":"Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3","Uniprot":[],"Chromosome":"19","Position":"54724479-54736536","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"KIRREL1","Gene synonym":["KIRREL","NEPH1"],"Ensembl":"ENSG00000183853","Gene description":"Kirre like nephrin family adhesion molecule 1","Uniprot":["Q96J84"],"Chromosome":"1","Position":"157993273-158100262","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"17.7","Fibroblasts":"17.9","Horizontal cells":"14.7","Inhibitory neurons":"21.3","Smooth muscle cells":"28.7","Thymic epithelial cells":"16.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030458"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"890000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030458":"AB_10601438"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.87e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.85e-4"}},{"Gene":"KIRREL2","Gene synonym":["DKFZp564A1164","FILTRIN","MGC15718","NEPH3","NLG1"],"Ensembl":"ENSG00000126259","Gene description":"Kirre like nephrin family adhesion molecule 2","Uniprot":["Q6UWL6"],"Chromosome":"19","Position":"35855861-35867136","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"pancreas":"70.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Bipolar cells":"53.6","Exocrine glandular cells":"14.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Podocytes","Stomach - Gastric enteroendocrine cells","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071587","HPA074326"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centriolar satellite"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"HPA071587":"AB_2732182","HPA074326":"AB_2732251"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"}},{"Gene":"KIRREL3","Gene synonym":["KIAA1867","KIRRE","NEPH2"],"Ensembl":"ENSG00000149571","Gene description":"Kirre like nephrin family adhesion molecule 3","Uniprot":["Q8IZU9"],"Chromosome":"11","Position":"126423358-127003460","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"21.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Excitatory neurons":"271.1","Inhibitory neurons":"469.6","Oligodendrocytes":"368.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"plasmacytoid DC":"8.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"8.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"7.5"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053324"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053324":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"}},{"Gene":"KISS1R","Gene synonym":["AXOR12","GPR54","HOT7T175"],"Ensembl":"ENSG00000116014","Gene description":"KISS1 receptor","Uniprot":["Q969F8"],"Chromosome":"19","Position":"917287-921005","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"8.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"52.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"10.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007156","HPA071913"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA007156":null,"HPA071913":"AB_2686471"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"}},{"Gene":"KIT","Gene synonym":["C-Kit","CD117","PBT","SCFR"],"Ensembl":"ENSG00000157404","Gene description":"KIT proto-oncogene, receptor tyrosine kinase","Uniprot":["P10721"],"Chromosome":"4","Position":"54657918-54740715","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"114.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"granulocytes":"528.4","Melanocytes":"391.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"28.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"20.3","eosinophil":"12.8","NK-cell":"13.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"20.3","NK-cells":"13.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"19.6","Leukemia":"32.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Lung - Mast cells","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003288","HPA004471","CAB068253","CAB072867","HPA073252"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"49000000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 5: Breast - Unknown function","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB003288":"AB_2335702","CAB068253":"AB_2665717","CAB072867":"AB_2665718","HPA004471":"AB_1078431","HPA073252":"AB_2686589"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"}},{"Gene":"KITLG","Gene synonym":["DFNA69","FPH2","Kitl","KL-1","MGF","SCF","SF","SLF"],"Ensembl":"ENSG00000049130","Gene description":"KIT ligand","Uniprot":["P21583"],"Chromosome":"12","Position":"88492793-88580851","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"48.0","Basal squamous epithelial cells":"57.6","Collecting duct cells":"74.8","Excitatory neurons":"46.0","Inhibitory neurons":"59.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070395"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA070395":"AB_2686264"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.01e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.81e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"KL","Gene synonym":[],"Ensembl":"ENSG00000133116","Gene description":"Klotho","Uniprot":["Q9UEF7"],"Chromosome":"13","Position":"33016423-33066143","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Glycosidase","Hormone","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"47.1","kidney":"128.7","parathyroid gland":"135.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Prostatic glandular cells":"41.0","Proximal tubular cells":"108.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"prostate cancer":"5.9","renal cancer":"17.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"2.0","Kidney cancer":"2.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"13.3","cerebral cortex":"6.7","hippocampal formation":"7.4","medulla oblongata":"4.2"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":510000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.44e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"KLB","Gene synonym":[],"Ensembl":"ENSG00000134962","Gene description":"Klotho beta","Uniprot":["Q86Z14"],"Chromosome":"4","Position":"39406930-39451533","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adipose tissue":"19.6","liver":"17.7","pancreas":"6.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"11.2","Enteroendocrine cells":"16.9","Hepatocytes":"43.5","Intestinal goblet cells":"16.7","Spermatocytes":"33.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"16","RNA cancer specific FPKM":{"liver cancer":"11.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"8.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021136"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021136":"AB_1852616"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"}},{"Gene":"KLC1","Gene synonym":["hKLC1B","hKLC1G","hKLC1J","hKLC1N","hKLC1P","hKLC1R","hKLC1S","KLC","KNS2","KNS2A"],"Ensembl":"ENSG00000126214","Gene description":"Kinesin light chain 1","Uniprot":["Q07866"],"Chromosome":"14","Position":"103561896-103714249","Protein class":["Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Motor protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"397.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"169.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009798","HPA044617","HPA052450"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB009798":"AB_2280879","HPA044617":"AB_2679024","HPA052450":"AB_2681838"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.75e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.17e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"}},{"Gene":"KLHDC4","Gene synonym":["DKFZp434G0522"],"Ensembl":"ENSG00000104731","Gene description":"Kelch domain containing 4","Uniprot":["Q8TBB5"],"Chromosome":"16","Position":"87696485-87765992","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"85.4","NK-cells":"64.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041665"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Kinetochore"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Kinetochore"],"Antibody RRID":{"HPA041665":"AB_10796352"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.69e-4"}},{"Gene":"KLHDC7A","Gene synonym":["FLJ38753"],"Ensembl":"ENSG00000179023","Gene description":"Kelch domain containing 7A","Uniprot":["Q5VTJ3"],"Chromosome":"1","Position":"18480930-18485974","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"8.4","kidney":"19.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"7.7","Collecting duct cells":"7.9","Endometrial ciliated cells":"4.5","Gastric mucus-secreting cells":"6.6","Hepatocytes":"7.0","Proximal tubular cells":"8.0","Respiratory ciliated cells":"6.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"10.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"9.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056616"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA056616":"AB_2683193"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.81e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.88e-4"}},{"Gene":"KLHDC9","Gene synonym":["KARCA1"],"Ensembl":"ENSG00000162755","Gene description":"Kelch domain containing 9","Uniprot":["Q8NEP7"],"Chromosome":"1","Position":"161098361-161100346","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"29.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"426.8","Late spermatids":"464.0","Spermatocytes":"178.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043197"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim","Mitotic chromosome"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nucleoli","Nucleoli rim","Mitotic chromosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA043197":"AB_2678359"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.20e-6"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"}},{"Gene":"KLHL14","Gene synonym":["KIAA1384"],"Ensembl":"ENSG00000197705","Gene description":"Kelch like family member 14","Uniprot":["Q9P2G3"],"Chromosome":"18","Position":"32672673-32773023","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"seminal vesicle":"12.7","thyroid gland":"13.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"17.8","Basal prostatic cells":"7.5","Inhibitory neurons":"9.6","Muller glia cells":"19.6","Plasma cells":"39.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"endometrial cancer":"6.8","ovarian cancer":"15.5","thyroid cancer":"7.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"90","RNA blood cell specific nTPM":{"memory B-cell":"10.5","naive B-cell":"7.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"106","RNA blood lineage specific nTPM":{"B-cells":"10.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"10.4","ovarian cancer":"12.4"},"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"9","RNA pig brain regional specific nTPM":{"hippocampal formation":"14.9","olfactory bulb":"8.1"},"Antibody":["HPA024777"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA024777":"AB_1852576"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"}},{"Gene":"KLHL26","Gene synonym":[],"Ensembl":"ENSG00000167487","Gene description":"Kelch like family member 26","Uniprot":["Q53HC5"],"Chromosome":"19","Position":"18637025-18671721","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023074"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023074":"AB_2671060"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"}},{"Gene":"KLHL42","Gene synonym":["Ctb9","KIAA1340","KLHDC5"],"Ensembl":"ENSG00000087448","Gene description":"Kelch like family member 42","Uniprot":["Q9P2K6"],"Chromosome":"12","Position":"27780048-27803040","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Peritubular cells":"167.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020979"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA020979":"AB_1852559"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.98e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"}},{"Gene":"KLK11","Gene synonym":["PRSS20","TLSP"],"Ensembl":"ENSG00000167757","Gene description":"Kallikrein related peptidase 11","Uniprot":["Q9UBX7"],"Chromosome":"19","Position":"51022216-51028039","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"324.2","skin 1":"239.8","vagina":"186.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"213.6","Club cells":"277.7","Ionocytes":"235.2","Late spermatids":"357.1","Squamous epithelial cells":"216.3","Suprabasal keratinocytes":"650.5","Thymic epithelial cells":"309.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"53.3"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"1.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"99.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 1","Skin - Keratinocyte (other)","Testis - Late spermatids","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026340"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026340":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.78e-4"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.17e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"}},{"Gene":"KLRB1","Gene synonym":["CD161","CLEC5B","hNKR-P1A","NKR","NKR-P1","NKR-P1A"],"Ensembl":"ENSG00000111796","Gene description":"Killer cell lectin like receptor B1","Uniprot":["Q12918"],"Chromosome":"12","Position":"9594551-9607916","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"47.4","lymphoid tissue":"36.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"NK-cells":"1508.8","T-cells":"767.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"2177.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"140","RNA blood lineage specific nTPM":{"NK-cells":"756.7","T-cells":"2177.1"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - NK-cells (Liver)","Lung - NK-cells (Lung)","Pancreas - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039113"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA039113":"AB_10674979"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.51e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.42e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.99e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.61e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"}},{"Gene":"KLRC1","Gene synonym":["CD159a","NKG2","NKG2-A","NKG2-B"],"Ensembl":"ENSG00000134545","Gene description":"Killer cell lectin like receptor C1","Uniprot":["P26715"],"Chromosome":"12","Position":"10442264-10454685","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"6.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"NK-cells":"229.4","T-cells":"105.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"gdT-cell":"229.2","NK-cell":"367.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"46","RNA blood lineage specific nTPM":{"NK-cells":"367.6","T-cells":"229.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Liver - NK-cells (Liver)","Pancreas - T-cells","Prostate - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058052"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA058052":"AB_2683589"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-3"}},{"Gene":"KLRC2","Gene synonym":["CD159c","NKG2-C"],"Ensembl":"ENSG00000205809","Gene description":"Killer cell lectin like receptor C2","Uniprot":["P26717"],"Chromosome":"12","Position":"10426854-10442300","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"9.4","lymphoid tissue":"5.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"NK-cells":"77.8","Oligodendrocyte precursor cells":"31.3","T-cells":"59.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"24.6","NK-cell":"84.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"103","RNA blood lineage specific nTPM":{"NK-cells":"84.5","T-cells":"24.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"15.9"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058052"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA058052":"AB_2683589"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"}},{"Gene":"KLRC3","Gene synonym":["NKG2-E"],"Ensembl":"ENSG00000205810","Gene description":"Killer cell lectin like receptor C3","Uniprot":["Q07444"],"Chromosome":"12","Position":"10412315-10420595","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1.9","brain":"2.1","lymphoid tissue":"4.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"NK-cells":"17.4","Oligodendrocyte precursor cells":"34.7","T-cells":"9.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"NK-cell":"63.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"NK-cells":"63.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"6.8","thyroid cancer":"5.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Lung - NK-cells (Lung)","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039910","HPA062570"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA039910":null,"HPA062570":"AB_2684795"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"KLRC4","Gene synonym":["NKG2-F"],"Ensembl":"ENSG00000183542","Gene description":"Killer cell lectin like receptor C4","Uniprot":["O43908"],"Chromosome":"12","Position":"10407382-10409757","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"9.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"NK-cells":"25.4","T-cells":"13.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"20","RNA blood cell specific nTPM":{"gdT-cell":"8.2","memory CD8 T-cell":"5.9","naive CD8 T-cell":"6.7","NK-cell":"4.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"59","RNA blood lineage specific nTPM":{"NK-cells":"4.7","T-cells":"8.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"8.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Kidney - T-cells","Pancreas - T-cells","Prostate - T-cells","Stomach - T-cells","Testis - Early spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-3"}},{"Gene":"KLRD1","Gene synonym":["CD94"],"Ensembl":"ENSG00000134539","Gene description":"Killer cell lectin like receptor D1","Uniprot":["Q13241"],"Chromosome":"12","Position":"10226058-10329608","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"17.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"NK-cells":"1409.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"gdT-cell":"512.6","memory CD8 T-cell":"217.7","naive CD8 T-cell":"218.7","NK-cell":"737.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"68","RNA blood lineage specific nTPM":{"NK-cells":"737.5","T-cells":"512.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Heart muscle - T-cells","Liver - NK-cells (Liver)","Lung - NK-cells (Lung)","Prostate - T-cells","Stomach - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069688"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069688":"AB_2686170"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"}},{"Gene":"KLRF1","Gene synonym":["CLEC5C","NKp80"],"Ensembl":"ENSG00000150045","Gene description":"Killer cell lectin like receptor F1","Uniprot":["Q9NZS2"],"Chromosome":"12","Position":"9827481-9845007","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"12.8","lymphoid tissue":"18.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"NK-cells":"681.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"NK-cell":"664.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"NK-cells":"664.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Liver - NK-cells (Liver)","Lung - NK-cells (Lung)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054038"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA054038":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-3"}},{"Gene":"KLRF2","Gene synonym":["NKp65"],"Ensembl":"ENSG00000256797","Gene description":"Killer cell lectin like receptor F2","Uniprot":["D3W0D1"],"Chromosome":"12","Position":"9881489-9895833","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"skin 1":"11.9"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"32","RNA blood cell specific nTPM":{"NK-cell":"3.1","plasmacytoid DC":"3.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"dendritic cells":"3.2","NK-cells":"3.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"43","RNA cell line specific nTPM":{"Leukemia":"4.1","lymphoma":"1.7","Myeloma":"6.9"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"KLRG1","Gene synonym":["2F1","CLEC15A","MAFA","MAFA-L"],"Ensembl":"ENSG00000139187","Gene description":"Killer cell lectin like receptor G1","Uniprot":["Q96E93"],"Chromosome":"12","Position":"8950044-9010760","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"10.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"granulocytes":"72.9","NK-cells":"126.9","T-cells":"96.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"390.9","MAIT T-cell":"461.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"T-cells":"461.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Fibroblasts","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051403","HPA076494"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA051403":null,"HPA076494":"AB_2686800"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"}},{"Gene":"KLRG2","Gene synonym":["CLEC15B","FLJ44186"],"Ensembl":"ENSG00000188883","Gene description":"Killer cell lectin like receptor G2","Uniprot":["A4D1S0"],"Chromosome":"7","Position":"139452690-139483673","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"4.0","salivary gland":"4.3","thyroid gland":"4.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"7.0","Basal squamous epithelial cells":"9.6","Collecting duct cells":"5.9","Erythroid cells":"4.3","Squamous epithelial cells":"14.1","Syncytiotrophoblasts":"6.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"testis cancer":"42.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"11.4"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018199"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA018199":"AB_2133260"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-8"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.61e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"}},{"Gene":"KLRK1","Gene synonym":["CD314","D12S2489E","KLR","NKG2-D","NKG2D"],"Ensembl":"ENSG00000213809","Gene description":"Killer cell lectin like receptor K1","Uniprot":["P26718"],"Chromosome":"12","Position":"10372353-10391874","Protein class":["Cancer-related genes","CD markers","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Differentiation","Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"22.1","lymphoid tissue":"42.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"NK-cells":"26.5","T-cells":"41.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"40","RNA blood cell specific nTPM":{"gdT-cell":"287.4","MAIT T-cell":"111.5","memory CD8 T-cell":"261.2","naive CD8 T-cell":"258.8","NK-cell":"335.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"50","RNA blood lineage specific nTPM":{"NK-cells":"335.8","T-cells":"287.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"Leukemia":"10.3","lymphoma":"33.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - NK-cells (Liver)","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB021896","HPA068877"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"47000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB021896":null,"HPA068877":"AB_2686052"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-10"}},{"Gene":"KMO","Gene synonym":[],"Ensembl":"ENSG00000117009","Gene description":"Kynurenine 3-monooxygenase","Uniprot":["O15229"],"Chromosome":"1","Position":"241532134-241595642","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Pyridine nucleotide biosynthesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"kidney":"31.5","liver":"91.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"273.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"breast cancer":"1.6","liver cancer":"3.3","renal cancer":"3.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"79","RNA blood cell specific nTPM":{"classical monocyte":"11.0","intermediate monocyte":"32.3","memory B-cell":"36.1","myeloid DC":"11.3","naive B-cell":"42.0","non-classical monocyte":"33.8","plasmacytoid DC":"24.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"97","RNA blood lineage specific nTPM":{"B-cells":"42.0","dendritic cells":"24.3","monocytes":"33.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bone cancer":"28.7","breast cancer":"7.9","Kidney cancer":"10.0","lymphoma":"9.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Kidney - Proximal tubular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"thalamus":"1.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031115","HPA056942"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031115":"AB_10601924","HPA056942":"AB_2683281"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.49e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"}},{"Gene":"KMT2E","Gene synonym":["HDCMC04P","MLL5"],"Ensembl":"ENSG00000005483","Gene description":"Lysine methyltransferase 2E (inactive)","Uniprot":["Q8IZD2"],"Chromosome":"7","Position":"105014190-105115019","Protein class":["Disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Growth arrest","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042866","HPA056125"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA042866":null,"HPA056125":"AB_2683044"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.80e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"KNCN","Gene synonym":["FLJ32011","KINO","L5"],"Ensembl":"ENSG00000162456","Gene description":"Kinocilin","Uniprot":["A6PVL3"],"Chromosome":"1","Position":"46545641-46551647","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"3.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"48","RNA single cell type specific nTPM":{"Early spermatids":"13.5","Late spermatids":"32.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"hypothalamus":"3.3","medulla oblongata":"1.8","midbrain":"2.3","pons":"2.0","thalamus":"1.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"KNTC1","Gene synonym":["KIAA0166","ROD"],"Ensembl":"ENSG00000184445","Gene description":"Kinetochore associated 1","Uniprot":["P50748"],"Chromosome":"12","Position":"122527246-122626396","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"42.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"25.1","Erythroid cells":"23.9","Late spermatids":"21.3","Plasma cells":"30.1","Spermatocytes":"46.1","Spermatogonia":"32.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Mitotic cells (Stomach)","Testis - Spermatocytes","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025241"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA025241":"AB_1852629"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.69e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.79e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.89e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"}},{"Gene":"KPNB1","Gene synonym":["IMB1","Impnb","IPO1","IPOB","MGC2155","MGC2156","MGC2157","NTF97"],"Ensembl":"ENSG00000108424","Gene description":"Karyopherin subunit beta 1","Uniprot":["Q14974"],"Chromosome":"17","Position":"47649476-47685505","Protein class":["Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":["Host-virus interaction","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029878","CAB034449","HPA050302"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB034449":"AB_2133993","HPA029878":"AB_10670041","HPA050302":"AB_2681079"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.55e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.43e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"}},{"Gene":"KREMEN1","Gene synonym":["KREMEN","KRM1"],"Ensembl":"ENSG00000183762","Gene description":"Kringle containing transmembrane protein 1","Uniprot":["Q96MU8"],"Chromosome":"22","Position":"29073035-29168333","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"57.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"1.3","neutrophil":"4.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"4.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058513"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA058513":"AB_2683739"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"KREMEN2","Gene synonym":["KRM2","MGC10791"],"Ensembl":"ENSG00000131650","Gene description":"Kringle containing transmembrane protein 2","Uniprot":["Q8NCW0"],"Chromosome":"16","Position":"2964216-2968383","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"4.1","skin 1":"7.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"8.7","Basal squamous epithelial cells":"10.8","Cone photoreceptor cells":"10.3","Intestinal goblet cells":"15.5","Rod photoreceptor cells":"12.4","Spermatocytes":"14.9","Spermatogonia":"11.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.2","naive B-cell":"1.3"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"B-cells":"1.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"37.6"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003223"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA003223":"AB_1079217"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.98e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-3"}},{"Gene":"KRT79","Gene synonym":["K6L","KRT6L"],"Ensembl":"ENSG00000185640","Gene description":"Keratin 79","Uniprot":["Q5XKE5"],"Chromosome":"12","Position":"52821408-52834311","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"20","RNA tissue specific nTPM":{"skin 1":"68.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"2.0","Late spermatids":"1.4","Melanocytes":"3.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"breast cancer":"1.4","cervical cancer":"2.6","head and neck cancer":"2.7","melanoma":"1.6","urothelial cancer":"3.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"5.0","Sarcoma":"2.5"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059347"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1900000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059347":"AB_2683986"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"}},{"Gene":"KRTCAP2","Gene synonym":["KCP2"],"Ensembl":"ENSG00000163463","Gene description":"Keratinocyte associated protein 2","Uniprot":["Q8N6L1"],"Chromosome":"1","Position":"155169408-155173475","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"470.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.70e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-3"}},{"Gene":"KRTCAP3","Gene synonym":["KCP3"],"Ensembl":"ENSG00000157992","Gene description":"Keratinocyte associated protein 3","Uniprot":["Q53RY4"],"Chromosome":"2","Position":"27442366-27446481","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"149.5","Proximal enterocytes":"172.8","Undifferentiated cells":"175.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"MAIT T-cell":"6.8","memory B-cell":"4.5","memory CD4 T-cell":"5.6","memory CD8 T-cell":"2.6","naive B-cell":"6.4","naive CD4 T-cell":"6.6","naive CD8 T-cell":"2.7","T-reg":"4.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"B-cells":"6.4","T-cells":"6.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047136","HPA060203"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA047136":"AB_2679949","HPA060203":"AB_2684221"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.67e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-3"}},{"Gene":"KTN1","Gene synonym":["CG1","KIAA0004","KNT"],"Ensembl":"ENSG00000126777","Gene description":"Kinectin 1","Uniprot":["Q86UP2"],"Chromosome":"14","Position":"55559072-55701526","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1591.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003178","CAB015331","HPA017876"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB015331":null,"HPA003178":"AB_1079218","HPA017876":"AB_1852652"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.83e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.76e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.01e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"KXD1","Gene synonym":["BORCS4","C19orf50","FLJ25480","KXDL","MGC2749"],"Ensembl":"ENSG00000105700","Gene description":"KxDL motif containing 1","Uniprot":["Q9BQD3"],"Chromosome":"19","Position":"18557762-18569387","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041507","HPA041599"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoli fibrillar center","Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041507":"AB_10795698","HPA041599":"AB_10795502"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.46e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.71e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"}},{"Gene":"L1CAM","Gene synonym":["CD171","HSAS","HSAS1","MASA","MIC5","S10","SPG1"],"Ensembl":"ENSG00000198910","Gene description":"L1 cell adhesion molecule","Uniprot":["P32004"],"Chromosome":"X","Position":"153861514-153886173","Protein class":["CD markers","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Hirschsprung disease","Intellectual disability","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"42.8","intestine":"48.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"72.9","Horizontal cells":"40.4","Melanocytes":"59.2","Schwann cells":"202.5","Sertoli cells":"38.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"34.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010896"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"67000000","Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010896":"AB_609903"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.51e-10"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.81e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.36e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.17e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-3"}},{"Gene":"L2HGDH","Gene synonym":["C14orf160","FLJ12618"],"Ensembl":"ENSG00000087299","Gene description":"L-2-hydroxyglutarate dehydrogenase","Uniprot":["Q9H9P8"],"Chromosome":"14","Position":"50237563-50312229","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"42.5","Excitatory neurons":"59.7","Inhibitory neurons":"60.0","Rod photoreceptor cells":"43.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"8.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Kidney - Proximal tubular cells","Liver - Hepatocytes","Skin - Keratinocyte (other)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065409","HPA069708"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA065409":"AB_2685485","HPA069708":"AB_2686179"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.75e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"}},{"Gene":"L3MBTL3","Gene synonym":["KIAA1798"],"Ensembl":"ENSG00000198945","Gene description":"L3MBTL histone methyl-lysine binding protein 3","Uniprot":["Q96JM7"],"Chromosome":"6","Position":"130013699-130141449","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044382","HPA053035"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA044382":"AB_2678920","HPA053035":"AB_2682021"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"}},{"Gene":"LACTB","Gene synonym":["FLJ14902","MRPL56"],"Ensembl":"ENSG00000103642","Gene description":"Lactamase beta","Uniprot":["P83111"],"Chromosome":"15","Position":"63121833-63142061","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"120.9","Spermatocytes":"119.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036361","HPA036362"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA036361":"AB_10672244","HPA036362":"AB_10670798"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"}},{"Gene":"LAG3","Gene synonym":["CD223"],"Ensembl":"ENSG00000089692","Gene description":"Lymphocyte activating 3","Uniprot":["P18627"],"Chromosome":"12","Position":"6772512-6778455","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"23.6","ovary":"18.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"39.2","Peritubular cells":"66.1","T-cells":"50.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"12.6","MAIT T-cell":"10.0","memory CD8 T-cell":"11.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"49","RNA blood lineage specific nTPM":{"T-cells":"12.6"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"12.3"},"RNA tissue cell type enrichment":["Breast - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002301","HPA013967"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002301":"AB_564101","HPA013967":"AB_1846277"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.89e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.62e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-3"}},{"Gene":"LAIR1","Gene synonym":["CD305"],"Ensembl":"ENSG00000167613","Gene description":"Leukocyte associated immunoglobulin like receptor 1","Uniprot":["Q6GTX8"],"Chromosome":"19","Position":"54351384-54370558","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"28.1","lymphoid tissue":"46.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"146.7","granulocytes":"66.1","Hofbauer cells":"191.3","Kupffer cells":"83.7","Macrophages":"128.4","monocytes":"80.2","NK-cells":"63.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"4.3","Myeloma":"2.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Lung - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011155"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"350000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA011155":"AB_1852685"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"}},{"Gene":"LAMA3","Gene synonym":["BM600-150kDa","epiligrin","kalinin-165kDa","LAMNA","nicein-150kDa"],"Ensembl":"ENSG00000053747","Gene description":"Laminin subunit alpha 3","Uniprot":["Q16787"],"Chromosome":"18","Position":"23689453-23956222","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Epidermolysis bullosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"129.4","Basal respiratory cells":"107.2","Distal enterocytes":"83.3","Gastric mucus-secreting cells":"123.4","Paneth cells":"85.5","Salivary duct cells":"76.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"40.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"149.4"},"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009309","CAB010757"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB010757":"AB_477162","HPA009309":"AB_1079224"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.58e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"}},{"Gene":"LAMC3","Gene synonym":["DKFZp434E202"],"Ensembl":"ENSG00000050555","Gene description":"Laminin subunit gamma 3","Uniprot":["Q9Y6N6"],"Chromosome":"9","Position":"131009174-131094473","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"48.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Leydig cells":"113.2","Peritubular cells":"366.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"8.9"},"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Testis - Peritubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022814"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA022814":"AB_2670960"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"}},{"Gene":"LAMP1","Gene synonym":["CD107a"],"Ensembl":"ENSG00000185896","Gene description":"Lysosomal associated membrane protein 1","Uniprot":["P11279"],"Chromosome":"13","Position":"113297239-113323672","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"742.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Lung - Macrophages","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004260","HPA014750"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004260":"AB_626851","HPA014750":"AB_1846219"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"}},{"Gene":"LAMP2","Gene synonym":["CD107b"],"Ensembl":"ENSG00000005893","Gene description":"Lysosomal associated membrane protein 2","Uniprot":["P13473"],"Chromosome":"X","Position":"120426148-120469365","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"478.8","Syncytiotrophoblasts":"491.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"556.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"556.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005272","HPA029100"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"520000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB005272":"AB_647855","HPA029100":"AB_10795022"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"}},{"Gene":"LAMP3","Gene synonym":["CD208","DC-LAMP","DCLAMP","LAMP","TSC403"],"Ensembl":"ENSG00000078081","Gene description":"Lysosomal associated membrane protein 3","Uniprot":["Q9UQV4"],"Chromosome":"3","Position":"183122215-183163839","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lung":"219.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Alveolar cells type 2":"437.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"27.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"5.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"5.6","T-cells":"4.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025133","HPA051467"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"59000","Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB025133":null,"HPA051467":"AB_2681495"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.90e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.89e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"}},{"Gene":"LAMP5","Gene synonym":["BAD-LAMP","C20orf103","dJ1119D9.3","UNC-46"],"Ensembl":"ENSG00000125869","Gene description":"Lysosomal associated membrane protein family member 5","Uniprot":["Q9UJQ1"],"Chromosome":"20","Position":"9514358-9530524","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"96.6","retina":"29.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"197.5","Horizontal cells":"51.3","Inhibitory neurons":"38.0","Plasma cells":"28.3","Theca cells":"45.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"plasmacytoid DC":"141.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"31","RNA blood lineage specific nTPM":{"dendritic cells":"141.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"57.0","Myeloma":"88.1","Neuroblastoma":"32.3"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004802","HPA070765"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitotic spindle","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Mitotic spindle","Centriolar satellite"],"Antibody RRID":{"HPA004802":"AB_10603682","HPA070765":"AB_2686309"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.46e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"}},{"Gene":"LAPTM4A","Gene synonym":["HUMORF13","KIAA0108","LAPTM4","MBNT","Mtrp"],"Ensembl":"ENSG00000068697","Gene description":"Lysosomal protein transmembrane 4 alpha","Uniprot":["Q15012"],"Chromosome":"2","Position":"20032650-20051628","Protein class":["Predicted membrane proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031402","HPA031404","HPA068554"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA031402":"AB_10669882","HPA031404":"AB_10670293","HPA068554":"AB_2686003"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.37e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"}},{"Gene":"LAPTM4B","Gene synonym":["LC27"],"Ensembl":"ENSG00000104341","Gene description":"Lysosomal protein transmembrane 4 beta","Uniprot":["Q86VI4"],"Chromosome":"8","Position":"97775057-97853013","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"380.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"806.5","Granulosa cells":"338.9","Rod photoreceptor cells":"525.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"3.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"3.3","T-cells":"1.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020782","HPA068830"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB020782":null,"HPA068830":"AB_2686044"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.63e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.70e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.70e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"}},{"Gene":"LAPTM5","Gene synonym":[],"Ensembl":"ENSG00000162511","Gene description":"Lysosomal protein transmembrane 5","Uniprot":["Q13571"],"Chromosome":"1","Position":"30732469-30757774","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1285.7","lymphoid tissue":"672.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"876.2","dendritic cells":"488.5","granulocytes":"661.3","Hofbauer cells":"1304.4","Kupffer cells":"804.8","Langerhans cells":"566.9","Macrophages":"910.5","monocytes":"1416.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Leukemia":"486.0","lymphoma":"401.3","Myeloma":"125.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051293"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA051293":"AB_2681424"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.40e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.89e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"}},{"Gene":"LARGE1","Gene synonym":["KIAA0609","LARGE"],"Ensembl":"ENSG00000133424","Gene description":"LARGE xylosyl- and glucuronyltransferase 1","Uniprot":["O95461"],"Chromosome":"22","Position":"33162226-33922841","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Multifunctional enzyme","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"414.0","Inhibitory neurons":"345.8","Oligodendrocyte precursor cells":"249.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"18.3","basal ganglia":"23.4","cerebral cortex":"33.2","hippocampal formation":"45.4","white matter":"16.4"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"}},{"Gene":"LARP4B","Gene synonym":["KIAA0217","LARP5"],"Ensembl":"ENSG00000107929","Gene description":"La ribonucleoprotein 4B","Uniprot":["Q92615"],"Chromosome":"10","Position":"806914-931705","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Translation regulation"],"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036566","HPA042738"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036566":"AB_10673624","HPA042738":"AB_2678137"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"}},{"Gene":"LAS1L","Gene synonym":["FLJ12525","Las1"],"Ensembl":"ENSG00000001497","Gene description":"LAS1 like ribosome biogenesis factor","Uniprot":["Q9Y4W2"],"Chromosome":"X","Position":"65438549-65534810","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["rRNA processing"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"145.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044431","HPA061463"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centriolar satellite","Cytosol"],"Antibody RRID":{"HPA044431":"AB_10965695","HPA061463":"AB_2684530"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"}},{"Gene":"LAT","Gene synonym":["LAT1"],"Ensembl":"ENSG00000213658","Gene description":"Linker for activation of T cells","Uniprot":["O43561"],"Chromosome":"16","Position":"28984826-28990784","Protein class":["Disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Adaptive immunity","Immunity","Mast cell degranulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"117.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"19.5","NK-cells":"20.4","T-cells":"21.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"basophil":"307.7","gdT-cell":"303.4","MAIT T-cell":"212.5","memory CD4 T-cell":"295.1","memory CD8 T-cell":"307.2","naive CD4 T-cell":"276.0","naive CD8 T-cell":"266.9","NK-cell":"114.6","T-reg":"410.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"142","RNA blood lineage specific nTPM":{"granulocytes":"307.7","NK-cells":"114.6","T-cells":"410.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"93.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002223","HPA011157","CAB012978","CAB079960"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB002223":"AB_563852","CAB012978":null,"CAB079960":null,"HPA011157":"AB_1079237"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-4"}},{"Gene":"LAX1","Gene synonym":["FLJ20340","LAX"],"Ensembl":"ENSG00000122188","Gene description":"Lymphocyte transmembrane adaptor 1","Uniprot":["Q8IWV1"],"Chromosome":"1","Position":"203765177-203776372","Protein class":["Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"21.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"176.3","NK-cells":"31.2","Plasma cells":"63.0","T-cells":"31.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"B-cells":"7.5","NK-cells":"5.2","T-cells":"12.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Myeloma":"38.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Breast - Plasma cells","Colon - Mast cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002461","HPA003887","CAB025358"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB025358":null,"HPA002461":"AB_1079239","HPA003887":"AB_1079240"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"}},{"Gene":"LAYN","Gene synonym":["FLJ30977","FLJ31092"],"Ensembl":"ENSG00000204381","Gene description":"Layilin","Uniprot":["Q6UX15"],"Chromosome":"11","Position":"111540280-111561745","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"71.5","Basal respiratory cells":"41.1","Endothelial cells":"45.3","Peritubular cells":"57.2","Thymic epithelial cells":"39.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"22","RNA blood cell specific nTPM":{"myeloid DC":"11.2","T-reg":"13.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"123","RNA blood lineage specific nTPM":{"dendritic cells":"11.2","T-cells":"13.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"73.4"},"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040087"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"340000","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA040087":"AB_10793927"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"}},{"Gene":"LBR","Gene synonym":["DHCR14B","TDRD18"],"Ensembl":"ENSG00000143815","Gene description":"Lamin B receptor","Uniprot":["Q14739"],"Chromosome":"1","Position":"225401502-225428925","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["DNA-binding","Oxidoreductase","Receptor"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"218.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Heart muscle - Endothelial cells","Prostate - Smooth muscle cells","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049840","HPA062236"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA049840":"AB_2680908","HPA062236":"AB_2684721"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.30e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"}},{"Gene":"LCK","Gene synonym":[],"Ensembl":"ENSG00000182866","Gene description":"LCK proto-oncogene, Src family tyrosine kinase","Uniprot":["P06239"],"Chromosome":"1","Position":"32251239-32286165","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"lymphoid tissue":"343.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"NK-cells":"191.1","T-cells":"253.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"gdT-cell":"1109.8","MAIT T-cell":"1034.8","memory CD4 T-cell":"1123.8","memory CD8 T-cell":"1201.7","naive CD4 T-cell":"1260.7","naive CD8 T-cell":"1168.7","NK-cell":"641.5","T-reg":"1682.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"NK-cells":"641.5","T-cells":"1682.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"91.2","lymphoma":"54.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - T-cells","Lung - T-cells","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003494","CAB003816"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB003816":"AB_562158","HPA003494":"AB_1852751"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.96e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.91e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.65e-5"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.60e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"}},{"Gene":"LCLAT1","Gene synonym":["AGPAT8","ALCAT1","FLJ37965","LYCAT"],"Ensembl":"ENSG00000172954","Gene description":"Lysocardiolipin acyltransferase 1","Uniprot":["Q6UWP7"],"Chromosome":"2","Position":"30447226-30644225","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Developmental protein","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"66.3","Inhibitory neurons":"84.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031880","HPA049217"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA031880":"AB_10610002","HPA049217":"AB_2680678"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.67e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.72e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"}},{"Gene":"LCT","Gene synonym":[],"Ensembl":"ENSG00000115850","Gene description":"Lactase","Uniprot":["P09848"],"Chromosome":"2","Position":"135787850-135837184","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase","Multifunctional enzyme"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"187","RNA tissue specific nTPM":{"intestine":"225.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"1.9","Breast myoepithelial cells":"3.6","Early spermatids":"1.4","Erythroid cells":"1.1","Proximal enterocytes":"2.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"15","RNA mouse brain regional specific nTPM":{"hippocampal formation":"15.7"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"LCTL","Gene synonym":["FLJ33279","KLG","KLPH"],"Ensembl":"ENSG00000188501","Gene description":"Lactase like","Uniprot":["Q6UWM7"],"Chromosome":"15","Position":"66547179-66565979","Protein class":["Cancer-related genes","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"2.8","Cone photoreceptor cells":"3.4","Early spermatids":"4.1","Late spermatids":"10.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"1.5","melanoma":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"6.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071640"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA071640":"AB_2686428"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"}},{"Gene":"LDHA","Gene synonym":[],"Ensembl":"ENSG00000134333","Gene description":"Lactate dehydrogenase A","Uniprot":["P00338"],"Chromosome":"11","Position":"18394560-18408425","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"1924.6","Extravillous trophoblasts":"2272.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015336","CAB069404"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB015336":"AB_2134947","CAB069404":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.26e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.27e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.09e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.69e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"}},{"Gene":"LDLR","Gene synonym":["LDLCQ2"],"Ensembl":"ENSG00000130164","Gene description":"Low density lipoprotein receptor","Uniprot":["P01130"],"Chromosome":"19","Position":"11089462-11133820","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Endocytosis","Host-virus interaction","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"112.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"272.7","Alveolar cells type 2":"420.9","Suprabasal keratinocytes":"288.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"46.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"46.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Neutrophils","Heart muscle - Endothelial cells","Testis - Leydig cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009647","HPA013159"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA009647":"AB_1079243","HPA013159":"AB_1852775"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.60e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.43e-4"}},{"Gene":"LDLRAD3","Gene synonym":["LRAD3"],"Ensembl":"ENSG00000179241","Gene description":"Low density lipoprotein receptor class A domain containing 3","Uniprot":["Q86YD5"],"Chromosome":"11","Position":"35943981-36232136","Protein class":["Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"89.5","Excitatory neurons":"67.8","Microglial cells":"102.2","Oligodendrocyte precursor cells":"295.5","Oligodendrocytes":"203.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"4.8","non-classical monocyte":"6.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038251"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA038251":"AB_10675790"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.24e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.34e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.05e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.14e-5"}},{"Gene":"LDLRAD4","Gene synonym":["C18orf1"],"Ensembl":"ENSG00000168675","Gene description":"Low density lipoprotein receptor class A domain containing 4","Uniprot":["O15165"],"Chromosome":"18","Position":"13217498-13652755","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Signal transduction inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"48.2","lymphoid tissue":"49.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"461.9","Excitatory neurons":"334.6","Inhibitory neurons":"302.0","Late spermatids":"276.1","Microglial cells":"417.8","Oligodendrocyte precursor cells":"305.2","Oligodendrocytes":"268.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"31.8","lymphoma":"19.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047633","HPA065246"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA047633":null,"HPA065246":"AB_2685444"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.58e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"}},{"Gene":"LEMD1","Gene synonym":["CT50","LEMP-1"],"Ensembl":"ENSG00000186007","Gene description":"LEM domain containing 1","Uniprot":["Q68G75"],"Chromosome":"1","Position":"205381378-205455954","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"epididymis":"14.8","testis":"55.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"4356.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"10.6"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"2.6","medulla oblongata":"2.4","midbrain":"1.2","pons":"2.8","thalamus":"2.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"17.8"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Prostate - Urothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"cerebellum":"3.9"},"Antibody":["HPA045425"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA045425":"AB_10960538"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.26e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"}},{"Gene":"LEMD2","Gene synonym":["dJ482C21.1","LEM2","NET25"],"Ensembl":"ENSG00000161904","Gene description":"LEM domain nuclear envelope protein 2","Uniprot":["Q8NC56"],"Chromosome":"6","Position":"33771202-33789130","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017340"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA017340":"AB_2296925"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"}},{"Gene":"LEMD3","Gene synonym":["MAN1"],"Ensembl":"ENSG00000174106","Gene description":"LEM domain containing 3","Uniprot":["Q9Y2U8"],"Chromosome":"12","Position":"65169583-65248355","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025078","HPA076986"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA025078":"AB_10601908","HPA076986":"AB_2686821"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.30e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"}},{"Gene":"LENG8","Gene synonym":["KIAA1932","MGC40108","pp13842"],"Ensembl":"ENSG00000167615","Gene description":"Leukocyte receptor cluster member 8","Uniprot":["Q96PV6"],"Chromosome":"19","Position":"54448887-54462016","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"626.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042004","HPA061571"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA042004":"AB_10794642","HPA061571":"AB_2684562"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.59e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.30e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.73e-6"}},{"Gene":"LEPR","Gene synonym":["CD295","OBR"],"Ensembl":"ENSG00000116678","Gene description":"Leptin receptor","Uniprot":["P48357"],"Chromosome":"1","Position":"65420652-65641559","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"liver":"130.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"99.0","Endothelial cells":"72.8","Fibroblasts":"91.7","Hepatocytes":"138.9","Microglial cells":"125.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"liver cancer":"13.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"4.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"4.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Endothelial cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030899"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":8240000,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030899":"AB_10610003"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"}},{"Gene":"LEPROT","Gene synonym":["FLJ90360","OB-RGRP","OBRGRP","VPS55"],"Ensembl":"ENSG00000213625","Gene description":"Leptin receptor overlapping transcript","Uniprot":["O15243"],"Chromosome":"1","Position":"65420587-65436007","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"455.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069444"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA069444":"AB_2686137"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"}},{"Gene":"LEPROTL1","Gene synonym":["my047","Vps55"],"Ensembl":"ENSG00000104660","Gene description":"Leptin receptor overlapping transcript like 1","Uniprot":["O95214"],"Chromosome":"8","Position":"30095408-30177208","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"T-cells":"372.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047911"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047911":"AB_2680206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.04e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"}},{"Gene":"LETM1","Gene synonym":["SLC55A1"],"Ensembl":"ENSG00000168924","Gene description":"Leucine zipper and EF-hand containing transmembrane protein 1","Uniprot":["O95202"],"Chromosome":"4","Position":"1811479-1856156","Protein class":["Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"102.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011029","HPA011100"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA011029":"AB_1852804","HPA011100":"AB_1852802"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.79e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.77e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.90e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"}},{"Gene":"LETM2","Gene synonym":["FLJ25409","SLC55A2"],"Ensembl":"ENSG00000165046","Gene description":"Leucine zipper and EF-hand containing transmembrane protein 2","Uniprot":["Q2VYF4"],"Chromosome":"8","Position":"38386207-38409527","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"testis":"23.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"92.8","Late spermatids":"54.7","Spermatocytes":"47.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"21.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"21.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"cerebellum":"24.0"},"Antibody":["HPA025032"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA025032":"AB_1852808"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"}},{"Gene":"LETMD1","Gene synonym":["HCCR","HCCR-1","HCCR-2","HCCR1","HCCR2","SLC55A3"],"Ensembl":"ENSG00000050426","Gene description":"LETM1 domain containing 1","Uniprot":["Q6P1Q0"],"Chromosome":"12","Position":"51047962-51060424","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074361"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Nucleoli"],"Antibody RRID":{"HPA074361":"AB_2686682"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.16e-4"}},{"Gene":"LGALSL","Gene synonym":["GRP","HSPC159"],"Ensembl":"ENSG00000119862","Gene description":"Galectin like","Uniprot":["Q3ZCW2"],"Chromosome":"2","Position":"64453969-64461381","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"90.6","skin 1":"93.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"89.3","Cone photoreceptor cells":"101.7","Muller glia cells":"90.0","Rod photoreceptor cells":"118.7","Suprabasal keratinocytes":"185.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1.5","neutrophil":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046079"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4100000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA046079":"AB_10967075"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.16e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"}},{"Gene":"LGR4","Gene synonym":["GPR48"],"Ensembl":"ENSG00000205213","Gene description":"Leucine rich repeat containing G protein-coupled receptor 4","Uniprot":["Q9BXB1"],"Chromosome":"11","Position":"27365961-27472790","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms","Differentiation","Immunity","Innate immunity","Spermatogenesis","Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"198.0","Glandular and luminal cells":"136.4","Syncytiotrophoblasts":"122.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Skin - Outer root sheath cells","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030267","HPA054350"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"HPA030267":"AB_10610004","HPA054350":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.00e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"}},{"Gene":"LGR5","Gene synonym":["FEX","GPR49","GPR67","HG38"],"Ensembl":"ENSG00000139292","Gene description":"Leucine rich repeat containing G protein-coupled receptor 5","Uniprot":["O75473"],"Chromosome":"12","Position":"71439798-71586310","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"19.2","fallopian tube":"16.8","placenta":"19.0","skeletal muscle":"22.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"52.4","Endometrial ciliated cells":"31.5","Glandular and luminal cells":"75.0","Oligodendrocyte precursor cells":"43.3","Oligodendrocytes":"99.1","Syncytiotrophoblasts":"25.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"26.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"26.4"},"RNA tissue cell type enrichment":["Breast - Fibroblasts"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"8","RNA mouse brain regional specific nTPM":{"olfactory bulb":"34.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012530"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA012530":"AB_1849329"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.09e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-3"}},{"Gene":"LGR6","Gene synonym":["FLJ14471"],"Ensembl":"ENSG00000133067","Gene description":"Leucine rich repeat containing G protein-coupled receptor 6","Uniprot":["Q9HBX8"],"Chromosome":"1","Position":"202193799-202319781","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"17.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"5.6","Basal squamous epithelial cells":"10.5","Breast myoepithelial cells":"8.3","Cardiomyocytes":"9.4","NK-cells":"10.2","Smooth muscle cells":"6.6","Spermatocytes":"5.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"17.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"gdT-cell":"15.4","memory CD8 T-cell":"9.1","naive CD8 T-cell":"4.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"37","RNA blood lineage specific nTPM":{"T-cells":"15.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"6.7","colorectal cancer":"8.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Skeletal muscle - Smooth muscle cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"olfactory bulb":"24.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008556"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA008556":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.35e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"}},{"Gene":"LHCGR","Gene synonym":["HHG","LCGR","LGR2","LHR","ULG5"],"Ensembl":"ENSG00000138039","Gene description":"Luteinizing hormone\/choriogonadotropin receptor","Uniprot":["P22888"],"Chromosome":"2","Position":"48686774-48755730","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.2","ovary":"2.1","testis":"2.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Theca cells":"93.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009814","HPA073668"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"CAB009814":"AB_2135467","HPA073668":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"LHFPL1","Gene synonym":[],"Ensembl":"ENSG00000182508","Gene description":"LHFPL tetraspan subfamily member 1","Uniprot":["Q86WI0"],"Chromosome":"X","Position":"112630648-112680054","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"11.2","salivary gland":"2.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"4.4","Basal prostatic cells":"1.5","Inhibitory neurons":"1.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"testis cancer":"3.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"olfactory bulb":"3.3"},"Antibody":["HPA003029"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003029":"AB_1079248"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"}},{"Gene":"LHFPL2","Gene synonym":["KIAA0206"],"Ensembl":"ENSG00000145685","Gene description":"LHFPL tetraspan subfamily member 2","Uniprot":["Q6ZUX7"],"Chromosome":"5","Position":"78485215-78770021","Protein class":["Predicted membrane proteins"],"Biological process":["Fertilization"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"116.8","Microglial cells":"204.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"7.9","plasmacytoid DC":"6.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"6.3","granulocytes":"7.9","monocytes":"3.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042402","HPA076743"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear bodies","Vesicles"],"Antibody RRID":{"HPA042402":"AB_10794276","HPA076743":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.73e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.45e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"}},{"Gene":"LHFPL3","Gene synonym":["LHFPL4"],"Ensembl":"ENSG00000187416","Gene description":"LHFPL tetraspan subfamily member 3","Uniprot":["Q86UP9"],"Chromosome":"7","Position":"104328700-104907232","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"30.5","retina":"23.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"19","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"4587.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"glioma":"27.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"1.1","skin cancer":"1.2"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069691"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA069691":"AB_2686171"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"}},{"Gene":"LHFPL4","Gene synonym":["GARLH4"],"Ensembl":"ENSG00000156959","Gene description":"LHFPL tetraspan subfamily member 4","Uniprot":["Q7Z7J7"],"Chromosome":"3","Position":"9498361-9553822","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"15.5","pituitary gland":"12.2","retina":"9.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"39.0","Excitatory neurons":"59.1","Horizontal cells":"22.4","Inhibitory neurons":"65.6","Oligodendrocyte precursor cells":"32.7","Rod photoreceptor cells":"16.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"6.8","testis cancer":"5.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Gallbladder cancer":"12.5","Neuroblastoma":"12.5"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041421"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA041421":"AB_10796673"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"}},{"Gene":"LHFPL5","Gene synonym":["DFNB67","dJ510O8.8","MGC33835","Tmhs"],"Ensembl":"ENSG00000197753","Gene description":"LHFPL tetraspan subfamily member 5","Uniprot":["Q8TAF8"],"Chromosome":"6","Position":"35797206-35845397","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"18.8","epididymis":"12.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"10.9","Mucus glandular cells":"15.8","Rod photoreceptor cells":"29.8","Squamous epithelial cells":"14.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"3.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029421","HPA055110"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029421":null,"HPA055110":"AB_2682697"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"}},{"Gene":"LHFPL6","Gene synonym":["LHFP","MGC22429"],"Ensembl":"ENSG00000183722","Gene description":"LHFPL tetraspan subfamily member 6","Uniprot":["Q9Y693"],"Chromosome":"13","Position":"39209116-39603528","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"181.3","Astrocytes":"210.0","Excitatory neurons":"196.3","Extravillous trophoblasts":"188.4","Fibroblasts":"246.5","Leydig cells":"303.1","Microglial cells":"420.5","Oligodendrocyte precursor cells":"271.0","Smooth muscle cells":"276.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"myeloid DC":"6.2","plasmacytoid DC":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"dendritic cells":"6.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Liver - Hepatic stellate cells","Pancreas - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058975"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA058975":"AB_2683866"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.30e-4"}},{"Gene":"LIFR","Gene synonym":["CD118"],"Ensembl":"ENSG00000113594","Gene description":"LIF receptor subunit alpha","Uniprot":["P42702"],"Chromosome":"5","Position":"38474668-38608354","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"342.0","Astrocytes":"365.0","Endothelial cells":"339.3","Oligodendrocytes":"260.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.92e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.40e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"}},{"Gene":"LILRA1","Gene synonym":["CD85i","LIR-6","LIR6"],"Ensembl":"ENSG00000104974","Gene description":"Leukocyte immunoglobulin like receptor A1","Uniprot":["O75019"],"Chromosome":"19","Position":"54593582-54602381","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"11.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"19.5","Kupffer cells":"55.3","Macrophages":"31.3","monocytes":"116.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"126.8","non-classical monocyte":"169.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"169.2"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Kupffer cells","Lung - Neutrophil_2","Prostate - Macrophages","Stomach - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"94000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"}},{"Gene":"LILRA2","Gene synonym":["CD85h","ILT1","LIR-7","LIR7"],"Ensembl":"ENSG00000239998","Gene description":"Leukocyte immunoglobulin like receptor A2","Uniprot":["Q8N149"],"Chromosome":"19","Position":"54572920-54590287","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"15.5","lymphoid tissue":"57.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hofbauer cells":"52.7","Kupffer cells":"69.8","Macrophages":"41.6","monocytes":"102.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"31.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"31.6","monocytes":"11.6"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"2.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Colon - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Neutrophil_2","Pancreas - Macrophages","Prostate - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"}},{"Gene":"LILRA4","Gene synonym":["CD85g","ILT7"],"Ensembl":"ENSG00000239961","Gene description":"Leukocyte immunoglobulin like receptor A4","Uniprot":["P59901"],"Chromosome":"19","Position":"54333185-54339162","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"lymphoid tissue":"10.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"dendritic cells":"605.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"21","RNA blood cell specific nTPM":{"plasmacytoid DC":"176.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"dendritic cells":"176.1"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049418"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049418":"AB_2680756"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"}},{"Gene":"LILRA5","Gene synonym":["CD85","CD85f","ILT11","LILRB7","LIR9"],"Ensembl":"ENSG00000187116","Gene description":"Leukocyte immunoglobulin like receptor A5","Uniprot":["A6NI73"],"Chromosome":"19","Position":"54307070-54313166","Protein class":["CD markers","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"43.5","lymphoid tissue":"76.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"monocytes":"458.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"128.6","intermediate monocyte":"252.7","neutrophil":"137.2","non-classical monocyte":"311.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"137.2","monocytes":"311.7"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Heart muscle - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2","Skeletal muscle - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"670000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.78e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"}},{"Gene":"LILRA6","Gene synonym":["CD85b","ILT8","LILRB6"],"Ensembl":"ENSG00000244482","Gene description":"Leukocyte immunoglobulin like receptor A6","Uniprot":["Q6PI73"],"Chromosome":"19","Position":"54236592-54242791","Protein class":["Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"9.0","lymphoid tissue":"16.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"20.2","Kupffer cells":"87.1","Macrophages":"29.8","monocytes":"21.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"3.4","intermediate monocyte":"3.9","neutrophil":"8.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"granulocytes":"8.2","monocytes":"3.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Kidney - Macrophages","Lung - Neutrophil_2","Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026985"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA026985":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"}},{"Gene":"LILRB1","Gene synonym":["CD85","CD85j","ILT2","LIR-1","LIR1","MIR-7","PIR-B","PIRB"],"Ensembl":"ENSG00000104972","Gene description":"Leukocyte immunoglobulin like receptor B1","Uniprot":[],"Chromosome":"19","Position":"54617158-54637528","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"36.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"27.5","dendritic cells":"59.3","Hofbauer cells":"29.7","Kupffer cells":"49.5","Macrophages":"65.4","Microglial cells":"30.1","monocytes":"169.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"intermediate monocyte":"39.3","non-classical monocyte":"63.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"monocytes":"63.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"17","RNA cell line specific nTPM":{"Leukemia":"1.5","lymphoma":"1.8","Myeloma":"1.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Liver - Kupffer cells","Prostate - T-cells","Stomach - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.08e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"}},{"Gene":"LILRB2","Gene synonym":["CD85d","ILT4","LIR-2","LIR2","MIR-10","MIR10"],"Ensembl":"ENSG00000131042","Gene description":"Leukocyte immunoglobulin like receptor B2","Uniprot":["Q8N423"],"Chromosome":"19","Position":"54273812-54281184","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"35.0","lung":"15.0","lymphoid tissue":"51.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"117.4","Hofbauer cells":"64.1","Kupffer cells":"246.4","Langerhans cells":"84.7","Macrophages":"119.5","monocytes":"561.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"61.6","intermediate monocyte":"132.3","neutrophil":"62.9","non-classical monocyte":"153.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"62.9","monocytes":"153.4"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Kidney - Macrophages","Lung - Neutrophil_2","Stomach - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"65000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.45e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"}},{"Gene":"LILRB3","Gene synonym":["CD85a","HL9","ILT5","LIR-3","LIR3","PIR-B","PIRB"],"Ensembl":"ENSG00000204577","Gene description":"Leukocyte immunoglobulin like receptor B3","Uniprot":["O75022"],"Chromosome":"19","Position":"54216278-54223506","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"27.0","lymphoid tissue":"49.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hofbauer cells":"88.5","Kupffer cells":"118.4","Macrophages":"81.0","monocytes":"139.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"44.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"44.8","monocytes":"15.4"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Liver - Neutrophils","Lung - Neutrophil_2","Skin - Macrophages","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026985"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA026985":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"}},{"Gene":"LILRB4","Gene synonym":["CD85k","HM18","ILT3","LIR-5","LIR5"],"Ensembl":"ENSG00000186818","Gene description":"Leukocyte immunoglobulin like receptor B4","Uniprot":["Q8NHJ6"],"Chromosome":"19","Position":"54643889-54670359","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"13.7","lymphoid tissue":"18.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"188.5","Hofbauer cells":"139.3","Kupffer cells":"84.7","Macrophages":"91.4","monocytes":"45.8","Plasma cells":"49.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"37.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"44","RNA blood lineage specific nTPM":{"dendritic cells":"37.3","monocytes":"10.8"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Myeloma":"25.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Pancreas - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052807"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"11000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052807":"AB_2681958"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"}},{"Gene":"LILRB5","Gene synonym":["CD85c","LIR-8","LIR8"],"Ensembl":"ENSG00000105609","Gene description":"Leukocyte immunoglobulin like receptor B5","Uniprot":["O75023"],"Chromosome":"19","Position":"54249421-54257301","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"17.9","lymphoid tissue":"49.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"54.2","Kupffer cells":"16.7","Macrophages":"75.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Skeletal muscle - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012069"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000000","Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012069":"AB_1852873"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"}},{"Gene":"LIM2","Gene synonym":["MP17","MP19"],"Ensembl":"ENSG00000105370","Gene description":"Lens intrinsic membrane protein 2","Uniprot":["P55344"],"Chromosome":"19","Position":"51379909-51387974","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"NK-cells":"11.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"40","RNA cancer specific FPKM":{"testis cancer":"18.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"gdT-cell":"11.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"T-cells":"11.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Sarcoma":"1.6"},"RNA tissue cell type enrichment":["Lung - NK-cells (Lung)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"LIME1","Gene synonym":["dJ583P15.4","FLJ20406","LIME"],"Ensembl":"ENSG00000203896","Gene description":"Lck interacting transmembrane adaptor 1","Uniprot":["Q9H400"],"Chromosome":"20","Position":"63736283-63739103","Protein class":["Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"liver":"242.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Plasma cells":"155.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"314.8","MAIT T-cell":"285.2","memory CD4 T-cell":"437.6","memory CD8 T-cell":"412.5","naive CD4 T-cell":"289.4","naive CD8 T-cell":"319.4","plasmacytoid DC":"749.3","T-reg":"689.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"749.3","T-cells":"689.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Myeloma":"160.3"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015363"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015363":"AB_629890"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.04e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.92e-6"}},{"Gene":"LIMS2","Gene synonym":["PINCH-2","PINCH2"],"Ensembl":"ENSG00000072163","Gene description":"LIM zinc finger domain containing 2","Uniprot":["Q7Z4I7"],"Chromosome":"2","Position":"127638381-127681786","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"510.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"116.3","Alveolar cells type 1":"57.2","Cardiomyocytes":"56.3","Endothelial cells":"109.9","Granulosa cells":"132.4","Peritubular cells":"49.1","Smooth muscle cells":"66.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"22.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"B-cells":"22.5","T-cells":"10.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Prostate - Smooth muscle cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058340"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA058340":"AB_2683683"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.53e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"}},{"Gene":"LINC00634","Gene synonym":[],"Ensembl":"ENSG00000205704","Gene description":"Long intergenic non-protein coding RNA 634","Uniprot":[],"Chromosome":"22","Position":"41952174-41958933","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"33.2","choroid plexus":"10.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"5.1","Bipolar cells":"15.1","Early spermatids":"18.0","Excitatory neurons":"3.9","Horizontal cells":"4.5","Inhibitory neurons":"3.5","Late spermatids":"4.2","Oligodendrocyte precursor cells":"3.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"glioma":"5.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"3.1"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029815"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA029815":"AB_10601803"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"}},{"Gene":"LINC00672","Gene synonym":[],"Ensembl":"ENSG00000263874","Gene description":"Long intergenic non-protein coding RNA 672","Uniprot":[],"Chromosome":"17","Position":"38925168-38929384","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"40.6","Horizontal cells":"30.8","NK-cells":"31.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-4"}},{"Gene":"LINC02203","Gene synonym":[],"Ensembl":"ENSG00000280709","Gene description":"Long intergenic non-protein coding RNA 2203","Uniprot":[],"Chromosome":"15","Position":"21552795-21653276","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"47","RNA tissue specific nTPM":{"testis":"5.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"52","RNA single cell type specific nTPM":{"Early spermatids":"197.8","Late spermatids":"107.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057442"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA057442":"AB_2683442"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"LINC02210-CRHR1","Gene synonym":[],"Ensembl":"ENSG00000263715","Gene description":"LINC02210-CRHR1 readthrough","Uniprot":[],"Chromosome":"17","Position":"45620344-45835826","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"6.0","Excitatory neurons":"33.7","Inhibitory neurons":"22.5","Oligodendrocyte precursor cells":"8.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"1.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"LINGO1","Gene synonym":["FLJ14594","LERN1","LRRN6A"],"Ensembl":"ENSG00000169783","Gene description":"Leucine rich repeat and Ig domain containing 1","Uniprot":["Q96FE5"],"Chromosome":"15","Position":"77613027-77820900","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"56.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"262.5","Excitatory neurons":"267.8","Horizontal cells":"82.0","Inhibitory neurons":"215.4","Microglial cells":"163.3","Oligodendrocyte precursor cells":"230.6","Oligodendrocytes":"306.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"10","RNA brain regional specific nTPM":{"amygdala":"37.4","basal ganglia":"43.9","cerebral cortex":"56.1","hippocampal formation":"49.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"71.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074653"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"25000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA074653":"AB_2686706"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.23e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"}},{"Gene":"LINGO2","Gene synonym":["LERN3","LRRN6C"],"Ensembl":"ENSG00000174482","Gene description":"Leucine rich repeat and Ig domain containing 2","Uniprot":["Q7L985"],"Chromosome":"9","Position":"27948078-28670286","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"7.5","smooth muscle":"8.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Excitatory neurons":"1566.5","Inhibitory neurons":"960.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"NK-cell":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"NK-cells":"1.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"10.4"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells","Prostate - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016633","CAB025361"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025361":null,"HPA016633":"AB_1853362"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-4"}},{"Gene":"LINGO3","Gene synonym":["LERN2","LRRN6B"],"Ensembl":"ENSG00000220008","Gene description":"Leucine rich repeat and Ig domain containing 3","Uniprot":["P0C6S8"],"Chromosome":"19","Position":"2289784-2292024","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"34.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"40.9","Cone photoreceptor cells":"8.6","Horizontal cells":"6.4","Oligodendrocyte precursor cells":"16.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.4"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"34.1"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"1.3","eosinophil":"4.0","neutrophil":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"4.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"7.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"59.6"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"basal ganglia":"28.8","cerebellum":"19.6","hippocampal formation":"8.4"},"Antibody":["HPA043781","HPA059558"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA043781":"AB_2678668","HPA059558":"AB_2684062"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"}},{"Gene":"LINGO4","Gene synonym":["LRRN6D"],"Ensembl":"ENSG00000213171","Gene description":"Leucine rich repeat and Ig domain containing 4","Uniprot":["Q6UY18"],"Chromosome":"1","Position":"151800264-151805419","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"21.3","tongue":"5.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"1.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"cerebellum":"1.8","hypothalamus":"1.0","midbrain":"2.7","pons and medulla":"4.0","thalamus":"1.4"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"spinal cord":"19.7"},"Antibody":["HPA060781"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA060781":"AB_2684361"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"}},{"Gene":"LINS1","Gene synonym":["LINS","MRT27","WINS1"],"Ensembl":"ENSG00000140471","Gene description":"Lines homolog 1","Uniprot":["Q8NG48"],"Chromosome":"15","Position":"100559369-100603230","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038578","HPA038579"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA038578":"AB_2676095","HPA038579":"AB_10697393"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"}},{"Gene":"LITAF","Gene synonym":["FLJ38636","PIG7","SIMPLE","TP53I7"],"Ensembl":"ENSG00000189067","Gene description":"Lipopolysaccharide induced TNF factor","Uniprot":["Q99732"],"Chromosome":"16","Position":"11547722-11636381","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"861.3","NK-cells":"655.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"2578.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2578.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006960"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"HPA006960":"AB_1079254"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.25e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"}},{"Gene":"LITAFD","Gene synonym":[],"Ensembl":"ENSG00000283516","Gene description":"LITAF domain containing","Uniprot":["A0A1B0GVX0"],"Chromosome":"16","Position":"8881634-8885351","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"7.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"63","RNA single cell type specific nTPM":{"Early spermatids":"85.8","Late spermatids":"263.5"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"LMAN1","Gene synonym":["ERGIC-53","ERGIC53","F5F8D","FMFD1","gp58","MCFD1","MR60"],"Ensembl":"ENSG00000074695","Gene description":"Lectin, mannose binding 1","Uniprot":["P49257"],"Chromosome":"18","Position":"59327823-59359265","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"572.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002320","CAB037163"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"CAB037163":"AB_532237","HPA002320":"AB_1079256"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"}},{"Gene":"LMAN1L","Gene synonym":["ERGIC-53L","ERGL"],"Ensembl":"ENSG00000140506","Gene description":"Lectin, mannose binding 1 like","Uniprot":["Q9HAT1"],"Chromosome":"15","Position":"74812716-74825757","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"31.7","lymphoid tissue":"25.7","prostate":"60.9","salivary gland":"20.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Prostatic glandular cells":"5.6","Serous glandular cells":"3.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"45","RNA cancer specific FPKM":{"prostate cancer":"2.2"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"13.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"prostate cancer":"5.8"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"1.4"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"LMAN2","Gene synonym":["C5orf8","GP36B","VIP36"],"Ensembl":"ENSG00000169223","Gene description":"Lectin, mannose binding 2","Uniprot":["Q12907"],"Chromosome":"5","Position":"177331567-177351668","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"607.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003927","CAB033812"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"88000000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB033812":"AB_2136010","HPA003927":"AB_1079257"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.53e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"}},{"Gene":"LMAN2L","Gene synonym":["DKFZp564L2423","VIPL"],"Ensembl":"ENSG00000114988","Gene description":"Lectin, mannose binding 2 like","Uniprot":["Q9H0V9"],"Chromosome":"2","Position":"96705929-96740064","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026600"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026600":"AB_1852939"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"}},{"Gene":"LMBR1","Gene synonym":["ACHP","C7orf2","FLJ11665","ZRS"],"Ensembl":"ENSG00000105983","Gene description":"Limb development membrane protein 1","Uniprot":["Q8WVP7"],"Chromosome":"7","Position":"156668946-156893216","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"109.2","Inhibitory neurons":"125.8","Microglial cells":"96.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016592"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA016592":"AB_1852943"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.44e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"}},{"Gene":"LMBR1L","Gene synonym":["FLJ10494","KIAA1174"],"Ensembl":"ENSG00000139636","Gene description":"Limb development membrane protein 1 like","Uniprot":["Q6UX01"],"Chromosome":"12","Position":"49097136-49110900","Protein class":["Predicted membrane proteins"],"Biological process":["Endocytosis","Wnt signaling pathway"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Granulosa cells":"676.9","Late spermatids":"171.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.45e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-3"}},{"Gene":"LMBRD1","Gene synonym":["bA810I22.1","C6orf209","cblF","FLJ11240"],"Ensembl":"ENSG00000168216","Gene description":"LMBR1 domain containing 1","Uniprot":["Q9NUN5"],"Chromosome":"6","Position":"69672757-69867236","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Endocytosis","Gastrulation","Host-virus interaction","Transport"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"21.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016491","HPA019547"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA016491":null,"HPA019547":"AB_2281256"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.07e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"}},{"Gene":"LMBRD2","Gene synonym":["DKFZp434H2226"],"Ensembl":"ENSG00000164187","Gene description":"LMBR1 domain containing 2","Uniprot":["Q68DH5"],"Chromosome":"5","Position":"36098407-36151887","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"70.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"10.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"10.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012165"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA012165":"AB_2136131"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"}},{"Gene":"LMF1","Gene synonym":["C16orf26","FLJ12681","FLJ22302","JFP11","TMEM112","TMEM112A"],"Ensembl":"ENSG00000103227","Gene description":"Lipase maturation factor 1","Uniprot":["Q96S06"],"Chromosome":"16","Position":"853634-981318","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"65.5","Excitatory neurons":"89.6","Oligodendrocyte precursor cells":"208.4","Oligodendrocytes":"158.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.95e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-3"}},{"Gene":"LMF2","Gene synonym":["TMEM112B","TMEM153"],"Ensembl":"ENSG00000100258","Gene description":"Lipase maturation factor 2","Uniprot":["Q9BU23"],"Chromosome":"22","Position":"50502949-50507702","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"180.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"114.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062626"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA062626":"AB_2684812"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.47e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"}},{"Gene":"LMLN","Gene synonym":["Gp63","LMNL1","Msp"],"Ensembl":"ENSG00000185621","Gene description":"Leishmanolysin like peptidase","Uniprot":["Q96KR4"],"Chromosome":"3","Position":"197960200-198043720","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"33.8","Respiratory ciliated cells":"36.5","Spermatocytes":"33.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016481","HPA028844"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Focal adhesion sites","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Cytosol"],"Subcellular additional location":["Focal adhesion sites"],"Antibody RRID":{"HPA016481":"AB_1852955","HPA028844":"AB_10602347"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.77e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"}},{"Gene":"LMLN2","Gene synonym":[],"Ensembl":"ENSG00000283654","Gene description":"Leishmanolysin like peptidase 2","Uniprot":["A0A1B0GTW7"],"Chromosome":"14","Position":"23099062-23104989","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Heterotaxy"],"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Horizontal cells":"1.9"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"LMO3","Gene synonym":["DAT1","RBTNL2","Rhom-3"],"Ensembl":"ENSG00000048540","Gene description":"LIM domain only 3","Uniprot":["Q8TAP4"],"Chromosome":"12","Position":"16548372-16610594","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"93.7","intestine":"85.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 1":"309.7","Alveolar cells type 2":"236.7","Astrocytes":"284.7","Excitatory neurons":"222.8","Oligodendrocyte precursor cells":"107.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"32.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"17.4","ovarian cancer":"25.3"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.10e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"}},{"Gene":"LMO7","Gene synonym":["FBX20","FBXO20","KIAA0858"],"Ensembl":"ENSG00000136153","Gene description":"LIM domain 7","Uniprot":["Q8WWI1"],"Chromosome":"13","Position":"75620434-75859870","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"248.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"714.7","Cardiomyocytes":"520.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"177","RNA brain regional specific nTPM":{"amygdala":"12.6","basal ganglia":"19.9","cerebral cortex":"25.6","hippocampal formation":"14.9","white matter":"15.4"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"13.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Alveolar cells type 1","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"amygdala":"20.8","basal ganglia":"32.8","cerebral cortex":"26.6","hippocampal formation":"33.8"},"Antibody":["HPA020923","HPA050184"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8200","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA020923":"AB_1852963","HPA050184":"AB_2681045"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.12e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.51e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.75e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"}},{"Gene":"LMTK2","Gene synonym":["AATYK2","BREK","cprk","KIAA1079","KPI-2","KPI2","LMR2","PPP1R100"],"Ensembl":"ENSG00000164715","Gene description":"Lemur tyrosine kinase 2","Uniprot":["Q8IWU2"],"Chromosome":"7","Position":"98106862-98209638","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"113.3","Inhibitory neurons":"67.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"25.2"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010657","HPA041836"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Plasma membrane","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nuclear speckles","Centriolar satellite"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA010657":"AB_1079259","HPA041836":"AB_2677698"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.03e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"}},{"Gene":"LMTK3","Gene synonym":["KIAA1883","LMR3","PPP1R101","TYKLM3"],"Ensembl":"ENSG00000142235","Gene description":"Lemur tyrosine kinase 3","Uniprot":["Q96Q04"],"Chromosome":"19","Position":"48485271-48513935","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"44.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"30.6","Excitatory neurons":"36.4","Inhibitory neurons":"37.9","Ionocytes":"28.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040203","HPA077070"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA040203":"AB_10671690","HPA077070":"AB_2732330"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.18e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"}},{"Gene":"LNP1","Gene synonym":["NP3"],"Ensembl":"ENSG00000206535","Gene description":"Leukemia NUP98 fusion partner 1","Uniprot":["A1A4G5"],"Chromosome":"3","Position":"100401532-100456319","Protein class":["Disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"retina":"46.1","testis":"29.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"39.1","Cone photoreceptor cells":"129.2","Early spermatids":"164.9","Horizontal cells":"92.9","Late spermatids":"43.8","Spermatocytes":"76.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"1.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Liver - Hepatocytes","Lung - Fibroblast_1","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"amygdala":"6.8","cerebral cortex":"8.7","hippocampal formation":"7.3","olfactory bulb":"5.0"},"Antibody":["HPA047926"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nuclear speckles","Cytosol"],"Antibody RRID":{"HPA047926":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"}},{"Gene":"LNPEP","Gene synonym":["CAP","IRAP","P-LAP","PLAP"],"Ensembl":"ENSG00000113441","Gene description":"Leucyl and cystinyl aminopeptidase","Uniprot":["Q9UIQ6"],"Chromosome":"5","Position":"96935394-97037513","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Aminopeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"190.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043642"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9800000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043642":"AB_10964137"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"}},{"Gene":"LNPK","Gene synonym":["KIAA1715","LNP","LNP1","Ul"],"Ensembl":"ENSG00000144320","Gene description":"Lunapark, ER junction formation factor","Uniprot":["Q9C0E8"],"Chromosome":"2","Position":"175923882-176002839","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"178.9","Late spermatids":"148.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014205"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA014205":"AB_2234186"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"}},{"Gene":"LPAR1","Gene synonym":["edg-2","EDG2","Gpcr26","GPR26","LPA1","Mrec1.3","rec.1.3","vzg-1"],"Ensembl":"ENSG00000198121","Gene description":"Lysophosphatidic acid receptor 1","Uniprot":["Q92633"],"Chromosome":"9","Position":"110873263-111038458","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"358.4","choroid plexus":"122.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"591.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"9.1","eosinophil":"19.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"19.0","monocytes":"9.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Colon - Enteric glia cells","Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"}},{"Gene":"LPAR2","Gene synonym":["EDG-4","EDG4","LPA2"],"Ensembl":"ENSG00000064547","Gene description":"Lysophosphatidic acid receptor 2","Uniprot":["Q9HBW0"],"Chromosome":"19","Position":"19623655-19628930","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"76.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"35.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019616"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019616":"AB_1847988"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.43e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"}},{"Gene":"LPAR3","Gene synonym":["Edg-7","EDG7","HOFNH30","LP-A3","LPA3","RP4-678I3"],"Ensembl":"ENSG00000171517","Gene description":"Lysophosphatidic acid receptor 3","Uniprot":["Q9UBY5"],"Chromosome":"1","Position":"84811602-84893206","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"36.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"39.5","Endometrial ciliated cells":"31.6","Glandular and luminal cells":"51.3","Prostatic glandular cells":"59.8","Sertoli cells":"30.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"24.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"14.3","prostate cancer":"19.4"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013421"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA013421":"AB_1847990"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.31e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"}},{"Gene":"LPAR4","Gene synonym":["GPR23","LPA4","P2RY9","P2Y5-LIKE","P2Y9"],"Ensembl":"ENSG00000147145","Gene description":"Lysophosphatidic acid receptor 4","Uniprot":["Q99677"],"Chromosome":"X","Position":"78747709-78757094","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.8","ovary":"3.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"9.8","Fibroblasts":"4.5","Leydig cells":"20.3","Mucus glandular cells":"11.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"basophil":"6.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"granulocytes":"6.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"2.6","testis cancer":"3.4"},"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046563","HPA054951","HPA055571"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear bodies","Vesicles"],"Antibody RRID":{"HPA046563":"AB_2732529","HPA054951":"AB_2682646","HPA055571":"AB_2682853"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-3"}},{"Gene":"LPAR5","Gene synonym":["GPR92","GPR93","KPG_010","LPA5"],"Ensembl":"ENSG00000184574","Gene description":"Lysophosphatidic acid receptor 5","Uniprot":["Q9H1C0"],"Chromosome":"12","Position":"6618835-6635960","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"20.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"25.3","Distal enterocytes":"23.2","Hofbauer cells":"34.4","Microglial cells":"32.8","Paneth cells":"23.8","Suprabasal keratinocytes":"20.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"18.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"83.8","T-cells":"66.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Mesothelial cells","Liver - Kupffer cells","Skeletal muscle - Macrophages","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013170"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013170":"AB_1849314"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.56e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"}},{"Gene":"LPAR6","Gene synonym":["P2RY5","P2Y5"],"Ensembl":"ENSG00000139679","Gene description":"Lysophosphatidic acid receptor 6","Uniprot":["P43657"],"Chromosome":"13","Position":"48389567-48444704","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"288.1","Basal squamous epithelial cells":"249.1","Early spermatids":"248.0","Langerhans cells":"916.6","Late spermatids":"364.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028934"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA028934":"AB_2672833"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.22e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.60e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"}},{"Gene":"LPCAT1","Gene synonym":["AGPAT10","AGPAT9","AYTL2","FLJ12443"],"Ensembl":"ENSG00000153395","Gene description":"Lysophosphatidylcholine acyltransferase 1","Uniprot":["Q8NF37"],"Chromosome":"5","Position":"1456480-1523962","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"57.3","lymphoid tissue":"38.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"516.0","Alveolar cells type 2":"557.7","Rod photoreceptor cells":"140.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"79.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012501","HPA022268"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Lipid droplets"],"Antibody RRID":{"HPA012501":"AB_1845224","HPA022268":"AB_1845225"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.11e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.67e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.88e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.90e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.64e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"}},{"Gene":"LPCAT2","Gene synonym":["AGPAT11","AYTL1","FLJ20481","LysoPAFAT"],"Ensembl":"ENSG00000087253","Gene description":"Lysophosphatidylcholine acyltransferase 2","Uniprot":["Q7L5N7"],"Chromosome":"16","Position":"55509072-55586666","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"88.3","thyroid gland":"86.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"129.2","Microglial cells":"218.9","monocytes":"97.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"23.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"151.4","eosinophil":"199.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"199.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Skeletal muscle - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007891","HPA008433"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Lipid droplets"],"Antibody RRID":{"HPA007891":"AB_1845223","HPA008433":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.43e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.03e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"}},{"Gene":"LPCAT3","Gene synonym":["C3F","MBOAT5","nessy","OACT5"],"Ensembl":"ENSG00000111684","Gene description":"Lysophosphatidylcholine acyltransferase 3","Uniprot":["Q6P1A2"],"Chromosome":"12","Position":"6976185-7018477","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"102.6","Proximal enterocytes":"123.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Alveolar cells type 2","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.89e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"LPCAT4","Gene synonym":["AGPAT7","AYTL3","FLJ10257","LPAAT-eta","LPEAT2"],"Ensembl":"ENSG00000176454","Gene description":"Lysophosphatidylcholine acyltransferase 4","Uniprot":["Q643R3"],"Chromosome":"15","Position":"34358633-34367196","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"90.3","Gastric mucus-secreting cells":"124.6","Paneth cells":"98.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057321"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057321":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.99e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-3"}},{"Gene":"LPGAT1","Gene synonym":["FAM34A","FAM34A1","KIAA0205","NET8"],"Ensembl":"ENSG00000123684","Gene description":"Lysophosphatidylglycerol acyltransferase 1","Uniprot":["Q92604"],"Chromosome":"1","Position":"211743457-211830763","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"420.2","Oligodendrocytes":"447.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"16.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"}},{"Gene":"LPIN1","Gene synonym":["KIAA0188"],"Ensembl":"ENSG00000134324","Gene description":"Lipin 1","Uniprot":["Q14693"],"Chromosome":"2","Position":"11677595-11827409","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Transcription","Transcription regulation"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"193.5","tongue":"137.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Late spermatids":"1682.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024591","HPA038021"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA024591":null,"HPA038021":"AB_10669514"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-1"}},{"Gene":"LRAT","Gene synonym":["LCA14"],"Ensembl":"ENSG00000121207","Gene description":"Lecithin retinol acyltransferase","Uniprot":["O95237"],"Chromosome":"4","Position":"154626945-154753120","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sensory transduction","Vision"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"20.8","Granulosa cells":"107.7","Schwann cells":"49.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Lung - Alveolar cells type 2","Skin - Outer root sheath cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070726"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Endoplasmic reticulum","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA070726":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-6"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"}},{"Gene":"LRBA","Gene synonym":["BGL","CDC4L","LAB300","LBA"],"Ensembl":"ENSG00000198589","Gene description":"LPS responsive beige-like anchor protein","Uniprot":["P50851"],"Chromosome":"4","Position":"150264435-151015727","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"210.6","Inhibitory neurons":"188.3","Oligodendrocyte precursor cells":"229.6","Oligodendrocytes":"205.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skin - Keratinocyte (other)","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019366","HPA023597"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"340000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA019366":"AB_2138441","HPA023597":"AB_1853256"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.22e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"}},{"Gene":"LRCH1","Gene synonym":["CHDC1","KIAA1016"],"Ensembl":"ENSG00000136141","Gene description":"Leucine rich repeats and calponin homology domain containing 1","Uniprot":["Q9Y2L9"],"Chromosome":"13","Position":"46553168-46753040","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"87.9","Inhibitory neurons":"115.0","Microglial cells":"178.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"37.1"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021536"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Actin filaments","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA021536":"AB_1853258"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.24e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.67e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.75e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"}},{"Gene":"LRCH3","Gene synonym":["MGC4126"],"Ensembl":"ENSG00000186001","Gene description":"Leucine rich repeats and calponin homology domain containing 3","Uniprot":["Q96II8"],"Chromosome":"3","Position":"197791226-197888436","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"97.7","Oligodendrocytes":"131.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"38.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"38.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012380","HPA017299"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA012380":"AB_1853260","HPA017299":"AB_2669576"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.95e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"LRCH4","Gene synonym":["LRN","LRRN1"],"Ensembl":"ENSG00000077454","Gene description":"Leucine rich repeats and calponin homology domain containing 4","Uniprot":["O75427"],"Chromosome":"7","Position":"100574011-100586129","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"15.9","monocytes":"19.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037667","HPA037668"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Focal adhesion sites","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Nucleoplasm","Focal adhesion sites","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA037667":"AB_10671882","HPA037668":"AB_10672910"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-7"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"}},{"Gene":"LRFN1","Gene synonym":["KIAA1484","SALM2"],"Ensembl":"ENSG00000128011","Gene description":"Leucine rich repeat and fibronectin type III domain containing 1","Uniprot":["Q9P244"],"Chromosome":"19","Position":"39306566-39320863","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"30.0","Horizontal cells":"14.1","NK-cells":"7.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.31e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"}},{"Gene":"LRFN2","Gene synonym":["FIGLER2","KIAA1246","SALM1"],"Ensembl":"ENSG00000156564","Gene description":"Leucine rich repeat and fibronectin type III domain containing 2","Uniprot":["Q9ULH4"],"Chromosome":"6","Position":"40391591-40587364","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"6.4","retina":"3.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"23.4","Cone photoreceptor cells":"93.1","Excitatory neurons":"109.9","Inhibitory neurons":"61.1","Oligodendrocyte precursor cells":"47.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"6.4","cerebral cortex":"5.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"2.2","Neuroblastoma":"3.8"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076660"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA076660":"AB_2686812"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-4"}},{"Gene":"LRFN3","Gene synonym":["FIGLER1","MGC2656","SALM4"],"Ensembl":"ENSG00000126243","Gene description":"Leucine rich repeat and fibronectin type III domain containing 3","Uniprot":["Q9BTN0"],"Chromosome":"19","Position":"35935358-35946624","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048923"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048923":"AB_2680558"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.46e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"}},{"Gene":"LRFN4","Gene synonym":["FIGLER6","MGC3103","SALM3."],"Ensembl":"ENSG00000173621","Gene description":"Leucine rich repeat and fibronectin type III domain containing 4","Uniprot":["Q6PJG9"],"Chromosome":"11","Position":"66856647-66860475","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"22.4","Late spermatids":"28.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077570"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA077570":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"}},{"Gene":"LRFN5","Gene synonym":["C14orf146","FIGLER8","SALM5"],"Ensembl":"ENSG00000165379","Gene description":"Leucine rich repeat and fibronectin type III domain containing 5","Uniprot":["Q96NI6"],"Chromosome":"14","Position":"41606876-41904549","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"16.5","cervix":"10.1","parathyroid gland":"11.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Excitatory neurons":"862.2","Inhibitory neurons":"568.8","Oligodendrocyte precursor cells":"283.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"6.1"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Pancreas - Fibroblasts","Prostate - Fibroblasts","Skin - Fibroblast_2","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001177"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001177":"AB_1079274"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"}},{"Gene":"LRIT1","Gene synonym":["DKFZP434K091","FIGLER9","LRRC21","PAL"],"Ensembl":"ENSG00000148602","Gene description":"Leucine rich repeat, Ig-like and transmembrane domains 1","Uniprot":["Q9P2V4"],"Chromosome":"10","Position":"84231520-84241546","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"retina":"25.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"12.7","Cone photoreceptor cells":"10.3","Early spermatids":"34.9","Late spermatids":"38.5","Rod photoreceptor cells":"6.1","Spermatocytes":"10.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"LRIT2","Gene synonym":["AC022389.4","LRRC22"],"Ensembl":"ENSG00000204033","Gene description":"Leucine rich repeat, Ig-like and transmembrane domains 2","Uniprot":["A6NDA9"],"Chromosome":"10","Position":"84220571-84225544","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"20","RNA tissue specific nTPM":{"retina":"59.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"7.6","Cone photoreceptor cells":"5.2","Muller glia cells":"3.2","Rod photoreceptor cells":"21.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037788"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037788":"AB_10672393"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"LRIT3","Gene synonym":["CSNB1F","FIGLER4","FLJ44691"],"Ensembl":"ENSG00000183423","Gene description":"Leucine rich repeat, Ig-like and transmembrane domains 3","Uniprot":["Q3SXY7"],"Chromosome":"4","Position":"109848107-109872315","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Congenital stationary night blindness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"retina":"17.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"20.7","Muller glia cells":"8.2","Rod photoreceptor cells":"10.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013454"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Nucleoplasm","Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA013454":"AB_1853277"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"}},{"Gene":"LRP1","Gene synonym":["A2MR","APOER","APR","CD91","IGFBP-3R","IGFBP3R1","LRP","LRP1A"],"Ensembl":"ENSG00000123384","Gene description":"LDL receptor related protein 1","Uniprot":["Q07954"],"Chromosome":"12","Position":"57128483-57213361","Protein class":["Candidate cardiovascular disease genes","CD markers","Disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Endocytosis","Host-virus interaction"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"109.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"320.3","Leydig cells":"234.3","Peritubular cells":"183.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"18","RNA blood cell specific nTPM":{"classical monocyte":"4.3","intermediate monocyte":"2.2","myeloid DC":"1.6","non-classical monocyte":"2.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"dendritic cells":"1.6","monocytes":"4.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Liver - Hepatocytes","Lung - Fibroblast_2","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004182","CAB018621","HPA022903"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB018621":"AB_627893","HPA004182":"AB_2667163","HPA022903":"AB_10602426"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-5"}},{"Gene":"LRP10","Gene synonym":["DKFZP564C1940","LRP9","MGC8675","MST087","MSTP087"],"Ensembl":"ENSG00000197324","Gene description":"LDL receptor related protein 10","Uniprot":["Q7Z4F1"],"Chromosome":"14","Position":"22871740-22881713","Protein class":["Predicted membrane proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"59.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"59.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000932"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA000932":"AB_2281523"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.54e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.17e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"}},{"Gene":"LRP11","Gene synonym":["bA350J20.3","MANSC3"],"Ensembl":"ENSG00000120256","Gene description":"LDL receptor related protein 11","Uniprot":["Q86VZ4"],"Chromosome":"6","Position":"149818757-149864359","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"41.9","Inhibitory neurons":"43.3","Late spermatids":"49.6","Oligodendrocytes":"37.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017267"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA017267":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.31e-8"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.01e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"}},{"Gene":"LRP12","Gene synonym":["FLJ12929","ST7"],"Ensembl":"ENSG00000147650","Gene description":"LDL receptor related protein 12","Uniprot":["Q9Y561"],"Chromosome":"8","Position":"104489231-104589258","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"41.4","Excitatory neurons":"77.6","Inhibitory neurons":"52.3","Oligodendrocyte precursor cells":"61.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"47.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"granulocytes":"47.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017245"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Plasma membrane","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoli fibrillar center","Plasma membrane","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA017245":"AB_1857532"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.67e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"}},{"Gene":"LRP1B","Gene synonym":["LRP-DIT","LRPDIT"],"Ensembl":"ENSG00000168702","Gene description":"LDL receptor related protein 1B","Uniprot":["Q9NZR2"],"Chromosome":"2","Position":"140231423-142131016","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"22.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"2053.8","Excitatory neurons":"3694.4","Inhibitory neurons":"2847.8","Oligodendrocyte precursor cells":"5332.9","Oligodendrocytes":"1135.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"0.8","glioma":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"3.2"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069094","HPA074788"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA069094":"AB_2686082","HPA074788":"AB_2797273"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"LRP2","Gene synonym":["DBS","gp330"],"Ensembl":"ENSG00000081479","Gene description":"LDL receptor related protein 2","Uniprot":["P98164"],"Chromosome":"2","Position":"169127109-169362534","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Endocytosis","Hearing","Neurogenesis","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"70.5","kidney":"34.8","parathyroid gland":"44.7","retina":"29.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"85.7","Cytotrophoblasts":"60.9","Oligodendrocytes":"283.3","Proximal tubular cells":"264.2","Thymic epithelial cells":"89.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"29.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"6.3","testis cancer":"3.9"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Proximal tubular cells","Lung - Alveolar cells type 2","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005980","HPA064792"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"74000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Vesicles","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA005980":"AB_1079278","HPA064792":"AB_2685353"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"}},{"Gene":"LRP3","Gene synonym":["hLRp105","LRP-3"],"Ensembl":"ENSG00000130881","Gene description":"LDL receptor related protein 3","Uniprot":["O75074"],"Chromosome":"19","Position":"33177603-33208864","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"18.3","Bipolar cells":"12.1","Excitatory neurons":"19.2","Horizontal cells":"24.4","Inhibitory neurons":"19.0","Oligodendrocyte precursor cells":"14.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041658"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"HPA041658":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.12e-7"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"LRP4","Gene synonym":["CLSS","LRP-4","MEGF7","SOST2"],"Ensembl":"ENSG00000134569","Gene description":"LDL receptor related protein 4","Uniprot":["O75096"],"Chromosome":"11","Position":"46856717-46918642","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Endocytosis","Wnt signaling pathway"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"46.7","skin 1":"31.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"119.3","Oligodendrocyte precursor cells":"131.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"12.2","endometrial cancer":"8.6","glioma":"13.2","testis cancer":"15.6","thyroid cancer":"28.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate basal glandular cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011934","HPA012300"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm","Nucleoli","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA011934":"AB_1853286","HPA012300":"AB_1853288"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"}},{"Gene":"LRP5","Gene synonym":["BMND1","EVR1","EVR4","HBM","LR3","LRP7","OPPG","OPS","OPTA1","VBCH2"],"Ensembl":"ENSG00000162337","Gene description":"LDL receptor related protein 5","Uniprot":["O75197"],"Chromosome":"11","Position":"68312591-68449275","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis","Wnt signaling pathway"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Disease variant","Osteogenesis imperfecta","Osteopetrosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"129.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"82.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013001","HPA030505"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013001":"AB_2533267","HPA030505":"AB_2673505"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.55e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"}},{"Gene":"LRP6","Gene synonym":["ADCAD2"],"Ensembl":"ENSG00000070018","Gene description":"LDL receptor related protein 6","Uniprot":["O75581"],"Chromosome":"12","Position":"12116025-12267044","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis","Wnt signaling pathway"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"93.6","Oligodendrocyte precursor cells":"103.5","Oligodendrocytes":"91.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bile duct cancer":"54.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004490","HPA029925"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"390000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004490":"AB_627894","HPA029925":"AB_10601768"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"}},{"Gene":"LRP8","Gene synonym":["APOER2","HSZ75190","LRP-8","MCI1"],"Ensembl":"ENSG00000157193","Gene description":"LDL receptor related protein 8","Uniprot":["Q14114"],"Chromosome":"1","Position":"53242364-53328469","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Endocytosis","Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"24.0","thyroid gland":"41.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"40.8","Excitatory neurons":"35.4","Granulosa cells":"76.1","Horizontal cells":"51.3","Inhibitory neurons":"113.9","Microglial cells":"42.0","Sertoli cells":"35.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073031"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA073031":"AB_2732217"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.46e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.02e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"}},{"Gene":"LRRC15","Gene synonym":["LIB"],"Ensembl":"ENSG00000172061","Gene description":"Leucine rich repeat containing 15","Uniprot":["Q8TF66"],"Chromosome":"3","Position":"194355249-194369743","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"4.9","skin 1":"7.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endothelial cells":"4.1","Fibroblasts":"1.8","granulocytes":"1.6","Langerhans cells":"1.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"25.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"7.0","Brain cancer":"12.3"},"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035503"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1700000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA035503":"AB_10961253"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-3"}},{"Gene":"LRRC19","Gene synonym":["FLJ21302"],"Ensembl":"ENSG00000184434","Gene description":"Leucine rich repeat containing 19","Uniprot":["Q9H756"],"Chromosome":"9","Position":"26993136-27005672","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"36.2","kidney":"42.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"23.6","Distal enterocytes":"112.9","Enteroendocrine cells":"20.3","Intestinal goblet cells":"24.7","Paneth cells":"29.7","Proximal enterocytes":"70.2","Proximal tubular cells":"52.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"6.0","renal cancer":"5.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"colorectal cancer":"1.4"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Pancreas - Ductal cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.08e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"}},{"Gene":"LRRC24","Gene synonym":["LRRC14OS"],"Ensembl":"ENSG00000254402","Gene description":"Leucine rich repeat containing 24","Uniprot":["Q50LG9"],"Chromosome":"8","Position":"144522388-144527033","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"13.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"103.6","Cone photoreceptor cells":"108.6","Horizontal cells":"37.8","Late spermatids":"70.8","Rod photoreceptor cells":"76.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028171","HPA052250"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA028171":"AB_2672504","HPA052250":"AB_2681774"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"LRRC25","Gene synonym":["FLJ38116","MAPA"],"Ensembl":"ENSG00000175489","Gene description":"Leucine rich repeat containing 25","Uniprot":["Q8N386"],"Chromosome":"19","Position":"18391137-18397622","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"32.4","lymphoid tissue":"61.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Hofbauer cells":"69.1","Kupffer cells":"95.6","Macrophages":"85.0","monocytes":"209.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"classical monocyte":"320.6","eosinophil":"356.2","intermediate monocyte":"512.1","myeloid DC":"229.3","neutrophil":"573.0","non-classical monocyte":"706.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"60","RNA blood lineage specific nTPM":{"dendritic cells":"229.3","granulocytes":"573.0","monocytes":"706.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"2.1","lymphoma":"2.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Pancreas - Macrophages","Prostate - Macrophages","Skin - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029459"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"630000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Endoplasmic reticulum","Microtubules","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029459":"AB_10610005"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.93e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"}},{"Gene":"LRRC3","Gene synonym":["C21orf102","C21orf30","DKFZP434C128","LRRC3DN"],"Ensembl":"ENSG00000160233","Gene description":"Leucine rich repeat containing 3","Uniprot":["Q9BY71"],"Chromosome":"21","Position":"44455510-44462196","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"15.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"7.7","Hepatocytes":"24.2","Schwann cells":"6.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Liver - Hepatocytes","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017975"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017975":"AB_1853307"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-3"}},{"Gene":"LRRC32","Gene synonym":["D11S833E","GARP"],"Ensembl":"ENSG00000137507","Gene description":"Leucine rich repeat containing 32","Uniprot":["Q14392"],"Chromosome":"11","Position":"76657524-76670747","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Growth factor binding"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Adipocytes":"79.0","Endothelial cells":"138.4","Extravillous trophoblasts":"195.3","Smooth muscle cells":"57.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"2.2"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"T-cells":"2.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"9.7","Sarcoma":"9.5","testis cancer":"7.6"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055775","HPA058434"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"98000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA055775":"AB_2732600","HPA058434":"AB_2732622"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.93e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.64e-4"}},{"Gene":"LRRC37A","Gene synonym":["KIAA0563"],"Ensembl":"ENSG00000176681","Gene description":"Leucine rich repeat containing 37A","Uniprot":["A6NMS7"],"Chromosome":"17","Position":"46292733-46337794","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"11.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"53.8","Excitatory neurons":"85.7","Inhibitory neurons":"80.8","Microglial cells":"48.3","Oligodendrocyte precursor cells":"58.2","Oligodendrocytes":"45.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042121","HPA043056","HPA045090","HPA049080"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042121":"AB_2677858","HPA043056":"AB_2678294","HPA045090":"AB_2679211","HPA049080":"AB_2680624"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"}},{"Gene":"LRRC37A2","Gene synonym":["FLJ45049"],"Ensembl":"ENSG00000238083","Gene description":"Leucine rich repeat containing 37 member A2","Uniprot":["A6NM11"],"Chromosome":"17","Position":"46511511-46555650","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"testis":"6.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"32.9","Early spermatids":"46.4","Excitatory neurons":"55.1","Inhibitory neurons":"54.2","Microglial cells":"33.7","Oligodendrocyte precursor cells":"45.7","Oligodendrocytes":"43.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042121","HPA043056","HPA045090","HPA049080"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042121":"AB_2677858","HPA043056":"AB_2678294","HPA045090":"AB_2679211","HPA049080":"AB_2680624"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"}},{"Gene":"LRRC37A3","Gene synonym":["FLJ34306","KIAA0563"],"Ensembl":"ENSG00000176809","Gene description":"Leucine rich repeat containing 37 member A3","Uniprot":["O60309"],"Chromosome":"17","Position":"64854312-64919480","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"28.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"80.0","Excitatory neurons":"141.0","Inhibitory neurons":"157.5","Microglial cells":"73.9","Oligodendrocyte precursor cells":"105.4","Oligodendrocytes":"93.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042121","HPA043056","HPA045090"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042121":"AB_2677858","HPA043056":"AB_2678294","HPA045090":"AB_2679211"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.25e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-3"}},{"Gene":"LRRC37B","Gene synonym":[],"Ensembl":"ENSG00000185158","Gene description":"Leucine rich repeat containing 37B","Uniprot":["Q96QE4"],"Chromosome":"17","Position":"32007872-32053504","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"25.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"38.0","Early spermatids":"68.9","Excitatory neurons":"44.7","Inhibitory neurons":"32.6","Oligodendrocyte precursor cells":"38.0","Oligodendrocytes":"26.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"3.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1.5","NK-cells":"3.8","T-cells":"2.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015135"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015135":"AB_1853309"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"}},{"Gene":"LRRC38","Gene synonym":[],"Ensembl":"ENSG00000162494","Gene description":"Leucine rich repeat containing 38","Uniprot":["Q5VT99"],"Chromosome":"1","Position":"13474973-13514003","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"adrenal gland":"19.6","skeletal muscle":"44.5","tongue":"14.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"18.1","Horizontal cells":"5.1","Inhibitory neurons":"10.5","Skeletal myocytes":"20.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"head and neck cancer":"0.5","lung cancer":"0.8","testis cancer":"0.6","urothelial cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"6.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038778"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038778":"AB_10673294"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"LRRC3B","Gene synonym":["LRP15"],"Ensembl":"ENSG00000179796","Gene description":"Leucine rich repeat containing 3B","Uniprot":["Q96PB8"],"Chromosome":"3","Position":"26622806-26717537","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"28.0","choroid plexus":"8.7","skeletal muscle":"9.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"248.9","Early spermatids":"161.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"endometrial cancer":"0.7","glioma":"2.6","ovarian cancer":"1.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"2.6"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015568"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015568":"AB_1853282"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"}},{"Gene":"LRRC3C","Gene synonym":[],"Ensembl":"ENSG00000204913","Gene description":"Leucine rich repeat containing 3C","Uniprot":["A6NJW4"],"Chromosome":"17","Position":"39941474-39944734","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"11.1","Microglial cells":"3.6","Oligodendrocytes":"8.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071271"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA071271":"AB_2686378"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"LRRC4","Gene synonym":["NAG14"],"Ensembl":"ENSG00000128594","Gene description":"Leucine rich repeat containing 4","Uniprot":["Q9HBW1"],"Chromosome":"7","Position":"128027071-128032107","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"38.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"34.0","Inhibitory neurons":"22.1","Respiratory ciliated cells":"44.8","Rod photoreceptor cells":"47.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"38.5"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"13.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"granulocytes":"13.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"7.4"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051100"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA051100":"AB_2797241"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.19e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.98e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-3"}},{"Gene":"LRRC41","Gene synonym":["MUF1"],"Ensembl":"ENSG00000132128","Gene description":"Leucine rich repeat containing 41","Uniprot":["Q15345"],"Chromosome":"1","Position":"46261196-46303616","Protein class":["Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"147.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051941"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA051941":"AB_2681669"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.50e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.66e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"}},{"Gene":"LRRC4B","Gene synonym":["DKFZp761A179","HSM","LRIG4"],"Ensembl":"ENSG00000131409","Gene description":"Leucine rich repeat containing 4B","Uniprot":["Q9NT99"],"Chromosome":"19","Position":"50516892-50568435","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"61.2","cervix":"41.3","pituitary gland":"31.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"33.8","Bipolar cells":"16.2","Excitatory neurons":"31.7","Horizontal cells":"27.6","Inhibitory neurons":"37.5","Oligodendrocyte precursor cells":"28.4","Oligodendrocytes":"46.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"36.5","testis cancer":"9.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"15.6","Neuroblastoma":"24.8","Rhabdoid":"20.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Liver - Hepatic stellate cells","Skeletal muscle - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058986"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058986":"AB_2683871"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"}},{"Gene":"LRRC4C","Gene synonym":["KIAA1580","NGL-1"],"Ensembl":"ENSG00000148948","Gene description":"Leucine rich repeat containing 4C","Uniprot":["Q9HCJ2"],"Chromosome":"11","Position":"40114203-41459773","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"15.4","retina":"17.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"5264.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"9.2","Neuroblastoma":"2.4"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Fibroblasts","Liver - Hepatic stellate cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054800","HPA075816"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA054800":"AB_2682603","HPA075816":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"}},{"Gene":"LRRC52","Gene synonym":["FLJ25811"],"Ensembl":"ENSG00000162763","Gene description":"Leucine rich repeat containing 52","Uniprot":["Q8N7C0"],"Chromosome":"1","Position":"165544000-165563957","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"testis":"16.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"223.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-4"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-4"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"LRRC55","Gene synonym":["FLJ45686"],"Ensembl":"ENSG00000183908","Gene description":"Leucine rich repeat containing 55","Uniprot":["Q6ZSA7"],"Chromosome":"11","Position":"57181747-57191717","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"15.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"1.1","Endothelial cells":"1.6","Excitatory neurons":"1.9","Inhibitory neurons":"1.2","Skeletal myocytes":"2.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"9.0","ovarian cancer":"2.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Neuroblastoma":"3.1"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"105.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014053"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014053":"AB_2137630"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"}},{"Gene":"LRRC59","Gene synonym":["FLJ21675","PRO1855"],"Ensembl":"ENSG00000108829","Gene description":"Leucine rich repeat containing 59","Uniprot":["Q96AG4"],"Chromosome":"17","Position":"50375059-50397523","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"301.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030827","HPA030829"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"740000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA030827":"AB_10602704","HPA030829":"AB_10670045"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.60e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.00e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.12e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.87e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.19e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-5"}},{"Gene":"LRRC66","Gene synonym":[],"Ensembl":"ENSG00000188993","Gene description":"Leucine rich repeat containing 66","Uniprot":["Q68CR7"],"Chromosome":"4","Position":"51993702-52017620","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"22.5","skeletal muscle":"8.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"5.7","Distal enterocytes":"8.5","Excitatory neurons":"9.3","Inhibitory neurons":"7.2","Oligodendrocyte precursor cells":"7.7","Oligodendrocytes":"8.3","Paneth cells":"5.4","Proximal enterocytes":"19.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"2.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014549","HPA027839"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014549":"AB_1853062","HPA027839":"AB_10602705"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"}},{"Gene":"LRRC70","Gene synonym":["LOC100130733","SLRN"],"Ensembl":"ENSG00000186105","Gene description":"Leucine rich repeat containing 70","Uniprot":["Q7Z2Q7"],"Chromosome":"5","Position":"62578819-62581446","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"3.6","Endothelial cells":"2.6","granulocytes":"1.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013409"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013409":"AB_10601911"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"}},{"Gene":"LRRC8A","Gene synonym":["FLJ10337","KIAA1437","LRRC8","SWELL1"],"Ensembl":"ENSG00000136802","Gene description":"Leucine rich repeat containing 8 VRAC subunit A","Uniprot":["Q8IWT6"],"Chromosome":"9","Position":"128882133-128918039","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Ion transport","Spermatogenesis","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"132.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.83e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.27e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"}},{"Gene":"LRRC8B","Gene synonym":["KIAA0231","TA-LRRP"],"Ensembl":"ENSG00000197147","Gene description":"Leucine rich repeat containing 8 VRAC subunit B","Uniprot":["Q6P9F7"],"Chromosome":"1","Position":"89524829-89597861","Protein class":["Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"175.0","Inhibitory neurons":"192.6","Late spermatids":"86.6","Oligodendrocytes":"132.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017950"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017950":"AB_1853346"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.15e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.99e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"}},{"Gene":"LRRC8C","Gene synonym":["AD158"],"Ensembl":"ENSG00000171488","Gene description":"Leucine rich repeat containing 8 VRAC subunit C","Uniprot":["Q8TDW0"],"Chromosome":"1","Position":"89633072-89769903","Protein class":["Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"73.3","Excitatory neurons":"72.6","Inhibitory neurons":"96.9","Microglial cells":"180.6","Oligodendrocytes":"80.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"8.9","monocytes":"6.6","T-cells":"11.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Lung - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Stomach - Endothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029347"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA029347":"AB_10601544"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.75e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"}},{"Gene":"LRRC8D","Gene synonym":["FLJ10470","LRRC5"],"Ensembl":"ENSG00000171492","Gene description":"Leucine rich repeat containing 8 VRAC subunit D","Uniprot":["Q7L1W4"],"Chromosome":"1","Position":"89821014-89936611","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"80.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"79.0","Oligodendrocyte precursor cells":"140.6","Oligodendrocytes":"327.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"}},{"Gene":"LRRC8E","Gene synonym":["FLJ23420"],"Ensembl":"ENSG00000171017","Gene description":"Leucine rich repeat containing 8 VRAC subunit E","Uniprot":["Q6NSJ5"],"Chromosome":"19","Position":"7888505-7902021","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"12.3","Glandular and luminal cells":"12.7","Squamous epithelial cells":"11.8","Suprabasal keratinocytes":"15.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020466"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA020466":"AB_1853352"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"}},{"Gene":"LRRK2","Gene synonym":["DKFZp434H2111","FLJ45829","PARK8","RIPK7","ROCO2"],"Ensembl":"ENSG00000188906","Gene description":"Leucine rich repeat kinase 2","Uniprot":["Q5S007"],"Chromosome":"12","Position":"40196744-40369285","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Differentiation"],"Molecular function":["GTPase activation","Hydrolase","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lung":"52.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"727.9","monocytes":"143.5","Oligodendrocyte precursor cells":"246.0","Skeletal myocytes":"250.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"17.1","thyroid cancer":"22.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"neutrophil":"58.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"58.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"3.2","skin cancer":"3.2"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Liver - Hepatocytes","Lung - Alveolar cells type 2","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014293","CAB037160"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB037160":"AB_1840989","HPA014293":"AB_1853353"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.02e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-3"}},{"Gene":"LRRN1","Gene synonym":["FIGLER3"],"Ensembl":"ENSG00000175928","Gene description":"Leucine rich repeat neuronal 1","Uniprot":["Q6UXK5"],"Chromosome":"3","Position":"3799431-3849834","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"400.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"20.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"testis cancer":"104.4"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011071"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2400000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011071":"AB_1853355"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"}},{"Gene":"LRRN2","Gene synonym":["FIGLER7","GAC1","LRANK1","LRRN5"],"Ensembl":"ENSG00000170382","Gene description":"Leucine rich repeat neuronal 2","Uniprot":["O75325"],"Chromosome":"1","Position":"204617170-204685738","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"21.5","Excitatory neurons":"57.0","Horizontal cells":"21.1","Inhibitory neurons":"38.9","Oligodendrocyte precursor cells":"37.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"breast cancer":"6.1","endometrial cancer":"10.6","glioma":"16.8","ovarian cancer":"18.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"9.8"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029124"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA029124":"AB_10601545"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.59e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"}},{"Gene":"LRRN3","Gene synonym":["FIGLER5","FLJ11129","NLRR3"],"Ensembl":"ENSG00000173114","Gene description":"Leucine rich repeat neuronal 3","Uniprot":["Q9H3W5"],"Chromosome":"7","Position":"111091006-111125454","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"23.2","thyroid gland":"19.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"45.5","Cardiomyocytes":"30.9","Excitatory neurons":"80.0","Horizontal cells":"39.1","Inhibitory neurons":"45.3","Leydig cells":"58.5","Oligodendrocyte precursor cells":"58.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"17.5","thyroid cancer":"4.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"naive CD4 T-cell":"32.5","naive CD8 T-cell":"30.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"70","RNA blood lineage specific nTPM":{"T-cells":"32.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"52.4","Sarcoma":"13.3","testis cancer":"13.6"},"RNA tissue cell type enrichment":["Prostate - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043820","HPA046792"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043820":"AB_2678687","HPA046792":"AB_2679810"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"}},{"Gene":"LRRN4","Gene synonym":["C20orf75","dJ1056H1.1","NLRR4"],"Ensembl":"ENSG00000125872","Gene description":"Leucine rich repeat neuronal 4","Uniprot":["Q8WUT4"],"Chromosome":"20","Position":"6040546-6054060","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"8.3","lung":"9.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Alveolar cells type 1":"26.6","Thymic epithelial cells":"52.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"lung cancer":"4.6","ovarian cancer":"3.6","renal cancer":"11.7"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"2.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"40.7","Uterine cancer":"23.6"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Pancreas - Ductal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075974"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Nucleoli rim","Mitotic chromosome"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"73000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Nucleoli","Nucleoli rim","Mitotic chromosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA075974":"AB_2686770"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-3"}},{"Gene":"LRRN4CL","Gene synonym":[],"Ensembl":"ENSG00000177363","Gene description":"LRRN4 C-terminal like","Uniprot":["Q8ND94"],"Chromosome":"11","Position":"62686406-62689530","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"10.9","Fibroblasts":"51.3","Leydig cells":"27.5","Melanocytes":"26.1","Peritubular cells":"17.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"melanoma":"26.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"3.1"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Lung - Fibroblast_2","Pancreas - Fibroblasts","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Fibroblast_2","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050317"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA050317":"AB_2681084"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"}},{"Gene":"LRRTM1","Gene synonym":["FLJ32082"],"Ensembl":"ENSG00000162951","Gene description":"Leucine rich repeat transmembrane neuronal 1","Uniprot":["Q86UE6"],"Chromosome":"2","Position":"80288351-80304752","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"22.4","salivary gland":"12.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"7.0","Horizontal cells":"5.1","Inhibitory neurons":"12.8","Oligodendrocyte precursor cells":"10.1","Schwann cells":"34.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"endometrial cancer":"8.8","ovarian cancer":"16.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"7.0","Rhabdoid":"7.1"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046607","HPA062660"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA046607":null,"HPA062660":"AB_2684824"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-4"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-4"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"LRRTM2","Gene synonym":["KIAA0416"],"Ensembl":"ENSG00000146006","Gene description":"Leucine rich repeat transmembrane neuronal 2","Uniprot":["O43300"],"Chromosome":"5","Position":"138868921-138875368","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"13.7","retina":"4.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"12.1","Excitatory neurons":"23.4","Horizontal cells":"15.4","Inhibitory neurons":"23.8","Oligodendrocyte precursor cells":"27.0","Oligodendrocytes":"15.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"4.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"Neuroblastoma":"6.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"LRRTM3","Gene synonym":[],"Ensembl":"ENSG00000198739","Gene description":"Leucine rich repeat transmembrane neuronal 3","Uniprot":["Q86VH5"],"Chromosome":"10","Position":"66926036-67101551","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"2.6","brain":"4.8","ovary":"2.7","pituitary gland":"3.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"143.1","Excitatory neurons":"478.5","Inhibitory neurons":"563.8","Late spermatids":"180.8","Oligodendrocyte precursor cells":"576.2","Oligodendrocytes":"239.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"2.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"1.4"},"RNA tissue cell type enrichment":["Pancreas - Beta cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-1"}},{"Gene":"LRRTM4","Gene synonym":["FLJ12568"],"Ensembl":"ENSG00000176204","Gene description":"Leucine rich repeat transmembrane neuronal 4","Uniprot":["Q86VH4"],"Chromosome":"2","Position":"76747685-77593319","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"17.6","retina":"6.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Excitatory neurons":"3921.7","Inhibitory neurons":"2265.1","Oligodendrocyte precursor cells":"3599.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"}},{"Gene":"LRTM1","Gene synonym":["HT017"],"Ensembl":"ENSG00000144771","Gene description":"Leucine rich repeats and transmembrane domains 1","Uniprot":["Q9HBL6"],"Chromosome":"3","Position":"54918231-54967088","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"retina":"78.9","skeletal muscle":"25.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Bipolar cells":"324.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"1.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"}},{"Gene":"LRTM2","Gene synonym":[],"Ensembl":"ENSG00000166159","Gene description":"Leucine rich repeats and transmembrane domains 2","Uniprot":["Q8N967"],"Chromosome":"12","Position":"1820267-1836753","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"11.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"4.9","Excitatory neurons":"10.0","Horizontal cells":"21.8","Inhibitory neurons":"7.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Sarcoma":"4.5"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055094","HPA062745"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA055094":"AB_2682693","HPA062745":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"LSAMP","Gene synonym":["IGLON3","LAMP"],"Ensembl":"ENSG00000185565","Gene description":"Limbic system associated membrane protein","Uniprot":["Q13449"],"Chromosome":"3","Position":"115802363-117139389","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"73.9","retina":"41.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Astrocytes":"3275.7","Excitatory neurons":"986.3","Inhibitory neurons":"2090.3","Oligodendrocyte precursor cells":"2375.5","Oligodendrocytes":"881.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"13.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"17.4"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Liver - Hepatic stellate cells","Pancreas - Fibroblasts","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054051","HPA076122"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA054051":"AB_2682358","HPA076122":"AB_2686779"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"}},{"Gene":"LSM14B","Gene synonym":["bA11M20.3","C20orf40","FAM61B","FLJ25473","FT005","LSM13","RAP55B"],"Ensembl":"ENSG00000149657","Gene description":"LSM family member 14B","Uniprot":["Q9BX40"],"Chromosome":"20","Position":"62122461-62135374","Protein class":["Predicted intracellular proteins"],"Biological process":["Translation regulation"],"Molecular function":["Developmental protein","Ribonucleoprotein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Early spermatids":"152.7","Late spermatids":"587.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"2.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041274","HPA061189"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041274":"AB_2677388","HPA061189":"AB_2684448"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.61e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"}},{"Gene":"LSMEM1","Gene synonym":["C7orf53","FLJ39575"],"Ensembl":"ENSG00000181016","Gene description":"Leucine rich single-pass membrane protein 1","Uniprot":["Q8N8F7"],"Chromosome":"7","Position":"112480853-112491062","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"81.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"8.8","Excitatory neurons":"8.4","Inhibitory neurons":"7.5","Late spermatids":"27.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"3.2"},"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"amygdala":"1.4","basal ganglia":"1.0","cerebellum":"4.0","olfactory bulb":"3.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013753","HPA047988"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA013753":"AB_1848926","HPA047988":"AB_2680229"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"}},{"Gene":"LSMEM2","Gene synonym":["C3orf45","FLJ38608"],"Ensembl":"ENSG00000179564","Gene description":"Leucine rich single-pass membrane protein 2","Uniprot":["Q8N112"],"Chromosome":"3","Position":"50279087-50288114","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"23.9","skeletal muscle":"16.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Late spermatids":"283.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Enteric glia cells","Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079523"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA079523":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"}},{"Gene":"LSR","Gene synonym":["ILDR3","LISCH7"],"Ensembl":"ENSG00000105699","Gene description":"Lipolysis stimulated lipoprotein receptor","Uniprot":["Q86X29"],"Chromosome":"19","Position":"35248330-35267964","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"144.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"228.7","Ductal cells":"243.5","Exocrine glandular cells":"304.9","Syncytiotrophoblasts":"251.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 2","Prostate - Prostate basal glandular cells","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007270","HPA075309"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3500000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA007270":"AB_1079253","HPA075309":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"LST1","Gene synonym":["B144","D6S49E","LST-1"],"Ensembl":"ENSG00000204482","Gene description":"Leukocyte specific transcript 1","Uniprot":["O00453"],"Chromosome":"6","Position":"31586124-31588909","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell shape","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"bone marrow":"100.3","lung":"48.8","lymphoid tissue":"181.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"869.2","Kupffer cells":"1075.5","Langerhans cells":"1613.4","Macrophages":"784.1","monocytes":"3419.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"1746.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"Leukemia":"40.1"},"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Liver - Kupffer cells","Skeletal muscle - Macrophages","Skin - Langerhans cells","Stomach - Macrophages","Testis - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079451"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA079451":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.89e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.97e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.62e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"}},{"Gene":"LTB","Gene synonym":["p33","TNFC","TNFSF3"],"Ensembl":"ENSG00000227507","Gene description":"Lymphotoxin beta","Uniprot":["Q06643"],"Chromosome":"6","Position":"31580525-31582522","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"intestine":"66.7","lymphoid tissue":"229.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1093.3","dendritic cells":"320.2","Ductal cells":"270.7","Exocrine glandular cells":"811.3","T-cells":"571.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"28.4","lymphoma":"55.6"},"RNA tissue cell type enrichment":["Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Liver - T-cells","Prostate - T-cells","Skin - Langerhans cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048884"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA048884":"AB_2680543"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.36e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.74e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.31e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"}},{"Gene":"LTB4R","Gene synonym":["BLTR","CMKRL1","GPR16","LTB4R1","P2RY7","P2Y7"],"Ensembl":"ENSG00000213903","Gene description":"Leukotriene B4 receptor","Uniprot":["Q15722"],"Chromosome":"14","Position":"24311450-24318036","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"103.1","skin 1":"110.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"62.4","Kupffer cells":"60.4","Suprabasal keratinocytes":"95.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"18.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"100.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"100.3","monocytes":"38.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003873"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003873":"AB_1078288"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.44e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"}},{"Gene":"LTB4R2","Gene synonym":["BLT2","BLTR2","JULF2","NOP9"],"Ensembl":"ENSG00000213906","Gene description":"Leukotriene B4 receptor 2","Uniprot":["Q9NPC1"],"Chromosome":"14","Position":"24305734-24312053","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"37.7","skin 1":"46.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"15.7","Basal squamous epithelial cells":"15.9","Squamous epithelial cells":"16.2","Suprabasal keratinocytes":"25.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"4.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022689","HPA029680","HPA072921"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB022689":null,"HPA029680":"AB_10603013","HPA072921":"AB_2686557"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"}},{"Gene":"LTBR","Gene synonym":["D12S370","TNF-R-III","TNFCR","TNFR-RP","TNFR2-RP","TNFRSF3"],"Ensembl":"ENSG00000111321","Gene description":"Lymphotoxin beta receptor","Uniprot":["P36941"],"Chromosome":"12","Position":"6375045-6391571","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"71.3","intermediate monocyte":"66.3","myeloid DC":"49.8","neutrophil":"45.0","non-classical monocyte":"50.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"36","RNA blood lineage specific nTPM":{"dendritic cells":"49.8","granulocytes":"45.0","monocytes":"71.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026202","HPA061617"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB026202":null,"HPA061617":"AB_2732666"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.13e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"}},{"Gene":"LTC4S","Gene synonym":["MGC33147"],"Ensembl":"ENSG00000213316","Gene description":"Leukotriene C4 synthase","Uniprot":["Q16873"],"Chromosome":"5","Position":"179793980-179796647","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Leukotriene biosynthesis","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Lyase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"granulocytes":"559.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"20.2","eosinophil":"63.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"63.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Leukemia":"5.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044688"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Endoplasmic reticulum","Cytosol"],"Antibody RRID":{"HPA044688":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-1"}},{"Gene":"LTK","Gene synonym":["TYK1"],"Ensembl":"ENSG00000062524","Gene description":"Leukocyte receptor tyrosine kinase","Uniprot":["P29376"],"Chromosome":"15","Position":"41503637-41513887","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"13.2","lung":"15.1","salivary gland":"11.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"dendritic cells":"25.6","Distal enterocytes":"24.5","Gastric mucus-secreting cells":"16.1","Intestinal goblet cells":"9.4","Proximal enterocytes":"16.8","Respiratory ciliated cells":"7.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"MAIT T-cell":"5.7","plasmacytoid DC":"5.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"5.0","T-cells":"5.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Sinusoid Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059545"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059545":"AB_2684057"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"}},{"Gene":"LTN1","Gene synonym":["C21orf10","C21orf98","FLJ11053","KIAA0714","LISTERIN","RNF160","ZNF294"],"Ensembl":"ENSG00000198862","Gene description":"Listerin E3 ubiquitin protein ligase 1","Uniprot":["O94822"],"Chromosome":"21","Position":"28928144-28992956","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"150.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029143","CAB034164","HPA055604"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034164":"AB_2180094","HPA029143":"AB_10671360","HPA055604":"AB_2682859"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"}},{"Gene":"LY6D","Gene synonym":["E48"],"Ensembl":"ENSG00000167656","Gene description":"Lymphocyte antigen 6 family member D","Uniprot":["Q14210"],"Chromosome":"8","Position":"142784882-142786539","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"2074.3","skin 1":"850.4","vagina":"491.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal keratinocytes":"2241.6","Squamous epithelial cells":"2076.7","Suprabasal keratinocytes":"5267.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"cervical cancer":"409.8","head and neck cancer":"444.6","urothelial cancer":"242.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"368.3","head and neck cancer":"354.4"},"RNA tissue cell type enrichment":["Prostate - Urothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024755","HPA064317"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024755":"AB_1853410","HPA064317":"AB_2685244"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"LY6E","Gene synonym":["RIG-E","SCA-2","TSA-1"],"Ensembl":"ENSG00000160932","Gene description":"Lymphocyte antigen 6 family member E","Uniprot":["Q16553"],"Chromosome":"8","Position":"143017982-143023832","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"614.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"1532.4","Extravillous trophoblasts":"5485.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"753.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Urothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.74e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"}},{"Gene":"LY6G5C","Gene synonym":["C6orf20","G5c","NG33"],"Ensembl":"ENSG00000204428","Gene description":"Lymphocyte antigen 6 family member G5C","Uniprot":["Q5SRR4"],"Chromosome":"6","Position":"31676684-31684040","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"1.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"27.0","Spermatocytes":"17.1","Spermatogonia":"13.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"1.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038690"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038690":"AB_10673286"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.07e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"}},{"Gene":"LY6G6C","Gene synonym":["C6orf24","G6c","NG24"],"Ensembl":"ENSG00000204421","Gene description":"Lymphocyte antigen 6 family member G6C","Uniprot":["O95867"],"Chromosome":"6","Position":"31718648-31721746","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"skin 1":"511.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"151.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"20.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"6.3"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"}},{"Gene":"LY6G6D","Gene synonym":["C6orf23","G6D","Ly6-D","MEGT1","NG25"],"Ensembl":"ENSG00000244355","Gene description":"Lymphocyte antigen 6 family member G6D","Uniprot":["O95868"],"Chromosome":"6","Position":"31715356-31717804","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skin 1":"24.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"22","RNA cancer specific FPKM":{"colorectal cancer":"18.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"39","RNA cell line specific nTPM":{"colorectal cancer":"8.9"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"6.1"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054412"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054412":"AB_2682480"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"LY6G6E","Gene synonym":["C6orf22","G6e"],"Ensembl":"ENSG00000255552","Gene description":"Lymphocyte antigen 6 family member G6E","Uniprot":[],"Chromosome":"6","Position":"31711771-31714065","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1.4","skin 1":"1.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"colorectal cancer":"2.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056234"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":null,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA056234":"AB_2732601"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"LY6G6F","Gene synonym":["C6orf21","G6f","LY6G6D","NG32"],"Ensembl":"ENSG00000204424","Gene description":"Lymphocyte antigen 6 family member G6F","Uniprot":["Q5SQ64"],"Chromosome":"6","Position":"31706866-31710679","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"3.7","lymphoid tissue":"1.2","skin 1":"1.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"2.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"2.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.9"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008053"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"380000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008053":"AB_1840160"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"LY6G6F-LY6G6D","Gene synonym":["G6F-LY6G6D","MEGT-1","MEGT1"],"Ensembl":"ENSG00000250641","Gene description":"LY6G6F-LY6G6D readthrough","Uniprot":[],"Chromosome":"6","Position":"31706904-31717918","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"5.4","testis":"2.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Enteroendocrine cells":"18.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"23","RNA cancer specific FPKM":{"colorectal cancer":"9.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008053"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008053":"AB_1840160"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"LY6H","Gene synonym":["NMLY6"],"Ensembl":"ENSG00000176956","Gene description":"Lymphocyte antigen 6 family member H","Uniprot":["O94772"],"Chromosome":"8","Position":"143157914-143160711","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"114.7","choroid plexus":"35.0","pituitary gland":"55.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"22.3","Enteroendocrine cells":"18.4","Excitatory neurons":"24.4","Horizontal cells":"16.7","Inhibitory neurons":"46.6","Oligodendrocyte precursor cells":"21.7","Spermatogonia":"26.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"9.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"1.7","lung cancer":"1.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077218"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA077218":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-3"}},{"Gene":"LY6K","Gene synonym":["CT97","FLJ35226","HSJ001348"],"Ensembl":"ENSG00000160886","Gene description":"Lymphocyte antigen 6 family member K","Uniprot":["Q17RY6"],"Chromosome":"8","Position":"142700111-142705127","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"12.5","testis":"36.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"233.3","Spermatocytes":"449.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"11.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"neutrophil":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"granulocytes":"1.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"140.9"},"RNA tissue cell type enrichment":["Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017770","CAB075742","CAB075743","CAB079929"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB075742":"AB_2665748","CAB075743":"AB_2665749","CAB079929":null,"HPA017770":"AB_1853414"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.17e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"}},{"Gene":"LY6L","Gene synonym":[],"Ensembl":"ENSG00000261667","Gene description":"Lymphocyte antigen 6 family member L","Uniprot":["H3BQJ8"],"Chromosome":"8","Position":"143080457-143083001","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.1","kidney":"1.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"prostate cancer":"2.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"1.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"breast cancer":"1.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"LY75","Gene synonym":["CD205","CLEC13B","DEC-205"],"Ensembl":"ENSG00000054219","Gene description":"Lymphocyte antigen 75","Uniprot":["O60449"],"Chromosome":"2","Position":"159803355-159904756","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"78.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"31.7","Respiratory ciliated cells":"23.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"19.5"},"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001450","HPA049108","HPA054073"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB001450":"AB_563525","HPA049108":"AB_2680635","HPA054073":"AB_2682370"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.39e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.86e-4"}},{"Gene":"LY75-CD302","Gene synonym":[],"Ensembl":"ENSG00000248672","Gene description":"LY75-CD302 readthrough","Uniprot":[],"Chromosome":"2","Position":"159771851-159904710","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"2.4","intestine":"1.8","lymphoid tissue":"2.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"3.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049108"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049108":"AB_2680635"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-4"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"}},{"Gene":"LY9","Gene synonym":["CD229","hly9","mLY9","SLAMF3"],"Ensembl":"ENSG00000122224","Gene description":"Lymphocyte antigen 9","Uniprot":["Q9HBG7"],"Chromosome":"1","Position":"160796074-160828261","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Cell adhesion","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"11.5","intestine":"12.0","lymphoid tissue":"31.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"245.9","dendritic cells":"62.8","Langerhans cells":"37.8","Plasma cells":"72.1","T-cells":"45.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"gdT-cell":"112.9","MAIT T-cell":"113.5","memory B-cell":"56.1","memory CD4 T-cell":"97.6","memory CD8 T-cell":"109.8","naive B-cell":"52.8","naive CD4 T-cell":"109.6","naive CD8 T-cell":"112.3","plasmacytoid DC":"72.8","T-reg":"80.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"12.3","Myeloma":"38.9"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Colon - T-cells","Heart muscle - T-cells","Liver - T-cells","Pancreas - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050917"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"43000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA050917":"AB_2681272"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"}},{"Gene":"LYNX1","Gene synonym":["SLURP2"],"Ensembl":"ENSG00000180155","Gene description":"Ly6\/neurotoxin 1","Uniprot":["P0DP58"],"Chromosome":"8","Position":"142771197-142777810","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"136.8","heart muscle":"79.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"67.1","Excitatory neurons":"34.8","Hepatocytes":"26.0","Horizontal cells":"46.1","Inhibitory neurons":"21.6","Ionocytes":"21.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"intermediate monocyte":"6.6","non-classical monocyte":"17.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"monocytes":"17.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"310000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.82e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"}},{"Gene":"LYPD1","Gene synonym":["LYPDC1","MGC29643"],"Ensembl":"ENSG00000150551","Gene description":"LY6\/PLAUR domain containing 1","Uniprot":["Q8N2G4"],"Chromosome":"2","Position":"132643286-132671579","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"31.2","choroid plexus":"15.4","fallopian tube":"53.5","pituitary gland":"33.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"79.9","Exocrine glandular cells":"85.8","Oligodendrocyte precursor cells":"27.0","Serous glandular cells":"52.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"57.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"eosinophil":"3.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"granulocytes":"3.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"51.3"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068333"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA068333":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"}},{"Gene":"LYPD3","Gene synonym":["C4.4A"],"Ensembl":"ENSG00000124466","Gene description":"LY6\/PLAUR domain containing 3","Uniprot":["O95274"],"Chromosome":"19","Position":"43460787-43465608","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"1066.8","skin 1":"669.3","vagina":"487.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"573.0","Squamous epithelial cells":"889.9","Suprabasal keratinocytes":"2645.8","Syncytiotrophoblasts":"1067.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"158.5","head and neck cancer":"235.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"5.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"2.6","granulocytes":"2.1","T-cells":"5.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"69.6"},"RNA tissue cell type enrichment":["Prostate - Urothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041529","HPA041797","HPA077859"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7600000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Endoplasmic reticulum","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041529":"AB_2677534","HPA041797":"AB_2677679","HPA077859":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.86e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-3"}},{"Gene":"LYPD5","Gene synonym":["FLJ30469"],"Ensembl":"ENSG00000159871","Gene description":"LY6\/PLAUR domain containing 5","Uniprot":["Q6UWN5"],"Chromosome":"19","Position":"43785874-43827206","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"skin 1":"50.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"42.3","Late spermatids":"99.0","Syncytiotrophoblasts":"25.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"8.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"7.8"},"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Urothelial cells","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042511","HPA054670"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042511":"AB_10794279","HPA054670":"AB_2682567"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.84e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"}},{"Gene":"LYPD6","Gene synonym":["MGC52057"],"Ensembl":"ENSG00000187123","Gene description":"LY6\/PLAUR domain containing 6","Uniprot":["Q86Y78"],"Chromosome":"2","Position":"149329985-149474138","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"24.0","placenta":"15.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"39.5","Early spermatids":"37.7","Inhibitory neurons":"64.7","Late spermatids":"246.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Kidney - Ascending Loop of Henle cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042805"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042805":"AB_10794159"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.72e-4"}},{"Gene":"LYPD6B","Gene synonym":["CT116","LYPD7"],"Ensembl":"ENSG00000150556","Gene description":"LY6\/PLAUR domain containing 6B","Uniprot":["Q8NI32"],"Chromosome":"2","Position":"149038107-149215262","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"95.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"220.7","Gastric mucus-secreting cells":"79.3","Inhibitory neurons":"76.4","Late spermatids":"139.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"17.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"13.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"13.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Stomach - Gastric mucous cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049239"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049239":"AB_2680688"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"}},{"Gene":"LYPD8","Gene synonym":[],"Ensembl":"ENSG00000259823","Gene description":"LY6\/PLAUR domain containing 8","Uniprot":["Q6UX82"],"Chromosome":"1","Position":"248739415-248755759","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"intestine":"215.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal enterocytes":"278.9","Paneth cells":"1060.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"colorectal cancer":"15.2"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"10","RNA brain regional specific nTPM":{"amygdala":"1.1","basal ganglia":"1.6","cerebral cortex":"1.9","hippocampal formation":"1.1","white matter":"1.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"colorectal cancer":"1.3","lung cancer":"2.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"LYPLA1","Gene synonym":["APT-1","LPL1"],"Ensembl":"ENSG00000120992","Gene description":"Lysophospholipase 1","Uniprot":["O75608"],"Chromosome":"8","Position":"54046367-54102017","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"578.3","Late spermatids":"896.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050941","HPA063151"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"330000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA050941":"AB_2681284","HPA063151":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.34e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"}},{"Gene":"LYSMD3","Gene synonym":["FLJ13542"],"Ensembl":"ENSG00000176018","Gene description":"LysM domain containing 3","Uniprot":["Q7Z3D4"],"Chromosome":"5","Position":"90515611-90529584","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018024"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA018024":"AB_2138525"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.83e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"}},{"Gene":"LYSMD4","Gene synonym":["FLJ33008"],"Ensembl":"ENSG00000183060","Gene description":"LysM domain containing 4","Uniprot":["Q5XG99"],"Chromosome":"15","Position":"99715697-99733561","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029152","HPA059824"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA029152":"AB_10602033","HPA059824":"AB_2684135"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"}},{"Gene":"LYST","Gene synonym":["CHS","CHS1"],"Ensembl":"ENSG00000143669","Gene description":"Lysosomal trafficking regulator","Uniprot":["Q99698"],"Chromosome":"1","Position":"235661041-235883640","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Phagocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"31.3","retina":"27.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Melanocytes":"179.4","monocytes":"253.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"11.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"12.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"12.2","monocytes":"6.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"20.5"},"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053366","HPA055725"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane","Centriolar satellite"],"Antibody RRID":{"HPA053366":"AB_2682129","HPA055725":"AB_2682898"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.27e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"}},{"Gene":"LYVE1","Gene synonym":["LYVE-1","XLKD1"],"Ensembl":"ENSG00000133800","Gene description":"Lymphatic vessel endothelial hyaluronan receptor 1","Uniprot":["Q9Y5Y7"],"Chromosome":"11","Position":"10556966-10611689","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"126.4","placenta":"149.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endothelial cells":"119.5","Hofbauer cells":"720.1","Macrophages":"208.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"1.8"},"Antibody":["CAB025860","HPA042953"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025860":null,"HPA042953":"AB_2678238"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.07e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.98e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"}},{"Gene":"LYZL1","Gene synonym":["LYC2","MGC33408"],"Ensembl":"ENSG00000120563","Gene description":"Lysozyme like 1","Uniprot":["Q6UWQ5"],"Chromosome":"10","Position":"29289061-29318328","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"429","RNA tissue specific nTPM":{"testis":"51.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"54","RNA single cell type specific nTPM":{"Early spermatids":"685.9","Late spermatids":"227.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-3"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"LYZL2","Gene synonym":[],"Ensembl":"ENSG00000151033","Gene description":"Lysozyme like 2","Uniprot":["Q7Z4W2"],"Chromosome":"10","Position":"30611779-30629762","Protein class":["Enzymes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"712","RNA tissue specific nTPM":{"testis":"71.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"56","RNA single cell type specific nTPM":{"Early spermatids":"801.7","Late spermatids":"280.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-4"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"M6PR","Gene synonym":["CD-M6PR","CD-MPR"],"Ensembl":"ENSG00000003056","Gene description":"Mannose-6-phosphate receptor, cation dependent","Uniprot":["P20645"],"Chromosome":"12","Position":"8940361-8949761","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"240.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034464","HPA040445"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034464":"AB_2139108","HPA040445":"AB_2676989"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.89e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"}},{"Gene":"MACF1","Gene synonym":["ABP620","ACF7","FLJ45612","FLJ46776","KIAA0465","KIAA1251","MACF"],"Ensembl":"ENSG00000127603","Gene description":"Microtubule actin crosslinking factor 1","Uniprot":["Q9UPN3"],"Chromosome":"1","Position":"39081316-39487177","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Actin-binding"],"Disease involvement":["Disease variant","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1045.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013713","HPA068064","HPA068103"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"25000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane","Cell Junctions","Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA013713":"AB_10600821","HPA068064":"AB_2685946","HPA068103":"AB_2685953"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"}},{"Gene":"MACO1","Gene synonym":["FLJ10747","TMEM57"],"Ensembl":"ENSG00000204178","Gene description":"Macoilin 1","Uniprot":["Q8N5G2"],"Chromosome":"1","Position":"25430858-25500209","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"126.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019680"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019680":"AB_1858125"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-3"}},{"Gene":"MACROH2A2","Gene synonym":["H2AFY2"],"Ensembl":"ENSG00000099284","Gene description":"MacroH2A.2 histone","Uniprot":["Q9P0M6"],"Chromosome":"10","Position":"70052544-70112282","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chromatin regulator","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"84.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"12.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"12.6","monocytes":"5.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"113.8"},"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Skin - Keratinocyte (other)","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035865","HPA041189"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA035865":"AB_10672099","HPA041189":"AB_2677357"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"}},{"Gene":"MAD2L2","Gene synonym":["FANCV","MAD2B","POLZ2","REV7"],"Ensembl":"ENSG00000116670","Gene description":"Mitotic arrest deficient 2 like 2","Uniprot":["Q9UI95"],"Chromosome":"1","Position":"11674480-11691650","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","DNA damage","DNA repair","Mitosis","Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"140.7","Late spermatids":"516.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008110","HPA024176","HPA024612"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB008110":"AB_217976","HPA024176":"AB_2671467","HPA024612":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"}},{"Gene":"MADCAM1","Gene synonym":["MACAM1"],"Ensembl":"ENSG00000099866","Gene description":"Mucosal vascular addressin cell adhesion molecule 1","Uniprot":["Q13477"],"Chromosome":"19","Position":"489176-505343","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"11.7","lymphoid tissue":"13.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"6.9","Endothelial cells":"5.4","Horizontal cells":"5.8","Muller glia cells":"5.6","Rod photoreceptor cells":"5.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"1.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"neutrophil":"7.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"7.0"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB075699","HPA077998"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"80000000","Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB075699":null,"HPA077998":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"}},{"Gene":"MAEA","Gene synonym":["EMP","GID9","HLC-10","p44EMLP"],"Ensembl":"ENSG00000090316","Gene description":"Macrophage erythroblast attacher, E3 ubiquitin ligase","Uniprot":["Q7L5Y9"],"Chromosome":"4","Position":"1289887-1340147","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Erythrocyte maturation","Ubl conjugation pathway"],"Molecular function":["Actin-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036886","HPA058185"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA036886":null,"HPA058185":"AB_2683633"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.34e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.90e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"}},{"Gene":"MAF1","Gene synonym":["DKFZp586G1123"],"Ensembl":"ENSG00000179632","Gene description":"MAF1 homolog, negative regulator of RNA polymerase III","Uniprot":["Q9H063"],"Chromosome":"8","Position":"144104461-144107611","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024821","HPA058548","HPA072409"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA024821":"AB_2671696","HPA058548":"AB_2683751","HPA072409":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.09e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"}},{"Gene":"MAG","Gene synonym":["GMA","S-MAG","SIGLEC-4A","SIGLEC4A"],"Ensembl":"ENSG00000105695","Gene description":"Myelin associated glycoprotein","Uniprot":["P20916"],"Chromosome":"19","Position":"35292125-35313807","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"33","RNA tissue specific nTPM":{"brain":"731.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Oligodendrocytes":"252.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"20.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"plasmacytoid DC":"2.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"2.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"skin cancer":"7.9"},"RNA tissue cell type enrichment":["Kidney - Intercalated cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"white matter":"2742.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009345","HPA012499"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009345":"AB_670104","HPA012499":"AB_1854238"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"}},{"Gene":"MAGEA4","Gene synonym":["CT1.4","MAGE-41","MAGE-X2","MAGE4","MAGE4A","MAGE4B","MGC21336"],"Ensembl":"ENSG00000147381","Gene description":"MAGE family member A4","Uniprot":["P43358"],"Chromosome":"X","Position":"151912509-151925170","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Tumor antigen"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"23.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"20.9","Spermatocytes":"52.7","Spermatogonia":"199.8","Syncytiotrophoblasts":"36.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"19.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021942","CAB040535"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 47: Spermatogonia - Spermatogenesis","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB040535":null,"HPA021942":"AB_1853490"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-1"}},{"Gene":"MAGED1","Gene synonym":["DLXIN-1","NRAGE"],"Ensembl":"ENSG00000179222","Gene description":"MAGE family member D1","Uniprot":["Q9Y5V3"],"Chromosome":"X","Position":"51803007-51902354","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Ubl conjugation pathway"],"Molecular function":["Tumor antigen"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"333.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043645"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043645":"AB_2678597"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.25e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"}},{"Gene":"MAGED4","Gene synonym":["KIAA1859","MAGE-E1","MAGE1","MGC3210"],"Ensembl":"ENSG00000154545","Gene description":"MAGE family member D4","Uniprot":["Q96JG8"],"Chromosome":"X","Position":"52184823-52192268","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Tumor antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"4.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Melanocytes":"1.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"1.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003554"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003554":"AB_1853497"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MAGED4B","Gene synonym":[],"Ensembl":"ENSG00000187243","Gene description":"MAGE family member D4B","Uniprot":["Q96JG8"],"Chromosome":"X","Position":"52061827-52069248","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Tumor antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"47.2","pituitary gland":"22.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"5.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"B-cells":"5.1","dendritic cells":"3.8","T-cells":"3.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"43.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003554"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003554":"AB_1853497"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-6"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MAGEE1","Gene synonym":["DAMAGE","KIAA1587"],"Ensembl":"ENSG00000198934","Gene description":"MAGE family member E1","Uniprot":["Q9HCI5"],"Chromosome":"X","Position":"76427710-76431342","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Tumor antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"20.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"10.1","Cone photoreceptor cells":"8.6","Excitatory neurons":"12.0","Horizontal cells":"9.0","Inhibitory neurons":"11.9","Sertoli cells":"11.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003047"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA003047":"AB_1079298"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.95e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.86e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"}},{"Gene":"MAGEE2","Gene synonym":["HCA3"],"Ensembl":"ENSG00000186675","Gene description":"MAGE family member E2","Uniprot":["Q8TD90"],"Chromosome":"X","Position":"75782987-75785254","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Tumor antigen"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"2.3","Cone photoreceptor cells":"1.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"1.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030625"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030625":"AB_10601863"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"MAGEH1","Gene synonym":["APR1"],"Ensembl":"ENSG00000187601","Gene description":"MAGE family member H1","Uniprot":["Q9H213"],"Chromosome":"X","Position":"55452127-55453566","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Tumor antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"epididymis":"515.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Peritubular cells":"63.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"57.3"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Kidney - Fibroblasts","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011324","HPA011971"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":null,"Antibody RRID":{"HPA011324":"AB_1853499","HPA011971":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.37e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.60e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"}},{"Gene":"MAGT1","Gene synonym":["DKFZp564K142","IAP","MRX95","OST3B","SLC58A1"],"Ensembl":"ENSG00000102158","Gene description":"Magnesium transporter 1","Uniprot":["Q9H0U3"],"Chromosome":"X","Position":"77825747-77895593","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049851"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049851":"AB_2680913"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.30e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.98e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.55e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"}},{"Gene":"MAJIN","Gene synonym":["C11orf85"],"Ensembl":"ENSG00000168070","Gene description":"Membrane anchored junction protein","Uniprot":["Q3KP22"],"Chromosome":"11","Position":"64937517-64972108","Protein class":["Predicted intracellular proteins"],"Biological process":["Meiosis"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"testis":"22.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Spermatocytes":"181.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"1.0"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"2.6"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"1.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Gallbladder cancer":"12.0"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"}},{"Gene":"MAL","Gene synonym":["MVP17","VIP17"],"Ensembl":"ENSG00000172005","Gene description":"Mal, T cell differentiation protein","Uniprot":["P21145"],"Chromosome":"2","Position":"95025677-95053992","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"2817.9","vagina":"863.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"1696.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"101.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"memory CD4 T-cell":"217.6","naive CD4 T-cell":"293.3","naive CD8 T-cell":"138.1","T-reg":"233.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"38","RNA blood lineage specific nTPM":{"T-cells":"293.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"36.0","ovarian cancer":"67.9","Uterine cancer":"47.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Lung - Fibroblast_1","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065691"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA065691":"AB_2685533"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.18e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.96e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"}},{"Gene":"MAL2","Gene synonym":[],"Ensembl":"ENSG00000147676","Gene description":"Mal, T cell differentiation protein 2","Uniprot":["Q969L2"],"Chromosome":"8","Position":"119165034-119245673","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"259.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"395.3","Collecting duct cells":"338.7","Distal enterocytes":"308.7","Squamous epithelial cells":"323.3","Suprabasal keratinocytes":"588.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enterocytes","Lung - Alveolar cells type 2","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043831"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043831":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.57e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.44e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.98e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.39e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-3"}},{"Gene":"MALL","Gene synonym":["BENE"],"Ensembl":"ENSG00000144063","Gene description":"Mal, T cell differentiation protein like","Uniprot":["Q13021"],"Chromosome":"2","Position":"110083870-110116022","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"368.5","intestine":"235.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"187.3","Alveolar cells type 2":"230.3","Distal enterocytes":"557.1","Ductal cells":"264.8","Paneth cells":"210.1","Proximal enterocytes":"780.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"8.4","neutrophil":"2.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"8.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Lung - Alveolar cells type 2","Skin - Keratinocyte (other)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051410"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051410":"AB_2681474"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-3"}},{"Gene":"MALRD1","Gene synonym":["bA265G8.2","C10orf112","Diet1"],"Ensembl":"ENSG00000204740","Gene description":"MAM and LDL receptor class A domain containing 1","Uniprot":["Q5VYJ5"],"Chromosome":"10","Position":"19048801-19790401","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"intestine":"31.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"36.7","Oligodendrocyte precursor cells":"73.2","Proximal enterocytes":"62.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"0.9","stomach cancer":"1.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.1","Myeloma":"1.9"},"RNA tissue cell type enrichment":["Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035732","HPA038106","HPA046848"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA035732":"AB_2674756","HPA038106":"AB_2675836","HPA046848":"AB_2679837"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-4"}},{"Gene":"MAMDC4","Gene synonym":["AEGP","DKFZp434M1411","EDTB"],"Ensembl":"ENSG00000177943","Gene description":"MAM domain containing 4","Uniprot":["Q6UXC1"],"Chromosome":"9","Position":"136850943-136860799","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"30.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"27.3","Hepatocytes":"20.6","Intestinal goblet cells":"23.3","Proximal enterocytes":"23.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"1.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026377","HPA059977"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB026377":null,"HPA059977":"AB_2684186"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.88e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"}},{"Gene":"MAN1A1","Gene synonym":[],"Ensembl":"ENSG00000111885","Gene description":"Mannosidase alpha class 1A member 1","Uniprot":["P33908"],"Chromosome":"6","Position":"119177205-119349761","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"154.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"246.8","Excitatory neurons":"162.5","Hepatocytes":"222.0","Plasma cells":"162.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"118.2"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037058","HPA053198","HPA063561"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"460000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB037058":"AB_477183","HPA053198":"AB_2682078","HPA063561":"AB_2685042"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"}},{"Gene":"MAN1A2","Gene synonym":["MAN1B"],"Ensembl":"ENSG00000198162","Gene description":"Mannosidase alpha class 1A member 2","Uniprot":["O60476"],"Chromosome":"1","Position":"117367449-117528872","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"282.1","Syncytiotrophoblasts":"419.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034559","HPA057364"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA034559":"AB_10671229","HPA057364":"AB_2683419"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.08e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"}},{"Gene":"MAN1B1","Gene synonym":["ERManI","MANA-ER","MRT15"],"Ensembl":"ENSG00000177239","Gene description":"Mannosidase alpha class 1B member 1","Uniprot":["Q9UKM7"],"Chromosome":"9","Position":"137086985-137109183","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051516"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"940000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA051516":"AB_2681518"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.45e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"}},{"Gene":"MAN1C1","Gene synonym":["HMIC"],"Ensembl":"ENSG00000117643","Gene description":"Mannosidase alpha class 1C member 1","Uniprot":["Q9NR34"],"Chromosome":"1","Position":"25616791-25786206","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"77.5","Excitatory neurons":"71.8","Hepatocytes":"53.1","Inhibitory neurons":"64.5","Syncytiotrophoblasts":"54.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"4.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"4.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048352"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA048352":"AB_2680368"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.55e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.79e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"}},{"Gene":"MAN2A1","Gene synonym":["GOLIM7","MANA2"],"Ensembl":"ENSG00000112893","Gene description":"Mannosidase alpha class 2A member 1","Uniprot":["Q16706"],"Chromosome":"5","Position":"109689927-109869625","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"107.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Oligodendrocytes":"1999.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022377","HPA026896"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB022377":null,"HPA026896":"AB_1853512"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-3"}},{"Gene":"MAN2A2","Gene synonym":["HsT19662","MANA2X"],"Ensembl":"ENSG00000196547","Gene description":"Mannosidase alpha class 2A member 2","Uniprot":["P49641"],"Chromosome":"15","Position":"90902218-90922584","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"87.4","Rod photoreceptor cells":"71.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"8.8","neutrophil":"7.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077930"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"43000000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Cytoplasmic bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA077930":"AB_2732363"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.95e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"}},{"Gene":"MAN2B1","Gene synonym":["LAMAN","MANB"],"Ensembl":"ENSG00000104774","Gene description":"Mannosidase alpha class 2B member 1","Uniprot":["O00754"],"Chromosome":"19","Position":"12646511-12666742","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"26.6","dendritic cells":"39.8","Langerhans cells":"29.3","Macrophages":"25.5","Plasma cells":"64.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"201.8","intermediate monocyte":"178.8","myeloid DC":"158.8","non-classical monocyte":"138.4","plasmacytoid DC":"187.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"187.5","monocytes":"201.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Lung - Macrophages","Prostate - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041530","HPA053404"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3200000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 34: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041530":"AB_10795639","HPA053404":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"}},{"Gene":"MANBA","Gene synonym":[],"Ensembl":"ENSG00000109323","Gene description":"Mannosidase beta","Uniprot":["O00462"],"Chromosome":"4","Position":"102630770-102760994","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Macrophages":"69.3","Microglial cells":"108.5","monocytes":"76.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"16.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"5.3","granulocytes":"16.6","monocytes":"9.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053478"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA053478":"AB_2682165"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.56e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.74e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"}},{"Gene":"MANBAL","Gene synonym":["dJ1141E15.2"],"Ensembl":"ENSG00000101363","Gene description":"Mannosidase beta like","Uniprot":["Q9NQG1"],"Chromosome":"20","Position":"37289638-37317260","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"151.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052348"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA052348":"AB_2681795"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.07e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"}},{"Gene":"MANEA","Gene synonym":["FLJ12838","mandaselin"],"Ensembl":"ENSG00000172469","Gene description":"Mannosidase endo-alpha","Uniprot":["Q5SRI9"],"Chromosome":"6","Position":"95577535-95609452","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"46.7","Plasma cells":"100.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011046","HPA011069"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA011046":"AB_1079303","HPA011069":"AB_1079304"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.04e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"}},{"Gene":"MANSC1","Gene synonym":["FLJ10298","LOH12CR3"],"Ensembl":"ENSG00000111261","Gene description":"MANSC domain containing 1","Uniprot":["Q9H8J5"],"Chromosome":"12","Position":"12326056-12350242","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"70.0"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"neutrophil":"98.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"39","RNA blood lineage specific nTPM":{"granulocytes":"98.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bile duct cancer":"130.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007955","HPA007956"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA007955":"AB_1079306","HPA007956":"AB_1079305"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.30e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"}},{"Gene":"MANSC4","Gene synonym":[],"Ensembl":"ENSG00000205693","Gene description":"MANSC domain containing 4","Uniprot":["A6NHS7"],"Chromosome":"12","Position":"27762427-27780236","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"1.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"4.7","Horizontal cells":"2.6","Rod photoreceptor cells":"1.2","Sertoli cells":"2.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Podocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039454","HPA039682"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039454":"AB_2676515","HPA039682":"AB_10805483"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"}},{"Gene":"MAOA","Gene synonym":[],"Ensembl":"ENSG00000189221","Gene description":"Monoamine oxidase A","Uniprot":["P21397"],"Chromosome":"X","Position":"43654907-43746824","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Catecholamine metabolism","Neurotransmitter degradation"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"230.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"294.4","Proximal enterocytes":"829.2","Proximal tubular cells":"522.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"42.6","prostate cancer":"53.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009437","HPA054807","HPA059299"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB009437":"AB_2137260","HPA054807":"AB_2682607","HPA059299":"AB_2683970"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"}},{"Gene":"MAOB","Gene synonym":[],"Ensembl":"ENSG00000069535","Gene description":"Monoamine oxidase B","Uniprot":["P27338"],"Chromosome":"X","Position":"43766610-43882450","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"317.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"131.8","granulocytes":"193.1","Hepatocytes":"213.2","Peritubular cells":"96.6","Proximal enterocytes":"182.4","Proximal tubular cells":"143.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"24.2","liver cancer":"31.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Lung - Fibroblast_1","Prostate - Smooth muscle cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002328","CAB037200"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037200":"AB_1841012","HPA002328":"AB_1854062"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"}},{"Gene":"MAP1B","Gene synonym":["MAP5","PPP1R102"],"Ensembl":"ENSG00000131711","Gene description":"Microtubule associated protein 1B","Uniprot":["P46821"],"Chromosome":"5","Position":"72107234-72209565","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"431.3","retina":"154.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"440.2","Cone photoreceptor cells":"1113.3","Excitatory neurons":"563.9","Horizontal cells":"834.4","Sertoli cells":"508.6","Smooth muscle cells":"468.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"48.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"114.7","testis cancer":"109.7"},"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009792","HPA022275"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009792":"AB_2137420","HPA022275":"AB_1853944"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.22e-5"}},{"Gene":"MAP2K3","Gene synonym":["MAPKK3","MEK3","MKK3","PRKMK3"],"Ensembl":"ENSG00000034152","Gene description":"Mitogen-activated protein kinase kinase 3","Uniprot":["P46734"],"Chromosome":"17","Position":"21284672-21315232","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"212.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"229.7","Langerhans cells":"295.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018548"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB018548":"AB_631927"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"}},{"Gene":"MAP2K7","Gene synonym":["Jnkk2","MKK7","PRKMK7"],"Ensembl":"ENSG00000076984","Gene description":"Mitogen-activated protein kinase kinase 7","Uniprot":["O14733"],"Chromosome":"19","Position":"7903843-7914478","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Stress response"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001633","CAB004262","HPA064711"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB004262":"AB_627925","HPA001633":"AB_1079516","HPA064711":"AB_2685331"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.54e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.56e-4"}},{"Gene":"MAP3K1","Gene synonym":["MAPKKK1","MEKK","MEKK1"],"Ensembl":"ENSG00000095015","Gene description":"Mitogen-activated protein kinase kinase kinase 1","Uniprot":["Q13233"],"Chromosome":"5","Position":"56815549-56896152","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"201.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"olfactory bulb":"18.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004500","HPA046509"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004500":"AB_627926","HPA046509":"AB_2679678"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"}},{"Gene":"MAP3K21","Gene synonym":["KIAA1804","MLK4"],"Ensembl":"ENSG00000143674","Gene description":"Mitogen-activated protein kinase kinase kinase 21","Uniprot":["Q5TCX8"],"Chromosome":"1","Position":"233327724-233385148","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"20.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"37.1","Inhibitory neurons":"34.7","Sertoli cells":"24.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"NK-cell":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"NK-cells":"1.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 2","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007636"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007636":"AB_1079392"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"}},{"Gene":"MAP3K3","Gene synonym":["MAPKKK3","MEKK3"],"Ensembl":"ENSG00000198909","Gene description":"Mitogen-activated protein kinase kinase kinase 3","Uniprot":["Q99759"],"Chromosome":"17","Position":"63622415-63696305","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB007764","HPA035410","HPA035411","HPA064376"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB007764":"AB_562314","HPA035410":"AB_2674614","HPA035411":"AB_2674615","HPA064376":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"}},{"Gene":"MAP3K9","Gene synonym":["MEKK9","MLK1","PRKE1"],"Ensembl":"ENSG00000006432","Gene description":"Mitogen-activated protein kinase kinase kinase 9","Uniprot":["P80192"],"Chromosome":"14","Position":"70722526-70809534","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Stress response","Transcription","Transcription regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"22.7","retina":"9.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"48.9","Inhibitory neurons":"56.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 2","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000942"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA000942":"AB_1079360"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"}},{"Gene":"MAPK15","Gene synonym":["ERK7","ERK8"],"Ensembl":"ENSG00000181085","Gene description":"Mitogen-activated protein kinase 15","Uniprot":["Q8TD08"],"Chromosome":"8","Position":"143716340-143722458","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"54.9","fallopian tube":"46.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"57.7","Respiratory ciliated cells":"121.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"18.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Respiratory ciliated cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002704"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA002704":"AB_1079307"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"}},{"Gene":"MAPKAP1","Gene synonym":["MGC2745","MIP1","SIN1"],"Ensembl":"ENSG00000119487","Gene description":"MAPK associated protein 1","Uniprot":["Q9BPZ7"],"Chromosome":"9","Position":"125437393-125707234","Protein class":["Predicted intracellular proteins"],"Biological process":["Stress response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029091","HPA029092"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA029091":"AB_10599732","HPA029092":"AB_10601568"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.23e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"}},{"Gene":"MAPKAPK2","Gene synonym":["MK2"],"Ensembl":"ENSG00000162889","Gene description":"MAPK activated protein kinase 2","Uniprot":["P49137"],"Chromosome":"1","Position":"206684905-206734281","Protein class":["Cancer-related genes","Enzymes","Predicted membrane proteins"],"Biological process":["DNA damage"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"270.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"plasmacytoid DC":"21.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"21.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010297","HPA045556","HPA063708","HPA064435"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"CAB010297":"AB_2250405","HPA045556":"AB_2679367","HPA063708":"AB_2685100","HPA064435":"AB_2685263"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.93e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"}},{"Gene":"MAPKAPK3","Gene synonym":["3pK","MAPKAP3","MK-3","MK3"],"Ensembl":"ENSG00000114738","Gene description":"MAPK activated protein kinase 3","Uniprot":["Q16644"],"Chromosome":"3","Position":"50611520-50649291","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"106.5","heart muscle":"256.3","skeletal muscle":"224.2","tongue":"284.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"237.1","Hofbauer cells":"113.9","monocytes":"174.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"142.8","granulocytes":"126.3","monocytes":"341.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Heart muscle - Cardiomyocytes","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058275"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA058275":"AB_2683663"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.08e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.90e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"}},{"Gene":"MAPKAPK5","Gene synonym":["MK5","PRAK"],"Ensembl":"ENSG00000089022","Gene description":"MAPK activated protein kinase 5","Uniprot":["Q8IW41"],"Chromosome":"12","Position":"111842228-111902222","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004546","HPA015515"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004546":"AB_627910","HPA015515":"AB_1853569"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.98e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"}},{"Gene":"MARCHF1","Gene synonym":["FLJ20668","MARCH-I","MARCH1","RNF171"],"Ensembl":"ENSG00000145416","Gene description":"Membrane associated ring-CH-type finger 1","Uniprot":["Q8TCQ1"],"Chromosome":"4","Position":"163524298-164384050","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Immunity","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"31.6","retina":"27.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"475.8","Oligodendrocyte precursor cells":"948.7","Oligodendrocytes":"1228.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"94","RNA blood cell specific nTPM":{"classical monocyte":"41.8","eosinophil":"25.5","intermediate monocyte":"41.0","memory B-cell":"42.3","myeloid DC":"44.2","naive B-cell":"35.8","non-classical monocyte":"45.4","plasmacytoid DC":"16.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014600","HPA048024"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":["Endoplasmic reticulum","Golgi apparatus"],"Antibody RRID":{"HPA014600":"AB_1853573","HPA048024":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"}},{"Gene":"MARCHF11","Gene synonym":["MARCH-XI","MARCH11","RNF226"],"Ensembl":"ENSG00000183654","Gene description":"Membrane associated ring-CH-type finger 11","Uniprot":["A6NNE9"],"Chromosome":"5","Position":"16067139-16180762","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"testis":"82.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"174.3","Excitatory neurons":"47.6","Inhibitory neurons":"115.1","Spermatocytes":"35.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"Neuroblastoma":"78.9"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"MARCHF2","Gene synonym":["HSPC240","MARCH-II","MARCH2","RNF172"],"Ensembl":"ENSG00000099785","Gene description":"Membrane associated ring-CH-type finger 2","Uniprot":["Q9P0N8"],"Chromosome":"19","Position":"8413270-8439017","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Endocytosis","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014063"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA014063":"AB_1853576"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.48e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.29e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.21e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"}},{"Gene":"MARCHF3","Gene synonym":["MARCH-III","MARCH3","MGC48332","RNF173"],"Ensembl":"ENSG00000173926","Gene description":"Membrane associated ring-CH-type finger 3","Uniprot":["Q86UD3"],"Chromosome":"5","Position":"126867714-127030558","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"86.0","Microglial cells":"111.3","Spermatocytes":"71.8","Syncytiotrophoblasts":"88.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"10.5","naive B-cell":"12.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"12.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Skin - Keratinocyte (granular)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043406"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA043406":"AB_10793947"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"}},{"Gene":"MARCHF4","Gene synonym":["KIAA1399","MARCH-IV","MARCH4","RNF174"],"Ensembl":"ENSG00000144583","Gene description":"Membrane associated ring-CH-type finger 4","Uniprot":["Q9P2E8"],"Chromosome":"2","Position":"216257865-216372483","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"4.4","pituitary gland":"6.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"45.2","Inhibitory neurons":"72.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"1.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells","Stomach - Gastric enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014348"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014348":"AB_1853578"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"}},{"Gene":"MARCHF5","Gene synonym":["FLJ20445","MARCH-V","MARCH5","MITOL","RNF153"],"Ensembl":"ENSG00000198060","Gene description":"Membrane associated ring-CH-type finger 5","Uniprot":["Q9NX47"],"Chromosome":"10","Position":"92291167-92353964","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"167.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056596"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA056596":"AB_2683181"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"}},{"Gene":"MARCHF6","Gene synonym":["MARCH-VI","MARCH6","RNF176","TEB4"],"Ensembl":"ENSG00000145495","Gene description":"Membrane associated ring-CH-type finger 6","Uniprot":["O60337"],"Chromosome":"5","Position":"10353695-10440388","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040841","HPA063246"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA040841":"AB_2677162","HPA063246":"AB_2684970"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-3"}},{"Gene":"MARCHF8","Gene synonym":["c-MIR","CMIR","MARCH-VIII","MARCH8","MIR","RNF178"],"Ensembl":"ENSG00000165406","Gene description":"Membrane associated ring-CH-type finger 8","Uniprot":["Q5T0T0"],"Chromosome":"10","Position":"45454585-45594906","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"292.2","Late spermatids":"413.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014597"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014597":"AB_1853580"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.71e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.64e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"}},{"Gene":"MARCHF9","Gene synonym":["FLJ36578","MARCH9","RNF179"],"Ensembl":"ENSG00000139266","Gene description":"Membrane associated ring-CH-type finger 9","Uniprot":["Q86YJ5"],"Chromosome":"12","Position":"57755103-57760411","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"86.7","Cone photoreceptor cells":"131.0","dendritic cells":"71.1","Rod photoreceptor cells":"191.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"39.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.07e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.54e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.59e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.98e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"MARCO","Gene synonym":["SCARA2","SR-A6"],"Ensembl":"ENSG00000019169","Gene description":"Macrophage receptor with collagenous structure","Uniprot":["Q9UEW3"],"Chromosome":"2","Position":"118942194-118994660","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"94.9","lung":"199.6","lymphoid tissue":"87.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"55.2","Hofbauer cells":"178.9","Kupffer cells":"84.2","Langerhans cells":"58.7","Macrophages":"285.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"21.6"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"4.1","thalamus":"12.6"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"33.7","intermediate monocyte":"56.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"56.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Esophageal cancer":"1.3","head and neck cancer":"1.4","lymphoma":"1.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063793"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"30000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA063793":"AB_2685123"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"}},{"Gene":"MARK1","Gene synonym":["MARK","PAR-1C"],"Ensembl":"ENSG00000116141","Gene description":"Microtubule affinity regulating kinase 1","Uniprot":["Q9P0L2"],"Chromosome":"1","Position":"220528136-220664461","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Autism","Autism spectrum disorder"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"71.5","Excitatory neurons":"168.7","Inhibitory neurons":"166.2","Oligodendrocyte precursor cells":"160.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"12.2"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Lung - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007421","HPA008061"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007421":"AB_1079311","HPA008061":"AB_1079310"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.63e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.23e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"}},{"Gene":"MARK2","Gene synonym":["EMK1","PAR-1","PAR-1B","Par1b"],"Ensembl":"ENSG00000072518","Gene description":"Microtubule affinity regulating kinase 2","Uniprot":["Q7KZI7"],"Chromosome":"11","Position":"63838928-63911020","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Differentiation","Wnt signaling pathway"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038790","HPA074905"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA038790":"AB_10674840","HPA074905":"AB_2686722"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.30e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"}},{"Gene":"MARK3","Gene synonym":["CTAK1","KP78","PAR-1A"],"Ensembl":"ENSG00000075413","Gene description":"Microtubule affinity regulating kinase 3","Uniprot":["P27448"],"Chromosome":"14","Position":"103385377-103503831","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"32","RNA blood cell specific nTPM":{"eosinophil":"101.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"granulocytes":"101.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024652"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024652":"AB_1853582"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"}},{"Gene":"MARK4","Gene synonym":["FLJ90097","KIAA1860","MARKL1","Nbla00650","PAR-1D"],"Ensembl":"ENSG00000007047","Gene description":"Microtubule affinity regulating kinase 4","Uniprot":["Q96L34"],"Chromosome":"19","Position":"45079288-45305284","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","Cilium biogenesis\/degradation","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"46.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039186"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039186":"AB_10796223"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.31e-8"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.05e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"}},{"Gene":"MARVELD1","Gene synonym":["bA548K23.8","FLJ22343","FLJ23440","GB14","MGC4415","MRVLDC1"],"Ensembl":"ENSG00000155254","Gene description":"MARVEL domain containing 1","Uniprot":["Q9BSK0"],"Chromosome":"10","Position":"97713173-97718150","Protein class":["Predicted membrane proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"83.7","Schwann cells":"46.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"3.2","intermediate monocyte":"2.7","myeloid DC":"3.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"dendritic cells":"3.1","monocytes":"3.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Heart muscle - Fibroblasts","Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.85e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.89e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-3"}},{"Gene":"MARVELD2","Gene synonym":["DFNB49","FLJ30532","MRVLDC2","TRIC"],"Ensembl":"ENSG00000152939","Gene description":"MARVEL domain containing 2","Uniprot":["Q8N4S9"],"Chromosome":"5","Position":"69415065-69444330","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"15.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"15.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Liver - Hepatocytes","Skin - Keratinocyte (other)","Testis - Early spermatids","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"8","RNA mouse brain regional specific nTPM":{"cerebellum":"7.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018119","HPA061726"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA018119":"AB_2669771","HPA061726":"AB_2684595"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.84e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"}},{"Gene":"MARVELD3","Gene synonym":["MRVLDC3"],"Ensembl":"ENSG00000140832","Gene description":"MARVEL domain containing 3","Uniprot":["Q96A59"],"Chromosome":"16","Position":"71626161-71642114","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"33.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"86.1","Intestinal goblet cells":"62.6","Paneth cells":"94.2","Proximal enterocytes":"200.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Colon enterocytes","Liver - Hepatocytes","Lung - Alveolar cells type 2","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043514","HPA045471"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Intermediate filaments"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Vesicles"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"HPA043514":"AB_10959475","HPA045471":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.80e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"}},{"Gene":"MAS1","Gene synonym":[],"Ensembl":"ENSG00000130368","Gene description":"MAS1 proto-oncogene, G protein-coupled receptor","Uniprot":["P04201"],"Chromosome":"6","Position":"159890988-159917447","Protein class":["Disease related genes","G-protein coupled receptors","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"brain":"9.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1.9","Cone photoreceptor cells":"1.7","Langerhans cells":"2.1","Melanocytes":"1.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"5.1","hippocampal formation":"9.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"22","RNA mouse brain regional specific nTPM":{"amygdala":"38.5","basal ganglia":"26.6","cerebral cortex":"32.4","hippocampal formation":"64.6","white matter":"18.1"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"amygdala":"5.2","cerebral cortex":"8.0","hippocampal formation":"15.1"},"Antibody":["HPA079325"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA079325":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"MAS1L","Gene synonym":["dJ994E9.2","MAS-L","MRG"],"Ensembl":"ENSG00000204687","Gene description":"MAS1 proto-oncogene like, G protein-coupled receptor","Uniprot":["P35410"],"Chromosome":"6","Position":"29486697-29487956","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"3.1","epididymis":"1.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"97","RNA single cell type specific nTPM":{"granulocytes":"9.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017983"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017983":"AB_1849332"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MATK","Gene synonym":["CHK","CTK","DKFZp434N1212","HHYLTK","HYL","HYLTK","Lsk","MGC1708","MGC2101"],"Ensembl":"ENSG00000007264","Gene description":"Megakaryocyte-associated tyrosine kinase","Uniprot":["P42679"],"Chromosome":"19","Position":"3777970-3802129","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"20.5","brain":"41.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"70.6","Hofbauer cells":"50.4","NK-cells":"303.1","T-cells":"94.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"76.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"57","RNA blood lineage specific nTPM":{"NK-cells":"76.8","T-cells":"46.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"52.8"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Breast - T-cells","Heart muscle - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004847","HPA066547"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytokinetic bridge","Mitotic spindle","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Microtubules"],"Subcellular additional location":["Cytokinetic bridge","Mitotic spindle","Centriolar satellite","Cytosol"],"Antibody RRID":{"HPA004847":"AB_1079316","HPA066547":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.27e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"}},{"Gene":"MAVS","Gene synonym":["Cardif","IPS-1","KIAA1271","VISA"],"Ensembl":"ENSG00000088888","Gene description":"Mitochondrial antiviral signaling protein","Uniprot":["Q7Z434"],"Chromosome":"20","Position":"3846799-3876123","Protein class":["Predicted membrane proteins"],"Biological process":["Antiviral defense","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009187","HPA049850","HPA053524"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"600000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB009187":null,"HPA049850":"AB_2680912","HPA053524":"AB_2682177"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.81e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.13e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"}},{"Gene":"MAZ","Gene synonym":["Pur-1","ZF87","Zif87","ZNF801"],"Ensembl":"ENSG00000103495","Gene description":"MYC associated zinc finger protein","Uniprot":["P56270"],"Chromosome":"16","Position":"29806106-29811164","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048315","HPA059495","HPA065930"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA048315":"AB_2680353","HPA059495":"AB_2684039","HPA065930":"AB_2685579"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.15e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.22e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"}},{"Gene":"MBD2","Gene synonym":[],"Ensembl":"ENSG00000134046","Gene description":"Methyl-CpG binding domain protein 2","Uniprot":["Q9UBB5"],"Chromosome":"18","Position":"54151606-54224669","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"303.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"5.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037282","HPA067582","HPA067615"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB037282":"AB_477234","HPA067582":"AB_2685866","HPA067615":"AB_2685872"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.49e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"}},{"Gene":"MBOAT1","Gene synonym":["dJ434O11.1","LPEAT1","MGC44669","OACT1"],"Ensembl":"ENSG00000172197","Gene description":"Membrane bound O-acyltransferase domain containing 1","Uniprot":["Q6ZNC8"],"Chromosome":"6","Position":"20099684-20212469","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"51.3","Paneth cells":"76.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.15e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"}},{"Gene":"MBOAT2","Gene synonym":["FLJ14415","FLJ90298","OACT2"],"Ensembl":"ENSG00000143797","Gene description":"Membrane bound O-acyltransferase domain containing 2","Uniprot":["Q6ZWT7"],"Chromosome":"2","Position":"8852690-9003709","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"165.7","Erythroid cells":"118.9","Excitatory neurons":"132.5","Oligodendrocyte precursor cells":"169.9","Oligodendrocytes":"217.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"4.7","eosinophil":"1.7","neutrophil":"4.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"4.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014836"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA014836":"AB_1854745"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.13e-9"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.32e-4"}},{"Gene":"MBOAT4","Gene synonym":["FKSG89","GOAT","OACT4"],"Ensembl":"ENSG00000177669","Gene description":"Membrane bound O-acyltransferase domain containing 4","Uniprot":["Q96T53"],"Chromosome":"8","Position":"30131671-30144665","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"3.6","stomach 1":"3.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"3.5","Cholangiocytes":"7.7","Ductal cells":"3.4","Excitatory neurons":"2.4","Gastric mucus-secreting cells":"6.0","Inhibitory neurons":"3.0","Oligodendrocyte precursor cells":"2.9","Oligodendrocytes":"5.1","Schwann cells":"4.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"1.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric enteroendocrine cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044509"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA044509":"AB_2678966"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"}},{"Gene":"MBOAT7","Gene synonym":["BB1","hMBOA-7","LENG4","LPLAT"],"Ensembl":"ENSG00000125505","Gene description":"Membrane bound O-acyltransferase domain containing 7","Uniprot":["Q96N66"],"Chromosome":"19","Position":"54173412-54189882","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"108.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"157.3","eosinophil":"265.9","neutrophil":"239.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"265.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055967"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA055967":"AB_2682990"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.55e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.13e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.62e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.31e-4"}},{"Gene":"MBTPS1","Gene synonym":["KIAA0091","PCSK8","S1P","SKI-1"],"Ensembl":"ENSG00000140943","Gene description":"Membrane bound transcription factor peptidase, site 1","Uniprot":["Q14703"],"Chromosome":"16","Position":"84053761-84116942","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"312.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056109"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056109":"AB_2683040"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.21e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"}},{"Gene":"MBTPS2","Gene synonym":["KFSD","S2P"],"Ensembl":"ENSG00000012174","Gene description":"Membrane bound transcription factor peptidase, site 2","Uniprot":["O43462"],"Chromosome":"X","Position":"21839617-21885423","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Ichthyosis","Osteogenesis imperfecta","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005494","CAB009486"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm","Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009486":"AB_2140370","HPA005494":"AB_1079329"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"}},{"Gene":"MC1R","Gene synonym":["MSH-R"],"Ensembl":"ENSG00000258839","Gene description":"Melanocortin 1 receptor","Uniprot":["Q01726"],"Chromosome":"16","Position":"89912119-89920973","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"27.9","testis":"29.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"9.0","Melanocytes":"20.9","Spermatocytes":"10.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"melanoma":"6.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"46.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-7"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.88e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"}},{"Gene":"MC2R","Gene synonym":["ACTHR"],"Ensembl":"ENSG00000185231","Gene description":"Melanocortin 2 receptor","Uniprot":["Q01718"],"Chromosome":"18","Position":"13882044-13915707","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"33","RNA tissue specific nTPM":{"adrenal gland":"57.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079148"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA079148":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MC3R","Gene synonym":["MC3"],"Ensembl":"ENSG00000124089","Gene description":"Melanocortin 3 receptor","Uniprot":["P41968"],"Chromosome":"20","Position":"56248732-56249815","Protein class":["G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":["Biological rhythms"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"114","RNA tissue specific nTPM":{"brain":"14.4"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"9","RNA brain regional specific nTPM":{"hypothalamus":"14.4","thalamus":"12.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"4.8","hypothalamus":"4.5","thalamus":"1.3"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"basal ganglia":"3.2","hypothalamus":"2.2","thalamus":"2.6"},"Antibody":["HPA074739"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074739":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MC4R","Gene synonym":[],"Ensembl":"ENSG00000166603","Gene description":"Melanocortin 4 receptor","Uniprot":["P32245"],"Chromosome":"18","Position":"60371062-60372775","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","FDA approved drug targets","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"3.5","fallopian tube":"3.0","retina":"3.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Bipolar cells":"7.1","Cone photoreceptor cells":"5.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Plasma cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"10.2"},"Antibody":["HPA016719"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016719":"AB_1853617"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"MC5R","Gene synonym":[],"Ensembl":"ENSG00000176136","Gene description":"Melanocortin 5 receptor","Uniprot":["P33032"],"Chromosome":"18","Position":"13824149-13827323","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"2.4","lymphoid tissue":"1.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"6.6","Squamous epithelial cells":"2.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042365","HPA058088"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA042365":"AB_2677961","HPA058088":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MCAM","Gene synonym":["CD146","HEMCAM","MelCAM","METCAM","MUC18"],"Ensembl":"ENSG00000076706","Gene description":"Melanoma cell adhesion molecule","Uniprot":["P43121"],"Chromosome":"11","Position":"119308529-119321521","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"118.0","Endothelial cells":"132.4","Muller glia cells":"83.7","Sertoli cells":"196.3","Smooth muscle cells":"399.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"83.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"278.5"},"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Liver - Vascular Endothelial cells","Prostate - Smooth muscle cells","Testis - Endothelial cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002147","HPA008848"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1900000000","Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002147":"AB_563499","HPA008848":"AB_1078445"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.61e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"}},{"Gene":"MCEMP1","Gene synonym":["C19orf59","MGC132456"],"Ensembl":"ENSG00000183019","Gene description":"Mast cell expressed membrane protein 1","Uniprot":["Q8IX19"],"Chromosome":"19","Position":"7676628-7679826","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"bone marrow":"65.9","lung":"74.2","lymphoid tissue":"35.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"74.2","Kupffer cells":"60.2","Langerhans cells":"20.6","Macrophages":"104.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"3.7"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"2.1"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"102.1","neutrophil":"45.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"45.9","monocytes":"102.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"13.4"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Colon - Neutrophils","Heart muscle - Neutrophils","Liver - Neutrophils","Skeletal muscle - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"1.3"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014731"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014731":"AB_1845619"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"}},{"Gene":"MCF2L","Gene synonym":["ARHGEF14","DBS","KIAA0362","OST"],"Ensembl":"ENSG00000126217","Gene description":"MCF.2 cell line derived transforming sequence like","Uniprot":["O15068"],"Chromosome":"13","Position":"112894378-113099742","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"134.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"127.9","Bipolar cells":"62.9","Cone photoreceptor cells":"98.2","Endothelial cells":"66.6","Intestinal goblet cells":"66.0","Microglial cells":"90.3","Oligodendrocytes":"70.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"33.2"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.01e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.36e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.63e-5"}},{"Gene":"MCHR1","Gene synonym":["GPR24","MCH1R","SLC1"],"Ensembl":"ENSG00000128285","Gene description":"Melanin concentrating hormone receptor 1","Uniprot":["Q99705"],"Chromosome":"22","Position":"40678750-40682814","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.7","endometrium 1":"3.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"3.7","Inhibitory neurons":"4.2","Leydig cells":"3.4","Melanocytes":"10.4","Microglial cells":"2.7","Oligodendrocyte precursor cells":"1.9","Pancreatic endocrine cells":"3.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"4.9","liver cancer":"1.5","melanoma":"3.1","renal cancer":"2.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"16.8","testis cancer":"4.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"22.9"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"}},{"Gene":"MCHR2","Gene synonym":["GPR145","MCH2","MCH2R","SLT"],"Ensembl":"ENSG00000152034","Gene description":"Melanin concentrating hormone receptor 2","Uniprot":["Q969V1"],"Chromosome":"6","Position":"99918519-99994247","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"3.5","testis":"1.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"31","RNA single cell type specific nTPM":{"Excitatory neurons":"43.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"3.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MCL1","Gene synonym":["BCL2L3","Mcl-1"],"Ensembl":"ENSG00000143384","Gene description":"MCL1 apoptosis regulator, BCL2 family member","Uniprot":["Q07820"],"Chromosome":"1","Position":"150560895-150579738","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"685.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"1033.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"106.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002781","HPA008455","HPA031125","CAB068195"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB002781":null,"CAB068195":"AB_2665695","HPA008455":"AB_1079334","HPA031125":"AB_10602026"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"}},{"Gene":"MCM5","Gene synonym":["CDC46"],"Ensembl":"ENSG00000100297","Gene description":"Minichromosome maintenance complex component 5","Uniprot":["P33992"],"Chromosome":"22","Position":"35400134-35425431","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA replication"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"138.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"148.5","Erythroid cells":"111.8","Plasma cells":"75.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000101","HPA000845","HPA052880"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000101":"AB_2235163","HPA000845":"AB_1079338","HPA052880":"AB_2681979"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.81e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.78e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.95e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"}},{"Gene":"MCMDC2","Gene synonym":["C8orf45","FLJ25692"],"Ensembl":"ENSG00000178460","Gene description":"Minichromosome maintenance domain containing 2","Uniprot":["Q4G0Z9"],"Chromosome":"8","Position":"66870749-66922048","Protein class":["Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Meiosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"11.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"66.1","Spermatocytes":"62.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026522"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA026522":"AB_10603453"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-5"}},{"Gene":"MCOLN1","Gene synonym":["ML4","MLIV","MST080","MSTP080","TRPM-L1","TRPML1"],"Ensembl":"ENSG00000090674","Gene description":"Mucolipin 1","Uniprot":["Q9GZU1"],"Chromosome":"19","Position":"7522624-7534009","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Adaptive immunity","Calcium transport","Immunity","Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant","Mucolipidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"102.8","Macrophages":"86.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"117.5","classical monocyte":"45.2","eosinophil":"105.7","intermediate monocyte":"95.5","neutrophil":"41.1","non-classical monocyte":"105.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"117.5","monocytes":"105.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Lung - Macrophages","Prostate - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031763","CAB032637","HPA069495"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB032637":"AB_2142964","HPA031763":"AB_10600822","HPA069495":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.60e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.67e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"}},{"Gene":"MCOLN2","Gene synonym":["FLJ36691","TRP-ML2","TRPML2"],"Ensembl":"ENSG00000153898","Gene description":"Mucolipin 2","Uniprot":["Q8IZK6"],"Chromosome":"1","Position":"84925583-84997113","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Adaptive immunity","Calcium transport","Immunity","Innate immunity","Ion transport","Protein transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"15.1","lymphoid tissue":"13.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"40.5","dendritic cells":"80.8","Early spermatids":"61.3","Glandular and luminal cells":"27.7","Langerhans cells":"116.1","Schwann cells":"32.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"29.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"B-cells":"10.3","dendritic cells":"29.7","T-cells":"8.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"29.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Liver - T-cells","Testis - Early spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019114"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019114":"AB_1853645"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"}},{"Gene":"MCOLN3","Gene synonym":["FLJ11006","TRP-ML3","TRPML3"],"Ensembl":"ENSG00000055732","Gene description":"Mucolipin 3","Uniprot":["Q8TDD5"],"Chromosome":"1","Position":"85018082-85048500","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adrenal gland":"43.5","epididymis":"13.9","parathyroid gland":"35.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Enteroendocrine cells":"54.3","Melanocytes":"214.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"melanoma":"8.0"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"4.0","hippocampal formation":"3.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"12.6"},"RNA tissue cell type enrichment":["Lung - Fibroblast_1","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018106","HPA062137"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA018106":"AB_1853647","HPA062137":"AB_2684695"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"}},{"Gene":"MCTP1","Gene synonym":["FLJ22344"],"Ensembl":"ENSG00000175471","Gene description":"Multiple C2 and transmembrane domain containing 1","Uniprot":["Q6DN14"],"Chromosome":"5","Position":"94703741-95284575","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"45.3","brain":"37.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"113.0","Excitatory neurons":"503.0","Inhibitory neurons":"402.8","Oligodendrocyte precursor cells":"252.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"46","RNA blood cell specific nTPM":{"basophil":"37.0","classical monocyte":"28.6","eosinophil":"13.2","intermediate monocyte":"41.4","myeloid DC":"22.3","neutrophil":"40.5","non-classical monocyte":"40.6","plasmacytoid DC":"11.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"54","RNA blood lineage specific nTPM":{"dendritic cells":"22.3","granulocytes":"40.5","monocytes":"41.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075887"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA075887":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"}},{"Gene":"MCTP2","Gene synonym":["FLJ11175","FLJ33303"],"Ensembl":"ENSG00000140563","Gene description":"Multiple C2 and transmembrane domain containing 2","Uniprot":["Q6DN12"],"Chromosome":"15","Position":"94231538-94483952","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"57.0","NK-cells":"133.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"6.8"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"32.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Prostate - Prostate basal glandular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051176","HPA070541"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA051176":"AB_2681373","HPA070541":"AB_2686277"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.18e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"}},{"Gene":"MCU","Gene synonym":["C10orf42","CCDC109A","FLJ46135"],"Ensembl":"ENSG00000156026","Gene description":"Mitochondrial calcium uniporter","Uniprot":["Q8NE86"],"Chromosome":"10","Position":"72692131-72887694","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"53.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"57.4","Gastric mucus-secreting cells":"68.6","Inhibitory neurons":"64.1","Oligodendrocyte precursor cells":"69.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016480"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA016480":"AB_2071893"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.06e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"}},{"Gene":"MCUB","Gene synonym":["CCDC109B","FLJ20647"],"Ensembl":"ENSG00000005059","Gene description":"Mitochondrial calcium uniporter dominant negative subunit beta","Uniprot":["Q9NWR8"],"Chromosome":"4","Position":"109560209-109688719","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"32.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"133.8","Extravillous trophoblasts":"97.0","Hofbauer cells":"125.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048776"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Nucleoplasm","Vesicles","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA048776":"AB_2680518"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.35e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"}},{"Gene":"MCUR1","Gene synonym":["C6orf79","CCDC90A","FLJ20958"],"Ensembl":"ENSG00000050393","Gene description":"Mitochondrial calcium uniporter regulator 1","Uniprot":["Q96AQ8"],"Chromosome":"6","Position":"13786557-13814568","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"81.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"213.5","Rod photoreceptor cells":"258.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078654"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078654":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.51e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"}},{"Gene":"MDFI","Gene synonym":["I-mfa"],"Ensembl":"ENSG00000112559","Gene description":"MyoD family inhibitor","Uniprot":["Q99750"],"Chromosome":"6","Position":"41636882-41654244","Protein class":["Predicted intracellular proteins"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"44.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"228.7","Extravillous trophoblasts":"114.6","Syncytiotrophoblasts":"120.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"134.8"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"cerebellum":"17.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049973"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA049973":"AB_2680975"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.11e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.85e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"}},{"Gene":"MDFIC","Gene synonym":["HIC","MDFIC1"],"Ensembl":"ENSG00000135272","Gene description":"MyoD family inhibitor domain containing","Uniprot":["Q9P1T7"],"Chromosome":"7","Position":"114922359-115019202","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Muller glia cells":"106.4","T-cells":"77.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030716"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA030716":"AB_10671364"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.65e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"}},{"Gene":"MDFIC2","Gene synonym":[],"Ensembl":"ENSG00000242120","Gene description":"MyoD family inhibitor domain containing 2","Uniprot":["A0A1B0GVS7"],"Chromosome":"3","Position":"70194479-70312638","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"4.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MDGA2","Gene synonym":["MAMDC1"],"Ensembl":"ENSG00000139915","Gene description":"MAM domain containing glycosylphosphatidylinositol anchor 2","Uniprot":["Q7Z553"],"Chromosome":"14","Position":"46839629-47675605","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"8.0","retina":"4.4","testis":"3.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Excitatory neurons":"1534.8","Inhibitory neurons":"1182.2","Oligodendrocyte precursor cells":"1889.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"2.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003084"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003084":"AB_1079302"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"MDM1","Gene synonym":[],"Ensembl":"ENSG00000111554","Gene description":"Mdm1 nuclear protein","Uniprot":["Q8TC05"],"Chromosome":"12","Position":"68272443-68332381","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"50.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040411","HPA041594"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA040411":"AB_10805711","HPA041594":"AB_10793968"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.01e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-3"}},{"Gene":"MDM2","Gene synonym":["HDM2","MGC5370"],"Ensembl":"ENSG00000135679","Gene description":"MDM2 proto-oncogene","Uniprot":["Q00987"],"Chromosome":"12","Position":"68808177-68850686","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"254.8","Skeletal myocytes":"198.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000086","CAB016303","CAB079977"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB000086":"AB_563872","CAB016303":"AB_627920","CAB079977":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.23e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.51e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"}},{"Gene":"MED12L","Gene synonym":["KIAA1635","TNRC11L","TRALP","TRALPUSH"],"Ensembl":"ENSG00000144893","Gene description":"Mediator complex subunit 12L","Uniprot":["Q86YW9"],"Chromosome":"3","Position":"151085697-151437072","Protein class":["Disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Repressor"],"Disease involvement":["Autism spectrum disorder","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"choroid plexus":"24.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"371.4","Excitatory neurons":"298.5","Inhibitory neurons":"117.9","Oligodendrocyte precursor cells":"216.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.3","plasmacytoid DC":"2.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036807"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA036807":"AB_10670242"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"}},{"Gene":"MED16","Gene synonym":["DRIP92","THRAP5","TRAP95"],"Ensembl":"ENSG00000175221","Gene description":"Mediator complex subunit 16","Uniprot":["Q9Y2X0"],"Chromosome":"19","Position":"867630-893218","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030685","HPA046495"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA030685":"AB_10601872","HPA046495":"AB_2679674"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.46e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"}},{"Gene":"MED17","Gene synonym":["CRSP6","CRSP77","DRIP80","SRB4","TRAP80"],"Ensembl":"ENSG00000042429","Gene description":"Mediator complex subunit 17","Uniprot":["Q9NVC6"],"Chromosome":"11","Position":"93784227-93814963","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"50.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"2.3","cerebral cortex":"1.3","white matter":"1.7"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046619"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA046619":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.94e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.04e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"}},{"Gene":"MED23","Gene synonym":["CRSP130","CRSP3","DRIP130","MRT18","Sur2"],"Ensembl":"ENSG00000112282","Gene description":"Mediator complex subunit 23","Uniprot":["Q9ULK4"],"Chromosome":"6","Position":"131573966-131628242","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"70.9","Inhibitory neurons":"65.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070341"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA070341":"AB_2686257"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"}},{"Gene":"MED24","Gene synonym":["CRSP100","CRSP4","DRIP100","KIAA0130","MED5","THRAP4","TRAP100"],"Ensembl":"ENSG00000008838","Gene description":"Mediator complex subunit 24","Uniprot":["O75448"],"Chromosome":"17","Position":"40019097-40061215","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"196.1","Ionocytes":"223.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"}},{"Gene":"MED27","Gene synonym":["CRSP34","CRSP8","MED3","TRAP37"],"Ensembl":"ENSG00000160563","Gene description":"Mediator complex subunit 27","Uniprot":["Q6P2C8"],"Chromosome":"9","Position":"131852928-132079867","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":["Cataract","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"86.5","Oligodendrocytes":"122.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007002"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA007002":"AB_1078574"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.59e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"}},{"Gene":"MEGF10","Gene synonym":["KIAA1780","SR-F3"],"Ensembl":"ENSG00000145794","Gene description":"Multiple EGF like domains 10","Uniprot":["Q96KG7"],"Chromosome":"5","Position":"127290796-127465737","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Myogenesis","Phagocytosis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"52.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"211.6","Oligodendrocyte precursor cells":"93.4","Oligodendrocytes":"360.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Sarcoma":"10.4","skin cancer":"6.0"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Liver - Hepatocytes","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011401"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"73000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA011401":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"}},{"Gene":"MEGF11","Gene synonym":["DKFZp434L121","KIAA1781"],"Ensembl":"ENSG00000157890","Gene description":"Multiple EGF like domains 11","Uniprot":["A6BM72"],"Chromosome":"15","Position":"65895079-66253747","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"23.0","fallopian tube":"7.8","kidney":"8.4","retina":"14.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"159.1","Late spermatids":"189.4","Oligodendrocyte precursor cells":"440.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"endometrial cancer":"0.7","glioma":"2.3","renal cancer":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric enteroendocrine cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"cerebellum":"35.0"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"cerebellum":"25.8"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"}},{"Gene":"MEGF8","Gene synonym":["C19orf49","EGFL4","FLJ22365","SBP1"],"Ensembl":"ENSG00000105429","Gene description":"Multiple EGF like domains 8","Uniprot":["Q7Z7M0"],"Chromosome":"19","Position":"42325609-42378769","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Craniosynostosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"38.8","Horizontal cells":"66.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049248"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"510000000","Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049248":"AB_2680691"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.03e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.17e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"}},{"Gene":"MEGF9","Gene synonym":["EGFL5"],"Ensembl":"ENSG00000106780","Gene description":"Multiple EGF like domains 9","Uniprot":["Q9H1U4"],"Chromosome":"9","Position":"120600811-120714470","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"68.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"219.6","Alveolar cells type 2":"153.1","Astrocytes":"138.5","Cone photoreceptor cells":"249.9","Oligodendrocytes":"227.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"25.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"25.2","monocytes":"7.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014319","HPA050238"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"96000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA014319":"AB_1848035","HPA050238":"AB_2681060"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.48e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"}},{"Gene":"MEI1","Gene synonym":["MGC40042","SPATA38"],"Ensembl":"ENSG00000167077","Gene description":"Meiotic double-stranded break formation protein 1","Uniprot":["Q5TIA1"],"Chromosome":"22","Position":"41699503-41799456","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Meiosis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"22.4","testis":"39.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"59.8","Late spermatids":"54.7","NK-cells":"26.3","Plasma cells":"96.8","Spermatocytes":"43.7","T-cells":"25.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"5.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"11.7"},"RNA tissue cell type enrichment":["Breast - Plasma cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"olfactory bulb":"1.4"},"Antibody":["HPA049240"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049240":"AB_2680689"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.59e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"}},{"Gene":"MEIS3","Gene synonym":["DKFZp547H236","MRG2"],"Ensembl":"ENSG00000105419","Gene description":"Meis homeobox 3","Uniprot":["Q99687"],"Chromosome":"19","Position":"47403124-47419527","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"102.3","endometrium 1":"77.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"22.4","Excitatory neurons":"38.6","Horizontal cells":"41.0","Late spermatids":"59.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"69.1"},"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Heart muscle - Fibroblasts","Lung - Fibroblast_2","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046699"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA046699":"AB_2616456"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.78e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"}},{"Gene":"MELK","Gene synonym":["KIAA0175"],"Ensembl":"ENSG00000165304","Gene description":"Maternal embryonic leucine zipper kinase","Uniprot":["Q14680"],"Chromosome":"9","Position":"36572862-36677683","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cell cycle"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"10.0","lymphoid tissue":"21.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"17.0","Erythroid cells":"18.2","Extravillous trophoblasts":"47.1","Spermatocytes":"23.9","Spermatogonia":"19.6","Undifferentiated cells":"17.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"T-reg":"1.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"1.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Mitotic cells (Colon)","Heart muscle - Mitotic cells (Heart)","Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Testis - Spermatocytes","Thyroid - Mitotic cells (Thyroid)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017214"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017214":"AB_1853798"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.91e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.99e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.58e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"}},{"Gene":"MELTF","Gene synonym":["CD228","FLJ38863","MAP97","MFI2","MGC4856","MTf","MTF1"],"Ensembl":"ENSG00000163975","Gene description":"Melanotransferrin","Uniprot":["P08582"],"Chromosome":"3","Position":"196988621-197029817","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Ion transport","Iron transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"35.1","salivary gland":"68.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"32.1","granulocytes":"42.5","Thymic epithelial cells":"33.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"32.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"178.6"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004880"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"41000000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004880":"AB_1853844"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"}},{"Gene":"MEMO1","Gene synonym":["C2orf4","CGI-27","MEMO"],"Ensembl":"ENSG00000162959","Gene description":"Mediator of cell motility 1","Uniprot":["Q9Y316"],"Chromosome":"2","Position":"31865060-32011230","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"68.6","Excitatory neurons":"113.3","Inhibitory neurons":"108.6","Microglial cells":"97.6","Oligodendrocyte precursor cells":"101.6","Oligodendrocytes":"126.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042603","HPA057952"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9100","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042603":"AB_10806243","HPA057952":"AB_2683562"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"}},{"Gene":"MEN1","Gene synonym":[],"Ensembl":"ENSG00000133895","Gene description":"Menin 1","Uniprot":["O00255"],"Chromosome":"11","Position":"64803510-64811294","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030342"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA030342":"AB_10610138"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.31e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"}},{"Gene":"MEP1A","Gene synonym":["PPHA"],"Ensembl":"ENSG00000112818","Gene description":"Meprin A subunit alpha","Uniprot":["Q16819"],"Chromosome":"6","Position":"46793389-46839778","Protein class":["Enzymes","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"101","RNA tissue specific nTPM":{"intestine":"467.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Proximal enterocytes":"811.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"38.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"colorectal cancer":"6.7","Gastric cancer":"2.4","liver cancer":"9.5"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025163","HPA029416"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025163":null,"HPA029416":"AB_10600823"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"}},{"Gene":"MEP1B","Gene synonym":[],"Ensembl":"ENSG00000141434","Gene description":"Meprin A subunit beta","Uniprot":["Q16820"],"Chromosome":"18","Position":"32185069-32220404","Protein class":["Enzymes","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Inflammatory response"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"55","RNA tissue specific nTPM":{"intestine":"363.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"50","RNA single cell type specific nTPM":{"Proximal enterocytes":"202.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"pancreatic cancer":"3.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"colorectal cancer":"1.7","Myeloma":"2.7"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029119"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"310000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029119":"AB_2672913"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"}},{"Gene":"MERTK","Gene synonym":["c-Eyk","mer","RP38","Tyro12"],"Ensembl":"ENSG00000153208","Gene description":"MER proto-oncogene, tyrosine kinase","Uniprot":["Q12866"],"Chromosome":"2","Position":"111898607-112029561","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant","Proto-oncogene","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"157.5","Kupffer cells":"55.8","Macrophages":"69.1","Microglial cells":"121.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"intermediate monocyte":"8.6","non-classical monocyte":"5.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"50","RNA blood lineage specific nTPM":{"monocytes":"8.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Heart muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036196","HPA075622"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane","Midbody","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"65000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Endoplasmic reticulum","Midbody","Cytosol"],"Antibody RRID":{"HPA036196":"AB_10670676","HPA075622":"AB_2686759"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.74e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"}},{"Gene":"MEST","Gene synonym":["PEG1"],"Ensembl":"ENSG00000106484","Gene description":"Mesoderm specific transcript","Uniprot":["Q5EB52"],"Chromosome":"7","Position":"130486171-130506465","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"placenta":"771.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cytotrophoblasts":"839.0","Syncytiotrophoblasts":"825.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD8 T-cell":"24.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"9.1","granulocytes":"19.4","T-cells":"24.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"719.5","Uterine cancer":"629.7"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005623"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA005623":"AB_1079364"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.20e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"}},{"Gene":"MET","Gene synonym":["DFNB97","HGFR","RCCP2"],"Ensembl":"ENSG00000105976","Gene description":"MET proto-oncogene, receptor tyrosine kinase","Uniprot":["P08581"],"Chromosome":"7","Position":"116672196-116798377","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","FDA approved drug targets","Non-syndromic deafness","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"42.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"91.1","Cytotrophoblasts":"76.5","Glandular and luminal cells":"140.3","Salivary duct cells":"115.3","Thymic epithelial cells":"73.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"7.5","hippocampal formation":"6.6","midbrain":"2.5","pons":"4.9","white matter":"7.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 2","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005282","CAB018577","HPA055607"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":179000000,"Blood concentration - Conc. blood MS [pg\/L]":"100000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005282":"AB_631940","CAB018577":"AB_649068","HPA055607":"AB_2682860"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.75e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.21e-7"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"}},{"Gene":"METTL14","Gene synonym":["KIAA1627"],"Ensembl":"ENSG00000145388","Gene description":"Methyltransferase like 14","Uniprot":["Q9HCE5"],"Chromosome":"4","Position":"118685392-118715433","Protein class":["Cancer-related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["RNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"109.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038002"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA038002":"AB_10672401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.46e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-3"}},{"Gene":"METTL21A","Gene synonym":["FAM119A","HCA557b","HSPA-KMT","LOC151194"],"Ensembl":"ENSG00000144401","Gene description":"Methyltransferase like 21A","Uniprot":["Q8WXB1"],"Chromosome":"2","Position":"207580631-207625928","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"113.7","Langerhans cells":"102.9","Paneth cells":"112.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034712"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA034712":"AB_10670160"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.87e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.43e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"}},{"Gene":"METTL25","Gene synonym":["C12orf26","FLJ22789"],"Ensembl":"ENSG00000127720","Gene description":"Methyltransferase like 25","Uniprot":["Q8N6Q8"],"Chromosome":"12","Position":"82358528-82479239","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"23.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"66.1","Excitatory neurons":"62.3","Inhibitory neurons":"57.1","Oligodendrocyte precursor cells":"85.2","Oligodendrocytes":"93.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039534","HPA041207"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Plasma membrane","Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039534":"AB_10794749","HPA041207":"AB_10794406"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"}},{"Gene":"METTL2B","Gene synonym":["FLJ11350","METL","METTL2"],"Ensembl":"ENSG00000165055","Gene description":"Methyltransferase like 2B","Uniprot":["Q6P1Q9"],"Chromosome":"7","Position":"128476729-128506602","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["tRNA processing"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"}},{"Gene":"METTL6","Gene synonym":["MGC24132"],"Ensembl":"ENSG00000206562","Gene description":"Methyltransferase like 6","Uniprot":["Q8TCB7"],"Chromosome":"3","Position":"15381275-15440566","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"253.5","Late spermatids":"126.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035166"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035166":"AB_10602709"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.66e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"}},{"Gene":"METTL7A","Gene synonym":["DKFZP586A0522"],"Ensembl":"ENSG00000185432","Gene description":"Methyltransferase like 7A","Uniprot":["Q9H8H3"],"Chromosome":"12","Position":"50923472-50932510","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"440.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"812.4","Kupffer cells":"291.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"95.7","classical monocyte":"35.7","eosinophil":"70.7","intermediate monocyte":"38.0","memory B-cell":"32.4","myeloid DC":"31.0","naive B-cell":"34.4","non-classical monocyte":"59.5","plasmacytoid DC":"25.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"83.8"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017434"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"HPA017434":"AB_1853835"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"}},{"Gene":"MFAP3","Gene synonym":[],"Ensembl":"ENSG00000037749","Gene description":"Microfibril associated protein 3","Uniprot":["P55082"],"Chromosome":"5","Position":"154038959-154220478","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015883","HPA049198"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA015883":"AB_1853840","HPA049198":"AB_2680672"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.28e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-3"}},{"Gene":"MFAP3L","Gene synonym":["KIAA0626","NYD-sp9"],"Ensembl":"ENSG00000198948","Gene description":"Microfibril associated protein 3 like","Uniprot":["O75121"],"Chromosome":"4","Position":"169986597-170033031","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"65.5","choroid plexus":"88.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Late spermatids":"1878.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"5.7","eosinophil":"1.8","neutrophil":"3.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"5.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"19.1"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017986","HPA062306","HPA077490"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA017986":"AB_1853842","HPA062306":null,"HPA077490":"AB_2686842"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.42e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"}},{"Gene":"MFF","Gene synonym":["C2orf33","GL004"],"Ensembl":"ENSG00000168958","Gene description":"Mitochondrial fission factor","Uniprot":["Q9GZY8"],"Chromosome":"2","Position":"227325151-227357836","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"998.2","Late spermatids":"1810.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010968","HPA074625"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"62000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA010968":"AB_1845714","HPA074625":"AB_2686704"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"}},{"Gene":"MFN1","Gene synonym":["FLJ20693"],"Ensembl":"ENSG00000171109","Gene description":"Mitofusin 1","Uniprot":["Q8IWA4"],"Chromosome":"3","Position":"179347709-179394936","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"90.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033437","HPA059230"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB033437":"AB_2250540","HPA059230":"AB_2683952"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.70e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.11e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.08e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"}},{"Gene":"MFN2","Gene synonym":["CMT2A2","CPRP1","KIAA0214","MARF"],"Ensembl":"ENSG00000116688","Gene description":"Mitofusin 2","Uniprot":["O95140"],"Chromosome":"1","Position":"11980181-12015211","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Autophagy","Unfolded protein response"],"Molecular function":["Hydrolase"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"270.4","skeletal muscle":"310.5","tongue":"337.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cardiomyocytes":"404.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030554","CAB079902"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB079902":"AB_2724683","HPA030554":"AB_10603018"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.36e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"}},{"Gene":"MFRP","Gene synonym":["C1QTNF5","FLJ30570","NNO2","rd6"],"Ensembl":"ENSG00000235718","Gene description":"Membrane frizzled-related protein","Uniprot":["Q9BY79"],"Chromosome":"11","Position":"119338942-119346705","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Microphthalmia","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"choroid plexus":"355.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"hippocampal formation":"24.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"3.5","hippocampal formation":"11.8","pons and medulla":"10.3","thalamus":"8.4"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"medulla oblongata":"17.6"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MFSD1","Gene synonym":["FLJ14153","Minerva","UG0581B09"],"Ensembl":"ENSG00000118855","Gene description":"Major facilitator superfamily domain containing 1","Uniprot":["Q9H3U5"],"Chromosome":"3","Position":"158732198-158829719","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"216.2","Kupffer cells":"211.1","Macrophages":"207.6","monocytes":"150.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"254.5","granulocytes":"246.0","monocytes":"288.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Colon - Macrophages","Lung - Macrophages","Pancreas - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065858"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA065858":"AB_2685569"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.60e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"}},{"Gene":"MFSD10","Gene synonym":["IT10C3","TETRAN"],"Ensembl":"ENSG00000109736","Gene description":"Major facilitator superfamily domain containing 10","Uniprot":["Q14728"],"Chromosome":"4","Position":"2930561-2934834","Protein class":["Predicted membrane proteins"],"Biological process":["Apoptosis","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"241.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043209"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA043209":"AB_2678364"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.68e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"}},{"Gene":"MFSD11","Gene synonym":["FLJ20226","FLJ22196"],"Ensembl":"ENSG00000092931","Gene description":"Major facilitator superfamily domain containing 11","Uniprot":["O43934"],"Chromosome":"17","Position":"76735865-76781449","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"144.8","Late spermatids":"233.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022001"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA022001":"AB_2297599"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.69e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.90e-4"}},{"Gene":"MFSD12","Gene synonym":["C19orf28","MGC20700","PP3501"],"Ensembl":"ENSG00000161091","Gene description":"Major facilitator superfamily domain containing 12","Uniprot":["Q6NUT3"],"Chromosome":"19","Position":"3538261-3574290","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Melanin biosynthesis","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"167.8","Melanocytes":"311.8","Syncytiotrophoblasts":"123.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"melanoma":"124.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"skin cancer":"647.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042149","HPA043088"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042149":"AB_2677875","HPA043088":"AB_2678308"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.66e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.61e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.34e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.70e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"}},{"Gene":"MFSD13A","Gene synonym":["bA18I14.8","C10orf77","FLJ22529","TMEM180"],"Ensembl":"ENSG00000138111","Gene description":"Major facilitator superfamily domain containing 13A","Uniprot":["Q14CX5"],"Chromosome":"10","Position":"102461395-102477045","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"29.3","Syncytiotrophoblasts":"33.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018031"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA018031":"AB_2204891"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.29e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.51e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"}},{"Gene":"MFSD14A","Gene synonym":["DKFZP564L0864","HIAT1"],"Ensembl":"ENSG00000156875","Gene description":"Major facilitator superfamily domain containing 14A","Uniprot":["Q96MC6"],"Chromosome":"1","Position":"100038095-100083377","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"131.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"31.6","Basal squamous epithelial cells":"32.7","Excitatory neurons":"35.3","Inhibitory neurons":"36.1","Oligodendrocyte precursor cells":"35.1","Oligodendrocytes":"51.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"182.4"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073127","HPA073681"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA073127":null,"HPA073681":"AB_2686625"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.08e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"}},{"Gene":"MFSD14B","Gene synonym":["FLJ14753","HIATL1"],"Ensembl":"ENSG00000148110","Gene description":"Major facilitator superfamily domain containing 14B","Uniprot":["Q5SR56"],"Chromosome":"9","Position":"94374569-94461042","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017978"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017978":"AB_2116836"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"}},{"Gene":"MFSD2A","Gene synonym":["FLJ14490","MFSD2"],"Ensembl":"ENSG00000168389","Gene description":"Major facilitator superfamily domain containing 2A","Uniprot":["Q8NA29"],"Chromosome":"1","Position":"39955112-39969968","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"96.9","liver":"162.0","skin 1":"87.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"289.6","Basal prostatic cells":"215.8","Hepatocytes":"294.2","Proximal enterocytes":"204.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"classical monocyte":"13.2","intermediate monocyte":"6.6","myeloid DC":"14.7","plasmacytoid DC":"24.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"24.3","monocytes":"13.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Keratinocyte (other)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043107"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane","Cytoplasmic bodies"],"Antibody RRID":{"HPA043107":"AB_10794387"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.22e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-4"}},{"Gene":"MFSD2B","Gene synonym":[],"Ensembl":"ENSG00000205639","Gene description":"Major facilitator superfamily domain containing 2B","Uniprot":["A6NFX1"],"Chromosome":"2","Position":"24010081-24063321","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"21","RNA tissue specific nTPM":{"bone marrow":"11.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Erythroid cells":"50.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"2.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"24","RNA blood lineage specific nTPM":{"granulocytes":"2.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"Leukemia":"2.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044145"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044145":"AB_2678833"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"}},{"Gene":"MFSD3","Gene synonym":[],"Ensembl":"ENSG00000167700","Gene description":"Major facilitator superfamily domain containing 3","Uniprot":["Q96ES6"],"Chromosome":"8","Position":"144509070-144511213","Protein class":["Predicted membrane proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056013"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA056013":"AB_2683009"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.08e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.44e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"}},{"Gene":"MFSD4A","Gene synonym":["DKFZp761N1114","FLJ25004","FLJ34577","MFSD4","UNQ3064"],"Ensembl":"ENSG00000174514","Gene description":"Major facilitator superfamily domain containing 4A","Uniprot":["Q8N468"],"Chromosome":"1","Position":"205568885-205602918","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"kidney":"66.7","stomach 1":"132.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"109.0","Distal enterocytes":"44.0","Excitatory neurons":"47.5","Gastric mucus-secreting cells":"32.2","Glandular and luminal cells":"40.8","Intestinal goblet cells":"39.4","Ionocytes":"35.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"17","RNA brain regional specific nTPM":{"amygdala":"11.4","basal ganglia":"8.4","cerebral cortex":"18.4","hippocampal formation":"14.1","white matter":"5.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"5.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Kidney - Ascending Loop of Henle cells","Skin - Eccrine sweat gland cells","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebral cortex":"59.8"},"Antibody":["HPA055407"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055407":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.54e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.59e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.27e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"}},{"Gene":"MFSD4B","Gene synonym":["KIAA1919","MGC33953"],"Ensembl":"ENSG00000173214","Gene description":"Major facilitator superfamily domain containing 4B","Uniprot":["Q5TF39"],"Chromosome":"6","Position":"111259327-111445354","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Sugar transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"73.0","Rod photoreceptor cells":"81.6","Syncytiotrophoblasts":"101.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031784"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031784":"AB_10603775"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-4"}},{"Gene":"MFSD5","Gene synonym":["HsMOT2","MGC11308"],"Ensembl":"ENSG00000182544","Gene description":"Major facilitator superfamily domain containing 5","Uniprot":["Q6N075"],"Chromosome":"12","Position":"53251251-53254406","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039773"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039773":"AB_10793920"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.43e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"}},{"Gene":"MFSD6","Gene synonym":["FLJ20160"],"Ensembl":"ENSG00000151690","Gene description":"Major facilitator superfamily domain containing 6","Uniprot":["Q6ZSS7"],"Chromosome":"2","Position":"190408355-190509205","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"84.3","Oligodendrocytes":"104.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Skin - Keratinocyte (other)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022274"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA022274":"AB_2142776"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"}},{"Gene":"MFSD6L","Gene synonym":["FLJ35773"],"Ensembl":"ENSG00000185156","Gene description":"Major facilitator superfamily domain containing 6 like","Uniprot":["Q8IWD5"],"Chromosome":"17","Position":"8797110-8799365","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"9.4","testis":"25.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Early spermatids":"114.0","Late spermatids":"63.8","Spermatocytes":"37.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"6.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023164"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023164":"AB_2142777"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.84e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"MFSD8","Gene synonym":["CLN7","MGC33302"],"Ensembl":"ENSG00000164073","Gene description":"Major facilitator superfamily domain containing 8","Uniprot":["Q8NHS3"],"Chromosome":"4","Position":"127917799-127966034","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"60.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044802"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA044802":"AB_10963221"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.21e-4"}},{"Gene":"MFSD9","Gene synonym":["MGC11332"],"Ensembl":"ENSG00000135953","Gene description":"Major facilitator superfamily domain containing 9","Uniprot":["Q8NBP5"],"Chromosome":"2","Position":"102714630-102736888","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055293","HPA061859"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":null,"Antibody RRID":{"HPA055293":"AB_2682775","HPA061859":"AB_2684627"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.38e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"}},{"Gene":"MGAM","Gene synonym":["MGA"],"Ensembl":"ENSG00000257335","Gene description":"Maltase-glucoamylase","Uniprot":["O43451"],"Chromosome":"7","Position":"141907813-142106747","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase","Multifunctional enzyme"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"25.5","intestine":"87.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Late spermatids":"159.9","Proximal enterocytes":"509.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"renal cancer":"4.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"2.3"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"13.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"102","RNA blood lineage specific nTPM":{"granulocytes":"13.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"5.3"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Neutrophils","Lung - Neutrophil_2","Skeletal muscle - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"12","RNA mouse brain regional specific nTPM":{"olfactory bulb":"2.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002270"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"310000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002270":"AB_1079366"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.16e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"}},{"Gene":"MGAM2","Gene synonym":[],"Ensembl":"ENSG00000257743","Gene description":"Maltase-glucoamylase 2 (putative)","Uniprot":["Q2M2H8"],"Chromosome":"7","Position":"142111749-142222324","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"11.8","pancreas":"4.0","salivary gland":"5.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"27.8","Late spermatids":"18.7","Mucus glandular cells":"11.0","Serous glandular cells":"7.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"colorectal cancer":"3.5","pancreatic cancer":"2.5","stomach cancer":"9.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"10.1","Gastric cancer":"5.0"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Colon - Colon enterocytes","Lung - Neutrophil_2","Skin - Eccrine sweat gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055697"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA055697":"AB_2682890"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"}},{"Gene":"MGAT1","Gene synonym":["GLCNAC-TI","GLYT1","GNT-1","GnTI","MGAT"],"Ensembl":"ENSG00000131446","Gene description":"Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase","Uniprot":["P26572"],"Chromosome":"5","Position":"180784780-180815652","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"313.6","monocytes":"275.2","Syncytiotrophoblasts":"513.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Skin - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017432"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017432":"AB_1853851"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.65e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"}},{"Gene":"MGAT3","Gene synonym":["GNT-III"],"Ensembl":"ENSG00000128268","Gene description":"Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase","Uniprot":["Q09327"],"Chromosome":"22","Position":"39457012-39492194","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"47.0","intestine":"28.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"28.7","Excitatory neurons":"24.8","Horizontal cells":"28.2","Inhibitory neurons":"26.7","Late spermatids":"26.8","Oligodendrocyte precursor cells":"20.7","Oligodendrocytes":"43.1","Proximal enterocytes":"32.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.4","eosinophil":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"60.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017598"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017598":"AB_1853853"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.04e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"}},{"Gene":"MGAT4C","Gene synonym":["HGNT-IV-H"],"Ensembl":"ENSG00000182050","Gene description":"MGAT4 family member C","Uniprot":["Q9UBM8"],"Chromosome":"12","Position":"85955666-86838904","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"3.7","pituitary gland":"3.1","testis":"4.7","thyroid gland":"6.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Astrocytes":"849.0","Excitatory neurons":"972.9","Inhibitory neurons":"1402.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"19","RNA cancer specific FPKM":{"thyroid cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"1.1","testis cancer":"1.9"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Liver - Hepatic stellate cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016418"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA016418":"AB_2732416"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"}},{"Gene":"MGAT5","Gene synonym":["GNT-V","MGAT5A"],"Ensembl":"ENSG00000152127","Gene description":"Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase","Uniprot":["Q09328"],"Chromosome":"2","Position":"134119983-134454621","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"107.8","Inhibitory neurons":"131.8","Microglial cells":"137.7","Oligodendrocyte precursor cells":"119.4","Oligodendrocytes":"467.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010919"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"440000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010919":"AB_10601864"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"}},{"Gene":"MGAT5B","Gene synonym":["FLJ25132","GnT-IX","GnT-VB"],"Ensembl":"ENSG00000167889","Gene description":"Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B","Uniprot":["Q3V5L5"],"Chromosome":"17","Position":"76868404-76950393","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"12.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"15.5","Cone photoreceptor cells":"10.3","Excitatory neurons":"25.8","Horizontal cells":"9.6","Inhibitory neurons":"21.4","Late spermatids":"9.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"2.6","melanoma":"7.1","testis cancer":"2.4"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"12.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011082"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytokinetic bridge","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Nucleoplasm","Mitotic spindle"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA011082":"AB_2668423"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"}},{"Gene":"MGLL","Gene synonym":["HU-K5","MAGL","MGL"],"Ensembl":"ENSG00000074416","Gene description":"Monoglyceride lipase","Uniprot":["Q99685"],"Chromosome":"3","Position":"127689062-128052190","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase","Serine esterase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"560.6","Alveolar cells type 1":"955.9","Suprabasal keratinocytes":"363.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"84.7","plasmacytoid DC":"89.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"dendritic cells":"89.8","granulocytes":"36.0","monocytes":"84.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Lung - Alveolar cells type 1","Pancreas - Endothelial cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011348","HPA011993","HPA011994"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA011348":"AB_2668490","HPA011993":"AB_1853914","HPA011994":"AB_1853916"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.41e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"}},{"Gene":"MGST1","Gene synonym":["GST12","MGST-I"],"Ensembl":"ENSG00000008394","Gene description":"Microsomal glutathione S-transferase 1","Uniprot":["P10620"],"Chromosome":"12","Position":"16347142-16609259","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"1096.9","adrenal gland":"1137.3","liver":"3104.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"1600.2","Basal respiratory cells":"1213.4","Hepatocytes":"4707.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"170.2","myeloid DC":"123.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"dendritic cells":"123.5","monocytes":"170.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Colon - Macrophages","Kidney - Proximal tubular cells","Skin - Sebaceous gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044840"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA044840":"AB_10965550"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.97e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"}},{"Gene":"MGST2","Gene synonym":["MGST-II"],"Ensembl":"ENSG00000085871","Gene description":"Microsomal glutathione S-transferase 2","Uniprot":["Q99735"],"Chromosome":"4","Position":"139665768-139740745","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Leukotriene biosynthesis","Lipid metabolism"],"Molecular function":["Lyase","Oxidoreductase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"393.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"459.1","Proximal enterocytes":"450.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"194.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010690","HPA010707"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA010690":null,"HPA010707":"AB_1853922"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.26e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.22e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"}},{"Gene":"MGST3","Gene synonym":["GST-III"],"Ensembl":"ENSG00000143198","Gene description":"Microsomal glutathione S-transferase 3","Uniprot":["O14880"],"Chromosome":"1","Position":"165631213-165661796","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Lyase","Oxidoreductase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"2192.5","Syncytiotrophoblasts":"2404.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053311","HPA077929"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"27000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053311":"AB_2682108","HPA077929":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"}},{"Gene":"MIA2","Gene synonym":["cTAGE-5A","cTAGE-5B","cTAGE-5C","cTAGE-5D","CTAGE5","FLJ22404","MEA6","MGEA","MGEA11","MGEA6","TALI"],"Ensembl":"ENSG00000150527","Gene description":"MIA SH3 domain ER export factor 2","Uniprot":["Q96PC5"],"Chromosome":"14","Position":"39230231-39388513","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"138.9"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Kidney - Proximal tubular cells","Skeletal muscle - Skeletal myocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000387","HPA000922","HPA054066","HPA055459"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA000387":"AB_1078582","HPA000922":"AB_1078581","HPA054066":"AB_2682368","HPA055459":"AB_2682819"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.81e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"}},{"Gene":"MIA3","Gene synonym":["FLJ39207","KIAA0268","TANGO","TANGO1","UNQ6077"],"Ensembl":"ENSG00000154305","Gene description":"MIA SH3 domain ER export factor 3","Uniprot":["Q5JRA6"],"Chromosome":"1","Position":"222618097-222668007","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["ER-Golgi transport","Exocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Diabetes mellitus","Dwarfism","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Prostatic glandular cells":"206.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055922","HPA056816"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA055922":"AB_2682971","HPA056816":"AB_2683243"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"}},{"Gene":"MICA","Gene synonym":["PERB11.1"],"Ensembl":"ENSG00000204520","Gene description":"MHC class I polypeptide-related sequence A","Uniprot":[],"Chromosome":"6","Position":"31399784-31415315","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.88e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"}},{"Gene":"MICAL2","Gene synonym":["KIAA0750"],"Ensembl":"ENSG00000133816","Gene description":"Microtubule associated monooxygenase, calponin and LIM domain containing 2","Uniprot":["O94851"],"Chromosome":"11","Position":"12094008-12359144","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Actin-binding","Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"61.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"151.6","Excitatory neurons":"190.8","Inhibitory neurons":"106.4","Late spermatids":"232.8","Peritubular cells":"112.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"8.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030437","HPA039895","HPA040438"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA030437":"AB_10601873","HPA039895":"AB_2676731","HPA040438":"AB_10672896"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.88e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.63e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"}},{"Gene":"MICAL3","Gene synonym":["KIAA0819"],"Ensembl":"ENSG00000243156","Gene description":"Microtubule associated monooxygenase, calponin and LIM domain containing 3","Uniprot":["Q7RTP6"],"Chromosome":"22","Position":"17787649-18024561","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","Exocytosis"],"Molecular function":["Actin-binding","Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"104.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"173.9","Inhibitory neurons":"160.7","Oligodendrocytes":"203.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"104.9"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"11.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"11.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000639","HPA003421","HPA034882"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Midbody ring","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Midbody ring"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA000639":"AB_10301319","HPA003421":"AB_10601134","HPA034882":"AB_2674371"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"}},{"Gene":"MICB","Gene synonym":["PERB11.2"],"Ensembl":"ENSG00000204516","Gene description":"MHC class I polypeptide-related sequence B","Uniprot":["Q29980"],"Chromosome":"6","Position":"31494881-31511124","Protein class":["Disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Cytolysis","Host-virus interaction","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"9.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"12.9","Kupffer cells":"10.7","monocytes":"12.4","NK-cells":"10.4","Plasma cells":"9.7","T-cells":"11.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064618"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA064618":"AB_2685301"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.04e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.94e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"}},{"Gene":"MICOS10","Gene synonym":["C1orf151","FLJ36999","Mic10","MINOS1","MIO10","RP5-1056L3.2"],"Ensembl":"ENSG00000173436","Gene description":"Mitochondrial contact site and cristae organizing system subunit 10","Uniprot":["Q5TGZ0"],"Chromosome":"1","Position":"19484403-19629821","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"1063.5","Proximal tubular cells":"987.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059930"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA059930":"AB_2684167"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.23e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.11e-4"}},{"Gene":"MICU1","Gene synonym":["CALC","CBARA1","EFHA3","FLJ12684"],"Ensembl":"ENSG00000107745","Gene description":"Mitochondrial calcium uptake 1","Uniprot":["Q9BPX6"],"Chromosome":"10","Position":"72367327-72626191","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Allergen"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"182.8","Inhibitory neurons":"201.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037479","HPA037480"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA037479":"AB_2675495","HPA037480":"AB_10696934"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.66e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"}},{"Gene":"MICU3","Gene synonym":["DKFZp313A0139","EFHA2"],"Ensembl":"ENSG00000155970","Gene description":"Mitochondrial calcium uptake family member 3","Uniprot":["Q86XE3"],"Chromosome":"8","Position":"17027238-17122642","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"23.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"159.1","Inhibitory neurons":"163.4","Oligodendrocyte precursor cells":"92.4","Oligodendrocytes":"133.9","Rod photoreceptor cells":"84.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"10.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024771","HPA024779"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024771":"AB_1848022","HPA024779":"AB_1848023"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"}},{"Gene":"MID1","Gene synonym":["FXY","OS","RNF59","TRIM18"],"Ensembl":"ENSG00000101871","Gene description":"Midline 1","Uniprot":["O15344"],"Chromosome":"X","Position":"10445310-10833654","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"125.3","Basal squamous epithelial cells":"67.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002878","HPA003715"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA002878":null,"HPA003715":"AB_1079384"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"}},{"Gene":"MIDN","Gene synonym":[],"Ensembl":"ENSG00000167470","Gene description":"Midnolin","Uniprot":["Q504T8"],"Chromosome":"19","Position":"1248553-1259140","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"11.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"11.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Neutrophils"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042018","HPA049432"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA042018":"AB_2677800","HPA049432":"AB_2680765"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"}},{"Gene":"MIEF1","Gene synonym":["FLJ20232","L0R8F8","MiD51","SMCR7L"],"Ensembl":"ENSG00000100335","Gene description":"Mitochondrial elongation factor 1","Uniprot":["Q9NQG6"],"Chromosome":"22","Position":"39499432-39518132","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"202.1","Late spermatids":"416.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061059"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Intermediate filaments","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA061059":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.96e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"}},{"Gene":"MIEF2","Gene synonym":["MGC23130","MiD49","SMCR7"],"Ensembl":"ENSG00000177427","Gene description":"Mitochondrial elongation factor 2","Uniprot":["Q96C03"],"Chromosome":"17","Position":"18260597-18266552","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042334"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042334":"AB_10794418"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.75e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"}},{"Gene":"MIF4GD","Gene synonym":["AD023","MGC45027","MIFD","SLIP1"],"Ensembl":"ENSG00000125457","Gene description":"MIF4G domain containing","Uniprot":["A9UHW6"],"Chromosome":"17","Position":"75266228-75271231","Protein class":["Predicted intracellular proteins"],"Biological process":["Translation regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"93.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051222"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA051222":"AB_2681393"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.70e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"}},{"Gene":"MIGA1","Gene synonym":["FAM73A","FLJ35093"],"Ensembl":"ENSG00000180488","Gene description":"Mitoguardin 1","Uniprot":["Q8NAN2"],"Chromosome":"1","Position":"77779624-77879539","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"121.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017589"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA017589":"AB_1848409"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"}},{"Gene":"MIGA2","Gene synonym":["C9orf54","FAM73B","FLJ00199","FLJ14596"],"Ensembl":"ENSG00000148343","Gene description":"Mitoguardin 2","Uniprot":["Q7L4E1"],"Chromosome":"9","Position":"129036621-129072082","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041363"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA041363":"AB_10794664"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.04e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"}},{"Gene":"MILR1","Gene synonym":["Allergin-1","C17orf60","MCA-32"],"Ensembl":"ENSG00000271605","Gene description":"Mast cell immunoglobulin like receptor 1","Uniprot":["Q7Z6M3"],"Chromosome":"17","Position":"64449037-64468643","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"25.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"65.6","Hofbauer cells":"76.8","Macrophages":"26.0","Microglial cells":"42.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"85.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"34.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014347"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014347":"AB_2732408"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.07e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"}},{"Gene":"MINAR1","Gene synonym":["KIAA1024","UBTOR"],"Ensembl":"ENSG00000169330","Gene description":"Membrane integral NOTCH2 associated receptor 1","Uniprot":["Q9UPX6"],"Chromosome":"15","Position":"79432336-79472304","Protein class":["Predicted membrane proteins"],"Biological process":["Angiogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"10.3","brain":"4.7","retina":"6.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"13.6","Muller glia cells":"23.3","Oligodendrocyte precursor cells":"6.3","Oligodendrocytes":"5.5","Serous glandular cells":"5.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011545"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA011545":"AB_1852361"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"}},{"Gene":"MINAR2","Gene synonym":["KIAA1024L"],"Ensembl":"ENSG00000186367","Gene description":"Membrane integral NOTCH2 associated receptor 2","Uniprot":["P59773"],"Chromosome":"5","Position":"129748094-129766732","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"skeletal muscle":"35.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"1.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"1.7"},"RNA tissue cell type enrichment":["Kidney - Podocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013760"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013760":"AB_1852363"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MINPP1","Gene synonym":["MIPP"],"Ensembl":"ENSG00000107789","Gene description":"Multiple inositol-polyphosphate phosphatase 1","Uniprot":["Q9UNW1"],"Chromosome":"10","Position":"87504875-87553461","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Erythroid cells":"194.8","Hepatocytes":"52.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026859"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026859":"AB_1853961"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.98e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"}},{"Gene":"MIP","Gene synonym":["AQP0","LIM1","MP26"],"Ensembl":"ENSG00000135517","Gene description":"Major intrinsic protein of lens fiber","Uniprot":["P30301"],"Chromosome":"12","Position":"56449502-56469166","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Sensory transduction","Transport","Vision"],"Molecular function":["Eye lens protein"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014940"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 1: Non-specific - Nucleosome assembly","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014940":"AB_2669122"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"}},{"Gene":"MKNK1","Gene synonym":["MNK1"],"Ensembl":"ENSG00000079277","Gene description":"MAPK interacting serine\/threonine kinase 1","Uniprot":["Q9BUB5"],"Chromosome":"1","Position":"46557407-46616843","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Translation regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"128.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"140.7","Microglial cells":"97.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB027355","CAB037310","HPA071293"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB027355":"AB_2266303","CAB037310":"AB_1854049","HPA071293":"AB_2686382"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.05e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.51e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-3"}},{"Gene":"MKNK2","Gene synonym":["GPRK7","MNK2"],"Ensembl":"ENSG00000099875","Gene description":"MAPK interacting serine\/threonine kinase 2","Uniprot":["Q9HBH9"],"Chromosome":"19","Position":"2037465-2051244","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Translation regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"475.7","tongue":"551.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"294.0","Suprabasal keratinocytes":"277.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021875","CAB037253","HPA070499"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB037253":"AB_1079401","HPA021875":"AB_1854050","HPA070499":"AB_2732157"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.86e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.01e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"}},{"Gene":"MLANA","Gene synonym":["MART1"],"Ensembl":"ENSG00000120215","Gene description":"Melan-A","Uniprot":["Q16655"],"Chromosome":"9","Position":"5890889-5910606","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"skin 1":"42.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"49","RNA single cell type specific nTPM":{"Melanocytes":"2420.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"556","RNA cancer specific FPKM":{"melanoma":"277.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"42","RNA cell line specific nTPM":{"skin cancer":"346.4"},"RNA tissue cell type enrichment":["Skin - Melanocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000057","HPA048662"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000057":"AB_442107","HPA048662":"AB_2680485"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"}},{"Gene":"MLC1","Gene synonym":["KIAA0027","LVM","MLC","VL"],"Ensembl":"ENSG00000100427","Gene description":"Modulator of VRAC current 1","Uniprot":["Q15049"],"Chromosome":"22","Position":"50059391-50085426","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"262.7","choroid plexus":"145.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"112.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"69","RNA cancer specific FPKM":{"glioma":"122.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"20.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"60.4","Myeloma":"70.5"},"RNA tissue cell type enrichment":["Liver - NK-cells (Liver)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003040"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA003040":"AB_1079387"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"}},{"Gene":"MLEC","Gene synonym":["KIAA0152"],"Ensembl":"ENSG00000110917","Gene description":"Malectin","Uniprot":["Q14165"],"Chromosome":"12","Position":"120687149-120701859","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"880000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.60e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.77e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"MLLT10","Gene synonym":["AF10"],"Ensembl":"ENSG00000078403","Gene description":"MLLT10 histone lysine methyltransferase DOT1L cofactor","Uniprot":["P55197"],"Chromosome":"10","Position":"21524646-21743630","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"93.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"198.4","Inhibitory neurons":"165.8","Spermatocytes":"221.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005736","HPA005747","HPA072790"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA005736":null,"HPA005747":"AB_1079393","HPA072790":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.75e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"}},{"Gene":"MLNR","Gene synonym":["GPR38"],"Ensembl":"ENSG00000102539","Gene description":"Motilin receptor","Uniprot":["O43193"],"Chromosome":"13","Position":"49220338-49222377","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1.3","thyroid gland":"1.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"testis cancer":"2.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070324"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":null,"Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA070324":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"MLPH","Gene synonym":["exophilin-3","l(1)-3Rk","l1Rk3","ln","Slac-2a"],"Ensembl":"ENSG00000115648","Gene description":"Melanophilin","Uniprot":["Q9BV36"],"Chromosome":"2","Position":"237485428-237555322","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"135.9","salivary gland":"122.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"250.8","Gastric mucus-secreting cells":"245.6","granulocytes":"144.9","Intestinal goblet cells":"220.9","Mucus glandular cells":"127.2","Prostatic glandular cells":"155.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014685"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014685":"AB_1853997"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.14e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"}},{"Gene":"MMADHC","Gene synonym":["C2orf25","cblD","CL25022"],"Ensembl":"ENSG00000168288","Gene description":"Metabolism of cobalamin associated D","Uniprot":["Q9H3L0"],"Chromosome":"2","Position":"149569637-149587778","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037531","HPA037532"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037531":"AB_10671628","HPA037532":"AB_2675526"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"}},{"Gene":"MMD","Gene synonym":["MMA","PAQR11"],"Ensembl":"ENSG00000108960","Gene description":"Monocyte to macrophage differentiation associated","Uniprot":["Q15546"],"Chromosome":"17","Position":"55392622-55421924","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adipose tissue":"152.2","brain":"87.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026978"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA026978":"AB_2672068"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.52e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.88e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.39e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.85e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.62e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"}},{"Gene":"MMD2","Gene synonym":["PAQR10"],"Ensembl":"ENSG00000136297","Gene description":"Monocyte to macrophage differentiation associated 2","Uniprot":["Q8IY49"],"Chromosome":"7","Position":"4905989-4959213","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"27.4","retina":"6.1","testis":"7.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Astrocytes":"245.5","Oligodendrocyte precursor cells":"116.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"59","RNA cancer specific FPKM":{"glioma":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MME","Gene synonym":["CALLA","CD10","NEP"],"Ensembl":"ENSG00000196549","Gene description":"Membrane metalloendopeptidase","Uniprot":["P08473"],"Chromosome":"3","Position":"155024124-155183704","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Disease variant","FDA approved drug targets","Neurodegeneration","Neuropathy","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"333.5","kidney":"302.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"77.6","Cytotrophoblasts":"79.6","Endometrial stromal cells":"274.1","Prostatic glandular cells":"121.5","Proximal enterocytes":"327.5","Syncytiotrophoblasts":"128.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"17.6"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"17.3","medulla oblongata":"9.3","pons":"10.9","thalamus":"4.6"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"122","RNA blood cell specific nTPM":{"neutrophil":"139.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"122","RNA blood lineage specific nTPM":{"granulocytes":"139.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Heart muscle - Fibroblasts","Kidney - Podocytes","Liver - Hepatocytes","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"28.1"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"32.3","olfactory bulb":"8.5","spinal cord":"15.9"},"Antibody":["CAB000013","HPA052583","HPA056072"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000013":"AB_563478","HPA052583":"AB_2681872","HPA056072":"AB_2683027"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"}},{"Gene":"MMEL1","Gene synonym":["MMEL2","NEPII","NL1","NL2","SEP"],"Ensembl":"ENSG00000142606","Gene description":"Membrane metalloendopeptidase like 1","Uniprot":["Q495T6"],"Chromosome":"1","Position":"2590639-2633016","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"24.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"133.8","Late spermatids":"48.7","Paneth cells":"64.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"2.0","pancreatic cancer":"1.4"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007876","HPA008205","CAB020786"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB020786":null,"HPA007876":"AB_1854012","HPA008205":"AB_1854011"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-4"}},{"Gene":"MMGT1","Gene synonym":["EMC5","TMEM32"],"Ensembl":"ENSG00000169446","Gene description":"Membrane magnesium transporter 1","Uniprot":["Q8N4V1"],"Chromosome":"X","Position":"135960588-135974029","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032037"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA032037":"AB_10670705"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.54e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.94e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"}},{"Gene":"MMP14","Gene synonym":["MT1-MMP"],"Ensembl":"ENSG00000157227","Gene description":"Matrix metallopeptidase 14","Uniprot":["P50281"],"Chromosome":"14","Position":"22836560-22849041","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"118.5","Extravillous trophoblasts":"262.6","Pancreatic endocrine cells":"121.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009918","HPA051432"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"CAB009918":"AB_2250767","HPA051432":"AB_2681484"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.48e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"}},{"Gene":"MMP15","Gene synonym":["MT2-MMP","MTMMP2","SMCP-2"],"Ensembl":"ENSG00000102996","Gene description":"Matrix metallopeptidase 15","Uniprot":["P51511"],"Chromosome":"16","Position":"58025754-58046901","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"79.0","Extravillous trophoblasts":"54.0","Proximal enterocytes":"60.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Stomach - Gastric mucous cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002611","HPA040390"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB002611":null,"HPA040390":"AB_2676956"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.54e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.08e-4"}},{"Gene":"MMP16","Gene synonym":["C8orf57","DKFZp761D112","MT3-MMP"],"Ensembl":"ENSG00000156103","Gene description":"Matrix metallopeptidase 16","Uniprot":["P51512"],"Chromosome":"8","Position":"88032011-88328025","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Collagen degradation"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"2300.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"4.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"11.5"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Lung - Fibroblast_2","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023693"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA023693":"AB_1854025"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"}},{"Gene":"MMP17","Gene synonym":["MT4-MMP"],"Ensembl":"ENSG00000198598","Gene description":"Matrix metallopeptidase 17","Uniprot":["Q9ULZ9"],"Chromosome":"12","Position":"131828393-131851783","Protein class":["Enzymes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"37.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"46.3","Inhibitory neurons":"13.9","Melanocytes":"41.8","monocytes":"13.0","Oligodendrocyte precursor cells":"25.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"melanoma":"29.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"skin cancer":"62.4"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Fibroblasts","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"}},{"Gene":"MMP23B","Gene synonym":["MIFR","MIFR-1","MMP22"],"Ensembl":"ENSG00000189409","Gene description":"Matrix metallopeptidase 23B","Uniprot":["O75900"],"Chromosome":"1","Position":"1632163-1635263","Protein class":["Enzymes","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"29.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"10.5","Fibroblasts":"17.9","Leydig cells":"12.7","NK-cells":"10.6","Peritubular cells":"22.3","Thymic epithelial cells":"41.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"11.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"11.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"2.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Prostate - Fibroblasts","Skin - Fibroblast_1","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebellum":"7.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"}},{"Gene":"MMP24","Gene synonym":["MT5-MMP"],"Ensembl":"ENSG00000125966","Gene description":"Matrix metallopeptidase 24","Uniprot":["Q9Y5R2"],"Chromosome":"20","Position":"35226690-35276998","Protein class":["Enzymes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"40.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"17.6","Excitatory neurons":"24.2","Horizontal cells":"15.4","Inhibitory neurons":"37.5","Oligodendrocyte precursor cells":"12.0","Proximal tubular cells":"13.7","Thymic epithelial cells":"20.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"11.4","testis cancer":"10.8"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"40.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"39.6"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Smooth muscle cells","Pancreas - Ductal cells","Prostate - Smooth muscle cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"cerebellum":"51.5"},"Antibody":["HPA049280","HPA078816"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Plasma membrane"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoli","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA049280":null,"HPA078816":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.17e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-4"}},{"Gene":"MMP25","Gene synonym":["MMP20","MMPL1","MT6-MMP"],"Ensembl":"ENSG00000008516","Gene description":"Matrix metallopeptidase 25","Uniprot":["Q9NPA2"],"Chromosome":"16","Position":"3046062-3060726","Protein class":["Enzymes","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"33.1","lymphoid tissue":"81.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"7.3","Langerhans cells":"3.5","Macrophages":"3.8","Schwann cells":"4.4","Serous glandular cells":"3.9","T-cells":"4.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"testis cancer":"7.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"18.3","neutrophil":"20.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"39","RNA blood lineage specific nTPM":{"granulocytes":"20.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"2.5"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2","Skeletal muscle - Neutrophils","Stomach - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025177","HPA055640"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB025177":null,"HPA055640":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.09e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"}},{"Gene":"MMS22L","Gene synonym":["C6orf167","dJ39B17.2"],"Ensembl":"ENSG00000146263","Gene description":"MMS22 like, DNA repair protein","Uniprot":["Q6ZRQ5"],"Chromosome":"6","Position":"97142161-97283217","Protein class":["Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Chromatin regulator","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"81.5","Oligodendrocytes":"49.4","Spermatocytes":"54.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Mitotic cells (Skin)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067042"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA067042":"AB_2685768"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"}},{"Gene":"MOG","Gene synonym":["BTN6","BTNL11"],"Ensembl":"ENSG00000204655","Gene description":"Myelin oligodendrocyte glycoprotein","Uniprot":["Q16653"],"Chromosome":"6","Position":"29657002-29672372","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"brain":"73.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"48","RNA single cell type specific nTPM":{"Oligodendrocytes":"445.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"45","RNA cancer specific FPKM":{"glioma":"15.1"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"73.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"white matter":"1396.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021873"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021873":"AB_1854055"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MOGAT1","Gene synonym":["DGAT2L","DGAT2L1","MGAT1"],"Ensembl":"ENSG00000124003","Gene description":"Monoacylglycerol O-acyltransferase 1","Uniprot":["Q96PD6"],"Chromosome":"2","Position":"222671658-222709930","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Glycerol metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"gallbladder":"16.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"7.9","Breast glandular cells":"7.5","Cholangiocytes":"9.6","Endometrial ciliated cells":"3.2","Glandular and luminal cells":"4.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"0.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Skin - Sebaceous gland cells","Stomach - Chief cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049944","HPA076308"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA049944":"AB_2680964","HPA076308":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"MOGAT2","Gene synonym":["DGAT2L5","FLJ22644","MGAT2"],"Ensembl":"ENSG00000166391","Gene description":"Monoacylglycerol O-acyltransferase 2","Uniprot":["Q3SYC2"],"Chromosome":"11","Position":"75717838-75732958","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Glycerol metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"intestine":"48.2","liver":"25.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"60.4","Hepatocytes":"68.7","Intestinal goblet cells":"32.0","Paneth cells":"21.6","Proximal enterocytes":"149.6","Undifferentiated cells":"21.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"6.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.1","Gastric cancer":"1.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Prostate - Prostate glandular cells","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028834"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA028834":"AB_10601865"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-3"}},{"Gene":"MOGAT3","Gene synonym":["DC7","DGAT2L2","MGAT3"],"Ensembl":"ENSG00000106384","Gene description":"Monoacylglycerol O-acyltransferase 3","Uniprot":["Q86VF5"],"Chromosome":"7","Position":"101195007-101201038","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Glycerol metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"intestine":"24.4","liver":"18.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal enterocytes":"75.4","Paneth cells":"41.6","Proximal enterocytes":"91.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"11.0","liver cancer":"11.1","stomach cancer":"3.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"5.8","liver cancer":"3.8"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011940"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011940":"AB_1854057"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"}},{"Gene":"MOGS","Gene synonym":["CWH41","DER7","GCS1"],"Ensembl":"ENSG00000115275","Gene description":"Mannosyl-oligosaccharide glucosidase","Uniprot":["Q13724"],"Chromosome":"2","Position":"74461057-74465410","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"242.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011322","HPA011969"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA011322":"AB_2668483","HPA011969":"AB_1849579"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.33e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.34e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.79e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-3"}},{"Gene":"MOSMO","Gene synonym":["ATTHOG","BC030336","C16orf52"],"Ensembl":"ENSG00000185716","Gene description":"Modulator of smoothened","Uniprot":["Q8NHV5"],"Chromosome":"16","Position":"22007638-22087534","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"145.9","Inhibitory neurons":"104.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"}},{"Gene":"MOSPD1","Gene synonym":["dJ473B4"],"Ensembl":"ENSG00000101928","Gene description":"Motile sperm domain containing 1","Uniprot":["Q9UJG1"],"Chromosome":"X","Position":"134887632-134915257","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"78.5","Early spermatids":"89.7","Endometrial ciliated cells":"85.8","Late spermatids":"71.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031158"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA031158":"AB_10603874"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"}},{"Gene":"MOSPD2","Gene synonym":["MGC26706"],"Ensembl":"ENSG00000130150","Gene description":"Motile sperm domain containing 2","Uniprot":["Q8NHP6"],"Chromosome":"X","Position":"14873421-14922327","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Chemotaxis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"48.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"118.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"53.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"53.4","monocytes":"15.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003334"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA003334":"AB_2146004"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.91e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"}},{"Gene":"MOSPD3","Gene synonym":["CDS3","NET30"],"Ensembl":"ENSG00000106330","Gene description":"Motile sperm domain containing 3","Uniprot":["O75425"],"Chromosome":"7","Position":"100612102-100615384","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Late spermatids":"1470.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041137","HPA048240"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041137":"AB_10803996","HPA048240":"AB_2680325"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"}},{"Gene":"MOXD1","Gene synonym":["dJ248E1.1","DKFZP564G202","MOX"],"Ensembl":"ENSG00000079931","Gene description":"Monooxygenase DBH like 1","Uniprot":["Q6UVY6"],"Chromosome":"6","Position":"132296055-132401475","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"64.2","smooth muscle":"78.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"89.8","Basal squamous epithelial cells":"80.4","Early spermatids":"82.8","Endometrial stromal cells":"53.9","Excitatory neurons":"35.6","Oligodendrocyte precursor cells":"32.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"33","RNA blood cell specific nTPM":{"memory B-cell":"3.1","naive B-cell":"1.7","plasmacytoid DC":"5.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"41","RNA blood lineage specific nTPM":{"B-cells":"3.1","dendritic cells":"5.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"64.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Colon - Enteric glia cells","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Stomach - Fibroblasts","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035740"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035740":"AB_10610141"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.09e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.72e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"}},{"Gene":"MPC1","Gene synonym":["BRP44L","CGI-129","dJ68L15.3","SLC54A1"],"Ensembl":"ENSG00000060762","Gene description":"Mitochondrial pyruvate carrier 1","Uniprot":["Q9Y5U8"],"Chromosome":"6","Position":"166364919-166383013","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"739.7","tongue":"559.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1280.7","Distal tubular cells":"1296.8","Proximal tubular cells":"522.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045119","HPA055790"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA045119":"AB_10960421","HPA055790":"AB_2682923"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.45e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.79e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"}},{"Gene":"MPC1L","Gene synonym":["SLC54A3"],"Ensembl":"ENSG00000238205","Gene description":"Mitochondrial pyruvate carrier 1 like","Uniprot":["P0DKB6"],"Chromosome":"X","Position":"40623566-40624136","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"59","RNA tissue specific nTPM":{"testis":"18.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Early spermatids":"156.1","Late spermatids":"418.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"testis cancer":"3.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-4"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MPDU1","Gene synonym":["CDGIf","Lec35","PQLC5","SL15","SLC66A5"],"Ensembl":"ENSG00000129255","Gene description":"Mannose-P-dolichol utilization defect 1","Uniprot":["O75352"],"Chromosome":"17","Position":"7583529-7592789","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"163.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014845"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA014845":"AB_1854072"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"}},{"Gene":"MPEG1","Gene synonym":["MPG1"],"Ensembl":"ENSG00000197629","Gene description":"Macrophage expressed 1","Uniprot":["Q2M385"],"Chromosome":"11","Position":"59208510-59212927","Protein class":["Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Antibiotic","Antimicrobial"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"207.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"dendritic cells":"329.5","Hofbauer cells":"104.2","Kupffer cells":"355.0","Macrophages":"210.1","monocytes":"236.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"290.5","intermediate monocyte":"209.9","myeloid DC":"144.7","non-classical monocyte":"245.2","plasmacytoid DC":"204.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"204.9","monocytes":"290.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"187","RNA cell line specific nTPM":{"Leukemia":"11.9","lymphoma":"27.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046801"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046801":"AB_2679814"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"}},{"Gene":"MPHOSPH10","Gene synonym":["CT90","MPP10","MPP10P","PPP1R106"],"Ensembl":"ENSG00000124383","Gene description":"M-phase phosphoprotein 10","Uniprot":["O00566"],"Chromosome":"2","Position":"71130632-71150101","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ribosome biogenesis","rRNA processing"],"Molecular function":["Ribonucleoprotein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035059","HPA035060","HPA049907"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoli","Nucleoli rim","Mitotic chromosome"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Mitotic chromosome"],"Antibody RRID":{"HPA035059":"AB_2674436","HPA035060":"AB_10601875","HPA049907":"AB_2680947"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.89e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"}},{"Gene":"MPI","Gene synonym":[],"Ensembl":"ENSG00000178802","Gene description":"Mannose phosphate isomerase","Uniprot":["P34949"],"Chromosome":"15","Position":"74890005-74902219","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"74.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007200"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"350000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA007200":"AB_1854079"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.39e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"}},{"Gene":"MPIG6B","Gene synonym":["C6orf25","G6b","G6b-B","NG31"],"Ensembl":"ENSG00000204420","Gene description":"Megakaryocyte and platelet inhibitory receptor G6b","Uniprot":["O95866"],"Chromosome":"6","Position":"31718594-31726714","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Heparin-binding","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"4.8","skin 1":"8.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"12.1","Early spermatids":"4.2","Erythroid cells":"9.5","granulocytes":"22.3","Late spermatids":"12.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"1.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054404","HPA073017"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"330000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Endoplasmic reticulum","Plasma membrane","Cytosol"],"Antibody RRID":{"HPA054404":null,"HPA073017":"AB_2686566"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"}},{"Gene":"MPL","Gene synonym":["CD110","THPOR","TPOR"],"Ensembl":"ENSG00000117400","Gene description":"MPL proto-oncogene, thrombopoietin receptor","Uniprot":["P40238"],"Chromosome":"1","Position":"43337818-43354466","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"2.0","Erythroid cells":"2.3","Excitatory neurons":"2.0","Granulosa cells":"2.0","Rod photoreceptor cells":"2.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Leukemia":"4.8"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"1.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007619"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"HPA007619":"AB_1854080"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"}},{"Gene":"MPPE1","Gene synonym":["Cdc1","PGAP5"],"Ensembl":"ENSG00000154889","Gene description":"Metallophosphoesterase 1","Uniprot":["Q53F39"],"Chromosome":"18","Position":"11882622-11908366","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","GPI-anchor biosynthesis","Transport"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"eosinophil":"100.8","neutrophil":"293.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"293.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012639"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA012639":"AB_1854088"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.45e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"}},{"Gene":"MPV17","Gene synonym":["SYM1"],"Ensembl":"ENSG00000115204","Gene description":"Mitochondrial inner membrane protein MPV17","Uniprot":["P39210"],"Chromosome":"2","Position":"27309492-27325680","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"}},{"Gene":"MPZ","Gene synonym":["CMT1","CMT1B","CMT2I","CMT2J","HMSNIB","P0"],"Ensembl":"ENSG00000158887","Gene description":"Myelin protein zero","Uniprot":["P25189"],"Chromosome":"1","Position":"161304735-161309968","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Deafness","Dejerine-Sottas syndrome","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Schwann cells":"561.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"melanoma":"83.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Brain cancer":"20.8","skin cancer":"78.0"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"olfactory bulb":"2.9","pons and medulla":"1.3"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"10","RNA pig brain regional specific nTPM":{"spinal cord":"2142.4"},"Antibody":["HPA068925"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA068925":"AB_2732123"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"}},{"Gene":"MPZL1","Gene synonym":["FLJ21047","PZR"],"Ensembl":"ENSG00000197965","Gene description":"Myelin protein zero like 1","Uniprot":["O95297"],"Chromosome":"1","Position":"167721192-167791919","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"183.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"183.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026966","HPA063538"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA026966":"AB_10600931","HPA063538":"AB_2685034"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.27e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.98e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.99e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.08e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"}},{"Gene":"MPZL2","Gene synonym":["EVA","EVA1"],"Ensembl":"ENSG00000149573","Gene description":"Myelin protein zero like 2","Uniprot":["O60487"],"Chromosome":"11","Position":"118253416-118264536","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"222.5","urinary bladder":"155.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"294.4","Basal respiratory cells":"269.4","Glandular and luminal cells":"182.6","Squamous epithelial cells":"371.0","Suprabasal keratinocytes":"444.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"11.6","intermediate monocyte":"9.2","myeloid DC":"17.0","neutrophil":"13.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"17.0","granulocytes":"13.2","monocytes":"11.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Kidney - Endothelial cells","Lung - Alveolar cells type 2","Skeletal muscle - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"spinal cord":"38.8"},"Antibody":["HPA060740"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA060740":"AB_2684352"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"}},{"Gene":"MPZL3","Gene synonym":[],"Ensembl":"ENSG00000160588","Gene description":"Myelin protein zero like 3","Uniprot":["Q6UWV2"],"Chromosome":"11","Position":"118226690-118252365","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"33.3","skin 1":"30.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"34.9","Respiratory ciliated cells":"37.4","Suprabasal keratinocytes":"41.6","T-cells":"42.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"44.3","eosinophil":"99.4","MAIT T-cell":"28.9","neutrophil":"87.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"99.4","T-cells":"28.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029116"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA029116":"AB_10610142"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.98e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.64e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"}},{"Gene":"MR1","Gene synonym":["HLALS"],"Ensembl":"ENSG00000153029","Gene description":"Major histocompatibility complex, class I-related","Uniprot":["Q95460"],"Chromosome":"1","Position":"181033425-181061938","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Lung - Macrophages","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048304"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA048304":"AB_2680347"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"}},{"Gene":"MRAP","Gene synonym":["B27","C21orf61","FALP"],"Ensembl":"ENSG00000170262","Gene description":"Melanocortin 2 receptor accessory protein","Uniprot":["Q8TCY5"],"Chromosome":"21","Position":"32291813-32314784","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"27","RNA tissue specific nTPM":{"adipose tissue":"75.6","adrenal gland":"166.5","breast":"44.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"19.7","Granulosa cells":"45.5","Horizontal cells":"12.2","Late spermatids":"6.0","Sertoli cells":"8.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011024","HPA011093"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA011024":"AB_10599292","HPA011093":"AB_10600889"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"}},{"Gene":"MRAP2","Gene synonym":["bA51G5.2","C6orf117"],"Ensembl":"ENSG00000135324","Gene description":"Melanocortin 2 receptor accessory protein 2","Uniprot":["Q96G30"],"Chromosome":"6","Position":"84033772-84090881","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"20.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"13.8","Excitatory neurons":"55.7","Gastric mucus-secreting cells":"15.5","Inhibitory neurons":"32.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"5.5"},"RNA tissue cell type enrichment":["Adipose visceral - Smooth muscle cells","Pancreas - Alpha cells","Pancreas - Beta cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.66e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"}},{"Gene":"MRC1","Gene synonym":["bA541I19.1","CD206","CLEC13D","CLEC13DL","MRC1L1"],"Ensembl":"ENSG00000260314","Gene description":"Mannose receptor C-type 1","Uniprot":["P22897"],"Chromosome":"10","Position":"17809348-17911164","Protein class":["CD markers","FDA approved drug targets","Plasma proteins","Predicted membrane proteins"],"Biological process":["Endocytosis","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"122.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"125.9","Hofbauer cells":"159.5","Kupffer cells":"137.6","Langerhans cells":"208.6","Macrophages":"432.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"myeloid DC":"4.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"dendritic cells":"4.8"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Rhabdoid":"8.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004114","HPA045134","CAB068203"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB068203":"AB_2665652","HPA004114":"AB_1846270","HPA045134":"AB_2679228"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"}},{"Gene":"MRC2","Gene synonym":["CD280","CLEC13E","ENDO180","KIAA0709"],"Ensembl":"ENSG00000011028","Gene description":"Mannose receptor C type 2","Uniprot":["Q9UBG0"],"Chromosome":"17","Position":"62627670-62693597","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"59.8","Fibroblasts":"123.2","Late spermatids":"91.7","Leydig cells":"73.3","Peritubular cells":"96.6","Theca cells":"75.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"100.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Liver - Hepatic stellate cells","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041991"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"36000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041991":"AB_10794166"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.68e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.94e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"}},{"Gene":"MRGPRD","Gene synonym":["mrgD"],"Ensembl":"ENSG00000172938","Gene description":"MAS related GPR family member D","Uniprot":["Q8TDS7"],"Chromosome":"11","Position":"68980021-68980986","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031346"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031346":"AB_10602710"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MRGPRE","Gene synonym":["GPR167","mrgE"],"Ensembl":"ENSG00000184350","Gene description":"MAS related GPR family member E","Uniprot":["Q86SM8"],"Chromosome":"11","Position":"3225030-3232417","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"37","RNA tissue specific nTPM":{"brain":"27.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.1","Erythroid cells":"1.1","Horizontal cells":"2.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"0.9"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"medulla oblongata":"27.9","pons":"26.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046556"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046556":"AB_10961404"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"MRGPRF","Gene synonym":["GPR140","GPR168","MGC21621","mrgF"],"Ensembl":"ENSG00000172935","Gene description":"MAS related GPR family member F","Uniprot":["Q96AM1"],"Chromosome":"11","Position":"69004395-69013382","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"171.2","intestine":"159.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"29.1","Leydig cells":"67.4","Peritubular cells":"99.4","Smooth muscle cells":"78.2","Thymic epithelial cells":"31.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"6.0","Sarcoma":"6.0"},"RNA tissue cell type enrichment":["Breast - Smooth muscle cells","Colon - Smooth muscle cells","Prostate - Smooth muscle cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebellum":"14.8"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"4.8"},"Antibody":["HPA028811"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nuclear membrane","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA028811":"AB_10603875"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-3"}},{"Gene":"MRGPRG","Gene synonym":["GPR169","mrgG"],"Ensembl":"ENSG00000182170","Gene description":"MAS related GPR family member G","Uniprot":["Q86SM5"],"Chromosome":"11","Position":"3217944-3218813","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"29","RNA cell line specific nTPM":{"breast cancer":"2.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058909"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058909":"AB_2683852"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MRGPRX1","Gene synonym":["MRGX1"],"Ensembl":"ENSG00000170255","Gene description":"MAS related GPR family member X1","Uniprot":["Q96LB2"],"Chromosome":"11","Position":"18933813-18939507","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Acute phase"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"18","RNA cell line specific nTPM":{"Rhabdoid":"50.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MRGPRX2","Gene synonym":["MRGX2"],"Ensembl":"ENSG00000183695","Gene description":"MAS related GPR family member X2","Uniprot":["Q96LB1"],"Chromosome":"11","Position":"19054455-19060717","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"1.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"granulocytes":"16.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Colon - Mast cells","Skin - Mast cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055220"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055220":"AB_2682743"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"MRGPRX3","Gene synonym":["MRGX3"],"Ensembl":"ENSG00000179826","Gene description":"MAS related GPR family member X3","Uniprot":["Q96LB0"],"Chromosome":"11","Position":"18120955-18138488","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"2.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Basal respiratory cells":"48.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"head and neck cancer":"1.3","melanoma":"2.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"skin cancer":"11.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MRGPRX4","Gene synonym":["MRGX4"],"Ensembl":"ENSG00000179817","Gene description":"MAS related GPR family member X4","Uniprot":["Q96LA9"],"Chromosome":"11","Position":"18172837-18174280","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"melanoma":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"skin cancer":"2.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MRLN","Gene synonym":["Linc-RAM","LINC00948","M1","MLN","MUSER1"],"Ensembl":"ENSG00000227877","Gene description":"Myoregulin","Uniprot":["P0DMT0"],"Chromosome":"10","Position":"59736692-59756041","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"skeletal muscle":"269.3","tongue":"147.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"91.6","Respiratory ciliated cells":"26.9","Rod photoreceptor cells":"27.6","Skeletal myocytes":"93.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"1.4"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"4.5"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Lung - Respiratory ciliated cells","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"cerebellum":"21.6"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"}},{"Gene":"MRPL22","Gene synonym":["HSPC158","MRP-L25","RPML25"],"Ensembl":"ENSG00000082515","Gene description":"Mitochondrial ribosomal protein L22","Uniprot":["Q9NWU5"],"Chromosome":"5","Position":"154941073-154969411","Protein class":["Predicted intracellular proteins","Ribosomal proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"348.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047063"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA047063":"AB_2679919"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"}},{"Gene":"MRPL3","Gene synonym":["MRL3","RPML3"],"Ensembl":"ENSG00000114686","Gene description":"Mitochondrial ribosomal protein L3","Uniprot":["P09001"],"Chromosome":"3","Position":"131462212-131502983","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Ribosomal proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043665","HPA060132"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043665":"AB_2678606","HPA060132":"AB_2684209"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.33e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.51e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"}},{"Gene":"MRPL37","Gene synonym":["MRP-L2","RPML2"],"Ensembl":"ENSG00000116221","Gene description":"Mitochondrial ribosomal protein L37","Uniprot":["Q9BZE1"],"Chromosome":"1","Position":"54184041-54225464","Protein class":["Predicted intracellular proteins","Ribosomal proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025767","HPA025826","HPA025951"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA025767":"AB_1854105","HPA025826":"AB_1854106","HPA025951":"AB_1854107"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.99e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.45e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.25e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"}},{"Gene":"MRPS28","Gene synonym":["HSPC007","MRP-S28","MRPS35"],"Ensembl":"ENSG00000147586","Gene description":"Mitochondrial ribosomal protein S28","Uniprot":["Q9Y2Q9"],"Chromosome":"8","Position":"79918717-80030289","Protein class":["Human disease related genes","Predicted intracellular proteins","Ribosomal proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"158.6","Proximal tubular cells":"146.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027202"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA027202":"AB_1854126"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.20e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"}},{"Gene":"MRS2","Gene synonym":["MRS2L"],"Ensembl":"ENSG00000124532","Gene description":"Magnesium transporter MRS2","Uniprot":["Q9HD23"],"Chromosome":"6","Position":"24402908-24426194","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017642"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017642":"AB_2669628"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.32e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.14e-11"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.03e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"}},{"Gene":"MS4A1","Gene synonym":["B1","Bp35","CD20","MS4A2"],"Ensembl":"ENSG00000156738","Gene description":"Membrane spanning 4-domains A1","Uniprot":["P11836"],"Chromosome":"11","Position":"60455846-60470752","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["B-cell activation"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"673.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"55","RNA single cell type specific nTPM":{"B-cells":"982.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"96","RNA blood cell specific nTPM":{"memory B-cell":"625.4","naive B-cell":"627.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"96","RNA blood lineage specific nTPM":{"B-cells":"627.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"lymphoma":"350.5"},"RNA tissue cell type enrichment":["Breast - T-cells","Lung - B-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000015","HPA014341","HPA014391"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB000015":"AB_2282030","HPA014341":"AB_1846265","HPA014391":"AB_1846264"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.34e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"}},{"Gene":"MS4A10","Gene synonym":["CD20L7","MS4A9"],"Ensembl":"ENSG00000172689","Gene description":"Membrane spanning 4-domains A10","Uniprot":["Q96PG2"],"Chromosome":"11","Position":"60785333-60801305","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"96","RNA tissue specific nTPM":{"intestine":"85.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"39","RNA single cell type specific nTPM":{"Proximal enterocytes":"313.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014778"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014778":"AB_2669089"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-3"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MS4A12","Gene synonym":["FLJ20217","Ms4a10"],"Ensembl":"ENSG00000071203","Gene description":"Membrane spanning 4-domains A12","Uniprot":["Q9NXJ0"],"Chromosome":"11","Position":"60492778-60507430","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"intestine":"254.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Distal enterocytes":"778.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"colorectal cancer":"6.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048616","HPA057657"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Endoplasmic reticulum","Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoli","Endoplasmic reticulum","Golgi apparatus"],"Antibody RRID":{"HPA048616":null,"HPA057657":"AB_2683491"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"MS4A13","Gene synonym":[],"Ensembl":"ENSG00000204979","Gene description":"Membrane spanning 4-domains A13","Uniprot":["Q5J8X5"],"Chromosome":"11","Position":"60515392-60542721","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"35","RNA tissue specific nTPM":{"testis":"3.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"27.9","Late spermatids":"49.4","Spermatocytes":"9.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045017","HPA063626"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045017":"AB_10962976","HPA063626":"AB_2685065"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MS4A14","Gene synonym":["DKFZp434H092","FLJ32856","MS4A16","NYD-SP21"],"Ensembl":"ENSG00000166928","Gene description":"Membrane spanning 4-domains A14","Uniprot":["Q96JA4"],"Chromosome":"11","Position":"60378530-60417756","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"73.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"26","RNA single cell type specific nTPM":{"Early spermatids":"248.1","Late spermatids":"680.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"5.5","non-classical monocyte":"8.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"8.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058973"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA058973":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"}},{"Gene":"MS4A15","Gene synonym":[],"Ensembl":"ENSG00000166961","Gene description":"Membrane spanning 4-domains A15","Uniprot":["Q8N5U1"],"Chromosome":"11","Position":"60756867-60776733","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"lung":"43.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Alveolar cells type 1":"23.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"6.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"3.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"T-cells":"3.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"2.6","lung cancer":"3.0","Myeloma":"3.3"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"28","RNA mouse brain regional specific nTPM":{"olfactory bulb":"166.8"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"26","RNA pig brain regional specific nTPM":{"olfactory bulb":"20.2"},"Antibody":["HPA054563"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA054563":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"}},{"Gene":"MS4A18","Gene synonym":[],"Ensembl":"ENSG00000214782","Gene description":"Membrane spanning 4-domains A18","Uniprot":["Q3C1V0"],"Chromosome":"11","Position":"60729304-60744212","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"breast":"7.7","intestine":"23.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"5.1","Late spermatids":"6.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045121"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045121":"AB_10969456"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MS4A2","Gene synonym":["APY","FCER1B","IGER","MS4A1"],"Ensembl":"ENSG00000149534","Gene description":"Membrane spanning 4-domains A2","Uniprot":["Q01362"],"Chromosome":"11","Position":"60088261-60098467","Protein class":["FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["IgE-binding protein","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"12.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"23","RNA single cell type specific nTPM":{"granulocytes":"963.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"908","RNA blood cell specific nTPM":{"basophil":"275.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"1467","RNA blood lineage specific nTPM":{"granulocytes":"275.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Leukemia":"1.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Adipose visceral - Mast cells","Colon - Mast cells","Kidney - T-cells","Lung - Mast cells","Skin - Mast cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"15.3"},"Antibody":["HPA059967"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059967":"AB_2684183"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"}},{"Gene":"MS4A3","Gene synonym":["CD20L","HTM4"],"Ensembl":"ENSG00000149516","Gene description":"Membrane spanning 4-domains A3","Uniprot":["Q96HJ5"],"Chromosome":"11","Position":"60056587-60071115","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"93","RNA tissue specific nTPM":{"bone marrow":"420.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"15.9","granulocytes":"9.2","Late spermatids":"3.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"1478","RNA blood cell specific nTPM":{"basophil":"2686.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4507","RNA blood lineage specific nTPM":{"granulocytes":"2686.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"674","RNA cell line specific nTPM":{"Leukemia":"67.3"},"RNA tissue cell type enrichment":["Lung - Neutrophil_1"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019210"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA019210":"AB_1854134"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MS4A4A","Gene synonym":["CD20L1","MS4A4","MS4A7"],"Ensembl":"ENSG00000110079","Gene description":"Membrane spanning 4-domains A4A","Uniprot":["Q96JQ5"],"Chromosome":"11","Position":"60185657-60318080","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"63.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hofbauer cells":"366.6","Kupffer cells":"185.7","Macrophages":"320.3","monocytes":"107.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"intermediate monocyte":"61.2","myeloid DC":"27.6","non-classical monocyte":"82.9","plasmacytoid DC":"27.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"30","RNA blood lineage specific nTPM":{"dendritic cells":"27.7","monocytes":"82.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"11.5","Myeloma":"11.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029323"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029323":"AB_10601866"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"}},{"Gene":"MS4A4E","Gene synonym":[],"Ensembl":"ENSG00000214787","Gene description":"Membrane spanning 4-domains A4E","Uniprot":["Q96PG1"],"Chromosome":"11","Position":"60200270-60243137","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"20.6","Kupffer cells":"6.3","Macrophages":"15.8","monocytes":"5.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"17.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"17.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Macrophages","Pancreas - Macrophages","Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040075"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040075":"AB_10793915"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"}},{"Gene":"MS4A5","Gene synonym":["CD20L2"],"Ensembl":"ENSG00000166930","Gene description":"Membrane spanning 4-domains A5","Uniprot":["Q9H3V2"],"Chromosome":"11","Position":"60429572-60455214","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"167","RNA tissue specific nTPM":{"testis":"44.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"76","RNA single cell type specific nTPM":{"Early spermatids":"618.5","Late spermatids":"1045.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043732"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043732":"AB_10959759"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MS4A6A","Gene synonym":["CD20L3","MS4A6"],"Ensembl":"ENSG00000110077","Gene description":"Membrane spanning 4-domains A6A","Uniprot":["Q9H2W1"],"Chromosome":"11","Position":"60172014-60184666","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"dendritic cells":"427.6","Hofbauer cells":"531.2","Kupffer cells":"705.2","Langerhans cells":"553.8","Macrophages":"755.6","monocytes":"268.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"406.4","classical monocyte":"1095.3","intermediate monocyte":"345.6","myeloid DC":"638.8","plasmacytoid DC":"454.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"74","RNA blood lineage specific nTPM":{"dendritic cells":"638.8","granulocytes":"406.4","monocytes":"1095.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"Leukemia":"17.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011391","HPA076623"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA011391":"AB_10603876","HPA076623":"AB_2686809"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.33e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"}},{"Gene":"MS4A6E","Gene synonym":[],"Ensembl":"ENSG00000166926","Gene description":"Membrane spanning 4-domains A6E","Uniprot":["Q96DS6"],"Chromosome":"11","Position":"60334831-60396596","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"testis":"35.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"97","RNA single cell type specific nTPM":{"Early spermatids":"1003.5","Late spermatids":"397.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076623"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA076623":"AB_2686809"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"MS4A7","Gene synonym":["CD20L4","CFFM4","MS4A8"],"Ensembl":"ENSG00000166927","Gene description":"Membrane spanning 4-domains A7","Uniprot":["Q9GZW8"],"Chromosome":"11","Position":"60378485-60395951","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"196.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hofbauer cells":"372.7","Kupffer cells":"305.4","Macrophages":"613.9","monocytes":"1048.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"intermediate monocyte":"747.4","non-classical monocyte":"1486.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"monocytes":"1486.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"7.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017418","CAB026387"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026387":null,"HPA017418":"AB_1854137"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"}},{"Gene":"MS4A8","Gene synonym":["CD20L5","MS4A4","MS4A8B"],"Ensembl":"ENSG00000166959","Gene description":"Membrane spanning 4-domains A8","Uniprot":["Q9BY19"],"Chromosome":"11","Position":"60699585-60715807","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"129.7","intestine":"197.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"387.2","Enteroendocrine cells":"328.4","Proximal enterocytes":"697.3","Respiratory ciliated cells":"262.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"14.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"lung cancer":"12.1"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Respiratory ciliated cells","Skeletal muscle - Skeletal myocytes","Stomach - Gastric enteroendocrine cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007319"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007319":"AB_1854138"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"}},{"Gene":"MSANTD3-TMEFF1","Gene synonym":["C9orf30-TMEFF1"],"Ensembl":"ENSG00000251349","Gene description":"MSANTD3-TMEFF1 readthrough","Uniprot":[],"Chromosome":"9","Position":"100442271-100577636","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"47.4","choroid plexus":"16.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1.9","Excitatory neurons":"11.8","Inhibitory neurons":"9.4","Microglial cells":"1.8","Oligodendrocyte precursor cells":"2.9","Oligodendrocytes":"4.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"38.6","testis cancer":"70.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"}},{"Gene":"MSH5","Gene synonym":["G7"],"Ensembl":"ENSG00000204410","Gene description":"MutS homolog 5","Uniprot":["O43196"],"Chromosome":"6","Position":"31739677-31762676","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Meiosis"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant","Premature ovarian failure"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"14.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"7.6","Gastric mucus-secreting cells":"8.3","Plasma cells":"6.0","Rod photoreceptor cells":"7.4","Spermatocytes":"10.0","Squamous epithelial cells":"5.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"3.4"},"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078319"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA078319":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-4"}},{"Gene":"MSLN","Gene synonym":["CAK1","MPF"],"Ensembl":"ENSG00000102854","Gene description":"Mesothelin","Uniprot":["Q13421"],"Chromosome":"16","Position":"760734-768865","Protein class":["Cancer-related genes","Disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"93.4","fallopian tube":"278.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"348.2","Ionocytes":"384.4","Paneth cells":"201.7","Thymic epithelial cells":"771.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"343.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"5.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"39","RNA blood lineage specific nTPM":{"dendritic cells":"5.9","monocytes":"1.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"125.2","pancreatic cancer":"99.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Pancreas - Ductal cells","Prostate - Urothelial cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"9","RNA pig brain regional specific nTPM":{"spinal cord":"1.7"},"Antibody":["CAB002216","HPA017172"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB002216":"AB_563874","HPA017172":"AB_1853819"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.66e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"}},{"Gene":"MSLNL","Gene synonym":["C16orf37","MPFL"],"Ensembl":"ENSG00000162006","Gene description":"Mesothelin like","Uniprot":["Q96KJ4"],"Chromosome":"16","Position":"769428-783370","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"2.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"3.7","pancreatic cancer":"2.5"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MSMO1","Gene synonym":["DESP4","ERG25","SC4MOL"],"Ensembl":"ENSG00000052802","Gene description":"Methylsterol monooxygenase 1","Uniprot":["Q15800"],"Chromosome":"4","Position":"165327667-165343164","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"575.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"418.6","Hepatocytes":"471.9","Kupffer cells":"264.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055073","HPA056127"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA055073":null,"HPA056127":"AB_2683045"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.97e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"}},{"Gene":"MSR1","Gene synonym":["CD204","SCARA1","SR-A","SR-AI","SR-AII","SR-AIII"],"Ensembl":"ENSG00000038945","Gene description":"Macrophage scavenger receptor 1","Uniprot":["P21757"],"Chromosome":"8","Position":"16107878-16567490","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lung":"120.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hofbauer cells":"124.3","Kupffer cells":"81.6","Langerhans cells":"98.4","Macrophages":"193.1","monocytes":"120.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"16.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"16.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000272","CAB032491"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"67000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB032491":"AB_672722","HPA000272":"AB_1846269"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"}},{"Gene":"MST1R","Gene synonym":["CD136","CDw136","PTK8","RON","SEA"],"Ensembl":"ENSG00000164078","Gene description":"Macrophage stimulating 1 receptor","Uniprot":["Q04912"],"Chromosome":"3","Position":"49887002-49903873","Protein class":["CD markers","Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"62.3","stomach 1":"42.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"26.0","Distal enterocytes":"29.2","Gastric mucus-secreting cells":"93.0","Intestinal goblet cells":"25.7","Proximal enterocytes":"22.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"52.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Prostate - Urothelial cells","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007657","HPA008180","CAB008972"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB008972":null,"HPA007657":"AB_1079292","HPA008180":"AB_1079291"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-5"}},{"Gene":"MT-ATP6","Gene synonym":["ATP6","ATPase-6","MTATP6","RP","Su6m"],"Ensembl":"ENSG00000198899","Gene description":"Mitochondrially encoded ATP synthase membrane subunit 6","Uniprot":["P00846"],"Chromosome":"MT","Position":"8527-9207","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["ATP synthesis","Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant","Leber hereditary optic neuropathy","Leigh syndrome","Neuropathy","Primary mitochondrial disease","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"240231.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"68183.5","Cardiomyocytes":"49112.5","Cone photoreceptor cells":"42181.9","Horizontal cells":"36532.8","Rod photoreceptor cells":"54767.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"15099.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"15099.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.79e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.64e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-3"}},{"Gene":"MT-ATP8","Gene synonym":["A6L","ATP8","MTATP8"],"Ensembl":"ENSG00000228253","Gene description":"Mitochondrially encoded ATP synthase membrane subunit 8","Uniprot":["P03928"],"Chromosome":"MT","Position":"8366-8572","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["ATP synthesis","Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"350376.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"2595.9","Cardiomyocytes":"10320.6","Gastric mucus-secreting cells":"2250.1","Squamous epithelial cells":"1920.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"10572.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"10572.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.56e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"}},{"Gene":"MT-CO1","Gene synonym":["COI","COX1","MTCO1"],"Ensembl":"ENSG00000198804","Gene description":"Mitochondrially encoded cytochrome c oxidase I","Uniprot":["P00395"],"Chromosome":"MT","Position":"5904-7445","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Deafness","Disease variant","Leber hereditary optic neuropathy","Non-syndromic deafness","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"222644.8","heart muscle":"255389.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"67670.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016241","HPA069328"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB016241":"AB_2229888","HPA069328":"AB_2686122"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"}},{"Gene":"MT-CO2","Gene synonym":["CO2","COX2","MTCO2"],"Ensembl":"ENSG00000198712","Gene description":"Mitochondrially encoded cytochrome c oxidase II","Uniprot":["P00403"],"Chromosome":"MT","Position":"7586-8269","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"164780.5","heart muscle":"210840.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"78921.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016243","HPA051505","HPA054758"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016243":"AB_2066366","HPA051505":"AB_2681511","HPA054758":"AB_2682595"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.89e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.10e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"}},{"Gene":"MT-CO3","Gene synonym":["CO3","COIII","COX3","MTCO3"],"Ensembl":"ENSG00000198938","Gene description":"Mitochondrially encoded cytochrome c oxidase III","Uniprot":["P00414"],"Chromosome":"MT","Position":"9207-9990","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Leber hereditary optic neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"189825.4","heart muscle":"231090.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"84798.7","Horizontal cells":"59830.8","Rod photoreceptor cells":"57689.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042788"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042788":"AB_10793985"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.01e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"}},{"Gene":"MT-CYB","Gene synonym":["COB","CYTB","MTCYB","UQCR3"],"Ensembl":"ENSG00000198727","Gene description":"Mitochondrially encoded cytochrome b","Uniprot":["P00156"],"Chromosome":"MT","Position":"14747-15887","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Cataract","Deafness","Disease variant","Leber hereditary optic neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"130283.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"61574.2","Cardiomyocytes":"60359.4","Rod photoreceptor cells":"38637.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032215","HPA068400","HPA074796"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB032215":"AB_2261378","HPA068400":"AB_2685982","HPA074796":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.96e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"MT-ND1","Gene synonym":["MTND1","NAD1","ND1"],"Ensembl":"ENSG00000198888","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1","Uniprot":["P03886"],"Chromosome":"MT","Position":"3307-4262","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Alzheimer disease","Amyloidosis","Diabetes mellitus","Disease variant","Epilepsy","FDA approved drug targets","Leber hereditary optic neuropathy","MELAS syndrome","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"111350.7","heart muscle":"127951.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"21963.9","Cardiomyocytes":"30786.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"9432.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"9432.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033779","HPA066847"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033779":"AB_2149736","HPA066847":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.63e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"}},{"Gene":"MT-ND2","Gene synonym":["MTND2","NAD2","ND2"],"Ensembl":"ENSG00000198763","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2","Uniprot":["P03891"],"Chromosome":"MT","Position":"4470-5511","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Alzheimer disease","Amyloidosis","Disease variant","Leber hereditary optic neuropathy","Leigh syndrome","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"101525.8","heart muscle":"130517.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"33265.3","Proximal enterocytes":"18614.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"16754.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"16754.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"}},{"Gene":"MT-ND3","Gene synonym":["MTND3","NAD3","ND3"],"Ensembl":"ENSG00000198840","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3","Uniprot":["P03897"],"Chromosome":"MT","Position":"10059-10404","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Leigh syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"184151.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"23877.6","Cardiomyocytes":"24734.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063296"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA063296":"AB_2684978"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.63e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"}},{"Gene":"MT-ND4","Gene synonym":["LHON","MTND4","NAD4","ND4"],"Ensembl":"ENSG00000198886","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4","Uniprot":["P03905"],"Chromosome":"MT","Position":"10760-12137","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Dystonia","Leber hereditary optic neuropathy","MELAS syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"196536.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"58448.2","Cardiomyocytes":"106696.0","Rod photoreceptor cells":"47132.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"13456.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053928"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA053928":"AB_2682313"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.76e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"}},{"Gene":"MT-ND4L","Gene synonym":["MTND4L","NAD4L","ND4L"],"Ensembl":"ENSG00000212907","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L","Uniprot":["P03901"],"Chromosome":"MT","Position":"10470-10766","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Leber hereditary optic neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"132930.7","heart muscle":"145078.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"27304.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075648"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"HPA075648":"AB_2686760"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"}},{"Gene":"MT-ND5","Gene synonym":["MTND5","NAD5","ND5"],"Ensembl":"ENSG00000198786","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5","Uniprot":["P03915"],"Chromosome":"MT","Position":"12337-14148","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Leber hereditary optic neuropathy","Leigh syndrome","MELAS syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"25147.7","heart muscle":"26116.9","skeletal muscle":"25697.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"32207.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"}},{"Gene":"MT-ND6","Gene synonym":["MTND6","NAD6","ND6"],"Ensembl":"ENSG00000198695","Gene description":"Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6","Uniprot":["P03923"],"Chromosome":"MT","Position":"14149-14673","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Dystonia","Leber hereditary optic neuropathy","Leigh syndrome","MELAS syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"35802.7","skeletal muscle":"57879.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Cardiomyocytes":"12019.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.91e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"}},{"Gene":"MTARC1","Gene synonym":["FLJ22390","MARC1","MOSC1"],"Ensembl":"ENSG00000186205","Gene description":"Mitochondrial amidoxime reducing component 1","Uniprot":["Q5VT66"],"Chromosome":"1","Position":"220786913-220819659","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"192.3","breast":"86.2","liver":"84.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"112.3","Extravillous trophoblasts":"44.1","Prostatic glandular cells":"40.7","Syncytiotrophoblasts":"74.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"14.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"basophil":"30.2","classical monocyte":"33.6","eosinophil":"12.3","neutrophil":"42.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"31","RNA blood lineage specific nTPM":{"granulocytes":"42.8","monocytes":"33.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"70.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Prostate - Prostate glandular cells","Skin - Adipocytes (Skin)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028702"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA028702":"AB_10601135"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.51e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"}},{"Gene":"MTARC2","Gene synonym":["FLJ20605","MARC2","MOSC2"],"Ensembl":"ENSG00000117791","Gene description":"Mitochondrial amidoxime reducing component 2","Uniprot":["Q969Z3"],"Chromosome":"1","Position":"220748225-220784815","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"132.5","liver":"223.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"90.6","Proximal enterocytes":"62.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"35.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"14.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"14.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015085","HPA017572"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015085":"AB_1848780","HPA017572":"AB_1848778"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.40e-10"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"}},{"Gene":"MTCL1","Gene synonym":["CCDC165","KIAA0802","SOGA2"],"Ensembl":"ENSG00000168502","Gene description":"Microtubule crosslinking factor 1","Uniprot":["Q9Y4B5"],"Chromosome":"18","Position":"8705661-8832778","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"90.1","intestine":"28.1","retina":"34.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"73.2","Cone photoreceptor cells":"41.4","Excitatory neurons":"85.3","Inhibitory neurons":"78.5","Muller glia cells":"59.1","Rod photoreceptor cells":"115.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"9","RNA brain regional specific nTPM":{"cerebellum":"90.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Outer root sheath cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"32.0"},"Antibody":["HPA046245"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046245":"AB_10962580"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.45e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"}},{"Gene":"MTDH","Gene synonym":["3D3","AEG-1","LYRIC"],"Ensembl":"ENSG00000147649","Gene description":"Metadherin","Uniprot":["Q86UE4"],"Chromosome":"8","Position":"97644184-97730260","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"817.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010932","HPA015104","CAB068204","CAB068205"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"300000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB068204":"AB_2665655","CAB068205":"AB_2665654","HPA010932":"AB_1079422","HPA015104":"AB_1854173"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.76e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.82e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"}},{"Gene":"MTFP1","Gene synonym":["HSPC242","MTP18"],"Ensembl":"ENSG00000242114","Gene description":"Mitochondrial fission process 1","Uniprot":["Q9UDX5"],"Chromosome":"22","Position":"30425623-30429054","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"65.7","Exocrine glandular cells":"49.1","Pancreatic endocrine cells":"46.4","Undifferentiated cells":"51.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077396"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA077396":"AB_2686837"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"}},{"Gene":"MTHFD1","Gene synonym":["MTHFC","MTHFD"],"Ensembl":"ENSG00000100714","Gene description":"Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1","Uniprot":[],"Chromosome":"14","Position":"64388031-64463457","Protein class":["Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"356.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"145.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000704","HPA001290","HPA015006","HPA050052"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA000704":"AB_1079424","HPA001290":"AB_1854177","HPA015006":"AB_1854178","HPA050052":"AB_2680998"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.96e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.93e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"}},{"Gene":"MTHFD1L","Gene synonym":["DKFZP586G1517","FLJ21145","FTHFSDC1"],"Ensembl":"ENSG00000120254","Gene description":"Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like","Uniprot":["Q6UB35"],"Chromosome":"6","Position":"150865679-151101887","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["One-carbon metabolism"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"82.8","Extravillous trophoblasts":"186.1","Granulosa cells":"86.0","Microglial cells":"123.1","Syncytiotrophoblasts":"86.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"1.1","T-cells":"1.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015006","HPA029040","HPA029041","HPA050052","HPA074911"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"89000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA015006":"AB_1854178","HPA029040":"AB_2672879","HPA029041":"AB_2672880","HPA050052":"AB_2680998","HPA074911":"AB_2686723"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.68e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.28e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.10e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.33e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.69e-5"}},{"Gene":"MTLN","Gene synonym":["LEMP","LINC00116","MOXI","MPM","NCRNA00116","SMIM37"],"Ensembl":"ENSG00000175701","Gene description":"Mitoregulin","Uniprot":["Q8NCU8"],"Chromosome":"2","Position":"110211529-110245420","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"229.3","skeletal muscle":"784.7","tongue":"280.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"612.5","Distal tubular cells":"279.9","Proximal tubular cells":"308.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"}},{"Gene":"MTMR10","Gene synonym":["FLJ20313"],"Ensembl":"ENSG00000166912","Gene description":"Myotubularin related protein 10","Uniprot":["Q9NXD2"],"Chromosome":"15","Position":"30938941-30991628","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"83.5","Oligodendrocytes":"140.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"13.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006081"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA006081":"AB_2667508"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.77e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"}},{"Gene":"MTNR1A","Gene synonym":["MEL-1A-R"],"Ensembl":"ENSG00000168412","Gene description":"Melatonin receptor 1A","Uniprot":["P48039"],"Chromosome":"4","Position":"186533655-186555567","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.0","intestine":"1.2","kidney":"2.1","testis":"1.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"9","RNA brain regional specific nTPM":{"cerebellum":"1.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"1.4"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MTNR1B","Gene synonym":[],"Ensembl":"ENSG00000134640","Gene description":"Melatonin receptor 1B","Uniprot":["P49286"],"Chromosome":"11","Position":"92969651-92985066","Protein class":["FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"3.1","placenta":"1.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"3.6","testis cancer":"1.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074024"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074024":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"}},{"Gene":"MTO1","Gene synonym":[],"Ensembl":"ENSG00000135297","Gene description":"Mitochondrial tRNA translation optimization 1","Uniprot":["Q9Y2Z2"],"Chromosome":"6","Position":"73461578-73509236","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"141.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030230","HPA030232"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA030230":"AB_10598910","HPA030232":"AB_10600891"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"}},{"Gene":"MTUS1","Gene synonym":["ATBP","ATIP1","ATIP3","DKFZp586D1519","FLJ14295","ICIS","KIAA1288","MP44","MTSG1"],"Ensembl":"ENSG00000129422","Gene description":"Microtubule associated scaffold protein 1","Uniprot":["Q9ULD2"],"Chromosome":"8","Position":"17643795-17800917","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"403.7","Oligodendrocytes":"442.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"1.8","naive CD8 T-cell":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"T-cells":"1.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067903","HPA069795"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoli","Microtubules"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoli","Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA067903":"AB_2685921","HPA069795":"AB_2686198"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"}},{"Gene":"MTX1","Gene synonym":["MTX","MTXN"],"Ensembl":"ENSG00000173171","Gene description":"Metaxin 1","Uniprot":["Q13505"],"Chromosome":"1","Position":"155208695-155213824","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"245.1","Late spermatids":"924.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Macrophages","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011543"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA011543":"AB_1853824"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"}},{"Gene":"MUC1","Gene synonym":["ADMCKD","ADMCKD1","CD227","MCD","MCKD","MCKD1","PEM","PUM"],"Ensembl":"ENSG00000185499","Gene description":"Mucin 1, cell surface associated","Uniprot":["P15941"],"Chromosome":"1","Position":"155185824-155192916","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"485.8","stomach 1":"1064.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"973.8","Alveolar cells type 2":"1409.1","Exocrine glandular cells":"988.8","Gastric mucus-secreting cells":"578.9","Ionocytes":"454.7","Respiratory ciliated cells":"564.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"1.2"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"T-cells":"1.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"158.7","pancreatic cancer":"182.5"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Colon - Mitotic cells (Colon)","Lung - Alveolar cells type 2","Skin - Sebaceous gland cells","Stomach - Gastric mucous cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000036","CAB001986","HPA004179","HPA007235","HPA008855","CAB080102","CAB080103"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4000000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB000036":"AB_2148557","CAB001986":null,"CAB080102":null,"CAB080103":null,"HPA004179":"AB_1846282","HPA007235":"AB_1846281","HPA008855":"AB_1846283"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.60e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"}},{"Gene":"MUC12","Gene synonym":["MUC11"],"Ensembl":"ENSG00000205277","Gene description":"Mucin 12, cell surface associated","Uniprot":["Q9UKN1"],"Chromosome":"7","Position":"100969623-101018949","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"intestine":"67.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"610.7","Intestinal goblet cells":"99.6","Paneth cells":"169.9","Undifferentiated cells":"113.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"colorectal cancer":"13.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"66","RNA cell line specific nTPM":{"colorectal cancer":"9.2"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023835"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023835":"AB_1854199"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"}},{"Gene":"MUC13","Gene synonym":["DRCC1"],"Ensembl":"ENSG00000173702","Gene description":"Mucin 13, cell surface associated","Uniprot":["Q9H3R2"],"Chromosome":"3","Position":"124905442-124953819","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"intestine":"614.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"437.7","Endometrial ciliated cells":"117.6","Enteroendocrine cells":"163.6","Intestinal goblet cells":"440.6","Paneth cells":"328.1","Proximal enterocytes":"406.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"198.4","stomach cancer":"152.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"166.1","Gastric cancer":"61.9"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045163","HPA079663"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045163":"AB_10960396","HPA079663":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.73e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"}},{"Gene":"MUC15","Gene synonym":[],"Ensembl":"ENSG00000169550","Gene description":"Mucin 15, cell surface associated","Uniprot":["Q8N387"],"Chromosome":"11","Position":"26559032-26572263","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"26","RNA tissue specific nTPM":{"epididymis":"1949.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"965.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"thyroid cancer":"56.7"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"basal ganglia":"4.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"12.0"},"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Prostate - Prostate basal glandular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"cerebellum":"1.2","thalamus":"1.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026110","HPA073304"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026110":"AB_1854200","HPA073304":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-5"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-3"}},{"Gene":"MUC16","Gene synonym":["CA125","FLJ14303"],"Ensembl":"ENSG00000181143","Gene description":"Mucin 16, cell surface associated","Uniprot":["Q8WXI7"],"Chromosome":"19","Position":"8848844-8981342","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adipose tissue":"7.2","cervix":"15.9","fallopian tube":"5.9","salivary gland":"6.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"89.7","Glandular and luminal cells":"172.4","Ionocytes":"228.5","Respiratory ciliated cells":"242.0","Salivary duct cells":"119.9","Thymic epithelial cells":"437.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"ovarian cancer":"21.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"22.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Respiratory ciliated cells","Prostate - Urothelial cells","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB055172","HPA065600"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"25000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB055172":"AB_2148831","HPA065600":"AB_2732736"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"}},{"Gene":"MUC17","Gene synonym":[],"Ensembl":"ENSG00000169876","Gene description":"Mucin 17, cell surface associated","Uniprot":["Q685J3"],"Chromosome":"7","Position":"101020072-101058859","Protein class":["Cancer-related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"62","RNA tissue specific nTPM":{"intestine":"42.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Proximal enterocytes":"314.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"22.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"5.9","Gastric cancer":"12.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031634"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031634":"AB_10603021"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"MUC21","Gene synonym":["bCX31G15.2","C6orf205"],"Ensembl":"ENSG00000204544","Gene description":"Mucin 21, cell surface associated","Uniprot":["Q5SSG8"],"Chromosome":"6","Position":"30983718-30989903","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"135.8","esophagus":"696.3","vagina":"244.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"524.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"cervical cancer":"6.8","head and neck cancer":"6.6","lung cancer":"13.9","stomach cancer":"7.0","thyroid cancer":"5.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"18","RNA cell line specific nTPM":{"lung cancer":"2.2"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052028"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052028":"AB_2681700"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-4"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"}},{"Gene":"MUC3A","Gene synonym":["MUC3"],"Ensembl":"ENSG00000169894","Gene description":"Mucin 3A, cell surface associated","Uniprot":["Q02505"],"Chromosome":"7","Position":"100949534-100968347","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"13.8","intestine":"41.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"170.6","Intestinal goblet cells":"185.0","Paneth cells":"143.0","Proximal enterocytes":"388.8","Undifferentiated cells":"124.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"16.4","pancreatic cancer":"14.0","stomach cancer":"29.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"8.1","Gastric cancer":"4.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"cerebellum":"16.5"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010871","HPA047868"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA010871":"AB_1854201","HPA047868":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"}},{"Gene":"MUC4","Gene synonym":[],"Ensembl":"ENSG00000145113","Gene description":"Mucin 4, cell surface associated","Uniprot":["Q99102"],"Chromosome":"3","Position":"195746765-195811973","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"19.2","intestine":"31.1","prostate":"14.8","vagina":"15.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"218.5","Distal enterocytes":"183.5","Gastric mucus-secreting cells":"146.1","Intestinal goblet cells":"138.7","Ionocytes":"310.4","Respiratory ciliated cells":"380.2","Salivary duct cells":"112.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"16.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"3.4","head and neck cancer":"5.2","pancreatic cancer":"2.7"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Respiratory ciliated cells","Prostate - Urothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"16","RNA pig brain regional specific nTPM":{"basal ganglia":"3.4"},"Antibody":["HPA005895","CAB013536"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013536":null,"HPA005895":"AB_1079427"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-3"}},{"Gene":"MUCL3","Gene synonym":["bCX105N19.6","C6orf37","DPCR1","PBLT"],"Ensembl":"ENSG00000168631","Gene description":"Mucin like 3","Uniprot":["Q3MIW9"],"Chromosome":"6","Position":"30934523-30954221","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"stomach 1":"202.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"984.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"pancreatic cancer":"56.8","stomach cancer":"55.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"ovarian cancer":"12.6","pancreatic cancer":"10.2"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014036"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014036":"AB_1847841"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.58e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"}},{"Gene":"MUSK","Gene synonym":[],"Ensembl":"ENSG00000030304","Gene description":"Muscle associated receptor tyrosine kinase","Uniprot":["O15146"],"Chromosome":"9","Position":"110668779-110806558","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein","Kinase","Muscle protein","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.2","skeletal muscle":"4.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"15.8","Oligodendrocytes":"16.0","Peritubular cells":"37.3","Skeletal myocytes":"15.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"Sarcoma":"4.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"5.0"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"}},{"Gene":"MVD","Gene synonym":["MPD"],"Ensembl":"ENSG00000167508","Gene description":"Mevalonate diphosphate decarboxylase","Uniprot":["P53602"],"Chromosome":"16","Position":"88651935-88663161","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"144.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041404","HPA048250"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA041404":"AB_2677457","HPA048250":"AB_2680329"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"}},{"Gene":"MXRA8","Gene synonym":["DKFZp586E2023"],"Ensembl":"ENSG00000162576","Gene description":"Matrix remodeling associated 8","Uniprot":["Q9BRK3"],"Chromosome":"1","Position":"1352689-1361777","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"150.8","Extravillous trophoblasts":"294.8","Fibroblasts":"183.8","Leydig cells":"169.3","Peritubular cells":"176.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"naive CD8 T-cell":"6.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"64","RNA blood lineage specific nTPM":{"T-cells":"6.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"56.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Breast - Fibroblasts","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Liver - Hepatic stellate cells","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053958","HPA055780"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"760000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA053958":"AB_2682322","HPA055780":"AB_2682918"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.43e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.93e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.87e-4"}},{"Gene":"MYADM","Gene synonym":[],"Ensembl":"ENSG00000179820","Gene description":"Myeloid associated differentiation marker","Uniprot":["Q96S97"],"Chromosome":"19","Position":"53864763-53876435","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"207.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Prostate - Smooth muscle cells","Skeletal muscle - Fibroblasts","Testis - Spermatocytes","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056301"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"27000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA056301":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.15e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.71e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-3"}},{"Gene":"MYADML2","Gene synonym":["LOC255275"],"Ensembl":"ENSG00000185105","Gene description":"Myeloid associated differentiation marker like 2","Uniprot":["A6NDP7"],"Chromosome":"17","Position":"81939645-81947233","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"84.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"4.1","Horizontal cells":"5.8","Inhibitory neurons":"2.3","Skeletal myocytes":"13.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"1.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"3.0"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041856","HPA048476"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041856":"AB_2677709","HPA048476":"AB_2680410"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"}},{"Gene":"MYC","Gene synonym":["bHLHe39","c-Myc","MYCC"],"Ensembl":"ENSG00000136997","Gene description":"MYC proto-oncogene, bHLH transcription factor","Uniprot":["P01106"],"Chromosome":"8","Position":"127735434-127742951","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"254.6","skin 1":"289.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"608.5","Basal squamous epithelial cells":"1003.2","Squamous epithelial cells":"684.3","Suprabasal keratinocytes":"640.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000084","CAB010307","HPA055893","HPA066556"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000084":null,"CAB010307":"AB_631274","HPA055893":"AB_2682960","HPA066556":"AB_2685691"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.52e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.49e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.96e-5"}},{"Gene":"MYCBP2","Gene synonym":["FLJ10106","KIAA0916","PAM","PHR1"],"Ensembl":"ENSG00000005810","Gene description":"MYC binding protein 2","Uniprot":["O75592"],"Chromosome":"13","Position":"77044657-77327094","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Ubl conjugation pathway"],"Molecular function":["Guanine-nucleotide releasing factor","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"419.4","Inhibitory neurons":"460.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058807"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA058807":"AB_2732627"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.01e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"}},{"Gene":"MYCT1","Gene synonym":["FLJ21269","MTLC"],"Ensembl":"ENSG00000120279","Gene description":"MYC target 1","Uniprot":["Q8N699"],"Chromosome":"6","Position":"152697895-152724567","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"49.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"118.5","Endothelial cells":"130.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"33","RNA blood cell specific nTPM":{"eosinophil":"30.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"248","RNA blood lineage specific nTPM":{"granulocytes":"30.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"5.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Sinusoid Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047992"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA047992":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"}},{"Gene":"MYD88","Gene synonym":[],"Ensembl":"ENSG00000172936","Gene description":"MYD88 innate immune signal transduction adaptor","Uniprot":["Q99836"],"Chromosome":"3","Position":"38138478-38143022","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Immunity","Inflammatory response","Innate immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"73.2","monocytes":"131.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009104"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles","Mitochondria"],"Antibody RRID":{"CAB009104":"AB_2146724"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.45e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"}},{"Gene":"MYEOV","Gene synonym":["OCIM"],"Ensembl":"ENSG00000172927","Gene description":"Myeloma overexpressed","Uniprot":["Q96EZ4"],"Chromosome":"11","Position":"69294151-69367726","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"5.4","breast":"5.3","esophagus":"9.6","stomach 1":"6.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"36.4","Breast myoepithelial cells":"32.1","Club cells":"12.2","Ductal cells":"12.9","Gastric mucus-secreting cells":"20.9","Paneth cells":"19.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Prostate - Urothelial cells","Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012949"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA012949":"AB_1854241"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.00e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.54e-7"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.48e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"}},{"Gene":"MYH14","Gene synonym":["DFNA4","FLJ13881","KIAA2034","MHC16","MYH17"],"Ensembl":"ENSG00000105357","Gene description":"Myosin heavy chain 14","Uniprot":["Q7Z406"],"Chromosome":"19","Position":"50188186-50310542","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell shape"],"Molecular function":["Actin-binding","Calmodulin-binding","Motor protein","Myosin"],"Disease involvement":["Deafness","Disease variant","Neuropathy","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"191.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"305.8","Paneth cells":"209.2","Proximal enterocytes":"363.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Colon - Colon enterocytes","Liver - Hepatocytes","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062391","HPA067889","HPA070260"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9600000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA062391":"AB_2684748","HPA067889":"AB_2685917","HPA070260":"AB_2686243"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.97e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.83e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"}},{"Gene":"MYH15","Gene synonym":["KIAA1000"],"Ensembl":"ENSG00000144821","Gene description":"Myosin heavy chain 15","Uniprot":["Q9Y2K3"],"Chromosome":"3","Position":"108380368-108529322","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding","Calmodulin-binding","Motor protein","Muscle protein","Myosin"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.9","retina":"2.8","tongue":"1.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"6.2","Astrocytes":"13.6","Cone photoreceptor cells":"10.3","Excitatory neurons":"8.7","Inhibitory neurons":"6.2","Muller glia cells":"6.5","Oligodendrocytes":"10.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"7.6"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034871","HPA057915"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA034871":"AB_10669996","HPA057915":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"}},{"Gene":"MYH7B","Gene synonym":["dJ756N5.1","KIAA1512","MHC14","MYH14"],"Ensembl":"ENSG00000078814","Gene description":"Myosin heavy chain 7B","Uniprot":["A7E2Y1"],"Chromosome":"20","Position":"34955810-35002437","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding","Motor protein","Muscle protein","Myosin"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"heart muscle":"352.2","skeletal muscle":"157.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"91.9","Early spermatids":"20.8","Late spermatids":"72.0","Skeletal myocytes":"48.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"3.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"5.4"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Skeletal muscle - Skeletal myocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.44e-5"}},{"Gene":"MYL10","Gene synonym":["MGC3479","MYLC2PL","PLRLC"],"Ensembl":"ENSG00000106436","Gene description":"Myosin light chain 10","Uniprot":["Q9BUA6"],"Chromosome":"7","Position":"101613330-101629296","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Peritubular cells":"2.8","Skeletal myocytes":"8.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"10.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019763","HPA039262"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA019763":"AB_1854243","HPA039262":"AB_2676418"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"}},{"Gene":"MYL4","Gene synonym":["ALC1","AMLC","GT1","PRO1957"],"Ensembl":"ENSG00000198336","Gene description":"Myosin light chain 4","Uniprot":["P12829"],"Chromosome":"17","Position":"47200446-47223679","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein","Muscle protein","Myosin"],"Disease involvement":["Atrial fibrillation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"47","RNA tissue specific nTPM":{"heart muscle":"6347.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"2143.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"11.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"plasmacytoid DC":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"1.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"22","RNA cell line specific nTPM":{"Leukemia":"69.9","Sarcoma":"44.2","testis cancer":"24.3"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"amygdala":"25.8","cerebral cortex":"88.4","hippocampal formation":"25.2","white matter":"50.9"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046859","HPA051884","HPA063034"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3100000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA046859":"AB_2679842","HPA051884":"AB_2681651","HPA063034":"AB_2684927"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"}},{"Gene":"MYL7","Gene synonym":["MYL2A","MYLC2A"],"Ensembl":"ENSG00000106631","Gene description":"Myosin light chain 7","Uniprot":["Q01449"],"Chromosome":"7","Position":"44138864-44141332","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein","Muscle protein","Myosin"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"1061","RNA tissue specific nTPM":{"heart muscle":"23165.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"45","RNA single cell type specific nTPM":{"Cardiomyocytes":"8539.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"testis cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"testis cancer":"47.6","Uterine cancer":"12.5"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013331","CAB033884","HPA039262"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033884":"AB_2266773","HPA013331":"AB_1854245","HPA039262":"AB_2676418"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"}},{"Gene":"MYLK","Gene synonym":["MLCK","MLCK1","MYLK1","smMLCK"],"Ensembl":"ENSG00000065534","Gene description":"Myosin light chain kinase","Uniprot":["Q15746"],"Chromosome":"3","Position":"123610049-123884332","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Actin-binding","Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Aortic aneurysm","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"seminal vesicle":"1700.3","smooth muscle":"2137.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"917.4","Peritubular cells":"716.6","Sertoli cells":"223.9","Smooth muscle cells":"552.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"7.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"98.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Colon - Smooth muscle cells","Heart muscle - Smooth muscle cells","Kidney - Fibroblasts","Prostate - Smooth muscle cells","Skeletal muscle - Smooth muscle cells","Skin - Smooth muscle cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020789","HPA031677","HPA048055"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB020789":null,"HPA031677":"AB_10794617","HPA048055":"AB_2732543"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.04e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.46e-4"}},{"Gene":"MYLK2","Gene synonym":["KMLC","MLCK2","skMLCK"],"Ensembl":"ENSG00000101306","Gene description":"Myosin light chain kinase 2","Uniprot":["Q9H1R3"],"Chromosome":"20","Position":"31819308-31834689","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"skeletal muscle":"732.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"27","RNA single cell type specific nTPM":{"Skeletal myocytes":"74.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059704","HPA059890"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA059704":"AB_2684108","HPA059890":"AB_2684153"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.00e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"}},{"Gene":"MYLK3","Gene synonym":["caMLCK","MLCK"],"Ensembl":"ENSG00000140795","Gene description":"Myosin light chain kinase 3","Uniprot":["Q32MK0"],"Chromosome":"16","Position":"46702282-46790407","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"heart muscle":"103.4","skeletal muscle":"46.5","tongue":"72.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Cardiomyocytes":"225.2","Endometrial ciliated cells":"57.3","Skeletal myocytes":"85.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"5.5","testis cancer":"3.5"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Podocytes","Lung - Respiratory ciliated cells","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"cerebral cortex":"9.6","hippocampal formation":"5.1"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"hippocampal formation":"3.5"},"Antibody":["HPA073447"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA073447":"AB_2732225"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"}},{"Gene":"MYLK4","Gene synonym":["SgK085"],"Ensembl":"ENSG00000145949","Gene description":"Myosin light chain kinase family member 4","Uniprot":["Q86YV6"],"Chromosome":"6","Position":"2663629-2750922","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"skeletal muscle":"30.1","tongue":"72.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"7.7","Inhibitory neurons":"7.1","Microglial cells":"4.6","Oligodendrocyte precursor cells":"7.7","Skeletal myocytes":"8.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015860"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoli","Vesicles"],"Antibody RRID":{"HPA015860":"AB_2147922"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"}},{"Gene":"MYLPF","Gene synonym":["HUMMLC2B","MRLC2","MYL11"],"Ensembl":"ENSG00000180209","Gene description":"Myosin light chain, phosphorylatable, fast skeletal muscle","Uniprot":["Q96A32"],"Chromosome":"16","Position":"30370934-30377991","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein","Muscle protein","Myosin"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"108","RNA tissue specific nTPM":{"skeletal muscle":"19905.3","tongue":"5921.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"412","RNA single cell type specific nTPM":{"Skeletal myocytes":"9661.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"15.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"73","RNA blood cell specific nTPM":{"plasmacytoid DC":"19.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"73","RNA blood lineage specific nTPM":{"dendritic cells":"19.6"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Sarcoma":"59.5"},"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039262","HPA055059"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039262":"AB_2676418","HPA055059":"AB_2732591"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"}},{"Gene":"MYMK","Gene synonym":["TMEM226","TMEM8C"],"Ensembl":"ENSG00000187616","Gene description":"Myomaker, myoblast fusion factor","Uniprot":["A6NI61"],"Chromosome":"9","Position":"133514586-133528612","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Myogenesis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"85","RNA cell line specific nTPM":{"Sarcoma":"8.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051846","HPA055785"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051846":"AB_2681636","HPA055785":"AB_2682920"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"MYO15B","Gene synonym":["MYO15BP"],"Ensembl":"ENSG00000266714","Gene description":"Myosin XVB","Uniprot":["Q96JP2"],"Chromosome":"17","Position":"75588058-75626849","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"179.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"170.3","Intestinal goblet cells":"82.1","Paneth cells":"158.4","Proximal enterocytes":"253.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"18.2","Leukemia":"17.5"},"RNA tissue cell type enrichment":["Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022857","HPA023105"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA022857":"AB_1848813","HPA023105":"AB_1859526"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.34e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.90e-5"}},{"Gene":"MYO1E","Gene synonym":["HuncM-IC","MGC104638","MYO1C"],"Ensembl":"ENSG00000157483","Gene description":"Myosin IE","Uniprot":["Q12965"],"Chromosome":"15","Position":"59132434-59372871","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding","Calmodulin-binding","Motor protein","Myosin"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"301.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"23.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003003","HPA023886"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA003003":null,"HPA023886":"AB_1854253"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.19e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.57e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.99e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"}},{"Gene":"MYO7A","Gene synonym":["DFNA11","DFNB2","NSRD2","USH1B"],"Ensembl":"ENSG00000137474","Gene description":"Myosin VIIA","Uniprot":["Q13402"],"Chromosome":"11","Position":"77128246-77215241","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":["Actin-binding","Calmodulin-binding","Motor protein","Myosin"],"Disease involvement":["Deafness","Disease variant","Leber congenital amaurosis","Non-syndromic deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"41.9","choroid plexus":"53.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"17.6","Cone photoreceptor cells":"22.4","Cytotrophoblasts":"43.7","Hofbauer cells":"25.9","Muller glia cells":"15.6","Rod photoreceptor cells":"33.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"2.6","intermediate monocyte":"1.7"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"monocytes":"2.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Kidney - Proximal tubular cells","Skeletal muscle - Macrophages","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034059"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034059":"AB_2148626"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"}},{"Gene":"MYOF","Gene synonym":["FER1L3","KIAA1207"],"Ensembl":"ENSG00000138119","Gene description":"Myoferlin","Uniprot":["Q9NZM1"],"Chromosome":"10","Position":"93306429-93482334","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"149.0","Glandular and luminal cells":"131.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"20.4","non-classical monocyte":"26.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"57","RNA blood lineage specific nTPM":{"dendritic cells":"8.1","monocytes":"26.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014245"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA014245":"AB_1848495"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.40e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"}},{"Gene":"MYORG","Gene synonym":["KIAA1161","NET37"],"Ensembl":"ENSG00000164976","Gene description":"Myogenesis regulating glycosidase (putative)","Uniprot":["Q6NSJ0"],"Chromosome":"9","Position":"34366666-34376898","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"84.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"39.9","Cholangiocytes":"26.9","Cytotrophoblasts":"55.8","Distal enterocytes":"41.6","Hepatocytes":"46.4","Paneth cells":"29.1","Proximal enterocytes":"51.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060533","HPA067487"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA060533":"AB_2684311","HPA067487":"AB_2685848"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.96e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.20e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"}},{"Gene":"MYRF","Gene synonym":["C11orf9","MRF","Ndt80","pqn-47"],"Ensembl":"ENSG00000124920","Gene description":"Myelin regulatory factor","Uniprot":["Q9Y2G1"],"Chromosome":"11","Position":"61752636-61788518","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Hydrolase","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"168.0","stomach 1":"88.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"79.6","Cholangiocytes":"52.0","Gastric mucus-secreting cells":"119.8","Oligodendrocytes":"241.5","Thymic epithelial cells":"69.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"47.4"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018310"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA018310":"AB_1845534"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"}},{"Gene":"MYRFL","Gene synonym":["bcm1377","C12orf15","C12orf28","FLJ25056"],"Ensembl":"ENSG00000166268","Gene description":"Myelin regulatory factor like","Uniprot":["Q96LU7"],"Chromosome":"12","Position":"69825227-69959097","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"23.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Inhibitory neurons":"100.2","Late spermatids":"30.9","Oligodendrocyte precursor cells":"67.4","Proximal enterocytes":"33.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"3.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049340"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA049340":"AB_2680719"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"}},{"Gene":"N4BP2L2","Gene synonym":["CG005","PFAAP5"],"Ensembl":"ENSG00000244754","Gene description":"NEDD4 binding protein 2 like 2","Uniprot":["Q92802"],"Chromosome":"13","Position":"32432417-32538885","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039338","HPA039434","HPA059327"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA039338":"AB_2676453","HPA039434":"AB_10673143","HPA059327":"AB_2683981"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-3"}},{"Gene":"NAA25","Gene synonym":["C12orf30","FLJ13089"],"Ensembl":"ENSG00000111300","Gene description":"N-alpha-acetyltransferase 25, NatB auxiliary subunit","Uniprot":["Q14CX7"],"Chromosome":"12","Position":"112026689-112108796","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"103.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039322"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039322":"AB_10697548"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.53e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"}},{"Gene":"NAALAD2","Gene synonym":["GCPIII","NAALADASE2"],"Ensembl":"ENSG00000077616","Gene description":"N-acetylated alpha-linked acidic dipeptidase 2","Uniprot":["Q9Y3Q0"],"Chromosome":"11","Position":"90131515-90192894","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Dipeptidase","Hydrolase","Metalloprotease","Multifunctional enzyme","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"19.9","testis":"13.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"107.7","Inhibitory neurons":"107.6","Oligodendrocyte precursor cells":"147.3","Oligodendrocytes":"79.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"5.1"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060820","HPA065419"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA060820":"AB_2684373","HPA065419":"AB_2685487"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"}},{"Gene":"NAALADL1","Gene synonym":[],"Ensembl":"ENSG00000168060","Gene description":"N-acetylated alpha-linked acidic dipeptidase like 1","Uniprot":["Q9UQQ1"],"Chromosome":"11","Position":"65044818-65058553","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Aminopeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"99.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Proximal enterocytes":"623.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"182.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047123"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA047123":"AB_2679942"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"}},{"Gene":"NAALADL2","Gene synonym":[],"Ensembl":"ENSG00000177694","Gene description":"N-acetylated alpha-linked acidic dipeptidase like 2","Uniprot":["Q58DX5"],"Chromosome":"3","Position":"174438573-175810548","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"301.8","Inhibitory neurons":"131.6","Microglial cells":"151.4","Oligodendrocyte precursor cells":"448.1","Oligodendrocytes":"503.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"5.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"4.0"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012413","HPA017425","CAB025586"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB025586":null,"HPA012413":"AB_1854274","HPA017425":"AB_1854275"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"}},{"Gene":"NADK","Gene synonym":["FLJ13052"],"Ensembl":"ENSG00000008130","Gene description":"NAD kinase","Uniprot":["O95544"],"Chromosome":"1","Position":"1751232-1780457","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"506.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"506.2","monocytes":"162.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048909","HPA053368"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA048909":"AB_2680553","HPA053368":"AB_2682130"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"}},{"Gene":"NAE1","Gene synonym":["APP-BP1","APPBP1","ula-1"],"Ensembl":"ENSG00000159593","Gene description":"NEDD8 activating enzyme E1 subunit 1","Uniprot":["Q13564"],"Chromosome":"16","Position":"66802875-66873256","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatogonia":"216.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041178","HPA042041"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Microtubules","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Microtubules","Centrosome"],"Antibody RRID":{"HPA041178":"AB_10964773","HPA042041":"AB_10964772"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.92e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.44e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"}},{"Gene":"NAGPA","Gene synonym":["APAA","UCE"],"Ensembl":"ENSG00000103174","Gene description":"N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase","Uniprot":["Q9UK23"],"Chromosome":"16","Position":"5024844-5034141","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"29.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"43.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064055"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7800000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064055":"AB_2685183"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.67e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"NAIP","Gene synonym":["BIRC1","NLRB1"],"Ensembl":"ENSG00000249437","Gene description":"NLR family apoptosis inhibitory protein","Uniprot":["Q13075"],"Chromosome":"5","Position":"70968166-71025339","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Protease inhibitor","Thiol protease inhibitor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"31.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"109.2","Microglial cells":"110.4","Oligodendrocytes":"167.6","Rod photoreceptor cells":"146.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"8.4","myeloid DC":"5.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"dendritic cells":"5.3","granulocytes":"4.4","monocytes":"8.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Lung - Neutrophil_2"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042438"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042438":"AB_10796578"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"}},{"Gene":"NALCN","Gene synonym":["bA430M15.1","CanIon","VGCNL1"],"Ensembl":"ENSG00000102452","Gene description":"Sodium leak channel, non-selective","Uniprot":["Q8IZF0"],"Chromosome":"13","Position":"101053776-101416508","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"13.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Astrocytes":"121.5","Excitatory neurons":"261.9","Inhibitory neurons":"270.8","Oligodendrocyte precursor cells":"311.0","Oligodendrocytes":"450.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"2.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"2.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Colon enteroendocrine cells","Liver - Hepatic stellate cells","Skin - Eccrine sweat gland cells","Testis - Peritubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031889","HPA031890","HPA031958"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031889":"AB_10669638","HPA031890":"AB_10696056","HPA031958":"AB_10601039"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"}},{"Gene":"NAP1L1","Gene synonym":["MGC23410","MGC8688","NAP1","NAP1L","NRP"],"Ensembl":"ENSG00000187109","Gene description":"Nucleosome assembly protein 1 like 1","Uniprot":["P55209"],"Chromosome":"12","Position":"76036585-76084735","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Neurogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"1823.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028861"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA028861":"AB_10603880"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.29e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.14e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"}},{"Gene":"NARF","Gene synonym":["DKFZp434G0420","FLJ10067","IOP2"],"Ensembl":"ENSG00000141562","Gene description":"Nuclear prelamin A recognition factor","Uniprot":["Q9UHQ1"],"Chromosome":"17","Position":"82458180-82490537","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"478.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053006"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA053006":"AB_2682013"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.15e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.48e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"}},{"Gene":"NAT14","Gene synonym":["KLP1"],"Ensembl":"ENSG00000090971","Gene description":"N-acetyltransferase 14 (putative)","Uniprot":["Q8WUY8"],"Chromosome":"19","Position":"55485188-55487568","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Acyltransferase","DNA-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"63.5","Cone photoreceptor cells":"50.0","Horizontal cells":"89.7","Muller glia cells":"43.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047187"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA047187":"AB_2679974"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.61e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"}},{"Gene":"NAT8","Gene synonym":["ATase2","GLA","Hcml1","TSC501"],"Ensembl":"ENSG00000144035","Gene description":"N-acetyltransferase 8 (putative)","Uniprot":["Q9UHE5"],"Chromosome":"2","Position":"73640723-73642422","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"kidney":"732.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"19","RNA single cell type specific nTPM":{"Proximal tubular cells":"1884.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"renal cancer":"242.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"liver cancer":"5.5"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067855","HPA074519"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA067855":"AB_2732774","HPA074519":"AB_2686699"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-5"}},{"Gene":"NAT8L","Gene synonym":["FLJ37478","Hcml3","Shati"],"Ensembl":"ENSG00000185818","Gene description":"N-acetyltransferase 8 like","Uniprot":["Q8N9F0"],"Chromosome":"4","Position":"2059327-2069089","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"adipose tissue":"43.5","brain":"99.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"122.7","Excitatory neurons":"45.4","Horizontal cells":"87.8","Inhibitory neurons":"36.8","Muller glia cells":"25.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"endometrial cancer":"6.2","glioma":"17.2","melanoma":"14.6","ovarian cancer":"8.0","thyroid cancer":"7.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Colon - Colon enteroendocrine cells","Kidney - Ascending Loop of Henle cells","Skin - Adipocytes (Skin)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040677"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA040677":"AB_2732486"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.01e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"}},{"Gene":"NBEA","Gene synonym":["BCL8B","FLJ10197","KIAA1544","LYST2"],"Ensembl":"ENSG00000172915","Gene description":"Neurobeachin","Uniprot":["Q8NFP9"],"Chromosome":"13","Position":"34942270-35673022","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"23.5","retina":"65.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"1001.0","Inhibitory neurons":"930.7","Oligodendrocyte precursor cells":"447.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"38.6"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039730","HPA040385"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Nucleoli","Cytosol"],"Antibody RRID":{"HPA039730":"AB_10794202","HPA040385":"AB_10795523"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.86e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"}},{"Gene":"NBEAL1","Gene synonym":["ALS2CR16","ALS2CR17","MGC164581"],"Ensembl":"ENSG00000144426","Gene description":"Neurobeachin like 1","Uniprot":["Q6ZS30"],"Chromosome":"2","Position":"203014879-203226378","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049189","HPA049447"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA049189":"AB_2680669","HPA049447":"AB_2680771"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"}},{"Gene":"NBL1","Gene synonym":["D1S1733E","DAN","DAND1","NB","NO3"],"Ensembl":"ENSG00000158747","Gene description":"NBL1, DAN family BMP antagonist","Uniprot":["P41271"],"Chromosome":"1","Position":"19596979-19658456","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"676.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"303.6","Leydig cells":"413.2","Paneth cells":"236.9","Peritubular cells":"381.9","Proximal enterocytes":"413.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Heart muscle - Fibroblasts","Liver - Vascular Endothelial cells","Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007394","CAB026132"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8100000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026132":null,"HPA007394":"AB_10601272"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"}},{"Gene":"NCAM1","Gene synonym":["CD56","NCAM"],"Ensembl":"ENSG00000149294","Gene description":"Neural cell adhesion molecule 1","Uniprot":["P13591"],"Chromosome":"11","Position":"112961247-113278436","Protein class":["Cancer-related genes","CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"290.1","heart muscle":"145.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"514.3","Excitatory neurons":"454.5","Inhibitory neurons":"430.4","Oligodendrocyte precursor cells":"899.2","Oligodendrocytes":"956.8","Schwann cells":"253.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"31.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"NK-cell":"53.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"NK-cells":"53.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"117.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Kidney - Fibroblasts","Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000142","CAB018071","HPA039835"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1200000,"Blood concentration - Conc. blood MS [pg\/L]":"2300000000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB000142":null,"CAB018071":"AB_627129","HPA039835":"AB_2676705"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.11e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-5"}},{"Gene":"NCAM2","Gene synonym":["MGC51008","NCAM21"],"Ensembl":"ENSG00000154654","Gene description":"Neural cell adhesion molecule 2","Uniprot":["O15394"],"Chromosome":"21","Position":"20998409-21543329","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"12.0","brain":"26.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Astrocytes":"690.8","Excitatory neurons":"853.9","Inhibitory neurons":"884.7","Oligodendrocyte precursor cells":"1655.8","Oligodendrocytes":"1441.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"breast cancer":"2.6","glioma":"5.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"34.5","Rhabdoid":"16.0"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Testis - Sertoli cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030900","HPA030901"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Plasma membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nuclear bodies","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA030900":"AB_10602037","HPA030901":"AB_2673650"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"}},{"Gene":"NCDN","Gene synonym":["NCDN-1","NCDN-2"],"Ensembl":"ENSG00000020129","Gene description":"Neurochondrin","Uniprot":["Q9UBB6"],"Chromosome":"1","Position":"35557473-35567274","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"424.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"39.2","Inhibitory neurons":"34.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023676"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023676":"AB_1854325"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.91e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"}},{"Gene":"NCEH1","Gene synonym":["AADACL1","KIAA1363","NCEH"],"Ensembl":"ENSG00000144959","Gene description":"Neutral cholesterol ester hydrolase 1","Uniprot":["Q6PIU2"],"Chromosome":"3","Position":"172630249-172711218","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"82.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Ductal cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026888","HPA043873"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA026888":"AB_10601557","HPA043873":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.25e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"}},{"Gene":"NCF1","Gene synonym":["NCF1A","NOXO2","p47phox","SH3PXD1A"],"Ensembl":"ENSG00000158517","Gene description":"Neutrophil cytosolic factor 1","Uniprot":["P14598"],"Chromosome":"7","Position":"74773962-74789376","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Chronic granulomatous disease","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"86.4","lymphoid tissue":"97.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"61.1","dendritic cells":"17.8","Macrophages":"28.0","Plasma cells":"85.1","T-cells":"13.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"1165.0","classical monocyte":"673.5","eosinophil":"1467.3","neutrophil":"2128.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"2128.0","monocytes":"673.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"30.5","lymphoma":"81.5"},"RNA tissue cell type enrichment":["Kidney - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004524","HPA047836","HPA052095"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004524":"AB_627987","HPA047836":"AB_2680173","HPA052095":"AB_2681721"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"}},{"Gene":"NCKAP1","Gene synonym":["HEM2","Nap1","NAP125"],"Ensembl":"ENSG00000061676","Gene description":"NCK associated protein 1","Uniprot":["Q9Y2A7"],"Chromosome":"2","Position":"182909115-183038858","Protein class":["Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020449"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"60000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA020449":"AB_1854327"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.71e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.81e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"}},{"Gene":"NCKAP1L","Gene synonym":["HEM1"],"Ensembl":"ENSG00000123338","Gene description":"NCK associated protein 1 like","Uniprot":["P55160"],"Chromosome":"12","Position":"54497752-54548243","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"44.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"72.0","dendritic cells":"124.8","Hofbauer cells":"120.0","Kupffer cells":"115.9","Macrophages":"130.8","monocytes":"172.3","NK-cells":"93.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"60.2","Leukemia":"62.2","lymphoma":"52.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Heart muscle - Macrophages","Liver - Kupffer cells","Pancreas - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039490","HPA040772"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"33000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA039490":"AB_2676540","HPA040772":"AB_2677129"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"}},{"Gene":"NCKIPSD","Gene synonym":["AF3P21","DIP1","ORF1","SPIN90","WASLBP","WISH"],"Ensembl":"ENSG00000213672","Gene description":"NCK interacting protein with SH3 domain","Uniprot":["Q9NZQ3"],"Chromosome":"3","Position":"48673844-48686364","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"121.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Peritubular cells":"48.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019267","HPA050005"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB019267":null,"HPA050005":"AB_2680988"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.57e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.20e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"}},{"Gene":"NCLN","Gene synonym":["NET59","NICALIN"],"Ensembl":"ENSG00000125912","Gene description":"Nicalin","Uniprot":["Q969V3"],"Chromosome":"19","Position":"3185563-3209575","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006625"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Lipid droplets"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA006625":"AB_1079453"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.19e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.37e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.82e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"}},{"Gene":"NCMAP","Gene synonym":["C1orf130","FLJ42528","MP11"],"Ensembl":"ENSG00000184454","Gene description":"Non-compact myelin associated protein","Uniprot":["Q5T1S8"],"Chromosome":"1","Position":"24556087-24609328","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"7.3","pancreas":"8.5","salivary gland":"7.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"16.1","Ductal cells":"19.1","Exocrine glandular cells":"33.2","Schwann cells":"23.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"2.7"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Alveolar cells type 2","Pancreas - Ductal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"spinal cord":"147.1"},"Antibody":["HPA013656"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013656":"AB_2275006"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.83e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-3"}},{"Gene":"NCR1","Gene synonym":["CD335","LY94","NK-p46","NKP46"],"Ensembl":"ENSG00000189430","Gene description":"Natural cytotoxicity triggering receptor 1","Uniprot":["O76036"],"Chromosome":"19","Position":"54906148-54916140","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"3.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"NK-cells":"85.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.2"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"cerebral cortex":"1.0"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"NK-cell":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"NK-cells":"1.1"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - NK-cells (Liver)","Lung - NK-cells (Lung)","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"}},{"Gene":"NCR2","Gene synonym":["CD336","LY95","NK-p44"],"Ensembl":"ENSG00000096264","Gene description":"Natural cytotoxicity triggering receptor 2","Uniprot":["O95944"],"Chromosome":"6","Position":"41335608-41350889","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"17","RNA blood cell specific nTPM":{"NK-cell":"1.7","plasmacytoid DC":"4.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"dendritic cells":"4.8","NK-cells":"1.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"Leukemia":"1.2","lymphoma":"1.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067249"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA067249":"AB_2685811"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NCR3","Gene synonym":["1C7","CD337","LY117","NKp30"],"Ensembl":"ENSG00000204475","Gene description":"Natural cytotoxicity triggering receptor 3","Uniprot":["O14931"],"Chromosome":"6","Position":"31588895-31593006","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"4.0","intestine":"5.6","lymphoid tissue":"16.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"B-cells":"46.1","NK-cells":"143.8","T-cells":"50.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"274.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"21","RNA cell line specific nTPM":{"Leukemia":"2.2","lymphoma":"2.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Colon - T-cells","Heart muscle - T-cells","Lung - NK-cells (Lung)","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"}},{"Gene":"NCR3LG1","Gene synonym":["B7-H6","DKFZp686O24166"],"Ensembl":"ENSG00000188211","Gene description":"Natural killer cell cytotoxicity receptor 3 ligand 1","Uniprot":["Q68D85"],"Chromosome":"11","Position":"17351800-17377341","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"7.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"31.8","Inhibitory neurons":"28.7","Langerhans cells":"18.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"cerebellum":"4.7","cerebral cortex":"4.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024137"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024137":"AB_1859534"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.21e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"NCSTN","Gene synonym":["APH2","KIAA0253"],"Ensembl":"ENSG00000162736","Gene description":"Nicastrin","Uniprot":["Q92542"],"Chromosome":"1","Position":"160343316-160358952","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Notch signaling pathway"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"158.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB021982","HPA054846","HPA070642"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB021982":null,"HPA054846":"AB_2682624","HPA070642":"AB_2686289"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.75e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"}},{"Gene":"NDC1","Gene synonym":["FLJ10407","NET3","TMEM48"],"Ensembl":"ENSG00000058804","Gene description":"NDC1 transmembrane nucleoporin","Uniprot":["Q9BTX1"],"Chromosome":"1","Position":"53765478-53838463","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Mitotic cells (Stomach)","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069751","HPA070882"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Plasma membrane","Actin filaments"],"Antibody RRID":{"HPA069751":"AB_2686189","HPA070882":"AB_2686320"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.48e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.52e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.58e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"}},{"Gene":"NDFIP1","Gene synonym":["MGC10924","N4WBP5"],"Ensembl":"ENSG00000131507","Gene description":"Nedd4 family interacting protein 1","Uniprot":["Q9BT67"],"Chromosome":"5","Position":"142108779-142154440","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009682"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA009682":"AB_1079455"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.33e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.39e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"}},{"Gene":"NDFIP2","Gene synonym":["KIAA1165","N4wbp5a"],"Ensembl":"ENSG00000102471","Gene description":"Nedd4 family interacting protein 2","Uniprot":["Q9NV92"],"Chromosome":"13","Position":"79481124-79556075","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"255.4","Late spermatids":"322.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"12.1","eosinophil":"22.7","naive CD4 T-cell":"5.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"granulocytes":"22.7","T-cells":"5.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009160"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA009160":"AB_1079456"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.99e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.18e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"NDRG1","Gene synonym":["CAP43","DRG1","NDR1","RTP","TDD5"],"Ensembl":"ENSG00000104419","Gene description":"N-myc downstream regulated 1","Uniprot":["Q92597"],"Chromosome":"8","Position":"133237175-133302022","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"613.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"534.1","Proximal enterocytes":"394.4","Suprabasal keratinocytes":"763.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006881"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Microtubules"],"Antibody RRID":{"HPA006881":"AB_1078392"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"}},{"Gene":"NDRG2","Gene synonym":["KIAA1248","SYLD"],"Ensembl":"ENSG00000165795","Gene description":"NDRG family member 2","Uniprot":["Q9UN36"],"Chromosome":"14","Position":"21016763-21070872","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis","Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1885.3","salivary gland":"2081.6","skeletal muscle":"1828.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Melanocytes":"438.9","Muller glia cells":"492.5","Schwann cells":"416.7","Serous glandular cells":"858.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"78.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"myeloid DC":"204.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"204.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Fibroblasts","Liver - Hepatocytes","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002896","HPA003590","CAB017491"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"460000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB017491":"AB_2298331","HPA002896":"AB_1079459","HPA003590":"AB_1079458"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.71e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.43e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"}},{"Gene":"NDRG4","Gene synonym":["KIAA1180","SMAP-8"],"Ensembl":"ENSG00000103034","Gene description":"NDRG family member 4","Uniprot":["Q9ULP0"],"Chromosome":"16","Position":"58462846-58513628","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"380.7","heart muscle":"352.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"313.6","Excitatory neurons":"94.4","Horizontal cells":"298.7","Inhibitory neurons":"92.2","Muller glia cells":"72.5","Sertoli cells":"88.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"23.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"62.9","Rhabdoid":"36.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Colon - Colon enteroendocrine cells","Heart muscle - Cardiomyocytes","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015313","HPA017587"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015313":"AB_1854343","HPA017587":"AB_1854344"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"}},{"Gene":"NDST1","Gene synonym":["HSST","NST1"],"Ensembl":"ENSG00000070614","Gene description":"N-deacetylase and N-sulfotransferase 1","Uniprot":["P52848"],"Chromosome":"5","Position":"150485818-150558211","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Inflammatory response"],"Molecular function":["Hydrolase","Multifunctional enzyme","Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"58.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"1.4","classical monocyte":"5.5","eosinophil":"3.6","intermediate monocyte":"1.7","myeloid DC":"4.2","neutrophil":"5.4","non-classical monocyte":"4.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"4.2","granulocytes":"5.4","monocytes":"5.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060532"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060532":"AB_2684310"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.13e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"}},{"Gene":"NDST2","Gene synonym":["HSST2","NST2"],"Ensembl":"ENSG00000166507","Gene description":"N-deacetylase and N-sulfotransferase 2","Uniprot":["P52849"],"Chromosome":"10","Position":"73801911-73811798","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Multifunctional enzyme","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"13.3","granulocytes":"19.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051515"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA051515":"AB_2681517"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"}},{"Gene":"NDST3","Gene synonym":["HSST3"],"Ensembl":"ENSG00000164100","Gene description":"N-deacetylase and N-sulfotransferase 3","Uniprot":["O95803"],"Chromosome":"4","Position":"118033618-118258634","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Multifunctional enzyme","Transferase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"4.8","liver":"1.3","lymphoid tissue":"2.9","retina":"2.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Excitatory neurons":"296.0","Inhibitory neurons":"126.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.3"},"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056189"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056189":"AB_2683061"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"}},{"Gene":"NDST4","Gene synonym":[],"Ensembl":"ENSG00000138653","Gene description":"N-deacetylase and N-sulfotransferase 4","Uniprot":["Q9H3R1"],"Chromosome":"4","Position":"114827763-115113876","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Multifunctional enzyme","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"9.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"6.2","Inhibitory neurons":"28.6","Microglial cells":"4.6","Oligodendrocyte precursor cells":"14.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"hypothalamus":"2.3","medulla oblongata":"8.3","midbrain":"3.5","pons":"9.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"6.5","liver cancer":"2.4","lymphoma":"3.3","Sarcoma":"2.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011129"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011129":"AB_1079460"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"}},{"Gene":"NDUFA1","Gene synonym":["CI-MWFE","MWFE"],"Ensembl":"ENSG00000125356","Gene description":"NADH:ubiquinone oxidoreductase subunit A1","Uniprot":["O15239"],"Chromosome":"X","Position":"119871832-119876662","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"3350.7","Distal tubular cells":"2515.8","Proximal tubular cells":"1899.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029768","HPA054359"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA029768":"AB_2673192","HPA054359":"AB_2682461"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.48e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"}},{"Gene":"NDUFA10","Gene synonym":["CI-42k"],"Ensembl":"ENSG00000130414","Gene description":"NADH:ubiquinone oxidoreductase subunit A10","Uniprot":["O95299"],"Chromosome":"2","Position":"239892450-240025743","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"332.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"423.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059529","HPA067045","CAB070846"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB070846":"AB_11152346","HPA059529":"AB_2684051","HPA067045":"AB_2732756"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.95e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.09e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"}},{"Gene":"NDUFA11","Gene synonym":["B14.7"],"Ensembl":"ENSG00000174886","Gene description":"NADH:ubiquinone oxidoreductase subunit A11","Uniprot":["Q86Y39"],"Chromosome":"19","Position":"5891276-5904006","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"1222.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072209"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA072209":"AB_2686495"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.54e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.38e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-3"}},{"Gene":"NDUFA13","Gene synonym":["B16.6","CDA016","CGI-39","GRIM-19","GRIM19"],"Ensembl":"ENSG00000186010","Gene description":"NADH:ubiquinone oxidoreductase subunit A13","Uniprot":["Q9P0J0"],"Chromosome":"19","Position":"19515736-19529054","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Electron transport","Host-virus interaction","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"1060.0","Late spermatids":"2420.2","Proximal enterocytes":"1128.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041213"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA041213":"AB_10794988"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"}},{"Gene":"NDUFA4","Gene synonym":["CI-9k","COXFA4","MLRQ"],"Ensembl":"ENSG00000189043","Gene description":"NDUFA4 mitochondrial complex associated","Uniprot":["O00483"],"Chromosome":"7","Position":"10931943-10940153","Protein class":["Disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":["Leigh syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"513.5","skeletal muscle":"525.0","tongue":"652.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"4796.4","Distal tubular cells":"3927.6","Proximal tubular cells":"3344.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055323","HPA078265"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA055323":null,"HPA078265":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.61e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"}},{"Gene":"NDUFA4L2","Gene synonym":["COXFA4L2","FLJ26118","NUOMS"],"Ensembl":"ENSG00000185633","Gene description":"NDUFA4 mitochondrial complex associated like 2","Uniprot":["Q9NRX3"],"Chromosome":"12","Position":"57234903-57240715","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"304.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"158.9","Muller glia cells":"646.1","Sertoli cells":"420.2","Smooth muscle cells":"464.6","Suprabasal keratinocytes":"697.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"renal cancer":"356.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Kidney cancer":"205.0"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Heart muscle - Fibroblasts","Prostate - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055323","HPA078265"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA055323":null,"HPA078265":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.37e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"}},{"Gene":"NDUFA5","Gene synonym":["B13","CI-13kB","CI-13KD-B","NUFM","UQOR13"],"Ensembl":"ENSG00000128609","Gene description":"NADH:ubiquinone oxidoreductase subunit A5","Uniprot":["Q16718"],"Chromosome":"7","Position":"123536997-123557904","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"403.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1077.2","Distal tubular cells":"1035.5","Proximal tubular cells":"652.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043175"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"81000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043175":"AB_10793992"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.47e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.99e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"}},{"Gene":"NDUFA9","Gene synonym":["CI-39k","COQ11","NDUFS2L","SDR22E1"],"Ensembl":"ENSG00000139180","Gene description":"NADH:ubiquinone oxidoreductase subunit A9","Uniprot":["Q16795"],"Chromosome":"12","Position":"4649095-4694317","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"630.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042268","HPA073212"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA042268":"AB_2677922","HPA073212":"AB_2686581"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.57e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.75e-4"}},{"Gene":"NDUFB11","Gene synonym":["ESSS","Np15","NP17.3"],"Ensembl":"ENSG00000147123","Gene description":"NADH:ubiquinone oxidoreductase subunit B11","Uniprot":["Q9NX14"],"Chromosome":"X","Position":"47142216-47145038","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"717.0"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030367"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA030367":"AB_10603882"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-3"}},{"Gene":"NDUFB2","Gene synonym":["AGGG","CI-AGGG"],"Ensembl":"ENSG00000090266","Gene description":"NADH:ubiquinone oxidoreductase subunit B2","Uniprot":["O95178"],"Chromosome":"7","Position":"140690777-140722790","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"4655.7","Distal tubular cells":"1937.4","Proximal tubular cells":"2562.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051377"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA051377":"AB_2681460"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.60e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"}},{"Gene":"NDUFB3","Gene synonym":["B12"],"Ensembl":"ENSG00000119013","Gene description":"NADH:ubiquinone oxidoreductase subunit B3","Uniprot":["O43676"],"Chromosome":"2","Position":"201071433-201085750","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"704.3","tongue":"727.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1846.5","Distal tubular cells":"932.9","Proximal tubular cells":"765.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034596"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034596":"AB_10602712"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.24e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"}},{"Gene":"NDUFB4","Gene synonym":["B15"],"Ensembl":"ENSG00000065518","Gene description":"NADH:ubiquinone oxidoreductase subunit B4","Uniprot":["O95168"],"Chromosome":"3","Position":"120596328-120602507","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"945.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1569.3","Proximal tubular cells":"1198.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051739","HPA064441"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Nuclear membrane"],"Antibody RRID":{"HPA051739":"AB_2681585","HPA064441":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.79e-4"}},{"Gene":"NDUFB5","Gene synonym":["CI-SGDH","MGC12314","SGDH"],"Ensembl":"ENSG00000136521","Gene description":"NADH:ubiquinone oxidoreductase subunit B5","Uniprot":["O43674"],"Chromosome":"3","Position":"179604690-179627647","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"241.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"507.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005640"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA005640":"AB_1079461"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.32e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"}},{"Gene":"NDUFB6","Gene synonym":["B17","CI"],"Ensembl":"ENSG00000165264","Gene description":"NADH:ubiquinone oxidoreductase subunit B6","Uniprot":["O95139"],"Chromosome":"9","Position":"32553001-32573184","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"866.7","Early spermatids":"1020.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044001","HPA053334"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA044001":"AB_10959448","HPA053334":"AB_2682116"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.18e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.47e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"}},{"Gene":"NDUFB8","Gene synonym":["ASHI","CI-ASHI"],"Ensembl":"ENSG00000166136","Gene description":"NADH:ubiquinone oxidoreductase subunit B8","Uniprot":["O95169"],"Chromosome":"10","Position":"100523740-100530000","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"908.0","Proximal tubular cells":"902.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003886","HPA065549"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA003886":"AB_1079463","HPA065549":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"}},{"Gene":"NDUFC1","Gene synonym":["KFYI"],"Ensembl":"ENSG00000109390","Gene description":"NADH:ubiquinone oxidoreductase subunit C1","Uniprot":["O43677"],"Chromosome":"4","Position":"139266880-139302551","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"heart muscle":"83.5","skeletal muscle":"268.3","tongue":"158.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"2877.8","Distal tubular cells":"1240.8","Proximal tubular cells":"1516.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044556","HPA062427"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA044556":"AB_10794402","HPA062427":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.23e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.25e-4"}},{"Gene":"NDUFC2","Gene synonym":["B14.5b","HLC-1"],"Ensembl":"ENSG00000151366","Gene description":"NADH:ubiquinone oxidoreductase subunit C2","Uniprot":["O95298"],"Chromosome":"11","Position":"78068297-78079862","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"889.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Skin - Sebaceous gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038873","HPA056195"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA038873":"AB_10673480","HPA056195":"AB_2683063"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.00e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-3"}},{"Gene":"NDUFC2-KCTD14","Gene synonym":[],"Ensembl":"ENSG00000259112","Gene description":"NDUFC2-KCTD14 readthrough","Uniprot":["E9PQ53"],"Chromosome":"11","Position":"78016971-78079865","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"5.8","Erythroid cells":"3.0","Excitatory neurons":"3.9","Gastric mucus-secreting cells":"2.4","Inhibitory neurons":"3.1","Oligodendrocyte precursor cells":"2.4","Oligodendrocytes":"2.2","Plasma cells":"7.7","Squamous epithelial cells":"7.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038873","HPA056195"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA038873":"AB_10673480","HPA056195":"AB_2683063"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NDUFS2","Gene synonym":["CI-49"],"Ensembl":"ENSG00000158864","Gene description":"NADH:ubiquinone oxidoreductase core subunit S2","Uniprot":["O75306"],"Chromosome":"1","Position":"161197104-161214723","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Oxidoreductase","Translocase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"464.8","tongue":"633.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055140","HPA061953"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"25000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA055140":"AB_2682713","HPA061953":"AB_2684646"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"}},{"Gene":"NDUFS7","Gene synonym":["CI-20","FLJ45860","FLJ46880","PSST"],"Ensembl":"ENSG00000115286","Gene description":"NADH:ubiquinone oxidoreductase core subunit S7","Uniprot":["O75251"],"Chromosome":"19","Position":"1383527-1395589","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":["Oxidoreductase","Translocase"],"Disease involvement":["Disease variant","Leigh syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"665.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"730.8","Proximal tubular cells":"765.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.03e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.90e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"}},{"Gene":"NECTIN1","Gene synonym":["CD111","CLPED1","ED4","HIgR","HVEC","OFC7","PRR","PRR1","PVRL1","PVRR1","SK-12"],"Ensembl":"ENSG00000110400","Gene description":"Nectin cell adhesion molecule 1","Uniprot":["Q15223"],"Chromosome":"11","Position":"119623408-119729200","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"128.8","skin 1":"134.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"90.0","Granulosa cells":"67.1","Squamous epithelial cells":"110.7","Suprabasal keratinocytes":"154.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"127.5"},"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016135","HPA026846"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016135":"AB_626865","HPA026846":"AB_1846226"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"}},{"Gene":"NECTIN2","Gene synonym":["CD112","HVEB","PRR2","PVRL2","PVRR2"],"Ensembl":"ENSG00000130202","Gene description":"Nectin cell adhesion molecule 2","Uniprot":["Q92692"],"Chromosome":"19","Position":"44846175-44889223","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"254.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"10.4"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"granulocytes":"10.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Colon - Endothelial cells","Skeletal muscle - Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012759","CAB026138","HPA073459"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5900000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoli fibrillar center","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB026138":null,"HPA012759":"AB_1846227","HPA073459":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"}},{"Gene":"NECTIN3","Gene synonym":["CD113","CDw113","DKFZP566B0846","nectin-3","PPR3","PVRL3","PVRR3"],"Ensembl":"ENSG00000177707","Gene description":"Nectin cell adhesion molecule 3","Uniprot":["Q9NQS3"],"Chromosome":"3","Position":"111070071-111275563","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"54.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"182.6","Excitatory neurons":"218.3","Late spermatids":"231.8","Oligodendrocyte precursor cells":"157.4","Syncytiotrophoblasts":"160.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009869","HPA011038"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"41000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cell Junctions","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009869":"AB_2284699","HPA011038":"AB_1079719"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.82e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"NECTIN4","Gene synonym":["LNIR","nectin-4","PRR4","PVRL4"],"Ensembl":"ENSG00000143217","Gene description":"Nectin cell adhesion molecule 4","Uniprot":["Q96NY8"],"Chromosome":"1","Position":"161070998-161089558","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"98.9","skin 1":"113.6","vagina":"57.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ionocytes":"90.9","Squamous epithelial cells":"111.1","Suprabasal keratinocytes":"185.4","Syncytiotrophoblasts":"467.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"29.0"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010775"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted in other tissues","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA010775":"AB_1079720"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"}},{"Gene":"NEGR1","Gene synonym":["IGLON4","KILON","MGC46680","Ntra"],"Ensembl":"ENSG00000172260","Gene description":"Neuronal growth regulator 1","Uniprot":["Q7Z3B1"],"Chromosome":"1","Position":"71395943-72282539","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"29.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1939.5","Inhibitory neurons":"1226.2","Oligodendrocyte precursor cells":"695.6","Oligodendrocytes":"417.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Kidney - Fibroblasts","Lung - Fibroblast_1","Pancreas - Fibroblasts","Prostate - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011894"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"380000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles","Actin filaments","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA011894":"AB_1854363"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-4"}},{"Gene":"NELFA","Gene synonym":["NELF-A","WHSC2"],"Ensembl":"ENSG00000185049","Gene description":"Negative elongation factor complex member A","Uniprot":["Q9H3P2"],"Chromosome":"4","Position":"1982717-2041903","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009960","HPA039858","HPA043931"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB009960":"AB_2288566","HPA039858":"AB_2676711","HPA043931":"AB_2678737"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.35e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"}},{"Gene":"NELFB","Gene synonym":["COBRA1","KIAA1182","NELF-B"],"Ensembl":"ENSG00000188986","Gene description":"Negative elongation factor complex member B","Uniprot":[],"Chromosome":"9","Position":"137255327-137273542","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020259"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA020259":"AB_1847072"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.31e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"}},{"Gene":"NELL2","Gene synonym":["NRP2"],"Ensembl":"ENSG00000184613","Gene description":"Neural EGFL like 2","Uniprot":["Q99435"],"Chromosome":"12","Position":"44508275-44921848","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"105.5","choroid plexus":"59.5","fallopian tube":"60.1","retina":"85.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"642.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"33.3"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"15","RNA brain regional specific nTPM":{"amygdala":"48.9","basal ganglia":"60.0","cerebral cortex":"105.5","hippocampal formation":"89.6","white matter":"42.0"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"70.4","naive CD8 T-cell":"111.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"T-cells":"111.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bone cancer":"139.8","Neuroblastoma":"54.7"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enteroendocrine cells","Lung - Respiratory ciliated cells","Skin - Outer root sheath cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035714","HPA035715"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6400000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035714":"AB_2674746","HPA035715":"AB_10669602"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.56e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"}},{"Gene":"NEMP1","Gene synonym":["KIAA0286","TMEM194","TMEM194A"],"Ensembl":"ENSG00000166881","Gene description":"Nuclear envelope integral membrane protein 1","Uniprot":["O14524"],"Chromosome":"12","Position":"57055643-57088063","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"40.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014394"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA014394":"AB_2204899"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.93e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"}},{"Gene":"NEMP2","Gene synonym":["TMEM194B"],"Ensembl":"ENSG00000189362","Gene description":"Nuclear envelope integral membrane protein 2","Uniprot":["A6NFY4"],"Chromosome":"2","Position":"190504338-190534722","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"17.1","Oligodendrocyte precursor cells":"27.0","Oligodendrocytes":"22.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057719"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA057719":"AB_2683510"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"NEO1","Gene synonym":["HsT17534","IGDCC2","NGN","NTN1R2"],"Ensembl":"ENSG00000067141","Gene description":"Neogenin 1","Uniprot":["Q92859"],"Chromosome":"15","Position":"73051710-73305205","Protein class":["Cancer-related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"224.6","Excitatory neurons":"122.7","Oligodendrocyte precursor cells":"115.0","Oligodendrocytes":"414.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009320","HPA027804","HPA027805","HPA027806"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"390000000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB009320":"AB_2150998","HPA027804":"AB_10600771","HPA027805":"AB_10601755","HPA027806":"AB_10601006"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"}},{"Gene":"NEPRO","Gene synonym":["C3orf17","DKFZP434F2021","NET17"],"Ensembl":"ENSG00000163608","Gene description":"Nucleolus and neural progenitor protein","Uniprot":["Q6NW34"],"Chromosome":"3","Position":"113002444-113019861","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069654"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA069654":"AB_2686164"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"}},{"Gene":"NETO1","Gene synonym":["BCTL1","BTCL1"],"Ensembl":"ENSG00000166342","Gene description":"Neuropilin and tolloid like 1","Uniprot":["Q8TDF5"],"Chromosome":"18","Position":"72742314-72868146","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"21.9","retina":"34.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Bipolar cells":"220.2","Excitatory neurons":"302.5","Inhibitory neurons":"337.1","Oligodendrocyte precursor cells":"165.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.2"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"41","RNA brain regional specific nTPM":{"amygdala":"6.6","basal ganglia":"12.4","cerebral cortex":"21.9","hippocampal formation":"17.5","white matter":"16.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"prostate cancer":"48.9"},"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064630"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA064630":"AB_2685305"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-3"}},{"Gene":"NETO2","Gene synonym":["FLJ10430","NEOT2"],"Ensembl":"ENSG00000171208","Gene description":"Neuropilin and tolloid like 2","Uniprot":["Q8NC67"],"Chromosome":"16","Position":"47077703-47143945","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"19.8","lymphoid tissue":"22.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"95.1","Inhibitory neurons":"172.1","Oligodendrocyte precursor cells":"76.1","Theca cells":"73.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013180"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA013180":"AB_1854383"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.53e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"NEU1","Gene synonym":["NEU"],"Ensembl":"ENSG00000204386","Gene description":"Neuraminidase 1","Uniprot":["Q99519"],"Chromosome":"6","Position":"31857659-31862905","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Lipid degradation","Lipid metabolism"],"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"243.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"3.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"3.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015634","HPA021506"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA015634":"AB_1854386","HPA021506":"AB_1854385"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"}},{"Gene":"NEURL3","Gene synonym":["Lincr","LOC93082","RNF132"],"Ensembl":"ENSG00000163121","Gene description":"Neuralized E3 ubiquitin protein ligase 3","Uniprot":["Q96EH8"],"Chromosome":"2","Position":"96497646-96508109","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"kidney":"16.2","pancreas":"25.1","salivary gland":"30.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"22.1","Collecting duct cells":"25.6","Ductal cells":"109.1","Exocrine glandular cells":"46.4","Ionocytes":"27.3","Pancreatic endocrine cells":"24.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Uterine cancer":"8.6"},"RNA tissue cell type enrichment":["Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.46e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-4"}},{"Gene":"NF1","Gene synonym":[],"Ensembl":"ENSG00000196712","Gene description":"Neurofibromin 1","Uniprot":["P21359"],"Chromosome":"17","Position":"31094927-31382116","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"246.1","Excitatory neurons":"320.6","Inhibitory neurons":"403.2","Oligodendrocyte precursor cells":"410.1","Oligodendrocytes":"299.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045502"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA045502":"AB_2679352"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"}},{"Gene":"NFAM1","Gene synonym":["CNAIP"],"Ensembl":"ENSG00000235568","Gene description":"NFAT activating protein with ITAM motif 1","Uniprot":["Q8NET5"],"Chromosome":"22","Position":"42380407-42432403","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"30.9","lymphoid tissue":"19.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hofbauer cells":"26.0","Kupffer cells":"68.0","Macrophages":"32.4","monocytes":"51.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"90.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"90.4","monocytes":"48.2"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Leukemia":"5.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Liver - Kupffer cells","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031812"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA031812":"AB_10603121"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.16e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"}},{"Gene":"NFASC","Gene synonym":["FLJ46866","KIAA0756","NF","NRCAML"],"Ensembl":"ENSG00000163531","Gene description":"Neurofascin","Uniprot":["O94856"],"Chromosome":"1","Position":"204828651-205022822","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"50.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"138.1","Excitatory neurons":"146.3","Horizontal cells":"206.4","Inhibitory neurons":"135.8","Oligodendrocyte precursor cells":"84.2","Oligodendrocytes":"213.9","Rod photoreceptor cells":"194.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"8.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008832"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2200000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008832":"AB_1854411"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.21e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.93e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"}},{"Gene":"NFIA","Gene synonym":["KIAA1439","NFI-L"],"Ensembl":"ENSG00000162599","Gene description":"Nuclear factor I A","Uniprot":["Q12857"],"Chromosome":"1","Position":"60865259-61462788","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["DNA replication","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"75.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"753.1","Oligodendrocyte precursor cells":"581.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Liver - Hepatocytes","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006111","HPA008884"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA006111":"AB_1854422","HPA008884":"AB_1854421"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.30e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.03e-4"}},{"Gene":"NFXL1","Gene synonym":["HOZFP"],"Ensembl":"ENSG00000170448","Gene description":"Nuclear transcription factor, X-box binding like 1","Uniprot":["Q6ZNB6"],"Chromosome":"4","Position":"47847233-47914667","Protein class":["Predicted membrane proteins","Transcription factors"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"76.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059132"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA059132":"AB_2683917"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.28e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"}},{"Gene":"NGFR","Gene synonym":["CD271","p75NTR","TNFRSF16"],"Ensembl":"ENSG00000064300","Gene description":"Nerve growth factor receptor","Uniprot":["P08138"],"Chromosome":"17","Position":"49495293-49515008","Protein class":["Cancer-related genes","CD markers","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Apoptosis","Biological rhythms","Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"63.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"48.2","Leydig cells":"92.9","Muller glia cells":"145.2","Sertoli cells":"30.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"plasmacytoid DC":"1.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"1.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"37.9","head and neck cancer":"37.6","Sarcoma":"79.3","skin cancer":"145.2"},"RNA tissue cell type enrichment":["Lung - Fibroblast_2","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"10.1"},"Antibody":["CAB000143","CAB001995","HPA004765"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"490000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB000143":null,"CAB001995":null,"HPA004765":"AB_1079233"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.40e-4"}},{"Gene":"NGLY1","Gene synonym":["FLJ11005","PNG-1","PNG1"],"Ensembl":"ENSG00000151092","Gene description":"N-glycanase 1","Uniprot":["Q96IV0"],"Chromosome":"3","Position":"25718944-25790039","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"427.3","Late spermatids":"1054.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036825"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036825":"AB_10672231"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.17e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.96e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"}},{"Gene":"NID1","Gene synonym":["entactin","NID"],"Ensembl":"ENSG00000116962","Gene description":"Nidogen 1","Uniprot":["P14543"],"Chromosome":"1","Position":"235975830-236065109","Protein class":["Plasma proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"230.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"353.2","Fibroblasts":"209.6","Leydig cells":"172.0","Peritubular cells":"124.2","Sertoli cells":"105.0","Smooth muscle cells":"103.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"classical monocyte":"5.7","intermediate monocyte":"11.2","myeloid DC":"4.4","non-classical monocyte":"7.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"dendritic cells":"4.4","monocytes":"11.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"104.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010044","HPA065049"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Mitotic spindle"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Mitotic spindle"],"Antibody RRID":{"CAB010044":"AB_2153287","HPA065049":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.38e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-3"}},{"Gene":"NID2","Gene synonym":[],"Ensembl":"ENSG00000087303","Gene description":"Nidogen 2","Uniprot":["Q14112"],"Chromosome":"14","Position":"52004803-52069228","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"60.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"26.0","Fibroblasts":"43.4","Microglial cells":"19.2","Smooth muscle cells":"23.2","Theca cells":"33.9","Thymic epithelial cells":"24.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"15.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"57.2"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052460","HPA058772"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6300000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA052460":"AB_2681840","HPA058772":"AB_2683815"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.34e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-4"}},{"Gene":"NIF3L1","Gene synonym":["ALS2CR1","CALS-7","MDS015"],"Ensembl":"ENSG00000196290","Gene description":"NGG1 interacting factor 3 like 1","Uniprot":["Q9GZT8"],"Chromosome":"2","Position":"200889327-200903938","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"60.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036335","HPA036336","HPA061466"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9800000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036335":"AB_10696654","HPA036336":"AB_2675068","HPA061466":"AB_2684532"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.52e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.51e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"}},{"Gene":"NIM1K","Gene synonym":["MGC42105","NIM1"],"Ensembl":"ENSG00000177453","Gene description":"NIM1 serine\/threonine protein kinase","Uniprot":["Q8IY84"],"Chromosome":"5","Position":"43192071-43280850","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"13.7","choroid plexus":"7.9","pituitary gland":"6.5","retina":"10.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"28.8","Cone photoreceptor cells":"36.2","Excitatory neurons":"55.2","Inhibitory neurons":"43.3","Oligodendrocyte precursor cells":"41.9","Oligodendrocytes":"19.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"6.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"1.7"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007695"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007695":"AB_2667897"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-3"}},{"Gene":"NINJ1","Gene synonym":["NIN1"],"Ensembl":"ENSG00000131669","Gene description":"Ninjurin 1","Uniprot":["Q92982"],"Chromosome":"9","Position":"93121496-93134251","Protein class":["Predicted membrane proteins"],"Biological process":["Angiogenesis","Cell adhesion","Cytolysis","Inflammatory response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"286.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"589.4","Langerhans cells":"856.0","monocytes":"329.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1668.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1668.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045063"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045063":"AB_10964133"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-3"}},{"Gene":"NINJ2","Gene synonym":[],"Ensembl":"ENSG00000171840","Gene description":"Ninjurin 2","Uniprot":["Q9NZG7"],"Chromosome":"12","Position":"564296-663779","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"45.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"27.9","Erythroid cells":"28.8","Hofbauer cells":"36.5","Oligodendrocytes":"103.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"cervical cancer":"26.0","Leukemia":"25.7","lymphoma":"15.6"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058980","HPA067226"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA058980":"AB_2683869","HPA067226":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.31e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"NIPA1","Gene synonym":["MGC35570","SLC57A1","SPG6"],"Ensembl":"ENSG00000170113","Gene description":"NIPA magnesium transporter 1","Uniprot":["Q7RTP0"],"Chromosome":"15","Position":"22773063-22829789","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"40.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"35.7","Inhibitory neurons":"33.0","Oligodendrocytes":"61.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"3.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023269"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023269":"AB_1854485"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"}},{"Gene":"NIPA2","Gene synonym":["SLC57A2"],"Ensembl":"ENSG00000140157","Gene description":"NIPA magnesium transporter 2","Uniprot":["Q8N8Q9"],"Chromosome":"15","Position":"22838644-22869362","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067160","HPA071342"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA067160":"AB_2685794","HPA071342":"AB_2686391"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"}},{"Gene":"NIPAL1","Gene synonym":["DKFZp686A06115","NPAL1"],"Ensembl":"ENSG00000163293","Gene description":"NIPA like domain containing 1","Uniprot":["Q6NVV3"],"Chromosome":"4","Position":"47914142-48040173","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"21.8","skin 1":"25.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"39.4","Distal enterocytes":"49.6","Paneth cells":"38.4","Squamous epithelial cells":"52.6","Suprabasal keratinocytes":"77.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Liver - Hepatocytes","Pancreas - Ductal cells","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036765"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA036765":"AB_10672366"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"}},{"Gene":"NIPAL2","Gene synonym":["FLJ13955","NPAL2"],"Ensembl":"ENSG00000104361","Gene description":"NIPA like domain containing 2","Uniprot":["Q9H841"],"Chromosome":"8","Position":"98189826-98294393","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"123.0","Squamous epithelial cells":"61.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071759"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA071759":"AB_2686443"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"}},{"Gene":"NIPAL3","Gene synonym":["DJ462O23.2","NPAL3"],"Ensembl":"ENSG00000001461","Gene description":"NIPA like domain containing 3","Uniprot":["Q6P499"],"Chromosome":"1","Position":"24415802-24472976","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"88.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"100.0","Oligodendrocytes":"86.7","Prostatic glandular cells":"195.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Prostate - Prostate glandular cells","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039978"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA039978":"AB_10697712"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.03e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.95e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"}},{"Gene":"NIPAL4","Gene synonym":["ICHYN"],"Ensembl":"ENSG00000172548","Gene description":"NIPA like domain containing 4","Uniprot":["Q0D2K0"],"Chromosome":"5","Position":"157460213-157474722","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.7","skin 1":"61.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"24.1","Oligodendrocytes":"19.8","Squamous epithelial cells":"9.0","Suprabasal keratinocytes":"37.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"17.0","urothelial cancer":"11.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"25","RNA blood cell specific nTPM":{"memory B-cell":"1.6","naive B-cell":"4.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"37","RNA blood lineage specific nTPM":{"B-cells":"4.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"10.7","head and neck cancer":"12.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038259"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038259":"AB_10672510"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.82e-4"}},{"Gene":"NIPBL","Gene synonym":["DKFZp434L1319","FLJ11203","FLJ12597","FLJ13354","FLJ13648","IDN3","Scc2"],"Ensembl":"ENSG00000164190","Gene description":"NIPBL cohesin loading factor","Uniprot":["Q6KC79"],"Chromosome":"5","Position":"36876769-37066413","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040834","HPA058239"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA040834":"AB_10796562","HPA058239":"AB_2683650"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"}},{"Gene":"NKAIN1","Gene synonym":["FAM77C","FLJ12650"],"Ensembl":"ENSG00000084628","Gene description":"Sodium\/potassium transporting ATPase interacting 1","Uniprot":["Q4KMZ8"],"Chromosome":"1","Position":"31179745-31239887","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"24.2","brain":"19.9","skeletal muscle":"19.4","tongue":"11.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Oligodendrocytes":"41.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"breast cancer":"17.2","glioma":"4.6","prostate cancer":"10.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"26.7"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006873"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA006873":"AB_1848410"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"}},{"Gene":"NKAIN2","Gene synonym":["FAM77B","TCBA1"],"Ensembl":"ENSG00000188580","Gene description":"Sodium\/potassium transporting ATPase interacting 2","Uniprot":["Q5VXU1"],"Chromosome":"6","Position":"123803865-124825640","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"56.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1696.5","Inhibitory neurons":"621.4","Oligodendrocytes":"2708.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"basophil":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"granulocytes":"1.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"3.9","thyroid cancer":"6.7"},"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045860"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA045860":"AB_10983192"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"}},{"Gene":"NKAIN3","Gene synonym":["FAM77D","FLJ39630","NKAIN3-IT1"],"Ensembl":"ENSG00000185942","Gene description":"Sodium\/potassium transporting ATPase interacting 3","Uniprot":["Q8N8D7"],"Chromosome":"8","Position":"62248591-63014000","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"18.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"1219.4","Oligodendrocyte precursor cells":"777.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018833"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018833":"AB_2669943"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"}},{"Gene":"NKAIN4","Gene synonym":["bA261N11.2","C20orf58","FAM77A"],"Ensembl":"ENSG00000101198","Gene description":"Sodium\/potassium transporting ATPase interacting 4","Uniprot":["Q8IVV8"],"Chromosome":"20","Position":"63240784-63272694","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"brain":"68.1","choroid plexus":"20.3","kidney":"52.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal tubular cells":"336.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"45.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"29.5","Uterine cancer":"16.5"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029876"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029876":"AB_10602038"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.14e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"}},{"Gene":"NKG7","Gene synonym":["GIG1","GMP-17"],"Ensembl":"ENSG00000105374","Gene description":"Natural killer cell granule protein 7","Uniprot":["Q16617"],"Chromosome":"19","Position":"51371606-51372701","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cytolysis","Inflammatory response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"bone marrow":"602.6","lymphoid tissue":"154.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"NK-cells":"6101.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"6827.0","MAIT T-cell":"2871.2","memory CD8 T-cell":"4295.0","naive CD8 T-cell":"3114.2","NK-cell":"4796.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"44","RNA blood lineage specific nTPM":{"NK-cells":"4796.8","T-cells":"6827.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"26","RNA cell line specific nTPM":{"Leukemia":"62.9","lymphoma":"64.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - NK-cells (Liver)","Lung - NK-cells (Lung)","Prostate - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071454"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA071454":"AB_2686399"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.42e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.32e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-3"}},{"Gene":"NKIRAS2","Gene synonym":["DKFZP434N1526","kappaB-Ras2","KBRAS2"],"Ensembl":"ENSG00000168256","Gene description":"NFKB inhibitor interacting Ras like 2","Uniprot":["Q9NYR9"],"Chromosome":"17","Position":"42011382-42025644","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062861"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA062861":"AB_2684884"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.56e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"}},{"Gene":"NKPD1","Gene synonym":["FLJ33600"],"Ensembl":"ENSG00000179846","Gene description":"NTPase KAP family P-loop domain containing 1","Uniprot":["Q17RQ9"],"Chromosome":"19","Position":"45149750-45160815","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"15.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"2.2","Basal prostatic cells":"1.5","Horizontal cells":"2.6","Spermatocytes":"2.0","Suprabasal keratinocytes":"3.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043339"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043339":"AB_10962493"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"}},{"Gene":"NLGN1","Gene synonym":["KIAA1070"],"Ensembl":"ENSG00000169760","Gene description":"Neuroligin 1","Uniprot":["Q8N2Q7"],"Chromosome":"3","Position":"173396284-174286644","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Biological rhythms","Cell adhesion"],"Molecular function":null,"Disease involvement":["Autism","Autism spectrum disorder","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"31.0","retina":"13.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"31","RNA single cell type specific nTPM":{"Excitatory neurons":"1462.4","Inhibitory neurons":"1658.7","Oligodendrocyte precursor cells":"3834.4","Oligodendrocytes":"1191.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"3.8","melanoma":"2.2","renal cancer":"3.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"14.1"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006572","HPA006680","CAB033261"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear bodies","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"82000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB033261":"AB_2151659","HPA006572":null,"HPA006680":"AB_1854400"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"}},{"Gene":"NLGN2","Gene synonym":["KIAA1366"],"Ensembl":"ENSG00000169992","Gene description":"Neuroligin 2","Uniprot":["Q8NFZ4"],"Chromosome":"17","Position":"7404874-7419860","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"25.0","Bipolar cells":"25.1","Endometrial stromal cells":"23.9","Horizontal cells":"29.5","Inhibitory neurons":"24.2","Oligodendrocyte precursor cells":"43.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055321","HPA069278"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA055321":"AB_2682783","HPA069278":"AB_2686105"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"}},{"Gene":"NLGN3","Gene synonym":["ASPGX1","AUTSX1","HNL3","KIAA1480"],"Ensembl":"ENSG00000196338","Gene description":"Neuroligin 3","Uniprot":["Q9NZ94"],"Chromosome":"X","Position":"71144831-71171201","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Asperger syndrome","Autism","Autism spectrum disorder","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.1","seminal vesicle":"12.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"19.0","Inhibitory neurons":"12.4","Oligodendrocyte precursor cells":"88.1","Oligodendrocytes":"41.2","Peritubular cells":"16.6","Schwann cells":"17.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"19","RNA cancer specific FPKM":{"glioma":"37.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"5.5"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Testis - Peritubular cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003183","HPA004066"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Golgi apparatus","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA003183":"AB_1079469","HPA004066":"AB_2732397"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"}},{"Gene":"NLGN4X","Gene synonym":["HLNX","KIAA1260","NLGN","NLGN4"],"Ensembl":"ENSG00000146938","Gene description":"Neuroligin 4 X-linked","Uniprot":["Q8N0W4"],"Chromosome":"X","Position":"5840637-6228867","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Asperger syndrome","Autism","Autism spectrum disorder"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"28.5","lymphoid tissue":"14.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"110.4","Excitatory neurons":"159.8","Inhibitory neurons":"231.4","Oligodendrocyte precursor cells":"672.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"endometrial cancer":"2.7","glioma":"8.5","testis cancer":"3.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"23.5","testis cancer":"42.7"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Liver - Hepatic stellate cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001651"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001651":"AB_1079470"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"}},{"Gene":"NLGN4Y","Gene synonym":["KIAA0951"],"Ensembl":"ENSG00000165246","Gene description":"Neuroligin 4 Y-linked","Uniprot":["Q8NFZ3"],"Chromosome":"Y","Position":"14522573-14845650","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"6.3","seminal vesicle":"7.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"46.5","Excitatory neurons":"144.0","Inhibitory neurons":"105.4","Oligodendrocyte precursor cells":"211.3","Oligodendrocytes":"44.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"testis cancer":"19.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001651"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001651":"AB_1079470"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"}},{"Gene":"NLK","Gene synonym":[],"Ensembl":"ENSG00000087095","Gene description":"Nemo like kinase","Uniprot":["Q9UBE8"],"Chromosome":"17","Position":"28041737-28196381","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"78.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"126.8","Excitatory neurons":"311.3","Late spermatids":"415.0","Oligodendrocytes":"346.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"45","RNA blood cell specific nTPM":{"basophil":"29.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"45","RNA blood lineage specific nTPM":{"granulocytes":"29.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018192","HPA056511"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Cell Junctions"],"Antibody RRID":{"HPA018192":"AB_1854525","HPA056511":"AB_2683160"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"}},{"Gene":"NMBR","Gene synonym":["BB1","BB1R"],"Ensembl":"ENSG00000135577","Gene description":"Neuromedin B receptor","Uniprot":["P28336"],"Chromosome":"6","Position":"142058330-142088799","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.5","testis":"1.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"3.2","Early spermatids":"8.3","Excitatory neurons":"2.3","Inhibitory neurons":"4.4","Oligodendrocyte precursor cells":"1.9","Oligodendrocytes":"2.4","Spermatocytes":"2.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026665"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA026665":"AB_1854527"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"}},{"Gene":"NMRAL1","Gene synonym":["FLJ25918","HSCARG","SDR48A1"],"Ensembl":"ENSG00000153406","Gene description":"NmrA like redox sensor 1","Uniprot":["Q9HBL8"],"Chromosome":"16","Position":"4461691-4495763","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041353","HPA062287"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA041353":"AB_10796343","HPA062287":"AB_2684738"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.33e-7"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"}},{"Gene":"NMUR1","Gene synonym":["FM-3","GPC-R","GPR66","NMU1R"],"Ensembl":"ENSG00000171596","Gene description":"Neuromedin U receptor 1","Uniprot":["Q9HB89"],"Chromosome":"2","Position":"231523187-231530445","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"8.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"32.6","Peritubular cells":"7.7","Rod photoreceptor cells":"17.8","T-cells":"6.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.1"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"gdT-cell":"18.1","MAIT T-cell":"4.6","memory CD8 T-cell":"8.8","naive CD8 T-cell":"5.2","NK-cell":"10.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"NK-cells":"10.9","T-cells":"18.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.9"},"RNA tissue cell type enrichment":["Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027895"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027895":"AB_10602713"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"}},{"Gene":"NMUR2","Gene synonym":["NMU2R"],"Ensembl":"ENSG00000132911","Gene description":"Neuromedin U receptor 2","Uniprot":["Q9GZQ4"],"Chromosome":"5","Position":"152391546-152433368","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"6.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"3.6","Oligodendrocytes":"8.0","Sertoli cells":"2.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"1.8","stomach cancer":"2.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"2.7","pancreatic cancer":"8.0"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"1.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027800","HPA045836"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA027800":null,"HPA045836":"AB_10968856"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"}},{"Gene":"NNAT","Gene synonym":["Peg5"],"Ensembl":"ENSG00000053438","Gene description":"Neuronatin","Uniprot":["Q16517"],"Chromosome":"20","Position":"37521206-37523690","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"pituitary gland":"1586.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"33.4","Late spermatids":"83.4","Muller glia cells":"144.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"16","RNA cancer specific FPKM":{"glioma":"87.5","testis cancer":"55.0","urothelial cancer":"37.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"168.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.66e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"}},{"Gene":"NNT","Gene synonym":[],"Ensembl":"ENSG00000112992","Gene description":"Nicotinamide nucleotide transhydrogenase","Uniprot":["Q13423"],"Chromosome":"5","Position":"43602692-43707405","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Translocase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"239.1","tongue":"384.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"472.8","Hepatocytes":"365.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Skeletal muscle - Skeletal myocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004829","CAB004975","HPA066564"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB004975":"AB_425908","HPA004829":"AB_1079495","HPA066564":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.22e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"}},{"Gene":"NOBOX","Gene synonym":["OG2","Og2x"],"Ensembl":"ENSG00000106410","Gene description":"NOBOX oogenesis homeobox","Uniprot":["O60393"],"Chromosome":"7","Position":"144397240-144410227","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Oogenesis","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Disease variant","Premature ovarian failure"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"0.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NOC4L","Gene synonym":["MGC3162","NET49","Noc4","UTP19"],"Ensembl":"ENSG00000184967","Gene description":"Nucleolar complex associated 4 homolog","Uniprot":["Q9BVI4"],"Chromosome":"12","Position":"132144457-132152473","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"87.4","Spermatogonia":"87.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053424"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 47: Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA053424":"AB_2682147"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"}},{"Gene":"NOL11","Gene synonym":["DKFZP586L0724"],"Ensembl":"ENSG00000130935","Gene description":"Nucleolar protein 11","Uniprot":["Q9H8H0"],"Chromosome":"17","Position":"67717931-67744531","Protein class":["Predicted intracellular proteins"],"Biological process":["Ribosome biogenesis","rRNA processing","Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022010"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA022010":"AB_2267158"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.00e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.59e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"}},{"Gene":"NOMO1","Gene synonym":["PM5"],"Ensembl":"ENSG00000103512","Gene description":"NODAL modulator 1","Uniprot":["Q15155"],"Chromosome":"16","Position":"14833721-14896157","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"133.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"36.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"3.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025192","HPA046697","HPA061174"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB025192":null,"HPA046697":"AB_2679758","HPA061174":"AB_2684444"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.15e-4"}},{"Gene":"NOMO2","Gene synonym":["NOMO","PM5"],"Ensembl":"ENSG00000185164","Gene description":"NODAL modulator 2","Uniprot":["Q5JPE7"],"Chromosome":"16","Position":"18417325-18562211","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"300.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"6.3","Oligodendrocyte precursor cells":"8.2","Oligodendrocytes":"7.2","Plasma cells":"21.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046697","HPA061174"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046697":"AB_2679758","HPA061174":"AB_2684444"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"NOMO3","Gene synonym":[],"Ensembl":"ENSG00000103226","Gene description":"NODAL modulator 3","Uniprot":["P69849"],"Chromosome":"16","Position":"16232506-16300806","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"30.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"22.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046697","HPA061174"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046697":"AB_2679758","HPA061174":"AB_2684444"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"}},{"Gene":"NOP56","Gene synonym":["NOL5A","SCA36"],"Ensembl":"ENSG00000101361","Gene description":"NOP56 ribonucleoprotein","Uniprot":["O00567"],"Chromosome":"20","Position":"2652593-2658393","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Ribosome biogenesis"],"Molecular function":["Ribonucleoprotein"],"Disease involvement":["Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049918","CAB075757"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"CAB075757":"AB_2665763","HPA049918":"AB_2680952"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.77e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.22e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"}},{"Gene":"NOS1","Gene synonym":["nNOS","NOS"],"Ensembl":"ENSG00000089250","Gene description":"Nitric oxide synthase 1","Uniprot":["P29475"],"Chromosome":"12","Position":"117208142-117452170","Protein class":["Cancer-related genes","Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Oxidoreductase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"23.0","skeletal muscle":"36.9","tongue":"57.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"31.3","Oligodendrocyte precursor cells":"46.2","Salivary duct cells":"22.5","Skeletal myocytes":"8.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"3.8"},"RNA tissue cell type enrichment":["Adipose visceral - Smooth muscle cells","Colon - Colon enteroendocrine cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002167","HPA058312","HPA069509"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB002167":"AB_564073","HPA058312":"AB_2683676","HPA069509":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"}},{"Gene":"NOS3","Gene synonym":["ECNOS","eNOS"],"Ensembl":"ENSG00000164867","Gene description":"Nitric oxide synthase 3","Uniprot":["P29474"],"Chromosome":"7","Position":"150991017-151014588","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Oxidoreductase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"62.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"19.1","Early spermatids":"86.3","Endothelial cells":"25.7","Late spermatids":"34.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"2.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002168"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002168":"AB_564072"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"}},{"Gene":"NOSTRIN","Gene synonym":["MGC20702"],"Ensembl":"ENSG00000163072","Gene description":"Nitric oxide synthase trafficking","Uniprot":["Q8IVI9"],"Chromosome":"2","Position":"168786539-168865514","Protein class":["Predicted intracellular proteins"],"Biological process":["Endocytosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"153.0","Endothelial cells":"151.7","Serous glandular cells":"91.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"9.3","Gastric cancer":"10.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044384","HPA076885"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA044384":"AB_2678922","HPA076885":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"}},{"Gene":"NOTCH1","Gene synonym":["TAN1"],"Ensembl":"ENSG00000148400","Gene description":"Notch receptor 1","Uniprot":["P46531"],"Chromosome":"9","Position":"136494433-136546048","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis","Differentiation","Notch signaling pathway","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"54.6","Astrocytes":"65.2","Endothelial cells":"60.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Kidney - Endothelial cells","Skeletal muscle - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008112","CAB022466","HPA067168"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB008112":"AB_2153490","CAB022466":null,"HPA067168":"AB_2685795"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"}},{"Gene":"NOTCH2","Gene synonym":[],"Ensembl":"ENSG00000134250","Gene description":"Notch receptor 2","Uniprot":["Q04721"],"Chromosome":"1","Position":"119911553-120100779","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Notch signaling pathway","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"139.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048743"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA048743":"AB_2680508"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.24e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.48e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-3"}},{"Gene":"NOTCH3","Gene synonym":["CADASIL","CASIL"],"Ensembl":"ENSG00000074181","Gene description":"Notch receptor 3","Uniprot":["Q9UM47"],"Chromosome":"19","Position":"15159038-15200995","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Notch signaling pathway","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Sertoli cells":"179.7","Smooth muscle cells":"282.2","Squamous epithelial cells":"76.8","Suprabasal keratinocytes":"92.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"82.7"},"RNA tissue cell type enrichment":["Lung - Smooth muscle cells","Prostate - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005393","HPA044392"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"46000000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB005393":"AB_2151246","HPA044392":"AB_2678926"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.92e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"}},{"Gene":"NOTCH4","Gene synonym":["INT3"],"Ensembl":"ENSG00000204301","Gene description":"Notch receptor 4","Uniprot":["Q99466"],"Chromosome":"6","Position":"32194843-32224067","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":["Differentiation","Notch signaling pathway","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"24.2","breast":"19.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"248.1","Endothelial cells":"123.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Pancreas - Endothelial cells","Skin - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.84e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"}},{"Gene":"NOX1","Gene synonym":["GP91-2","MOX1","NOH-1","NOH1"],"Ensembl":"ENSG00000007952","Gene description":"NADPH oxidase 1","Uniprot":["Q9Y5S8"],"Chromosome":"X","Position":"100843324-100874359","Protein class":["Disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Ion transport","Transport"],"Molecular function":["Ion channel","Oxidoreductase","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"intestine":"71.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"44","RNA single cell type specific nTPM":{"Distal enterocytes":"63.8","Enteroendocrine cells":"34.5","Intestinal goblet cells":"28.7","Paneth cells":"27.4","Undifferentiated cells":"47.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"colorectal cancer":"82.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"colorectal cancer":"15.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.71e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-3"}},{"Gene":"NOX3","Gene synonym":["GP91-3"],"Ensembl":"ENSG00000074771","Gene description":"NADPH oxidase 3","Uniprot":["Q9HBY0"],"Chromosome":"6","Position":"155395368-155455839","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"1.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Rhabdoid":"9.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073837"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA073837":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NOX4","Gene synonym":["KOX","KOX-1"],"Ensembl":"ENSG00000086991","Gene description":"NADPH oxidase 4","Uniprot":["Q9NPH5"],"Chromosome":"11","Position":"89324353-89498187","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"kidney":"138.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal tubular cells":"133.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"5.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"7.1"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-3"}},{"Gene":"NOX5","Gene synonym":["NOX5A","NOX5B"],"Ensembl":"ENSG00000255346","Gene description":"NADPH oxidase 5","Uniprot":["Q96PH1"],"Chromosome":"15","Position":"68930525-69062762","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis","Electron transport","Ion transport","Transport"],"Molecular function":["Ion channel","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"8.8","testis":"2.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"15.3","Excitatory neurons":"6.3","Inhibitory neurons":"5.3","Late spermatids":"13.1","Theca cells":"11.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"1.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"}},{"Gene":"NPB","Gene synonym":["PPL7","PPNPB"],"Ensembl":"ENSG00000183979","Gene description":"Neuropeptide B","Uniprot":["Q8NG41"],"Chromosome":"17","Position":"81900745-81902905","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":["Neuropeptide"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"8.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Spermatogonia":"45.2","Syncytiotrophoblasts":"133.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"2.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-1"}},{"Gene":"NPBWR1","Gene synonym":["GPR7"],"Ensembl":"ENSG00000288611","Gene description":"Neuropeptides B and W receptor 1","Uniprot":["P48145"],"Chromosome":"8","Position":"52939182-52943734","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.6","liver":"2.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"1.9","Hepatocytes":"1.3","Salivary duct cells":"1.0"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NPBWR2","Gene synonym":["GPR8"],"Ensembl":"ENSG00000125522","Gene description":"Neuropeptides B and W receptor 2","Uniprot":["P48146"],"Chromosome":"20","Position":"64105820-64107171","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NPC1","Gene synonym":["SLC65A1"],"Ensembl":"ENSG00000141458","Gene description":"NPC intracellular cholesterol transporter 1","Uniprot":["O15118"],"Chromosome":"18","Position":"23506184-23586506","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cholesterol metabolism","Host-virus interaction","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant","Niemann-Pick disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"110.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"171.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"70.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026618","CAB070132","HPA077445"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB070132":"AB_10001101","HPA026618":"AB_1854580","HPA077445":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"}},{"Gene":"NPC1L1","Gene synonym":["SLC65A2"],"Ensembl":"ENSG00000015520","Gene description":"NPC1 like intracellular cholesterol transporter 1","Uniprot":["Q9UHC9"],"Chromosome":"7","Position":"44512535-44541330","Protein class":["FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"intestine":"54.2","liver":"48.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"33.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"8.5","pancreatic cancer":"7.8","stomach cancer":"4.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Gastric cancer":"9.0","liver cancer":"7.8"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB070127","CAB070128"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB070127":"AB_10002744","CAB070128":"AB_10000815"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"}},{"Gene":"NPDC1","Gene synonym":["CAB-","CAB1","DKFZp586J0523"],"Ensembl":"ENSG00000107281","Gene description":"Neural proliferation, differentiation and control 1","Uniprot":["Q9NQX5"],"Chromosome":"9","Position":"137039463-137046179","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"431.4","Endothelial cells":"301.2","Intestinal goblet cells":"570.6","Prostatic glandular cells":"366.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"146.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"12.3","MAIT T-cell":"14.7","memory CD4 T-cell":"19.0","memory CD8 T-cell":"18.9","T-reg":"15.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"19.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Prostate glandular cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008189"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA008189":"AB_1854584"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.01e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.19e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"}},{"Gene":"NPFFR1","Gene synonym":["GPR147","NPFF1R1","OT7T022"],"Ensembl":"ENSG00000148734","Gene description":"Neuropeptide FF receptor 1","Uniprot":["Q9GZQ6"],"Chromosome":"10","Position":"70247329-70284004","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"9.5","retina":"3.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"6.3","Muller glia cells":"8.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"1.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 2","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"basal ganglia":"15.7","hypothalamus":"6.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037521"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037521":"AB_2675520"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"NPFFR2","Gene synonym":["GPR74","NPFF2","NPGPR"],"Ensembl":"ENSG00000056291","Gene description":"Neuropeptide FF receptor 2","Uniprot":["Q9Y5X5"],"Chromosome":"4","Position":"72031804-72148067","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"7.2","seminal vesicle":"3.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"22.0","Cytotrophoblasts":"6.8","Excitatory neurons":"14.2","Extravillous trophoblasts":"13.8","Syncytiotrophoblasts":"10.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"14.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"olfactory bulb":"4.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026825"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA026825":"AB_10603123"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"}},{"Gene":"NPHP1","Gene synonym":["JBTS4","NPH1","SLSN1"],"Ensembl":"ENSG00000144061","Gene description":"Nephrocystin 1","Uniprot":["O15259"],"Chromosome":"2","Position":"110122311-110205066","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Joubert syndrome","Leber congenital amaurosis","Nephronophthisis","Senior-Loken syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"36.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"169.7","Endometrial ciliated cells":"144.5","Respiratory ciliated cells":"119.5","Rod photoreceptor cells":"75.9","Spermatocytes":"135.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Skeletal muscle - Skeletal myocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046093","HPA074071"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046093":"AB_2679535","HPA074071":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"}},{"Gene":"NPHP4","Gene synonym":["KIAA0673","POC10","SLSN4"],"Ensembl":"ENSG00000131697","Gene description":"Nephrocystin 4","Uniprot":["O75161"],"Chromosome":"1","Position":"5862811-5992473","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Leber congenital amaurosis","Nephronophthisis","Senior-Loken syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"23.4","Excitatory neurons":"46.4","Inhibitory neurons":"30.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"2.7","hippocampal formation":"3.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063852","HPA065526"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Nuclear bodies","Vesicles"],"Antibody RRID":{"HPA063852":null,"HPA065526":"AB_2685505"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"NPHS2","Gene synonym":["PDCN","SRN1"],"Ensembl":"ENSG00000116218","Gene description":"NPHS2 stomatin family member, podocin","Uniprot":["Q9NP85"],"Chromosome":"1","Position":"179550539-179575952","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"140","RNA tissue specific nTPM":{"kidney":"255.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Collecting duct cells":"35.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Podocytes","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037267","HPA049486"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037267":"AB_261982","HPA049486":"AB_2680788"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NPIPA1","Gene synonym":["morpheus","NPIP"],"Ensembl":"ENSG00000183426","Gene description":"Nuclear pore complex interacting protein family member A1","Uniprot":["Q9UND3"],"Chromosome":"16","Position":"14922802-14952060","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"938.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"27.8","Excitatory neurons":"37.2","Inhibitory neurons":"26.6","Late spermatids":"32.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"15","RNA brain regional specific nTPM":{"cerebral cortex":"938.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-5"}},{"Gene":"NPIPA2","Gene synonym":[],"Ensembl":"ENSG00000254852","Gene description":"Nuclear pore complex interacting protein family member A2","Uniprot":["E9PIF3"],"Chromosome":"16","Position":"14748066-14765413","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"2.8","Early spermatids":"3.3","Excitatory neurons":"2.1","Inhibitory neurons":"1.4","Late spermatids":"2.2","Oligodendrocytes":"1.7","Spermatocytes":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NPIPA3","Gene synonym":[],"Ensembl":"ENSG00000224712","Gene description":"Nuclear pore complex interacting protein family member A3","Uniprot":["F8WFD2"],"Chromosome":"16","Position":"14708944-14726338","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"2.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"}},{"Gene":"NPIPA5","Gene synonym":[],"Ensembl":"ENSG00000183793","Gene description":"Nuclear pore complex interacting protein family member A5","Uniprot":["E9PKD4"],"Chromosome":"16","Position":"15363628-15381047","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"8.5","Basal squamous epithelial cells":"7.6","Early spermatids":"15.1","Excitatory neurons":"10.1","Inhibitory neurons":"7.9","Late spermatids":"8.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"}},{"Gene":"NPIPA7","Gene synonym":[],"Ensembl":"ENSG00000214967","Gene description":"Nuclear pore complex interacting protein family member A7","Uniprot":["E9PJI5"],"Chromosome":"16","Position":"16379055-16393954","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NPIPA8","Gene synonym":["LCR16a9"],"Ensembl":"ENSG00000214940","Gene description":"Nuclear pore complex interacting protein family member A8","Uniprot":["P0DM63"],"Chromosome":"16","Position":"18317942-18336736","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"28.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"38.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NPIPA9","Gene synonym":[],"Ensembl":"ENSG00000233024","Gene description":"Nuclear pore complex interacting protein family, member A9","Uniprot":[],"Chromosome":"16","Position":"18358086-18379331","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Intestinal goblet cells":"1.1","Pancreatic endocrine cells":"1.7","Paneth cells":"1.6","Undifferentiated cells":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-3"}},{"Gene":"NPIPB11","Gene synonym":[],"Ensembl":"ENSG00000254206","Gene description":"Nuclear pore complex interacting protein family member B11","Uniprot":["E5RHQ5"],"Chromosome":"16","Position":"29381354-29404029","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"5.8","Early spermatids":"6.3","Enteroendocrine cells":"6.8","Inhibitory neurons":"5.3","Intestinal goblet cells":"5.6","Late spermatids":"9.1","Undifferentiated cells":"5.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-5"}},{"Gene":"NPIPB12","Gene synonym":[],"Ensembl":"ENSG00000169203","Gene description":"Nuclear pore complex interacting protein family member B12","Uniprot":["F8W0I5"],"Chromosome":"16","Position":"29483642-29505999","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"198.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"1.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"29.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"8.4","granulocytes":"29.3","NK-cells":"14.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-4"}},{"Gene":"NPIPB13","Gene synonym":[],"Ensembl":"ENSG00000198064","Gene description":"Nuclear pore complex interacting protein family, member B13","Uniprot":["A6NJU9"],"Chromosome":"16","Position":"30222937-30254510","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Intestinal goblet cells":"3.6","Late spermatids":"3.7","Melanocytes":"3.5","Microglial cells":"4.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"}},{"Gene":"NPIPB15","Gene synonym":["LOC440348","NPIPL2"],"Ensembl":"ENSG00000196436","Gene description":"Nuclear pore complex interacting protein family member B15","Uniprot":["A6NHN6"],"Chromosome":"16","Position":"74377878-74392080","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"55.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"271.7","Late spermatids":"225.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"5.6"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"1.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011188","HPA053611"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA011188":"AB_2668455","HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"}},{"Gene":"NPIPB2","Gene synonym":[],"Ensembl":"ENSG00000234719","Gene description":"Nuclear pore complex interacting protein family member B2","Uniprot":["A6NJ64"],"Chromosome":"16","Position":"11927259-11976643","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"15.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"49.7","Late spermatids":"64.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Myeloma":"13.4"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"}},{"Gene":"NPIPB3","Gene synonym":["KIAA0220","NPIPL3"],"Ensembl":"ENSG00000169246","Gene description":"Nuclear pore complex interacting protein family member B3","Uniprot":["Q92617"],"Chromosome":"16","Position":"21402237-21448567","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1.6","Excitatory neurons":"1.7","Gastric mucus-secreting cells":"1.2","Inhibitory neurons":"1.2","Microglial cells":"1.8","Oligodendrocyte precursor cells":"1.4","Oligodendrocytes":"1.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-4"}},{"Gene":"NPIPB4","Gene synonym":[],"Ensembl":"ENSG00000185864","Gene description":"Nuclear pore complex interacting protein family member B4","Uniprot":["C9JG80"],"Chromosome":"16","Position":"21834569-21880827","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"144.9","Excitatory neurons":"251.6","Inhibitory neurons":"178.3","Late spermatids":"90.2","Microglial cells":"381.3","Oligodendrocyte precursor cells":"198.8","Oligodendrocytes":"205.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"}},{"Gene":"NPIPB5","Gene synonym":[],"Ensembl":"ENSG00000243716","Gene description":"Nuclear pore complex interacting protein family member B5","Uniprot":["A8MRT5"],"Chromosome":"16","Position":"22479121-22536521","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"51.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-5"}},{"Gene":"NPIPB6","Gene synonym":[],"Ensembl":"ENSG00000198156","Gene description":"Nuclear pore complex interacting protein family member B6","Uniprot":["E9PJ23"],"Chromosome":"16","Position":"28342555-28363508","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"39.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Early spermatids":"197.0","Late spermatids":"206.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"5.7"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011188","HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA011188":"AB_2668455","HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"}},{"Gene":"NPIPB7","Gene synonym":["LOC440350","NPIPL1"],"Ensembl":"ENSG00000233232","Gene description":"Nuclear pore complex interacting protein family member B7","Uniprot":["O75200"],"Chromosome":"16","Position":"28456372-28471175","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"22.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"24","RNA single cell type specific nTPM":{"Early spermatids":"32.1","Late spermatids":"64.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011188","HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA011188":"AB_2668455","HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"}},{"Gene":"NPIPB8","Gene synonym":[],"Ensembl":"ENSG00000255524","Gene description":"Nuclear pore complex interacting protein family member B8","Uniprot":["E9PQR5"],"Chromosome":"16","Position":"28637654-28658682","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"testis":"13.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Early spermatids":"11.8","Late spermatids":"34.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011188","HPA053611"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA011188":"AB_2668455","HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NPIPB9","Gene synonym":[],"Ensembl":"ENSG00000196993","Gene description":"Nuclear pore complex interacting protein family member B9","Uniprot":["F8W1W9"],"Chromosome":"16","Position":"28751787-28772807","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"14.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011188","HPA053611"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 34: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA011188":"AB_2668455","HPA053611":"AB_2682206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-4"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"}},{"Gene":"NPNT","Gene synonym":["EGFL6L","POEM"],"Ensembl":"ENSG00000168743","Gene description":"Nephronectin","Uniprot":["Q6UXI9"],"Chromosome":"4","Position":"105894775-106004027","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"137.0","thyroid gland":"234.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"168.0","Alveolar cells type 2":"89.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"104.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"69.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Kidney - Podocytes","Liver - Hepatic stellate cells","Prostate - Smooth muscle cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003711","HPA050203"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions","Cytosol"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Nucleoplasm","Cell Junctions","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA003711":"AB_1854591","HPA050203":"AB_2681050"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.28e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"}},{"Gene":"NPR1","Gene synonym":["ANPa","ANPRA","GUCY2A","NPRA"],"Ensembl":"ENSG00000169418","Gene description":"Natriuretic peptide receptor 1","Uniprot":["P16066"],"Chromosome":"1","Position":"153678688-153693992","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["cGMP biosynthesis"],"Molecular function":["Lyase","Receptor","Vasoactive"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"67.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"92.4","Alveolar cells type 2":"24.5","Endothelial cells":"55.0","Fibroblasts":"35.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"ovarian cancer":"39.2","renal cancer":"12.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"9.2","ovarian cancer":"8.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"olfactory bulb":"18.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031087"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA031087":"AB_10601975"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.97e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.49e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"}},{"Gene":"NPR2","Gene synonym":["AMDM","ANPb","ANPRB","GUCY2B","NPRB"],"Ensembl":"ENSG00000159899","Gene description":"Natriuretic peptide receptor 2","Uniprot":["P20594"],"Chromosome":"9","Position":"35791591-35809732","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["cGMP biosynthesis","Osteogenesis"],"Molecular function":["Lyase","Receptor"],"Disease involvement":["Disease variant","Dwarfism","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"34.5","Excitatory neurons":"68.2","Inhibitory neurons":"67.3","Microglial cells":"33.7","Oligodendrocyte precursor cells":"49.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Lung - Fibroblast_1","Prostate - Fibroblasts","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"}},{"Gene":"NPR3","Gene synonym":["ANPRC","C5orf23","FLJ14054","GUCY2B","NPRC"],"Ensembl":"ENSG00000113389","Gene description":"Natriuretic peptide receptor 3","Uniprot":["P17342"],"Chromosome":"5","Position":"32689070-32791724","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"107.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"37.4","Cardiomyocytes":"33.7","Distal tubular cells":"37.3","Granulosa cells":"97.1","Proximal tubular cells":"131.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"19.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"3.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"3.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"37.1"},"RNA tissue cell type enrichment":["Pancreas - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052702"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA052702":"AB_2681922"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.43e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"}},{"Gene":"NPSR1","Gene synonym":["GPR154","GPRA","PGR14"],"Ensembl":"ENSG00000187258","Gene description":"Neuropeptide S receptor 1","Uniprot":["Q6W5P4"],"Chromosome":"7","Position":"34658218-34878332","Protein class":["Disease related genes","G-protein coupled receptors","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Asthma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"2.6","Excitatory neurons":"3.7","Inhibitory neurons":"2.1","Late spermatids":"3.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"2.3","pancreatic cancer":"2.0","stomach cancer":"2.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Bile duct cancer":"5.3","colorectal cancer":"5.6","Gastric cancer":"8.7","pancreatic cancer":"2.4"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"6.2"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"}},{"Gene":"NPTN","Gene synonym":["GP55","GP65","np55","np65","SDFR1","SDR1"],"Ensembl":"ENSG00000156642","Gene description":"Neuroplastin","Uniprot":["Q9Y639"],"Chromosome":"15","Position":"73560014-73634134","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Neurogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"213.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Colon - Smooth muscle cells","Kidney - Fibroblasts","Prostate - Smooth muscle cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051497","HPA072453"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA051497":"AB_2681507","HPA072453":"AB_2686523"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"}},{"Gene":"NPY1R","Gene synonym":["NPYR"],"Ensembl":"ENSG00000164128","Gene description":"Neuropeptide Y receptor Y1","Uniprot":["P25929"],"Chromosome":"4","Position":"163323962-163344832","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"119.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"39.2","Fibroblasts":"25.0","Inhibitory neurons":"18.3","Paneth cells":"21.8","Smooth muscle cells":"33.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"breast cancer":"65.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Bone cancer":"61.4","breast cancer":"33.4"},"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Skeletal muscle - Smooth muscle cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.68e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"}},{"Gene":"NPY2R","Gene synonym":[],"Ensembl":"ENSG00000185149","Gene description":"Neuropeptide Y receptor Y2","Uniprot":["P49146"],"Chromosome":"4","Position":"155208636-155217078","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"5.3","breast":"1.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"6.6","Leydig cells":"21.7","Oligodendrocytes":"12.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Neuroblastoma":"4.1"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"amygdala":"12.9","basal ganglia":"12.3","hippocampal formation":"46.7","hypothalamus":"23.7"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"hippocampal formation":"14.2"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NPY4R","Gene synonym":["PP1","PPYR1","Y4"],"Ensembl":"ENSG00000204174","Gene description":"Neuropeptide Y receptor Y4","Uniprot":["P50391"],"Chromosome":"10","Position":"46461099-46465958","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.3","intestine":"6.0","skin 1":"3.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"0.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"2.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bile duct cancer":"10.2"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027863"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027863":"AB_10602819"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"}},{"Gene":"NPY4R2","Gene synonym":["CH17-360D5.1"],"Ensembl":"ENSG00000264717","Gene description":"Neuropeptide Y receptor Y4-2","Uniprot":["P0DQD5"],"Chromosome":"10","Position":"47918739-47923524","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"1.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"2.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027863"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027863":"AB_10602819"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"}},{"Gene":"NPY5R","Gene synonym":["NPYR5"],"Ensembl":"ENSG00000164129","Gene description":"Neuropeptide Y receptor Y5","Uniprot":["Q15761"],"Chromosome":"4","Position":"163343892-163351934","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"7.2","lymphoid tissue":"8.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1.4","Excitatory neurons":"4.6","Inhibitory neurons":"3.4","Smooth muscle cells":"2.6","Spermatocytes":"2.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bone cancer":"7.4"},"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Liver - Hepatic stellate cells","Skin - Eccrine sweat gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-6"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"}},{"Gene":"NRCAM","Gene synonym":["Bravo","KIAA0343"],"Ensembl":"ENSG00000091129","Gene description":"Neuronal cell adhesion molecule","Uniprot":["Q92823"],"Chromosome":"7","Position":"108147623-108456717","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"37.3","brain":"38.3","epididymis":"34.4","retina":"38.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Astrocytes":"593.4","Excitatory neurons":"753.2","Inhibitory neurons":"383.1","Oligodendrocyte precursor cells":"1205.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"57.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"naive CD8 T-cell":"2.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"T-cells":"2.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012606"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"HPA012606":"AB_1854636"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"}},{"Gene":"NRDE2","Gene synonym":["C14orf102","FLJ14051"],"Ensembl":"ENSG00000119720","Gene description":"NRDE-2, necessary for RNA interference, domain containing","Uniprot":["Q9H7Z3"],"Chromosome":"14","Position":"90267860-90331969","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","DNA damage","Mitosis","mRNA processing","mRNA splicing"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"7.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"107.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047050","HPA050583"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA047050":"AB_2679917","HPA050583":"AB_2681182"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"}},{"Gene":"NRG1","Gene synonym":["GGF","HGL","HRG","NDF","NRG1-IT2"],"Ensembl":"ENSG00000157168","Gene description":"Neuregulin 1","Uniprot":["Q02297"],"Chromosome":"8","Position":"31639222-32855666","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Excitatory neurons":"1447.3","Inhibitory neurons":"398.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"55.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"55.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010964"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA010964":"AB_1854641"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"}},{"Gene":"NRG2","Gene synonym":["Don-1","HRG2","NTAK"],"Ensembl":"ENSG00000158458","Gene description":"Neuregulin 2","Uniprot":["O14511"],"Chromosome":"5","Position":"139846779-140043299","Protein class":["Cancer-related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"69.3","Excitatory neurons":"88.6","Inhibitory neurons":"133.5","Oligodendrocyte precursor cells":"136.2","Oligodendrocytes":"48.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038935","HPA047973"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":"Secreted in other tissues","CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA038935":"AB_10672833","HPA047973":"AB_2680226"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"}},{"Gene":"NRG3","Gene synonym":[],"Ensembl":"ENSG00000185737","Gene description":"Neuregulin 3","Uniprot":["P56975"],"Chromosome":"10","Position":"81875194-82987179","Protein class":["Cancer-related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.3","retina":"5.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Astrocytes":"2830.7","Excitatory neurons":"3706.9","Inhibitory neurons":"3014.2","Oligodendrocyte precursor cells":"1125.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"2.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"1.7","skin cancer":"2.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Liver - Vascular Endothelial cells","Skin - Eccrine sweat gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075789"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA075789":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-4"}},{"Gene":"NRG4","Gene synonym":["HRG4"],"Ensembl":"ENSG00000169752","Gene description":"Neuregulin 4","Uniprot":["Q8WWG1"],"Chromosome":"15","Position":"75935969-76059795","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.8","retina":"4.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"17.9","Exocrine glandular cells":"18.1","Gastric mucus-secreting cells":"31.6","Prostatic glandular cells":"15.9","Rod photoreceptor cells":"29.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"3.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"3.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Respiratory ciliated cells","Skeletal muscle - Skeletal myocytes","Stomach - Gastric mucous cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010957"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 20: Airway & Pancreas - Proteolysis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010957":"AB_1079504"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"}},{"Gene":"NRK","Gene synonym":["DKFZp686A17109"],"Ensembl":"ENSG00000123572","Gene description":"Nik related kinase","Uniprot":["Q7Z2Y5"],"Chromosome":"X","Position":"105822539-105958610","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"16.1","ovary":"32.5","placenta":"24.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cytotrophoblasts":"80.0","Leydig cells":"117.7","Syncytiotrophoblasts":"64.5","Theca cells":"60.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"testis cancer":"6.1"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"11","RNA brain regional specific nTPM":{"cerebellum":"7.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"testis cancer":"40.5"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Kidney - Ascending Loop of Henle cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"28","RNA mouse brain regional specific nTPM":{"cerebellum":"14.2"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"41.6"},"Antibody":["HPA017238"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017238":"AB_1854645"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-3"}},{"Gene":"NRM","Gene synonym":["NRM29"],"Ensembl":"ENSG00000137404","Gene description":"Nurim","Uniprot":["Q8IXM6"],"Chromosome":"6","Position":"30688047-30691420","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"30.1","Late spermatids":"60.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072545","HPA073982"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA072545":"AB_2686532","HPA073982":"AB_2686649"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.52e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"}},{"Gene":"NRN1","Gene synonym":["NRN"],"Ensembl":"ENSG00000124785","Gene description":"Neuritin 1","Uniprot":["Q9NPD7"],"Chromosome":"6","Position":"5997999-6007605","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"98.9","parathyroid gland":"81.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Adipocytes":"273.8","Endothelial cells":"119.1","Excitatory neurons":"71.0","Extravillous trophoblasts":"78.5","Schwann cells":"142.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"38.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"MAIT T-cell":"2.6","neutrophil":"2.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"2.2","T-cells":"2.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"96.5"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.79e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-3"}},{"Gene":"NRN1L","Gene synonym":["MRCC2446","UNQ2446"],"Ensembl":"ENSG00000188038","Gene description":"Neuritin 1 like","Uniprot":["Q496H8"],"Chromosome":"16","Position":"67884885-67888855","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"2.8","Oligodendrocytes":"1.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"6.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041761"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041761":"AB_10961155"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-1"}},{"Gene":"NRP1","Gene synonym":["CD304","NRP","VEGF165R"],"Ensembl":"ENSG00000099250","Gene description":"Neuropilin 1","Uniprot":["O14786"],"Chromosome":"10","Position":"33177492-33336262","Protein class":["Cancer-related genes","CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Angiogenesis","Differentiation","Host-virus interaction","Neurogenesis"],"Molecular function":["Developmental protein","Heparin-binding","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"341.0","Endothelial cells":"171.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"48.6"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"plasmacytoid DC":"39.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"dendritic cells":"39.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Prostate - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004511","HPA030278"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"780000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004511":"AB_2282634","HPA030278":"AB_10601976"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.10e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.79e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.22e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"}},{"Gene":"NRP2","Gene synonym":["VEGF165R2"],"Ensembl":"ENSG00000118257","Gene description":"Neuropilin 2","Uniprot":["O60462"],"Chromosome":"2","Position":"205681990-205798133","Protein class":["Cancer-related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Differentiation","Host-virus interaction","Neurogenesis"],"Molecular function":["Developmental protein","Heparin-binding","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"78.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"86.3","Cytotrophoblasts":"92.4","Endothelial cells":"125.1","Hofbauer cells":"123.1","Langerhans cells":"180.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"114.7"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Smooth muscle cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039980","HPA054974"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA039980":"AB_10795517","HPA054974":"AB_2682657"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.68e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.80e-5"}},{"Gene":"NRROS","Gene synonym":["ELLP3030","GARPL1","LRRC33","MGC50789","UNQ3030"],"Ensembl":"ENSG00000174004","Gene description":"Negative regulator of reactive oxygen species","Uniprot":["Q86YC3"],"Chromosome":"3","Position":"196639694-196662004","Protein class":["Disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Growth factor binding"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"32.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"37.5","dendritic cells":"43.2","Erythroid cells":"27.4","Hofbauer cells":"73.2","Kupffer cells":"36.6","Langerhans cells":"77.7","Macrophages":"30.0","Microglial cells":"31.0","monocytes":"40.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"4.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"1.3","granulocytes":"4.2","monocytes":"1.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"72.7","Myeloma":"36.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031586"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031586":"AB_10601543"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.63e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"}},{"Gene":"NRSN1","Gene synonym":["p24","VMP"],"Ensembl":"ENSG00000152954","Gene description":"Neurensin 1","Uniprot":["Q8IZ57"],"Chromosome":"6","Position":"24126186-24154900","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"brain":"542.9","choroid plexus":"474.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"25.4","Excitatory neurons":"137.1","Horizontal cells":"50.0","Inhibitory neurons":"109.3","Oligodendrocyte precursor cells":"66.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"glioma":"3.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Neuroblastoma":"35.8"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019681","HPA061006"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019681":null,"HPA061006":"AB_2684413"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"NRSN2","Gene synonym":["C20orf98","dJ1103G7.6"],"Ensembl":"ENSG00000125841","Gene description":"Neurensin 2","Uniprot":["Q9GZP1"],"Chromosome":"20","Position":"346782-359660","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"154.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015967"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA015967":"AB_1854647"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.61e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"}},{"Gene":"NRXN1","Gene synonym":["Hs.22998","KIAA0578"],"Ensembl":"ENSG00000179915","Gene description":"Neurexin 1","Uniprot":["P58400","Q9ULB1"],"Chromosome":"2","Position":"49918503-51225575","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis","Cell adhesion"],"Molecular function":null,"Disease involvement":["Intellectual disability","Schizophrenia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"145.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"3899.8","Excitatory neurons":"3156.4","Inhibitory neurons":"2058.1","Oligodendrocyte precursor cells":"4690.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"3.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"1.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"4.1","Neuroblastoma":"4.1","thyroid cancer":"4.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Colon - Enteric glia cells","Pancreas - Alpha cells","Testis - Early spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071400"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA071400":"AB_2732180"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"}},{"Gene":"NRXN2","Gene synonym":[],"Ensembl":"ENSG00000110076","Gene description":"Neurexin 2","Uniprot":["P58401","Q9P2S2"],"Chromosome":"11","Position":"64606174-64723197","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"73.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"48.2","Horizontal cells":"157.7","Inhibitory neurons":"46.6","Late spermatids":"47.1","Leydig cells":"43.3","Muller glia cells":"48.5","Oligodendrocyte precursor cells":"45.2","Peritubular cells":"57.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"12.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"21.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Heart muscle - Fibroblasts","Lung - Fibroblast_2","Skeletal muscle - Fibroblasts","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-3"}},{"Gene":"NRXN3","Gene synonym":["C14orf60","KIAA0743"],"Ensembl":"ENSG00000021645","Gene description":"Neurexin 3","Uniprot":["Q9HDB5","Q9Y4C0"],"Chromosome":"14","Position":"78170373-79868291","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"106.8","retina":"42.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Excitatory neurons":"3479.1","Inhibitory neurons":"4960.5","Oligodendrocytes":"2024.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"106.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Smooth muscle cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002727"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"710000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002727":"AB_1079468"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.83e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"}},{"Gene":"NSG1","Gene synonym":["D4S234E","NEEP21","P21"],"Ensembl":"ENSG00000168824","Gene description":"Neuronal vesicle trafficking associated 1","Uniprot":["P42857"],"Chromosome":"4","Position":"4348140-4419058","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"95.7","pituitary gland":"135.1","skin 1":"120.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"192.6","Cytotrophoblasts":"120.3","Granulosa cells":"124.0","Melanocytes":"426.7","Suprabasal keratinocytes":"146.3","Theca cells":"129.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"melanoma":"61.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"gdT-cell":"45.2","MAIT T-cell":"61.9","memory CD4 T-cell":"42.2","memory CD8 T-cell":"37.1","naive CD8 T-cell":"27.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"57","RNA blood lineage specific nTPM":{"T-cells":"61.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"61.4","skin cancer":"66.8"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast myoepithelial cells","Colon - Colon enteroendocrine cells","Kidney - Proximal tubular cells","Pancreas - Alpha cells","Pancreas - Beta cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.49e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"}},{"Gene":"NSG2","Gene synonym":["CALY3","HMP19"],"Ensembl":"ENSG00000170091","Gene description":"Neuronal vesicle trafficking associated 2","Uniprot":["Q9Y328"],"Chromosome":"5","Position":"174045706-174243501","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"198.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"30.6","Excitatory neurons":"44.7","Horizontal cells":"92.3","Inhibitory neurons":"95.6","Oligodendrocyte precursor cells":"94.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"12.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"165.1","thyroid cancer":"76.7"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046531","HPA056191"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA046531":"AB_2732528","HPA056191":"AB_2683062"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"}},{"Gene":"NSMCE3","Gene synonym":["HCA4","MAGEG1","MAGEL3","NDNL2","NSE3"],"Ensembl":"ENSG00000185115","Gene description":"NSE3 homolog, SMC5-SMC6 complex component","Uniprot":["Q96MG7"],"Chromosome":"15","Position":"29264989-29269822","Protein class":["Disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA recombination","DNA repair","Growth regulation","Ubl conjugation pathway"],"Molecular function":["Tumor antigen"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"T-cells":"99.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"}},{"Gene":"NSMF","Gene synonym":["NELF"],"Ensembl":"ENSG00000165802","Gene description":"NMDA receptor synaptonuclear signaling and neuronal migration factor","Uniprot":["Q6X4W1"],"Chromosome":"9","Position":"137447570-137459334","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism","Kallmann syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"361.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"69.3","Peritubular cells":"73.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"3.5","intermediate monocyte":"13.8","myeloid DC":"6.3","non-classical monocyte":"12.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"6.3","granulocytes":"3.5","monocytes":"13.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044316"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA044316":"AB_10964877"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"}},{"Gene":"NT5E","Gene synonym":["CALJA","CD73","eN","eNT","NT5"],"Ensembl":"ENSG00000135318","Gene description":"5'-nucleotidase ecto","Uniprot":["P21589"],"Chromosome":"6","Position":"85449584-85495791","Protein class":["CD markers","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"112.6","retina":"94.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"63.2","Oligodendrocyte precursor cells":"58.7","Paneth cells":"57.7","Rod photoreceptor cells":"79.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"33.0","naive CD8 T-cell":"30.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"41","RNA blood lineage specific nTPM":{"B-cells":"33.0","T-cells":"30.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Heart muscle - Fibroblasts","Lung - Fibroblast_2","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017357"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3000000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA017357":"AB_1846330"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.66e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"}},{"Gene":"NTF3","Gene synonym":["NGF2"],"Ensembl":"ENSG00000185652","Gene description":"Neurotrophin 3","Uniprot":["P20783"],"Chromosome":"12","Position":"5432108-5521536","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"12.7","Basal squamous epithelial cells":"48.6","Breast myoepithelial cells":"11.7","Peritubular cells":"11.0","Sertoli cells":"13.8","Smooth muscle cells":"18.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"2.2"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"3.4","cerebral cortex":"1.3","hippocampal formation":"1.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Kidney - Fibroblasts","Lung - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"cerebellum":"4.7","cerebral cortex":"2.0","hippocampal formation":"2.2"},"Antibody":["HPA032001"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA032001":"AB_2674106"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-3"}},{"Gene":"NTM","Gene synonym":["CEPU-1","HNT","IGLON2","NTRI"],"Ensembl":"ENSG00000182667","Gene description":"Neurotrimin","Uniprot":["Q9P121"],"Chromosome":"11","Position":"131370478-132336822","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"321.8","choroid plexus":"89.2","retina":"74.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"2096.8","Cone photoreceptor cells":"486.0","Excitatory neurons":"641.6","Inhibitory neurons":"1032.5","Oligodendrocyte precursor cells":"1848.9","Oligodendrocytes":"1187.2","Rod photoreceptor cells":"1314.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"175","RNA blood cell specific nTPM":{"plasmacytoid DC":"17.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"175","RNA blood lineage specific nTPM":{"dendritic cells":"17.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bone cancer":"26.0","Brain cancer":"19.5","Kidney cancer":"9.4","Sarcoma":"17.3","skin cancer":"21.2","thyroid cancer":"21.1"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Skeletal muscle - Fibroblasts","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB024875"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB024875":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.10e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-3"}},{"Gene":"NTMT1","Gene synonym":["AD-003","C9orf32","HOMT1A","METTL11A","NRMT","NRMT1"],"Ensembl":"ENSG00000148335","Gene description":"N-terminal Xaa-Pro-Lys N-methyltransferase 1","Uniprot":["Q9BV86"],"Chromosome":"9","Position":"129608884-129636135","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"301.6","Late spermatids":"790.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020092","HPA058420"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA020092":"AB_1853831","HPA058420":"AB_2683713"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-3"}},{"Gene":"NTNG1","Gene synonym":["KIAA0976","Lmnt1"],"Ensembl":"ENSG00000162631","Gene description":"Netrin G1","Uniprot":["Q9Y2I2"],"Chromosome":"1","Position":"107140007-107484923","Protein class":["Predicted intracellular proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"75.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"120.6","Inhibitory neurons":"158.5","Oligodendrocyte precursor cells":"407.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"75.1"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"11.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Podocytes","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"hippocampal formation":"19.7","midbrain":"61.3","pons":"56.0","thalamus":"76.4"},"Antibody":["HPA065954"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA065954":"AB_2685585"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-5"}},{"Gene":"NTRK1","Gene synonym":["MTC","TRK","TRKA"],"Ensembl":"ENSG00000198400","Gene description":"Neurotrophic receptor tyrosine kinase 1","Uniprot":["P04629"],"Chromosome":"1","Position":"156815640-156881850","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"7.0","brain":"21.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"25.4","granulocytes":"30.0","Horizontal cells":"18.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.3"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"7.6","medulla oblongata":"19.8","pons":"21.7"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"116","RNA blood cell specific nTPM":{"basophil":"94.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"768","RNA blood lineage specific nTPM":{"granulocytes":"94.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"8.5","Neuroblastoma":"17.7"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Kidney - Intercalated cells","Lung - Mast cells","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"8.4"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"4.1"},"Antibody":["CAB004606","HPA035799","HPA076570","CAB080140"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"79000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004606":"AB_628397","CAB080140":null,"HPA035799":"AB_2674788","HPA076570":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-1"}},{"Gene":"NTRK2","Gene synonym":["TRKB"],"Ensembl":"ENSG00000148053","Gene description":"Neurotrophic receptor tyrosine kinase 2","Uniprot":["Q16620"],"Chromosome":"9","Position":"84668551-85027054","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","FDA approved drug targets","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"230.0","thyroid gland":"116.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1108.7","Excitatory neurons":"739.7","Inhibitory neurons":"857.4","Oligodendrocyte precursor cells":"534.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"31.6","head and neck cancer":"8.0","lung cancer":"9.8","thyroid cancer":"26.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"7.4","Esophageal cancer":"8.8"},"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007637","CAB010346","HPA074873"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010346":"AB_2155274","HPA007637":"AB_1080385","HPA074873":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"}},{"Gene":"NTRK3","Gene synonym":["TRKC"],"Ensembl":"ENSG00000140538","Gene description":"Neurotrophic receptor tyrosine kinase 3","Uniprot":["Q16288"],"Chromosome":"15","Position":"87859751-88256768","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"38.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"231.9","Early spermatids":"115.0","Excitatory neurons":"355.3","Inhibitory neurons":"271.7","Late spermatids":"154.8","Microglial cells":"172.4","Oligodendrocyte precursor cells":"478.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"2.5","testis cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"7.8","Neuroblastoma":"8.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Heart muscle - Smooth muscle cells","Skeletal muscle - Smooth muscle cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009233","HPA027484","HPA048065"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Nucleoli","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"CAB009233":"AB_632555","HPA027484":"AB_2672297","HPA048065":"AB_2680245"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"}},{"Gene":"NTSR1","Gene synonym":["NTR"],"Ensembl":"ENSG00000101188","Gene description":"Neurotensin receptor 1","Uniprot":["P30989"],"Chromosome":"20","Position":"62708836-62762771","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"brain":"11.2","intestine":"11.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"3.3","Excitatory neurons":"1.5","Inhibitory neurons":"1.3","Kupffer cells":"5.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"2.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"midbrain":"11.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"14.1"},"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Lung - Neutrophil_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050299"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA050299":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"}},{"Gene":"NTSR2","Gene synonym":["NTR2"],"Ensembl":"ENSG00000169006","Gene description":"Neurotensin receptor 2","Uniprot":["O95665"],"Chromosome":"2","Position":"11658178-11670195","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"58","RNA tissue specific nTPM":{"brain":"85.4","choroid plexus":"43.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Astrocytes":"31.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"glioma":"6.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NUAK1","Gene synonym":["ARK5","KIAA0537"],"Ensembl":"ENSG00000074590","Gene description":"NUAK family kinase 1","Uniprot":["O60285"],"Chromosome":"12","Position":"106063345-106138954","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion","DNA damage"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"66.8","Cardiomyocytes":"63.7","Endothelial cells":"138.7","Excitatory neurons":"148.4","Microglial cells":"91.2","Oligodendrocytes":"69.4","Salivary duct cells":"60.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Stomach - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057143"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Microtubules"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Nucleoplasm","Microtubules"],"Antibody RRID":{"HPA057143":"AB_2683349"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.83e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.27e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"}},{"Gene":"NUAK2","Gene synonym":["FLJ90349","SNARK"],"Ensembl":"ENSG00000163545","Gene description":"NUAK family kinase 2","Uniprot":["Q9H093"],"Chromosome":"1","Position":"205302063-205321745","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"56.7","vagina":"45.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"47.2","Endometrial ciliated cells":"44.4","Glandular and luminal cells":"51.7","Intestinal goblet cells":"45.8","Suprabasal keratinocytes":"80.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"120.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"45.6"},"RNA tissue cell type enrichment":["Pancreas - Ductal cells","Skin - Keratinocyte (other)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008958"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008958":"AB_1080040"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.01e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.94e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"}},{"Gene":"NUDT14","Gene synonym":["UGPP"],"Ensembl":"ENSG00000183828","Gene description":"Nudix hydrolase 14","Uniprot":["O95848"],"Chromosome":"14","Position":"105172938-105181323","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"217.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046755","HPA058759"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Microtubules"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA046755":"AB_10963433","HPA058759":"AB_2683809"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.66e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"}},{"Gene":"NUDT22","Gene synonym":["MGC13045"],"Ensembl":"ENSG00000149761","Gene description":"Nudix hydrolase 22","Uniprot":["Q9BRQ3"],"Chromosome":"11","Position":"64225941-64230686","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039334","HPA053464"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA039334":"AB_10795174","HPA053464":"AB_2682160"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.18e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"}},{"Gene":"NUDT7","Gene synonym":[],"Ensembl":"ENSG00000140876","Gene description":"Nudix hydrolase 7","Uniprot":["P0C024"],"Chromosome":"16","Position":"77722492-77742260","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"70.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"49.8","Hepatocytes":"48.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042042"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA042042":"AB_10806232"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.84e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.36e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"}},{"Gene":"NUP107","Gene synonym":["NUP84"],"Ensembl":"ENSG00000111581","Gene description":"Nucleoporin 107","Uniprot":["P57740"],"Chromosome":"12","Position":"68686951-68745809","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"90.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031679"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nuclear membrane","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear membrane","Centrosome"],"Antibody RRID":{"HPA031679":"AB_2673992"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.12e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.28e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"}},{"Gene":"NUP188","Gene synonym":["KIAA0169"],"Ensembl":"ENSG00000095319","Gene description":"Nucleoporin 188","Uniprot":["Q5SRE5"],"Chromosome":"9","Position":"128947699-129007096","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Cataract","Disease variant","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"50.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061750","HPA063942"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA061750":"AB_2684602","HPA063942":"AB_2685156"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.20e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"}},{"Gene":"NUP205","Gene synonym":["C7orf14","KIAA0225"],"Ensembl":"ENSG00000155561","Gene description":"Nucleoporin 205","Uniprot":["Q92621"],"Chromosome":"7","Position":"135557917-135648757","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"}},{"Gene":"NUP210","Gene synonym":["FLJ22389","GP210","KIAA0906","POM210"],"Ensembl":"ENSG00000132182","Gene description":"Nucleoporin 210","Uniprot":["Q8TEM1"],"Chromosome":"3","Position":"13316235-13420322","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"53.4","lymphoid tissue":"41.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"68.3","Granulosa cells":"73.0","Horizontal cells":"52.6","NK-cells":"55.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Lung - T-cells","Testis - Spermatocytes","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066888"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"78000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066888":"AB_2685741"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"}},{"Gene":"NUP210L","Gene synonym":[],"Ensembl":"ENSG00000143552","Gene description":"Nucleoporin 210 like","Uniprot":["Q5VU65"],"Chromosome":"1","Position":"153992685-154155116","Protein class":["Cancer-related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"testis":"26.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"23.7","Excitatory neurons":"6.9","Inhibitory neurons":"8.2","Late spermatids":"8.5","Oligodendrocytes":"18.2","Spermatocytes":"23.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047195","HPA064245","HPA066707"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA047195":"AB_2679980","HPA064245":"AB_2685224","HPA066707":"AB_2685706"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"}},{"Gene":"NUP42","Gene synonym":["CG1","H_RG271G13.9","hCG1","NLP_1","NUPL2"],"Ensembl":"ENSG00000136243","Gene description":"Nucleoporin 42","Uniprot":["O15504"],"Chromosome":"7","Position":"23181841-23201011","Protein class":["Metabolic proteins","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"294.7","Oligodendrocyte precursor cells":"115.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049036","HPA057251"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA049036":null,"HPA057251":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"}},{"Gene":"NUP85","Gene synonym":["FLJ12549","NUP75"],"Ensembl":"ENSG00000125450","Gene description":"Nucleoporin 85","Uniprot":["Q9BW27"],"Chromosome":"17","Position":"75205659-75235758","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061910","HPA062595"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA061910":"AB_2684634","HPA062595":"AB_2684801"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.32e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"}},{"Gene":"NUP88","Gene synonym":["MGC8530"],"Ensembl":"ENSG00000108559","Gene description":"Nucleoporin 88","Uniprot":["Q99567"],"Chromosome":"17","Position":"5360963-5419676","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"168.5","Spermatocytes":"143.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002209","HPA021816"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB002209":"AB_564128","HPA021816":"AB_1854725"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"}},{"Gene":"NUP93","Gene synonym":["KIAA0095"],"Ensembl":"ENSG00000102900","Gene description":"Nucleoporin 93","Uniprot":["Q8N1F7"],"Chromosome":"16","Position":"56730118-56850286","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017937"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017937":"AB_1854726"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"}},{"Gene":"NUPR1","Gene synonym":["COM1","p8"],"Ensembl":"ENSG00000176046","Gene description":"Nuclear protein 1, transcriptional regulator","Uniprot":["O60356"],"Chromosome":"16","Position":"28532708-28539008","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"1157.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"223.1","Fibroblasts":"87.4","Squamous epithelial cells":"187.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"14.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"granulocytes":"14.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006349"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA006349":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"}},{"Gene":"NUS1","Gene synonym":["C6orf68","MGC7199","NgBR","TANGO14"],"Ensembl":"ENSG00000153989","Gene description":"NUS1 dehydrodolichyl diphosphate synthase subunit","Uniprot":["Q96E22"],"Chromosome":"6","Position":"117675469-117710727","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Angiogenesis","Differentiation","Lipid metabolism"],"Molecular function":["Developmental protein","Receptor","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027504"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA027504":"AB_10603124"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"}},{"Gene":"NVL","Gene synonym":["NVL2"],"Ensembl":"ENSG00000143748","Gene description":"Nuclear VCP like","Uniprot":["O15381"],"Chromosome":"1","Position":"224227334-224330189","Protein class":["Predicted intracellular proteins"],"Biological process":["Ribosome biogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028207","HPA028219","HPA028224","HPA028654"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA028207":"AB_10601382","HPA028219":"AB_2672526","HPA028224":"AB_2672529","HPA028654":"AB_2672714"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.77e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.95e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.10e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"NXPE1","Gene synonym":["FAM55A","MGC34290"],"Ensembl":"ENSG00000095110","Gene description":"Neurexophilin and PC-esterase domain family member 1","Uniprot":["Q8N323"],"Chromosome":"11","Position":"114521645-114559895","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"intestine":"79.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"32.8","Early spermatids":"81.3","Enteroendocrine cells":"19.5","Intestinal goblet cells":"58.4","Late spermatids":"51.1","Paneth cells":"23.0","Undifferentiated cells":"25.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"23","RNA cancer specific FPKM":{"colorectal cancer":"3.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049133"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049133":"AB_2680647"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"NXPE2","Gene synonym":["FAM55B","FLJ25224"],"Ensembl":"ENSG00000204361","Gene description":"Neurexophilin and PC-esterase domain family member 2","Uniprot":["Q96DL1"],"Chromosome":"11","Position":"114678527-114707069","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"epididymis":"25.3","intestine":"9.9","salivary gland":"21.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"2.7","Intestinal goblet cells":"6.8","Mucus glandular cells":"6.4","Serous glandular cells":"15.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"1.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039744","HPA039876"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039744":"AB_2676660","HPA039876":"AB_2676721"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.29e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"NXPH4","Gene synonym":["NPH4"],"Ensembl":"ENSG00000182379","Gene description":"Neurexophilin 4","Uniprot":["O95158"],"Chromosome":"12","Position":"57216794-57226449","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.4","skin 1":"19.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"10.3","Cone photoreceptor cells":"8.6","Cytotrophoblasts":"27.2","Muller glia cells":"17.2","Prostatic glandular cells":"10.5","Syncytiotrophoblasts":"25.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.21e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.42e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.57e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.68e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"}},{"Gene":"OAZ2","Gene synonym":[],"Ensembl":"ENSG00000180304","Gene description":"Ornithine decarboxylase antizyme 2","Uniprot":["O95190"],"Chromosome":"15","Position":"64687573-64703281","Protein class":["Predicted intracellular proteins"],"Biological process":["Polyamine biosynthesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"418.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047694"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA047694":"AB_2680121"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.05e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"}},{"Gene":"OBSCN","Gene synonym":["ARHGEF30","KIAA1556","KIAA1639","UNC89"],"Ensembl":"ENSG00000154358","Gene description":"Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF","Uniprot":["Q5VST9"],"Chromosome":"1","Position":"228208044-228378876","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Differentiation"],"Molecular function":["Calmodulin-binding","Developmental protein","Kinase","Muscle protein","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"skeletal muscle":"481.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Cardiomyocytes":"140.3","Skeletal myocytes":"420.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Cardiomyocytes","Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021186","HPA065801"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4500000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA021186":"AB_1854761","HPA065801":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.64e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"}},{"Gene":"OCA2","Gene synonym":["BEY","BEY1","BEY2","D15S12","EYCL","EYCL2","EYCL3","P"],"Ensembl":"ENSG00000104044","Gene description":"OCA2 melanosomal transmembrane protein","Uniprot":["Q04671"],"Chromosome":"15","Position":"27754875-28099315","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Albinism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"choroid plexus":"28.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"30.4","Inhibitory neurons":"39.8","Melanocytes":"66.2","Peritubular cells":"15.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"melanoma":"19.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"skin cancer":"23.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Skin - Melanocytes","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036402"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA036402":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"}},{"Gene":"OCEL1","Gene synonym":["FLJ22709"],"Ensembl":"ENSG00000099330","Gene description":"Occludin\/ELL domain containing 1","Uniprot":["Q9H607"],"Chromosome":"19","Position":"17226213-17229219","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"75.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"110.1","Proximal enterocytes":"131.3","Proximal tubular cells":"135.2","Syncytiotrophoblasts":"121.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042070","HPA043223"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA042070":"AB_2677830","HPA043223":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"}},{"Gene":"OCLN","Gene synonym":["PPP1R115"],"Ensembl":"ENSG00000197822","Gene description":"Occludin","Uniprot":["Q16625"],"Chromosome":"5","Position":"69492292-69558104","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"31.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"104.5","Endometrial ciliated cells":"91.2","Glandular and luminal cells":"121.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"2.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005933","CAB013075","CAB068212","CAB068213","CAB068214"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB013075":"AB_2533101","CAB068212":"AB_2665711","CAB068213":"AB_2665712","CAB068214":"AB_2665713","HPA005933":"AB_1079520"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.59e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"}},{"Gene":"OCSTAMP","Gene synonym":["C20orf123","dJ257E24.3"],"Ensembl":"ENSG00000149635","Gene description":"Osteoclast stimulatory transmembrane protein","Uniprot":["Q9BR26"],"Chromosome":"20","Position":"46540946-46550654","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.0","Myeloma":"4.2"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031116"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031116":"AB_10600758"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"ODF4","Gene synonym":["CT136","OPPO1"],"Ensembl":"ENSG00000184650","Gene description":"Outer dense fiber of sperm tails 4","Uniprot":["Q2M2E3"],"Chromosome":"17","Position":"8339840-8346048","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"131","RNA tissue specific nTPM":{"testis":"13.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Early spermatids":"41.3","Late spermatids":"32.3","Spermatocytes":"39.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072129"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA072129":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"}},{"Gene":"ODR4","Gene synonym":["C1orf27","FLJ20505","odr-4","TTG1"],"Ensembl":"ENSG00000157181","Gene description":"Odr-4 GPCR localization factor homolog","Uniprot":["Q5SWX8"],"Chromosome":"1","Position":"186375838-186421378","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015988","HPA031352"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA015988":"AB_1845644","HPA031352":"AB_2673838"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.92e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"}},{"Gene":"OGDH","Gene synonym":["E1k","KGD1","OGDC-E1","OGDH2"],"Ensembl":"ENSG00000105953","Gene description":"Oxoglutarate dehydrogenase","Uniprot":["Q02218"],"Chromosome":"7","Position":"44606572-44709066","Protein class":["Citric acid cycle related proteins","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"324.0","skeletal muscle":"363.6","tongue":"374.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019514","HPA020347"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA019514":"AB_1854772","HPA020347":"AB_1854773"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.22e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-3"}},{"Gene":"OGFOD3","Gene synonym":["C17orf101","FLJ22222"],"Ensembl":"ENSG00000181396","Gene description":"2-oxoglutarate and iron dependent oxygenase domain containing 3","Uniprot":["Q6PK18"],"Chromosome":"17","Position":"82389210-82418637","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052099"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9700","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA052099":"AB_2681725"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.72e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"OGN","Gene synonym":["mimecan","OIF","SLRR3A"],"Ensembl":"ENSG00000106809","Gene description":"Osteoglycin","Uniprot":["P20774"],"Chromosome":"9","Position":"92383268-92404696","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"216.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"108.9","Fibroblasts":"181.8","Leydig cells":"166.5","Peritubular cells":"203.7","Thymic epithelial cells":"677.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"T-reg":"1.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"1.7"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"21.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Fibroblasts","Heart muscle - Fibroblasts","Liver - Hepatic stellate cells","Lung - Fibroblast_2","Pancreas - Fibroblasts","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Fibroblast_1","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013132"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA013132":"AB_1854825"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.04e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.03e-4"}},{"Gene":"OLA1","Gene synonym":["GTPBP9","PTD004"],"Ensembl":"ENSG00000138430","Gene description":"Obg like ATPase 1","Uniprot":["Q9NTK5"],"Chromosome":"2","Position":"174072447-174248599","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035790","HPA041443"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035790":"AB_10601977","HPA041443":"AB_2677483"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.73e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"}},{"Gene":"OLAH","Gene synonym":["FLJ11106","SAST","THEDC1"],"Ensembl":"ENSG00000152463","Gene description":"Oleoyl-ACP hydrolase","Uniprot":["Q9NV23"],"Chromosome":"10","Position":"15032227-15073853","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"9.0","testis":"27.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"673.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"testis cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"2.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037947","HPA037948"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037947":"AB_10795028","HPA037948":"AB_10805352"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"}},{"Gene":"OLR1","Gene synonym":["CLEC8A","LOX-1","SCARE1"],"Ensembl":"ENSG00000173391","Gene description":"Oxidized low density lipoprotein receptor 1","Uniprot":["P78380"],"Chromosome":"12","Position":"10158301-10172138","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Immunity","Inflammatory response"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"52.6","lung":"100.2","placenta":"114.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cytotrophoblasts":"383.4","Hofbauer cells":"218.7","Langerhans cells":"115.9","Macrophages":"149.0","monocytes":"159.4","Syncytiotrophoblasts":"415.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"2.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"148.7","head and neck cancer":"80.5"},"RNA tissue cell type enrichment":["Prostate - T-cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050798"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1060000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA050798":"AB_2756318"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.24e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"}},{"Gene":"OMA1","Gene synonym":["FLJ33782","MPRP-1","YKR087C","ZMPOMA1"],"Ensembl":"ENSG00000162600","Gene description":"OMA1 zinc metallopeptidase","Uniprot":["Q96E52"],"Chromosome":"1","Position":"58415384-58546802","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"100.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055120"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA055120":"AB_2682702"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.63e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.70e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.52e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"}},{"Gene":"OOSP1","Gene synonym":[],"Ensembl":"ENSG00000284873","Gene description":"Oocyte secreted protein 1","Uniprot":[],"Chromosome":"11","Position":"59938432-59957480","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"2.2","Inhibitory neurons":"1.5"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OPA1","Gene synonym":["FLJ12460","KIAA0567","MGM1","NPG","NTG"],"Ensembl":"ENSG00000198836","Gene description":"OPA1 mitochondrial dynamin like GTPase","Uniprot":["O60313"],"Chromosome":"3","Position":"193593144-193697811","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Apoptosis","Sensory transduction","Vision"],"Molecular function":["Hydrolase"],"Disease involvement":["Cardiomyopathy","Deafness","Disease variant","Neurodegeneration","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"219.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036926","HPA036927"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA036926":"AB_10671247","HPA036927":"AB_2675388"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.44e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.84e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"}},{"Gene":"OPA3","Gene synonym":["FLJ22187","MGA3"],"Ensembl":"ENSG00000125741","Gene description":"Outer mitochondrial membrane lipid metabolism regulator OPA3","Uniprot":["Q9H6K4"],"Chromosome":"19","Position":"45527427-45602212","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Cataract","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044881"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA044881":"AB_10964052"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.60e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.30e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"}},{"Gene":"OPALIN","Gene synonym":["HTMP10","TMEM10","TMP10"],"Ensembl":"ENSG00000197430","Gene description":"Oligodendrocytic myelin paranodal and inner loop protein","Uniprot":["Q96PE5"],"Chromosome":"10","Position":"96343221-96359365","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"654","RNA tissue specific nTPM":{"brain":"166.5","choroid plexus":"47.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"298","RNA single cell type specific nTPM":{"Oligodendrocytes":"287.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"36","RNA cancer specific FPKM":{"glioma":"1.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"white matter":"240.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014372"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014372":"AB_2158172"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OPN1LW","Gene synonym":["CBBM","CBP","COD5","RCP"],"Ensembl":"ENSG00000102076","Gene description":"Opsin 1, long wave sensitive","Uniprot":["P04000"],"Chromosome":"X","Position":"154144243-154159032","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"2568","RNA tissue specific nTPM":{"retina":"256.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"25","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1981.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OPN1MW","Gene synonym":["CBBM","CBD","COD5","GCP","OPN1MW1"],"Ensembl":"ENSG00000268221","Gene description":"Opsin 1, medium wave sensitive","Uniprot":["P04001"],"Chromosome":"X","Position":"154182596-154196861","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"133","RNA tissue specific nTPM":{"retina":"13.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"51","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"110.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OPN1MW2","Gene synonym":[],"Ensembl":"ENSG00000166160","Gene description":"Opsin 1, medium wave sensitive 2","Uniprot":["P0DN77"],"Chromosome":"X","Position":"154219756-154233286","Protein class":["Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"458","RNA tissue specific nTPM":{"retina":"45.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OPN1MW3","Gene synonym":[],"Ensembl":"ENSG00000269433","Gene description":"Opsin 1, medium wave sensitive 3","Uniprot":["P0DN78"],"Chromosome":"X","Position":"154257538-154271805","Protein class":["Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OPN1SW","Gene synonym":["BCP","BOP","CBT"],"Ensembl":"ENSG00000128617","Gene description":"Opsin 1, short wave sensitive","Uniprot":["P03999"],"Chromosome":"7","Position":"128772485-128775794","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"84","RNA tissue specific nTPM":{"retina":"41.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"86.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013562","HPA014083"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA013562":"AB_2668850","HPA014083":"AB_2668938"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.50e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.98e-8"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.33e-4"}},{"Gene":"OPN3","Gene synonym":["ECPN","encephalopsin","ERO","NMO-1","PPP1R116"],"Ensembl":"ENSG00000054277","Gene description":"Opsin 3","Uniprot":["Q9H1Y3"],"Chromosome":"1","Position":"241590102-241677376","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"18.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"213.1","Early spermatids":"148.4","Extravillous trophoblasts":"282.3","Langerhans cells":"254.6","Late spermatids":"108.3","Syncytiotrophoblasts":"157.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"plasmacytoid DC":"10.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"10.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013682","HPA064443"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB013682":null,"HPA064443":"AB_2685267"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.17e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-3"}},{"Gene":"OPN4","Gene synonym":["melanopsin","MOP"],"Ensembl":"ENSG00000122375","Gene description":"Opsin 4","Uniprot":["Q9UHM6"],"Chromosome":"10","Position":"86654547-86666848","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Biological rhythms","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"7.9","skeletal muscle":"2.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"2.8","Horizontal cells":"1.3","Inhibitory neurons":"1.8","Smooth muscle cells":"1.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"7.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039147"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039147":"AB_10673304"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"}},{"Gene":"OPN5","Gene synonym":["dJ402H5.1","neuropsin","TMEM13"],"Ensembl":"ENSG00000124818","Gene description":"Opsin 5","Uniprot":["Q6U736"],"Chromosome":"6","Position":"47781982-47832780","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"2.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"28.8","Late spermatids":"26.1","Spermatocytes":"10.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026084"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026084":"AB_2671807"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OPRD1","Gene synonym":[],"Ensembl":"ENSG00000116329","Gene description":"Opioid receptor delta 1","Uniprot":["P41143"],"Chromosome":"1","Position":"28812142-28871267","Protein class":["FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"4.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"11.6","Inhibitory neurons":"15.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"6.9","skin cancer":"4.4"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Proximal tubular cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070831"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA070831":"AB_2732167"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-3"}},{"Gene":"OPRK1","Gene synonym":["KOR","OPRK"],"Ensembl":"ENSG00000082556","Gene description":"Opioid receptor kappa 1","Uniprot":["P41145"],"Chromosome":"8","Position":"53225724-53251637","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Behavior"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"14.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"6.6","Extravillous trophoblasts":"9.3","Glandular and luminal cells":"8.7","Inhibitory neurons":"9.9","Leydig cells":"5.2","Prostatic glandular cells":"18.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"1.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"2.1","prostate cancer":"4.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067549"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA067549":"AB_2732770"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"}},{"Gene":"OPRL1","Gene synonym":["KOR-3","NOCIR","NOPr","OOR","ORL1"],"Ensembl":"ENSG00000125510","Gene description":"Opioid related nociceptin receptor 1","Uniprot":["P41146"],"Chromosome":"20","Position":"64080082-64100643","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Behavior"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"4.5","testis":"6.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"12.1","Excitatory neurons":"6.2","Late spermatids":"32.1","monocytes":"6.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"classical monocyte":"3.9","eosinophil":"5.8","intermediate monocyte":"5.5","myeloid DC":"4.7","neutrophil":"4.9","non-classical monocyte":"12.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"4.7","granulocytes":"5.8","monocytes":"12.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-3"}},{"Gene":"OPRM1","Gene synonym":["MOR1"],"Ensembl":"ENSG00000112038","Gene description":"Opioid receptor mu 1","Uniprot":["P35372"],"Chromosome":"6","Position":"154010496-154246867","Protein class":["FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"10.6","testis":"2.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"34.1","Excitatory neurons":"40.6","Inhibitory neurons":"22.9","Late spermatids":"35.3","Microglial cells":"10.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Neuroblastoma":"4.2"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014509","HPA067435"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014509":"AB_1854801","HPA067435":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10A2","Gene synonym":["OR10A2P","OST363"],"Ensembl":"ENSG00000170790","Gene description":"Olfactory receptor family 10 subfamily A member 2","Uniprot":["Q9H208"],"Chromosome":"11","Position":"6863057-6874717","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"3.4","Horizontal cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10A3","Gene synonym":["HSHTPCRX12","HTPCRX12"],"Ensembl":"ENSG00000170683","Gene description":"Olfactory receptor family 10 subfamily A member 3","Uniprot":["P58181"],"Chromosome":"11","Position":"7937171-7941708","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"}},{"Gene":"OR10A4","Gene synonym":["OR10A4P"],"Ensembl":"ENSG00000170782","Gene description":"Olfactory receptor family 10 subfamily A member 4","Uniprot":["Q9H209"],"Chromosome":"11","Position":"6876625-6877619","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10A5","Gene synonym":["JCG6","OR10A1","OR11-403"],"Ensembl":"ENSG00000166363","Gene description":"Olfactory receptor family 10 subfamily A member 5","Uniprot":["Q9H207"],"Chromosome":"11","Position":"6845652-6846705","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-5"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10A6","Gene synonym":[],"Ensembl":"ENSG00000279000","Gene description":"Olfactory receptor family 10 subfamily A member 6 (gene\/pseudogene)","Uniprot":["Q8NH74"],"Chromosome":"11","Position":"7924592-7931268","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10A7","Gene synonym":[],"Ensembl":"ENSG00000179919","Gene description":"Olfactory receptor family 10 subfamily A member 7","Uniprot":["Q8NGE5"],"Chromosome":"12","Position":"55221025-55221975","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055111"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055111":"AB_2682698"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10AD1","Gene synonym":["OR10AD1P"],"Ensembl":"ENSG00000172640","Gene description":"Olfactory receptor family 10 subfamily AD member 1","Uniprot":["Q8NGE0"],"Chromosome":"12","Position":"48202083-48203387","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.3","retina":"2.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049913"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049913":"AB_2680950"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10AG1","Gene synonym":[],"Ensembl":"ENSG00000174970","Gene description":"Olfactory receptor family 10 subfamily AG member 1","Uniprot":["Q8NH19"],"Chromosome":"11","Position":"55965755-55969945","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10C1","Gene synonym":["hs6M1-17","OR10C1P","OR10C2"],"Ensembl":"ENSG00000206474","Gene description":"Olfactory receptor family 10 subfamily C member 1","Uniprot":["Q96KK4"],"Chromosome":"6","Position":"29439306-29440977","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049336"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049336":"AB_2680718"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10D3","Gene synonym":["HTPCRX09","OR10D3P"],"Ensembl":"ENSG00000197309","Gene description":"Olfactory receptor family 10 subfamily D member 3","Uniprot":["Q8NH80"],"Chromosome":"11","Position":"124183219-124188780","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10G2","Gene synonym":[],"Ensembl":"ENSG00000255582","Gene description":"Olfactory receptor family 10 subfamily G member 2","Uniprot":["Q8NGC3"],"Chromosome":"14","Position":"21633836-21634940","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-3"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10G3","Gene synonym":[],"Ensembl":"ENSG00000169208","Gene description":"Olfactory receptor family 10 subfamily G member 3","Uniprot":["Q8NGC4"],"Chromosome":"14","Position":"21568520-21580076","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019766"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019766":"AB_1854780"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10G4","Gene synonym":[],"Ensembl":"ENSG00000254737","Gene description":"Olfactory receptor family 10 subfamily G member 4","Uniprot":["Q8NGN3"],"Chromosome":"11","Position":"124012997-124018732","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10G6","Gene synonym":["OR10G6P","OR10G6Q"],"Ensembl":"ENSG00000198674","Gene description":"Olfactory receptor family 10 subfamily G member 6","Uniprot":["Q8NH81"],"Chromosome":"11","Position":"123994163-123995161","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10G7","Gene synonym":[],"Ensembl":"ENSG00000182634","Gene description":"Olfactory receptor family 10 subfamily G member 7","Uniprot":["Q8NGN6"],"Chromosome":"11","Position":"124036013-124041325","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10G8","Gene synonym":[],"Ensembl":"ENSG00000234560","Gene description":"Olfactory receptor family 10 subfamily G member 8","Uniprot":["Q8NGN5"],"Chromosome":"11","Position":"124026798-124030634","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10G9","Gene synonym":["OR10G10P"],"Ensembl":"ENSG00000236981","Gene description":"Olfactory receptor family 10 subfamily G member 9","Uniprot":["Q8NGN4"],"Chromosome":"11","Position":"124023013-124023948","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10H1","Gene synonym":[],"Ensembl":"ENSG00000186723","Gene description":"Olfactory receptor family 10 subfamily H member 1","Uniprot":["Q9Y4A9"],"Chromosome":"19","Position":"15804549-15815664","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"2.8","Endometrial ciliated cells":"1.5","Glandular and luminal cells":"2.6","granulocytes":"2.1","Langerhans cells":"2.0","Melanocytes":"1.7","Spermatocytes":"2.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"1.4","neutrophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"}},{"Gene":"OR10H2","Gene synonym":[],"Ensembl":"ENSG00000171942","Gene description":"Olfactory receptor family 10 subfamily H member 2","Uniprot":["O60403"],"Chromosome":"19","Position":"15728024-15729052","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10H3","Gene synonym":[],"Ensembl":"ENSG00000171936","Gene description":"Olfactory receptor family 10 subfamily H member 3","Uniprot":["O60404"],"Chromosome":"19","Position":"15737985-15742343","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10H4","Gene synonym":[],"Ensembl":"ENSG00000176231","Gene description":"Olfactory receptor family 10 subfamily H member 4","Uniprot":["Q8NGA5"],"Chromosome":"19","Position":"15944299-15950350","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10H5","Gene synonym":[],"Ensembl":"ENSG00000172519","Gene description":"Olfactory receptor family 10 subfamily H member 5","Uniprot":["Q8NGA6"],"Chromosome":"19","Position":"15787661-15800357","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10J1","Gene synonym":["HGMP07J","HSHGMP07J"],"Ensembl":"ENSG00000196184","Gene description":"Olfactory receptor family 10 subfamily J member 1","Uniprot":["P30954"],"Chromosome":"1","Position":"159437845-159443078","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"testis":"7.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Early spermatids":"53.9","Late spermatids":"52.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10J5","Gene synonym":[],"Ensembl":"ENSG00000184155","Gene description":"Olfactory receptor family 10 subfamily J member 5","Uniprot":["Q8NHC4"],"Chromosome":"1","Position":"159535078-159536007","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Angiogenesis","Myogenesis","Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10K1","Gene synonym":[],"Ensembl":"ENSG00000173285","Gene description":"Olfactory receptor family 10 subfamily K member 1","Uniprot":["Q8NGX5"],"Chromosome":"1","Position":"158461574-158470857","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"5.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cholangiocytes":"1.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059125"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059125":"AB_2683913"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10K2","Gene synonym":[],"Ensembl":"ENSG00000180708","Gene description":"Olfactory receptor family 10 subfamily K member 2","Uniprot":["Q6IF99"],"Chromosome":"1","Position":"158418210-158426237","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059125"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059125":"AB_2683913"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10P1","Gene synonym":["OR10P1P","OR10P2P","OR10P3P","OST701"],"Ensembl":"ENSG00000175398","Gene description":"Olfactory receptor family 10 subfamily P member 1","Uniprot":["Q8NGE3"],"Chromosome":"12","Position":"55636860-55637854","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074114"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA074114":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10Q1","Gene synonym":[],"Ensembl":"ENSG00000180475","Gene description":"Olfactory receptor family 10 subfamily Q member 1","Uniprot":["Q8NGQ4"],"Chromosome":"11","Position":"58227882-58228918","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046968"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046968":"AB_2679881"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10R2","Gene synonym":["OR10R2Q"],"Ensembl":"ENSG00000198965","Gene description":"Olfactory receptor family 10 subfamily R member 2","Uniprot":["Q8NGX6"],"Chromosome":"1","Position":"158472220-158480936","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"28","RNA cell line specific nTPM":{"Leukemia":"2.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059775","HPA060399"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059775":"AB_2684124","HPA060399":"AB_2684276"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10S1","Gene synonym":[],"Ensembl":"ENSG00000196248","Gene description":"Olfactory receptor family 10 subfamily S member 1","Uniprot":["Q8NGN2"],"Chromosome":"11","Position":"123976661-123977781","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019038"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019038":"AB_1854785"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10T2","Gene synonym":[],"Ensembl":"ENSG00000186306","Gene description":"Olfactory receptor family 10 subfamily T member 2","Uniprot":["Q8NGX3"],"Chromosome":"1","Position":"158398522-158399466","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10V1","Gene synonym":[],"Ensembl":"ENSG00000172289","Gene description":"Olfactory receptor family 10 subfamily V member 1","Uniprot":["Q8NGI7"],"Chromosome":"11","Position":"59712916-59713845","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Skin - Mast cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060076"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060076":"AB_2684198"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10W1","Gene synonym":["OR10W1P"],"Ensembl":"ENSG00000172772","Gene description":"Olfactory receptor family 10 subfamily W member 1","Uniprot":["Q8NGF6"],"Chromosome":"11","Position":"58266792-58268260","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10X1","Gene synonym":["OR10X1P"],"Ensembl":"ENSG00000279111","Gene description":"Olfactory receptor family 10 subfamily X member 1","Uniprot":["Q8NGY0"],"Chromosome":"1","Position":"158578919-158579899","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR10Z1","Gene synonym":[],"Ensembl":"ENSG00000198967","Gene description":"Olfactory receptor family 10 subfamily Z member 1","Uniprot":["Q8NGY1"],"Chromosome":"1","Position":"158605268-158612514","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"bone marrow":"7.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Erythroid cells":"2.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR11A1","Gene synonym":["hs6M1-18","OR11A2"],"Ensembl":"ENSG00000204694","Gene description":"Olfactory receptor family 11 subfamily A member 1","Uniprot":["Q9GZK7"],"Chromosome":"6","Position":"29425504-29457071","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"87","RNA single cell type specific nTPM":{"Early spermatids":"22.6","Late spermatids":"37.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR11G2","Gene synonym":[],"Ensembl":"ENSG00000196832","Gene description":"Olfactory receptor family 11 subfamily G member 2","Uniprot":["Q8NGC1"],"Chromosome":"14","Position":"20190894-20201075","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"2.2","Kupffer cells":"1.5","NK-cells":"1.4","Serous glandular cells":"2.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"2.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"granulocytes":"2.2"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR11H1","Gene synonym":["OR22-1"],"Ensembl":"ENSG00000130538","Gene description":"Olfactory receptor family 11 subfamily H member 1","Uniprot":[],"Chromosome":"22","Position":"15528192-15529139","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR11H12","Gene synonym":[],"Ensembl":"ENSG00000257115","Gene description":"Olfactory receptor family 11 subfamily H member 12","Uniprot":["B2RN74"],"Chromosome":"14","Position":"18601045-18602129","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047370"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047370":"AB_2680016"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR11H2","Gene synonym":["C14orf15","OR11H2P","OR11H8P"],"Ensembl":"ENSG00000258453","Gene description":"Olfactory receptor family 11 subfamily H member 2","Uniprot":["Q8NH07"],"Chromosome":"14","Position":"19712904-19714332","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047370"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047370":"AB_2680016"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR11H4","Gene synonym":[],"Ensembl":"ENSG00000176198","Gene description":"Olfactory receptor family 11 subfamily H member 4","Uniprot":["Q8NGC9"],"Chromosome":"14","Position":"20239286-20244349","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052790"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 69: BICR 18 - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052790":"AB_2681950"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR11H6","Gene synonym":[],"Ensembl":"ENSG00000176219","Gene description":"Olfactory receptor family 11 subfamily H member 6","Uniprot":["Q8NGC7"],"Chromosome":"14","Position":"20223710-20224702","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR11L1","Gene synonym":[],"Ensembl":"ENSG00000197591","Gene description":"Olfactory receptor family 11 subfamily L member 1","Uniprot":["Q8NGX0"],"Chromosome":"1","Position":"247840928-247841896","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR12D2","Gene synonym":["hs6M1-20"],"Ensembl":"ENSG00000280236","Gene description":"Olfactory receptor family 12 subfamily D member 2","Uniprot":["P58182"],"Chromosome":"6","Position":"29395631-29398008","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"Kidney cancer":"1.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR12D3","Gene synonym":["hs6M1-27"],"Ensembl":"ENSG00000112462","Gene description":"Olfactory receptor family 12 subfamily D member 3","Uniprot":["Q9UGF7"],"Chromosome":"6","Position":"29373423-29375291","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR13A1","Gene synonym":[],"Ensembl":"ENSG00000256574","Gene description":"Olfactory receptor family 13 subfamily A member 1","Uniprot":["Q8NGR1"],"Chromosome":"10","Position":"45302298-45315608","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"urinary bladder":"1.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"0.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"25","RNA cell line specific nTPM":{"lymphoma":"6.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057237"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057237":"AB_2683378"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-3"}},{"Gene":"OR13C2","Gene synonym":[],"Ensembl":"ENSG00000276119","Gene description":"Olfactory receptor family 13 subfamily C member 2","Uniprot":["Q8NGS9"],"Chromosome":"9","Position":"104604671-104605627","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078297"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA078297":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR13C3","Gene synonym":[],"Ensembl":"ENSG00000204246","Gene description":"Olfactory receptor family 13 subfamily C member 3","Uniprot":["Q8NGS6"],"Chromosome":"9","Position":"104535749-104536856","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053978"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053978":"AB_2682330"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR13C4","Gene synonym":[],"Ensembl":"ENSG00000148136","Gene description":"Olfactory receptor family 13 subfamily C member 4","Uniprot":["Q8NGS5"],"Chromosome":"9","Position":"104526253-104527209","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR13C5","Gene synonym":[],"Ensembl":"ENSG00000277556","Gene description":"Olfactory receptor family 13 subfamily C member 5","Uniprot":["Q8NGS8"],"Chromosome":"9","Position":"104598457-104599413","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078297"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA078297":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR13C8","Gene synonym":[],"Ensembl":"ENSG00000186943","Gene description":"Olfactory receptor family 13 subfamily C member 8","Uniprot":["Q8NGS7"],"Chromosome":"9","Position":"104569168-104570130","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR13C9","Gene synonym":[],"Ensembl":"ENSG00000136839","Gene description":"Olfactory receptor family 13 subfamily C member 9","Uniprot":["Q8NGT0"],"Chromosome":"9","Position":"104617248-104618204","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078297"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA078297":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR13D1","Gene synonym":[],"Ensembl":"ENSG00000179055","Gene description":"Olfactory receptor family 13 subfamily D member 1","Uniprot":["Q8NGV5"],"Chromosome":"9","Position":"104694379-104695485","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055921"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055921":"AB_2682970"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR13F1","Gene synonym":[],"Ensembl":"ENSG00000186881","Gene description":"Olfactory receptor family 13 subfamily F member 1","Uniprot":["Q8NGS4"],"Chromosome":"9","Position":"104504263-104505222","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR13G1","Gene synonym":[],"Ensembl":"ENSG00000197437","Gene description":"Olfactory receptor family 13 subfamily G member 1","Uniprot":["Q8NGZ3"],"Chromosome":"1","Position":"247670812-247679739","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR13H1","Gene synonym":[],"Ensembl":"ENSG00000171054","Gene description":"Olfactory receptor family 13 subfamily H member 1","Uniprot":["Q8NG92"],"Chromosome":"X","Position":"131543976-131545056","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR13J1","Gene synonym":[],"Ensembl":"ENSG00000168828","Gene description":"Olfactory receptor family 13 subfamily J member 1","Uniprot":["Q8NGT2"],"Chromosome":"9","Position":"35869263-35870601","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"1.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"1.0"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR14A16","Gene synonym":["OR5AT1"],"Ensembl":"ENSG00000196772","Gene description":"Olfactory receptor family 14 subfamily A member 16","Uniprot":["Q8NHC5"],"Chromosome":"1","Position":"247814660-247824119","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR14A2","Gene synonym":["OR5AX1","OR5AX1P"],"Ensembl":"ENSG00000241128","Gene description":"Olfactory receptor family 14 subfamily A member 2","Uniprot":["Q96R54"],"Chromosome":"1","Position":"247722957-247724043","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"testis":"2.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"17.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052685"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052685":"AB_2681914"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR14C36","Gene synonym":["OR5BF1"],"Ensembl":"ENSG00000177174","Gene description":"Olfactory receptor family 14 subfamily C member 36","Uniprot":["Q8NHC7"],"Chromosome":"1","Position":"248348775-248349713","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR14I1","Gene synonym":["OR5BU1","OR5BU1P"],"Ensembl":"ENSG00000189181","Gene description":"Olfactory receptor family 14 subfamily I member 1","Uniprot":["A6ND48"],"Chromosome":"1","Position":"248681322-248682328","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Excitatory neurons":"29.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR14J1","Gene synonym":["hs6M1-28","OR5U1"],"Ensembl":"ENSG00000204695","Gene description":"Olfactory receptor family 14 subfamily J member 1","Uniprot":["Q9UGF5"],"Chromosome":"6","Position":"29301701-29313017","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.2","retina":"2.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Skeletal myocytes":"2.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR14K1","Gene synonym":["OR5AY1"],"Ensembl":"ENSG00000153230","Gene description":"Olfactory receptor family 14 subfamily K member 1","Uniprot":["Q8NGZ2"],"Chromosome":"1","Position":"247738615-247739559","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016643"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016643":"AB_1854788"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR14L1P","Gene synonym":["OR5AV1","OR5AV1P"],"Ensembl":"ENSG00000198452","Gene description":"Olfactory receptor family 14 subfamily L member 1 pseudogene","Uniprot":[],"Chromosome":"1","Position":"247617143-247622372","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1.1","granulocytes":"6.3","Late spermatids":"2.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.0"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"53","RNA blood cell specific nTPM":{"basophil":"5.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"53","RNA blood lineage specific nTPM":{"granulocytes":"5.2"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1A1","Gene synonym":["OR17-7"],"Ensembl":"ENSG00000172146","Gene description":"Olfactory receptor family 1 subfamily A member 1","Uniprot":["Q9P1Q5"],"Chromosome":"17","Position":"3207539-3218896","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"6.4"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1A2","Gene synonym":["OR17-6"],"Ensembl":"ENSG00000172150","Gene description":"Olfactory receptor family 1 subfamily A member 2","Uniprot":["Q9Y585"],"Chromosome":"17","Position":"3197519-3198448","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1B1","Gene synonym":["OR9-B"],"Ensembl":"ENSG00000280094","Gene description":"Olfactory receptor family 1 subfamily B member 1","Uniprot":["Q8NGR6"],"Chromosome":"9","Position":"122628579-122629573","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1C1","Gene synonym":["HSTPCR27","TPCR27"],"Ensembl":"ENSG00000221888","Gene description":"Olfactory receptor family 1 subfamily C member 1","Uniprot":["Q15619"],"Chromosome":"1","Position":"247754846-247760556","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"2.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1D2","Gene synonym":["OLFR1","OR17-4"],"Ensembl":"ENSG00000184166","Gene description":"Olfactory receptor family 1 subfamily D member 2","Uniprot":["P34982"],"Chromosome":"17","Position":"3088484-3104422","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Chemotaxis","Fertilization","Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7","Early spermatids":"1.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1D5","Gene synonym":["OR17-31"],"Ensembl":"ENSG00000262628","Gene description":"Olfactory receptor family 1 subfamily D member 5","Uniprot":["P58170"],"Chromosome":"17","Position":"3062669-3063607","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1E1","Gene synonym":["HGM071","OR13-66","OR17-2","OR17-32","OR1E5","OR1E6","OR1E9P"],"Ensembl":"ENSG00000180016","Gene description":"Olfactory receptor family 1 subfamily E member 1","Uniprot":["P30953"],"Chromosome":"17","Position":"3397104-3398410","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1E2","Gene synonym":["OR17-135","OR17-93","OR1E4"],"Ensembl":"ENSG00000127780","Gene description":"Olfactory receptor family 1 subfamily E member 2","Uniprot":["P47887"],"Chromosome":"17","Position":"3432870-3433841","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"1.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"white matter":"1.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1F1","Gene synonym":["Olfmf","OR16-36","OR16-37","OR16-88","OR16-89","OR16-90","OR1F10","OR1F13P","OR1F4","OR1F5","OR1F6","OR1F7","OR1F8","OR1F9","OR3-145"],"Ensembl":"ENSG00000168124","Gene description":"Olfactory receptor family 1 subfamily F member 1","Uniprot":["O43749"],"Chromosome":"16","Position":"3204247-3205188","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"2.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Early spermatids":"3.0","Excitatory neurons":"1.3","Inhibitory neurons":"1.2","Late spermatids":"3.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1G1","Gene synonym":["OR17-209","OR1G2"],"Ensembl":"ENSG00000183024","Gene description":"Olfactory receptor family 1 subfamily G member 1","Uniprot":["P47890"],"Chromosome":"17","Position":"3126584-3127581","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1I1","Gene synonym":["OR19-20","OR1I1P","OR1I1Q"],"Ensembl":"ENSG00000094661","Gene description":"Olfactory receptor family 1 subfamily I member 1","Uniprot":["O60431"],"Chromosome":"19","Position":"15082211-15092970","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"2.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1J1","Gene synonym":["hg32"],"Ensembl":"ENSG00000136834","Gene description":"Olfactory receptor family 1 subfamily J member 1","Uniprot":["Q8NGS3"],"Chromosome":"9","Position":"122476958-122477926","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"}},{"Gene":"OR1J2","Gene synonym":["OR1J3","OR1J5","OST044"],"Ensembl":"ENSG00000197233","Gene description":"Olfactory receptor family 1 subfamily J member 2","Uniprot":["Q8NGS2"],"Chromosome":"9","Position":"122510802-122511743","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Excitatory neurons":"14.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1J4","Gene synonym":["HSHTPCRX01","HTPCRX01"],"Ensembl":"ENSG00000239590","Gene description":"Olfactory receptor family 1 subfamily J member 4","Uniprot":["Q8NGS1"],"Chromosome":"9","Position":"122519141-122520082","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-1"}},{"Gene":"OR1K1","Gene synonym":["hg99","MNAB"],"Ensembl":"ENSG00000165204","Gene description":"Olfactory receptor family 1 subfamily K member 1","Uniprot":["Q8NGR3"],"Chromosome":"9","Position":"122800123-122801073","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1L1","Gene synonym":["OR1L2","OR9-C"],"Ensembl":"ENSG00000173679","Gene description":"Olfactory receptor family 1 subfamily L member 1","Uniprot":["Q8NH94"],"Chromosome":"9","Position":"122661566-122662648","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1L3","Gene synonym":["OR9-D"],"Ensembl":"ENSG00000171481","Gene description":"Olfactory receptor family 1 subfamily L member 3","Uniprot":["Q8NH93"],"Chromosome":"9","Position":"122675036-122676153","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058878"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058878":"AB_2683843"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1L4","Gene synonym":["OR1L5","OR9-E"],"Ensembl":"ENSG00000136939","Gene description":"Olfactory receptor family 1 subfamily L member 4","Uniprot":["Q8NGR5"],"Chromosome":"9","Position":"122723990-122724925","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1L6","Gene synonym":["OR1L7"],"Ensembl":"ENSG00000171459","Gene description":"Olfactory receptor family 1 subfamily L member 6","Uniprot":["Q8NGR2"],"Chromosome":"9","Position":"122742303-122750783","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1L8","Gene synonym":[],"Ensembl":"ENSG00000171496","Gene description":"Olfactory receptor family 1 subfamily L member 8","Uniprot":["Q8NGR8"],"Chromosome":"9","Position":"122567117-122583384","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"4.4","Excitatory neurons":"8.5","Inhibitory neurons":"5.0","Oligodendrocyte precursor cells":"2.9","Oligodendrocytes":"7.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"OR1M1","Gene synonym":["OR19-6"],"Ensembl":"ENSG00000170929","Gene description":"Olfactory receptor family 1 subfamily M member 1","Uniprot":["Q8NGA1"],"Chromosome":"19","Position":"9087061-9095669","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1N1","Gene synonym":["OR1-26","OR1N3"],"Ensembl":"ENSG00000171505","Gene description":"Olfactory receptor family 1 subfamily N member 1","Uniprot":["Q8NGS0"],"Chromosome":"9","Position":"122526358-122527296","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"endometrial cancer":"0.8","ovarian cancer":"1.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1N2","Gene synonym":[],"Ensembl":"ENSG00000171501","Gene description":"Olfactory receptor family 1 subfamily N member 2","Uniprot":["Q8NGR9"],"Chromosome":"9","Position":"122553112-122555173","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1Q1","Gene synonym":["HSTPCR106","OR1Q2","OR1Q3","OR9-A","OST226","OST226OR9-A","TPCR106"],"Ensembl":"ENSG00000165202","Gene description":"Olfactory receptor family 1 subfamily Q member 1","Uniprot":["Q15612"],"Chromosome":"9","Position":"122614738-122615682","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"1.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Excitatory neurons":"8.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044828"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044828":"AB_10960565"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"}},{"Gene":"OR1R1P","Gene synonym":["OR17-1","OR1R2P","OR1R3P","OR20A1P"],"Ensembl":"ENSG00000180042","Gene description":"Olfactory receptor family 1 subfamily R member 1 pseudogene","Uniprot":[],"Chromosome":"17","Position":"3385930-3386874","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Collecting duct cells":"2.0","Early spermatids":"7.2","Late spermatids":"3.3","Sertoli cells":"2.8","Spermatocytes":"5.6","Spermatogonia":"1.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"plasmacytoid DC":"1.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"1.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1S1","Gene synonym":["OST034"],"Ensembl":"ENSG00000280204","Gene description":"Olfactory receptor family 1 subfamily S member 1","Uniprot":["Q8NH92"],"Chromosome":"11","Position":"58212720-58216084","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049304"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049304":"AB_2680704"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR1S2","Gene synonym":[],"Ensembl":"ENSG00000197887","Gene description":"Olfactory receptor family 1 subfamily S member 2","Uniprot":["Q8NGQ3"],"Chromosome":"11","Position":"58203202-58204181","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049304"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049304":"AB_2680704"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2A1","Gene synonym":[],"Ensembl":"ENSG00000221970","Gene description":"Olfactory receptor family 2 subfamily A member 1","Uniprot":["Q8NGT9"],"Chromosome":"7","Position":"144312419-144322737","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"2.4"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058272"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058272":"AB_2683662"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2A12","Gene synonym":["OR2A12P"],"Ensembl":"ENSG00000221858","Gene description":"Olfactory receptor family 2 subfamily A member 12","Uniprot":["Q8NGT7"],"Chromosome":"7","Position":"144086278-144098953","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2A14","Gene synonym":["OR2A14P","OR2A6","OST182"],"Ensembl":"ENSG00000221938","Gene description":"Olfactory receptor family 2 subfamily A member 14","Uniprot":["Q96R47"],"Chromosome":"7","Position":"144123176-144131188","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2A2","Gene synonym":["OR2A17P","OR2A2P","OST008"],"Ensembl":"ENSG00000221989","Gene description":"Olfactory receptor family 2 subfamily A member 2","Uniprot":["Q6IF42"],"Chromosome":"7","Position":"144109514-144110564","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2A25","Gene synonym":["OR2A25P","OR2A27"],"Ensembl":"ENSG00000221933","Gene description":"Olfactory receptor family 2 subfamily A member 25","Uniprot":["A4D2G3"],"Chromosome":"7","Position":"144069811-144075870","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"NK-cells":"18.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058272"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058272":"AB_2683662"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2A4","Gene synonym":["OR2A10"],"Ensembl":"ENSG00000180658","Gene description":"Olfactory receptor family 2 subfamily A member 4","Uniprot":["O95047"],"Chromosome":"6","Position":"131699644-131701401","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"renal cancer":"0.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"12.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"12.0"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058272"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058272":"AB_2683662"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2A42","Gene synonym":[],"Ensembl":"ENSG00000212807","Gene description":"Olfactory receptor family 2 subfamily A member 42","Uniprot":["Q8NGT9"],"Chromosome":"7","Position":"144228244-144239605","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"1.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058272"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058272":"AB_2683662"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2A5","Gene synonym":["OR2A26","OR2A8","OR7-138","OR7-141"],"Ensembl":"ENSG00000221836","Gene description":"Olfactory receptor family 2 subfamily A member 5","Uniprot":["Q96R48"],"Chromosome":"7","Position":"144048948-144058845","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2A7","Gene synonym":["HSDJ0798C17"],"Ensembl":"ENSG00000243896","Gene description":"Olfactory receptor family 2 subfamily A member 7","Uniprot":["Q96R45"],"Chromosome":"7","Position":"144257663-144264792","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"12.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"12.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058272"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058272":"AB_2683662"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"}},{"Gene":"OR2AE1","Gene synonym":["OR2AE2"],"Ensembl":"ENSG00000244623","Gene description":"Olfactory receptor family 2 subfamily AE member 1","Uniprot":["Q8NHA4"],"Chromosome":"7","Position":"99875987-99877057","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042957"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042957":"AB_10794539"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2AG1","Gene synonym":["OR2AG3"],"Ensembl":"ENSG00000279486","Gene description":"Olfactory receptor family 2 subfamily AG member 1","Uniprot":["Q9H205"],"Chromosome":"11","Position":"6783020-6791558","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"3.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2AG2","Gene synonym":["OR2AG2P"],"Ensembl":"ENSG00000188124","Gene description":"Olfactory receptor family 2 subfamily AG member 2","Uniprot":["A6NM03"],"Chromosome":"11","Position":"6765626-6771976","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"117.3","Inhibitory neurons":"61.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2AJ1","Gene synonym":["OR2AJ1P","OR2AJ1Q"],"Ensembl":"ENSG00000177275","Gene description":"Olfactory receptor family 2 subfamily AJ member 1","Uniprot":["Q8NGZ0"],"Chromosome":"1","Position":"247924889-247935339","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2AK2","Gene synonym":["OR2AK1P"],"Ensembl":"ENSG00000187080","Gene description":"Olfactory receptor family 2 subfamily AK member 2","Uniprot":[],"Chromosome":"1","Position":"247965233-247966386","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2AP1","Gene synonym":["OR2AP1P"],"Ensembl":"ENSG00000179615","Gene description":"Olfactory receptor family 2 subfamily AP member 1","Uniprot":["Q8NGE2"],"Chromosome":"12","Position":"55572468-55575612","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2AT4","Gene synonym":[],"Ensembl":"ENSG00000171561","Gene description":"Olfactory receptor family 2 subfamily AT member 4","Uniprot":["A6NND4"],"Chromosome":"11","Position":"75081753-75096876","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.2","retina":"1.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7","Early spermatids":"2.2","Late spermatids":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2B11","Gene synonym":[],"Ensembl":"ENSG00000177535","Gene description":"Olfactory receptor family 2 subfamily B member 11","Uniprot":["Q5JQS5"],"Chromosome":"1","Position":"247449118-247458105","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7","Horizontal cells":"1.3","Macrophages":"1.7","monocytes":"6.7","Schwann cells":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047459"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047459":"AB_10963692"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2B2","Gene synonym":["hs6M1-10","OR2B2Q","OR2B9","OR6-1"],"Ensembl":"ENSG00000168131","Gene description":"Olfactory receptor family 2 subfamily B member 2","Uniprot":["Q9GZK3"],"Chromosome":"6","Position":"27911185-27912396","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2B3","Gene synonym":["OR2B3P","OR6-4"],"Ensembl":"ENSG00000204703","Gene description":"Olfactory receptor family 2 subfamily B member 3","Uniprot":["O76000"],"Chromosome":"6","Position":"29086208-29087313","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2B6","Gene synonym":["dJ408B20.2","OR2B1","OR2B1P","OR2B5","OR2B6P","OR5-40","OR5-41","OR6-31"],"Ensembl":"ENSG00000124657","Gene description":"Olfactory receptor family 2 subfamily B member 6","Uniprot":["P58173"],"Chromosome":"6","Position":"27957241-27958182","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"1.1","Syncytiotrophoblasts":"1.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 1: Non-specific - Nucleosome assembly","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-3"}},{"Gene":"OR2C1","Gene synonym":["OLFmf3","OR2C2P"],"Ensembl":"ENSG00000168158","Gene description":"Olfactory receptor family 2 subfamily C member 1","Uniprot":["O95371"],"Chromosome":"16","Position":"3355889-3357306","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2C3","Gene synonym":["OR2C4","OR2C5P","OST742"],"Ensembl":"ENSG00000196242","Gene description":"Olfactory receptor family 2 subfamily C member 3","Uniprot":["Q8N628"],"Chromosome":"1","Position":"247524677-247536440","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.3","testis":"1.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"3.9","granulocytes":"1.6","Late spermatids":"4.6","Spermatocytes":"5.7","Spermatogonia":"2.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.3"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"1.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058578"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA058578":"AB_2683761"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2D2","Gene synonym":["hg27","OR11-610","OR2D1"],"Ensembl":"ENSG00000166368","Gene description":"Olfactory receptor family 2 subfamily D member 2","Uniprot":["Q9H210"],"Chromosome":"11","Position":"6891490-6892599","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2D3","Gene synonym":[],"Ensembl":"ENSG00000178358","Gene description":"Olfactory receptor family 2 subfamily D member 3","Uniprot":["Q8NGH3"],"Chromosome":"11","Position":"6920974-6922043","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052551"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052551":"AB_2681867"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2F1","Gene synonym":["OLF3","OR14-60","OR2F3","OR2F3P","OR2F4","OR2F5","OR7-139","OR7-140"],"Ensembl":"ENSG00000213215","Gene description":"Olfactory receptor family 2 subfamily F member 1","Uniprot":["Q13607"],"Chromosome":"7","Position":"143954844-143997312","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7","Cytotrophoblasts":"5.1","Early spermatids":"1.5","Late spermatids":"2.8","Spermatocytes":"1.8","Syncytiotrophoblasts":"7.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2F2","Gene synonym":["OR7-1"],"Ensembl":"ENSG00000221910","Gene description":"Olfactory receptor family 2 subfamily F member 2","Uniprot":["O95006"],"Chromosome":"7","Position":"143935166-143936279","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2G2","Gene synonym":[],"Ensembl":"ENSG00000177489","Gene description":"Olfactory receptor family 2 subfamily G member 2","Uniprot":["Q8NGZ5"],"Chromosome":"1","Position":"247588360-247589313","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2G3","Gene synonym":[],"Ensembl":"ENSG00000177476","Gene description":"Olfactory receptor family 2 subfamily G member 3","Uniprot":["Q8NGZ4"],"Chromosome":"1","Position":"247605586-247606515","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2G6","Gene synonym":[],"Ensembl":"ENSG00000188558","Gene description":"Olfactory receptor family 2 subfamily G member 6","Uniprot":["Q5TZ20"],"Chromosome":"1","Position":"248508073-248527337","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2H1","Gene synonym":["OR2H6","OR2H8","OR6-2"],"Ensembl":"ENSG00000204688","Gene description":"Olfactory receptor family 2 subfamily H member 1","Uniprot":["Q9GZK4"],"Chromosome":"6","Position":"29457181-29464328","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"127","RNA tissue specific nTPM":{"testis":"12.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Early spermatids":"55.4","Late spermatids":"28.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2H2","Gene synonym":["hs6M1-12"],"Ensembl":"ENSG00000204657","Gene description":"Olfactory receptor family 2 subfamily H member 2","Uniprot":["O95918"],"Chromosome":"6","Position":"29585121-29590500","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.8","epididymis":"4.8","testis":"2.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Early spermatids":"13.9","Late spermatids":"6.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"1.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2I1P","Gene synonym":["HS6M1-14","OR2I1","OR2I2","OR2I3P","OR2I4P"],"Ensembl":"ENSG00000237988","Gene description":"Olfactory receptor family 2 subfamily I member 1 pseudogene","Uniprot":[],"Chromosome":"6","Position":"29550407-29557721","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"1.9","Rod photoreceptor cells":"2.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"71.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - T-cells","Pancreas - Ductal cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.29e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.58e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.00e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"}},{"Gene":"OR2J1","Gene synonym":["dJ80I19.2","hs6M1-4","OR2J1P","OR6-5"],"Ensembl":"ENSG00000204702","Gene description":"Olfactory receptor family 2 subfamily J member 1","Uniprot":["Q9GZK6"],"Chromosome":"6","Position":"29099657-29102701","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2J2","Gene synonym":["dJ80I19.4","hs6M1-6","OR6-8"],"Ensembl":"ENSG00000204700","Gene description":"Olfactory receptor family 2 subfamily J member 2","Uniprot":["O76002"],"Chromosome":"6","Position":"29170907-29175811","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"1.6","Late spermatids":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2J3","Gene synonym":["OR6-6"],"Ensembl":"ENSG00000204701","Gene description":"Olfactory receptor family 2 subfamily J member 3","Uniprot":["O76001"],"Chromosome":"6","Position":"29108058-29114770","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"4.3","Late spermatids":"1.9","Spermatocytes":"2.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2K2","Gene synonym":["HSHTPCRH06","HTPCRH06","OR2AR1P"],"Ensembl":"ENSG00000171133","Gene description":"Olfactory receptor family 2 subfamily K member 2","Uniprot":["Q8NGT1"],"Chromosome":"9","Position":"111327483-111330183","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024261"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024261":"AB_1854786"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2L13","Gene synonym":["OR2L14"],"Ensembl":"ENSG00000196071","Gene description":"Olfactory receptor family 2 subfamily L member 13","Uniprot":["Q8N349"],"Chromosome":"1","Position":"248095184-248101103","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"6.7","retina":"2.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"19","RNA single cell type specific nTPM":{"Excitatory neurons":"138.4","Inhibitory neurons":"104.4","Oligodendrocyte precursor cells":"65.5","Oligodendrocytes":"131.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2L2","Gene synonym":["HSHTPCRH07","HTPCRH07","OR2L12","OR2L4P"],"Ensembl":"ENSG00000203663","Gene description":"Olfactory receptor family 2 subfamily L member 2","Uniprot":["Q8NH16"],"Chromosome":"1","Position":"248030070-248042305","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.3","retina":"1.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.7","Collecting duct cells":"2.0","Early spermatids":"7.1","Langerhans cells":"2.0","Late spermatids":"5.2","Leydig cells":"1.7","Rod photoreceptor cells":"1.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2L3","Gene synonym":[],"Ensembl":"ENSG00000198128","Gene description":"Olfactory receptor family 2 subfamily L member 3","Uniprot":["Q8NG85"],"Chromosome":"1","Position":"248046836-248063407","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2L5","Gene synonym":["OR2L11","OR2L5P"],"Ensembl":"ENSG00000197454","Gene description":"Olfactory receptor family 2 subfamily L member 5","Uniprot":["Q8NG80"],"Chromosome":"1","Position":"248013660-248024276","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"1.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2L8","Gene synonym":[],"Ensembl":"ENSG00000279263","Gene description":"Olfactory receptor family 2 subfamily L member 8","Uniprot":["Q8NGY9"],"Chromosome":"1","Position":"247948858-247949796","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"brain":"1.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2M2","Gene synonym":["OR2M2Q","OST423"],"Ensembl":"ENSG00000198601","Gene description":"Olfactory receptor family 2 subfamily M member 2","Uniprot":["Q96R28"],"Chromosome":"1","Position":"248174821-248181067","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2M3","Gene synonym":["OR2M3P","OR2M6","OST003"],"Ensembl":"ENSG00000228198","Gene description":"Olfactory receptor family 2 subfamily M member 3","Uniprot":["Q8NG83"],"Chromosome":"1","Position":"248197265-248212925","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.4","Horizontal cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2M4","Gene synonym":["HSHTPCRX18","HTPCRX18","OST710","TPCR100"],"Ensembl":"ENSG00000171180","Gene description":"Olfactory receptor family 2 subfamily M member 4","Uniprot":["Q96R27"],"Chromosome":"1","Position":"248231417-248244679","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1.5","Horizontal cells":"1.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051308"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051308":"AB_2681435"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2M5","Gene synonym":["OR2M5P"],"Ensembl":"ENSG00000162727","Gene description":"Olfactory receptor family 2 subfamily M member 5","Uniprot":["A3KFT3"],"Chromosome":"1","Position":"248145148-248146086","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2M7","Gene synonym":[],"Ensembl":"ENSG00000177186","Gene description":"Olfactory receptor family 2 subfamily M member 7","Uniprot":["Q8NG81"],"Chromosome":"1","Position":"248323630-248324568","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2S2","Gene synonym":[],"Ensembl":"ENSG00000278889","Gene description":"Olfactory receptor family 2 subfamily S member 2","Uniprot":["Q9NQN1"],"Chromosome":"9","Position":"35957108-35958154","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T1","Gene synonym":["OR1-25"],"Ensembl":"ENSG00000175143","Gene description":"Olfactory receptor family 2 subfamily T member 1","Uniprot":[],"Chromosome":"1","Position":"248403048-248408020","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T10","Gene synonym":[],"Ensembl":"ENSG00000184022","Gene description":"Olfactory receptor family 2 subfamily T member 10","Uniprot":["Q8NGZ9"],"Chromosome":"1","Position":"248590487-248597700","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"kidney":"5.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"B-cells":"1.3","Proximal tubular cells":"3.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"0.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052019"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052019":"AB_2681696"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T11","Gene synonym":["OR2T11Q"],"Ensembl":"ENSG00000279301","Gene description":"Olfactory receptor family 2 subfamily T member 11","Uniprot":["Q8NH01"],"Chromosome":"1","Position":"248623557-248635091","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T12","Gene synonym":[],"Ensembl":"ENSG00000177201","Gene description":"Olfactory receptor family 2 subfamily T member 12","Uniprot":["Q8NG77"],"Chromosome":"1","Position":"248290139-248303424","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"2.9","Horizontal cells":"1.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T2","Gene synonym":["OR2T2P"],"Ensembl":"ENSG00000196240","Gene description":"Olfactory receptor family 2 subfamily T member 2","Uniprot":["Q6IF00"],"Chromosome":"1","Position":"248445512-248455725","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal tubular cells":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T27","Gene synonym":[],"Ensembl":"ENSG00000187701","Gene description":"Olfactory receptor family 2 subfamily T member 27","Uniprot":["Q8NH04"],"Chromosome":"1","Position":"248649838-248655528","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T29","Gene synonym":[],"Ensembl":"ENSG00000182783","Gene description":"Olfactory receptor family 2 subfamily T member 29","Uniprot":["Q8NH02"],"Chromosome":"1","Position":"248556912-248562772","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T3","Gene synonym":[],"Ensembl":"ENSG00000196539","Gene description":"Olfactory receptor family 2 subfamily T member 3","Uniprot":["Q8NH03"],"Chromosome":"1","Position":"248473351-248474307","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T33","Gene synonym":[],"Ensembl":"ENSG00000177212","Gene description":"Olfactory receptor family 2 subfamily T member 33","Uniprot":["Q8NG76"],"Chromosome":"1","Position":"248269917-248277976","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T34","Gene synonym":[],"Ensembl":"ENSG00000183310","Gene description":"Olfactory receptor family 2 subfamily T member 34","Uniprot":["Q8NGX1"],"Chromosome":"1","Position":"248573801-248574757","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T35","Gene synonym":[],"Ensembl":"ENSG00000177151","Gene description":"Olfactory receptor family 2 subfamily T member 35","Uniprot":["Q8NGX2"],"Chromosome":"1","Position":"248636356-248645278","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T4","Gene synonym":["OR2T4Q"],"Ensembl":"ENSG00000196944","Gene description":"Olfactory receptor family 2 subfamily T member 4","Uniprot":["Q8NH00"],"Chromosome":"1","Position":"248361581-248362627","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T5","Gene synonym":[],"Ensembl":"ENSG00000203661","Gene description":"Olfactory receptor family 2 subfamily T member 5","Uniprot":["Q6IEZ7"],"Chromosome":"1","Position":"248488589-248491113","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T6","Gene synonym":["OR2T6P","OR2T9","OST703"],"Ensembl":"ENSG00000198104","Gene description":"Olfactory receptor family 2 subfamily T member 6","Uniprot":["Q8NHC8"],"Chromosome":"1","Position":"248375746-248391811","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2T8","Gene synonym":["OR2T8P"],"Ensembl":"ENSG00000177462","Gene description":"Olfactory receptor family 2 subfamily T member 8","Uniprot":["A6NH00"],"Chromosome":"1","Position":"247920252-247923152","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"1.5","Early spermatids":"1.4","Erythroid cells":"1.9","Excitatory neurons":"4.9","Inhibitory neurons":"1.3","Spermatocytes":"1.4","Spermatogonia":"1.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2V1","Gene synonym":["OR2V1P","OST265"],"Ensembl":"ENSG00000185372","Gene description":"Olfactory receptor family 2 subfamily V member 1","Uniprot":["Q8NHB1"],"Chromosome":"5","Position":"181123122-181131169","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"1.6","retina":"1.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049953"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049953":"AB_2680971"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2V2","Gene synonym":["OR2V3","OST713"],"Ensembl":"ENSG00000182613","Gene description":"Olfactory receptor family 2 subfamily V member 2","Uniprot":["Q96R30"],"Chromosome":"5","Position":"181147586-181159285","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049953"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049953":"AB_2680971"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2W1","Gene synonym":["hs6M1-15"],"Ensembl":"ENSG00000204704","Gene description":"Olfactory receptor family 2 subfamily W member 1","Uniprot":["Q9Y3N9"],"Chromosome":"6","Position":"29044213-29045240","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2W3","Gene synonym":["OR2W3P","OR2W8P","OST718"],"Ensembl":"ENSG00000238243","Gene description":"Olfactory receptor family 2 subfamily W member 3","Uniprot":["Q7Z3T1"],"Chromosome":"1","Position":"247895587-247896531","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"13.0","brain":"6.1","thyroid gland":"6.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"2.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"8.3"},"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045594"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045594":"AB_10960280"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"}},{"Gene":"OR2Y1","Gene synonym":[],"Ensembl":"ENSG00000174339","Gene description":"Olfactory receptor family 2 subfamily Y member 1","Uniprot":["Q8NGV0"],"Chromosome":"5","Position":"180739042-180740099","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR2Z1","Gene synonym":["OR2Z2"],"Ensembl":"ENSG00000181733","Gene description":"Olfactory receptor family 2 subfamily Z member 1","Uniprot":["Q8NG97"],"Chromosome":"19","Position":"8721634-8732160","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048760"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048760":"AB_2680513"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR3A1","Gene synonym":["OLFRA03","OR17-40","OR40"],"Ensembl":"ENSG00000180090","Gene description":"Olfactory receptor family 3 subfamily A member 1","Uniprot":["P47881"],"Chromosome":"17","Position":"3291017-3298360","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"6.3","Excitatory neurons":"6.8","Microglial cells":"18.2","Oligodendrocyte precursor cells":"2.4","Oligodendrocytes":"5.0","Spermatogonia":"2.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR3A2","Gene synonym":["OLFRA04","OR17-228","OR228"],"Ensembl":"ENSG00000221882","Gene description":"Olfactory receptor family 3 subfamily A member 2","Uniprot":["P47893"],"Chromosome":"17","Position":"3276942-3386317","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"3.3","retina":"1.1","testis":"3.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.1","Early spermatids":"1.0","Late spermatids":"1.9","Spermatocytes":"5.8","Spermatogonia":"2.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"2.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR3A3","Gene synonym":["OR17-137","OR17-16","OR17-201","OR3A6","OR3A7","OR3A8P"],"Ensembl":"ENSG00000159961","Gene description":"Olfactory receptor family 3 subfamily A member 3","Uniprot":["P47888"],"Chromosome":"17","Position":"3411370-3424070","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.4","dendritic cells":"3.6","Horizontal cells":"1.9","Langerhans cells":"2.7","Melanocytes":"1.7","Rod photoreceptor cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"24","RNA blood cell specific nTPM":{"plasmacytoid DC":"7.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"24","RNA blood lineage specific nTPM":{"dendritic cells":"7.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4A15","Gene synonym":[],"Ensembl":"ENSG00000181958","Gene description":"Olfactory receptor family 4 subfamily A member 15","Uniprot":[],"Chromosome":"11","Position":"55367974-55368918","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4A16","Gene synonym":["OR4A16Q"],"Ensembl":"ENSG00000181961","Gene description":"Olfactory receptor family 4 subfamily A member 16","Uniprot":["Q8NH70"],"Chromosome":"11","Position":"55343151-55344231","Protein class":["Cancer-related genes","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4A47","Gene synonym":[],"Ensembl":"ENSG00000237388","Gene description":"Olfactory receptor family 4 subfamily A member 47","Uniprot":["Q6IF82"],"Chromosome":"11","Position":"48488717-48489780","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059763"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059763":"AB_2684122"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4A5","Gene synonym":[],"Ensembl":"ENSG00000221840","Gene description":"Olfactory receptor family 4 subfamily A member 5","Uniprot":["Q8NH83"],"Chromosome":"11","Position":"54706832-54707902","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4B1","Gene synonym":["OST208"],"Ensembl":"ENSG00000175619","Gene description":"Olfactory receptor family 4 subfamily B member 1","Uniprot":["Q8NGF8"],"Chromosome":"11","Position":"48216810-48217739","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059443"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059443":"AB_2684019"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4C11","Gene synonym":["OR4C11P"],"Ensembl":"ENSG00000172188","Gene description":"Olfactory receptor family 4 subfamily C member 11","Uniprot":["Q6IEV9"],"Chromosome":"11","Position":"55602360-55607645","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4C12","Gene synonym":[],"Ensembl":"ENSG00000221954","Gene description":"Olfactory receptor family 4 subfamily C member 12","Uniprot":["Q96R67"],"Chromosome":"11","Position":"49981473-49982535","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4C13","Gene synonym":[],"Ensembl":"ENSG00000258817","Gene description":"Olfactory receptor family 4 subfamily C member 13","Uniprot":["Q8NGP0"],"Chromosome":"11","Position":"49952391-49953419","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4C15","Gene synonym":[],"Ensembl":"ENSG00000181939","Gene description":"Olfactory receptor family 4 subfamily C member 15","Uniprot":["Q8NGM1"],"Chromosome":"11","Position":"55554307-55555419","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061939"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA061939":"AB_2684643"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4C16","Gene synonym":[],"Ensembl":"ENSG00000279514","Gene description":"Olfactory receptor family 4 subfamily C member 16","Uniprot":["Q8NGL9"],"Chromosome":"11","Position":"55572128-55573060","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4C3","Gene synonym":[],"Ensembl":"ENSG00000176547","Gene description":"Olfactory receptor family 4 subfamily C member 3","Uniprot":["Q8NH37"],"Chromosome":"11","Position":"48324920-48328471","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4C46","Gene synonym":[],"Ensembl":"ENSG00000185926","Gene description":"Olfactory receptor family 4 subfamily C member 46","Uniprot":["A6NHA9"],"Chromosome":"11","Position":"54603069-54603998","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4C5","Gene synonym":["OR4C5P","OR4C5Q"],"Ensembl":"ENSG00000176540","Gene description":"Olfactory receptor family 4 subfamily C member 5","Uniprot":["Q8NGB2"],"Chromosome":"11","Position":"48365485-48366465","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049516"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049516":"AB_2680800"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4C6","Gene synonym":[],"Ensembl":"ENSG00000181903","Gene description":"Olfactory receptor family 4 subfamily C member 6","Uniprot":["Q8NH72"],"Chromosome":"11","Position":"55662201-55666195","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"2.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4D1","Gene synonym":["OR4D3","TPCR16"],"Ensembl":"ENSG00000141194","Gene description":"Olfactory receptor family 4 subfamily D member 1","Uniprot":["Q15615"],"Chromosome":"17","Position":"58148449-58159555","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"NK-cells":"7.5","T-cells":"2.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4D10","Gene synonym":["OR4D10P","OST711"],"Ensembl":"ENSG00000254466","Gene description":"Olfactory receptor family 4 subfamily D member 10","Uniprot":["Q8NGI6"],"Chromosome":"11","Position":"59473315-59479361","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"thyroid cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-4"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4D11","Gene synonym":["OR4D11P"],"Ensembl":"ENSG00000176200","Gene description":"Olfactory receptor family 4 subfamily D member 11","Uniprot":["Q8NGI4"],"Chromosome":"11","Position":"59503576-59504511","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4D2","Gene synonym":[],"Ensembl":"ENSG00000255713","Gene description":"Olfactory receptor family 4 subfamily D member 2","Uniprot":["P58180"],"Chromosome":"17","Position":"58166982-58171411","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4D5","Gene synonym":[],"Ensembl":"ENSG00000171014","Gene description":"Olfactory receptor family 4 subfamily D member 5","Uniprot":["Q8NGN0"],"Chromosome":"11","Position":"123939543-123940637","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045005"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045005":"AB_10959302"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4D6","Gene synonym":[],"Ensembl":"ENSG00000166884","Gene description":"Olfactory receptor family 4 subfamily D member 6","Uniprot":["Q8NGJ1"],"Chromosome":"11","Position":"59456938-59457991","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4D9","Gene synonym":[],"Ensembl":"ENSG00000172742","Gene description":"Olfactory receptor family 4 subfamily D member 9","Uniprot":["Q8NGE8"],"Chromosome":"11","Position":"59511368-59520703","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"4.4","Erythroid cells":"3.5","Horizontal cells":"2.6","Langerhans cells":"2.6","NK-cells":"3.6","Rod photoreceptor cells":"4.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"2.0"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4E1","Gene synonym":["OR4E1P"],"Ensembl":"ENSG00000276240","Gene description":"Olfactory receptor family 4 subfamily E member 1","Uniprot":["P0C645"],"Chromosome":"14","Position":"21667940-21673818","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4E2","Gene synonym":[],"Ensembl":"ENSG00000221977","Gene description":"Olfactory receptor family 4 subfamily E member 2","Uniprot":["Q8NGC2"],"Chromosome":"14","Position":"21653835-21667642","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"Bone cancer":"4.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4F15","Gene synonym":[],"Ensembl":"ENSG00000182854","Gene description":"Olfactory receptor family 4 subfamily F member 15","Uniprot":["Q8NGB8"],"Chromosome":"15","Position":"101812202-101820197","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4F16","Gene synonym":[],"Ensembl":"ENSG00000284662","Gene description":"Olfactory receptor family 4 subfamily F member 16","Uniprot":["Q6IEY1"],"Chromosome":"1","Position":"685679-686673","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047705"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047705":"AB_2680125"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4F17","Gene synonym":["OR4F11P","OR4F18","OR4F19"],"Ensembl":"ENSG00000176695","Gene description":"Olfactory receptor family 4 subfamily F member 17","Uniprot":["Q8NGA8"],"Chromosome":"19","Position":"107104-117102","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4F21","Gene synonym":["OR4F21P"],"Ensembl":"ENSG00000176269","Gene description":"Olfactory receptor family 4 subfamily F member 21","Uniprot":["O95013"],"Chromosome":"8","Position":"166086-167024","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047705"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047705":"AB_2680125"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4F29","Gene synonym":[],"Ensembl":"ENSG00000284733","Gene description":"Olfactory receptor family 4 subfamily F member 29","Uniprot":["Q6IEY1"],"Chromosome":"1","Position":"450740-451678","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047705"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047705":"AB_2680125"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4F3","Gene synonym":[],"Ensembl":"ENSG00000230178","Gene description":"Olfactory receptor family 4 subfamily F member 3","Uniprot":["Q6IEY1"],"Chromosome":"5","Position":"181367268-181368262","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047705"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047705":"AB_2680125"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4F4","Gene synonym":["OR4F18"],"Ensembl":"ENSG00000177693","Gene description":"Olfactory receptor family 4 subfamily F member 4","Uniprot":["Q96R69"],"Chromosome":"15","Position":"101922042-101923113","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4F5","Gene synonym":[],"Ensembl":"ENSG00000186092","Gene description":"Olfactory receptor family 4 subfamily F member 5","Uniprot":["Q8NH21"],"Chromosome":"1","Position":"65419-71585","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4F6","Gene synonym":["OR4F12"],"Ensembl":"ENSG00000184140","Gene description":"Olfactory receptor family 4 subfamily F member 6","Uniprot":["Q8NGB9"],"Chromosome":"15","Position":"101803509-101806887","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4K1","Gene synonym":[],"Ensembl":"ENSG00000155249","Gene description":"Olfactory receptor family 4 subfamily K member 1","Uniprot":["Q8NGD4"],"Chromosome":"14","Position":"19930917-19936757","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028877"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA028877":"AB_10600923"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4K13","Gene synonym":[],"Ensembl":"ENSG00000176253","Gene description":"Olfactory receptor family 4 subfamily K member 13","Uniprot":["Q8NH42"],"Chromosome":"14","Position":"20029399-20036038","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4K14","Gene synonym":[],"Ensembl":"ENSG00000169484","Gene description":"Olfactory receptor family 4 subfamily K member 14","Uniprot":["Q8NGD5"],"Chromosome":"14","Position":"20014143-20019307","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4K15","Gene synonym":["OR4K15Q"],"Ensembl":"ENSG00000169488","Gene description":"Olfactory receptor family 4 subfamily K member 15","Uniprot":["Q8NH41"],"Chromosome":"14","Position":"19975444-19976659","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055732"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055732":"AB_2682900"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4K17","Gene synonym":[],"Ensembl":"ENSG00000176230","Gene description":"Olfactory receptor family 4 subfamily K member 17","Uniprot":["Q8NGC6"],"Chromosome":"14","Position":"20110739-20122199","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"2.2","liver":"4.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"1.8","cerebral cortex":"1.0","white matter":"1.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4K2","Gene synonym":[],"Ensembl":"ENSG00000165762","Gene description":"Olfactory receptor family 4 subfamily K member 2","Uniprot":["Q8NGD2"],"Chromosome":"14","Position":"19875142-19883932","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4K5","Gene synonym":[],"Ensembl":"ENSG00000176281","Gene description":"Olfactory receptor family 4 subfamily K member 5","Uniprot":["Q8NGD3"],"Chromosome":"14","Position":"19920582-19921659","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4L1","Gene synonym":["OR4L2P"],"Ensembl":"ENSG00000176246","Gene description":"Olfactory receptor family 4 subfamily L member 1","Uniprot":["Q8NH43"],"Chromosome":"14","Position":"20060045-20060983","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4M1","Gene synonym":[],"Ensembl":"ENSG00000176299","Gene description":"Olfactory receptor family 4 subfamily M member 1","Uniprot":["Q8NGD0"],"Chromosome":"14","Position":"19773504-19783696","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"59.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058889"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058889":"AB_2683845"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4M2","Gene synonym":[],"Ensembl":"ENSG00000274102","Gene description":"Olfactory receptor family 4 subfamily M member 2","Uniprot":["Q8NGB6"],"Chromosome":"15","Position":"22070241-22083221","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"45","RNA single cell type specific nTPM":{"Early spermatids":"49.1","Late spermatids":"14.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058889"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058889":"AB_2683845"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4M2B","Gene synonym":[],"Ensembl":"ENSG00000182974","Gene description":"Olfactory receptor family 4 subfamily M member 2B","Uniprot":[],"Chromosome":"15","Position":"21637909-21638992","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058889"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058889":"AB_2683845"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4N2","Gene synonym":[],"Ensembl":"ENSG00000176294","Gene description":"Olfactory receptor family 4 subfamily N member 2","Uniprot":["Q8NGD1"],"Chromosome":"14","Position":"19719015-19830253","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"testis":"3.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"18.7","Late spermatids":"6.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4N4","Gene synonym":[],"Ensembl":"ENSG00000183706","Gene description":"Olfactory receptor family 4 subfamily N member 4","Uniprot":["Q8N0Y3"],"Chromosome":"15","Position":"22094522-22095472","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"81","RNA tissue specific nTPM":{"testis":"8.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057442"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA057442":"AB_2683442"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4N4C","Gene synonym":[],"Ensembl":"ENSG00000279408","Gene description":"Olfactory receptor family 4 subfamily N member 4C","Uniprot":[],"Chromosome":"15","Position":"21651844-21652968","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"testis":"1.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057442"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA057442":"AB_2683442"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4N5","Gene synonym":[],"Ensembl":"ENSG00000184394","Gene description":"Olfactory receptor family 4 subfamily N member 5","Uniprot":["Q8IXE1"],"Chromosome":"14","Position":"20138820-20145471","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4P4","Gene synonym":["OR4P3P"],"Ensembl":"ENSG00000181927","Gene description":"Olfactory receptor family 4 subfamily P member 4","Uniprot":["Q8NGL7"],"Chromosome":"11","Position":"55635113-55640309","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059458"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059458":"AB_2684027"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4Q3","Gene synonym":["C14orf13","OR4Q4"],"Ensembl":"ENSG00000182652","Gene description":"Olfactory receptor family 4 subfamily Q member 3","Uniprot":[],"Chromosome":"14","Position":"19743571-19749469","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049924"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049924":"AB_2680955"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4S1","Gene synonym":[],"Ensembl":"ENSG00000176555","Gene description":"Olfactory receptor family 4 subfamily S member 1","Uniprot":["Q8NGB4"],"Chromosome":"11","Position":"48306223-48307152","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4S2","Gene synonym":["OR4S2P","OST725"],"Ensembl":"ENSG00000174982","Gene description":"Olfactory receptor family 4 subfamily S member 2","Uniprot":["Q8NH73"],"Chromosome":"11","Position":"55648327-55652854","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4X1","Gene synonym":[],"Ensembl":"ENSG00000176567","Gene description":"Olfactory receptor family 4 subfamily X member 1","Uniprot":["Q8NH49"],"Chromosome":"11","Position":"48263861-48264778","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR4X2","Gene synonym":[],"Ensembl":"ENSG00000172208","Gene description":"Olfactory receptor family 4 subfamily X member 2","Uniprot":["Q8NGF9"],"Chromosome":"11","Position":"48245056-48246080","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51A2","Gene synonym":[],"Ensembl":"ENSG00000205496","Gene description":"Olfactory receptor family 51 subfamily A member 2","Uniprot":["Q8NGJ7"],"Chromosome":"11","Position":"4954772-4955713","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51A4","Gene synonym":[],"Ensembl":"ENSG00000205497","Gene description":"Olfactory receptor family 51 subfamily A member 4","Uniprot":["Q8NGJ6"],"Chromosome":"11","Position":"4942831-4947605","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51A7","Gene synonym":[],"Ensembl":"ENSG00000176895","Gene description":"Olfactory receptor family 51 subfamily A member 7","Uniprot":["Q8NH64"],"Chromosome":"11","Position":"4903783-4909462","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"1.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061356"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA061356":"AB_2684488"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51B2","Gene synonym":["OR51B1P"],"Ensembl":"ENSG00000279012","Gene description":"Olfactory receptor family 51 subfamily B member 2","Uniprot":["Q9Y5P1"],"Chromosome":"11","Position":"5323359-5324297","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51B4","Gene synonym":[],"Ensembl":"ENSG00000183251","Gene description":"Olfactory receptor family 51 subfamily B member 4","Uniprot":["Q9Y5P0"],"Chromosome":"11","Position":"5301014-5301946","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Sertoli cells":"2.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51B5","Gene synonym":[],"Ensembl":"ENSG00000167355","Gene description":"Olfactory receptor family 51 subfamily B member 5","Uniprot":["Q9H339"],"Chromosome":"11","Position":"5303444-5505652","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"9.8","Excitatory neurons":"5.6","Late spermatids":"4.9","Microglial cells":"21.0","Oligodendrocyte precursor cells":"6.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"testis cancer":"1.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063124"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063124":"AB_2684943"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"}},{"Gene":"OR51B6","Gene synonym":[],"Ensembl":"ENSG00000176239","Gene description":"Olfactory receptor family 51 subfamily B member 6","Uniprot":["Q9H340"],"Chromosome":"11","Position":"5351508-5352446","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51C1P","Gene synonym":["OR51C2P","OR51C3P","OST734"],"Ensembl":"ENSG00000197674","Gene description":"Olfactory receptor family 51 subfamily C member 1 pseudogene","Uniprot":[],"Chromosome":"11","Position":"4690423-4697831","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Prostatic glandular cells":"3.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"65","RNA cancer specific FPKM":{"prostate cancer":"3.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51D1","Gene synonym":["OR51D1Q"],"Ensembl":"ENSG00000197428","Gene description":"Olfactory receptor family 51 subfamily D member 1","Uniprot":["Q8NGF3"],"Chromosome":"11","Position":"4637477-4643060","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"2.2","Horizontal cells":"2.6","Prostatic glandular cells":"1.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061240"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA061240":"AB_2684457"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51E1","Gene synonym":["GPR136","GPR164","OR51E1P","OR52A3P"],"Ensembl":"ENSG00000180785","Gene description":"Olfactory receptor family 51 subfamily E member 1","Uniprot":["Q8TCB6"],"Chromosome":"11","Position":"4643420-4655488","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"5.7","placenta":"7.4","prostate":"6.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"36.5","Enteroendocrine cells":"42.4","Prostatic glandular cells":"112.5","Sertoli cells":"13.8","Smooth muscle cells":"23.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"21","RNA cancer specific FPKM":{"prostate cancer":"34.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"colorectal cancer":"2.1","lung cancer":"2.1","prostate cancer":"7.5","thyroid cancer":"1.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019995","HPA051439"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB019995":"AB_10283600","HPA051439":"AB_2681487"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"}},{"Gene":"OR51E2","Gene synonym":["PSGR"],"Ensembl":"ENSG00000167332","Gene description":"Olfactory receptor family 51 subfamily E member 2","Uniprot":["Q9H255"],"Chromosome":"11","Position":"4680171-4697854","Protein class":["Cancer-related genes","G-protein coupled receptors","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"9.6","prostate":"28.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Enteroendocrine cells":"46.7","Prostatic glandular cells":"119.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"274","RNA cancer specific FPKM":{"prostate cancer":"217.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lung cancer":"7.0"},"RNA tissue cell type enrichment":["Adipose visceral - Smooth muscle cells","Heart muscle - Smooth muscle cells","Skeletal muscle - Smooth muscle cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"}},{"Gene":"OR51F1","Gene synonym":["OR51F1P"],"Ensembl":"ENSG00000280021","Gene description":"Olfactory receptor family 51 subfamily F member 1","Uniprot":["A6NGY5"],"Chromosome":"11","Position":"4768979-4769938","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51F2","Gene synonym":[],"Ensembl":"ENSG00000176925","Gene description":"Olfactory receptor family 51 subfamily F member 2","Uniprot":["Q8NH61"],"Chromosome":"11","Position":"4821321-4822456","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51G1","Gene synonym":["OR51G3P"],"Ensembl":"ENSG00000278870","Gene description":"Olfactory receptor family 51 subfamily G member 1","Uniprot":["Q8NGK1"],"Chromosome":"11","Position":"4923374-4924339","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51G2","Gene synonym":[],"Ensembl":"ENSG00000176893","Gene description":"Olfactory receptor family 51 subfamily G member 2","Uniprot":["Q8NGK0"],"Chromosome":"11","Position":"4912588-4919350","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51I1","Gene synonym":[],"Ensembl":"ENSG00000167359","Gene description":"Olfactory receptor family 51 subfamily I member 1","Uniprot":["Q9H343"],"Chromosome":"11","Position":"5440570-5441514","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"1.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"9","RNA pig brain regional specific nTPM":{"olfactory bulb":"3.0"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51I2","Gene synonym":[],"Ensembl":"ENSG00000187918","Gene description":"Olfactory receptor family 51 subfamily I member 2","Uniprot":["Q9H344"],"Chromosome":"11","Position":"5449323-5456518","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51L1","Gene synonym":[],"Ensembl":"ENSG00000176798","Gene description":"Olfactory receptor family 51 subfamily L member 1","Uniprot":["Q8NGJ5"],"Chromosome":"11","Position":"4994851-5005536","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"1.5","Late spermatids":"2.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51M1","Gene synonym":[],"Ensembl":"ENSG00000184698","Gene description":"Olfactory receptor family 51 subfamily M member 1","Uniprot":["Q9H341"],"Chromosome":"11","Position":"5383812-5393263","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7","granulocytes":"1.8","Langerhans cells":"2.6","Rod photoreceptor cells":"1.2","Sertoli cells":"2.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056773"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056773":"AB_2683233"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51Q1","Gene synonym":[],"Ensembl":"ENSG00000167360","Gene description":"Olfactory receptor family 51 subfamily Q member 1","Uniprot":["Q8NH59"],"Chromosome":"11","Position":"5422111-5423206","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044998"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044998":"AB_10794780"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51S1","Gene synonym":[],"Ensembl":"ENSG00000176922","Gene description":"Olfactory receptor family 51 subfamily S member 1","Uniprot":["Q8NGJ8"],"Chromosome":"11","Position":"4847489-4849238","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51T1","Gene synonym":[],"Ensembl":"ENSG00000176900","Gene description":"Olfactory receptor family 51 subfamily T member 1","Uniprot":["Q8NGJ9"],"Chromosome":"11","Position":"4881819-4882883","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046877"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046877":"AB_2679853"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR51V1","Gene synonym":["OR51A12"],"Ensembl":"ENSG00000176742","Gene description":"Olfactory receptor family 51 subfamily V member 1","Uniprot":[],"Chromosome":"11","Position":"5199735-5200682","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52A1","Gene synonym":["HPFH1OR"],"Ensembl":"ENSG00000182070","Gene description":"Olfactory receptor family 52 subfamily A member 1","Uniprot":["Q9UKL2"],"Chromosome":"11","Position":"5146824-5154757","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Smooth muscle cells":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52A5","Gene synonym":[],"Ensembl":"ENSG00000171944","Gene description":"Olfactory receptor family 52 subfamily A member 5","Uniprot":["Q9H2C5"],"Chromosome":"11","Position":"5128776-5138356","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 47: Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52B2","Gene synonym":[],"Ensembl":"ENSG00000255307","Gene description":"Olfactory receptor family 52 subfamily B member 2","Uniprot":["Q96RD2"],"Chromosome":"11","Position":"6169330-6170408","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52B4","Gene synonym":[],"Ensembl":"ENSG00000221996","Gene description":"Olfactory receptor family 52 subfamily B member 4","Uniprot":["Q8NGK2"],"Chromosome":"11","Position":"4367263-4368386","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52B6","Gene synonym":[],"Ensembl":"ENSG00000187747","Gene description":"Olfactory receptor family 52 subfamily B member 6","Uniprot":["Q8NGF0"],"Chromosome":"11","Position":"5580877-5581884","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52D1","Gene synonym":[],"Ensembl":"ENSG00000181609","Gene description":"Olfactory receptor family 52 subfamily D member 1","Uniprot":["Q9H346"],"Chromosome":"11","Position":"5488685-5489749","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"testis":"1.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"13","RNA pig brain regional specific nTPM":{"olfactory bulb":"3.1"},"Antibody":["HPA046965"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046965":"AB_2679878"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52E2","Gene synonym":[],"Ensembl":"ENSG00000176787","Gene description":"Olfactory receptor family 52 subfamily E member 2","Uniprot":["Q8NGJ4"],"Chromosome":"11","Position":"5058650-5059627","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045748"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045748":"AB_10959665"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52E4","Gene synonym":[],"Ensembl":"ENSG00000180974","Gene description":"Olfactory receptor family 52 subfamily E member 4","Uniprot":["Q8NGH9"],"Chromosome":"11","Position":"5880629-5887079","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52E5","Gene synonym":[],"Ensembl":"ENSG00000277932","Gene description":"Olfactory receptor family 52 subfamily E member 5","Uniprot":["Q8NH55"],"Chromosome":"11","Position":"5893208-5902730","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52E6","Gene synonym":[],"Ensembl":"ENSG00000205409","Gene description":"Olfactory receptor family 52 subfamily E member 6","Uniprot":["Q96RD3"],"Chromosome":"11","Position":"5840928-5841952","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52E8","Gene synonym":[],"Ensembl":"ENSG00000183269","Gene description":"Olfactory receptor family 52 subfamily E member 8","Uniprot":["Q6IFG1"],"Chromosome":"11","Position":"5856674-5857734","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52H1","Gene synonym":[],"Ensembl":"ENSG00000181616","Gene description":"Olfactory receptor family 52 subfamily H member 1","Uniprot":["Q8NGJ2"],"Chromosome":"11","Position":"5544489-5548533","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52I1","Gene synonym":[],"Ensembl":"ENSG00000232268","Gene description":"Olfactory receptor family 52 subfamily I member 1","Uniprot":["Q8NGK6"],"Chromosome":"11","Position":"4593614-4596574","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"2.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.7","Cone photoreceptor cells":"1.7","Rod photoreceptor cells":"1.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52I2","Gene synonym":[],"Ensembl":"ENSG00000226288","Gene description":"Olfactory receptor family 52 subfamily I member 2","Uniprot":["Q8NH67"],"Chromosome":"11","Position":"4581743-4593340","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049343"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049343":"AB_2680721"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52J3","Gene synonym":[],"Ensembl":"ENSG00000205495","Gene description":"Olfactory receptor family 52 subfamily J member 3","Uniprot":["Q8NH60"],"Chromosome":"11","Position":"5046526-5047461","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52K1","Gene synonym":[],"Ensembl":"ENSG00000196778","Gene description":"Olfactory receptor family 52 subfamily K member 1","Uniprot":["Q8NGK4"],"Chromosome":"11","Position":"4482646-4493497","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52K2","Gene synonym":[],"Ensembl":"ENSG00000181963","Gene description":"Olfactory receptor family 52 subfamily K member 2","Uniprot":["Q8NGK3"],"Chromosome":"11","Position":"4449295-4450361","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"3.3"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"granulocytes":"3.3"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52L1","Gene synonym":[],"Ensembl":"ENSG00000183313","Gene description":"Olfactory receptor family 52 subfamily L member 1","Uniprot":["Q8NGH7"],"Chromosome":"11","Position":"5985892-5986985","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52M1","Gene synonym":["OR52M1P"],"Ensembl":"ENSG00000197790","Gene description":"Olfactory receptor family 52 subfamily M member 1","Uniprot":["Q8NGK5"],"Chromosome":"11","Position":"4545191-4546144","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52N1","Gene synonym":[],"Ensembl":"ENSG00000181001","Gene description":"Olfactory receptor family 52 subfamily N member 1","Uniprot":["Q8NH53"],"Chromosome":"11","Position":"5786471-5791265","Protein class":["Cancer-related genes","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054028"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054028":"AB_2682348"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52N2","Gene synonym":[],"Ensembl":"ENSG00000180988","Gene description":"Olfactory receptor family 52 subfamily N member 2","Uniprot":["Q8NGI0"],"Chromosome":"11","Position":"5820314-5821348","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"4.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"40","RNA blood cell specific nTPM":{"basophil":"4.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"40","RNA blood lineage specific nTPM":{"granulocytes":"4.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52N4","Gene synonym":[],"Ensembl":"ENSG00000181074","Gene description":"Olfactory receptor family 52 subfamily N member 4","Uniprot":["Q8NGI2"],"Chromosome":"11","Position":"5754243-5755905","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"2.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"}},{"Gene":"OR52N5","Gene synonym":["OR52N5Q"],"Ensembl":"ENSG00000181009","Gene description":"Olfactory receptor family 52 subfamily N member 5","Uniprot":["Q8NH56"],"Chromosome":"11","Position":"5776165-5783355","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"1.5","Basal prostatic cells":"2.8","Endothelial cells":"1.3","Mucus glandular cells":"1.4","Spermatogonia":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52R1","Gene synonym":[],"Ensembl":"ENSG00000279270","Gene description":"Olfactory receptor family 52 subfamily R member 1","Uniprot":["Q8NGF1"],"Chromosome":"11","Position":"4803433-4804380","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR52W1","Gene synonym":["OR52W1P"],"Ensembl":"ENSG00000175485","Gene description":"Olfactory receptor family 52 subfamily W member 1","Uniprot":["Q6IF63"],"Chromosome":"11","Position":"6199146-6200259","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR56A1","Gene synonym":[],"Ensembl":"ENSG00000180934","Gene description":"Olfactory receptor family 56 subfamily A member 1","Uniprot":[],"Chromosome":"11","Position":"6019336-6034338","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR56A3","Gene synonym":["OR56A3P","OR56A6"],"Ensembl":"ENSG00000184478","Gene description":"Olfactory receptor family 56 subfamily A member 3","Uniprot":["Q8NH54"],"Chromosome":"11","Position":"5938751-5951347","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"2.8","Spermatocytes":"2.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Esophageal cancer":"1.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR56A4","Gene synonym":[],"Ensembl":"ENSG00000183389","Gene description":"Olfactory receptor family 56 subfamily A member 4","Uniprot":["Q8NGH8"],"Chromosome":"11","Position":"5999445-6006946","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"6.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR56A5","Gene synonym":["OR56A5P"],"Ensembl":"ENSG00000188691","Gene description":"Olfactory receptor family 56 subfamily A member 5","Uniprot":["P0C7T3"],"Chromosome":"11","Position":"5967177-5968494","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR56B1","Gene synonym":["OR56B1P"],"Ensembl":"ENSG00000181023","Gene description":"Olfactory receptor family 56 subfamily B member 1","Uniprot":["Q8NGI3"],"Chromosome":"11","Position":"5736448-5738523","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045043"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045043":"AB_10794296"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR56B2P","Gene synonym":["OR56B2"],"Ensembl":"ENSG00000181017","Gene description":"Olfactory receptor family 56 subfamily B member 2 pseudogene","Uniprot":[],"Chromosome":"11","Position":"5761153-5767465","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR56B4","Gene synonym":[],"Ensembl":"ENSG00000180919","Gene description":"Olfactory receptor family 56 subfamily B member 4","Uniprot":["Q8NH76"],"Chromosome":"11","Position":"6107684-6108835","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"}},{"Gene":"OR5A1","Gene synonym":["OR5A1P","OST181"],"Ensembl":"ENSG00000172320","Gene description":"Olfactory receptor family 5 subfamily A member 1","Uniprot":["Q8NGJ0"],"Chromosome":"11","Position":"59436469-59451380","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.8"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 47: Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5A2","Gene synonym":[],"Ensembl":"ENSG00000172324","Gene description":"Olfactory receptor family 5 subfamily A member 2","Uniprot":["Q8NGI9"],"Chromosome":"11","Position":"59416969-59426413","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"1.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047135","HPA049575"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047135":"AB_2679948","HPA049575":"AB_2680820"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5AC2","Gene synonym":["HSA1"],"Ensembl":"ENSG00000196578","Gene description":"Olfactory receptor family 5 subfamily AC member 2","Uniprot":["Q9NZP5"],"Chromosome":"3","Position":"98087173-98088102","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Early spermatids":"1.9","Late spermatids":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5AK2","Gene synonym":[],"Ensembl":"ENSG00000181273","Gene description":"Olfactory receptor family 5 subfamily AK member 2","Uniprot":["Q8NH90"],"Chromosome":"11","Position":"56988872-56989867","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"5.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"white matter":"1.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5AN1","Gene synonym":[],"Ensembl":"ENSG00000176495","Gene description":"Olfactory receptor family 5 subfamily AN member 1","Uniprot":["Q8NGI8"],"Chromosome":"11","Position":"59358895-59371714","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5AP2","Gene synonym":[],"Ensembl":"ENSG00000172464","Gene description":"Olfactory receptor family 5 subfamily AP member 2","Uniprot":["Q8NGF4"],"Chromosome":"11","Position":"56641466-56642471","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5AR1","Gene synonym":[],"Ensembl":"ENSG00000172459","Gene description":"Olfactory receptor family 5 subfamily AR member 1","Uniprot":["Q8NGP9"],"Chromosome":"11","Position":"56663662-56664687","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5AS1","Gene synonym":[],"Ensembl":"ENSG00000181785","Gene description":"Olfactory receptor family 5 subfamily AS member 1","Uniprot":["Q8N127"],"Chromosome":"11","Position":"56027654-56038191","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5AU1","Gene synonym":[],"Ensembl":"ENSG00000169327","Gene description":"Olfactory receptor family 5 subfamily AU member 1","Uniprot":["Q8NGC0"],"Chromosome":"14","Position":"21148370-21159060","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"1.2","Glandular and luminal cells":"3.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5B12","Gene synonym":["OR5B12P","OR5B16","OST743"],"Ensembl":"ENSG00000172362","Gene description":"Olfactory receptor family 5 subfamily B member 12","Uniprot":["Q96R08"],"Chromosome":"11","Position":"58439077-58442758","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5B17","Gene synonym":["OR5B20P"],"Ensembl":"ENSG00000197786","Gene description":"Olfactory receptor family 5 subfamily B member 17","Uniprot":["Q8NGF7"],"Chromosome":"11","Position":"58358124-58359069","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5B2","Gene synonym":["OST073"],"Ensembl":"ENSG00000172365","Gene description":"Olfactory receptor family 5 subfamily B member 2","Uniprot":["Q96R09"],"Chromosome":"11","Position":"58421238-58428121","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5B21","Gene synonym":[],"Ensembl":"ENSG00000198283","Gene description":"Olfactory receptor family 5 subfamily B member 21","Uniprot":["A6NL26"],"Chromosome":"11","Position":"58507175-58508105","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5B3","Gene synonym":["OR5B13","OST129"],"Ensembl":"ENSG00000172769","Gene description":"Olfactory receptor family 5 subfamily B member 3","Uniprot":["Q8NH48"],"Chromosome":"11","Position":"58402464-58406874","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5BS1P","Gene synonym":["OR5BS1"],"Ensembl":"ENSG00000198678","Gene description":"Olfactory receptor family 5 subfamily BS member 1 pseudogene","Uniprot":[],"Chromosome":"12","Position":"48559882-48562956","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5C1","Gene synonym":["hRPK-465_F_21","OR5C2P","OR9-F"],"Ensembl":"ENSG00000148215","Gene description":"Olfactory receptor family 5 subfamily C member 1","Uniprot":["Q8NGR4"],"Chromosome":"9","Position":"122788933-122789895","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5D13","Gene synonym":[],"Ensembl":"ENSG00000279761","Gene description":"Olfactory receptor family 5 subfamily D member 13","Uniprot":["Q8NGL4"],"Chromosome":"11","Position":"55773438-55774382","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5D14","Gene synonym":[],"Ensembl":"ENSG00000186113","Gene description":"Olfactory receptor family 5 subfamily D member 14","Uniprot":["Q8NGL3"],"Chromosome":"11","Position":"55795556-55796500","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5D16","Gene synonym":[],"Ensembl":"ENSG00000205029","Gene description":"Olfactory receptor family 5 subfamily D member 16","Uniprot":["Q8NGK9"],"Chromosome":"11","Position":"55838752-55839738","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046711"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046711":"AB_2679766"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5D18","Gene synonym":[],"Ensembl":"ENSG00000186119","Gene description":"Olfactory receptor family 5 subfamily D member 18","Uniprot":["Q8NGL1"],"Chromosome":"11","Position":"55819607-55820597","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5D3P","Gene synonym":["OR11-8b","OR11-8c","OR5D3","OR5D4"],"Ensembl":"ENSG00000186886","Gene description":"Olfactory receptor family 5 subfamily D member 3 pseudogene","Uniprot":[],"Chromosome":"11","Position":"55723776-55729621","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5F1","Gene synonym":["OR11-10"],"Ensembl":"ENSG00000149133","Gene description":"Olfactory receptor family 5 subfamily F member 1","Uniprot":["O95221"],"Chromosome":"11","Position":"55993681-55994625","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059360"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059360":"AB_2683990"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5H1","Gene synonym":["HSHTPCRX14","HTPCRX14"],"Ensembl":"ENSG00000231192","Gene description":"Olfactory receptor family 5 subfamily H member 1","Uniprot":["A6NKK0"],"Chromosome":"3","Position":"98130721-98138548","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5H14","Gene synonym":[],"Ensembl":"ENSG00000236032","Gene description":"Olfactory receptor family 5 subfamily H member 14","Uniprot":["A6NHG9"],"Chromosome":"3","Position":"98147479-98156614","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"2.0","Langerhans cells":"3.5","Melanocytes":"1.7","monocytes":"1.7","Skeletal myocytes":"2.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5H15","Gene synonym":[],"Ensembl":"ENSG00000233412","Gene description":"Olfactory receptor family 5 subfamily H member 15","Uniprot":["A6NDH6"],"Chromosome":"3","Position":"98166696-98169774","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5H2","Gene synonym":[],"Ensembl":"ENSG00000197938","Gene description":"Olfactory receptor family 5 subfamily H member 2","Uniprot":["Q8NGV7"],"Chromosome":"3","Position":"98282888-98283832","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5H6","Gene synonym":[],"Ensembl":"ENSG00000230301","Gene description":"Olfactory receptor family 5 subfamily H member 6","Uniprot":["Q8NGV6"],"Chromosome":"3","Position":"98263252-98265356","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"29","RNA single cell type specific nTPM":{"Early spermatids":"3.1","Late spermatids":"2.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5I1","Gene synonym":["HSOlf1","OLF1"],"Ensembl":"ENSG00000167825","Gene description":"Olfactory receptor family 5 subfamily I member 1","Uniprot":["Q13606"],"Chromosome":"11","Position":"55935456-55936400","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5J2","Gene synonym":[],"Ensembl":"ENSG00000174957","Gene description":"Olfactory receptor family 5 subfamily J member 2","Uniprot":["Q8NH18"],"Chromosome":"11","Position":"56176618-56177556","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059466"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059466":"AB_2684029"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5K1","Gene synonym":["HSHTPCRX10","HTPCRX10"],"Ensembl":"ENSG00000232382","Gene description":"Olfactory receptor family 5 subfamily K member 1","Uniprot":["Q8NHB7"],"Chromosome":"3","Position":"98463201-98472924","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5K2","Gene synonym":[],"Ensembl":"ENSG00000231861","Gene description":"Olfactory receptor family 5 subfamily K member 2","Uniprot":["Q8NHB8"],"Chromosome":"3","Position":"98497604-98498663","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"}},{"Gene":"OR5K3","Gene synonym":[],"Ensembl":"ENSG00000206536","Gene description":"Olfactory receptor family 5 subfamily K member 3","Uniprot":["A6NET4"],"Chromosome":"3","Position":"98390666-98391631","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5K4","Gene synonym":[],"Ensembl":"ENSG00000196098","Gene description":"Olfactory receptor family 5 subfamily K member 4","Uniprot":["A6NMS3"],"Chromosome":"3","Position":"98353854-98354819","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5L1","Gene synonym":["OST262"],"Ensembl":"ENSG00000279395","Gene description":"Olfactory receptor family 5 subfamily L member 1","Uniprot":["Q8NGL2"],"Chromosome":"11","Position":"55811367-55812476","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047524"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047524":"AB_2680076"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5L2","Gene synonym":["HSHTPCRX16","HTPCRX16"],"Ensembl":"ENSG00000205030","Gene description":"Olfactory receptor family 5 subfamily L member 2","Uniprot":["Q8NGL0"],"Chromosome":"11","Position":"55827219-55828154","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047524"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047524":"AB_2680076"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5M1","Gene synonym":["OST050"],"Ensembl":"ENSG00000255012","Gene description":"Olfactory receptor family 5 subfamily M member 1","Uniprot":["Q8NGP8"],"Chromosome":"11","Position":"56609236-56614874","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5M10","Gene synonym":[],"Ensembl":"ENSG00000254834","Gene description":"Olfactory receptor family 5 subfamily M member 10","Uniprot":["Q6IEU7"],"Chromosome":"11","Position":"56576736-56577787","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5M11","Gene synonym":["OR11-199"],"Ensembl":"ENSG00000255223","Gene description":"Olfactory receptor family 5 subfamily M member 11","Uniprot":["Q96RB7"],"Chromosome":"11","Position":"56542262-56543281","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Late spermatids":"2.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"}},{"Gene":"OR5M3","Gene synonym":[],"Ensembl":"ENSG00000174937","Gene description":"Olfactory receptor family 5 subfamily M member 3","Uniprot":["Q8NGP4"],"Chromosome":"11","Position":"56469274-56473352","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5M8","Gene synonym":[],"Ensembl":"ENSG00000181371","Gene description":"Olfactory receptor family 5 subfamily M member 8","Uniprot":["Q8NGP6"],"Chromosome":"11","Position":"56490349-56491395","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5M9","Gene synonym":[],"Ensembl":"ENSG00000150269","Gene description":"Olfactory receptor family 5 subfamily M member 9","Uniprot":["Q8NGP3"],"Chromosome":"11","Position":"56462469-56463401","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5P2","Gene synonym":["JCG3"],"Ensembl":"ENSG00000183303","Gene description":"Olfactory receptor family 5 subfamily P member 2","Uniprot":["Q8WZ92"],"Chromosome":"11","Position":"7795905-7796973","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"25.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5P3","Gene synonym":["JCG1"],"Ensembl":"ENSG00000182334","Gene description":"Olfactory receptor family 5 subfamily P member 3","Uniprot":["Q8WZ94"],"Chromosome":"11","Position":"7824818-7830840","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"14.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060787"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060787":"AB_2684364"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"}},{"Gene":"OR5T1","Gene synonym":["OR5T1P"],"Ensembl":"ENSG00000181698","Gene description":"Olfactory receptor family 5 subfamily T member 1","Uniprot":["Q8NG75"],"Chromosome":"11","Position":"56274154-56276819","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050952"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050952":"AB_2681287"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5T2","Gene synonym":[],"Ensembl":"ENSG00000181718","Gene description":"Olfactory receptor family 5 subfamily T member 2","Uniprot":["Q8NGG2"],"Chromosome":"11","Position":"56231282-56234255","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5T3","Gene synonym":["OR5T3Q"],"Ensembl":"ENSG00000172489","Gene description":"Olfactory receptor family 5 subfamily T member 3","Uniprot":[],"Chromosome":"11","Position":"56252254-56253222","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5V1","Gene synonym":["hs6M1-21"],"Ensembl":"ENSG00000243729","Gene description":"Olfactory receptor family 5 subfamily V member 1","Uniprot":["Q9UGF6"],"Chromosome":"6","Position":"29353749-29431967","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Early spermatids":"14.9","Late spermatids":"15.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"13","RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.3"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046707"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046707":"AB_2679763"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR5W2","Gene synonym":["OR5W2P","OR5W3P"],"Ensembl":"ENSG00000187612","Gene description":"Olfactory receptor family 5 subfamily W member 2","Uniprot":["Q8NH69"],"Chromosome":"11","Position":"55913650-55914582","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6A2","Gene synonym":["OR11-55","OR6A1","OR6A2P"],"Ensembl":"ENSG00000184933","Gene description":"Olfactory receptor family 6 subfamily A member 2","Uniprot":["O95222"],"Chromosome":"11","Position":"6791736-6799689","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"3.4","Early spermatids":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6B1","Gene synonym":["OR7-3"],"Ensembl":"ENSG00000221813","Gene description":"Olfactory receptor family 6 subfamily B member 1","Uniprot":["O95007"],"Chromosome":"7","Position":"144000320-144008793","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053164"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053164":"AB_2682065"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6B2","Gene synonym":["OR6B2P"],"Ensembl":"ENSG00000182083","Gene description":"Olfactory receptor family 6 subfamily B member 2","Uniprot":["Q6IFH4"],"Chromosome":"2","Position":"240028965-240030456","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047529"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA047529":"AB_2680077"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6B3","Gene synonym":["OR6B3P","OR6B3Q"],"Ensembl":"ENSG00000178586","Gene description":"Olfactory receptor family 6 subfamily B member 3","Uniprot":["Q8NGW1"],"Chromosome":"2","Position":"240045077-240047027","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"retina":"20.9"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047529"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA047529":"AB_2680077"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6C1","Gene synonym":["OST267"],"Ensembl":"ENSG00000205330","Gene description":"Olfactory receptor family 6 subfamily C member 1","Uniprot":["Q96RD1"],"Chromosome":"12","Position":"55314343-55322364","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6C2","Gene synonym":["OR6C67"],"Ensembl":"ENSG00000179695","Gene description":"Olfactory receptor family 6 subfamily C member 2","Uniprot":["Q9NZP2"],"Chromosome":"12","Position":"55444069-55453347","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6C3","Gene synonym":["OST709"],"Ensembl":"ENSG00000205329","Gene description":"Olfactory receptor family 6 subfamily C member 3","Uniprot":["Q9NZP0"],"Chromosome":"12","Position":"55330043-55332687","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6C4","Gene synonym":[],"Ensembl":"ENSG00000179626","Gene description":"Olfactory receptor family 6 subfamily C member 4","Uniprot":["Q8NGE1"],"Chromosome":"12","Position":"55549602-55555832","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Paneth cells":"1.2","Sertoli cells":"2.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6C6","Gene synonym":[],"Ensembl":"ENSG00000188324","Gene description":"Olfactory receptor family 6 subfamily C member 6","Uniprot":["A6NF89"],"Chromosome":"12","Position":"55293988-55296569","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051090"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Lipid droplets","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":["Lipid droplets","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA051090":"AB_2681341"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6C65","Gene synonym":[],"Ensembl":"ENSG00000205328","Gene description":"Olfactory receptor family 6 subfamily C member 65","Uniprot":["A6NJZ3"],"Chromosome":"12","Position":"55400430-55401505","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6C68","Gene synonym":[],"Ensembl":"ENSG00000205327","Gene description":"Olfactory receptor family 6 subfamily C member 68","Uniprot":["A6NDL8"],"Chromosome":"12","Position":"55492378-55493316","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6C70","Gene synonym":[],"Ensembl":"ENSG00000184954","Gene description":"Olfactory receptor family 6 subfamily C member 70","Uniprot":["A6NIJ9"],"Chromosome":"12","Position":"55469200-55470138","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1.3","Inhibitory neurons":"1.1","Oligodendrocyte precursor cells":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6C74","Gene synonym":[],"Ensembl":"ENSG00000197706","Gene description":"Olfactory receptor family 6 subfamily C member 74","Uniprot":["A6NCV1"],"Chromosome":"12","Position":"55247198-55248302","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6C75","Gene synonym":[],"Ensembl":"ENSG00000187857","Gene description":"Olfactory receptor family 6 subfamily C member 75","Uniprot":["A6NL08"],"Chromosome":"12","Position":"55362975-55369279","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6C76","Gene synonym":[],"Ensembl":"ENSG00000185821","Gene description":"Olfactory receptor family 6 subfamily C member 76","Uniprot":["A6NM76"],"Chromosome":"12","Position":"55426254-55427192","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6F1","Gene synonym":["OST731"],"Ensembl":"ENSG00000169214","Gene description":"Olfactory receptor family 6 subfamily F member 1","Uniprot":["Q8NGZ6"],"Chromosome":"1","Position":"247711436-247716646","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"1.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"40","RNA single cell type specific nTPM":{"Early spermatids":"16.8","Late spermatids":"5.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6J1","Gene synonym":["OR6J1P","OR6J2"],"Ensembl":"ENSG00000255804","Gene description":"Olfactory receptor family 6 subfamily J member 1","Uniprot":["Q8NGC5"],"Chromosome":"14","Position":"22630929-22644352","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6K2","Gene synonym":[],"Ensembl":"ENSG00000196171","Gene description":"Olfactory receptor family 6 subfamily K member 2","Uniprot":["Q8NGY2"],"Chromosome":"1","Position":"158699678-158700652","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6K3","Gene synonym":[],"Ensembl":"ENSG00000203757","Gene description":"Olfactory receptor family 6 subfamily K member 3","Uniprot":["Q8NGY3"],"Chromosome":"1","Position":"158716327-158720720","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"1.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"21","RNA blood cell specific nTPM":{"basophil":"8.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"granulocytes":"8.1"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055949"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055949":"AB_2682982"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6K6","Gene synonym":[],"Ensembl":"ENSG00000180433","Gene description":"Olfactory receptor family 6 subfamily K member 6","Uniprot":["Q8NGW6"],"Chromosome":"1","Position":"158754720-158755891","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"38","RNA blood cell specific nTPM":{"basophil":"3.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"38","RNA blood lineage specific nTPM":{"granulocytes":"3.7"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6M1","Gene synonym":[],"Ensembl":"ENSG00000196099","Gene description":"Olfactory receptor family 6 subfamily M member 1","Uniprot":["Q8NGM8"],"Chromosome":"11","Position":"123805335-123806387","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048674"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048674":"AB_2680489"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6N1","Gene synonym":[],"Ensembl":"ENSG00000197403","Gene description":"Olfactory receptor family 6 subfamily N member 1","Uniprot":["Q8NGY5"],"Chromosome":"1","Position":"158747814-158772195","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"5.4","Late spermatids":"1.5","Macrophages":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"25","RNA blood cell specific nTPM":{"basophil":"5.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"52","RNA blood lineage specific nTPM":{"granulocytes":"5.1"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6N2","Gene synonym":[],"Ensembl":"ENSG00000188340","Gene description":"Olfactory receptor family 6 subfamily N member 2","Uniprot":["Q8NGY6"],"Chromosome":"1","Position":"158774222-158781204","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"bone marrow":"1.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"basophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"1.0"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056637"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056637":"AB_2683198"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6P1","Gene synonym":[],"Ensembl":"ENSG00000186440","Gene description":"Olfactory receptor family 6 subfamily P member 1","Uniprot":["Q8NGX9"],"Chromosome":"1","Position":"158560606-158570580","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047466"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047466":"AB_10963091"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6Q1","Gene synonym":[],"Ensembl":"ENSG00000279051","Gene description":"Olfactory receptor family 6 subfamily Q member 1","Uniprot":["Q8NGQ2"],"Chromosome":"11","Position":"58030930-58031931","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6S1","Gene synonym":["OR6S1Q"],"Ensembl":"ENSG00000181803","Gene description":"Olfactory receptor family 6 subfamily S member 1","Uniprot":["Q8NH40"],"Chromosome":"14","Position":"20640696-20641691","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6T1","Gene synonym":[],"Ensembl":"ENSG00000181499","Gene description":"Olfactory receptor family 6 subfamily T member 1","Uniprot":["Q8NGN1"],"Chromosome":"11","Position":"123942785-123943873","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060893"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060893":"AB_2684380"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-4"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6V1","Gene synonym":["GPR138"],"Ensembl":"ENSG00000225781","Gene description":"Olfactory receptor family 6 subfamily V member 1","Uniprot":["Q8N148"],"Chromosome":"7","Position":"143052320-143053347","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"brain":"2.8"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6X1","Gene synonym":[],"Ensembl":"ENSG00000221931","Gene description":"Olfactory receptor family 6 subfamily X member 1","Uniprot":["Q8NH79"],"Chromosome":"11","Position":"123753488-123754545","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR6Y1","Gene synonym":["OR6Y2"],"Ensembl":"ENSG00000197532","Gene description":"Olfactory receptor family 6 subfamily Y member 1","Uniprot":["Q8NGX8"],"Chromosome":"1","Position":"158544550-158554405","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.1","retina":"1.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR7A10","Gene synonym":[],"Ensembl":"ENSG00000127515","Gene description":"Olfactory receptor family 7 subfamily A member 10","Uniprot":["O76100"],"Chromosome":"19","Position":"14840466-14848922","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR7A17","Gene synonym":["HTPCRX19"],"Ensembl":"ENSG00000185385","Gene description":"Olfactory receptor family 7 subfamily A member 17","Uniprot":["O14581"],"Chromosome":"19","Position":"14878203-14886132","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"1.9","Melanocytes":"1.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 69: BICR 18 - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR7A5","Gene synonym":["HTPCR2"],"Ensembl":"ENSG00000188269","Gene description":"Olfactory receptor family 7 subfamily A member 5","Uniprot":["Q15622"],"Chromosome":"19","Position":"14826241-14835185","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.9","epididymis":"4.5","parathyroid gland":"7.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Melanocytes":"7.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"melanoma":"2.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate basal glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053823"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053823":"AB_2682274"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-3"}},{"Gene":"OR7C1","Gene synonym":["OR19-5","OR7C4"],"Ensembl":"ENSG00000127530","Gene description":"Olfactory receptor family 7 subfamily C member 1","Uniprot":["O76099"],"Chromosome":"19","Position":"14789260-14835376","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"6.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"15.6","Melanocytes":"8.7","Prostatic glandular cells":"5.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"melanoma":"1.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047127"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047127":"AB_2679944"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-4"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"}},{"Gene":"OR7C2","Gene synonym":["OR19-18","OR7C3"],"Ensembl":"ENSG00000127529","Gene description":"Olfactory receptor family 7 subfamily C member 2","Uniprot":["O60412"],"Chromosome":"19","Position":"14941489-14942448","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047295"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047295":"AB_2680013"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR7D2","Gene synonym":["FLJ38149","HTPCRH03","OR19-4"],"Ensembl":"ENSG00000188000","Gene description":"Olfactory receptor family 7 subfamily D member 2","Uniprot":["Q96RA2"],"Chromosome":"19","Position":"9178979-9188818","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"8.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-4"}},{"Gene":"OR7D4","Gene synonym":["hg105","OR19-B","OR7D4P"],"Ensembl":"ENSG00000174667","Gene description":"Olfactory receptor family 7 subfamily D member 4","Uniprot":["Q8NG98"],"Chromosome":"19","Position":"9210276-9219589","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"1.4"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR7E24","Gene synonym":["HSHT2","OR19-8","OR7E24P","OR7E24Q"],"Ensembl":"ENSG00000237521","Gene description":"Olfactory receptor family 7 subfamily E member 24","Uniprot":["Q6IFN5"],"Chromosome":"19","Position":"9247344-9252625","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"testis":"1.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Early spermatids":"15.8","Late spermatids":"5.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"testis cancer":"2.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR7G1","Gene synonym":["OR19-15","OR7G1P"],"Ensembl":"ENSG00000161807","Gene description":"Olfactory receptor family 7 subfamily G member 1","Uniprot":["Q8NGA0"],"Chromosome":"19","Position":"9114828-9115763","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR7G2","Gene synonym":["OST260"],"Ensembl":"ENSG00000170923","Gene description":"Olfactory receptor family 7 subfamily G member 2","Uniprot":["Q8NG99"],"Chromosome":"19","Position":"9100407-9107475","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Langerhans cells":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR7G3","Gene synonym":["OST085"],"Ensembl":"ENSG00000170920","Gene description":"Olfactory receptor family 7 subfamily G member 3","Uniprot":["Q8NG95"],"Chromosome":"19","Position":"9126012-9126950","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8A1","Gene synonym":["OST025"],"Ensembl":"ENSG00000196119","Gene description":"Olfactory receptor family 8 subfamily A member 1","Uniprot":["Q8NGG7"],"Chromosome":"11","Position":"124566660-124582942","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"4.3","Excitatory neurons":"1.1","Late spermatids":"4.0","Spermatocytes":"1.2","Spermatogonia":"2.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8B12","Gene synonym":[],"Ensembl":"ENSG00000170953","Gene description":"Olfactory receptor family 8 subfamily B member 12","Uniprot":["Q8NGG6"],"Chromosome":"11","Position":"124539635-124545333","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8B2","Gene synonym":[],"Ensembl":"ENSG00000284680","Gene description":"Olfactory receptor family 8 subfamily B member 2","Uniprot":["Q96RD0"],"Chromosome":"11","Position":"124382394-124384499","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"1.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"362","RNA single cell type specific nTPM":{"Early spermatids":"37.3","Late spermatids":"35.2"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8B3","Gene synonym":[],"Ensembl":"ENSG00000284609","Gene description":"Olfactory receptor family 8 subfamily B member 3","Uniprot":["Q8NGG8"],"Chromosome":"11","Position":"124395534-124399024","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"11.2","Late spermatids":"3.4"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8B4","Gene synonym":["OR8B4P"],"Ensembl":"ENSG00000280090","Gene description":"Olfactory receptor family 8 subfamily B member 4","Uniprot":["Q96RC9"],"Chromosome":"11","Position":"124423904-124424893","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8B8","Gene synonym":["TPCR85"],"Ensembl":"ENSG00000197125","Gene description":"Olfactory receptor family 8 subfamily B member 8","Uniprot":["Q15620"],"Chromosome":"11","Position":"124437445-124445696","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8D1","Gene synonym":["OR8D3","OST004"],"Ensembl":"ENSG00000196341","Gene description":"Olfactory receptor family 8 subfamily D member 1","Uniprot":["Q8WZ84"],"Chromosome":"11","Position":"124302831-124315099","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059510"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059510":"AB_2684045"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8D2","Gene synonym":[],"Ensembl":"ENSG00000279116","Gene description":"Olfactory receptor family 8 subfamily D member 2","Uniprot":["Q9GZM6"],"Chromosome":"11","Position":"124319238-124320288","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8D4","Gene synonym":[],"Ensembl":"ENSG00000181518","Gene description":"Olfactory receptor family 8 subfamily D member 4","Uniprot":["Q8NGM9"],"Chromosome":"11","Position":"123902167-123909229","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"2.7","Intestinal goblet cells":"1.7","Respiratory ciliated cells":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8G1","Gene synonym":["HSTPCR25","OR8G1P","TPCR25"],"Ensembl":"ENSG00000197849","Gene description":"Olfactory receptor family 8 subfamily G member 1","Uniprot":["Q15617"],"Chromosome":"11","Position":"124241095-124254364","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"12.8","Late spermatids":"5.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8G5","Gene synonym":["OR8G5P","OR8G6"],"Ensembl":"ENSG00000255298","Gene description":"Olfactory receptor family 8 subfamily G member 5","Uniprot":[],"Chromosome":"11","Position":"124256376-124266218","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"testis":"2.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"33.2","Late spermatids":"28.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8H1","Gene synonym":[],"Ensembl":"ENSG00000181693","Gene description":"Olfactory receptor family 8 subfamily H member 1","Uniprot":["Q8NGG4"],"Chromosome":"11","Position":"56288462-56292254","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8H2","Gene synonym":[],"Ensembl":"ENSG00000181767","Gene description":"Olfactory receptor family 8 subfamily H member 2","Uniprot":["Q8N162"],"Chromosome":"11","Position":"56103687-56107658","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"1.0"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8H3","Gene synonym":[],"Ensembl":"ENSG00000181761","Gene description":"Olfactory receptor family 8 subfamily H member 3","Uniprot":["Q8N146"],"Chromosome":"11","Position":"56122373-56123311","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8I2","Gene synonym":[],"Ensembl":"ENSG00000172154","Gene description":"Olfactory receptor family 8 subfamily I member 2","Uniprot":["Q8N0Y5"],"Chromosome":"11","Position":"56093277-56094286","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8J1","Gene synonym":[],"Ensembl":"ENSG00000172487","Gene description":"Olfactory receptor family 8 subfamily J member 1","Uniprot":["Q8NGP2"],"Chromosome":"11","Position":"56354291-56361511","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8J3","Gene synonym":[],"Ensembl":"ENSG00000167822","Gene description":"Olfactory receptor family 8 subfamily J member 3","Uniprot":["Q8NGG0"],"Chromosome":"11","Position":"56134721-56140201","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8K1","Gene synonym":[],"Ensembl":"ENSG00000150261","Gene description":"Olfactory receptor family 8 subfamily K member 1","Uniprot":["Q8NGG5"],"Chromosome":"11","Position":"56345945-56347031","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055233"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055233":"AB_2682749"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8K3","Gene synonym":[],"Ensembl":"ENSG00000280314","Gene description":"Olfactory receptor family 8 subfamily K member 3 (gene\/pseudogene)","Uniprot":["Q8NH51"],"Chromosome":"11","Position":"56315144-56320639","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8K5","Gene synonym":[],"Ensembl":"ENSG00000181752","Gene description":"Olfactory receptor family 8 subfamily K member 5","Uniprot":["Q8NH50"],"Chromosome":"11","Position":"56159394-56160317","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"stomach cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8S1","Gene synonym":[],"Ensembl":"ENSG00000284723","Gene description":"Olfactory receptor family 8 subfamily S member 1","Uniprot":["Q8NH09"],"Chromosome":"12","Position":"48525632-48528103","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045595"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA045595":"AB_10964447"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8U1","Gene synonym":[],"Ensembl":"ENSG00000172199","Gene description":"Olfactory receptor family 8 subfamily U member 1","Uniprot":["Q8NH10"],"Chromosome":"11","Position":"56375624-56376553","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR8U3","Gene synonym":["OR5R1","OR5R1P"],"Ensembl":"ENSG00000279961","Gene description":"Olfactory receptor family 8 subfamily U member 3","Uniprot":["Q8NH85"],"Chromosome":"11","Position":"56417258-56418232","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR9A2","Gene synonym":[],"Ensembl":"ENSG00000179468","Gene description":"Olfactory receptor family 9 subfamily A member 2","Uniprot":["Q8NGT5"],"Chromosome":"7","Position":"143026158-143027195","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"53","RNA tissue specific nTPM":{"brain":"5.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"38","RNA single cell type specific nTPM":{"Oligodendrocytes":"72.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR9A4","Gene synonym":[],"Ensembl":"ENSG00000258083","Gene description":"Olfactory receptor family 9 subfamily A member 4","Uniprot":["Q8NGU2"],"Chromosome":"7","Position":"141916399-141920625","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"28.8","Excitatory neurons":"4.1","Inhibitory neurons":"5.8","Microglial cells":"3.6","Oligodendrocyte precursor cells":"14.0","Oligodendrocytes":"6.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"1.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR9G1","Gene synonym":["OR9G5"],"Ensembl":"ENSG00000174914","Gene description":"Olfactory receptor family 9 subfamily G member 1","Uniprot":["Q8NH87"],"Chromosome":"11","Position":"56699095-56703884","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR9G4","Gene synonym":[],"Ensembl":"ENSG00000172457","Gene description":"Olfactory receptor family 9 subfamily G member 4","Uniprot":[],"Chromosome":"11","Position":"56741223-56748697","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR9I1","Gene synonym":[],"Ensembl":"ENSG00000172377","Gene description":"Olfactory receptor family 9 subfamily I member 1","Uniprot":["Q8NGQ6"],"Chromosome":"11","Position":"58116742-58125530","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR9K2","Gene synonym":[],"Ensembl":"ENSG00000170605","Gene description":"Olfactory receptor family 9 subfamily K member 2","Uniprot":["Q8NGE7"],"Chromosome":"12","Position":"55126406-55132750","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015808"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015808":"AB_2669306"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR9Q1","Gene synonym":[],"Ensembl":"ENSG00000186509","Gene description":"Olfactory receptor family 9 subfamily Q member 1","Uniprot":["Q8NGQ5"],"Chromosome":"11","Position":"58023881-58181616","Protein class":["G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"2.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OR9Q2","Gene synonym":["OR9Q2P"],"Ensembl":"ENSG00000186513","Gene description":"Olfactory receptor family 9 subfamily Q member 2","Uniprot":["Q8NGE9"],"Chromosome":"11","Position":"58189070-58194053","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Olfaction","Sensory transduction"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Paneth cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ORAI1","Gene synonym":["CRACM1","FLJ14466","TMEM142A"],"Ensembl":"ENSG00000276045","Gene description":"ORAI calcium release-activated calcium modulator 1","Uniprot":["Q96D31"],"Chromosome":"12","Position":"121626550-121642677","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Calcium transport","Immunity","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"60.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"122.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes","Skin - Keratinocyte (other)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016583"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016583":"AB_1848720"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.30e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"}},{"Gene":"ORAI2","Gene synonym":["C7orf19","CBCIP2","FLJ12474","FLJ14733","H_NH0514P08.8","TMEM142B"],"Ensembl":"ENSG00000160991","Gene description":"ORAI calcium release-activated calcium modulator 2","Uniprot":["Q96SN7"],"Chromosome":"7","Position":"102433106-102456825","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"116.3","Endometrial ciliated cells":"75.8","Glandular and luminal cells":"69.2","Plasma cells":"74.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"75.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055137","HPA065937"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA055137":"AB_2682712","HPA065937":"AB_2685581"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.49e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.65e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"}},{"Gene":"ORAI3","Gene synonym":["MGC13024","TMEM142C"],"Ensembl":"ENSG00000175938","Gene description":"ORAI calcium release-activated calcium modulator 3","Uniprot":["Q9BRQ5"],"Chromosome":"16","Position":"30949068-30956461","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"55.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015022"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015022":"AB_1854807"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.87e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-3"}},{"Gene":"ORC3","Gene synonym":["IMAGE50150","LATHEO","ORC3L"],"Ensembl":"ENSG00000135336","Gene description":"Origin recognition complex subunit 3","Uniprot":["Q9UBD5"],"Chromosome":"6","Position":"87590067-87667453","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA replication"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039553","HPA053748"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA039553":"AB_2676566","HPA053748":"AB_2682247"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.89e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.23e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"ORMDL1","Gene synonym":[],"Ensembl":"ENSG00000128699","Gene description":"ORMDL sphingolipid biosynthesis regulator 1","Uniprot":["Q9P0S3"],"Chromosome":"2","Position":"189770267-189784364","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065643"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA065643":"AB_2685525"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.04e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.84e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.49e-5"}},{"Gene":"ORMDL2","Gene synonym":["adoplin-2","HSPC160","MST095","MSTP095"],"Ensembl":"ENSG00000123353","Gene description":"ORMDL sphingolipid biosynthesis regulator 2","Uniprot":["Q53FV1"],"Chromosome":"12","Position":"55818041-55821879","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065643"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA065643":"AB_2685525"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.30e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.75e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"}},{"Gene":"ORMDL3","Gene synonym":[],"Ensembl":"ENSG00000172057","Gene description":"ORMDL sphingolipid biosynthesis regulator 3","Uniprot":["Q8N138"],"Chromosome":"17","Position":"39921041-39927601","Protein class":["Disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Asthma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"234.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"209.2","Late spermatids":"380.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065643"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA065643":"AB_2685525"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.29e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.18e-4"}},{"Gene":"OSBPL5","Gene synonym":["KIAA1534","OBPH1","ORP5"],"Ensembl":"ENSG00000021762","Gene description":"Oxysterol binding protein like 5","Uniprot":["Q9H0X9"],"Chromosome":"11","Position":"3087107-3166739","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"54.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"3.6","gdT-cell":"9.0","intermediate monocyte":"4.7","memory CD8 T-cell":"3.3","myeloid DC":"3.0","naive CD8 T-cell":"3.4","NK-cell":"11.0","non-classical monocyte":"11.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038335","HPA038712","HPA058727"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA038335":"AB_2675963","HPA038712":"AB_10675949","HPA058727":"AB_2683799"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"}},{"Gene":"OSBPL6","Gene synonym":["ORP6"],"Ensembl":"ENSG00000079156","Gene description":"Oxysterol binding protein like 6","Uniprot":["Q9BZF3"],"Chromosome":"2","Position":"178194481-178402893","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"33.8","tongue":"20.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"272.7","Excitatory neurons":"309.7","Inhibitory neurons":"395.1","Oligodendrocyte precursor cells":"128.5","Skeletal myocytes":"138.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Lung - Respiratory ciliated cells","Skin - Keratinocyte (other)","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032131"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA032131":"AB_10670963"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-6"}},{"Gene":"OSBPL8","Gene synonym":["MST120","MSTP120","ORP8","OSBP10"],"Ensembl":"ENSG00000091039","Gene description":"Oxysterol binding protein like 8","Uniprot":["Q9BZF1"],"Chromosome":"12","Position":"76351797-76559809","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Fibroblasts","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001309"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001309":"AB_1079530"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.79e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-3"}},{"Gene":"OSCAR","Gene synonym":[],"Ensembl":"ENSG00000170909","Gene description":"Osteoclast associated Ig-like receptor","Uniprot":["Q8IYS5"],"Chromosome":"19","Position":"54094668-54102692","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"13.6","lung":"28.4","lymphoid tissue":"29.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hofbauer cells":"50.1","Kupffer cells":"31.8","Langerhans cells":"16.1","Macrophages":"43.9","monocytes":"41.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"36","RNA blood cell specific nTPM":{"classical monocyte":"43.0","eosinophil":"26.6","intermediate monocyte":"28.8","myeloid DC":"20.3","neutrophil":"40.0","non-classical monocyte":"27.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"79","RNA blood lineage specific nTPM":{"dendritic cells":"20.3","granulocytes":"40.0","monocytes":"43.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"7.8","thyroid cancer":"5.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Kidney - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073996"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"84000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA073996":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.71e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"}},{"Gene":"OSMR","Gene synonym":["OSMRB","OSMRbeta"],"Ensembl":"ENSG00000145623","Gene description":"Oncostatin M receptor","Uniprot":["Q99650"],"Chromosome":"5","Position":"38845858-38945596","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Amyloidosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"115.1","Exocrine glandular cells":"69.6","Mucus glandular cells":"88.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017278"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"51000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA017278":"AB_1854818"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.87e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.96e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"}},{"Gene":"OSR2","Gene synonym":["FLJ90037"],"Ensembl":"ENSG00000164920","Gene description":"Odd-skipped related transciption factor 2","Uniprot":["Q8N2R0"],"Chromosome":"8","Position":"98944403-98952104","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"166.1","endometrium 1":"155.1","fallopian tube":"155.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"245.2","Extravillous trophoblasts":"167.5","Leydig cells":"816.0","Peritubular cells":"774.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Kidney - Fibroblasts","Lung - Fibroblast_2","Skin - Fibroblast_2","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052425","HPA063486"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA052425":"AB_2681826","HPA063486":"AB_2685022"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.44e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-3"}},{"Gene":"OST4","Gene synonym":[],"Ensembl":"ENSG00000228474","Gene description":"Oligosaccharyltransferase complex subunit 4, non-catalytic","Uniprot":["P0C6T2"],"Chromosome":"2","Position":"27070472-27071654","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.35e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-2"}},{"Gene":"OSTC","Gene synonym":["DC2"],"Ensembl":"ENSG00000198856","Gene description":"Oligosaccharyltransferase complex non-catalytic subunit","Uniprot":["Q9NRP0"],"Chromosome":"4","Position":"108650585-108667820","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"702.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.44e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.66e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.84e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.31e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"}},{"Gene":"OSTM1","Gene synonym":["GL","HSPC019"],"Ensembl":"ENSG00000081087","Gene description":"Osteoclastogenesis associated transmembrane protein 1","Uniprot":["Q86WC4"],"Chromosome":"6","Position":"108041409-108165854","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Osteopetrosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Melanocytes":"205.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010851"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA010851":"AB_1079533"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.36e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.26e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"}},{"Gene":"OTOA","Gene synonym":["CT108","DFNB22"],"Ensembl":"ENSG00000155719","Gene description":"Otoancorin","Uniprot":["Q7RTW8"],"Chromosome":"16","Position":"21663968-21761935","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lymphoid tissue":"1.8","testis":"4.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hofbauer cells":"44.1","Late spermatids":"13.1","Macrophages":"14.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"dendritic cells":"1.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"ovarian cancer":"1.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Lung - Macrophages","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041405"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"51000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041405":"AB_10796344"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"}},{"Gene":"OTOF","Gene synonym":["DFNB6","DFNB9","FER1L2"],"Ensembl":"ENSG00000115155","Gene description":"Otoferlin","Uniprot":["Q9HC10"],"Chromosome":"2","Position":"26457203-26558756","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Neuropathy","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"bone marrow":"6.4","brain":"23.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"1.3","Inhibitory neurons":"3.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"2.4","lymphoma":"2.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012410"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012410":"AB_1854836"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-5"}},{"Gene":"OTOP1","Gene synonym":[],"Ensembl":"ENSG00000163982","Gene description":"Otopetrin 1","Uniprot":["Q7RTM1"],"Chromosome":"4","Position":"4188726-4226929","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Biomineralization","Hydrogen ion transport","Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035599"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035599":"AB_10600924"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OTOP2","Gene synonym":[],"Ensembl":"ENSG00000183034","Gene description":"Otopetrin 2","Uniprot":["Q7RTS6"],"Chromosome":"17","Position":"74922950-74933912","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"20.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"34","RNA single cell type specific nTPM":{"Paneth cells":"1035.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"1.9"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"12","RNA mouse brain regional specific nTPM":{"olfactory bulb":"12.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024524","HPA053090"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA024524":"AB_2671592","HPA053090":"AB_2682041"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"}},{"Gene":"OTOP3","Gene synonym":[],"Ensembl":"ENSG00000182938","Gene description":"Otopetrin 3","Uniprot":[],"Chromosome":"17","Position":"74935898-74949992","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"intestine":"79.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Paneth cells":"71.0","Proximal enterocytes":"14.2","Squamous epithelial cells":"7.5","Suprabasal keratinocytes":"22.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"3.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"cervical cancer":"28.9","thyroid cancer":"9.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.86e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"OTULINL","Gene synonym":["FAM105A","FLJ11127","NET20"],"Ensembl":"ENSG00000145569","Gene description":"OTU deubiquitinase with linear linkage specificity like","Uniprot":["Q9NUU6"],"Chromosome":"5","Position":"14581792-14616180","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"30.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"180.0","dendritic cells":"183.1","Hofbauer cells":"105.2","Langerhans cells":"91.8","Spermatocytes":"98.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Skeletal muscle - Macrophages","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046638"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046638":"AB_2679731"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.62e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-3"}},{"Gene":"OXA1L","Gene synonym":["MGC133129","OXA1"],"Ensembl":"ENSG00000155463","Gene description":"OXA1L mitochondrial inner membrane protein","Uniprot":["Q15070"],"Chromosome":"14","Position":"22766522-22773042","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003531"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA003531":"AB_1079539"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.82e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"}},{"Gene":"OXER1","Gene synonym":["GPCR","GPR170","TG1019"],"Ensembl":"ENSG00000162881","Gene description":"Oxoeicosanoid receptor 1","Uniprot":["Q8TDS5"],"Chromosome":"2","Position":"42762481-42764261","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"56.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"6.5","Melanocytes":"5.2","Paneth cells":"5.3","Proximal enterocytes":"14.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"12.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"67.0","eosinophil":"144.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"79","RNA blood lineage specific nTPM":{"granulocytes":"144.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"2.8"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051433"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051433":"AB_2681485"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"}},{"Gene":"OXGR1","Gene synonym":["aKGR","GPR80","GPR99","P2RY15","P2Y15"],"Ensembl":"ENSG00000165621","Gene description":"Oxoglutarate receptor 1","Uniprot":["Q96P68"],"Chromosome":"13","Position":"96985719-96994730","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"56.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"myeloid DC":"1.2","plasmacytoid DC":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"2.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"8.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Breast - Breast glandular cells (progenitors)","Kidney - Intercalated cells","Pancreas - Beta cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067673"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA067673":"AB_2685883"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"}},{"Gene":"OXTR","Gene synonym":[],"Ensembl":"ENSG00000180914","Gene description":"Oxytocin receptor","Uniprot":["P30559"],"Chromosome":"3","Position":"8750381-8769628","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"14.7","breast":"54.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Breast myoepithelial cells":"160.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"7.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"30.6"},"RNA tissue cell type enrichment":["Pancreas - Ductal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"}},{"Gene":"P2RX1","Gene synonym":["P2X1"],"Ensembl":"ENSG00000108405","Gene description":"Purinergic receptor P2X 1","Uniprot":["P51575"],"Chromosome":"17","Position":"3896592-3916476","Protein class":["Predicted membrane proteins"],"Biological process":["Apoptosis","Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"42.0","pancreas":"65.1","urinary bladder":"75.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"49.0","Erythroid cells":"16.7","granulocytes":"57.5","Kupffer cells":"17.6","monocytes":"45.5","Plasma cells":"36.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"46.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"30","RNA blood lineage specific nTPM":{"dendritic cells":"15.1","granulocytes":"23.5","monocytes":"46.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"14.1","Myeloma":"14.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Skin - Smooth muscle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"midbrain":"1.3"},"Antibody":["HPA057678"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA057678":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"}},{"Gene":"P2RX2","Gene synonym":["DFNA41","P2X2"],"Ensembl":"ENSG00000187848","Gene description":"Purinergic receptor P2X 2","Uniprot":["Q9UBL9"],"Chromosome":"12","Position":"132618776-132622388","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Hearing","Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.3","epididymis":"21.8","prostate":"14.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"4.1","Breast glandular cells":"1.6","Endometrial ciliated cells":"2.3","Fibroblasts":"5.0","Gastric mucus-secreting cells":"1.2","Pancreatic endocrine cells":"3.4","Peritubular cells":"2.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.3"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"amygdala":"9.2","cerebral cortex":"11.3","hippocampal formation":"10.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"5.5"},"RNA tissue cell type enrichment":["Colon - Fibroblasts","Pancreas - Beta cells","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"}},{"Gene":"P2RX3","Gene synonym":["P2X3"],"Ensembl":"ENSG00000109991","Gene description":"Purinergic receptor P2X 3","Uniprot":["P56373"],"Chromosome":"11","Position":"57338352-57372396","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"2.9","liver":"1.7","testis":"5.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"27.0","Late spermatids":"26.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"74","RNA cell line specific nTPM":{"Neuroblastoma":"23.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Liver - Hepatocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057776"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057776":"AB_2683526"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"}},{"Gene":"P2RX4","Gene synonym":["P2X4"],"Ensembl":"ENSG00000135124","Gene description":"Purinergic receptor P2X 4","Uniprot":["Q99571"],"Chromosome":"12","Position":"121209861-121234106","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"136.7","Hofbauer cells":"119.9","Intestinal goblet cells":"95.5","Proximal enterocytes":"96.3","Syncytiotrophoblasts":"159.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039494"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039494":"AB_10969132"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.30e-10"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-3"}},{"Gene":"P2RX5","Gene synonym":["LRH-1","P2X5"],"Ensembl":"ENSG00000083454","Gene description":"Purinergic receptor P2X 5","Uniprot":["Q93086"],"Chromosome":"17","Position":"3672199-3696240","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"24.7","lymphoid tissue":"78.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"115.4","Plasma cells":"31.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"memory B-cell":"76.4","naive B-cell":"84.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"B-cells":"84.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"60.7","Myeloma":"38.7"},"RNA tissue cell type enrichment":["Breast - Plasma cells","Lung - B-cells","Thyroid - Plasma cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021948","HPA067827"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA021948":"AB_1854878","HPA067827":"AB_2685908"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"}},{"Gene":"P2RX6","Gene synonym":["MGC129625","P2RXL1","P2X6","P2XM"],"Ensembl":"ENSG00000099957","Gene description":"Purinergic receptor P2X 6","Uniprot":["O15547"],"Chromosome":"22","Position":"21009808-21028830","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"3.4","skeletal muscle":"12.4","tongue":"7.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"7.2","Excitatory neurons":"8.8","Horizontal cells":"10.9","Inhibitory neurons":"7.8","Oligodendrocyte precursor cells":"4.8","Skeletal myocytes":"5.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"1.0","melanoma":"2.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"4.2"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028776","HPA028777"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028776":"AB_2672771","HPA028777":"AB_2672772"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-3"}},{"Gene":"P2RX7","Gene synonym":["MGC20089","P2X7"],"Ensembl":"ENSG00000089041","Gene description":"Purinergic receptor P2X 7","Uniprot":["Q99572"],"Chromosome":"12","Position":"121132819-121188032","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"47.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"52.0","Langerhans cells":"83.2","Melanocytes":"48.8","Oligodendrocyte precursor cells":"84.2","Oligodendrocytes":"147.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"7.2","melanoma":"19.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"2.9","gdT-cell":"1.3","intermediate monocyte":"4.5","myeloid DC":"2.6","non-classical monocyte":"3.3","T-reg":"1.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"2.6","monocytes":"4.5","T-cells":"1.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Brain cancer":"4.5","Leukemia":"5.5","Myeloma":"14.5","skin cancer":"11.5"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Skin - Keratinocyte (other)","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034968","HPA042013","HPA044141"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034968":"AB_10673105","HPA042013":"AB_2677797","HPA044141":"AB_2678830"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"}},{"Gene":"P2RY1","Gene synonym":["P2Y1","SARCC"],"Ensembl":"ENSG00000169860","Gene description":"Purinergic receptor P2Y1","Uniprot":["P47900"],"Chromosome":"3","Position":"152835131-152841439","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"25.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"30.1","monocytes":"49.3","Prostatic glandular cells":"62.6","Squamous epithelial cells":"46.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"6.0","non-classical monocyte":"2.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"6.0","monocytes":"2.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"15.0","Gallbladder cancer":"11.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Skeletal muscle - Skeletal myocytes","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015577"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015577":"AB_1854882"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.04e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"}},{"Gene":"P2RY10","Gene synonym":["P2Y10"],"Ensembl":"ENSG00000078589","Gene description":"P2Y receptor family member 10","Uniprot":["O00398"],"Chromosome":"X","Position":"78945332-78963727","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"27.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"111.8","Langerhans cells":"74.1","NK-cells":"27.5","Plasma cells":"36.2","Schwann cells":"38.3","T-cells":"85.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"256.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Leukemia":"4.5","lymphoma":"14.3","Myeloma":"17.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Kidney - T-cells","Liver - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036757","HPA065766"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036757":"AB_10696786","HPA065766":"AB_2685556"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"}},{"Gene":"P2RY11","Gene synonym":["P2Y11"],"Ensembl":"ENSG00000244165","Gene description":"Purinergic receptor P2Y11","Uniprot":["Q96G91"],"Chromosome":"19","Position":"10111693-10115372","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"33.5","NK-cells":"13.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"18.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"NK-cells":"13.9","T-cells":"18.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014232"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014232":"AB_1854883"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.77e-4"}},{"Gene":"P2RY12","Gene synonym":["HORK3","P2Y12","SP1999"],"Ensembl":"ENSG00000169313","Gene description":"Purinergic receptor P2Y12","Uniprot":["Q9H244"],"Chromosome":"3","Position":"151336843-151384753","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"13.8","lymphoid tissue":"9.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Microglial cells":"410.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"glioma":"17.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"8.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"3.2","monocytes":"8.3"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013796","HPA014518"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013796":"AB_1854884","HPA014518":"AB_2669027"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"}},{"Gene":"P2RY13","Gene synonym":["FKSG77","GPR86","GPR94","P2Y13"],"Ensembl":"ENSG00000181631","Gene description":"Purinergic receptor P2Y13","Uniprot":["Q9BPV8"],"Chromosome":"3","Position":"151326312-151329549","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"25.1","lymphoid tissue":"36.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Hofbauer cells":"24.2","Kupffer cells":"38.1","Macrophages":"63.2","Microglial cells":"64.8","monocytes":"67.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"581.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"581.5","monocytes":"185.6"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Macrophages","Liver - Kupffer cells","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049047"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049047":"AB_2680611"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-1"}},{"Gene":"P2RY14","Gene synonym":["GPR105","KIAA0001"],"Ensembl":"ENSG00000174944","Gene description":"Purinergic receptor P2Y14","Uniprot":["Q15391"],"Chromosome":"3","Position":"151212117-151278542","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"24.6","placenta":"31.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"208.0","Endometrial stromal cells":"46.9","Excitatory neurons":"40.7","Langerhans cells":"72.0","Schwann cells":"43.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"eosinophil":"230.1","plasmacytoid DC":"98.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"98.0","granulocytes":"230.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.4","Rhabdoid":"1.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022646"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022646":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"}},{"Gene":"P2RY2","Gene synonym":["P2U"],"Ensembl":"ENSG00000175591","Gene description":"Purinergic receptor P2Y2","Uniprot":["P41231"],"Chromosome":"11","Position":"73218281-73242427","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"29.7","skeletal muscle":"50.2","tongue":"31.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"16.5","Proximal enterocytes":"15.3","Squamous epithelial cells":"15.6","Syncytiotrophoblasts":"14.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"57.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"granulocytes":"57.6","monocytes":"20.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Urothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022642"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB022642":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.19e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"}},{"Gene":"P2RY4","Gene synonym":["NRU","P2P","P2Y4","UNR"],"Ensembl":"ENSG00000186912","Gene description":"Pyrimidinergic receptor P2Y4","Uniprot":["P51582"],"Chromosome":"X","Position":"70258170-70259764","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"2.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Intestinal goblet cells":"1.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022644"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022644":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"}},{"Gene":"P2RY6","Gene synonym":["P2Y6"],"Ensembl":"ENSG00000171631","Gene description":"Pyrimidinergic receptor P2Y6","Uniprot":["Q15077"],"Chromosome":"11","Position":"73264498-73305103","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"32.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Cytotrophoblasts":"165.0","dendritic cells":"516.7","Syncytiotrophoblasts":"376.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"myeloid DC":"27.2","plasmacytoid DC":"87.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"87.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074751"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074751":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.50e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"P2RY8","Gene synonym":["P2Y8"],"Ensembl":"ENSG00000182162","Gene description":"P2Y receptor family member 8","Uniprot":["Q86VZ1"],"Chromosome":"X","Position":"1462581-1537185","Protein class":["Cancer-related genes","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"31.2","lymphoid tissue":"40.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"42.1","Kupffer cells":"15.6","NK-cells":"72.2","Plasma cells":"37.5","T-cells":"43.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"32","RNA cell line specific nTPM":{"Leukemia":"62.4","lymphoma":"76.5","Myeloma":"48.9"},"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Kidney - Endothelial cells","Lung - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003631"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003631":"AB_1079543"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.80e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.54e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"}},{"Gene":"P4HB","Gene synonym":["DSI","ERBA2L","GIT","P4Hbeta","PDI","PDIA1","PO4DB","PO4HB","PROHB"],"Ensembl":"ENSG00000185624","Gene description":"Prolyl 4-hydroxylase subunit beta","Uniprot":["P07237"],"Chromosome":"17","Position":"81843159-81860856","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone","Isomerase"],"Disease involvement":["Craniosynostosis","Disease variant","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"1856.8","pancreas":"2446.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"1521.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Stomach - Chief cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012463","HPA018884"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB012463":null,"HPA018884":"AB_1854896"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.30e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-3"}},{"Gene":"P4HTM","Gene synonym":["EGLN4","FLJ20262","HIFPH4","P4H-TM","PH-4","PH4","PHD4"],"Ensembl":"ENSG00000178467","Gene description":"Prolyl 4-hydroxylase, transmembrane","Uniprot":["Q9NXG6"],"Chromosome":"3","Position":"48989889-49007153","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"161.3","Respiratory ciliated cells":"201.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007199"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007199":"AB_1855272"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.18e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.28e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-3"}},{"Gene":"PAAF1","Gene synonym":["FLJ11848","Rpn14","WDR71"],"Ensembl":"ENSG00000175575","Gene description":"Proteasomal ATPase associated factor 1","Uniprot":["Q9BRP4"],"Chromosome":"11","Position":"73876699-73931114","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"130.1"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039952","HPA040020"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA039952":"AB_10793925","HPA040020":"AB_2676802"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-1"}},{"Gene":"PABPC1L","Gene synonym":["C20orf119","dJ1069P2.3","ePAB","PABPC1L1"],"Ensembl":"ENSG00000101104","Gene description":"Poly(A) binding protein cytoplasmic 1 like","Uniprot":["Q4VXU2"],"Chromosome":"20","Position":"44910060-44959035","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066650"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA066650":"AB_2685698"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.80e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.00e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.84e-4"}},{"Gene":"PACC1","Gene synonym":["C1orf75","FLJ10874","PAC","TMEM206"],"Ensembl":"ENSG00000065600","Gene description":"Proton activated chloride channel 1","Uniprot":["Q9H813"],"Chromosome":"1","Position":"212363928-212414901","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"32.3","Oligodendrocytes":"60.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008540"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008540":"AB_10794083"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.71e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"}},{"Gene":"PACRG","Gene synonym":["FLJ32724","Glup","HAK005771","PARK2CRG"],"Ensembl":"ENSG00000112530","Gene description":"Parkin coregulated","Uniprot":["Q96M98"],"Chromosome":"6","Position":"162727132-163315492","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"35.7","testis":"29.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"289.5","Excitatory neurons":"122.4","Inhibitory neurons":"170.7","Late spermatids":"393.9","Respiratory ciliated cells":"110.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Cardiomyocytes","Kidney - Intercalated cells","Liver - Hepatocytes","Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066293"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066293":"AB_2685652"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.55e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"}},{"Gene":"PAG1","Gene synonym":["CBP","PAG"],"Ensembl":"ENSG00000076641","Gene description":"Phosphoprotein membrane anchor with glycosphingolipid microdomains 1","Uniprot":["Q9NWQ8"],"Chromosome":"8","Position":"80967810-81112068","Protein class":["Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"187.1","Melanocytes":"203.8","Microglial cells":"162.4","monocytes":"420.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"15.3","lymphoma":"22.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001632","HPA066527"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA001632":"AB_1079557","HPA066527":"AB_2685685"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.82e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-3"}},{"Gene":"PAK3","Gene synonym":["bPAK","hPAK3","MRX30","MRX47"],"Ensembl":"ENSG00000077264","Gene description":"P21 (RAC1) activated kinase 3","Uniprot":["O75914"],"Chromosome":"X","Position":"110944285-111227361","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Allosteric enzyme","Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"31.9","pancreas":"42.7","pituitary gland":"13.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"92.9","Excitatory neurons":"358.7","Inhibitory neurons":"315.5","Oligodendrocyte precursor cells":"158.8","Peritubular cells":"81.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"1.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"MAIT T-cell":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"1.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044791","HPA060219"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA044791":null,"HPA060219":"AB_2684223"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"}},{"Gene":"PALD1","Gene synonym":["KIAA1274","PALD"],"Ensembl":"ENSG00000107719","Gene description":"Phosphatase domain containing paladin 1","Uniprot":["Q9ULE6"],"Chromosome":"10","Position":"70478767-70568450","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"dendritic cells":"43.0","Microglial cells":"125.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"plasmacytoid DC":"5.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"27","RNA blood lineage specific nTPM":{"dendritic cells":"5.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Lung - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015696","HPA017343"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015696":"AB_1852399","HPA017343":"AB_1852397"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-3"}},{"Gene":"PAM","Gene synonym":["PAL","PHM"],"Ensembl":"ENSG00000145730","Gene description":"Peptidylglycine alpha-amidating monooxygenase","Uniprot":["P19021"],"Chromosome":"5","Position":"102753981-103031105","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Lyase","Monooxygenase","Multifunctional enzyme","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"1560.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1274.5","Inhibitory neurons":"477.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026119","HPA042260"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"98000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB026119":null,"HPA042260":"AB_2677919"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.63e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.20e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-3"}},{"Gene":"PANK2","Gene synonym":["C20orf48","FLJ11729","HARP","HSS","NBIA1","PKAN"],"Ensembl":"ENSG00000125779","Gene description":"Pantothenate kinase 2","Uniprot":["Q9BZ23"],"Chromosome":"20","Position":"3888839-3929887","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Angiogenesis","Coenzyme A biosynthesis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008440"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008440":"AB_1079559"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"}},{"Gene":"PANX1","Gene synonym":["MRS1","PX1","UNQ2529"],"Ensembl":"ENSG00000110218","Gene description":"Pannexin 1","Uniprot":["Q96RD7"],"Chromosome":"11","Position":"94128841-94181968","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Differentiation","Ion transport","Oogenesis","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"67.7","Extravillous trophoblasts":"36.4","Suprabasal keratinocytes":"39.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016930"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA016930":"AB_1854954"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.09e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"}},{"Gene":"PANX2","Gene synonym":["hPANX2","PX2"],"Ensembl":"ENSG00000073150","Gene description":"Pannexin 2","Uniprot":["Q96RD6"],"Chromosome":"22","Position":"50170731-50180295","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"51.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"13.0","dendritic cells":"13.1","Excitatory neurons":"13.1","Horizontal cells":"13.5","Inhibitory neurons":"15.4","Muller glia cells":"25.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.9"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"granulocytes":"1.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004624","HPA039117"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA004624":null,"HPA039117":"AB_10805354"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"}},{"Gene":"PANX3","Gene synonym":["Px3"],"Ensembl":"ENSG00000154143","Gene description":"Pannexin 3","Uniprot":["Q96QZ0"],"Chromosome":"11","Position":"124611428-124620356","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"1.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PAPOLA","Gene synonym":["PAP"],"Ensembl":"ENSG00000090060","Gene description":"Poly(A) polymerase alpha","Uniprot":["P51003"],"Chromosome":"14","Position":"96501433-96567111","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["mRNA processing"],"Molecular function":["RNA-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"752.1","Syncytiotrophoblasts":"1045.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001788"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA001788":"AB_1079564"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.41e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-1"}},{"Gene":"PAPOLB","Gene synonym":["PAPT"],"Ensembl":"ENSG00000218823","Gene description":"Poly(A) polymerase beta","Uniprot":["Q9NRJ5"],"Chromosome":"7","Position":"4857738-4862030","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["mRNA processing"],"Molecular function":["RNA-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"testis":"29.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"28","RNA single cell type specific nTPM":{"Early spermatids":"98.4","Late spermatids":"93.3","Spermatocytes":"33.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"1.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047285"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA047285":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PAPOLG","Gene synonym":["FLJ12972"],"Ensembl":"ENSG00000115421","Gene description":"Poly(A) polymerase gamma","Uniprot":["Q9BWT3"],"Chromosome":"2","Position":"60756253-60802086","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["mRNA processing"],"Molecular function":["RNA-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017795","HPA035349","HPA035350"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"CAB017795":null,"HPA035349":"AB_2674583","HPA035350":"AB_2674584"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"}},{"Gene":"PAPPA2","Gene synonym":["PAPP-A2","PAPPE","PLAC3"],"Ensembl":"ENSG00000116183","Gene description":"Pappalysin 2","Uniprot":["Q9BXP8"],"Chromosome":"1","Position":"176463171-176845601","Protein class":["Enzymes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"placenta":"56.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"25.3","Enteroendocrine cells":"60.0","Extravillous trophoblasts":"98.8","Muller glia cells":"32.9","Oligodendrocytes":"35.5","Syncytiotrophoblasts":"77.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"1.8","renal cancer":"1.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"1.8"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Testis - Spermatogonia","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"5.6"},"Antibody":["HPA018412","HPA018430"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Secreted in female reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA018412":"AB_1854962","HPA018430":"AB_1854961"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"}},{"Gene":"PAQR3","Gene synonym":[],"Ensembl":"ENSG00000163291","Gene description":"Progestin and adipoQ receptor family member 3","Uniprot":["Q6TCH7"],"Chromosome":"4","Position":"78887127-78939438","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"57.8","Excitatory neurons":"57.3","Late spermatids":"149.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"}},{"Gene":"PAQR4","Gene synonym":["FLJ30002"],"Ensembl":"ENSG00000162073","Gene description":"Progestin and adipoQ receptor family member 4","Uniprot":["Q8N4S7"],"Chromosome":"16","Position":"2969270-2973484","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"124.5","retina":"63.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"131.0","Oligodendrocytes":"58.5","Rod photoreceptor cells":"129.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"non-classical monocyte":"3.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"monocytes":"3.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skeletal muscle - Skeletal myocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068394"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA068394":"AB_2685980"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.01e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-3"}},{"Gene":"PAQR5","Gene synonym":["FLJ20190","MPRG"],"Ensembl":"ENSG00000137819","Gene description":"Progestin and adipoQ receptor family member 5","Uniprot":["Q9NXK6"],"Chromosome":"15","Position":"69298912-69407780","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Oogenesis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"52.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"27.8","granulocytes":"35.7","Late spermatids":"125.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"8.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"1.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Cholangiocyte","Stomach - Parietal cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076729"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA076729":"AB_2686813"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.15e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.47e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"}},{"Gene":"PAQR6","Gene synonym":["FLJ22672","PRdelta"],"Ensembl":"ENSG00000160781","Gene description":"Progestin and adipoQ receptor family member 6","Uniprot":["Q6TCH4"],"Chromosome":"1","Position":"156243320-156248117","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"37","RNA tissue specific nTPM":{"brain":"674.6","choroid plexus":"196.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"42.7","Muller glia cells":"58.6","Oligodendrocytes":"61.5","Schwann cells":"15.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"34.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"NK-cell":"5.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"NK-cells":"5.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.58e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.86e-4"}},{"Gene":"PAQR7","Gene synonym":["MPRA","mSR"],"Ensembl":"ENSG00000182749","Gene description":"Progestin and adipoQ receptor family member 7","Uniprot":["Q86WK9"],"Chromosome":"1","Position":"25861484-25875708","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Oogenesis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Late spermatids":"1980.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Liver - Hepatocytes","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046936"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046936":"AB_2679869"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"PAQR8","Gene synonym":["C6orf33","LMPB1","MPRB"],"Ensembl":"ENSG00000170915","Gene description":"Progestin and adipoQ receptor family member 8","Uniprot":["Q8TEZ7"],"Chromosome":"6","Position":"52361421-52407777","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Oogenesis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"144.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"163.2","Distal enterocytes":"111.2","Microglial cells":"72.1","Oligodendrocytes":"281.5","Paneth cells":"82.4","Proximal enterocytes":"99.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"34.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064625"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA064625":"AB_2685304"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.61e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.40e-4"}},{"Gene":"PAQR9","Gene synonym":["FLJ41938"],"Ensembl":"ENSG00000188582","Gene description":"Progestin and adipoQ receptor family member 9","Uniprot":["Q6ZVX9"],"Chromosome":"3","Position":"142949164-142963674","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"13.5","retina":"9.6","testis":"20.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"42.9","Erythroid cells":"38.2","Hepatocytes":"24.8","Late spermatids":"98.9","Rod photoreceptor cells":"19.5","Syncytiotrophoblasts":"47.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"liver cancer":"5.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"2.2"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052798"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052798":"AB_2681955"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"}},{"Gene":"PARL","Gene synonym":["PRO2207","PSARL","PSARL1","RHBDS1"],"Ensembl":"ENSG00000175193","Gene description":"Presenilin associated rhomboid like","Uniprot":["Q9H300"],"Chromosome":"3","Position":"183829271-183884933","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019545"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA019545":"AB_1855796"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.11e-5"}},{"Gene":"PARM1","Gene synonym":["Cipar1","DKFZP564O0823","WSC4"],"Ensembl":"ENSG00000169116","Gene description":"Prostate androgen-regulated mucin-like protein 1","Uniprot":["Q6UWI2"],"Chromosome":"4","Position":"74933095-75050115","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"190.6","Distal enterocytes":"284.3","Intestinal goblet cells":"102.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"56.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"memory B-cell":"8.1","myeloid DC":"4.0","naive B-cell":"5.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"B-cells":"8.1","dendritic cells":"4.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"38.8"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Heart muscle - Cardiomyocytes","Kidney - Fibroblasts","Lung - Alveolar cells type 2","Skin - Outer root sheath cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038236"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm","Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038236":"AB_10675789"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.78e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"}},{"Gene":"PARN","Gene synonym":["DAN"],"Ensembl":"ENSG00000140694","Gene description":"Poly(A)-specific ribonuclease","Uniprot":["O95453"],"Chromosome":"16","Position":"14435700-14632728","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Nonsense-mediated mRNA decay"],"Molecular function":["Exonuclease","Hydrolase","Nuclease","RNA-binding"],"Disease involvement":["Disease variant","Dyskeratosis congenita"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006314","CAB011673","HPA012010"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"CAB011673":"AB_778216","HPA006314":"AB_1079567","HPA012010":"AB_1854976"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"}},{"Gene":"PARP16","Gene synonym":["ARTD15","C15orf30","FLJ20509","FLJ25281","pART15"],"Ensembl":"ENSG00000138617","Gene description":"Poly(ADP-ribose) polymerase family member 16","Uniprot":["Q8N5Y8"],"Chromosome":"15","Position":"65234460-65300618","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Unfolded protein response"],"Molecular function":["Glycosyltransferase","Nucleotidyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"32.6","Spermatogonia":"30.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017081"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017081":"AB_10963218"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"}},{"Gene":"PARP4","Gene synonym":["ADPRTL1","ARTD4","p193","VAULT3","VPARP","VWA5C"],"Ensembl":"ENSG00000102699","Gene description":"Poly(ADP-ribose) polymerase family member 4","Uniprot":["Q9UKK3"],"Chromosome":"13","Position":"24420931-24512778","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Nucleotidyltransferase","Ribonucleoprotein","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011739"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA011739":"AB_1854986"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.21e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-3"}},{"Gene":"PARVA","Gene synonym":["FLJ10793","FLJ12254","MXRA2"],"Ensembl":"ENSG00000197702","Gene description":"Parvin alpha","Uniprot":["Q9NVD7"],"Chromosome":"11","Position":"12377563-12535356","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Cell adhesion","Cell shape","Chemotaxis","Cilium biogenesis\/degradation"],"Molecular function":["Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"T-cells":"1.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Colon - Smooth muscle cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005964"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Actin filaments","Focal adhesion sites","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7300000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Actin filaments","Focal adhesion sites"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA005964":"AB_1079569"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.76e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.19e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"}},{"Gene":"PARVB","Gene synonym":["CGI-56"],"Ensembl":"ENSG00000188677","Gene description":"Parvin beta","Uniprot":["Q9HBI1"],"Chromosome":"22","Position":"43999211-44172939","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Actin-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"195.9","tongue":"170.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"161.3","Erythroid cells":"108.3","granulocytes":"93.0","Hofbauer cells":"88.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"20.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003568","HPA072217"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Actin filaments","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA003568":null,"HPA072217":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-3"}},{"Gene":"PARVG","Gene synonym":[],"Ensembl":"ENSG00000138964","Gene description":"Parvin gamma","Uniprot":["Q9HBI0"],"Chromosome":"22","Position":"44172956-44219533","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"49.7","lymphoid tissue":"30.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"63.0","dendritic cells":"79.8","Hofbauer cells":"90.3","Kupffer cells":"80.9","Langerhans cells":"62.2","Macrophages":"87.0","monocytes":"124.2","Schwann cells":"66.9","T-cells":"47.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"55.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Prostate - T-cells","Skeletal muscle - Macrophages","Stomach - Macrophages","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031833","HPA031834"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031833":"AB_2674063","HPA031834":"AB_10601242"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.44e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.43e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"}},{"Gene":"PASK","Gene synonym":["KIAA0135","PASKIN","STK37"],"Ensembl":"ENSG00000115687","Gene description":"PAS domain containing serine\/threonine kinase","Uniprot":["Q96RG2"],"Chromosome":"2","Position":"241106099-241150264","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"19.8","lymphoid tissue":"22.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Peritubular cells":"23.9","T-cells":"24.9","Theca cells":"23.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"19.8"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016450","HPA021079"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA016450":"AB_1854992","HPA021079":"AB_1854993"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-3"}},{"Gene":"PATJ","Gene synonym":["Cipp","INADL"],"Ensembl":"ENSG00000132849","Gene description":"PATJ crumbs cell polarity complex component","Uniprot":["Q8NI35"],"Chromosome":"1","Position":"61742477-62178675","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"75.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"172.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"75.0"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"7.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 1","Prostate - Prostate basal glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"72.3"},"Antibody":["HPA066352","HPA066960","HPA069079"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Centriolar satellite","Cytosol"],"Antibody RRID":{"HPA066352":"AB_2685663","HPA066960":"AB_2685755","HPA069079":"AB_2686079"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.47e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"}},{"Gene":"PAX6","Gene synonym":["AN","AN1","AN2","D11S812E","WAGR"],"Ensembl":"ENSG00000007372","Gene description":"Paired box 6","Uniprot":["P26367"],"Chromosome":"11","Position":"31784779-31817961","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Disease variant","Peters anomaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"61.6","retina":"68.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Horizontal cells":"481.9","Muller glia cells":"415.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells","Stomach - Gastric enteroendocrine cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"54.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030775","CAB034143"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB034143":"AB_1127044","HPA030775":"AB_10601243"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-3"}},{"Gene":"PBLD","Gene synonym":["FLJ14767","MAWBP","MAWDBP"],"Ensembl":"ENSG00000108187","Gene description":"Phenazine biosynthesis like protein domain containing","Uniprot":["P30039"],"Chromosome":"10","Position":"68282660-68333049","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"171.5","kidney":"270.0","liver":"335.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"210.7","Proximal enterocytes":"363.3","Proximal tubular cells":"330.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"16.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038035","HPA038036"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA038035":"AB_10672470","HPA038036":"AB_10675625"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.44e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"}},{"Gene":"PBOV1","Gene synonym":["UC28","UROC28"],"Ensembl":"ENSG00000254440","Gene description":"Prostate and breast cancer overexpressed 1","Uniprot":["Q9GZY1"],"Chromosome":"6","Position":"138215986-138218491","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"3.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Mucus glandular cells":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063021","HPA069649"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA063021":"AB_2684923","HPA069649":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-4"}},{"Gene":"PBX3","Gene synonym":[],"Ensembl":"ENSG00000167081","Gene description":"PBX homeobox 3","Uniprot":["P40426"],"Chromosome":"9","Position":"125747345-125967377","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"153.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"114.4","Microglial cells":"89.4","Oligodendrocyte precursor cells":"130.4","Oligodendrocytes":"181.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"39.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"plasmacytoid DC":"13.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"13.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"167.4"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"basal ganglia":"46.3","olfactory bulb":"161.9"},"Antibody":["HPA003881"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA003881":"AB_1855020"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"}},{"Gene":"PBXIP1","Gene synonym":["HPIP"],"Ensembl":"ENSG00000163346","Gene description":"PBX homeobox interacting protein 1","Uniprot":["Q96AQ6"],"Chromosome":"1","Position":"154944076-154956123","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"183.4","Muller glia cells":"210.5","Peritubular cells":"128.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"183.9","NK-cells":"56.9","T-cells":"197.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"186.4"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006949","HPA073481"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"26000","Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA006949":"AB_1079572","HPA073481":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.73e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.19e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.99e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.64e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.22e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-3"}},{"Gene":"PCCA","Gene synonym":[],"Ensembl":"ENSG00000175198","Gene description":"Propionyl-CoA carboxylase subunit alpha","Uniprot":["P05165"],"Chromosome":"13","Position":"100089015-100530437","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"218.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"148.0","Distal tubular cells":"121.3","Excitatory neurons":"150.6","Inhibitory neurons":"162.9","Microglial cells":"211.6","Oligodendrocyte precursor cells":"192.1","Oligodendrocytes":"172.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041716","HPA047792"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"290000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA041716":"AB_2677635","HPA047792":"AB_2680156"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"}},{"Gene":"PCCB","Gene synonym":[],"Ensembl":"ENSG00000114054","Gene description":"Propionyl-CoA carboxylase subunit beta","Uniprot":["P05166"],"Chromosome":"3","Position":"136250340-136337896","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Ligase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"202.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"223.8","Late spermatids":"237.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Skin - Sebaceous gland cells","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036939","HPA036940"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036939":"AB_10671366","HPA036940":"AB_10669779"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.47e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"}},{"Gene":"PCDH1","Gene synonym":["pc42"],"Ensembl":"ENSG00000156453","Gene description":"Protocadherin 1","Uniprot":["Q08174"],"Chromosome":"5","Position":"141853090-141879246","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"59.7","Endothelial cells":"42.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"73.8"},"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells","Stomach - Gastric mucous cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047720","HPA050538"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2500000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Cell Junctions"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA047720":"AB_2680130","HPA050538":"AB_2681162"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.96e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.61e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"}},{"Gene":"PCDH10","Gene synonym":["KIAA1400","OL-PCDH"],"Ensembl":"ENSG00000138650","Gene description":"Protocadherin 10","Uniprot":["Q9P2E7"],"Chromosome":"4","Position":"133149294-133208606","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"35.4","placenta":"25.9","prostate":"10.6","seminal vesicle":"17.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"56.3","Endometrial ciliated cells":"33.0","Excitatory neurons":"63.9","Glandular and luminal cells":"32.6","Inhibitory neurons":"56.4","Oligodendrocyte precursor cells":"44.8","Oligodendrocytes":"56.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"8.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Rhabdoid":"42.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011220","HPA073462"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"88000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA011220":"AB_1855041","HPA073462":"AB_2686605"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-4"}},{"Gene":"PCDH11X","Gene synonym":["PCDH-X","PCDH11","PCDHX","PPP1R119"],"Ensembl":"ENSG00000102290","Gene description":"Protocadherin 11 X-linked","Uniprot":["Q9BZA7"],"Chromosome":"X","Position":"91779261-92623230","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"10.7","ovary":"7.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Excitatory neurons":"117.9","Inhibitory neurons":"340.7","Oligodendrocyte precursor cells":"166.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"1.1"},"RNA tissue cell type enrichment":["Adipose visceral - Smooth muscle cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077495"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA077495":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"}},{"Gene":"PCDH11Y","Gene synonym":["PCDH22","PCDHY"],"Ensembl":"ENSG00000099715","Gene description":"Protocadherin 11 Y-linked","Uniprot":["Q9BZA8"],"Chromosome":"Y","Position":"5000226-5742224","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"4.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"51.7","Horizontal cells":"21.1","Inhibitory neurons":"85.8","Microglial cells":"21.0","Oligodendrocyte precursor cells":"52.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"1.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PCDH12","Gene synonym":["VE-cadherin-2"],"Ensembl":"ENSG00000113555","Gene description":"Protocadherin 12","Uniprot":["Q9NPG4"],"Chromosome":"5","Position":"141943581-141969741","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"30.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Adipocytes":"34.8","Endothelial cells":"34.3","Hofbauer cells":"32.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"non-classical monocyte":"4.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"41","RNA blood lineage specific nTPM":{"monocytes":"4.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"3.4"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051242"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051242":"AB_2681402"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.56e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"}},{"Gene":"PCDH15","Gene synonym":["CDHR15","DFNB23","USH1F"],"Ensembl":"ENSG00000150275","Gene description":"Protocadherin related 15","Uniprot":["Q96QU1"],"Chromosome":"10","Position":"53802771-55627942","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adrenal gland":"19.0","brain":"21.2","retina":"61.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"2839.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"6.1"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074437"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"22000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 26: NCI-H716 - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074437":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-3"}},{"Gene":"PCDH17","Gene synonym":["PCDH68","PCH68"],"Ensembl":"ENSG00000118946","Gene description":"Protocadherin 17","Uniprot":["O14917"],"Chromosome":"13","Position":"57631744-57729311","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"27.9","lymphoid tissue":"25.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"58.0","Astrocytes":"74.6","Early spermatids":"76.5","Endothelial cells":"127.1","Excitatory neurons":"123.1","Inhibitory neurons":"66.3","Oligodendrocyte precursor cells":"184.8","Oligodendrocytes":"95.5","Spermatocytes":"59.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"9.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"11.5","Neuroblastoma":"5.7"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Lung - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026817"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"690000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA026817":"AB_1855044"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"}},{"Gene":"PCDH18","Gene synonym":["KIAA1562","PCDH68L"],"Ensembl":"ENSG00000189184","Gene description":"Protocadherin 18","Uniprot":["Q9HCL0"],"Chromosome":"4","Position":"137518918-137532494","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"44.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"68.2","Fibroblasts":"53.1","Leydig cells":"39.2","Peritubular cells":"57.2","Smooth muscle cells":"30.7","Theca cells":"19.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"24.6","testis cancer":"38.3"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Liver - Hepatic stellate cells","Prostate - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017976"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5900000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA017976":"AB_1855045"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.71e-4"}},{"Gene":"PCDH19","Gene synonym":["EFMR","EIEE9","KIAA1313"],"Ensembl":"ENSG00000165194","Gene description":"Protocadherin 19","Uniprot":["Q8TAB3"],"Chromosome":"X","Position":"100291644-100410273","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"21.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"33.2","Excitatory neurons":"24.2","Horizontal cells":"30.1","Inhibitory neurons":"50.5","Oligodendrocyte precursor cells":"39.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"3.6","ovarian cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Esophageal cancer":"3.1"},"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027533"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"83000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027533":"AB_10602043"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"PCDH20","Gene synonym":["FLJ22218","PCDH13"],"Ensembl":"ENSG00000280165","Gene description":"Protocadherin 20","Uniprot":["Q8N6Y1"],"Chromosome":"13","Position":"61409685-61415522","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.0","smooth muscle":"9.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"8.1","Inhibitory neurons":"7.7","Oligodendrocyte precursor cells":"31.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"4.1","Kidney cancer":"4.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Lung - Alveolar cells type 2","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062669"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA062669":"AB_2732687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"PCDH7","Gene synonym":["BH-Pcdh","PPP1R120"],"Ensembl":"ENSG00000169851","Gene description":"Protocadherin 7","Uniprot":["O60245"],"Chromosome":"4","Position":"30720415-31146805","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"50.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"302.1","Excitatory neurons":"1136.1","Inhibitory neurons":"861.3","Oligodendrocyte precursor cells":"878.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"54.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Breast - Breast myoepithelial cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011866","HPA046521"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"340000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA011866":"AB_1855047","HPA046521":"AB_2679682"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.46e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.42e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"}},{"Gene":"PCDH8","Gene synonym":["ARCADLIN","PAPC"],"Ensembl":"ENSG00000136099","Gene description":"Protocadherin 8","Uniprot":["O95206"],"Chromosome":"13","Position":"52842889-52848641","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"20","RNA tissue specific nTPM":{"brain":"28.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"16.2","Excitatory neurons":"24.5","Inhibitory neurons":"18.1","Muller glia cells":"22.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"28.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"4.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010509"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA010509":"AB_10601384"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"PCDH9","Gene synonym":[],"Ensembl":"ENSG00000184226","Gene description":"Protocadherin 9","Uniprot":["Q9HC56"],"Chromosome":"13","Position":"66302834-67230445","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"brain":"159.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"4204.4","Excitatory neurons":"5180.8","Inhibitory neurons":"2437.4","Oligodendrocyte precursor cells":"6046.3","Oligodendrocytes":"13327.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"2.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"4.5","memory B-cell":"5.3","naive B-cell":"17.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"17.3","granulocytes":"4.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"16.6","Rhabdoid":"31.4"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Colon - Enteric glia cells","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015581"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2900000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA015581":"AB_1855048"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-4"}},{"Gene":"PCDHA1","Gene synonym":[],"Ensembl":"ENSG00000204970","Gene description":"Protocadherin alpha 1","Uniprot":["Q9Y5I3"],"Chromosome":"5","Position":"140786136-141012347","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.9","pituitary gland":"1.0","testis":"1.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"1.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"3.9"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035969"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA035969":"AB_10673492"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"}},{"Gene":"PCDHA10","Gene synonym":["CNR8","CNRN8","CNRS8","CRNR8","PCDH-ALPHA10"],"Ensembl":"ENSG00000250120","Gene description":"Protocadherin alpha 10","Uniprot":["Q9Y5I2"],"Chromosome":"5","Position":"140855883-141012347","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.3","pancreas":"4.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"6.0","Early spermatids":"8.4","Exocrine glandular cells":"3.7","Horizontal cells":"5.1","Late spermatids":"3.7","Mucus glandular cells":"5.7","Rod photoreceptor cells":"4.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"8.1"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"}},{"Gene":"PCDHA11","Gene synonym":["CNR7","CNRN7","CNRS7","CRNR7","PCDH-ALPHA11"],"Ensembl":"ENSG00000249158","Gene description":"Protocadherin alpha 11","Uniprot":["Q9Y5I1"],"Chromosome":"5","Position":"140868183-141012347","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.2","parathyroid gland":"2.7","retina":"2.4"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077160"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cell Junctions","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Vesicles","Cell Junctions"],"Subcellular additional location":["Cytoplasmic bodies"],"Antibody RRID":{"HPA077160":"AB_2686827"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"}},{"Gene":"PCDHA12","Gene synonym":["PCDH-ALPHA12"],"Ensembl":"ENSG00000251664","Gene description":"Protocadherin alpha 12","Uniprot":["Q9UN75"],"Chromosome":"5","Position":"140875302-141012347","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"9.0","Bipolar cells":"10.9","Horizontal cells":"8.3","Mucus glandular cells":"7.2","Thymic epithelial cells":"5.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"3.9","cerebral cortex":"1.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035812"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035812":"AB_2674796"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"}},{"Gene":"PCDHA13","Gene synonym":["CNR5","CNRN5","CNRS5","CRNR5","PCDH-ALPHA13"],"Ensembl":"ENSG00000239389","Gene description":"Protocadherin alpha 13","Uniprot":["Q9Y5I0"],"Chromosome":"5","Position":"140882124-141012347","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"4.1","parathyroid gland":"3.5","retina":"1.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"2.0","Cone photoreceptor cells":"1.7","Early spermatids":"1.2","Horizontal cells":"3.2","Rod photoreceptor cells":"1.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"4.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"3.8"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"PCDHA2","Gene synonym":[],"Ensembl":"ENSG00000204969","Gene description":"Protocadherin alpha 2","Uniprot":["Q9Y5H9"],"Chromosome":"5","Position":"140794852-141012347","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.8","pituitary gland":"1.8"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"3.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035653"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035653":"AB_10670969"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-6"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"}},{"Gene":"PCDHA3","Gene synonym":["PCDH-ALPHA3"],"Ensembl":"ENSG00000255408","Gene description":"Protocadherin alpha 3","Uniprot":["Q9Y5H8"],"Chromosome":"5","Position":"140801028-141012347","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"3.0","Neuroblastoma":"3.5"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"}},{"Gene":"PCDHA4","Gene synonym":["CNR1","CNRN1","CRNR1","PCDH-ALPHA4"],"Ensembl":"ENSG00000204967","Gene description":"Protocadherin alpha 4","Uniprot":["Q9UN74"],"Chromosome":"5","Position":"140806929-141012347","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.5","Early spermatids":"1.3","Horizontal cells":"1.3","Pancreatic endocrine cells":"1.7","Rod photoreceptor cells":"1.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"5.7"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043180","HPA073478"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA043180":"AB_10806381","HPA073478":"AB_2686608"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"}},{"Gene":"PCDHA5","Gene synonym":["CNR6","CNRN6","CNRS6","CRNR6","PCDH-ALPHA5"],"Ensembl":"ENSG00000204965","Gene description":"Protocadherin alpha 5","Uniprot":["Q9Y5H7"],"Chromosome":"5","Position":"140821604-141012347","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"3.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.1","Horizontal cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"3.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"1.6"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044557"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Plasma membrane","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles","Mitochondria"],"Antibody RRID":{"HPA044557":"AB_10970597"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"}},{"Gene":"PCDHA6","Gene synonym":["CNR2","CNRS2","CRNR2","PCDH-ALPHA6"],"Ensembl":"ENSG00000081842","Gene description":"Protocadherin alpha 6","Uniprot":["Q9UN73"],"Chromosome":"5","Position":"140827958-141012347","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"4.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059326","HPA078110"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059326":"AB_2683980","HPA078110":"AB_2732371"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"}},{"Gene":"PCDHA7","Gene synonym":["CNR4","CNRS4","CRNR4"],"Ensembl":"ENSG00000204963","Gene description":"Protocadherin alpha 7","Uniprot":["Q9UN72"],"Chromosome":"5","Position":"140834248-141012347","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"1.9","Early spermatids":"1.1","Horizontal cells":"1.9","Melanocytes":"1.7","Respiratory ciliated cells":"1.4","Spermatocytes":"1.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"3.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 20: Airway & Pancreas - Proteolysis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"}},{"Gene":"PCDHA8","Gene synonym":[],"Ensembl":"ENSG00000204962","Gene description":"Protocadherin alpha 8","Uniprot":["Q9Y5H6"],"Chromosome":"5","Position":"140841187-141012347","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"3.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"3.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"1.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044585"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044585":"AB_10793953"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"PCDHA9","Gene synonym":["KIAA0345","PCDH-ALPHA9"],"Ensembl":"ENSG00000204961","Gene description":"Protocadherin alpha 9","Uniprot":["Q9Y5H5"],"Chromosome":"5","Position":"140847772-141012347","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.2","testis":"1.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"2.2","Cone photoreceptor cells":"3.4","Early spermatids":"2.2","Horizontal cells":"1.9","Rod photoreceptor cells":"1.2","Spermatocytes":"2.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"3.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"PCDHAC1","Gene synonym":[],"Ensembl":"ENSG00000248383","Gene description":"Protocadherin alpha subfamily C, 1","Uniprot":["Q9H158"],"Chromosome":"5","Position":"140926299-141012347","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"parathyroid gland":"29.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"2.2","Alveolar cells type 2":"3.0","Bipolar cells":"1.5","Collecting duct cells":"2.0","Cone photoreceptor cells":"1.7","Rod photoreceptor cells":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"3.3"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052775"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA052775":"AB_2681942"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"}},{"Gene":"PCDHAC2","Gene synonym":["PCDH-ALPHA-C2"],"Ensembl":"ENSG00000243232","Gene description":"Protocadherin alpha subfamily C, 2","Uniprot":["Q9Y5I4"],"Chromosome":"5","Position":"140966470-141012347","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"16.9","parathyroid gland":"42.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"1.7","Alveolar cells type 2":"1.7","Collecting duct cells":"2.0","Cone photoreceptor cells":"1.7","Horizontal cells":"1.3","Rod photoreceptor cells":"1.2","Sertoli cells":"2.8","Thymic epithelial cells":"5.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"5.8"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076190"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA076190":"AB_2686785"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"}},{"Gene":"PCDHB1","Gene synonym":["PCDH-BETA1"],"Ensembl":"ENSG00000171815","Gene description":"Protocadherin beta 1","Uniprot":["Q9Y5F3"],"Chromosome":"5","Position":"141051374-141059346","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"1.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Respiratory ciliated cells":"1.4","Skeletal myocytes":"2.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053921"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA053921":"AB_2682310"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-4"}},{"Gene":"PCDHB10","Gene synonym":[],"Ensembl":"ENSG00000120324","Gene description":"Protocadherin beta 10","Uniprot":["Q9UN67"],"Chromosome":"5","Position":"141192353-141195647","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"2.7","Bipolar cells":"6.5","Endometrial stromal cells":"3.3","Endothelial cells":"2.5","Peritubular cells":"3.2","Sertoli cells":"5.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"4.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"9.8"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013445"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013445":"AB_1855054"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"}},{"Gene":"PCDHB11","Gene synonym":["ME2","PCDH-BETA11"],"Ensembl":"ENSG00000197479","Gene description":"Protocadherin beta 11","Uniprot":["Q9Y5F2"],"Chromosome":"5","Position":"141199610-141203779","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"3.3","Endometrial stromal cells":"3.3","Fibroblasts":"4.0","Leydig cells":"2.4","Peritubular cells":"2.8","Sertoli cells":"2.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045042"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA045042":"AB_2679194"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"}},{"Gene":"PCDHB12","Gene synonym":["PCDH-BETA12"],"Ensembl":"ENSG00000120328","Gene description":"Protocadherin beta 12","Uniprot":["Q9Y5F1"],"Chromosome":"5","Position":"141208697-141212571","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"1.9","Bipolar cells":"4.3","Endometrial stromal cells":"2.6","Fibroblasts":"2.4","Melanocytes":"1.7","Mucus glandular cells":"1.8","Peritubular cells":"2.0","Skeletal myocytes":"2.0","Smooth muscle cells":"1.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"3.1"},"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045042"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA045042":"AB_2679194"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-3"}},{"Gene":"PCDHB13","Gene synonym":["PCDH-BETA13"],"Ensembl":"ENSG00000187372","Gene description":"Protocadherin beta 13","Uniprot":["Q9Y5F0"],"Chromosome":"5","Position":"141213919-141218979","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"3.8","Horizontal cells":"3.2","Melanocytes":"3.5","Mucus glandular cells":"6.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-3"}},{"Gene":"PCDHB14","Gene synonym":["PCDH-BETA14"],"Ensembl":"ENSG00000120327","Gene description":"Protocadherin beta 14","Uniprot":["Q9Y5E9"],"Chromosome":"5","Position":"141223343-141227759","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"9.2","Early spermatids":"10.8","Peritubular cells":"7.7","Skeletal myocytes":"7.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"10.2"},"RNA tissue cell type enrichment":["Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007692","HPA045248"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"39000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA007692":"AB_2667896","HPA045248":"AB_10959599"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"}},{"Gene":"PCDHB15","Gene synonym":["PCDH-BETA15"],"Ensembl":"ENSG00000113248","Gene description":"Protocadherin beta 15","Uniprot":["Q9Y5E8"],"Chromosome":"5","Position":"141245395-141249365","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"4.0","Bipolar cells":"4.4","Early spermatids":"7.5","Endometrial stromal cells":"3.9","Fibroblasts":"3.8","Horizontal cells":"3.8","Melanocytes":"3.5","Peritubular cells":"3.2","Smooth muscle cells":"3.3","Spermatocytes":"3.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"4.4"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007172","CAB026471","HPA074676"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"250000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB026471":null,"HPA007172":"AB_1079576","HPA074676":"AB_2732263"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"}},{"Gene":"PCDHB16","Gene synonym":["KIAA1621","ME1","PCDH-BETA16","PCDH3X","PCDHB8a"],"Ensembl":"ENSG00000272674","Gene description":"Protocadherin beta 16","Uniprot":["Q9NRJ7"],"Chromosome":"5","Position":"141182387-141186226","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"8.3","Cholangiocytes":"7.7","Endometrial stromal cells":"8.4","Fibroblasts":"6.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Fibroblasts","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014668"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014668":"AB_1855055"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-3"}},{"Gene":"PCDHB2","Gene synonym":["PCDH-BETA2"],"Ensembl":"ENSG00000112852","Gene description":"Protocadherin beta 2","Uniprot":["Q9Y5E7"],"Chromosome":"5","Position":"141094606-141098703","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"6.9","Melanocytes":"5.2","Spermatocytes":"9.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007548"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA007548":"AB_2667859"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.84e-4"}},{"Gene":"PCDHB3","Gene synonym":["PCDH-BETA3"],"Ensembl":"ENSG00000113205","Gene description":"Protocadherin beta 3","Uniprot":["Q9Y5E6"],"Chromosome":"5","Position":"141100473-141103827","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"2.9","Endometrial stromal cells":"2.6","Fibroblasts":"1.6","Horizontal cells":"3.2","Sertoli cells":"2.8","Spermatocytes":"1.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050296"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA050296":"AB_2681078"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-4"}},{"Gene":"PCDHB4","Gene synonym":["PCDH-BETA4"],"Ensembl":"ENSG00000081818","Gene description":"Protocadherin beta 4","Uniprot":["Q9Y5E5"],"Chromosome":"5","Position":"141121818-141125623","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"8.8","Endometrial stromal cells":"8.3","Fibroblasts":"9.3","Horizontal cells":"6.4","Peritubular cells":"6.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"3.3"},"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014466"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"HPA014466":"AB_1855058"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"}},{"Gene":"PCDHB5","Gene synonym":["DKFZp586B0217","PCDH-BETA5"],"Ensembl":"ENSG00000113209","Gene description":"Protocadherin beta 5","Uniprot":["Q9Y5E4"],"Chromosome":"5","Position":"141135206-141138615","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"10.7","Exocrine glandular cells":"5.5","Pancreatic endocrine cells":"5.2","Prostatic glandular cells":"5.5","Schwann cells":"4.9","Spermatocytes":"10.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"21.7"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013191","HPA067473"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA013191":"AB_1855059","HPA067473":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"}},{"Gene":"PCDHB6","Gene synonym":["PCDH-BETA6"],"Ensembl":"ENSG00000113211","Gene description":"Protocadherin beta 6","Uniprot":["Q9Y5E3"],"Chromosome":"5","Position":"141150057-141153287","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.4","Early spermatids":"1.4","Sertoli cells":"2.8","Spermatocytes":"5.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029566","HPA075308"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA029566":"AB_10601385","HPA075308":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.52e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"}},{"Gene":"PCDHB7","Gene synonym":["PCDH-BETA7"],"Ensembl":"ENSG00000113212","Gene description":"Protocadherin beta 7","Uniprot":["Q9Y5E2"],"Chromosome":"5","Position":"141172644-141176383","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"40.8","Late spermatids":"29.5","Spermatocytes":"20.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"5.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"4.3"},"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Prostate - Fibroblasts","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059271"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059271":"AB_2683962"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-4"}},{"Gene":"PCDHB8","Gene synonym":["PCDH-BETA8","PCDH3I"],"Ensembl":"ENSG00000120322","Gene description":"Protocadherin beta 8","Uniprot":["Q9UN66"],"Chromosome":"5","Position":"141177790-141180539","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"6.4","Spermatocytes":"5.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057773"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057773":"AB_2683525"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-4"}},{"Gene":"PCDHB9","Gene synonym":["PCDH-BETA9","PCDH3H"],"Ensembl":"ENSG00000177839","Gene description":"Protocadherin beta 9","Uniprot":["Q9Y5E1"],"Chromosome":"5","Position":"141187127-141191541","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Bipolar cells":"17.3","Horizontal cells":"12.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"4.6"},"RNA tissue cell type enrichment":["Lung - Fibroblast_1","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013445"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013445":"AB_1855054"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"}},{"Gene":"PCDHGA1","Gene synonym":["PCDH-GAMMA-A1"],"Ensembl":"ENSG00000204956","Gene description":"Protocadherin gamma subfamily A, 1","Uniprot":["Q9Y5H4"],"Chromosome":"5","Position":"141330571-141512981","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"2.4","Cardiomyocytes":"1.3","Horizontal cells":"1.3","Melanocytes":"1.7","Skeletal myocytes":"6.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580","HPA036547"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401","HPA036547":"AB_10669798"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"}},{"Gene":"PCDHGA10","Gene synonym":["PCDH-GAMMA-A10"],"Ensembl":"ENSG00000253846","Gene description":"Protocadherin gamma subfamily A, 10","Uniprot":["Q9Y5H3"],"Chromosome":"5","Position":"141412987-141512979","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"24.3","Horizontal cells":"15.4","Skeletal myocytes":"67.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580","HPA077276"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Vesicles","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401","HPA077276":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"}},{"Gene":"PCDHGA11","Gene synonym":["PCDH-GAMMA-A11"],"Ensembl":"ENSG00000253873","Gene description":"Protocadherin gamma subfamily A, 11","Uniprot":["Q9Y5H2"],"Chromosome":"5","Position":"141421047-141512975","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"3.1","Skeletal myocytes":"8.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"9.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Vesicles","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"}},{"Gene":"PCDHGA12","Gene synonym":["CDH21","FIB3","KIAA0588","PCDH-GAMMA-A12"],"Ensembl":"ENSG00000253159","Gene description":"Protocadherin gamma subfamily A, 12","Uniprot":["O60330"],"Chromosome":"5","Position":"141430507-141512975","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"5.0","Endometrial stromal cells":"2.3","Fibroblasts":"3.2","Skeletal myocytes":"10.9","Thymic epithelial cells":"3.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"1.7","melanoma":"5.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"1.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"1.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"3.1","skin cancer":"6.0"},"RNA tissue cell type enrichment":["Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-3"}},{"Gene":"PCDHGA2","Gene synonym":["PCDH-GAMMA-A2"],"Ensembl":"ENSG00000081853","Gene description":"Protocadherin gamma subfamily A, 2","Uniprot":["Q9Y5H1"],"Chromosome":"5","Position":"141338760-141512975","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"2.0","Fibroblasts":"2.2","Peritubular cells":"1.6","Schwann cells":"4.4","Skeletal myocytes":"3.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580","HPA038625"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Vesicles","Plasma membrane","Focal adhesion sites","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Nucleoli","Focal adhesion sites","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401","HPA038625":"AB_2732480"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-4"}},{"Gene":"PCDHGA3","Gene synonym":["PCDH-GAMMA-A3"],"Ensembl":"ENSG00000254245","Gene description":"Protocadherin gamma subfamily A, 3","Uniprot":["Q9Y5H0"],"Chromosome":"5","Position":"141343829-141512975","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"2.1","Fibroblasts":"2.0","Horizontal cells":"1.9","Schwann cells":"5.5","Skeletal myocytes":"8.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-4"}},{"Gene":"PCDHGA4","Gene synonym":["PCDH-GAMMA-A4"],"Ensembl":"ENSG00000262576","Gene description":"Protocadherin gamma subfamily A, 4","Uniprot":["Q9Y5G9"],"Chromosome":"5","Position":"141355021-141512975","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Skeletal myocytes":"4.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-4"}},{"Gene":"PCDHGA5","Gene synonym":["CDH-GAMMA-A5","ME3","PCDH-GAMMA-A5"],"Ensembl":"ENSG00000253485","Gene description":"Protocadherin gamma subfamily A, 5","Uniprot":["Q9Y5G8"],"Chromosome":"5","Position":"141364232-141512979","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"11.8","Endometrial stromal cells":"8.9","Skeletal myocytes":"31.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Fibroblast_1","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-4"}},{"Gene":"PCDHGA6","Gene synonym":["PCDH-GAMMA-A6"],"Ensembl":"ENSG00000253731","Gene description":"Protocadherin gamma subfamily A, 6","Uniprot":["Q9Y5G7"],"Chromosome":"5","Position":"141373891-141512975","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"7.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"11.6","Skeletal myocytes":"26.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"}},{"Gene":"PCDHGA7","Gene synonym":["PCDH-GAMMA-A7"],"Ensembl":"ENSG00000253537","Gene description":"Protocadherin gamma subfamily A, 7","Uniprot":["Q9Y5G6"],"Chromosome":"5","Position":"141382739-141512975","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"4.2","Endometrial stromal cells":"2.1","Mucus glandular cells":"1.7","Prostatic glandular cells":"2.4","Skeletal myocytes":"8.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"}},{"Gene":"PCDHGA8","Gene synonym":["KIAA0327","PCDH-GAMMA-A8"],"Ensembl":"ENSG00000253767","Gene description":"Protocadherin gamma subfamily A, 8","Uniprot":["Q9Y5G5"],"Chromosome":"5","Position":"141390157-141512975","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"3.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"7.9","Horizontal cells":"5.1","Salivary duct cells":"4.0","Skeletal myocytes":"21.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"}},{"Gene":"PCDHGA9","Gene synonym":["PCDH-GAMMA-A9"],"Ensembl":"ENSG00000261934","Gene description":"Protocadherin gamma subfamily A, 9","Uniprot":["Q9Y5G4"],"Chromosome":"5","Position":"141402932-141512979","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"3.7","Cardiomyocytes":"2.3","Horizontal cells":"2.6","Mucus glandular cells":"1.8","Skeletal myocytes":"7.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"}},{"Gene":"PCDHGB1","Gene synonym":["PCDH-GAMMA-B1"],"Ensembl":"ENSG00000254221","Gene description":"Protocadherin gamma subfamily B, 1","Uniprot":["Q9Y5G3"],"Chromosome":"5","Position":"141350102-141512979","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"4.3","Late spermatids":"8.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"7.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580","HPA076182"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Focal adhesion sites","Midbody"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Focal adhesion sites","Midbody"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401","HPA076182":"AB_2686783"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-3"}},{"Gene":"PCDHGB2","Gene synonym":["PCDH-GAMMA-B2"],"Ensembl":"ENSG00000253910","Gene description":"Protocadherin gamma subfamily B, 2","Uniprot":["Q9Y5G2"],"Chromosome":"5","Position":"141360042-141512979","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.4","Cardiomyocytes":"2.0","Mucus glandular cells":"1.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"6.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580","HPA077526"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Vesicles","Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401","HPA077526":"AB_2732350"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.67e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-4"}},{"Gene":"PCDHGB3","Gene synonym":["PCDH-GAMMA-B3"],"Ensembl":"ENSG00000262209","Gene description":"Protocadherin gamma subfamily B, 3","Uniprot":["Q9Y5G1"],"Chromosome":"5","Position":"141370242-141512975","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Salivary duct cells":"1.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Fibroblast_1"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580","HPA035822","HPA035823"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Vesicles","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401","HPA035822":null,"HPA035823":"AB_2674802"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"}},{"Gene":"PCDHGB4","Gene synonym":["CDH20","FIB2","PCDH-GAMMA-B4"],"Ensembl":"ENSG00000253953","Gene description":"Protocadherin gamma subfamily B, 4","Uniprot":["Q9UN71"],"Chromosome":"5","Position":"141387698-141512975","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"15.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"}},{"Gene":"PCDHGB5","Gene synonym":["PCDH-GAMMA-B5"],"Ensembl":"ENSG00000276547","Gene description":"Protocadherin gamma subfamily B, 5","Uniprot":["Q9Y5G0"],"Chromosome":"5","Position":"141397987-141512979","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"20.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.6","Mucus glandular cells":"1.9","Prostatic glandular cells":"1.2","Salivary duct cells":"1.1","Skeletal myocytes":"3.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-4"}},{"Gene":"PCDHGB6","Gene synonym":["PCDH-GAMMA-B6"],"Ensembl":"ENSG00000253305","Gene description":"Protocadherin gamma subfamily B, 6","Uniprot":["Q9Y5F9"],"Chromosome":"5","Position":"141408021-141512979","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Mucus glandular cells":"8.3","Skeletal myocytes":"16.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-4"}},{"Gene":"PCDHGB7","Gene synonym":["ME6","PCDH-GAMMA-B7"],"Ensembl":"ENSG00000254122","Gene description":"Protocadherin gamma subfamily B, 7","Uniprot":["Q9Y5F8"],"Chromosome":"5","Position":"141417645-141512975","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"7.4","Fibroblasts":"3.9","Horizontal cells":"3.8","Mucus glandular cells":"3.5","Schwann cells":"5.6","Skeletal myocytes":"8.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"7.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"13.5","Rhabdoid":"15.8"},"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"}},{"Gene":"PCDHGC3","Gene synonym":["PC-43","PC43","PCDH-GAMMA-C3","PCDH2"],"Ensembl":"ENSG00000240184","Gene description":"Protocadherin gamma subfamily C, 3","Uniprot":["Q9UN70"],"Chromosome":"5","Position":"141475947-141512977","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"308.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"6.3","Bipolar cells":"7.6","Fibroblasts":"11.8","Serous glandular cells":"8.6","Skeletal myocytes":"7.9","Thymic epithelial cells":"11.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"55.0","melanoma":"20.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"24","RNA blood cell specific nTPM":{"plasmacytoid DC":"15.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"24","RNA blood lineage specific nTPM":{"dendritic cells":"15.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Lung - Fibroblast_1","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580","HPA077289"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401","HPA077289":"AB_2686832"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.19e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.00e-4"}},{"Gene":"PCDHGC4","Gene synonym":["PCDH-GAMMA-C4"],"Ensembl":"ENSG00000242419","Gene description":"Protocadherin gamma subfamily C, 4","Uniprot":["Q9Y5F7"],"Chromosome":"5","Position":"141484997-141512979","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"31.4"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"glioma":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"3.3","testis cancer":"10.0"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"}},{"Gene":"PCDHGC5","Gene synonym":["PCDH-GAMMA-C5"],"Ensembl":"ENSG00000240764","Gene description":"Protocadherin gamma subfamily C, 5","Uniprot":["Q9Y5F6"],"Chromosome":"5","Position":"141489081-141512975","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"28.4"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"glioma":"3.1","head and neck cancer":"0.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"28.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"4.7","testis cancer":"7.4"},"RNA tissue cell type enrichment":["Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008755","HPA010580","HPA076140"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":null,"Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA008755":"AB_1079577","HPA010580":"AB_2732401","HPA076140":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"}},{"Gene":"PCGF3","Gene synonym":["DONG1","FLJ36550","MGC40413","RNF3","RNF3A"],"Ensembl":"ENSG00000185619","Gene description":"Polycomb group ring finger 3","Uniprot":["Q3KNV8"],"Chromosome":"4","Position":"705748-770640","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061879"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA061879":"AB_2684631"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.73e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.44e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-4"}},{"Gene":"PCID2","Gene synonym":["FLJ11305"],"Ensembl":"ENSG00000126226","Gene description":"PCI domain containing 2","Uniprot":["Q5JVF3"],"Chromosome":"13","Position":"113177536-113208715","Protein class":["Predicted intracellular proteins"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"191.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069107","HPA073074"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA069107":"AB_2686088","HPA073074":"AB_2686568"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.80e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"}},{"Gene":"PCLO","Gene synonym":["ACZ","DKFZp779G1236","KIAA0559"],"Ensembl":"ENSG00000186472","Gene description":"Piccolo presynaptic cytomatrix protein","Uniprot":["Q9Y6V0"],"Chromosome":"7","Position":"82754012-83162930","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"25.6","pituitary gland":"11.1","retina":"21.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"645.6","Horizontal cells":"176.2","Inhibitory neurons":"729.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"25.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"16.6"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Lung - Alveolar cells type 2","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015858","HPA029579","CAB079012"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"CAB079012":null,"HPA015858":"AB_1855071","HPA029579":"AB_10602044"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-5"}},{"Gene":"PCMT1","Gene synonym":[],"Ensembl":"ENSG00000120265","Gene description":"Protein-L-isoaspartate (D-aspartate) O-methyltransferase","Uniprot":["P22061"],"Chromosome":"6","Position":"149749443-149811420","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"659.3","Late spermatids":"741.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003239"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4100000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA003239":"AB_1079580"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.02e-7"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.58e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.27e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.88e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.38e-4"}},{"Gene":"PCNT","Gene synonym":["KEN","KIAA0402","PCN","PCNT2","PCNTB","SCKL4"],"Ensembl":"ENSG00000160299","Gene description":"Pericentrin","Uniprot":["O95613"],"Chromosome":"21","Position":"46324141-46445769","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding"],"Disease involvement":["Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"239.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Skeletal myocytes":"378.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"4.6","granulocytes":"6.0","T-cells":"8.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016820","HPA019887","HPA032101"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centriolar satellite","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Centrosome"],"Subcellular additional location":["Centriolar satellite","Cytosol"],"Antibody RRID":{"HPA016820":"AB_1855079","HPA019887":"AB_1855080","HPA032101":"AB_2674151"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"}},{"Gene":"PCNX1","Gene synonym":["KIAA0805","KIAA0995","PCNX","PCNXL1","pecanex"],"Ensembl":"ENSG00000100731","Gene description":"Pecanex 1","Uniprot":["Q96RV3"],"Chromosome":"14","Position":"70907405-71115382","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"161.2","Inhibitory neurons":"152.4","Oligodendrocyte precursor cells":"141.5","Oligodendrocytes":"125.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048970","HPA053532"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA048970":null,"HPA053532":"AB_2682180"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.05e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"}},{"Gene":"PCNX2","Gene synonym":["FLJ11383","KIAA0435","PCNXL2"],"Ensembl":"ENSG00000135749","Gene description":"Pecanex 2","Uniprot":["A6NKB5"],"Chromosome":"1","Position":"232983435-233295725","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"258.6","Inhibitory neurons":"230.3","Microglial cells":"134.1","Oligodendrocyte precursor cells":"130.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013815","HPA014427"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA013815":"AB_2236561","HPA014427":"AB_1855081"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.27e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"}},{"Gene":"PCNX3","Gene synonym":["FLJ22427","PCNXL3"],"Ensembl":"ENSG00000197136","Gene description":"Pecanex 3","Uniprot":["Q9H6A9"],"Chromosome":"11","Position":"65615773-65637439","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018084"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA018084":"AB_1855083"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-1"}},{"Gene":"PCNX4","Gene synonym":["C14orf135","PCNXL4"],"Ensembl":"ENSG00000126773","Gene description":"Pecanex 4","Uniprot":["Q63HM2"],"Chromosome":"14","Position":"60091911-60169133","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002076","HPA003390"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002076":"AB_1078322","HPA003390":"AB_2066703"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.84e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"}},{"Gene":"PCSK4","Gene synonym":["DKFZp434B217","MGC34749","PC4","SPC5"],"Ensembl":"ENSG00000115257","Gene description":"Proprotein convertase subtilisin\/kexin type 4","Uniprot":["Q6UW60"],"Chromosome":"19","Position":"1481428-1490752","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"testis":"66.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"237.1","Late spermatids":"674.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005572"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA005572":"AB_1855087"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.45e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"}},{"Gene":"PCSK5","Gene synonym":["PC5","PC6","SPC6"],"Ensembl":"ENSG00000099139","Gene description":"Proprotein convertase subtilisin\/kexin type 5","Uniprot":["Q92824"],"Chromosome":"9","Position":"75890644-76362975","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Pregnancy"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"183.8","Inhibitory neurons":"79.5","Oligodendrocyte precursor cells":"143.0","Proximal enterocytes":"151.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"2447.1","neutrophil":"626.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"granulocytes":"2447.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031072"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"290000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA031072":"AB_10602190"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.61e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-5"}},{"Gene":"PCSK6","Gene synonym":["PACE4","SPC4"],"Ensembl":"ENSG00000140479","Gene description":"Proprotein convertase subtilisin\/kexin type 6","Uniprot":["P29122"],"Chromosome":"15","Position":"101289784-101525202","Protein class":["Enzymes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"153.6","liver":"160.0","lymphoid tissue":"81.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"189.1","Oligodendrocytes":"530.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"8.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"3.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Liver - Hepatocytes","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004774"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"480000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004774":"AB_1079583"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.99e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.06e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"}},{"Gene":"PCSK7","Gene synonym":["LPC","PC7","PC8","SPC7"],"Ensembl":"ENSG00000160613","Gene description":"Proprotein convertase subtilisin\/kexin type 7","Uniprot":["Q16549"],"Chromosome":"11","Position":"117204337-117232525","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"226.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Stomach - Macrophages","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8400","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"}},{"Gene":"PDCD1","Gene synonym":["CD279","hSLE1","PD-1","PD1","SLEB2"],"Ensembl":"ENSG00000188389","Gene description":"Programmed cell death 1","Uniprot":["Q15116"],"Chromosome":"2","Position":"241849884-241858894","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Apoptosis","Immunity"],"Molecular function":null,"Disease involvement":["FDA approved drug targets","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"6.7","lymphoid tissue":"16.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Schwann cells":"8.3","T-cells":"30.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"1.4"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"4.4","MAIT T-cell":"4.8","memory CD4 T-cell":"8.7","memory CD8 T-cell":"12.4","T-reg":"4.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"55","RNA blood lineage specific nTPM":{"T-cells":"12.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"1.0","lymphoma":"1.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Colon - T-cells","Liver - T-cells","Prostate - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035981","CAB038418","CAB076386"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB038418":"AB_1160824","CAB076386":"AB_881954","HPA035981":"AB_10669664"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.44e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.48e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"}},{"Gene":"PDCD1LG2","Gene synonym":["B7-DC","bA574F11.2","Btdc","CD273","PD-L2","PDL2"],"Ensembl":"ENSG00000197646","Gene description":"Programmed cell death 1 ligand 2","Uniprot":["Q9BQ51"],"Chromosome":"9","Position":"5510531-5571282","Protein class":["Cancer-related genes","CD markers","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"15.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"21.9","Fibroblasts":"7.3","granulocytes":"12.6","Langerhans cells":"14.1","Leydig cells":"6.9","Microglial cells":"11.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Kidney - Endothelial cells","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013411"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"31000000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA013411":"AB_1855102"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.15e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-3"}},{"Gene":"PDCD6","Gene synonym":["ALG-2","PEF1B"],"Ensembl":"ENSG00000249915","Gene description":"Programmed cell death 6","Uniprot":["O75340"],"Chromosome":"5","Position":"271621-314974","Protein class":["Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":["Angiogenesis","Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"73.4","Ductal cells":"93.1","Proximal enterocytes":"78.1","Undifferentiated cells":"76.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047221"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA047221":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.47e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.16e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.19e-4"}},{"Gene":"PDE3A","Gene synonym":["CGI-PDE"],"Ensembl":"ENSG00000172572","Gene description":"Phosphodiesterase 3A","Uniprot":["Q14432"],"Chromosome":"12","Position":"20368537-20688583","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"43.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"95.2","Bipolar cells":"80.4","Cardiomyocytes":"212.4","Horizontal cells":"97.4","Inhibitory neurons":"76.7","Smooth muscle cells":"66.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"15.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Breast - Endothelial cells","Kidney - Fibroblasts","Prostate - Smooth muscle cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"18.8"},"Antibody":["HPA014492","HPA074258"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"37000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014492":"AB_1855120","HPA074258":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-4"}},{"Gene":"PDE3B","Gene synonym":["HcGIP1"],"Ensembl":"ENSG00000152270","Gene description":"Phosphodiesterase 3B","Uniprot":["Q13370"],"Chromosome":"11","Position":"14643804-14872044","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis"],"Molecular function":["Hydrolase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"64.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"166.4","Excitatory neurons":"138.4","Inhibitory neurons":"154.4","Microglial cells":"187.0","Oligodendrocyte precursor cells":"113.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"13.5"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"3.8","T-cells":"6.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056111"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA056111":"AB_2683041"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.91e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-3"}},{"Gene":"PDGFRA","Gene synonym":["CD140a","GAS9","PDGFR2"],"Ensembl":"ENSG00000134853","Gene description":"Platelet derived growth factor receptor alpha","Uniprot":["P16234"],"Chromosome":"4","Position":"54229280-54298245","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Chemotaxis","Host-virus interaction"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"190.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Endometrial stromal cells":"374.7","Fibroblasts":"250.2","Leydig cells":"430.4","Oligodendrocyte precursor cells":"478.5","Peritubular cells":"384.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"30.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"76.7","thyroid cancer":"37.7"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004947","CAB018143"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"300000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB018143":"AB_2162351","HPA004947":"AB_2732399"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.33e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.79e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"}},{"Gene":"PDGFRB","Gene synonym":["CD140b","JTK12","PDGFR","PDGFR1"],"Ensembl":"ENSG00000113721","Gene description":"Platelet derived growth factor receptor beta","Uniprot":["P09619"],"Chromosome":"5","Position":"150113839-150155872","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Chemotaxis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"139.1","Leydig cells":"161.7","Peritubular cells":"206.1","Sertoli cells":"522.4","Smooth muscle cells":"274.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"30.9","testis cancer":"38.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Kidney - Fibroblasts","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003842","CAB018144","HPA028499"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"39000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB003842":"AB_562328","CAB018144":"AB_2162497","HPA028499":"AB_10602018"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.87e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.11e-4"}},{"Gene":"PDIA6","Gene synonym":["ERp5","P5","TXNDC7"],"Ensembl":"ENSG00000143870","Gene description":"Protein disulfide isomerase family A member 6","Uniprot":["Q15084"],"Chromosome":"2","Position":"10783391-10837977","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone","Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"1344.5","Plasma cells":"955.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Macrophages","Heart muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034347","HPA034652","HPA034653"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034347":"AB_2299360","HPA034652":"AB_2674263","HPA034653":"AB_10601982"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.80e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.63e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.51e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"}},{"Gene":"PDIK1L","Gene synonym":["CLIK1L"],"Ensembl":"ENSG00000175087","Gene description":"PDLIM1 interacting kinase 1 like","Uniprot":["Q8N165"],"Chromosome":"1","Position":"26111165-26125555","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064157"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA064157":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"}},{"Gene":"PDK1","Gene synonym":[],"Ensembl":"ENSG00000152256","Gene description":"Pyruvate dehydrogenase kinase 1","Uniprot":["Q15118"],"Chromosome":"2","Position":"172555373-172608669","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"135.0","Plasma cells":"141.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"8.6","granulocytes":"25.2","T-cells":"21.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"60.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017554","HPA027376"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 34: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB017554":"AB_2161138","HPA027376":"AB_1855139"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.30e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.10e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"}},{"Gene":"PDLIM5","Gene synonym":["Enh","LIM"],"Ensembl":"ENSG00000163110","Gene description":"PDZ and LIM domain 5","Uniprot":["Q96HC4"],"Chromosome":"4","Position":"94451857-94668227","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"heart muscle":"629.5","skeletal muscle":"1163.5","tongue":"576.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"2678.8","Skeletal myocytes":"869.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"prostate cancer":"132.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"219.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"219.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013511","HPA016740","HPA020026"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Focal adhesion sites"],"Antibody RRID":{"CAB013511":"AB_2533388","HPA016740":"AB_1855153","HPA020026":"AB_1855154"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"PDPN","Gene synonym":["aggrus","Gp38","GP40","PA2.26","T1A-2"],"Ensembl":"ENSG00000162493","Gene description":"Podoplanin","Uniprot":["Q86YL7"],"Chromosome":"1","Position":"13583465-13617957","Protein class":["Predicted membrane proteins"],"Biological process":["Cell shape"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"135.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"93.0","Basal respiratory cells":"93.9","Muller glia cells":"80.7","Peritubular cells":"65.7","Thymic epithelial cells":"324.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"83.2","head and neck cancer":"40.2","testis cancer":"102.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"119.0","thyroid cancer":"95.0"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Kidney - Podocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007534","HPA007949","CAB008376"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions","Mitochondria"],"Antibody RRID":{"CAB008376":"AB_592530","HPA007534":"AB_1857718","HPA007949":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"}},{"Gene":"PDZK1IP1","Gene synonym":["DD96","MAP17","SPAP"],"Ensembl":"ENSG00000162366","Gene description":"PDZK1 interacting protein 1","Uniprot":["Q13113"],"Chromosome":"1","Position":"47183582-47191044","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"kidney":"1047.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal tubular cells":"4841.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"340.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"6.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"540.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enterocytes","Kidney - Proximal tubular cells","Lung - Alveolar cells type 2","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014907"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA014907":"AB_1855166"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.92e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.45e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"}},{"Gene":"PEAR1","Gene synonym":["FLJ00193","JEDI","MEGF12"],"Ensembl":"ENSG00000187800","Gene description":"Platelet endothelial aggregation receptor 1","Uniprot":["Q5VY43"],"Chromosome":"1","Position":"156893698-156916434","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"42.1","Endothelial cells":"28.9","Fibroblasts":"11.5","Leydig cells":"43.7","Microglial cells":"11.9","Peritubular cells":"32.9","Sertoli cells":"19.3","Smooth muscle cells":"30.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"9.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035217"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"62000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm","Cell Junctions"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA035217":"AB_10669902"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.31e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"}},{"Gene":"PEBP4","Gene synonym":["CORK1","hPEBP4","MGC22776"],"Ensembl":"ENSG00000134020","Gene description":"Phosphatidylethanolamine binding protein 4","Uniprot":["Q96S96"],"Chromosome":"8","Position":"22713251-23000000","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"382.5","skeletal muscle":"670.8","tongue":"581.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"210.6","Alveolar cells type 2":"446.0","Cardiomyocytes":"133.5","Muller glia cells":"180.1","Prostatic glandular cells":"87.8","Skeletal myocytes":"347.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"lung cancer":"11.4","prostate cancer":"23.7","thyroid cancer":"35.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"29","RNA cell line specific nTPM":{"prostate cancer":"10.2"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 2","Pancreas - Exocrine glandular cells","Prostate - Prostate glandular cells","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes","Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025064"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000000","Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA025064":"AB_1855174"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-1"}},{"Gene":"PECAM1","Gene synonym":["CD31"],"Ensembl":"ENSG00000261371","Gene description":"Platelet and endothelial cell adhesion molecule 1","Uniprot":["P16284"],"Chromosome":"17","Position":"64319415-64413776","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Phagocytosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"455.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"691.0","Endothelial cells":"633.9","monocytes":"238.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"702.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"40.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Lung - Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004690","HPA004871"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA004690":"AB_1078462","HPA004871":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.98e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"}},{"Gene":"PEDS1","Gene synonym":["CarF","Kua","TMEM189"],"Ensembl":"ENSG00000240849","Gene description":"Plasmanylethanolamine desaturase 1","Uniprot":["A5PLL7"],"Chromosome":"20","Position":"50118254-50153734","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"188.2","Late spermatids":"125.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059549"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA059549":"AB_2684059"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.51e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.79e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"}},{"Gene":"PEDS1-UBE2V1","Gene synonym":["CROC-1B","Kua-UEV","TMEM189-UBE2V1"],"Ensembl":"ENSG00000124208","Gene description":"PEDS1-UBE2V1 readthrough","Uniprot":[],"Chromosome":"20","Position":"50081124-50153637","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"12.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"2.3","Inhibitory neurons":"2.2","Late spermatids":"4.7","Microglial cells":"1.8","Oligodendrocytes":"2.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"1.2"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052535","HPA053186"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA052535":"AB_2681863","HPA053186":"AB_2682073"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"}},{"Gene":"PELP1","Gene synonym":["MNAR"],"Ensembl":"ENSG00000141456","Gene description":"Proline, glutamate and leucine rich protein 1","Uniprot":["Q8IZL8"],"Chromosome":"17","Position":"4669774-4704337","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription"],"Molecular function":["Activator","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatogonia":"68.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053966","HPA056028","HPA060760"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA053966":"AB_2682325","HPA056028":"AB_2683013","HPA060760":"AB_2684355"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.44e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.07e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"}},{"Gene":"PEMT","Gene synonym":["PEMPT","PEMT2"],"Ensembl":"ENSG00000133027","Gene description":"Phosphatidylethanolamine N-methyltransferase","Uniprot":["Q9UBM1"],"Chromosome":"17","Position":"17505563-17591708","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"166.2","liver":"267.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"129.4","Hepatocytes":"215.6","Pancreatic endocrine cells":"173.5","Peritubular cells":"343.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042375","HPA073930"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Vesicles","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Endoplasmic reticulum","Mitochondria"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA042375":"AB_10796905","HPA073930":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.77e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"}},{"Gene":"PENK","Gene synonym":[],"Ensembl":"ENSG00000181195","Gene description":"Proenkephalin","Uniprot":["P01210"],"Chromosome":"8","Position":"56436674-56446671","Protein class":["Plasma proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":["Endorphin","Neuropeptide","Opioid peptide"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"adrenal gland":"376.2","brain":"164.1","testis":"129.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal respiratory cells":"715.4","Leydig cells":"1181.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"4.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"771.5"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Skin - Fibroblast_2","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"basal ganglia":"3626.9"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"basal ganglia":"923.2"},"Antibody":["HPA013138","CAB016390"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB016390":"AB_2161515","HPA013138":"AB_1855191"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-3"}},{"Gene":"PEPD","Gene synonym":[],"Ensembl":"ENSG00000124299","Gene description":"Peptidase D","Uniprot":["P12955"],"Chromosome":"19","Position":"33386950-33521791","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Collagen degradation"],"Molecular function":["Dipeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"209.5","kidney":"277.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"935.0","Proximal tubular cells":"996.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015599","HPA072045"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"860000000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015599":"AB_1855192","HPA072045":"AB_2732194"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.50e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"}},{"Gene":"PERM1","Gene synonym":["C1orf170","MGC13275","RP11-54O7.8"],"Ensembl":"ENSG00000187642","Gene description":"PPARGC1 and ESRR induced regulator, muscle 1","Uniprot":["Q5SV97"],"Chromosome":"1","Position":"975204-982093","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"55","RNA tissue specific nTPM":{"heart muscle":"68.8","skeletal muscle":"194.5","tongue":"135.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"3.7","Breast myoepithelial cells":"4.2","Early spermatids":"7.5","Horizontal cells":"5.1","Late spermatids":"5.9","Prostatic glandular cells":"4.0","Skeletal myocytes":"11.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031711","HPA031712"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031711":"AB_10669636","HPA031712":"AB_2674005"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.95e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"}},{"Gene":"PERP","Gene synonym":["dJ496H19.1","KCP1","KRTCAP1","PIGPC1","THW"],"Ensembl":"ENSG00000112378","Gene description":"P53 apoptosis effector related to PMP22","Uniprot":["Q96FX8"],"Chromosome":"6","Position":"138088505-138107419","Protein class":["Predicted membrane proteins"],"Biological process":["Apoptosis","Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"782.9","skin 1":"1115.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"3404.2","Squamous epithelial cells":"3820.8","Suprabasal keratinocytes":"7537.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"555.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"39.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"39.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Prostate - Prostate basal glandular cells","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022269"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA022269":"AB_1855219"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.46e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.73e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"}},{"Gene":"PET100","Gene synonym":["C19orf79"],"Ensembl":"ENSG00000229833","Gene description":"PET100 cytochrome c oxidase chaperone","Uniprot":["P0DJ07"],"Chromosome":"19","Position":"7629793-7631956","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067288"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA067288":"AB_2732762"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.81e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.97e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.44e-4"}},{"Gene":"PEX10","Gene synonym":["RNF69"],"Ensembl":"ENSG00000157911","Gene description":"Peroxisomal biogenesis factor 10","Uniprot":["O60683"],"Chromosome":"1","Position":"2403964-2413797","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Peroxisome biogenesis"],"Molecular function":null,"Disease involvement":["Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"203.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049755"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049755":"AB_2680867"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.50e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.16e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"}},{"Gene":"PEX11A","Gene synonym":["MGC119947","MGC138534","PEX11-ALPHA"],"Ensembl":"ENSG00000166821","Gene description":"Peroxisomal biogenesis factor 11 alpha","Uniprot":["O75192"],"Chromosome":"15","Position":"89677764-89690783","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Peroxisome biogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"37.4","Late spermatids":"38.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.57e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"}},{"Gene":"PEX11B","Gene synonym":[],"Ensembl":"ENSG00000131779","Gene description":"Peroxisomal biogenesis factor 11 beta","Uniprot":["O96011"],"Chromosome":"1","Position":"145911350-145918717","Protein class":["Disease related genes","Predicted membrane proteins"],"Biological process":["Peroxisome biogenesis"],"Molecular function":null,"Disease involvement":["Peroxisome biogenesis disorder"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017150","HPA050104"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA017150":null,"HPA050104":"AB_2681017"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.67e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.85e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-1"}},{"Gene":"PEX11G","Gene synonym":[],"Ensembl":"ENSG00000104883","Gene description":"Peroxisomal biogenesis factor 11 gamma","Uniprot":["Q96HA9"],"Chromosome":"19","Position":"7476875-7497449","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"26.4","testis":"29.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"88.9","Hepatocytes":"44.2","Late spermatids":"73.7","Proximal enterocytes":"37.5","Proximal tubular cells":"37.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"24.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Prostate - Prostate glandular cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069817"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069817":"AB_2686207"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.60e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.83e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"}},{"Gene":"PEX12","Gene synonym":[],"Ensembl":"ENSG00000108733","Gene description":"Peroxisomal biogenesis factor 12","Uniprot":["O00623"],"Chromosome":"17","Position":"35574795-35578863","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"19.1","Spermatocytes":"21.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069386"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069386":"AB_2686135"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"PEX13","Gene synonym":[],"Ensembl":"ENSG00000162928","Gene description":"Peroxisomal biogenesis factor 13","Uniprot":["Q92968"],"Chromosome":"2","Position":"61017225-61051990","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"145.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032141","HPA032142","CAB032689"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"CAB032689":"AB_2162137","HPA032141":"AB_2674176","HPA032142":"AB_10669676"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.07e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"}},{"Gene":"PEX14","Gene synonym":[],"Ensembl":"ENSG00000142655","Gene description":"Peroxisomal biogenesis factor 14","Uniprot":["O75381"],"Chromosome":"1","Position":"10472288-10630758","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"63.8","Syncytiotrophoblasts":"64.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046104","HPA049231"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli fibrillar center","Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Peroxisomes"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA046104":"AB_2679539","HPA049231":"AB_2680683"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"}},{"Gene":"PEX16","Gene synonym":[],"Ensembl":"ENSG00000121680","Gene description":"Peroxisomal biogenesis factor 16","Uniprot":["Q9Y5Y5"],"Chromosome":"11","Position":"45909663-45918812","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Peroxisome biogenesis"],"Molecular function":null,"Disease involvement":["Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043286"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043286":"AB_10794179"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.06e-4"}},{"Gene":"PEX26","Gene synonym":["FLJ20695"],"Ensembl":"ENSG00000215193","Gene description":"Peroxisomal biogenesis factor 26","Uniprot":["Q7Z412"],"Chromosome":"22","Position":"18077923-18105396","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"93.1","Proximal enterocytes":"85.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB070429"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB070429":"AB_11154363"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.92e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.10e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"}},{"Gene":"PEX3","Gene synonym":[],"Ensembl":"ENSG00000034693","Gene description":"Peroxisomal biogenesis factor 3","Uniprot":["P56589"],"Chromosome":"6","Position":"143450805-143490616","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Peroxisome biogenesis"],"Molecular function":null,"Disease involvement":["Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"73.0","Syncytiotrophoblasts":"78.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042830","HPA058006"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Nucleoplasm","Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA042830":"AB_10794918","HPA058006":"AB_2683576"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.80e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"}},{"Gene":"PEX6","Gene synonym":["PAF-2","PXAAA1"],"Ensembl":"ENSG00000124587","Gene description":"Peroxisomal biogenesis factor 6","Uniprot":["Q13608"],"Chromosome":"6","Position":"42963865-42979181","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Peroxisome biogenesis"],"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Deafness","Disease variant","Peroxisome biogenesis disorder","Zellweger syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"76.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025924","HPA074179"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA025924":"AB_1855230","HPA074179":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"}},{"Gene":"PFDN1","Gene synonym":["PFD1"],"Ensembl":"ENSG00000113068","Gene description":"Prefoldin subunit 1","Uniprot":["O60925"],"Chromosome":"5","Position":"140245035-140303113","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006499"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA006499":"AB_1079596"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.81e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"}},{"Gene":"PFN2","Gene synonym":[],"Ensembl":"ENSG00000070087","Gene description":"Profilin 2","Uniprot":["P35080"],"Chromosome":"3","Position":"149964904-150050788","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"454.0","Muller glia cells":"273.0","Proximal tubular cells":"207.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035611","CAB037073"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037073":"AB_1079600","HPA035611":"AB_10672870"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.93e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.42e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.19e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"}},{"Gene":"PGAP1","Gene synonym":["Bst1","FLJ12377","SPG67"],"Ensembl":"ENSG00000197121","Gene description":"Post-GPI attachment to proteins inositol deacylase 1","Uniprot":["Q75T13"],"Chromosome":"2","Position":"196833004-196927796","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"19.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"88.3","Inhibitory neurons":"101.9","Oligodendrocyte precursor cells":"124.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"}},{"Gene":"PGAP2","Gene synonym":["CWH43-N","FRAG1","MRT17","MRT21"],"Ensembl":"ENSG00000148985","Gene description":"Post-GPI attachment to proteins 2","Uniprot":["Q9UHJ9"],"Chromosome":"11","Position":"3797724-3826371","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"epididymis":"216.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"76.6","Early spermatids":"115.8","Late spermatids":"311.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Fibroblast_1","Skin - Keratinocyte (other)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063099"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA063099":"AB_2684940"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"}},{"Gene":"PGAP3","Gene synonym":["CAB2","MGC9753","PER1","PERLD1","PP1498"],"Ensembl":"ENSG00000161395","Gene description":"Post-GPI attachment to proteins phospholipase 3","Uniprot":["Q96FM1"],"Chromosome":"17","Position":"39671122-39696797","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"79.5","Esophageal cancer":"76.6"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016591"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA016591":"AB_1855203"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.94e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.82e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.89e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"}},{"Gene":"PGAP4","Gene synonym":["C9orf125","MGC12992","TMEM246"],"Ensembl":"ENSG00000165152","Gene description":"Post-GPI attachment to proteins GalNAc transferase 4","Uniprot":["Q9BRR3"],"Chromosome":"9","Position":"101473170-101533537","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"65.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011318","HPA054041","HPA057220"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA011318":"AB_2668482","HPA054041":"AB_2682353","HPA057220":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"}},{"Gene":"PGAP6","Gene synonym":["M83","TMEM6","TMEM8","TMEM8A"],"Ensembl":"ENSG00000129925","Gene description":"Post-glycosylphosphatidylinositol attachment to proteins 6","Uniprot":["Q9HCN3"],"Chromosome":"16","Position":"370788-387113","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"89.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"36.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051281","HPA064673"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA051281":"AB_2681418","HPA064673":"AB_2685317"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"}},{"Gene":"PGGHG","Gene synonym":["ATHL1","FLJ22635"],"Ensembl":"ENSG00000142102","Gene description":"Protein-glucosylgalactosylhydroxylysine glucosidase","Uniprot":["Q32M88"],"Chromosome":"11","Position":"289126-296107","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"pancreas":"657.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"52.1","Breast glandular cells":"35.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039383","HPA058829"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 20: Airway & Pancreas - Proteolysis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039383":"AB_10796225","HPA058829":"AB_2683830"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.12e-4"}},{"Gene":"PGLYRP2","Gene synonym":["PGLYRPL","PGRP-L","PGRPL","tagL","tagL-alpha","tagl-beta","TAGL-like"],"Ensembl":"ENSG00000161031","Gene description":"Peptidoglycan recognition protein 2","Uniprot":["Q96PD5"],"Chromosome":"19","Position":"15468645-15498956","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"45","RNA tissue specific nTPM":{"liver":"258.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Hepatocytes":"133.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"16","RNA cancer specific FPKM":{"liver cancer":"42.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"3.4","monocytes":"5.1","T-cells":"2.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"6.0","breast cancer":"2.8"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Liver - Hepatocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033468","HPA046311","HPA075237"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"87000000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB033468":"AB_1127187","HPA046311":"AB_2679621","HPA075237":"AB_2686739"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-4"}},{"Gene":"PGR","Gene synonym":["NR3C3","PR"],"Ensembl":"ENSG00000082175","Gene description":"Progesterone receptor","Uniprot":["P06401"],"Chromosome":"11","Position":"101029624-101129813","Protein class":["Cancer-related genes","FDA approved drug targets","Nuclear receptors","Predicted intracellular proteins","Transcription factors","Transporters"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"cervix":"63.9","endometrium 1":"103.4","fallopian tube":"34.3","smooth muscle":"78.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"70.7","Endometrial ciliated cells":"84.1","Endometrial stromal cells":"166.1","Glandular and luminal cells":"75.1","Late spermatids":"42.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"breast cancer":"10.1","endometrial cancer":"11.1"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"hypothalamus":"7.7","thalamus":"9.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"29","RNA cell line specific nTPM":{"breast cancer":"7.6"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000068","HPA004751","HPA008428","HPA017176","CAB055100"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000068":"AB_442124","CAB055100":"AB_2532076","HPA004751":"AB_1079681","HPA008428":"AB_1079680","HPA017176":"AB_1855728"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.76e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-3"}},{"Gene":"PGRMC1","Gene synonym":["HPR6.6"],"Ensembl":"ENSG00000101856","Gene description":"Progesterone receptor membrane component 1","Uniprot":["O00264"],"Chromosome":"X","Position":"119236245-119244466","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"677.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"479.3","Theca cells":"641.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Colon - Colon enteroendocrine cells","Liver - Hepatocytes","Liver - Hepatocytes","Skin - Sebaceous gland cells","Testis - Leydig cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002877","HPA064724"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA002877":"AB_1079602","HPA064724":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"}},{"Gene":"PGRMC2","Gene synonym":["DG6","PMBP"],"Ensembl":"ENSG00000164040","Gene description":"Progesterone receptor membrane component 2","Uniprot":["O15173"],"Chromosome":"4","Position":"128269237-128288829","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"316.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041172","HPA058652"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"76000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nuclear bodies","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041172":"AB_2677345","HPA058652":"AB_2683786"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.60e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"}},{"Gene":"PHACTR1","Gene synonym":["dJ257A7.2","KIAA1733","RPEL1"],"Ensembl":"ENSG00000112137","Gene description":"Phosphatase and actin regulator 1","Uniprot":["Q9C0D0"],"Chromosome":"6","Position":"12716554-13287843","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Actin-binding","Protein phosphatase inhibitor"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"38.0","brain":"52.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"1928.3","Inhibitory neurons":"511.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"melanoma":"10.2"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"basal ganglia":"52.1","cerebral cortex":"27.3","hippocampal formation":"14.8"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"37.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"B-cells":"13.6","dendritic cells":"37.8","granulocytes":"18.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"23.5","lymphoma":"29.7","Myeloma":"43.7","skin cancer":"70.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029755","HPA029756","HPA029757"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA029755":"AB_10600089","HPA029756":"AB_10601852","HPA029757":"AB_10669870"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.48e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"}},{"Gene":"PHB2","Gene synonym":["Bap37","BCAP37","p22","REA"],"Ensembl":"ENSG00000215021","Gene description":"Prohibitin 2","Uniprot":["Q99623"],"Chromosome":"12","Position":"6965327-6970780","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Receptor","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB014889","CAB026335","HPA039874"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"77000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB014889":null,"CAB026335":"AB_2283865","HPA039874":"AB_2616448"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.80e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"}},{"Gene":"PHEX","Gene synonym":["HPDR","HPDR1","HYP","HYP1","PEX","XLH"],"Ensembl":"ENSG00000102174","Gene description":"Phosphate regulating endopeptidase homolog X-linked","Uniprot":["P78562"],"Chromosome":"X","Position":"22032325-22251310","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Biomineralization"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"2.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"dendritic cells":"158.2","Granulosa cells":"159.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"thyroid cancer":"5.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"37","RNA blood cell specific nTPM":{"plasmacytoid DC":"4.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"37","RNA blood lineage specific nTPM":{"dendritic cells":"4.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.51e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"}},{"Gene":"PHF12","Gene synonym":["KIAA1523","PF1"],"Ensembl":"ENSG00000109118","Gene description":"PHD finger protein 12","Uniprot":["Q96QT6"],"Chromosome":"17","Position":"28905250-28951771","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"40.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"40.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021410","HPA021452"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA021410":"AB_1855287","HPA021452":"AB_2670708"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"}},{"Gene":"PHKG1","Gene synonym":["PHKG"],"Ensembl":"ENSG00000164776","Gene description":"Phosphorylase kinase catalytic subunit gamma 1","Uniprot":["Q16816"],"Chromosome":"7","Position":"56080283-56092996","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism","Glycogen metabolism"],"Molecular function":["Calmodulin-binding","Kinase","Muscle protein","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"skeletal muscle":"264.6","tongue":"172.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"109.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"glioma":"23.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012057"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012057":"AB_1855305"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"}},{"Gene":"PHKG2","Gene synonym":[],"Ensembl":"ENSG00000156873","Gene description":"Phosphorylase kinase catalytic subunit gamma 2","Uniprot":["P15735"],"Chromosome":"16","Position":"30748293-30761176","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism","Glycogen metabolism"],"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Glycogen storage disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"testis":"130.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"1559.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065618","HPA068751"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA065618":"AB_2685520","HPA068751":"AB_2686025"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.90e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.92e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.90e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.02e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"}},{"Gene":"PHLDB1","Gene synonym":["FLJ00141","KIAA0638","LL5a"],"Ensembl":"ENSG00000019144","Gene description":"Pleckstrin homology like domain family B member 1","Uniprot":["Q86UU1"],"Chromosome":"11","Position":"118606440-118658031","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"133.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"85.0","Late spermatids":"113.1","Oligodendrocytes":"230.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037959","HPA038448"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA037959":"AB_10673651","HPA038448":"AB_10697390"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.36e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"PHLDB2","Gene synonym":["FLJ21791","LL5b","LL5beta"],"Ensembl":"ENSG00000144824","Gene description":"Pleckstrin homology like domain family B member 2","Uniprot":["Q86SQ0"],"Chromosome":"3","Position":"111732497-111976517","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"117.6","Basal keratinocytes":"166.3","Cardiomyocytes":"150.5","Mucus glandular cells":"115.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035146","HPA035147"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035146":"AB_10600927","HPA035147":"AB_2674492"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.59e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.03e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"}},{"Gene":"PHTF1","Gene synonym":["PHTF"],"Ensembl":"ENSG00000116793","Gene description":"Putative homeodomain transcription factor 1","Uniprot":["Q9UMS5"],"Chromosome":"1","Position":"113696831-113759489","Protein class":["Plasma proteins","Predicted membrane proteins","Transcription factors"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"211.5","Excitatory neurons":"92.0","Inhibitory neurons":"100.3","Late spermatids":"127.7","Spermatocytes":"123.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059486"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Nuclear bodies"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA059486":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"PHTF2","Gene synonym":["DKFZp434D166"],"Ensembl":"ENSG00000006576","Gene description":"Putative homeodomain transcription factor 2","Uniprot":["Q8N3S3"],"Chromosome":"7","Position":"77798792-77957503","Protein class":["Predicted membrane proteins","Transcription factors"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"112.7","tongue":"57.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"107.5","Inhibitory neurons":"92.5","Oligodendrocyte precursor cells":"87.6","Oligodendrocytes":"136.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"16.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"25.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012312"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA012312":"AB_2668649"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.09e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"}},{"Gene":"PI16","Gene synonym":["CD364","dJ90K10.5","MGC45378","MSMBBP"],"Ensembl":"ENSG00000164530","Gene description":"Peptidase inhibitor 16","Uniprot":["Q6UXB8"],"Chromosome":"6","Position":"36948263-36964837","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Protease inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"140.6","heart muscle":"127.7","vagina":"127.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Fibroblasts":"173.6","Leydig cells":"203.7","Oligodendrocytes":"63.6","Peritubular cells":"144.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"15.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"66.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"66.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Kidney cancer":"13.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Colon - Fibroblasts","Heart muscle - Fibroblasts","Pancreas - Fibroblasts","Prostate - Fibroblasts","Skin - Fibroblast_1","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"spinal cord":"33.2"},"Antibody":["HPA076574"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2900000000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA076574":"AB_2732314"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"}},{"Gene":"PI4KA","Gene synonym":["PI4K-ALPHA","pi4K230","PIK4CA"],"Ensembl":"ENSG00000241973","Gene description":"Phosphatidylinositol 4-kinase alpha","Uniprot":["P42356"],"Chromosome":"22","Position":"20707691-20859417","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"206.2","Inhibitory neurons":"124.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009092","HPA075515"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB009092":"AB_2164033","HPA075515":"AB_2686753"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.24e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.22e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"}},{"Gene":"PI4KB","Gene synonym":["PI4K-BETA","pi4K92","PIK4CB"],"Ensembl":"ENSG00000143393","Gene description":"Phosphatidylinositol 4-kinase beta","Uniprot":["Q9UBF8"],"Chromosome":"1","Position":"151291797-151327715","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Lipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006280","HPA006281","CAB022071"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB022071":null,"HPA006280":"AB_1079613","HPA006281":"AB_1079614"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.97e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.23e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.78e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"}},{"Gene":"PIANP","Gene synonym":["C12orf53","DKFZp547D2210","PANP"],"Ensembl":"ENSG00000139200","Gene description":"PILR alpha associated neural protein","Uniprot":["Q8IYJ0"],"Chromosome":"12","Position":"6693791-6700815","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"90.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"14.2","Excitatory neurons":"24.1","Horizontal cells":"27.6","Inhibitory neurons":"23.3","Oligodendrocyte precursor cells":"15.4","Peritubular cells":"14.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"14.7","testis cancer":"7.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"28.0"},"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010631"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA010631":"AB_10603680"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"}},{"Gene":"PIAS2","Gene synonym":["ARIP3","miz","PIASX-ALPHA","PIASX-BETA","ZMIZ4"],"Ensembl":"ENSG00000078043","Gene description":"Protein inhibitor of activated STAT 2","Uniprot":["O75928"],"Chromosome":"18","Position":"46803218-46920160","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"67.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"468.3","Late spermatids":"565.3","Spermatocytes":"210.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068792","HPA077584"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA068792":"AB_2686037","HPA077584":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.27e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"}},{"Gene":"PIEZO1","Gene synonym":["FAM38A","KIAA0233"],"Ensembl":"ENSG00000103335","Gene description":"Piezo type mechanosensitive ion channel component 1","Uniprot":["Q92508"],"Chromosome":"16","Position":"88715338-88785220","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"67.4","Alveolar cells type 1":"67.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047185"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047185":"AB_2679973"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.37e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.36e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.78e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.89e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"}},{"Gene":"PIEZO2","Gene synonym":["C18orf30","C18orf58","FAM38B","FAM38B2","FLJ23144","FLJ23403","FLJ34907","HsT748","HsT771"],"Ensembl":"ENSG00000154864","Gene description":"Piezo type mechanosensitive ion channel component 2","Uniprot":["Q9H5I5"],"Chromosome":"18","Position":"10666483-11149569","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sensory transduction","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"58.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Oligodendrocytes":"377.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Colon - Enteric glia cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015986","HPA031974","HPA040616"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015986":"AB_1848395","HPA031974":"AB_10603675","HPA040616":"AB_2677043"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.57e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"}},{"Gene":"PIGA","Gene synonym":["GPI3"],"Ensembl":"ENSG00000165195","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class A","Uniprot":["P37287"],"Chromosome":"X","Position":"15319452-15335554","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis","Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"59.6","Langerhans cells":"52.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"22.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001174"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001174":"AB_2666220"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.64e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"}},{"Gene":"PIGB","Gene synonym":[],"Ensembl":"ENSG00000069943","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class B","Uniprot":["Q92521"],"Chromosome":"15","Position":"55318960-55355648","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"31.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039929"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039929":"AB_10673539"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"}},{"Gene":"PIGC","Gene synonym":[],"Ensembl":"ENSG00000135845","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class C","Uniprot":["Q92535"],"Chromosome":"1","Position":"172370189-172444086","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"90.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036663"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036663":"AB_10669912"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.43e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"}},{"Gene":"PIGF","Gene synonym":[],"Ensembl":"ENSG00000151665","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class F","Uniprot":["Q07326"],"Chromosome":"2","Position":"46580937-46617055","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051389"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051389":"AB_2681464"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.39e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"}},{"Gene":"PIGG","Gene synonym":["FLJ20265","GPI7","LAS21"],"Ensembl":"ENSG00000174227","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class G","Uniprot":["Q5H8A4"],"Chromosome":"4","Position":"499210-540200","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015997"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015997":"AB_2164679"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"}},{"Gene":"PIGH","Gene synonym":["GPI-H"],"Ensembl":"ENSG00000100564","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class H","Uniprot":["Q14442"],"Chromosome":"14","Position":"67581955-67600286","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Autism spectrum disorder","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Muller glia cells":"86.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031624"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031624":"AB_10601046"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.68e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"}},{"Gene":"PIGK","Gene synonym":["GPI8","hGPI8"],"Ensembl":"ENSG00000142892","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class K","Uniprot":["Q92643"],"Chromosome":"1","Position":"77088989-77219430","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"79.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056383","HPA057040"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056383":"AB_2683109","HPA057040":"AB_2683319"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.68e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"}},{"Gene":"PIGM","Gene synonym":["GPI-MT-I"],"Ensembl":"ENSG00000143315","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class M","Uniprot":["Q9H3S5"],"Chromosome":"1","Position":"160024953-160031990","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047418"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047418":"AB_2680039"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.27e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"}},{"Gene":"PIGN","Gene synonym":["MCD4","PIG-N"],"Ensembl":"ENSG00000197563","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class N","Uniprot":["O95427"],"Chromosome":"18","Position":"61905255-62187118","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"116.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Stomach - Parietal cells","Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039922","HPA040374"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039922":"AB_10805597","HPA040374":"AB_10794738"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.51e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"}},{"Gene":"PIGO","Gene synonym":["DKFZp434M222","FLJ00135"],"Ensembl":"ENSG00000165282","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class O","Uniprot":["Q8TEQ8"],"Chromosome":"9","Position":"35088688-35096601","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014905"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA014905":"AB_1855369"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.05e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"}},{"Gene":"PIGP","Gene synonym":["DCRC","DSCR5","DSRC"],"Ensembl":"ENSG00000185808","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class P","Uniprot":["P57054"],"Chromosome":"21","Position":"37062846-37073170","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"374.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026921"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA026921":"AB_1847874"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"}},{"Gene":"PIGQ","Gene synonym":["GPI1","hGPI1"],"Ensembl":"ENSG00000007541","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class Q","Uniprot":["Q9BRB3"],"Chromosome":"16","Position":"566995-584109","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"59.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039105","HPA039828","HPA061414"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA039105":"AB_10796221","HPA039828":"AB_10795158","HPA061414":"AB_2684508"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.53e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"}},{"Gene":"PIGR","Gene synonym":[],"Ensembl":"ENSG00000162896","Gene description":"Polymeric immunoglobulin receptor","Uniprot":["P01833"],"Chromosome":"1","Position":"206928522-206946466","Protein class":["Cancer-related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"2641.0","salivary gland":"1645.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"8805.9","Intestinal goblet cells":"2822.9","Paneth cells":"2841.8","Proximal enterocytes":"1621.1","Undifferentiated cells":"3386.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"731.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"28.8","colorectal cancer":"31.1","Gastric cancer":"56.9"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Alveolar cells type 2","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006154","CAB009454","HPA012012"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009454":"AB_2164819","HPA006154":"AB_1855370","HPA012012":"AB_1855371"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.22e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.57e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.08e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"}},{"Gene":"PIGS","Gene synonym":[],"Ensembl":"ENSG00000087111","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class S","Uniprot":["Q96S52"],"Chromosome":"17","Position":"28553383-28571794","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"103.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Stomach - Macrophages","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018149"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018149":"AB_1855373"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.31e-4"}},{"Gene":"PIGT","Gene synonym":[],"Ensembl":"ENSG00000124155","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class T","Uniprot":["Q969N2"],"Chromosome":"20","Position":"45416084-45456934","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Skin - Fibroblast_1","Skin - Fibroblast_2","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.51e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"}},{"Gene":"PIGU","Gene synonym":["bA346K17.2","CDC91L1","GAB1"],"Ensembl":"ENSG00000101464","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class U","Uniprot":["Q9H490"],"Chromosome":"20","Position":"34560542-34698790","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"74.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041706","HPA046766"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA041706":"AB_2677627","HPA046766":"AB_2679794"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"}},{"Gene":"PIGV","Gene synonym":["FLJ20477"],"Ensembl":"ENSG00000060642","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class V","Uniprot":["Q9NUD9"],"Chromosome":"1","Position":"26787054-26800659","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"53.8","Late spermatids":"97.7","Spermatocytes":"74.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054181"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA054181":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.60e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-3"}},{"Gene":"PIGW","Gene synonym":["FLJ37433","Gwt1"],"Ensembl":"ENSG00000277161","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class W","Uniprot":["Q7Z7B1"],"Chromosome":"17","Position":"36534987-36539310","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"19.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023499"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA023499":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"}},{"Gene":"PIGX","Gene synonym":["FLJ20522"],"Ensembl":"ENSG00000163964","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class X","Uniprot":["Q8TBF5"],"Chromosome":"3","Position":"196639775-196736007","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"87.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"87.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029409","HPA073301"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA029409":"AB_10610280","HPA073301":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.12e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.45e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"}},{"Gene":"PIGY","Gene synonym":["MGC14156"],"Ensembl":"ENSG00000255072","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class Y","Uniprot":["Q3MUY2"],"Chromosome":"4","Position":"88520998-88523776","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059018"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059018":"AB_2683884"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PIGZ","Gene synonym":["FLJ12768","MGC52163","SMP3"],"Ensembl":"ENSG00000119227","Gene description":"Phosphatidylinositol glycan anchor biosynthesis class Z","Uniprot":["Q86VD9"],"Chromosome":"3","Position":"196946356-196969060","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["GPI-anchor biosynthesis"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"39.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"170.1","Intestinal goblet cells":"64.0","Paneth cells":"81.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058599","HPA059920"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058599":"AB_2683771","HPA059920":"AB_2684162"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.60e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-3"}},{"Gene":"PIH1D1","Gene synonym":["FLJ20643","MOT48","NOP17","Pih1"],"Ensembl":"ENSG00000104872","Gene description":"PIH1 domain containing 1","Uniprot":["Q9NWS0"],"Chromosome":"19","Position":"49446298-49453497","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047258"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA047258":"AB_10964561"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"}},{"Gene":"PIK3AP1","Gene synonym":["BCAP","FLJ35564"],"Ensembl":"ENSG00000155629","Gene description":"Phosphoinositide-3-kinase adaptor protein 1","Uniprot":["Q6ZUJ8"],"Chromosome":"10","Position":"96593315-96720514","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"83.2","lymphoid tissue":"62.3","salivary gland":"73.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"64.6","Hofbauer cells":"63.6","Kupffer cells":"118.5","Macrophages":"97.0","Microglial cells":"59.3","monocytes":"126.1","Serous glandular cells":"60.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"44.7","memory B-cell":"48.3","naive B-cell":"44.5","non-classical monocyte":"123.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"48.3","monocytes":"123.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"53.0","lymphoma":"85.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Lung - Neutrophil_2","Skeletal muscle - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026136","HPA038452"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"CAB026136":null,"HPA038452":"AB_2676019"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"}},{"Gene":"PIK3IP1","Gene synonym":["HGFL","MGC17330","TrIP"],"Ensembl":"ENSG00000100100","Gene description":"Phosphoinositide-3-kinase interacting protein 1","Uniprot":["Q96FE7"],"Chromosome":"22","Position":"31281594-31292534","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"149.3","T-cells":"167.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"499.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"499.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6800000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.80e-4"}},{"Gene":"PIK3R5","Gene synonym":["p101","P101-PI3K"],"Ensembl":"ENSG00000141506","Gene description":"Phosphoinositide-3-kinase regulatory subunit 5","Uniprot":["Q8WYR1"],"Chromosome":"17","Position":"8878911-8965712","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"87.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"34.9","Kupffer cells":"34.8","Langerhans cells":"47.6","Macrophages":"39.6","Microglial cells":"77.5","monocytes":"38.6","NK-cells":"36.9","Schwann cells":"25.4","T-cells":"24.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"11.2","lymphoma":"5.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Pancreas - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044505","HPA052247","HPA052412"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA044505":"AB_2678964","HPA052247":"AB_2681772","HPA052412":"AB_2681823"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"}},{"Gene":"PILRA","Gene synonym":["FDF03"],"Ensembl":"ENSG00000085514","Gene description":"Paired immunoglobin like type 2 receptor alpha","Uniprot":["Q9UKJ1"],"Chromosome":"7","Position":"100367530-100400096","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"131.9","Kupffer cells":"73.6","Langerhans cells":"83.7","Leydig cells":"51.3","Macrophages":"120.0","monocytes":"302.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1659.8","non-classical monocyte":"1146.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1659.8","monocytes":"1146.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"6.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056132"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056132":"AB_2683048"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.99e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"}},{"Gene":"PILRB","Gene synonym":["FDFACT1","FDFACT2"],"Ensembl":"ENSG00000121716","Gene description":"Paired immunoglobin like type 2 receptor beta","Uniprot":["Q9UKJ0"],"Chromosome":"7","Position":"100352176-100367733","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"31.3","NK-cells":"58.0","Rod photoreceptor cells":"36.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"221.1","neutrophil":"141.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"221.1","monocytes":"75.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026750"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA026750":"AB_10670828"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-3"}},{"Gene":"PIM1","Gene synonym":["PIM"],"Ensembl":"ENSG00000137193","Gene description":"Pim-1 proto-oncogene, serine\/threonine kinase","Uniprot":["P11309"],"Chromosome":"6","Position":"37170152-37175428","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"219.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"187.4","Suprabasal keratinocytes":"212.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"321.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"321.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"186.8"},"RNA tissue cell type enrichment":["Colon - Neutrophils"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003941","CAB017040"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Nucleoli"],"Antibody RRID":{"CAB017040":null,"HPA003941":"AB_1079618"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.73e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"}},{"Gene":"PIM2","Gene synonym":[],"Ensembl":"ENSG00000102096","Gene description":"Pim-2 proto-oncogene, serine\/threonine kinase","Uniprot":["Q9P1W9"],"Chromosome":"X","Position":"48913182-48919024","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cell cycle"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"102.3","intestine":"87.6","lymphoid tissue":"163.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Plasma cells":"702.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"testis cancer":"171.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Myeloma":"803.5"},"RNA tissue cell type enrichment":["Adipose visceral - Plasma cells","Breast - Plasma cells","Lung - Plasma cells","Stomach - Plasma cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000285"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA000285":"AB_1079619"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.05e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.17e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"}},{"Gene":"PIM3","Gene synonym":[],"Ensembl":"ENSG00000198355","Gene description":"Pim-3 proto-oncogene, serine\/threonine kinase","Uniprot":["Q86V86"],"Chromosome":"22","Position":"49960768-49964072","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"392.9","Langerhans cells":"450.7","Syncytiotrophoblasts":"413.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"20.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068758"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA068758":"AB_2686026"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.68e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-3"}},{"Gene":"PIP4P1","Gene synonym":["C14orf9","MGC26684","TMEM55B"],"Ensembl":"ENSG00000165782","Gene description":"Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1","Uniprot":["Q86T03"],"Chromosome":"14","Position":"20457681-20461465","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"172.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048528"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048528":"AB_2680427"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"}},{"Gene":"PIP4P2","Gene synonym":["DKFZp762O076","TMEM55A"],"Ensembl":"ENSG00000155099","Gene description":"Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2","Uniprot":["Q8N4L2"],"Chromosome":"8","Position":"90993802-91040872","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"76.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"76.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014591"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014591":"AB_1858124"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.54e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.76e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.01e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"}},{"Gene":"PIRT","Gene synonym":[],"Ensembl":"ENSG00000233670","Gene description":"Phosphoinositide interacting regulator of transient receptor potential channels","Uniprot":["P0C851"],"Chromosome":"17","Position":"10822470-10838087","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"24.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"2.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"40","RNA cancer specific FPKM":{"glioma":"5.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"39","RNA cell line specific nTPM":{"Neuroblastoma":"3.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042337"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA042337":"AB_10794795"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PISD","Gene synonym":["dJ858B16.2","PSDC"],"Ensembl":"ENSG00000241878","Gene description":"Phosphatidylserine decarboxylase","Uniprot":["Q9UG56"],"Chromosome":"22","Position":"31618491-31662432","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Decarboxylase","Lyase"],"Disease involvement":["Cataract","Deafness","Disease variant","Dwarfism","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"222.6","Syncytiotrophoblasts":"212.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031090","HPA031091"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA031090":"AB_10600114","HPA031091":"AB_10600893"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.27e-5"}},{"Gene":"PITPNM1","Gene synonym":["DRES9","NIR2","PITPNM","Rd9","RDGB","RDGB1","RDGBA1"],"Ensembl":"ENSG00000110697","Gene description":"Phosphatidylinositol transfer protein membrane associated 1","Uniprot":["O00562"],"Chromosome":"11","Position":"67491768-67506263","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"81.0","Endometrial ciliated cells":"63.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060227"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA060227":"AB_2684226"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"}},{"Gene":"PITPNM2","Gene synonym":["NIR3","RDGB2","RDGBA2"],"Ensembl":"ENSG00000090975","Gene description":"Phosphatidylinositol transfer protein membrane associated 2","Uniprot":["Q9BZ72"],"Chromosome":"12","Position":"122983480-123150015","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"87.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"32.6","Excitatory neurons":"50.6","Inhibitory neurons":"40.3","Late spermatids":"87.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003414","HPA003978"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA003414":"AB_1855410","HPA003978":"AB_1855411"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"}},{"Gene":"PITPNM3","Gene synonym":["ACKR6","CORD5","NIR1","RDGBA3"],"Ensembl":"ENSG00000091622","Gene description":"PITPNM family member 3","Uniprot":["Q9BZ71"],"Chromosome":"17","Position":"6451263-6556555","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"60.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"20.2","Inhibitory neurons":"23.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"23","RNA blood cell specific nTPM":{"neutrophil":"2.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"granulocytes":"2.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Sinusoid Endothelial cells","Lung - Alveolar cells type 2","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022432","HPA059005"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA022432":"AB_2670936","HPA059005":"AB_2683876"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.67e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"}},{"Gene":"PITRM1","Gene synonym":["hMP1","KIAA1104","MP1","PreP"],"Ensembl":"ENSG00000107959","Gene description":"Pitrilysin metallopeptidase 1","Uniprot":["Q5JRX3"],"Chromosome":"10","Position":"3137728-3172841","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"165.5","Late spermatids":"121.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006753","HPA006754"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA006753":"AB_1079624","HPA006754":"AB_1079623"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"}},{"Gene":"PKD1","Gene synonym":["PBP","Pc-1","TRPP1"],"Ensembl":"ENSG00000008710","Gene description":"Polycystin 1, transient receptor potential channel interacting","Uniprot":["P98161"],"Chromosome":"16","Position":"2088708-2135898","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"72.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"136.2","Horizontal cells":"87.2","Inhibitory neurons":"98.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"65.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB046448"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"840000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB046448":"AB_2163360"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.43e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.35e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.38e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"}},{"Gene":"PKD1L1","Gene synonym":["PRO19563"],"Ensembl":"ENSG00000158683","Gene description":"Polycystin 1 like 1, transient receptor potential channel interacting","Uniprot":["Q8TDX9"],"Chromosome":"7","Position":"47740202-47948466","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":["Heterotaxy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"13.0","Excitatory neurons":"25.3","Inhibitory neurons":"36.9","Late spermatids":"9.0","Microglial cells":"14.6","Oligodendrocyte precursor cells":"11.1","Oligodendrocytes":"16.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020422","HPA022424"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA020422":"AB_1855434","HPA022424":"AB_1855435"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"}},{"Gene":"PKD1L3","Gene synonym":[],"Ensembl":"ENSG00000277481","Gene description":"Polycystin 1 like 3, transient receptor potential channel interacting","Uniprot":["Q7Z443"],"Chromosome":"16","Position":"71929538-71999978","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"1.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"2.5","Inhibitory neurons":"2.1","Microglial cells":"1.8","Oligodendrocytes":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"}},{"Gene":"PKD2","Gene synonym":["Pc-2","PC2","PKD4","TRPP2"],"Ensembl":"ENSG00000118762","Gene description":"Polycystin 2, transient receptor potential cation channel","Uniprot":["Q13563"],"Chromosome":"4","Position":"88007635-88077777","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Potassium transport","Transport","Wnt signaling pathway"],"Molecular function":["Calcium channel","Ion channel","Potassium channel","Voltage-gated channel"],"Disease involvement":["Ciliopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"127.2","Inhibitory neurons":"145.4","Microglial cells":"93.0","Oligodendrocyte precursor cells":"171.4","Oligodendrocytes":"207.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Fibroblast_1","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004544","HPA015794","HPA055297"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004544":"AB_672377","HPA015794":"AB_1855437","HPA055297":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"}},{"Gene":"PKD2L1","Gene synonym":["PCL","PKD2L","PKDL","TRPP3"],"Ensembl":"ENSG00000107593","Gene description":"Polycystin 2 like 1, transient receptor potential cation channel","Uniprot":["Q9P0L9"],"Chromosome":"10","Position":"100288149-100330264","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.8","lymphoid tissue":"7.9","retina":"13.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"5.0","Early spermatids":"9.7","Hofbauer cells":"13.9","Horizontal cells":"19.9","Late spermatids":"21.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"2.3","Uterine cancer":"1.1"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022621","HPA070002"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Actin filaments","Cytosol"],"Antibody RRID":{"CAB022621":null,"HPA070002":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-7"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"}},{"Gene":"PKD2L2","Gene synonym":["TRPP5"],"Ensembl":"ENSG00000078795","Gene description":"Polycystin 2 like 2, transient receptor potential cation channel","Uniprot":["Q9NZM6"],"Chromosome":"5","Position":"137887968-137942747","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"8.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"54.6","Spermatocytes":"43.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041903","HPA043634"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA041903":"AB_2677734","HPA043634":"AB_2678591"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"}},{"Gene":"PKDREJ","Gene synonym":[],"Ensembl":"ENSG00000130943","Gene description":"Polycystin family receptor for egg jelly","Uniprot":["Q9NTG1"],"Chromosome":"22","Position":"46255663-46263343","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"3.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7","Early spermatids":"4.4","Late spermatids":"1.3","Spermatocytes":"7.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034587"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034587":"AB_10670570"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"PKHD1","Gene synonym":["ARPKD","FCYT","FPC","TIGM1"],"Ensembl":"ENSG00000170927","Gene description":"PKHD1 ciliary IPT domain containing fibrocystin\/polyductin","Uniprot":["P08F94"],"Chromosome":"6","Position":"51615299-52087613","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Ciliopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"epididymis":"4.7","kidney":"13.6","pancreas":"9.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"339.2","Late spermatids":"99.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"pancreatic cancer":"1.4","renal cancer":"5.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"2.0","Kidney cancer":"2.1"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031227"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031227":"AB_10602068"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.74e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"}},{"Gene":"PKHD1L1","Gene synonym":[],"Ensembl":"ENSG00000205038","Gene description":"PKHD1 like 1","Uniprot":["Q86WI1"],"Chromosome":"8","Position":"109362461-109537207","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"25.5","thyroid gland":"68.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"25.2","Endometrial ciliated cells":"59.1","Endothelial cells":"39.7","Glandular and luminal cells":"58.1","Plasma cells":"47.5","Thymic epithelial cells":"194.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"endometrial cancer":"5.2","ovarian cancer":"1.9","thyroid cancer":"3.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Mesothelial cells","Skeletal muscle - Smooth muscle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044458"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044458":"AB_2678949"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"}},{"Gene":"PKMYT1","Gene synonym":["MYT1","PPP1R126"],"Ensembl":"ENSG00000127564","Gene description":"Protein kinase, membrane associated tyrosine\/threonine 1","Uniprot":["Q99640"],"Chromosome":"16","Position":"2968024-2980479","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"27.6","testis":"56.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"22.3","Erythroid cells":"29.4","Extravillous trophoblasts":"55.3","Plasma cells":"27.6","Spermatocytes":"114.6","Spermatogonia":"30.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"T-reg":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"1.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Mitotic cells (Colon)","Heart muscle - Mitotic cells (Heart)","Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Thyroid - Mitotic cells (Thyroid)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068860"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Nucleoli"],"Antibody RRID":{"HPA068860":"AB_2686050"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.33e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.37e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"}},{"Gene":"PKN2","Gene synonym":["Pak-2","PRK2","PRKCL2","STK7"],"Ensembl":"ENSG00000065243","Gene description":"Protein kinase N2","Uniprot":["Q16513"],"Chromosome":"1","Position":"88684222-88836255","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cell adhesion","Cell cycle","Cell division","Cilium biogenesis\/degradation","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"80.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"80.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034861","HPA057913"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Plasma membrane","Intermediate filaments","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Intermediate filaments"],"Subcellular additional location":["Nuclear bodies","Plasma membrane","Centrosome","Cytosol"],"Antibody RRID":{"HPA034861":"AB_2674363","HPA057913":"AB_2732617"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.67e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"}},{"Gene":"PKP1","Gene synonym":["B6P"],"Ensembl":"ENSG00000081277","Gene description":"Plakophilin 1","Uniprot":["Q13835"],"Chromosome":"1","Position":"201283452-201332993","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Developmental protein"],"Disease involvement":["Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"esophagus":"416.7","skin 1":"699.9","vagina":"200.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal keratinocytes":"315.6","Squamous epithelial cells":"258.3","Suprabasal keratinocytes":"748.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"125.5","head and neck cancer":"295.4","lung cancer":"79.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"171.3","head and neck cancer":"98.1"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027221","CAB033130"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2500000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB033130":"AB_2164139","HPA027221":"AB_10599737"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-3"}},{"Gene":"PKP2","Gene synonym":[],"Ensembl":"ENSG00000057294","Gene description":"Plakophilin 2","Uniprot":["Q99959"],"Chromosome":"12","Position":"32790755-32896777","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"188.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"550.2","Extravillous trophoblasts":"203.9","monocytes":"163.0","Mucus glandular cells":"138.9","Salivary duct cells":"181.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"8.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"149.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hippocampal formation":"20.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014314","CAB037336","HPA056908"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB037336":null,"HPA014314":"AB_1855451","HPA056908":"AB_2683272"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.55e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.79e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"}},{"Gene":"PLA2G15","Gene synonym":["GXVPLA2","LLPL","LYPLA3"],"Ensembl":"ENSG00000103066","Gene description":"Phospholipase A2 group XV","Uniprot":["Q8NCC3"],"Chromosome":"16","Position":"68245304-68261058","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid metabolism","Lipid degradation","Lipid metabolism"],"Molecular function":["Acyltransferase","Hydrolase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"58.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"104.5","Syncytiotrophoblasts":"46.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Lung - Macrophages","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041702","HPA041727"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041702":"AB_10794486","HPA041727":"AB_10793931"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"}},{"Gene":"PLA2G2F","Gene synonym":[],"Ensembl":"ENSG00000158786","Gene description":"Phospholipase A2 group IIF","Uniprot":["Q9BZM2"],"Chromosome":"1","Position":"20139323-20150381","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Immunity","Innate immunity","Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"25","RNA tissue specific nTPM":{"lymphoid tissue":"8.0","skin 1":"14.9","urinary bladder":"11.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"2.0","Collecting duct cells":"2.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"urothelial cancer":"17.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Bladder cancer":"8.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hippocampal formation":"3.0"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-5"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.86e-4"}},{"Gene":"PLA2G6","Gene synonym":["iPLA2","iPLA2beta","NBIA2","PARK14","PNPLA9"],"Ensembl":"ENSG00000184381","Gene description":"Phospholipase A2 group VI","Uniprot":["O60733"],"Chromosome":"22","Position":"38111495-38214778","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Chemotaxis","Lipid metabolism","Phospholipid metabolism"],"Molecular function":["Calmodulin-binding","Hydrolase"],"Disease involvement":["Disease variant","Dystonia","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"33.3","Spermatocytes":"36.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"3.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001171"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Centriolar satellite","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001171":"AB_1079145"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.29e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-4"}},{"Gene":"PLA2R1","Gene synonym":["CLEC13C","PLA2-R","PLA2G1R","PLA2IR"],"Ensembl":"ENSG00000153246","Gene description":"Phospholipase A2 receptor 1","Uniprot":["Q13018"],"Chromosome":"2","Position":"159932006-160062615","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"39.1","thyroid gland":"41.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Serous glandular cells":"121.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"9.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Podocytes","Liver - Hepatic stellate cells","Lung - Fibroblast_1","Skeletal muscle - Fibroblasts","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB068217","CAB068218"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"960000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB068217":"AB_2665660","CAB068218":"AB_2665661"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.08e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"}},{"Gene":"PLAAT2","Gene synonym":["FLJ20556","HRASLS2","PLAAT-2"],"Ensembl":"ENSG00000133328","Gene description":"Phospholipase A and acyltransferase 2","Uniprot":["Q9NWW9"],"Chromosome":"11","Position":"63552770-63563379","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Acyltransferase","Hydrolase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"67.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"56.1","Endometrial ciliated cells":"50.6","Ionocytes":"53.1","Proximal enterocytes":"92.1","Proximal tubular cells":"153.7","Respiratory ciliated cells":"118.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"memory B-cell":"17.3","naive B-cell":"8.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"B-cells":"17.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Myeloma":"35.1"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Colon - Colon enterocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058997"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA058997":"AB_2683874"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.87e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.27e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"}},{"Gene":"PLAAT3","Gene synonym":["AdPLA","H-REV107-1","HRASLS3","HREV107","HREV107-3","MGC118754.","PLA2G16","PLAAT-3"],"Ensembl":"ENSG00000176485","Gene description":"Phospholipase A and acyltransferase 3","Uniprot":["P53816"],"Chromosome":"11","Position":"63573195-63616883","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Host-virus interaction","Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"318.7","brain":"394.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"423.9","Granulosa cells":"500.2","Proximal tubular cells":"667.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"187.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"187.8","T-cells":"55.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011749","HPA058997"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA011749":null,"HPA058997":"AB_2683874"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.58e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.54e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"}},{"Gene":"PLAAT4","Gene synonym":["HRASLS4","PLAAT-4","RARRES3","RIG1","TIG3"],"Ensembl":"ENSG00000133321","Gene description":"Phospholipase A and acyltransferase 4","Uniprot":["Q9UL19"],"Chromosome":"11","Position":"63536808-63546462","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"381.5","Proximal enterocytes":"553.7","Proximal tubular cells":"1134.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"142.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.00e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.26e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"}},{"Gene":"PLAT","Gene synonym":[],"Ensembl":"ENSG00000104368","Gene description":"Plasminogen activator, tissue type","Uniprot":["P00750"],"Chromosome":"8","Position":"42174718-42207709","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","FDA approved drug targets","Plasma proteins","Predicted secreted proteins"],"Biological process":["Plasminogen activation"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"246.0","urinary bladder":"181.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"76.2","Basal respiratory cells":"135.4","Breast glandular cells":"100.4","Endometrial stromal cells":"103.1","Endothelial cells":"98.4","Fibroblasts":"92.8","Granulosa cells":"85.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"260.2"},"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Prostate - Urothelial cells","Testis - Sertoli cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003412","CAB009335"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":9900000,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"CAB009335":"AB_2237146","HPA003412":"AB_1858205"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.57e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.95e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"}},{"Gene":"PLAUR","Gene synonym":["CD87","UPAR","URKR"],"Ensembl":"ENSG00000011422","Gene description":"Plasminogen activator, urokinase receptor","Uniprot":["Q03405"],"Chromosome":"19","Position":"43646095-43670547","Protein class":["Cancer-related genes","CD markers","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"688.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"819.0","Langerhans cells":"2323.1","Macrophages":"691.5","monocytes":"1607.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1172.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1172.3","monocytes":"550.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050843","CAB073533"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4100000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB073533":null,"HPA050843":"AB_2681255"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.33e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.83e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"}},{"Gene":"PLB1","Gene synonym":["FLJ30866","PLB"],"Ensembl":"ENSG00000163803","Gene description":"Phospholipase B1","Uniprot":["Q6P1J6"],"Chromosome":"2","Position":"28457145-28644142","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Phospholipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"39.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"26.3","Extravillous trophoblasts":"31.4","Late spermatids":"18.7","Proximal enterocytes":"121.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"classical monocyte":"3.0","eosinophil":"3.0","intermediate monocyte":"4.4","myeloid DC":"5.7","neutrophil":"8.8","non-classical monocyte":"5.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"40","RNA blood lineage specific nTPM":{"dendritic cells":"5.7","granulocytes":"8.8","monocytes":"5.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Macrophages","Lung - Neutrophil_2","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"}},{"Gene":"PLCE1","Gene synonym":["KIAA1516","NPHS3","PLCE"],"Ensembl":"ENSG00000138193","Gene description":"Phospholipase C epsilon 1","Uniprot":["Q9P212"],"Chromosome":"10","Position":"93993931-94332823","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Guanine-nucleotide releasing factor","Hydrolase","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"67.4","Distal enterocytes":"79.8","Inhibitory neurons":"82.0","Muller glia cells":"71.3","Oligodendrocyte precursor cells":"117.9","Skeletal myocytes":"68.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Podocytes","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015597","HPA015598"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015597":"AB_1855321","HPA015598":"AB_1855322"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"}},{"Gene":"PLD3","Gene synonym":["HU-K4"],"Ensembl":"ENSG00000105223","Gene description":"Phospholipase D family member 3","Uniprot":["Q8IV08"],"Chromosome":"19","Position":"40348456-40380439","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response"],"Molecular function":["Exonuclease","Hydrolase","Nuclease"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"711.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"631.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"1727.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"1727.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Fibroblasts","Colon - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012800","CAB020812"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"450000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB020812":null,"HPA012800":"AB_1855330"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.44e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"}},{"Gene":"PLD4","Gene synonym":["C14orf175"],"Ensembl":"ENSG00000166428","Gene description":"Phospholipase D family member 4","Uniprot":["Q96BZ4"],"Chromosome":"14","Position":"104924713-104937761","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Exonuclease","Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"13.4","brain":"16.7","lymphoid tissue":"11.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"dendritic cells":"704.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"4.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"3621.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"3621.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"73","RNA cell line specific nTPM":{"Leukemia":"32.8","lymphoma":"31.9","Myeloma":"36.6"},"RNA tissue cell type enrichment":["Prostate - T-cells","Skin - Langerhans cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051512"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2900000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051512":"AB_2681515"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"}},{"Gene":"PLD5","Gene synonym":["FLJ40773"],"Ensembl":"ENSG00000180287","Gene description":"Phospholipase D family member 5","Uniprot":["Q8N7P1"],"Chromosome":"1","Position":"242082986-242524697","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"16.2","choroid plexus":"52.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Inhibitory neurons":"312.1","Oligodendrocyte precursor cells":"122.3","Oligodendrocytes":"214.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.7"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"16.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"5.7","Neuroblastoma":"4.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028389"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA028389":"AB_10602145"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"}},{"Gene":"PLD6","Gene synonym":[],"Ensembl":"ENSG00000179598","Gene description":"Phospholipase D family member 6","Uniprot":["Q8N2A8"],"Chromosome":"17","Position":"17200995-17206333","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Lipid degradation","Lipid metabolism","Meiosis","Spermatogenesis"],"Molecular function":["Endonuclease","Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"31.0","Spermatogonia":"28.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"5.8","NK-cells":"6.3","T-cells":"11.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049345"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049345":"AB_2680722"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"}},{"Gene":"PLEKHB1","Gene synonym":["KPL1","PHR1","PHRET1"],"Ensembl":"ENSG00000021300","Gene description":"Pleckstrin homology domain containing B1","Uniprot":["Q9UF11"],"Chromosome":"11","Position":"73646178-73662819","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"1531.3","choroid plexus":"728.4","retina":"758.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1173.6","Late spermatids":"199.6","Muller glia cells":"449.3","Rod photoreceptor cells":"392.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"59.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"83.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"83.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"48.5"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.02e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.99e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"}},{"Gene":"PLEKHB2","Gene synonym":["EVT2","FLJ20783"],"Ensembl":"ENSG00000115762","Gene description":"Pleckstrin homology domain containing B2","Uniprot":["Q96CS7"],"Chromosome":"2","Position":"131104847-131353709","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075014"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA075014":"AB_2732275"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.44e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.72e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"}},{"Gene":"PLEKHH3","Gene synonym":["FLJ21019"],"Ensembl":"ENSG00000068137","Gene description":"Pleckstrin homology, MyTH4 and FERM domain containing H3","Uniprot":["Q7Z736"],"Chromosome":"17","Position":"42667914-42676994","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"41.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"56.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046234"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA046234":"AB_2679597"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.62e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"}},{"Gene":"PLEKHN1","Gene synonym":["DKFZP434H2010"],"Ensembl":"ENSG00000187583","Gene description":"Pleckstrin homology domain containing N1","Uniprot":["Q494U1"],"Chromosome":"1","Position":"966482-975865","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"54.9","skin 1":"46.0","vagina":"24.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"20.2","Exocrine glandular cells":"23.2","Squamous epithelial cells":"41.9","Suprabasal keratinocytes":"72.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"24.0"},"RNA tissue cell type enrichment":["Prostate - Urothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031742"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA031742":"AB_10670704"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.97e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"PLET1","Gene synonym":["C11orf34"],"Ensembl":"ENSG00000188771","Gene description":"Placenta expressed transcript 1","Uniprot":["Q6UQ28"],"Chromosome":"11","Position":"112248153-112260860","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"1.7","Inhibitory neurons":"1.9","Oligodendrocytes":"5.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"1.8"},"Antibody":["HPA040237"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040237":"AB_10793960"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PLG","Gene synonym":[],"Ensembl":"ENSG00000122194","Gene description":"Plasminogen","Uniprot":["P00747"],"Chromosome":"6","Position":"160702238-160754097","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted secreted proteins"],"Biological process":["Blood coagulation","Fibrinolysis","Hemostasis","Tissue remodeling"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Thrombophilia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"liver":"2666.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatocytes":"1638.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"84","RNA cancer specific FPKM":{"liver cancer":"180.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"liver cancer":"2.2"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000668","CAB016678","HPA021602","HPA048823","HPA053770"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":140000000000,"Blood concentration - Conc. blood MS [pg\/L]":"45000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB000668":null,"CAB016678":"AB_1621208","HPA021602":"AB_1855453","HPA048823":"AB_2680532","HPA053770":"AB_2682256"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.22e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"}},{"Gene":"PLIN1","Gene synonym":["PLIN"],"Ensembl":"ENSG00000166819","Gene description":"Perilipin 1","Uniprot":["O60240"],"Chromosome":"15","Position":"89664367-89679427","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"adipose tissue":"956.3","breast":"463.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Hepatocytes":"55.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"breast cancer":"8.4","liver cancer":"2.3","pancreatic cancer":"2.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skin - Adipocytes (Skin)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024299","CAB033821","CAB037333"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"22000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"CAB033821":"AB_2252681","CAB037333":null,"HPA024299":"AB_1855467"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"}},{"Gene":"PLLP","Gene synonym":["PMLP","TM4SF11"],"Ensembl":"ENSG00000102934","Gene description":"Plasmolipin","Uniprot":["Q9Y342"],"Chromosome":"16","Position":"57248547-57284672","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"844.1","choroid plexus":"1086.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"164.8","Cholangiocytes":"167.5","Glandular and luminal cells":"146.8","Oligodendrocyte precursor cells":"134.3","Oligodendrocytes":"182.5","Proximal enterocytes":"154.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"naive CD4 T-cell":"14.5","naive CD8 T-cell":"5.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"T-cells":"14.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Liver - Hepatocytes","Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041862"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041862":"AB_2677712"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.80e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.21e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"}},{"Gene":"PLN","Gene synonym":["CMD1P","PLB"],"Ensembl":"ENSG00000198523","Gene description":"Phospholamban","Uniprot":["P26678"],"Chromosome":"6","Position":"118548296-118561716","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"1563.4","skeletal muscle":"507.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Cardiomyocytes":"4191.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"skin cancer":"4.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Colon - Smooth muscle cells","Heart muscle - Cardiomyocytes","Lung - Smooth muscle cells","Prostate - Smooth muscle cells","Skeletal muscle - Skeletal myocytes","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005597","HPA026900"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB005597":"AB_2252716","HPA026900":"AB_1855314"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.59e-4"}},{"Gene":"PLOD2","Gene synonym":["LH2"],"Ensembl":"ENSG00000152952","Gene description":"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2","Uniprot":["O00469"],"Chromosome":"3","Position":"146069440-146163653","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Dioxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"126.8","Extravillous trophoblasts":"150.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"318.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025898","HPA069126"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB025898":null,"HPA069126":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.97e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.64e-10"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.42e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.99e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.83e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-3"}},{"Gene":"PLP1","Gene synonym":["GPM6C","PLP","SPG2"],"Ensembl":"ENSG00000123560","Gene description":"Proteolipid protein 1","Uniprot":["P60201"],"Chromosome":"X","Position":"103773718-103792619","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary spastic paraplegia","Leukodystrophy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"7004.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"4552.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"22","RNA cancer specific FPKM":{"glioma":"160.5","melanoma":"75.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"skin cancer":"218.3"},"RNA tissue cell type enrichment":["Adipose visceral - Smooth muscle cells","Colon - Enteric glia cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004128"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004128":"AB_1079635"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"}},{"Gene":"PLP2","Gene synonym":["A4","A4-LSB","MGC126187"],"Ensembl":"ENSG00000102007","Gene description":"Proteolipid protein 2","Uniprot":["Q04941"],"Chromosome":"X","Position":"49171898-49175235","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"516.4","Suprabasal keratinocytes":"547.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042415"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"250000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042415":"AB_10796907"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.32e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.55e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"}},{"Gene":"PLPP1","Gene synonym":["LPP1","PAP-2a","PPAP2A"],"Ensembl":"ENSG00000067113","Gene description":"Phospholipid phosphatase 1","Uniprot":["O14494"],"Chromosome":"5","Position":"55424854-55534969","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"315.2","Endometrial stromal cells":"212.1","Leydig cells":"221.6","Prostatic glandular cells":"747.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"200.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"90.0"},"RNA tissue cell type enrichment":["Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033331","HPA047815"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB033331":"AB_2168044","HPA047815":"AB_2680164"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.77e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"}},{"Gene":"PLPP2","Gene synonym":["LPP2","PAP-2c","PPAP2C"],"Ensembl":"ENSG00000141934","Gene description":"Phospholipid phosphatase 2","Uniprot":["O43688"],"Chromosome":"19","Position":"281040-291403","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"223.3","Club cells":"239.4","Ductal cells":"326.7","Ionocytes":"255.4","Respiratory ciliated cells":"229.2","Rod photoreceptor cells":"246.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"3.2","MAIT T-cell":"6.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"41","RNA blood lineage specific nTPM":{"T-cells":"6.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Cholangiocyte","Lung - Respiratory ciliated cells","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055540","HPA058428"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA055540":"AB_2682839","HPA058428":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.55e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.21e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"}},{"Gene":"PLPP3","Gene synonym":["LPP3","PAP-2b","PPAP2B"],"Ensembl":"ENSG00000162407","Gene description":"Phospholipid phosphatase 3","Uniprot":["O14495"],"Chromosome":"1","Position":"56494761-56645301","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"362.5","Fibroblasts":"403.1","Leydig cells":"881.4","Peritubular cells":"311.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"168.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"memory B-cell":"2.4","naive B-cell":"2.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"2.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"64.2"},"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Prostate - Fibroblasts","Skin - Fibroblast_2","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072751"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA072751":"AB_2686555"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.59e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"}},{"Gene":"PLPP4","Gene synonym":["DPPL2","PPAPDC1","PPAPDC1A"],"Ensembl":"ENSG00000203805","Gene description":"Phospholipid phosphatase 4","Uniprot":["Q5VZY2"],"Chromosome":"10","Position":"120457227-120592065","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"12.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"144.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enteroendocrine cells","Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045188"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA045188":"AB_2679246"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"}},{"Gene":"PLPP5","Gene synonym":["DPPL1","HTPAP","PPAPDC1B"],"Ensembl":"ENSG00000147535","Gene description":"Phospholipid phosphatase 5","Uniprot":["Q8NEB5"],"Chromosome":"8","Position":"38263130-38269243","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"274.6","Prostatic glandular cells":"185.4","Serous glandular cells":"172.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"80.2","memory B-cell":"211.8","naive B-cell":"305.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"305.9","granulocytes":"80.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Stomach - Chief cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055777"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA055777":"AB_2682915"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.48e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.72e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.42e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.33e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"}},{"Gene":"PLPP6","Gene synonym":["FLJ46512","FLJ90191","PDP1","PPAPDC2"],"Ensembl":"ENSG00000205808","Gene description":"Phospholipid phosphatase 6","Uniprot":["Q8IY26"],"Chromosome":"9","Position":"4662294-4665258","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity","Lipid metabolism"],"Molecular function":["Hydrolase","Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"68.8","Late spermatids":"61.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018096"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA018096":"AB_1855609"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.99e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"}},{"Gene":"PLPP7","Gene synonym":["C9orf67","FLJ14662","MGC12921","NET39","PPAPDC3"],"Ensembl":"ENSG00000160539","Gene description":"Phospholipid phosphatase 7 (inactive)","Uniprot":["Q8NBV4"],"Chromosome":"9","Position":"131289459-131359022","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"heart muscle":"91.2","skeletal muscle":"210.1","tongue":"74.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"20.8","Cardiomyocytes":"47.3","Extravillous trophoblasts":"25.8","Horizontal cells":"15.4","Skeletal myocytes":"50.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"5.9","Rhabdoid":"5.6"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070252"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA070252":"AB_2686242"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-3"}},{"Gene":"PLPPR1","Gene synonym":["FLJ20300","LPPR1","MGC26189","PRG-3"],"Ensembl":"ENSG00000148123","Gene description":"Phospholipid phosphatase related 1","Uniprot":["Q8TBJ4"],"Chromosome":"9","Position":"101028727-101325135","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"12.8","kidney":"15.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"615.2","Oligodendrocytes":"257.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"11.1","liver cancer":"5.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"1.0"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Pancreas - Alpha cells","Skin - Eccrine sweat gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014760","HPA014968","HPA014979"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA014760":"AB_2669084","HPA014968":"AB_1855702","HPA014979":"AB_2669130"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.37e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"}},{"Gene":"PLPPR2","Gene synonym":["LPPR2","PRG-4"],"Ensembl":"ENSG00000105520","Gene description":"Phospholipid phosphatase related 2","Uniprot":["Q96GM1"],"Chromosome":"19","Position":"11355386-11365698","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"72.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"72.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048973","HPA077966"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA048973":"AB_2680580","HPA077966":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.45e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.82e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.46e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"}},{"Gene":"PLPPR3","Gene synonym":["FLJ11535","LPPR3","PRG-2","PRG2"],"Ensembl":"ENSG00000129951","Gene description":"Phospholipid phosphatase related 3","Uniprot":["Q6T4P5"],"Chromosome":"19","Position":"812488-821955","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"9.8","brain":"21.1","fallopian tube":"11.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"38.5","Respiratory ciliated cells":"32.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"26.4","Neuroblastoma":"17.5"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Lung - Respiratory ciliated cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052293","HPA057034"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA052293":"AB_2681787","HPA057034":"AB_2683316"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"}},{"Gene":"PLPPR4","Gene synonym":["KIAA0455","LPPR4","PHP1","PRG-1"],"Ensembl":"ENSG00000117600","Gene description":"Phospholipid phosphatase related 4","Uniprot":["Q7Z2D5"],"Chromosome":"1","Position":"99263953-99309590","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"23.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"116.2","Inhibitory neurons":"161.9","Melanocytes":"67.9","Microglial cells":"46.5","Oligodendrocyte precursor cells":"92.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"7.2","melanoma":"2.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Brain cancer":"4.5","Neuroblastoma":"14.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"}},{"Gene":"PLPPR5","Gene synonym":["LPPR5","PAP2","PAP2D","PRG5"],"Ensembl":"ENSG00000117598","Gene description":"Phospholipid phosphatase related 5","Uniprot":["Q32ZL2"],"Chromosome":"1","Position":"98890245-99005032","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"7.1","retina":"1.6","testis":"2.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Excitatory neurons":"55.6","Inhibitory neurons":"133.7","Oligodendrocyte precursor cells":"138.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"glioma":"2.7","renal cancer":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"11.6"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018072","HPA059085"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA018072":"AB_1854958","HPA059085":"AB_2732631"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.22e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"}},{"Gene":"PLSCR3","Gene synonym":[],"Ensembl":"ENSG00000187838","Gene description":"Phospholipid scramblase 3","Uniprot":["Q9NRY6"],"Chromosome":"17","Position":"7389727-7394842","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"5.9","Basal squamous epithelial cells":"16.1","Plasma cells":"6.4","Schwann cells":"12.4","Squamous epithelial cells":"10.8","T-cells":"9.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048387","HPA068609"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA048387":"AB_2680381","HPA068609":"AB_2686011"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"}},{"Gene":"PLSCR4","Gene synonym":[],"Ensembl":"ENSG00000114698","Gene description":"Phospholipid scramblase 4","Uniprot":["Q9NRQ2"],"Chromosome":"3","Position":"146192335-146251179","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"76.0","Astrocytes":"146.5","Endothelial cells":"78.4","Schwann cells":"87.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Heart muscle - Fibroblasts","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002276"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA002276":"AB_1855479"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.90e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-3"}},{"Gene":"PLSCR5","Gene synonym":[],"Ensembl":"ENSG00000231213","Gene description":"Phospholipid scramblase family member 5","Uniprot":["A0PG75"],"Chromosome":"3","Position":"146576555-146605346","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"6.2","testis cancer":"1.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"midbrain":"1.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047249"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047249":"AB_2679997"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PLVAP","Gene synonym":["FELS","gp68","PV-1","PV1"],"Ensembl":"ENSG00000130300","Gene description":"Plasmalemma vesicle associated protein","Uniprot":["Q9BX97"],"Chromosome":"19","Position":"17351450-17377342","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"436.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Adipocytes":"460.8","Endothelial cells":"409.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"plasmacytoid DC":"35.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"35.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"Leukemia":"10.6","lymphoma":"2.9","ovarian cancer":"7.3"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Stomach - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002279"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"53000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane","Centrosome"],"Antibody RRID":{"HPA002279":"AB_1079636"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"}},{"Gene":"PLXDC1","Gene synonym":["TEM3","TEM7"],"Ensembl":"ENSG00000161381","Gene description":"Plexin domain containing 1","Uniprot":["Q8IUK5"],"Chromosome":"17","Position":"39063313-39154394","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"48.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"277.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"13.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012805"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012805":"AB_1857893"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.15e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"}},{"Gene":"PLXDC2","Gene synonym":["FLJ14623","TEM7R"],"Ensembl":"ENSG00000120594","Gene description":"Plexin domain containing 2","Uniprot":["Q6UX71"],"Chromosome":"10","Position":"19816239-20289856","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Microglial cells":"1468.6","Oligodendrocytes":"443.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"57.5","intermediate monocyte":"33.4","myeloid DC":"36.0","neutrophil":"81.6","non-classical monocyte":"37.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"dendritic cells":"36.0","granulocytes":"81.6","monocytes":"57.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Kidney - Fibroblasts","Lung - Fibroblast_1","Prostate - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017268","HPA070793"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"720000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA017268":"AB_10965928","HPA070793":"AB_2686313"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"}},{"Gene":"PLXNA1","Gene synonym":["NOV","PLXN1"],"Ensembl":"ENSG00000114554","Gene description":"Plexin A1","Uniprot":["Q9UIW2"],"Chromosome":"3","Position":"126988594-127037392","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Alveolar cells type 1":"126.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007499","CAB012483"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB012483":null,"HPA007499":"AB_1079637"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.13e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.64e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"}},{"Gene":"PLXNA2","Gene synonym":["FLJ11751","FLJ30634","KIAA0463","OCT","PLXN2"],"Ensembl":"ENSG00000076356","Gene description":"Plexin A2","Uniprot":["O75051"],"Chromosome":"1","Position":"208022242-208244384","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"35.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"69.3","Astrocytes":"97.4","Excitatory neurons":"132.9","Horizontal cells":"98.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Heart muscle - Endothelial cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009763"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009763":"AB_2166388"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"}},{"Gene":"PLXNA3","Gene synonym":["6.3","Plxn3","PLXN4","SEX","XAP-6"],"Ensembl":"ENSG00000130827","Gene description":"Plexin A3","Uniprot":["P51805"],"Chromosome":"X","Position":"154458281-154477779","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058989"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"94000","Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA058989":"AB_2683872"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"}},{"Gene":"PLXNA4","Gene synonym":["DKFZp434G0625PRO34003","FAYV2820","KIAA1550","PLXNA4A","PLXNA4B"],"Ensembl":"ENSG00000221866","Gene description":"Plexin A4","Uniprot":["Q9HCM2"],"Chromosome":"7","Position":"132123332-132648688","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"13.8","brain":"29.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"65.1","Excitatory neurons":"231.9","Inhibitory neurons":"256.1","Oligodendrocyte precursor cells":"49.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.3"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"29.1","hippocampal formation":"26.0"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"2.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"2.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"13.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029919","HPA052141","HPA075592"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA029919":"AB_10671093","HPA052141":"AB_2681745","HPA075592":"AB_2732297"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"}},{"Gene":"PLXNB1","Gene synonym":["KIAA0407","PLXN5","SEP"],"Ensembl":"ENSG00000164050","Gene description":"Plexin B1","Uniprot":["O43157"],"Chromosome":"3","Position":"48403854-48430086","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"117.4","Respiratory ciliated cells":"76.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040586"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"95000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040586":"AB_10794034"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.03e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.60e-4"}},{"Gene":"PLXNB2","Gene synonym":["KIAA0315","MM1","PLEXB2"],"Ensembl":"ENSG00000196576","Gene description":"Plexin B2","Uniprot":["O15031"],"Chromosome":"22","Position":"50274979-50307646","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"261.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"21","RNA blood cell specific nTPM":{"classical monocyte":"11.1","intermediate monocyte":"16.4","myeloid DC":"8.3","non-classical monocyte":"21.2","plasmacytoid DC":"6.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"25","RNA blood lineage specific nTPM":{"dendritic cells":"8.3","monocytes":"21.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003100"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"78000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003100":"AB_1079638"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.37e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.75e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"}},{"Gene":"PLXNB3","Gene synonym":["PLEXB3","PLEXR","PLXN6"],"Ensembl":"ENSG00000198753","Gene description":"Plexin B3","Uniprot":["Q9ULL4"],"Chromosome":"X","Position":"153764196-153779346","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Neurogenesis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"210.2","intestine":"57.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"42.4","Oligodendrocytes":"68.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"57.3"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048046"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"390000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048046":"AB_2680239"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.13e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"}},{"Gene":"PLXNC1","Gene synonym":["CD232","VESPR"],"Ensembl":"ENSG00000136040","Gene description":"Plexin C1","Uniprot":["O60486"],"Chromosome":"12","Position":"94148577-94307675","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"55.8","Kupffer cells":"68.1","Macrophages":"64.5","Melanocytes":"168.9","monocytes":"92.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"24.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"16.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"16.4","monocytes":"8.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"32.5"},"RNA tissue cell type enrichment":["Skin - Melanocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066899"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA066899":"AB_2685743"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"}},{"Gene":"PLXND1","Gene synonym":["KIAA0620"],"Ensembl":"ENSG00000004399","Gene description":"Plexin D1","Uniprot":["Q9Y4D7"],"Chromosome":"3","Position":"129555214-129606676","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"99.3","Endothelial cells":"111.4","Hofbauer cells":"78.9","Kupffer cells":"137.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"10.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"107.6"},"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"amygdala":"36.6","basal ganglia":"33.1","cerebral cortex":"27.4","hippocampal formation":"26.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020819"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB020819":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.93e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"}},{"Gene":"PMEL","Gene synonym":["D12S53E","gp100","Pmel17","SI","SIL","SILV"],"Ensembl":"ENSG00000185664","Gene description":"Premelanosome protein","Uniprot":["P40967"],"Chromosome":"12","Position":"55954105-55973317","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Melanin biosynthesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"cervix":"80.5","endometrium 1":"32.2","skin 1":"115.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"61","RNA single cell type specific nTPM":{"Melanocytes":"2241.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"500","RNA cancer specific FPKM":{"melanoma":"2481.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"36","RNA cell line specific nTPM":{"skin cancer":"2959.2"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skin - Melanocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031649"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"11000000","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA031649":"AB_2673976"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"PMEPA1","Gene synonym":["STAG1","TMEPAI"],"Ensembl":"ENSG00000124225","Gene description":"Prostate transmembrane protein, androgen induced 1","Uniprot":["Q969W9"],"Chromosome":"20","Position":"57648392-57711536","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Signal transduction inhibitor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"110.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"291.1","dendritic cells":"262.7","Ductal cells":"345.7","Muller glia cells":"317.9","Prostatic glandular cells":"647.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"157.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"naive B-cell":"6.3","plasmacytoid DC":"23.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"B-cells":"6.3","dendritic cells":"23.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Colon - Enteric glia cells","Prostate - Prostate glandular cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072291"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA072291":"AB_2686509"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.45e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.73e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.87e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.60e-4"}},{"Gene":"PMIS2","Gene synonym":["IFITMD9"],"Ensembl":"ENSG00000283758","Gene description":"PMIS2 transmembrane protein","Uniprot":["A0A1W2PS18"],"Chromosome":"19","Position":"35586161-35587296","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"15.5","Late spermatids":"24.2"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"17","RNA brain regional specific nTPM":{"cerebellum":"1.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PML","Gene synonym":["MYL","RNF71","TRIM19"],"Ensembl":"ENSG00000140464","Gene description":"PML nuclear body scaffold","Uniprot":["P29590"],"Chromosome":"15","Position":"73994673-74047827","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Apoptosis","Biological rhythms","Host-virus interaction","Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"123.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells","Heart muscle - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008312","CAB010194","CAB016304"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB010194":"AB_2166848","CAB016304":"AB_628162","HPA008312":"AB_1079643"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.24e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.29e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.27e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"}},{"Gene":"PMP22","Gene synonym":["CMT1A","GAS3","HMSNIA","HNPP","Sp110"],"Ensembl":"ENSG00000109099","Gene description":"Peripheral myelin protein 22","Uniprot":["Q01453"],"Chromosome":"17","Position":"15229773-15272292","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Deafness","Dejerine-Sottas syndrome","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"348.0","Hofbauer cells":"503.1","Leydig cells":"343.0","Melanocytes":"574.7","Proximal enterocytes":"719.0","Schwann cells":"1074.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"32.2","eosinophil":"43.0","plasmacytoid DC":"23.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"dendritic cells":"23.8","granulocytes":"43.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Brain cancer":"146.7","Rhabdoid":"117.0","skin cancer":"226.1","testis cancer":"333.9"},"RNA tissue cell type enrichment":["Lung - Fibroblast_1"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"}},{"Gene":"PNCK","Gene synonym":["CaMK1b","MGC45419"],"Ensembl":"ENSG00000130822","Gene description":"Pregnancy up-regulated nonubiquitous CaM kinase","Uniprot":["Q6P2M8"],"Chromosome":"X","Position":"153669733-153689010","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"65.1","intestine":"81.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"43.9","Cone photoreceptor cells":"31.0","Excitatory neurons":"28.6","Extravillous trophoblasts":"75.1","Granulosa cells":"48.2","Ionocytes":"45.2","Syncytiotrophoblasts":"61.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"15.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"13.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Heart muscle - Cardiomyocytes","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007458"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA007458":"AB_1079644"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-3"}},{"Gene":"PNKD","Gene synonym":["BRP17","DKFZp564N1362","DYT8","FKSG19","FPD1","KIAA1184","KIPP1184","MGC31943","MR-1","MR-1S","PDC","PKND1","TAHCCP2"],"Ensembl":"ENSG00000127838","Gene description":"PNKD metallo-beta-lactamase domain containing","Uniprot":["Q8N490"],"Chromosome":"2","Position":"218270392-218346793","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"463.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Prostate - Prostate glandular cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010134","HPA017068"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA010134":"AB_1079645","HPA017068":"AB_1855495"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.13e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"}},{"Gene":"PNLDC1","Gene synonym":["dJ195P10.2","FLJ40240"],"Ensembl":"ENSG00000146453","Gene description":"PARN like, ribonuclease domain containing 1","Uniprot":["Q8NA58"],"Chromosome":"6","Position":"159800249-159820704","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Nonsense-mediated mRNA decay"],"Molecular function":["Exonuclease","Hydrolase","Nuclease","RNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"10.2","testis":"8.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"21.9","Late spermatids":"13.5","Respiratory ciliated cells":"8.3","Spermatocytes":"13.6","Spermatogonia":"14.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"4.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"2.1"},"RNA tissue cell type enrichment":["Pancreas - Ductal cells","Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052026"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052026":"AB_2681699"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"}},{"Gene":"PNPLA6","Gene synonym":["iPLA2delta","NTE","SPG39","sws"],"Ensembl":"ENSG00000032444","Gene description":"Patatin like phospholipase domain containing 6","Uniprot":["Q8IY17"],"Chromosome":"19","Position":"7534004-7561764","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Dwarfism","Hereditary spastic paraplegia","Hypogonadotropic hypogonadism","Intellectual disability","Neurodegeneration","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"71.7","Late spermatids":"102.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007522","HPA064773"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007522":"AB_1079649","HPA064773":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.51e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.53e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"}},{"Gene":"PNPLA7","Gene synonym":["C9orf111","FLJ31318","FLJ43070","FLJ44279","NTE-R1","NTEL1","RP11-48C7.2"],"Ensembl":"ENSG00000130653","Gene description":"Patatin like phospholipase domain containing 7","Uniprot":["Q6ZV29"],"Chromosome":"9","Position":"137459952-137550402","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"54.4","Excitatory neurons":"23.3","Inhibitory neurons":"21.0","Oligodendrocytes":"19.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"9.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.0","T-reg":"1.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"1.0","T-cells":"1.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"4.9"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009130"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA009130":"AB_2268411"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.24e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"}},{"Gene":"PNPLA8","Gene synonym":["IPLA2-2","IPLA2G","iPLA2gamma"],"Ensembl":"ENSG00000135241","Gene description":"Patatin like phospholipase domain containing 8","Uniprot":["Q9NP80"],"Chromosome":"7","Position":"108470417-108569666","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020083"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA020083":"AB_1851849"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.86e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"}},{"Gene":"PODN","Gene synonym":["MGC24995","PCAN","PODOCAN","SLRR5A"],"Ensembl":"ENSG00000174348","Gene description":"Podocan","Uniprot":["Q7Z5L7"],"Chromosome":"1","Position":"53062052-53085501","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Fibroblasts":"158.8","Leydig cells":"273.8","Peritubular cells":"262.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"gdT-cell":"5.1","memory CD8 T-cell":"1.4","naive CD8 T-cell":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"52","RNA blood lineage specific nTPM":{"T-cells":"5.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"3.6"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Heart muscle - Fibroblasts","Liver - Hepatic stellate cells","Lung - Fibroblast_2","Pancreas - Fibroblasts","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"910000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.54e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"}},{"Gene":"PODXL","Gene synonym":["Gp200","PC","PCLP"],"Ensembl":"ENSG00000128567","Gene description":"Podocalyxin like","Uniprot":["O00592"],"Chromosome":"7","Position":"131500262-131558217","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"96.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"151.5","Endothelial cells":"192.1","Glandular and luminal cells":"100.5","Microglial cells":"90.3","Rod photoreceptor cells":"183.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"testis cancer":"640.8"},"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Kidney - Podocytes","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Stomach - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002110","CAB016169","HPA045507","CAB062558","CAB068219","CAB068220"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"33000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane","Centriolar satellite"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB016169":"AB_628165","CAB062558":"AB_2665627","CAB068219":"AB_2665618","CAB068220":"AB_2665619","HPA002110":"AB_1855512","HPA045507":"AB_2679356"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.89e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"}},{"Gene":"PODXL2","Gene synonym":["endoglycan","PODLX2"],"Ensembl":"ENSG00000114631","Gene description":"Podocalyxin like 2","Uniprot":["Q9NZ53"],"Chromosome":"3","Position":"127629185-127672802","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"65.6","pituitary gland":"59.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"89.9","Cone photoreceptor cells":"75.8","Early spermatids":"83.0","Horizontal cells":"84.6","Late spermatids":"147.4","Spermatogonia":"90.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB024934","HPA042265"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB024934":null,"HPA042265":"AB_2677920"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"}},{"Gene":"POFUT2","Gene synonym":["C21orf80","FUT13","KIAA0958"],"Ensembl":"ENSG00000186866","Gene description":"Protein O-fucosyltransferase 2","Uniprot":["Q9Y2G5"],"Chromosome":"21","Position":"45263928-45287898","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Fucose metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"44.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044297"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044297":"AB_10965176"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.55e-7"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.66e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"}},{"Gene":"POLB","Gene synonym":[],"Ensembl":"ENSG00000070501","Gene description":"DNA polymerase beta","Uniprot":["P06746"],"Chromosome":"8","Position":"42338454-42371808","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","DNA replication","DNA synthesis"],"Molecular function":["DNA-binding","DNA-directed DNA polymerase","Lyase","Nucleotidyltransferase","Transferase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"dendritic cells":"257.2","Early spermatids":"261.6","Late spermatids":"159.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011616","HPA049104","HPA069013"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB011616":"AB_731977","HPA049104":"AB_2680632","HPA069013":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.46e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.65e-4"}},{"Gene":"POLDIP3","Gene synonym":["KIAA1649","PDIP3","PDIP46","SKAR"],"Ensembl":"ENSG00000100227","Gene description":"DNA polymerase delta interacting protein 3","Uniprot":["Q9BY77"],"Chromosome":"22","Position":"42583721-42614962","Protein class":["Predicted intracellular proteins"],"Biological process":["mRNA transport","Translation regulation","Transport"],"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Late spermatids":"491.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018419","HPA048790"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear speckles","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytoplasmic bodies"],"Antibody RRID":{"HPA018419":"AB_1856928","HPA048790":"AB_2680522"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.79e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"}},{"Gene":"POLI","Gene synonym":["RAD30B","RAD3OB"],"Ensembl":"ENSG00000101751","Gene description":"DNA polymerase iota","Uniprot":["Q9UNA4"],"Chromosome":"18","Position":"54269517-54321266","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","DNA replication","DNA synthesis"],"Molecular function":["DNA-binding","DNA-directed DNA polymerase","Mutator protein","Nucleotidyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"153.2","Spermatocytes":"76.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012000","HPA064696"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytoplasmic bodies"],"Antibody RRID":{"HPA012000":"AB_1847786","HPA064696":"AB_2685325"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"}},{"Gene":"POLQ","Gene synonym":["POLH"],"Ensembl":"ENSG00000051341","Gene description":"DNA polymerase theta","Uniprot":["O75417"],"Chromosome":"3","Position":"121431427-121546641","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-directed DNA polymerase","Nucleotidyltransferase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"6.0","lymphoid tissue":"4.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"15.8","Excitatory neurons":"9.4","Granulosa cells":"12.4","Inhibitory neurons":"7.7","Plasma cells":"14.4","Spermatocytes":"7.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Mitotic cells (Colon)","Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Thyroid - Mitotic cells (Thyroid)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"2.5"},"Antibody":["HPA053359"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA053359":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.46e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"}},{"Gene":"POLR1E","Gene synonym":["FLJ13390","FLJ13970","PAF53","PRAF1","RPA49"],"Ensembl":"ENSG00000137054","Gene description":"RNA polymerase I subunit E","Uniprot":["Q9GZS1"],"Chromosome":"9","Position":"37485948-37503697","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","RNA polymerase related proteins"],"Biological process":["Transcription"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022527","HPA052400"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA022527":"AB_1854924","HPA052400":"AB_2681815"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.27e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"}},{"Gene":"POLR2H","Gene synonym":["RPB8"],"Ensembl":"ENSG00000163882","Gene description":"RNA polymerase II, I and III subunit H","Uniprot":["P52434"],"Chromosome":"3","Position":"184361718-184368596","Protein class":["Metabolic proteins","Predicted intracellular proteins","RNA polymerase related proteins"],"Biological process":["Transcription"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037745","HPA055813"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA037745":"AB_10672914","HPA055813":"AB_2797254"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.01e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.65e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"}},{"Gene":"POM121","Gene synonym":["DKFZP586G1822","DKFZP586P2220","KIAA0618","POM121A"],"Ensembl":"ENSG00000196313","Gene description":"POM121 transmembrane nucleoporin","Uniprot":["Q96HA1"],"Chromosome":"7","Position":"72879365-72951440","Protein class":["Metabolic proteins","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003710","HPA043809","HPA049817"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB003710":null,"HPA043809":"AB_2678680","HPA049817":"AB_2680896"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"}},{"Gene":"POM121C","Gene synonym":[],"Ensembl":"ENSG00000272391","Gene description":"POM121 transmembrane nucleoporin C","Uniprot":["A8CG34"],"Chromosome":"7","Position":"75416786-75486299","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043809","HPA049817"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA043809":"AB_2678680","HPA049817":"AB_2680896"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"}},{"Gene":"POMGNT1","Gene synonym":["FLJ20277","LGMD2O","MEB","MGAT1.2"],"Ensembl":"ENSG00000085998","Gene description":"Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)","Uniprot":["Q8WZA1"],"Chromosome":"1","Position":"46188682-46220305","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Limb-girdle muscular dystrophy","Lissencephaly","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044518"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044518":"AB_10795985"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.52e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.27e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"}},{"Gene":"POMK","Gene synonym":["FLJ23356","SgK196"],"Ensembl":"ENSG00000185900","Gene description":"Protein O-mannose kinase","Uniprot":["Q9H5K3"],"Chromosome":"8","Position":"43093498-43131180","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Limb-girdle muscular dystrophy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013321"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013321":"AB_2668809"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"}},{"Gene":"POMT1","Gene synonym":["LGMD2K"],"Ensembl":"ENSG00000130714","Gene description":"Protein O-mannosyltransferase 1","Uniprot":["Q9Y6A1"],"Chromosome":"9","Position":"131502789-131523806","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant","Dystroglycanopathy","Limb-girdle muscular dystrophy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"60.5","Spermatocytes":"63.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065252"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA065252":"AB_2685445"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.90e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.68e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"}},{"Gene":"POMT2","Gene synonym":["LGMD2N"],"Ensembl":"ENSG00000009830","Gene description":"Protein O-mannosyltransferase 2","Uniprot":["Q9UKY4"],"Chromosome":"14","Position":"77274956-77320883","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Dystroglycanopathy","Limb-girdle muscular dystrophy","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"37.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"26.3","Oligodendrocytes":"28.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003663"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA003663":"AB_1079655"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.40e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"}},{"Gene":"PON2","Gene synonym":[],"Ensembl":"ENSG00000105854","Gene description":"Paraoxonase 2","Uniprot":["Q15165"],"Chromosome":"7","Position":"95404862-95435329","Protein class":["Candidate cardiovascular disease genes","Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"258.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"330.9","Extravillous trophoblasts":"355.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"33.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025430","HPA029193"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025430":null,"HPA029193":"AB_10602148"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.43e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.30e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"}},{"Gene":"POPDC2","Gene synonym":["POP2"],"Ensembl":"ENSG00000121577","Gene description":"Popeye domain containing 2","Uniprot":["Q9HBU9"],"Chromosome":"3","Position":"119636457-119665324","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"405.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cardiomyocytes":"249.1","Skeletal myocytes":"65.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"4.5","testis cancer":"2.5"},"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Prostate - Smooth muscle cells","Skin - Smooth muscle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024255"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024255":"AB_1855545"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"}},{"Gene":"POPDC3","Gene synonym":["bA355M14.1","MGC22671","POP3"],"Ensembl":"ENSG00000132429","Gene description":"Popeye domain containing 3","Uniprot":["Q9HBV1"],"Chromosome":"6","Position":"105157900-105180014","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"23.0","skeletal muscle":"96.3","tongue":"29.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"58.0","Early spermatids":"77.1","Excitatory neurons":"16.3","Late spermatids":"34.5","Pancreatic endocrine cells":"18.9","Skeletal myocytes":"46.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Prostate - Smooth muscle cells","Stomach - Chief cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012514"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA012514":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.43e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.79e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"}},{"Gene":"POR","Gene synonym":["CYPOR","FLJ26468"],"Ensembl":"ENSG00000127948","Gene description":"Cytochrome p450 oxidoreductase","Uniprot":["P16435"],"Chromosome":"7","Position":"75899200-75986855","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Congenital adrenal hyperplasia","Craniosynostosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"313.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"421.3","Ionocytes":"320.1","Proximal enterocytes":"282.0","Theca cells":"454.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004372","HPA010136"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB004372":"AB_627391","HPA010136":"AB_1079657"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.54e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"}},{"Gene":"PORCN","Gene synonym":["DHOF","MG61","por","PORC","PPN"],"Ensembl":"ENSG00000102312","Gene description":"Porcupine O-acyltransferase","Uniprot":["Q9H237"],"Chromosome":"X","Position":"48508962-48520814","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"37.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"64.6","Club cells":"29.8","Ionocytes":"40.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049215","HPA058413"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049215":null,"HPA058413":"AB_2683711"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"}},{"Gene":"POT1","Gene synonym":["DKFZp586D211","hPot1"],"Ensembl":"ENSG00000128513","Gene description":"Protection of telomeres 1","Uniprot":["Q9NUX5"],"Chromosome":"7","Position":"124822386-124929983","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"40.6","Oligodendrocytes":"63.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068538"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA068538":"AB_2686001"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"}},{"Gene":"POU2F2","Gene synonym":["OCT2","OTF2"],"Ensembl":"ENSG00000028277","Gene description":"POU class 2 homeobox 2","Uniprot":["P09086"],"Chromosome":"19","Position":"42086110-42196585","Protein class":["Cancer-related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"52.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"254.1","Kupffer cells":"109.0","Langerhans cells":"139.6","Macrophages":"109.5","monocytes":"315.9","Plasma cells":"115.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"94.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"lymphoma":"97.6","Myeloma":"30.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002513","HPA049056","HPA062096","HPA064404","HPA073998"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB002513":"AB_442118","HPA049056":"AB_2732550","HPA062096":"AB_2684681","HPA064404":"AB_2685259","HPA073998":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.57e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"}},{"Gene":"POU6F2","Gene synonym":["RPF-1"],"Ensembl":"ENSG00000106536","Gene description":"POU class 6 homeobox 2","Uniprot":["P78424"],"Chromosome":"7","Position":"38977909-39493095","Protein class":["Disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"125.3","Excitatory neurons":"464.7","Oligodendrocyte precursor cells":"274.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"1.5"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"}},{"Gene":"PPAN-P2RY11","Gene synonym":[],"Ensembl":"ENSG00000243207","Gene description":"PPAN-P2RY11 readthrough","Uniprot":[],"Chromosome":"19","Position":"10106223-10114780","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"B-cells":"9.3","Basal squamous epithelial cells":"13.4","Erythroid cells":"8.7","Gastric mucus-secreting cells":"11.9","Plasma cells":"10.0","Squamous epithelial cells":"17.7","T-cells":"5.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014232"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014232":"AB_1854883"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"}},{"Gene":"PPCS","Gene synonym":["FLJ11838"],"Ensembl":"ENSG00000127125","Gene description":"Phosphopantothenoylcysteine synthetase","Uniprot":["Q9HAB8"],"Chromosome":"1","Position":"42456117-42473385","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Ligase"],"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"366.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031361","HPA031363"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA031361":"AB_10602150","HPA031363":"AB_2673844"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.96e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"}},{"Gene":"PPDPF","Gene synonym":["C20orf149","dJ697K14.9","exdpf"],"Ensembl":"ENSG00000125534","Gene description":"Pancreatic progenitor cell differentiation and proliferation factor","Uniprot":["Q9H3Y8"],"Chromosome":"20","Position":"63520765-63522206","Protein class":["Predicted intracellular proteins"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"3231.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"26.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"26.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040929"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Microtubules"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm","Microtubules"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA040929":"AB_10794155"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"}},{"Gene":"PPEF1","Gene synonym":["PPEF","PPP7CA"],"Ensembl":"ENSG00000086717","Gene description":"Protein phosphatase with EF-hand domain 1","Uniprot":["O14829"],"Chromosome":"X","Position":"18675909-18827921","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"5.8","testis":"14.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"57.3","Late spermatids":"138.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"3.8","Uterine cancer":"1.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034577"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA034577":"AB_10602817"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"}},{"Gene":"PPFIA1","Gene synonym":["LIP.1","LIPRIN"],"Ensembl":"ENSG00000131626","Gene description":"PTPRF interacting protein alpha 1","Uniprot":["Q13136"],"Chromosome":"11","Position":"70270690-70385312","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"166.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017032","HPA042271"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Focal adhesion sites","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Focal adhesion sites"],"Antibody RRID":{"CAB017032":null,"HPA042271":"AB_2677923"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.58e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.76e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"}},{"Gene":"PPIL2","Gene synonym":["CYC4","Cyp-60","UBOX7"],"Ensembl":"ENSG00000100023","Gene description":"Peptidylprolyl isomerase like 2","Uniprot":["Q13356"],"Chromosome":"22","Position":"21666000-21700015","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035344","HPA055637"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA035344":"AB_10672863","HPA055637":"AB_2682869"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"}},{"Gene":"PPIL3","Gene synonym":["CyPJ"],"Ensembl":"ENSG00000240344","Gene description":"Peptidylprolyl isomerase like 3","Uniprot":["Q9H2H8"],"Chromosome":"2","Position":"200870907-200889303","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Isomerase","Rotamase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040765","HPA062187"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA040765":"AB_2677125","HPA062187":"AB_2684706"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.19e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"}},{"Gene":"PPIL6","Gene synonym":["bA425D10.6","dJ919F19.1","MGC41939","RSPH12"],"Ensembl":"ENSG00000185250","Gene description":"Peptidylprolyl isomerase like 6","Uniprot":["Q8IXY8"],"Chromosome":"6","Position":"109390215-109441171","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"35.6","testis":"18.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"437.0","Endometrial ciliated cells":"226.3","Late spermatids":"91.0","Respiratory ciliated cells":"164.6","Spermatocytes":"90.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036717","HPA058165"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA036717":"AB_10671969","HPA058165":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"}},{"Gene":"PPIP5K1","Gene synonym":["HISPPD2A","IPS1","KIAA0377","VIP1"],"Ensembl":"ENSG00000168781","Gene description":"Diphosphoinositol pentakisphosphate kinase 1","Uniprot":["Q6PFW1"],"Chromosome":"15","Position":"43533462-43590253","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"24.1","Excitatory neurons":"45.9","Inhibitory neurons":"36.7","Rod photoreceptor cells":"35.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"45.4"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039380"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039380":"AB_10673528"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.57e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.14e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-3"}},{"Gene":"PPIP5K2","Gene synonym":["CFAP160","DFNB100","HISPPD1","KIAA0433","VIP2"],"Ensembl":"ENSG00000145725","Gene description":"Diphosphoinositol pentakisphosphate kinase 2","Uniprot":["O43314"],"Chromosome":"5","Position":"103120149-103212799","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"157.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037895","HPA038442"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA037895":"AB_2675724","HPA038442":"AB_10673173"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"}},{"Gene":"PPM1D","Gene synonym":["PP2C-DELTA","Wip1"],"Ensembl":"ENSG00000170836","Gene description":"Protein phosphatase, Mg2+\/Mn2+ dependent 1D","Uniprot":["O15297"],"Chromosome":"17","Position":"60600183-60666280","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"76.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022277","HPA061848"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA022277":"AB_1858839","HPA061848":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.52e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"}},{"Gene":"PPM1J","Gene synonym":["DKFZp434P1514","FLJ35951","MGC19531","PP2Czeta","PPP2CZ"],"Ensembl":"ENSG00000155367","Gene description":"Protein phosphatase, Mg2+\/Mn2+ dependent 1J","Uniprot":["Q5JR12"],"Chromosome":"1","Position":"112709994-112715477","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"epididymis":"18.8","skeletal muscle":"68.4","skin 1":"18.1","testis":"63.8","tongue":"25.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"64.9","Early spermatids":"93.5","Late spermatids":"273.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"plasmacytoid DC":"67.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"dendritic cells":"67.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes","Skin - Keratinocyte (other)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"olfactory bulb":"27.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046045"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046045":"AB_2679516"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-4"}},{"Gene":"PPM1L","Gene synonym":["PP2CE"],"Ensembl":"ENSG00000163590","Gene description":"Protein phosphatase, Mg2+\/Mn2+ dependent 1L","Uniprot":["Q5SGD2"],"Chromosome":"3","Position":"160755602-161078902","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"122.7","Excitatory neurons":"339.7","Inhibitory neurons":"171.6","Oligodendrocyte precursor cells":"106.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"4.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019891","HPA019953"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"26000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA019891":"AB_1855631","HPA019953":"AB_2170360"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.90e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"}},{"Gene":"PPM1M","Gene synonym":["FLJ32332","PP2Ceta"],"Ensembl":"ENSG00000164088","Gene description":"Protein phosphatase, Mg2+\/Mn2+ dependent 1M","Uniprot":["Q96MI6"],"Chromosome":"3","Position":"52245759-52250599","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"49.5","Kupffer cells":"43.9","Macrophages":"31.0","monocytes":"31.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036905","HPA062291"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA036905":"AB_10602818","HPA062291":"AB_2684740"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.73e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.69e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"}},{"Gene":"PPOX","Gene synonym":["PPO","VP"],"Ensembl":"ENSG00000143224","Gene description":"Protoporphyrinogen oxidase","Uniprot":["P50336"],"Chromosome":"1","Position":"161166056-161178013","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Heme biosynthesis","Porphyrin biosynthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"60.0","Respiratory ciliated cells":"76.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030123"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA030123":"AB_10603987"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.89e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"}},{"Gene":"PPP1CC","Gene synonym":["PP1C","PP1gamma"],"Ensembl":"ENSG00000186298","Gene description":"Protein phosphatase 1 catalytic subunit gamma","Uniprot":["P36873"],"Chromosome":"12","Position":"110719680-110742939","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Carbohydrate metabolism","Cell cycle","Cell division","Glycogen metabolism"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"618.8","Late spermatids":"936.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022645","CAB079921"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2800000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB022645":null,"CAB079921":"AB_11153939"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.44e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.75e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"}},{"Gene":"PPP1R13B","Gene synonym":["ASPP1","KIAA0771","p53BP2-like","p85"],"Ensembl":"ENSG00000088808","Gene description":"Protein phosphatase 1 regulatory subunit 13B","Uniprot":["Q96KQ4"],"Chromosome":"14","Position":"103733195-103847575","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"104.6","Granulosa cells":"81.2","Inhibitory neurons":"103.6","Late spermatids":"80.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006394","CAB015454"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB015454":"AB_2252775","HPA006394":"AB_1079668"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.41e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.28e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"}},{"Gene":"PPP1R3A","Gene synonym":["GM","PPP1R3"],"Ensembl":"ENSG00000154415","Gene description":"Protein phosphatase 1 regulatory subunit 3A","Uniprot":["Q16821"],"Chromosome":"7","Position":"113876777-114075920","Protein class":["Disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Carbohydrate metabolism","Glycogen metabolism"],"Molecular function":null,"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"64","RNA tissue specific nTPM":{"heart muscle":"40.8","skeletal muscle":"152.9","tongue":"104.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Cardiomyocytes":"229.8","Skeletal myocytes":"197.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"12","RNA mouse brain regional specific nTPM":{"thalamus":"1.1"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070440","HPA073138"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA070440":null,"HPA073138":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PPP1R3F","Gene synonym":["Hb2E"],"Ensembl":"ENSG00000049769","Gene description":"Protein phosphatase 1 regulatory subunit 3F","Uniprot":["Q6ZSY5"],"Chromosome":"X","Position":"49269793-49301461","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"27.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"33.6","Horizontal cells":"33.3","Oligodendrocytes":"32.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"T-reg":"9.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"T-cells":"9.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000244","HPA000918"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA000244":"AB_2665949","HPA000918":"AB_2268692"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"}},{"Gene":"PPP2R1A","Gene synonym":["PP2A-Aalpha","PP2AA","PR65A"],"Ensembl":"ENSG00000105568","Gene description":"Protein phosphatase 2 scaffold subunit Aalpha","Uniprot":["P30153"],"Chromosome":"19","Position":"52190048-52229518","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Chromosome partition","Host-virus interaction"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Skin - Keratinocyte (other)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018599"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB018599":"AB_628178"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.76e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.50e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-2"}},{"Gene":"PPP4R3B","Gene synonym":["FLFL2","FLJ31474","KIAA1387","PSY2","SMEK2"],"Ensembl":"ENSG00000275052","Gene description":"Protein phosphatase 4 regulatory subunit 3B","Uniprot":["Q5MIZ7"],"Chromosome":"2","Position":"55547292-55618880","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001233","CAB017185"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear speckles","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nuclear speckles"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"CAB017185":null,"HPA001233":"AB_1080033"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"}},{"Gene":"PPT1","Gene synonym":["CLN1","INCL","PPT"],"Ensembl":"ENSG00000131238","Gene description":"Palmitoyl-protein thioesterase 1","Uniprot":["P50897"],"Chromosome":"1","Position":"40072710-40097260","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"286.7","Langerhans cells":"346.9","Macrophages":"246.2","Schwann cells":"216.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"1254.3","eosinophil":"624.2","intermediate monocyte":"1006.3","myeloid DC":"1091.1","neutrophil":"683.9","non-classical monocyte":"815.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"1091.1","granulocytes":"683.9","monocytes":"1254.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021546"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA021546":"AB_1855667"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.98e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"}},{"Gene":"PRAF2","Gene synonym":["JM4","Yip6a"],"Ensembl":"ENSG00000243279","Gene description":"PRA1 domain family member 2","Uniprot":["O60831"],"Chromosome":"X","Position":"49071161-49074002","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"163.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002859","HPA005504","CAB011655"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB011655":null,"HPA002859":"AB_1079672","HPA005504":"AB_2667340"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.42e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.66e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.81e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.88e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.83e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"}},{"Gene":"PRCP","Gene synonym":["HUMPCP","PCP"],"Ensembl":"ENSG00000137509","Gene description":"Prolylcarboxypeptidase","Uniprot":["P42785"],"Chromosome":"11","Position":"82822936-82970584","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Carboxypeptidase","Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endothelial cells":"190.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017065","HPA071115"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"42000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA017065":"AB_1855676","HPA071115":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.65e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"}},{"Gene":"PREB","Gene synonym":["SEC12"],"Ensembl":"ENSG00000138073","Gene description":"Prolactin regulatory element binding","Uniprot":["Q9HCU5"],"Chromosome":"2","Position":"27130756-27134666","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["ER-Golgi transport","Protein transport","Transcription","Transcription regulation","Transport"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"119.0","Syncytiotrophoblasts":"87.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013582","HPA014133"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA013582":"AB_1855694","HPA014133":"AB_1855695"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"}},{"Gene":"PRIMA1","Gene synonym":["PRIMA"],"Ensembl":"ENSG00000175785","Gene description":"Proline rich membrane anchor 1","Uniprot":["Q86XR5"],"Chromosome":"14","Position":"93718298-93788485","Protein class":["Predicted membrane proteins"],"Biological process":["Neurotransmitter degradation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"53.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Muller glia cells":"34.6","Oligodendrocytes":"51.7","Schwann cells":"122.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"11.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"5.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"18.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046671","HPA060047"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA046671":"AB_2679744","HPA060047":"AB_2684194"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.62e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"}},{"Gene":"PRKAA1","Gene synonym":["AMPKa1"],"Ensembl":"ENSG00000132356","Gene description":"Protein kinase AMP-activated catalytic subunit alpha 1","Uniprot":["Q13131"],"Chromosome":"5","Position":"40759379-40798374","Protein class":["Enzymes","FDA approved drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Biological rhythms","Cholesterol biosynthesis","Cholesterol metabolism","Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism","Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Chromatin regulator","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"276.4","Late spermatids":"493.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005050","HPA035409","HPA064946"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB005050":"AB_562037","HPA035409":"AB_2674613","HPA064946":"AB_2685390"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"}},{"Gene":"PRKAA2","Gene synonym":["AMPK","AMPKa2","PRKAA"],"Ensembl":"ENSG00000162409","Gene description":"Protein kinase AMP-activated catalytic subunit alpha 2","Uniprot":["P54646"],"Chromosome":"1","Position":"56645314-56715335","Protein class":["Enzymes","FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy","Biological rhythms","Cholesterol biosynthesis","Cholesterol metabolism","Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism","Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Chromatin regulator","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"40.8","skeletal muscle":"38.7","tongue":"36.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"492.7","Excitatory neurons":"107.9","Inhibitory neurons":"116.3","Rod photoreceptor cells":"127.0","Skeletal myocytes":"225.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"5.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044540"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA044540":"AB_2678977"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.80e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.30e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.95e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"}},{"Gene":"PRKAG1","Gene synonym":[],"Ensembl":"ENSG00000181929","Gene description":"Protein kinase AMP-activated non-catalytic subunit gamma 1","Uniprot":["P54619"],"Chromosome":"12","Position":"49002274-49018807","Protein class":["FDA approved drug targets","Predicted intracellular proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077805"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA077805":"AB_2686855"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.84e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"}},{"Gene":"PRKD1","Gene synonym":["PKC-mu","PKCM","PKD","PRKCM"],"Ensembl":"ENSG00000184304","Gene description":"Protein kinase D1","Uniprot":["Q15139"],"Chromosome":"14","Position":"29576479-30191898","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Angiogenesis","Apoptosis","Differentiation","Immunity","Inflammatory response","Innate immunity","Neurogenesis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"350.8","Excitatory neurons":"145.4","Inhibitory neurons":"167.7","Microglial cells":"86.7","Oligodendrocyte precursor cells":"374.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"10.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"19.7"},"RNA tissue cell type enrichment":["Breast - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018367","HPA029834"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB018367":"AB_2253119","HPA029834":"AB_10602821"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.44e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.91e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"}},{"Gene":"PRKD2","Gene synonym":["DKFZP586E0820","HSPC187","PKD2"],"Ensembl":"ENSG00000105287","Gene description":"Protein kinase D2","Uniprot":["Q9BZL6"],"Chromosome":"19","Position":"46674275-46717127","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Angiogenesis","Cell adhesion","Immunity"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Colon - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021490","HPA056727"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA021490":"AB_1855708","HPA056727":"AB_2683217"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.15e-4"}},{"Gene":"PRKD3","Gene synonym":["EPK2","PRKCN"],"Ensembl":"ENSG00000115825","Gene description":"Protein kinase D3","Uniprot":["O94806"],"Chromosome":"2","Position":"37250502-37324833","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"120.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029529"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029529":"AB_10602082"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.84e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"}},{"Gene":"PRLHR","Gene synonym":["GPR10","PrRPR"],"Ensembl":"ENSG00000119973","Gene description":"Prolactin releasing hormone receptor","Uniprot":["P49683"],"Chromosome":"10","Position":"118589997-118595648","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"5.2","brain":"12.7","pituitary gland":"6.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Granulosa cells":"7.4","Horizontal cells":"2.6","Inhibitory neurons":"2.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"1.4","prostate cancer":"1.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"1.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039361"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039361":"AB_10673527"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"PRLR","Gene synonym":[],"Ensembl":"ENSG00000113494","Gene description":"Prolactin receptor","Uniprot":["P16471"],"Chromosome":"5","Position":"35048756-35230487","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"choroid plexus":"781.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"59.7","Breast glandular cells":"72.3","Endometrial stromal cells":"109.1","Granulosa cells":"92.6","Proximal tubular cells":"47.1","Syncytiotrophoblasts":"65.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"breast cancer":"20.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"breast cancer":"32.7"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"}},{"Gene":"PRMT2","Gene synonym":["HRMT1L1","MGC111373"],"Ensembl":"ENSG00000160310","Gene description":"Protein arginine methyltransferase 2","Uniprot":["P55345"],"Chromosome":"21","Position":"46635595-46665124","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"365.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018976","HPA029591"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA018976":"AB_1855719","HPA029591":"AB_10601250"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"}},{"Gene":"PRND","Gene synonym":["dJ1068H6.4","DOPPEL","DPL","PrPLP"],"Ensembl":"ENSG00000171864","Gene description":"Prion like protein doppel","Uniprot":["Q9UKY0"],"Chromosome":"20","Position":"4721909-4728460","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Fertilization"],"Molecular function":["Prion"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"choroid plexus":"31.3","testis":"70.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Sertoli cells":"146.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Rhabdoid":"4.8"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043373"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043373":"AB_2678450"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"}},{"Gene":"PRNP","Gene synonym":["AltPrP","CD230","CJD","GSS","PRIP","PRP"],"Ensembl":"ENSG00000171867","Gene description":"Prion protein","Uniprot":["P04156"],"Chromosome":"20","Position":"4686350-4701590","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell cycle","Growth arrest"],"Molecular function":["Prion"],"Disease involvement":["Amyloidosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Schwann cells":"415.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"875.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"875.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042754","HPA043398"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5100000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Nuclear membrane","Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA042754":"AB_10964203","HPA043398":"AB_2678461"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.96e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.41e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"}},{"Gene":"PROC","Gene synonym":[],"Ensembl":"ENSG00000115718","Gene description":"Protein C, inactivator of coagulation factors Va and VIIIa","Uniprot":["P04070"],"Chromosome":"2","Position":"127418427-127429242","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Thrombophilia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"40","RNA tissue specific nTPM":{"liver":"598.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"343.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"22","RNA cancer specific FPKM":{"liver cancer":"118.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"plasmacytoid DC":"59.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"59.7"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"liver cancer":"25.6"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005550","CAB016721","CAB016792"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5200000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016721":null,"CAB016792":null,"HPA005550":"AB_1079687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"}},{"Gene":"PROCR","Gene synonym":["CCD41","CD201","EPCR"],"Ensembl":"ENSG00000101000","Gene description":"Protein C receptor","Uniprot":["Q9UNN8"],"Chromosome":"20","Position":"35172072-35216240","Protein class":["Candidate cardiovascular disease genes","CD markers","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"126.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Thymic epithelial cells":"671.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"8.9"},"Antibody":["HPA039461"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"980000000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039461":"AB_10673359"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.62e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"}},{"Gene":"PROKR1","Gene synonym":["GPR73","GPR73a","PKR1","ZAQ"],"Ensembl":"ENSG00000169618","Gene description":"Prokineticin receptor 1","Uniprot":["Q8TCW9"],"Chromosome":"2","Position":"68643579-68658251","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"1.6","epididymis":"3.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"3.5","Neuroblastoma":"1.1"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029396"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029396":"AB_10610285"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"}},{"Gene":"PROKR2","Gene synonym":["dJ680N4.3","GPR73b","GPR73L1","GPRg2","KAL3","PKR2"],"Ensembl":"ENSG00000101292","Gene description":"Prokineticin receptor 2","Uniprot":["Q8NFJ6"],"Chromosome":"20","Position":"5299218-5316954","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism","Kallmann syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"2.0","Cone photoreceptor cells":"1.7","Early spermatids":"1.9","Horizontal cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"17.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047281"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047281":"AB_10960057"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PROM1","Gene synonym":["AC133","CD133","CORD12","MCDR2","PROML1","RP41","STGD4"],"Ensembl":"ENSG00000007062","Gene description":"Prominin 1","Uniprot":["O43490"],"Chromosome":"4","Position":"15963076-16084378","Protein class":["CD markers","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant","Retinitis pigmentosa","Stargardt disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"272.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"305.0","Mucus glandular cells":"171.7","Respiratory ciliated cells":"116.9","Rod photoreceptor cells":"335.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Uterine cancer":"32.4"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Skin - Eccrine sweat gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004922","CAB011525","HPA031053"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011525":"AB_470302","HPA004922":"AB_1846238","HPA031053":"AB_2673713"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"}},{"Gene":"PROM2","Gene synonym":[],"Ensembl":"ENSG00000155066","Gene description":"Prominin 2","Uniprot":["Q8N271"],"Chromosome":"2","Position":"95274449-95291308","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"88.1","skin 1":"60.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"38.5","Club cells":"53.2","Ionocytes":"50.1","Squamous epithelial cells":"40.2","Suprabasal keratinocytes":"50.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"77.9","head and neck cancer":"88.1"},"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB046005","HPA063728"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"CAB046005":"AB_2284371","HPA063728":"AB_2685104"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.16e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"}},{"Gene":"PROS1","Gene synonym":["PROS"],"Ensembl":"ENSG00000184500","Gene description":"Protein S","Uniprot":["P07225"],"Chromosome":"3","Position":"93873051-93980003","Protein class":["Candidate cardiovascular disease genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Blood coagulation","Fibrinolysis","Hemostasis"],"Molecular function":null,"Disease involvement":["Disease variant","FDA approved drug targets","Thrombophilia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"choroid plexus":"107.5","heart muscle":"116.6","liver":"283.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"264.5","Thymic epithelial cells":"87.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"64.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007724","HPA023974","CAB032610"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":22500000000,"Blood concentration - Conc. blood MS [pg\/L]":"5000000000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB032610":"AB_2237647","HPA007724":"AB_1079688","HPA023974":"AB_1855738"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.35e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.42e-5"}},{"Gene":"PRPF38B","Gene synonym":["FLJ10330","NET1"],"Ensembl":"ENSG00000134186","Gene description":"Pre-mRNA processing factor 38B","Uniprot":["Q5VTL8"],"Chromosome":"1","Position":"108692310-108702928","Protein class":["Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053255"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053255":"AB_2682093"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.03e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"}},{"Gene":"PRPH2","Gene synonym":["CACD2","rd2","RDS","RP7","TSPAN22"],"Ensembl":"ENSG00000112619","Gene description":"Peripherin 2","Uniprot":["P23942"],"Chromosome":"6","Position":"42696598-42722597","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Cone-rod dystrophy","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"48","RNA tissue specific nTPM":{"retina":"641.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"274.0","Rod photoreceptor cells":"451.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"2.4","Sarcoma":"1.5"},"RNA tissue cell type enrichment":["Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"hippocampal formation":"2.4"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029458"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029458":"AB_10602193"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"}},{"Gene":"PRPS1","Gene synonym":["CMTX5","DFN2","DFNX1"],"Ensembl":"ENSG00000147224","Gene description":"Phosphoribosyl pyrophosphate synthetase 1","Uniprot":["P60891"],"Chromosome":"X","Position":"107628428-107651993","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Nucleotide biosynthesis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Charcot-Marie-Tooth disease","Deafness","Disease variant","Gout","Intellectual disability","Neurodegeneration","Neuropathy","Non-syndromic deafness","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043760","HPA051269"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA043760":"AB_2678656","HPA051269":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"}},{"Gene":"PRPSAP2","Gene synonym":["PAP41"],"Ensembl":"ENSG00000141127","Gene description":"Phosphoribosyl pyrophosphate synthetase associated protein 2","Uniprot":["O60256"],"Chromosome":"17","Position":"18840085-18931287","Protein class":["Predicted intracellular proteins"],"Biological process":["Nucleotide biosynthesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"274.7"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021881"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"84000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA021881":"AB_1855782"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.71e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"}},{"Gene":"PRR14L","Gene synonym":["C22orf30","MGC50372"],"Ensembl":"ENSG00000183530","Gene description":"Proline rich 14 like","Uniprot":["Q5THK1"],"Chromosome":"22","Position":"31676256-31750140","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062645"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA062645":"AB_2684817"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.00e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-3"}},{"Gene":"PRR23A","Gene synonym":[],"Ensembl":"ENSG00000206260","Gene description":"Proline rich 23A","Uniprot":["A6NEV1"],"Chromosome":"3","Position":"139003962-139006268","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"1.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Spermatocytes":"29.2","Spermatogonia":"9.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"testis cancer":"0.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047473"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Microtubules","Cytokinetic bridge","Mitotic spindle","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoplasm","Microtubules"],"Subcellular additional location":["Nuclear bodies","Cytokinetic bridge","Mitotic spindle","Cytosol"],"Antibody RRID":{"HPA047473":"AB_2680062"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PRR23B","Gene synonym":["FLJ46116"],"Ensembl":"ENSG00000184814","Gene description":"Proline rich 23B","Uniprot":["Q6ZRT6"],"Chromosome":"3","Position":"139019031-139020926","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"testis":"1.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Spermatocytes":"6.8","Spermatogonia":"2.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047473"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nuclear bodies","Microtubules","Cytokinetic bridge","Mitotic spindle","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoplasm","Microtubules"],"Subcellular additional location":["Nuclear bodies","Cytokinetic bridge","Mitotic spindle","Cytosol"],"Antibody RRID":{"HPA047473":"AB_2680062"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PRR5","Gene synonym":["FLJ20185k","PP610","Protor-1"],"Ensembl":"ENSG00000186654","Gene description":"Proline rich 5","Uniprot":["P85299"],"Chromosome":"22","Position":"44668547-44737681","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"65.0","Proximal enterocytes":"48.8","Proximal tubular cells":"49.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"monocytes":"19.1","T-cells":"28.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Fibroblasts","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054072"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054072":"AB_2682369"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.47e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"}},{"Gene":"PRR7","Gene synonym":["MGC10772"],"Ensembl":"ENSG00000131188","Gene description":"Proline rich 7, synaptic","Uniprot":["Q8TB68"],"Chromosome":"5","Position":"177446445-177456286","Protein class":["Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046636"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Nucleoplasm","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046636":"AB_2679730"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.50e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.98e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"}},{"Gene":"PRRC1","Gene synonym":["FLJ32875"],"Ensembl":"ENSG00000164244","Gene description":"Proline rich coiled-coil 1","Uniprot":["Q96M27"],"Chromosome":"5","Position":"127517640-127555085","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039212"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA039212":"AB_10794634"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.35e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"}},{"Gene":"PRRG1","Gene synonym":["PRGP1"],"Ensembl":"ENSG00000130962","Gene description":"Proline rich and Gla domain 1","Uniprot":["O14668"],"Chromosome":"X","Position":"37349309-37457292","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"39.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Oligodendrocytes":"216.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078129"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA078129":"AB_2686878"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.65e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.22e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.05e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"}},{"Gene":"PRRG2","Gene synonym":["PRGP2"],"Ensembl":"ENSG00000126460","Gene description":"Proline rich and Gla domain 2","Uniprot":["O14669"],"Chromosome":"19","Position":"49580646-49591004","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"28.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"43.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010702"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA010702":"AB_1079693"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.82e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"}},{"Gene":"PRRG3","Gene synonym":["TMG3"],"Ensembl":"ENSG00000130032","Gene description":"Proline rich and Gla domain 3","Uniprot":["Q9BZD7"],"Chromosome":"X","Position":"151694607-151705924","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.4","epididymis":"7.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"24","RNA single cell type specific nTPM":{"Cardiomyocytes":"554.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"testis cancer":"2.6","thyroid cancer":"1.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060566"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060566":"AB_2684321"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"}},{"Gene":"PRRG4","Gene synonym":["TMG4"],"Ensembl":"ENSG00000135378","Gene description":"Proline rich and Gla domain 4","Uniprot":["Q9BZD6"],"Chromosome":"11","Position":"32829927-32858120","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"122.4","Basal squamous epithelial cells":"127.9","Squamous epithelial cells":"148.1","Suprabasal keratinocytes":"189.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"11.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"11.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Liver - Hepatocytes","Lung - Alveolar cells type 1","Prostate - Prostate basal glandular cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009040","HPA024566"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA009040":"AB_1079694","HPA024566":"AB_2237712"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"}},{"Gene":"PRRT1","Gene synonym":["C6orf31","DSPD1","IFITMD7","NG5"],"Ensembl":"ENSG00000204314","Gene description":"Proline rich transmembrane protein 1","Uniprot":["Q99946"],"Chromosome":"6","Position":"32148359-32153083","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"40.1","ovary":"11.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Bipolar cells":"46.1","Granulosa cells":"180.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"amygdala":"38.4","cerebral cortex":"40.1","hippocampal formation":"37.0","white matter":"17.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055149","HPA059099"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055149":"AB_2682717","HPA059099":"AB_2732632"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"}},{"Gene":"PRRT1B","Gene synonym":["DSPD2","IFITMD8"],"Ensembl":"ENSG00000283526","Gene description":"Proline rich transmembrane protein 1B","Uniprot":["A0A1B0GWB2"],"Chromosome":"9","Position":"131545514-131558620","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"6.4","lung":"4.1","pancreas":"4.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"3.9","liver cancer":"3.5","prostate cancer":"8.6"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Alveolar cells type 1","Prostate - Prostate glandular cells","Stomach - Chief cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PRRT2","Gene synonym":["DKFZp547J199","DSPB3","DYT10","EKD1","FICCA","FLJ25513","ICCA","IFITMD1","PKC"],"Ensembl":"ENSG00000167371","Gene description":"Proline rich transmembrane protein 2","Uniprot":["Q7Z6L0"],"Chromosome":"16","Position":"29811382-29815892","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Dystonia","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"124.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"74.8","Horizontal cells":"65.4","Leydig cells":"37.2","Peritubular cells":"42.2","Rod photoreceptor cells":"43.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"NK-cell":"3.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"NK-cells":"3.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"39.9"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014447","HPA019203","HPA048045"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014447":"AB_1855786","HPA019203":"AB_2670097","HPA048045":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"}},{"Gene":"PRRT3","Gene synonym":["FLJ33674"],"Ensembl":"ENSG00000163704","Gene description":"Proline rich transmembrane protein 3","Uniprot":["Q5FWE3"],"Chromosome":"3","Position":"9945542-9952408","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"11.6","fallopian tube":"7.6","parathyroid gland":"15.3","pituitary gland":"11.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"23.1","Rod photoreceptor cells":"25.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035127","HPA035128","HPA069859"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"83000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA035127":"AB_10602822","HPA035128":"AB_2674482","HPA069859":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"}},{"Gene":"PRRT4","Gene synonym":[],"Ensembl":"ENSG00000224940","Gene description":"Proline rich transmembrane protein 4","Uniprot":["C9JH25"],"Chromosome":"7","Position":"128350325-128361685","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adipose tissue":"16.3","bone marrow":"57.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Horizontal cells":"19.9","Inhibitory neurons":"12.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"29.4","Neuroblastoma":"62.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Lung - Neutrophil_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046373","HPA052681"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Peroxisomes","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Peroxisomes","Plasma membrane"],"Antibody RRID":{"HPA046373":"AB_2679642","HPA052681":"AB_2681912"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"}},{"Gene":"PRSS45P","Gene synonym":["PRSS45","TESPL","TESSP5"],"Ensembl":"ENSG00000188086","Gene description":"Serine protease 45, pseudogene","Uniprot":["Q7RTY3"],"Chromosome":"3","Position":"46742092-46750891","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"6.4","skeletal muscle":"10.4"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060284"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060284":"AB_2684242"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-3"}},{"Gene":"PRSS48","Gene synonym":["ESSPL"],"Ensembl":"ENSG00000189099","Gene description":"Serine protease 48","Uniprot":["Q7RTY5"],"Chromosome":"4","Position":"151277171-151291453","Protein class":["Enzymes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"choroid plexus":"18.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"2.1","Oligodendrocyte precursor cells":"8.2","Oligodendrocytes":"3.5","Spermatocytes":"4.1","Spermatogonia":"2.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053801"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053801":"AB_2682267"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PRSS8","Gene synonym":[],"Ensembl":"ENSG00000052344","Gene description":"Serine protease 8","Uniprot":["Q16651"],"Chromosome":"16","Position":"31131433-31135727","Protein class":["Enzymes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"245.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"268.2","Extravillous trophoblasts":"775.7","Proximal enterocytes":"336.5","Syncytiotrophoblasts":"640.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"2.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Skin - Keratinocyte (granular)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"8","RNA mouse brain regional specific nTPM":{"hippocampal formation":"1.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030436"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030436":"AB_10602291"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.05e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-3"}},{"Gene":"PRTG","Gene synonym":["FLJ25756","IGDCC5"],"Ensembl":"ENSG00000166450","Gene description":"Protogenin","Uniprot":["Q2VWP7"],"Chromosome":"15","Position":"55611544-55743152","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"10.4","thyroid gland":"10.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"29.4","Cone photoreceptor cells":"93.1","Oligodendrocyte precursor cells":"49.6","Rod photoreceptor cells":"77.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"testis cancer":"172.9"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Lung - Alveolar cells type 2","Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032138"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"HPA032138":"AB_10669675"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-6"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"}},{"Gene":"PRUNE1","Gene synonym":["DRES-17","H-PRUNE","HTCD37","PRUNE"],"Ensembl":"ENSG00000143363","Gene description":"Prune exopolyphosphatase 1","Uniprot":["Q86TP1"],"Chromosome":"1","Position":"151008420-151035713","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Intellectual disability","Neurodegeneration","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"36.8","Early spermatids":"48.5","Late spermatids":"70.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028411"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"41000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028411":"AB_10603229"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.86e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.48e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"PRXL2A","Gene synonym":["Adrx","C10orf58","FAM213A","MGC4248","PAMM"],"Ensembl":"ENSG00000122378","Gene description":"Peroxiredoxin like 2A","Uniprot":["Q9BRX8"],"Chromosome":"10","Position":"80407829-80437115","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Antioxidant"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"405.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"394.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"plasmacytoid DC":"166.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"166.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009025","HPA024565"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA009025":"AB_1078312","HPA024565":"AB_1845519"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.11e-4"}},{"Gene":"PRXL2B","Gene synonym":["C1orf93","FAM213B","MGC26818"],"Ensembl":"ENSG00000157870","Gene description":"Peroxiredoxin like 2B","Uniprot":["Q8TBF2"],"Chromosome":"1","Position":"2586491-2591469","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Prostaglandin biosynthesis","Prostaglandin metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Paneth cells":"47.4","Proximal enterocytes":"73.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006403"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA006403":"AB_1853870"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.28e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"}},{"Gene":"PSCA","Gene synonym":[],"Ensembl":"ENSG00000167653","Gene description":"Prostate stem cell antigen","Uniprot":["O43653"],"Chromosome":"8","Position":"142670308-142682725","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"stomach 1":"3019.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"2012.0","Gastric mucus-secreting cells":"4695.7","Ionocytes":"577.7","Respiratory ciliated cells":"939.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"urothelial cancer":"785.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"132.8","pancreatic cancer":"199.0"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"spinal cord":"38.2"},"Antibody":["HPA030783","HPA056418"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA030783":"AB_2673611","HPA056418":"AB_2683123"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.60e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"}},{"Gene":"PSEN1","Gene synonym":["AD3","FAD","PS1","S182"],"Ensembl":"ENSG00000080815","Gene description":"Presenilin 1","Uniprot":["P49768"],"Chromosome":"14","Position":"73136418-73223691","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Cell adhesion","Notch signaling pathway"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Alzheimer disease","Amyloidosis","Cancer-related genes","Cardiomyopathy","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"373.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006844","HPA030760","HPA067496"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cell Junctions"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cell Junctions"],"Antibody RRID":{"CAB006844":null,"HPA030760":"AB_10696211","HPA067496":"AB_2685853"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.52e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"}},{"Gene":"PSEN2","Gene synonym":["AD3L","AD4","PS2","STM2"],"Ensembl":"ENSG00000143801","Gene description":"Presenilin 2","Uniprot":["P49810"],"Chromosome":"1","Position":"226870184-226927726","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Notch signaling pathway"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Alzheimer disease","Amyloidosis","Cardiomyopathy","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"6.0","Melanocytes":"10.4","Microglial cells":"5.5","Plasma cells":"7.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"PSENEN","Gene synonym":["PEN2"],"Ensembl":"ENSG00000205155","Gene description":"Presenilin enhancer, gamma-secretase subunit","Uniprot":["Q9NZ42"],"Chromosome":"19","Position":"35745600-35747519","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Notch signaling pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"552.2","Respiratory ciliated cells":"634.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047435"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047435":"AB_2680047"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"}},{"Gene":"PSG9","Gene synonym":["PSG11","PSGII"],"Ensembl":"ENSG00000183668","Gene description":"Pregnancy specific beta-1-glycoprotein 9","Uniprot":["Q00887"],"Chromosome":"19","Position":"43211791-43269530","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"135","RNA tissue specific nTPM":{"placenta":"106.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"25","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"222.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"27.5","Rhabdoid":"25.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046327"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in female reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"43000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046327":"AB_2679624"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PSKH1","Gene synonym":[],"Ensembl":"ENSG00000159792","Gene description":"Protein serine kinase H1","Uniprot":["P11801"],"Chromosome":"16","Position":"67893254-67929676","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053927","HPA062763"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nuclear speckles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA053927":"AB_2682312","HPA062763":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.28e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"}},{"Gene":"PSKH2","Gene synonym":[],"Ensembl":"ENSG00000147613","Gene description":"Protein serine kinase H2","Uniprot":["Q96QS6"],"Chromosome":"8","Position":"86047109-86088621","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"retina":"2.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"34.5","Rod photoreceptor cells":"8.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"testis cancer":"0.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015095","HPA056839"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA015095":"AB_1855815","HPA056839":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PSMA6","Gene synonym":["IOTA","MGC22756","MGC2333","MGC23846","p27K","PROS27"],"Ensembl":"ENSG00000100902","Gene description":"Proteasome 20S subunit alpha 6","Uniprot":["P60900"],"Chromosome":"14","Position":"35278633-35317493","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"338.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003049"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA003049":"AB_1079703"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.27e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"}},{"Gene":"PSMD1","Gene synonym":["P112","Rpn2","S1"],"Ensembl":"ENSG00000173692","Gene description":"Proteasome 26S subunit, non-ATPase 1","Uniprot":["Q99460"],"Chromosome":"2","Position":"231056845-231173116","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"279.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB021092","HPA036736","HPA036737"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"230000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB021092":"AB_10123242","HPA036736":"AB_2675278","HPA036737":"AB_2675279"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.63e-12"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.34e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-3"}},{"Gene":"PSMD11","Gene synonym":["MGC3844","p44.5","Rpn6","S9"],"Ensembl":"ENSG00000108671","Gene description":"Proteasome 26S subunit, non-ATPase 11","Uniprot":["O00231"],"Chromosome":"17","Position":"32444379-32483319","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"347.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042275","HPA067433"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"95000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA042275":"AB_10794793","HPA067433":"AB_2685838"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.33e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.73e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"}},{"Gene":"PSMD6","Gene synonym":["KIAA0107","p44S10","Rpn7","S10"],"Ensembl":"ENSG00000163636","Gene description":"Proteasome 26S subunit, non-ATPase 6","Uniprot":["Q15008"],"Chromosome":"3","Position":"64010550-64024010","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"285.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"544.7","Late spermatids":"742.9","Spermatocytes":"322.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036921","HPA036922"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036921":"AB_2675383","HPA036922":"AB_10670850"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.68e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-3"}},{"Gene":"PSME3","Gene synonym":["Ki","PA28-gamma","PA28G","REG-GAMMA"],"Ensembl":"ENSG00000131467","Gene description":"Proteasome activator subunit 3","Uniprot":["P61289"],"Chromosome":"17","Position":"42824385-42843760","Protein class":["Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle","Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"154.1","Late spermatids":"208.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008388","HPA012510"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"460000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB008388":"AB_592552","HPA012510":"AB_1855752"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.41e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"PSME4","Gene synonym":["KIAA0077","PA200"],"Ensembl":"ENSG00000068878","Gene description":"Proteasome activator subunit 4","Uniprot":["Q14997"],"Chromosome":"2","Position":"53864069-53970993","Protein class":["Predicted intracellular proteins"],"Biological process":["Differentiation","DNA damage","DNA repair","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"59.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"225.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060922"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA060922":"AB_2684386"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.99e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.84e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"}},{"Gene":"PSMG4","Gene synonym":["C6orf86","PAC4"],"Ensembl":"ENSG00000180822","Gene description":"Proteasome assembly chaperone 4","Uniprot":["Q5JS54"],"Chromosome":"6","Position":"3231403-3303373","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067652","HPA074376","HPA075846"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA067652":"AB_2685880","HPA074376":null,"HPA075846":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"}},{"Gene":"PTAFR","Gene synonym":[],"Ensembl":"ENSG00000169403","Gene description":"Platelet activating factor receptor","Uniprot":["P25105"],"Chromosome":"1","Position":"28147166-28193936","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Chemotaxis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"41.1","lymphoid tissue":"30.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"36.9","Hofbauer cells":"77.0","Ionocytes":"32.5","Kupffer cells":"75.1","Langerhans cells":"87.1","Macrophages":"69.5","monocytes":"32.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"256.7","eosinophil":"906.5","neutrophil":"747.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"906.5","monocytes":"256.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"21.8","head and neck cancer":"19.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027543"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA027543":"AB_10610287"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"}},{"Gene":"PTCH1","Gene synonym":["BCNS","NBCCS","PTCH"],"Ensembl":"ENSG00000185920","Gene description":"Patched 1","Uniprot":["Q13635"],"Chromosome":"9","Position":"95442980-95517057","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Holoprosencephaly","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"26.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"260.1","Leydig cells":"186.5","Peritubular cells":"426.5","Theca cells":"103.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"6.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"6.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Peritubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013717","HPA075072"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB013717":null,"HPA075072":"AB_2686733"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"}},{"Gene":"PTCH2","Gene synonym":[],"Ensembl":"ENSG00000117425","Gene description":"Patched 2","Uniprot":["Q9Y6C5"],"Chromosome":"1","Position":"44819844-44843253","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"ovary":"24.6","parathyroid gland":"59.1","salivary gland":"75.2","testis":"25.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"112.5","Peritubular cells":"69.8","Theca cells":"124.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"9.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Peritubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046839"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 1: Non-specific - Nucleosome assembly","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA046839":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.74e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"}},{"Gene":"PTCHD1","Gene synonym":["FLJ30296"],"Ensembl":"ENSG00000165186","Gene description":"Patched domain containing 1","Uniprot":["Q96NR3"],"Chromosome":"X","Position":"23334849-23404374","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Autism","Autism spectrum disorder"],"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"15.2","intestine":"6.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"33.5","Breast glandular cells":"9.8","Excitatory neurons":"21.7","Horizontal cells":"16.7","Mucus glandular cells":"7.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"1.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Heart muscle - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046110"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046110":"AB_2679541"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"}},{"Gene":"PTCHD4","Gene synonym":["C6orf138","dJ402H5.2","FLJ41841","PTCH53"],"Ensembl":"ENSG00000244694","Gene description":"Patched domain containing 4","Uniprot":["Q6ZW05"],"Chromosome":"6","Position":"47856673-48111197","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Inhibitory neurons":"467.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"melanoma":"1.1","renal cancer":"1.6","thyroid cancer":"4.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"testis cancer":"20.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041276"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041276":"AB_10796570"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.49e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-3"}},{"Gene":"PTCRA","Gene synonym":["PT-ALPHA","PTA"],"Ensembl":"ENSG00000171611","Gene description":"Pre T cell antigen receptor alpha","Uniprot":["Q6ISU1"],"Chromosome":"6","Position":"42915989-42925838","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"38","RNA tissue specific nTPM":{"lymphoid tissue":"128.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"dendritic cells":"268.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"46","RNA blood cell specific nTPM":{"plasmacytoid DC":"410.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"46","RNA blood lineage specific nTPM":{"dendritic cells":"410.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"17","RNA cell line specific nTPM":{"Leukemia":"9.5","skin cancer":"3.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"}},{"Gene":"PTDSS1","Gene synonym":["KIAA0024","PSS1","PSSA"],"Ensembl":"ENSG00000156471","Gene description":"Phosphatidylserine synthase 1","Uniprot":["P48651"],"Chromosome":"8","Position":"96261902-96336995","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Dwarfism","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"102.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"10.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016852"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA016852":"AB_1855878"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.83e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"}},{"Gene":"PTDSS2","Gene synonym":["PSS2"],"Ensembl":"ENSG00000174915","Gene description":"Phosphatidylserine synthase 2","Uniprot":["Q9BVG9"],"Chromosome":"11","Position":"448268-491399","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"139.7","Late spermatids":"340.7","Spermatocytes":"87.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038928","HPA038929"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038928":"AB_10672832","HPA038929":"AB_2676274"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.12e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"PTGDR","Gene synonym":["DP","DP1","PTGDR1"],"Ensembl":"ENSG00000168229","Gene description":"Prostaglandin D2 receptor","Uniprot":["Q13258"],"Chromosome":"14","Position":"52267698-52276724","Protein class":["Disease related genes","G-protein coupled receptors","Potential drug targets","Predicted membrane proteins"],"Biological process":["Mast cell degranulation"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Asthma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"7.9","lymphoid tissue":"6.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"16.4","NK-cells":"118.8","T-cells":"29.8","Undifferentiated cells":"27.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"68.0","NK-cell":"90.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"NK-cells":"90.3","T-cells":"68.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.8"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Kidney - T-cells","Liver - NK-cells (Liver)","Lung - NK-cells (Lung)","Stomach - Fibroblasts","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049668"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049668":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"}},{"Gene":"PTGDR2","Gene synonym":["CD294","CRTH2","DP2","GPR44"],"Ensembl":"ENSG00000183134","Gene description":"Prostaglandin D2 receptor 2","Uniprot":["Q9Y5Y4"],"Chromosome":"11","Position":"60850933-60855950","Protein class":["CD markers","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.2","intestine":"8.2","stomach 1":"9.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"2.7","granulocytes":"3.0","Intestinal goblet cells":"2.0","Langerhans cells":"2.7","Microglial cells":"1.8","monocytes":"7.3","Muller glia cells":"2.4","Smooth muscle cells":"3.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"178.1","eosinophil":"234.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"234.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"3.2"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014259"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014259":"AB_1849304"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"}},{"Gene":"PTGDS","Gene synonym":["L-PGDS","PGDS"],"Ensembl":"ENSG00000107317","Gene description":"Prostaglandin D2 synthase","Uniprot":["P41222"],"Chromosome":"9","Position":"136975092-136981742","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Mast cell degranulation","Prostaglandin biosynthesis","Prostaglandin metabolism","Transport"],"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"4898.3","testis":"3242.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Leydig cells":"31099.3","Peritubular cells":"49871.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"27","RNA blood cell specific nTPM":{"plasmacytoid DC":"1386.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"27","RNA blood lineage specific nTPM":{"dendritic cells":"1386.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"79.7","ovarian cancer":"30.2"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Podocytes","Liver - Hepatic stellate cells","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004938","CAB009916","HPA067456"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2500000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009916":"AB_2174617","HPA004938":"AB_1855745","HPA067456":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.19e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"}},{"Gene":"PTGER1","Gene synonym":["EP1"],"Ensembl":"ENSG00000160951","Gene description":"Prostaglandin E receptor 1","Uniprot":["P34995"],"Chromosome":"19","Position":"14472466-14475354","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"kidney":"30.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Collecting duct cells":"84.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"4.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"1.4"},"RNA tissue cell type enrichment":["Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"}},{"Gene":"PTGER2","Gene synonym":["EP2"],"Ensembl":"ENSG00000125384","Gene description":"Prostaglandin E receptor 2","Uniprot":["P43116"],"Chromosome":"14","Position":"52314305-52328598","Protein class":["FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"38.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"30.8","Kupffer cells":"31.1","Macrophages":"30.5","monocytes":"65.8","NK-cells":"112.5","T-cells":"62.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"}},{"Gene":"PTGER3","Gene synonym":["EP3","lnc003875"],"Ensembl":"ENSG00000050628","Gene description":"Prostaglandin E receptor 3","Uniprot":["P43115"],"Chromosome":"1","Position":"70852353-71047808","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"95.2","kidney":"81.2","smooth muscle":"68.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Distal tubular cells":"158.6","Langerhans cells":"94.2","Thymic epithelial cells":"51.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"breast cancer":"4.1","renal cancer":"9.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"59","RNA blood cell specific nTPM":{"basophil":"43.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"59","RNA blood lineage specific nTPM":{"granulocytes":"43.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Bone cancer":"51.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010689"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010689":"AB_1855883"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-4"}},{"Gene":"PTGER4","Gene synonym":["EP4"],"Ensembl":"ENSG00000171522","Gene description":"Prostaglandin E receptor 4","Uniprot":["P35408"],"Chromosome":"5","Position":"40679915-40693735","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"85.7","pancreas":"54.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"146.1","monocytes":"217.3","NK-cells":"168.7","T-cells":"233.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011226","HPA012756"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011226":"AB_1855885","HPA012756":"AB_1855884"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.48e-4"}},{"Gene":"PTGES","Gene synonym":["MGST-IV","MGST1-L1","MGST1L1","PIG12","TP53I12"],"Ensembl":"ENSG00000148344","Gene description":"Prostaglandin E synthase","Uniprot":["O14684"],"Chromosome":"9","Position":"129738331-129753042","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Prostaglandin biosynthesis","Prostaglandin metabolism"],"Molecular function":["Isomerase","Oxidoreductase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"seminal vesicle":"84.2","urinary bladder":"78.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"91.7","Basal respiratory cells":"110.9","Cytotrophoblasts":"157.0","Extravillous trophoblasts":"335.6","Ionocytes":"93.9","Syncytiotrophoblasts":"304.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"69.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"28.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"28.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Skeletal muscle - Fibroblasts","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045064"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA045064":"AB_10795889"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.32e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.97e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"}},{"Gene":"PTGES2","Gene synonym":["C9orf15","FLJ14038"],"Ensembl":"ENSG00000148334","Gene description":"Prostaglandin E synthase 2","Uniprot":["Q9H7Z7"],"Chromosome":"9","Position":"128120693-128128462","Protein class":["Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Prostaglandin biosynthesis","Prostaglandin metabolism"],"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020733"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA020733":"AB_2670508"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.83e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"PTGFR","Gene synonym":["FP"],"Ensembl":"ENSG00000122420","Gene description":"Prostaglandin F receptor","Uniprot":["P43088"],"Chromosome":"1","Position":"78303884-78540701","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"20.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"22.3","Collecting duct cells":"11.8","Fibroblasts":"27.2","Inhibitory neurons":"10.1","Late spermatids":"11.1","Microglial cells":"17.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"6.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Heart muscle - Fibroblasts","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"}},{"Gene":"PTGFRN","Gene synonym":["CD315","CD9P-1","EWI-F","FLJ11001","FPRP","KIAA1436","SMAP-6"],"Ensembl":"ENSG00000134247","Gene description":"Prostaglandin F2 receptor inhibitor","Uniprot":["Q9P2B2"],"Chromosome":"1","Position":"116909916-116990353","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"58.2","Cardiomyocytes":"70.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Breast - Breast myoepithelial cells","Colon - Smooth muscle cells","Lung - Fibroblast_2","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017074"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"340000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017074":"AB_1855888"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.98e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"}},{"Gene":"PTGIR","Gene synonym":["IP"],"Ensembl":"ENSG00000160013","Gene description":"Prostaglandin I2 receptor","Uniprot":["P43119"],"Chromosome":"19","Position":"46620468-46625089","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"55.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Langerhans cells":"242.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"classical monocyte":"28.2","intermediate monocyte":"65.3","myeloid DC":"20.9","non-classical monocyte":"38.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"20.9","monocytes":"65.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"6.3","Neuroblastoma":"7.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.09e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.74e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"}},{"Gene":"PTH1R","Gene synonym":["PTHR","PTHR1"],"Ensembl":"ENSG00000160801","Gene description":"Parathyroid hormone 1 receptor","Uniprot":["Q03431"],"Chromosome":"3","Position":"46877721-46903799","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Dwarfism","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"kidney":"586.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"33.5","Distal tubular cells":"49.8","Extravillous trophoblasts":"73.2","Proximal tubular cells":"216.7","Sertoli cells":"58.0","Smooth muscle cells":"33.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"renal cancer":"18.8","testis cancer":"5.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"5.6","testis cancer":"5.2"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075879"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA075879":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.79e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-3"}},{"Gene":"PTH2R","Gene synonym":["PTHR2"],"Ensembl":"ENSG00000144407","Gene description":"Parathyroid hormone 2 receptor","Uniprot":["P49190"],"Chromosome":"2","Position":"208359714-208854503","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"16.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"12.1","Excitatory neurons":"15.7","Proximal tubular cells":"14.8","Rod photoreceptor cells":"24.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"6.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010655"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010655":"AB_2668333"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"}},{"Gene":"PTK7","Gene synonym":["CCK4"],"Ensembl":"ENSG00000112655","Gene description":"Protein tyrosine kinase 7 (inactive)","Uniprot":["Q13308"],"Chromosome":"6","Position":"43076307-43161719","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Wnt signaling pathway"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"139.4","Endometrial stromal cells":"77.6","Late spermatids":"191.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"plasmacytoid DC":"13.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"13.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Heart muscle - Fibroblasts","Skeletal muscle - Fibroblasts","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003222"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003222":"AB_1079713"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-3"}},{"Gene":"PTPMT1","Gene synonym":["DUSP23","MOSP","PLIP"],"Ensembl":"ENSG00000110536","Gene description":"Protein tyrosine phosphatase mitochondrial 1","Uniprot":["Q8WUK0"],"Chromosome":"11","Position":"47565430-47573461","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"197.5","Late spermatids":"579.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043932","HPA060060"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA043932":"AB_2678738","HPA060060":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.04e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"}},{"Gene":"PTPN1","Gene synonym":["PTP1B"],"Ensembl":"ENSG00000196396","Gene description":"Protein tyrosine phosphatase non-receptor type 1","Uniprot":["P18031"],"Chromosome":"20","Position":"50510321-50585241","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"229.8","dendritic cells":"331.7","Langerhans cells":"207.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009329","HPA012542","CAB015217"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB009329":"AB_2174944","CAB015217":null,"HPA012542":"AB_1855915"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"}},{"Gene":"PTPN2","Gene synonym":["PTPT","TC-PTP","TCELLPTP","TCPTP"],"Ensembl":"ENSG00000175354","Gene description":"Protein tyrosine phosphatase non-receptor type 2","Uniprot":["P17706"],"Chromosome":"18","Position":"12785478-12929643","Protein class":["Enzymes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"99.8"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015004","HPA046176"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA015004":"AB_2669131","HPA046176":"AB_2679569"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.37e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"}},{"Gene":"PTPN5","Gene synonym":["PTPSTEP","STEP","STEP61"],"Ensembl":"ENSG00000110786","Gene description":"Protein tyrosine phosphatase non-receptor type 5","Uniprot":["P54829"],"Chromosome":"11","Position":"18727928-18792721","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"161.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"58.2","Inhibitory neurons":"50.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"1.6","testis cancer":"2.0"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"161.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"2.8","Rhabdoid":"9.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031014","HPA072091"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA031014":"AB_10669550","HPA072091":"AB_2686487"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"}},{"Gene":"PTPRA","Gene synonym":["HLPR","HPTPA","LRP","PTPA","PTPRL2","RPTPA"],"Ensembl":"ENSG00000132670","Gene description":"Protein tyrosine phosphatase receptor type A","Uniprot":["P18433"],"Chromosome":"20","Position":"2864184-3039076","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029412","CAB034366","HPA069480"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB034366":"AB_2269058","HPA029412":"AB_10602293","HPA069480":"AB_2686141"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.29e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"}},{"Gene":"PTPRB","Gene synonym":["PTPB"],"Ensembl":"ENSG00000127329","Gene description":"Protein tyrosine phosphatase receptor type B","Uniprot":["P23467"],"Chromosome":"12","Position":"70515870-70637440","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"208.8","Endothelial cells":"225.2","Inhibitory neurons":"67.1","Microglial cells":"160.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"11.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Kidney - Endothelial cells","Liver - Sinusoid Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004782","HPA067868"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cell Junctions"],"Antibody RRID":{"CAB004782":null,"HPA067868":"AB_2685911"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.05e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"}},{"Gene":"PTPRC","Gene synonym":["CD45","GP180","LCA","T200"],"Ensembl":"ENSG00000081237","Gene description":"Protein tyrosine phosphatase receptor type C","Uniprot":["P08575"],"Chromosome":"1","Position":"198638457-198757476","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Cancer-related genes","Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"208.6","lymphoid tissue":"329.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"506.7","Kupffer cells":"464.5","Macrophages":"507.9","monocytes":"1400.2","NK-cells":"1356.4","T-cells":"1034.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"117.5","lymphoma":"158.9"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Breast - T-cells","Kidney - T-cells","Lung - NK-cells (Lung)","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000052","HPA000440","CAB002800","CAB056154","CAB068221"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB000052":"AB_2314143","CAB002800":"AB_2237910","CAB056154":"AB_2665572","CAB068221":"AB_2665571","HPA000440":"AB_611377"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"}},{"Gene":"PTPRCAP","Gene synonym":["CD45-AP","LPAP"],"Ensembl":"ENSG00000213402","Gene description":"Protein tyrosine phosphatase receptor type C associated protein","Uniprot":["Q14761"],"Chromosome":"11","Position":"67435510-67437682","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"79.7","lymphoid tissue":"174.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"B-cells":"175.7","Plasma cells":"204.1","T-cells":"140.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"137","RNA cell line specific nTPM":{"Leukemia":"232.9","lymphoma":"312.4","Myeloma":"84.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"1.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043734"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA043734":"AB_10962214"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"PTPRD","Gene synonym":["HPTP","PTPD"],"Ensembl":"ENSG00000153707","Gene description":"Protein tyrosine phosphatase receptor type D","Uniprot":["P23468"],"Chromosome":"9","Position":"8314246-10612723","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"70.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"4511.3","Inhibitory neurons":"1126.6","Oligodendrocyte precursor cells":"1120.6","Oligodendrocytes":"2974.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"21.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Breast - Fibroblasts","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054829"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA054829":"AB_2682618"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.45e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"}},{"Gene":"PTPRE","Gene synonym":["PTPE"],"Ensembl":"ENSG00000132334","Gene description":"Protein tyrosine phosphatase receptor type E","Uniprot":["P23469"],"Chromosome":"10","Position":"127907103-128085855","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"46.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"496.4","Langerhans cells":"396.4","Macrophages":"254.0","monocytes":"474.4","Oligodendrocyte precursor cells":"236.8","Schwann cells":"254.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"634.6","plasmacytoid DC":"475.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"475.9","granulocytes":"634.6","monocytes":"175.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015870","HPA021872"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA015870":"AB_1855759","HPA021872":"AB_1855760"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.08e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"}},{"Gene":"PTPRF","Gene synonym":["LAR"],"Ensembl":"ENSG00000142949","Gene description":"Protein tyrosine phosphatase receptor type F","Uniprot":["P10586"],"Chromosome":"1","Position":"43525187-43623666","Protein class":["Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Heparin-binding","Hydrolase","Protein phosphatase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"337.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Liver - Hepatocytes","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012710"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA012710":"AB_1855933"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.03e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"}},{"Gene":"PTPRG","Gene synonym":["PTPG","RPTPG"],"Ensembl":"ENSG00000144724","Gene description":"Protein tyrosine phosphatase receptor type G","Uniprot":["P23470"],"Chromosome":"3","Position":"61561569-62297609","Protein class":["Enzymes","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"345.7","Excitatory neurons":"410.0","Inhibitory neurons":"668.3","Microglial cells":"750.7","Oligodendrocyte precursor cells":"881.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000546","HPA064237"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"520000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA000546":null,"HPA064237":"AB_2685221"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.10e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"}},{"Gene":"PTPRH","Gene synonym":["SAP-1"],"Ensembl":"ENSG00000080031","Gene description":"Protein tyrosine phosphatase receptor type H","Uniprot":["Q9HD43"],"Chromosome":"19","Position":"55181247-55209506","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"24.2","intestine":"68.6","stomach 1":"23.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"62.6","Gastric mucus-secreting cells":"57.2","Intestinal goblet cells":"29.1","Paneth cells":"35.8","Proximal enterocytes":"107.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"16.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Urothelial cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042300"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA042300":"AB_10796900"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"}},{"Gene":"PTPRJ","Gene synonym":["CD148","DEP1","HPTPeta"],"Ensembl":"ENSG00000149177","Gene description":"Protein tyrosine phosphatase receptor type J","Uniprot":["Q12913"],"Chromosome":"11","Position":"47980558-48170841","Protein class":["CD markers","Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"163.5","Microglial cells":"184.3","Oligodendrocyte precursor cells":"229.6","Oligodendrocytes":"158.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"9.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"9.5","monocytes":"4.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Lung - Neutrophil_2","Prostate - Prostate glandular cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006026"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"670000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA006026":"AB_1078446"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.13e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"}},{"Gene":"PTPRK","Gene synonym":["R-PTP-kappa"],"Ensembl":"ENSG00000152894","Gene description":"Protein tyrosine phosphatase receptor type K","Uniprot":["Q15262"],"Chromosome":"6","Position":"127968785-128520616","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"879.3","Oligodendrocyte precursor cells":"299.9","Oligodendrocytes":"1206.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"memory B-cell":"1.6","naive B-cell":"2.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"2.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054056","HPA054822"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"HPA054056":"AB_2682359","HPA054822":"AB_2682614"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.33e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"}},{"Gene":"PTPRM","Gene synonym":["hR-PTPu","PTPRL1","RPTPU"],"Ensembl":"ENSG00000173482","Gene description":"Protein tyrosine phosphatase receptor type M","Uniprot":["P28827"],"Chromosome":"18","Position":"7566782-8406861","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Hydrolase","Protein phosphatase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"134.2","Astrocytes":"182.2","Inhibitory neurons":"734.4","Microglial cells":"256.3","Oligodendrocyte precursor cells":"215.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory CD8 T-cell":"4.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"dendritic cells":"1.8","T-cells":"4.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003891","CAB022442","CAB022443"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB022442":null,"CAB022443":null,"HPA003891":"AB_2667073"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.65e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.07e-4"}},{"Gene":"PTPRN","Gene synonym":["IA-2","ICA512"],"Ensembl":"ENSG00000054356","Gene description":"Protein tyrosine phosphatase receptor type N","Uniprot":["Q16849"],"Chromosome":"2","Position":"219289623-219309648","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Receptor"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"234.3","pituitary gland":"182.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"55.8","Cone photoreceptor cells":"65.5","Excitatory neurons":"44.0","Horizontal cells":"103.8","Inhibitory neurons":"47.0","Pancreatic endocrine cells":"82.4","Rod photoreceptor cells":"29.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"glioma":"5.3","pancreatic cancer":"18.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"40.3","thyroid cancer":"37.3"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007152","HPA007179"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA007152":"AB_2667759","HPA007179":"AB_1079714"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.45e-7"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"}},{"Gene":"PTPRN2","Gene synonym":["IA-2beta","ICAAR","KIAA0387","phogrin"],"Ensembl":"ENSG00000155093","Gene description":"Protein tyrosine phosphatase receptor type N2","Uniprot":["Q92932"],"Chromosome":"7","Position":"157539056-158587823","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid metabolism","Phospholipid metabolism"],"Molecular function":["Hydrolase","Protein phosphatase","Receptor"],"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"49.9","pancreas":"98.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"433.1","Inhibitory neurons":"423.5","Oligodendrocyte precursor cells":"132.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"40.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"23.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"23.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"32.8"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Heart muscle - Fibroblasts","Pancreas - Exocrine glandular cells","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006900","HPA007255","HPA026656"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA006900":"AB_1079715","HPA007255":null,"HPA026656":"AB_1855912"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.37e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.68e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"}},{"Gene":"PTPRO","Gene synonym":["GLEPP1","NPHS6","PTP-oc","PTP-U2","PTPU2"],"Ensembl":"ENSG00000151490","Gene description":"Protein tyrosine phosphatase receptor type O","Uniprot":["Q16827"],"Chromosome":"12","Position":"15322257-15602175","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"26.8","kidney":"36.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"190.8","Horizontal cells":"54.5","Inhibitory neurons":"224.7","Oligodendrocyte precursor cells":"121.3","Undifferentiated cells":"47.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"8.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"9.3","Gastric cancer":"6.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Heart muscle - Macrophages","Kidney - Podocytes","Liver - Kupffer cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"175.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034525"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034525":"AB_10669785"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"PTPRQ","Gene synonym":["DFNB84"],"Ensembl":"ENSG00000139304","Gene description":"Protein tyrosine phosphatase receptor type Q","Uniprot":[],"Chromosome":"12","Position":"80402178-80680273","Protein class":["Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"7.1","urinary bladder":"4.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"13.3","Excitatory neurons":"11.0","Late spermatids":"4.3","Thymic epithelial cells":"21.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"4.1","Gallbladder cancer":"6.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Podocytes","Lung - Alveolar cells type 1","Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053245"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA053245":"AB_2682087"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"}},{"Gene":"PTPRR","Gene synonym":["EC-PTP","PCPTP1","PTP-SL","PTPBR7","PTPRQ"],"Ensembl":"ENSG00000153233","Gene description":"Protein tyrosine phosphatase receptor type R","Uniprot":["Q15256"],"Chromosome":"12","Position":"70638073-70920738","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.4","endometrium 1":"5.5","intestine":"7.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Excitatory neurons":"196.3","Inhibitory neurons":"156.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"3.6"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"amygdala":"3.7","basal ganglia":"5.7","cerebellum":"14.4","cerebral cortex":"6.5","hippocampal formation":"7.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"11.1","ovarian cancer":"11.8"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebellum":"89.6"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011461","HPA011851","HPA071067"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cell Junctions","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB011461":"AB_298890","HPA011851":"AB_1855939","HPA071067":"AB_2686340"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.40e-5"}},{"Gene":"PTPRS","Gene synonym":[],"Ensembl":"ENSG00000105426","Gene description":"Protein tyrosine phosphatase receptor type S","Uniprot":["Q13332"],"Chromosome":"19","Position":"5158495-5340803","Protein class":["Enzymes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Heparin-binding","Hydrolase","Protein phosphatase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"52.2","Excitatory neurons":"75.7","Horizontal cells":"51.3","Inhibitory neurons":"102.0","Oligodendrocyte precursor cells":"68.8","Oligodendrocytes":"85.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"89","RNA blood cell specific nTPM":{"plasmacytoid DC":"12.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"89","RNA blood lineage specific nTPM":{"dendritic cells":"12.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054747"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA054747":"AB_2682591"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.07e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"}},{"Gene":"PTPRT","Gene synonym":["KIAA0283","RPTPrho"],"Ensembl":"ENSG00000196090","Gene description":"Protein tyrosine phosphatase receptor type T","Uniprot":["O14522"],"Chromosome":"20","Position":"42072752-43189970","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"23.9","fallopian tube":"10.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Excitatory neurons":"493.6","Inhibitory neurons":"681.2","Oligodendrocyte precursor cells":"401.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"breast cancer":"5.1","prostate cancer":"1.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"23.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"1.1","Sarcoma":"2.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Fibroblasts","Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017336","CAB069423"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB069423":"AB_1622602","HPA017336":"AB_1855943"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"}},{"Gene":"PTPRU","Gene synonym":["FMI","hPTP-J","PCP-2","PTP","PTPRO"],"Ensembl":"ENSG00000060656","Gene description":"Protein tyrosine phosphatase receptor type U","Uniprot":["Q92729"],"Chromosome":"1","Position":"29236516-29326813","Protein class":["Enzymes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Differentiation"],"Molecular function":["Hydrolase","Protein phosphatase","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Respiratory ciliated cells":"33.0","Rod photoreceptor cells":"43.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011476","HPA039832"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011476":"AB_442989","HPA039832":"AB_10793923"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.92e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.32e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"}},{"Gene":"PTPRZ1","Gene synonym":["phosphacan","PTP18","PTPRZ","PTPZ","RPTPB"],"Ensembl":"ENSG00000106278","Gene description":"Protein tyrosine phosphatase receptor type Z1","Uniprot":["P23471"],"Chromosome":"7","Position":"121873089-122062036","Protein class":["Enzymes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"88.4","skin 1":"31.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"2599.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"glioma":"175.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"30.7"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Enteric glia cells","Prostate - Urothelial cells","Skin - Keratinocyte (other)","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015103"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA015103":"AB_1855946"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.36e-4"}},{"Gene":"PTTG1IP","Gene synonym":["C21orf1","C21orf3","PBF"],"Ensembl":"ENSG00000183255","Gene description":"PTTG1 interacting protein","Uniprot":["P53801"],"Chromosome":"21","Position":"44849585-44873903","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Heart muscle - Macrophages","Lung - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034146","HPA061827"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"26000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB034146":"AB_1568894","HPA061827":"AB_2684620"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.61e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.28e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.40e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"}},{"Gene":"PUDP","Gene synonym":["DXF68S1E","FAM16AX","GS1","HDHD1","HDHD1A"],"Ensembl":"ENSG00000130021","Gene description":"Pseudouridine 5'-phosphatase","Uniprot":["Q08623"],"Chromosome":"X","Position":"6667865-7148158","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Nucleotide metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"49.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000292","HPA072672"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA000292":null,"HPA072672":"AB_2732208"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.27e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.80e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"}},{"Gene":"PVR","Gene synonym":["CD155","HVED","Necl-5","NECL5","PVS","Tage4"],"Ensembl":"ENSG00000073008","Gene description":"PVR cell adhesion molecule","Uniprot":["P15151"],"Chromosome":"19","Position":"44643798-44666162","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"52.0","Exocrine glandular cells":"57.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"4.5","intermediate monocyte":"4.5","myeloid DC":"3.8","non-classical monocyte":"5.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"3.8","monocytes":"5.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012568","HPA064739"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"720000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm","Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA012568":"AB_1846248","HPA064739":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.30e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.75e-4"}},{"Gene":"PVRIG","Gene synonym":["C7orf15","CD112R","MGC2463"],"Ensembl":"ENSG00000213413","Gene description":"PVR related immunoglobulin domain containing","Uniprot":["Q6DKI7"],"Chromosome":"7","Position":"100218241-100221490","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"10.7","lymphoid tissue":"38.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"3.4","Erythroid cells":"1.1","NK-cells":"3.1","Plasma cells":"1.5","T-cells":"5.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"33","RNA blood cell specific nTPM":{"gdT-cell":"233.3","MAIT T-cell":"277.1","memory B-cell":"139.3","memory CD4 T-cell":"153.0","memory CD8 T-cell":"231.4","naive B-cell":"124.3","naive CD4 T-cell":"169.5","naive CD8 T-cell":"167.1","NK-cell":"263.0","T-reg":"136.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"39","RNA blood lineage specific nTPM":{"B-cells":"139.3","NK-cells":"263.0","T-cells":"277.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"11.8","lymphoma":"24.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047497"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047497":"AB_2680069"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"}},{"Gene":"PXMP2","Gene synonym":["MPV17L3","PMP22"],"Ensembl":"ENSG00000176894","Gene description":"Peroxisomal membrane protein 2","Uniprot":["Q9NR77"],"Chromosome":"12","Position":"132687587-132704985","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"312.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"225.8","Hepatocytes":"630.6","Proximal enterocytes":"357.8","Proximal tubular cells":"258.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"43.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Prostate - Prostate glandular cells","Skin - Sebaceous gland cells","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.84e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.75e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"}},{"Gene":"PXMP4","Gene synonym":["PMP24"],"Ensembl":"ENSG00000101417","Gene description":"Peroxisomal membrane protein 4","Uniprot":["Q9Y6I8"],"Chromosome":"20","Position":"33702758-33720319","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"86.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050077"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Peroxisomes"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA050077":"AB_2681006"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.88e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.03e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"}},{"Gene":"PXN","Gene synonym":[],"Ensembl":"ENSG00000089159","Gene description":"Paxillin","Uniprot":["P49023"],"Chromosome":"12","Position":"120210439-120265771","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"167.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"169.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003841","HPA051309"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Focal adhesion sites","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"CAB003841":"AB_562188","HPA051309":"AB_2681436"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.72e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.12e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"}},{"Gene":"QARS1","Gene synonym":["QARS"],"Ensembl":"ENSG00000172053","Gene description":"Glutaminyl-tRNA synthetase 1","Uniprot":["P47897"],"Chromosome":"3","Position":"49095932-49105130","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Epilepsy","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"578.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Prostate - Prostate basal glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036986","HPA036987"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036986":"AB_10672344","HPA036987":"AB_2675418"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.43e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.60e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"}},{"Gene":"QPCTL","Gene synonym":["FLJ20084"],"Ensembl":"ENSG00000011478","Gene description":"Glutaminyl-peptide cyclotransferase like","Uniprot":["Q9NXS2"],"Chromosome":"19","Position":"45692403-45703989","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"6.4","Plasma cells":"10.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040797"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA040797":"AB_10794148"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.15e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"}},{"Gene":"QRFP","Gene synonym":["26RFa","P518"],"Ensembl":"ENSG00000188710","Gene description":"Pyroglutamylated RFamide peptide","Uniprot":["P83859"],"Chromosome":"9","Position":"130892707-130896812","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":["Neuropeptide"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.8","Horizontal cells":"1.9","Prostatic glandular cells":"1.1","Rod photoreceptor cells":"1.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"monocytes":"1.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043377"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043377":"AB_10959754"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-3"}},{"Gene":"QRFPR","Gene synonym":["GPR103"],"Ensembl":"ENSG00000186867","Gene description":"Pyroglutamylated RFamide peptide receptor","Uniprot":["Q96P65"],"Chromosome":"4","Position":"121328642-121381059","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"5.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"7.3","Early spermatids":"2.3","Endothelial cells":"2.8","Excitatory neurons":"5.7","Inhibitory neurons":"10.7","Microglial cells":"2.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"renal cancer":"5.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"3.9","Kidney cancer":"4.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050236"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050236":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"QRSL1","Gene synonym":["DKFZP564C1278","FLJ10989","FLJ12189","FLJ13447","GatA"],"Ensembl":"ENSG00000130348","Gene description":"Glutaminyl-tRNA amidotransferase subunit QRSL1","Uniprot":["Q9H0R6"],"Chromosome":"6","Position":"106629578-106668417","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Ligase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"68.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"memory B-cell":"86.4","naive B-cell":"71.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"86.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029585","HPA029587"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA029585":"AB_10599823","HPA029587":"AB_10602311"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.97e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"}},{"Gene":"QSOX1","Gene synonym":["QSCN6"],"Ensembl":"ENSG00000116260","Gene description":"Quiescin sulfhydryl oxidase 1","Uniprot":["O00391"],"Chromosome":"1","Position":"180154869-180204030","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"1885.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056243"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2600000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA056243":"AB_2683077"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.86e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"}},{"Gene":"QSOX2","Gene synonym":["DKFZp762A2013","QSCN6L1","SOXN"],"Ensembl":"ENSG00000165661","Gene description":"Quiescin sulfhydryl oxidase 2","Uniprot":["Q6ZRP7"],"Chromosome":"9","Position":"136206333-136245812","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatogonia":"23.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012716","HPA017280"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9600000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA012716":"AB_2173315","HPA017280":"AB_2669565"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.64e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"}},{"Gene":"QTRT1","Gene synonym":["TGT"],"Ensembl":"ENSG00000213339","Gene description":"Queuine tRNA-ribosyltransferase catalytic subunit 1","Uniprot":["Q9BXR0"],"Chromosome":"19","Position":"10701430-10713437","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"185.9","Enteroendocrine cells":"223.4","Paneth cells":"218.8","Proximal enterocytes":"260.7","Undifferentiated cells":"259.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042695","HPA048651","HPA049440"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA042695":"AB_2678119","HPA048651":"AB_2680477","HPA049440":"AB_2680767"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.63e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.90e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.13e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"}},{"Gene":"QTRT2","Gene synonym":["FLJ12960","QTRTD1"],"Ensembl":"ENSG00000151576","Gene description":"Queuine tRNA-ribosyltransferase accessory subunit 2","Uniprot":["Q9H974"],"Chromosome":"3","Position":"114005833-114088422","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036827","HPA036828","HPA070622"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Endoplasmic reticulum","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoli","Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA036827":"AB_2675336","HPA036828":"AB_10696788","HPA070622":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.95e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"}},{"Gene":"R3HCC1","Gene synonym":["DKFZp564N123"],"Ensembl":"ENSG00000104679","Gene description":"R3H domain and coiled-coil containing 1","Uniprot":["Q9Y3T6"],"Chromosome":"8","Position":"23270120-23296279","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"105.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023073","HPA023153"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA023073":"AB_1855987","HPA023153":"AB_2237834"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.08e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.66e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.80e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"}},{"Gene":"RAB18","Gene synonym":[],"Ensembl":"ENSG00000099246","Gene description":"RAB18, member RAS oncogene family","Uniprot":["Q9NP72"],"Chromosome":"10","Position":"27504174-27542239","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction","Protein transport","Transport"],"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025928"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA025928":"AB_1855997"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"}},{"Gene":"RAB3IL1","Gene synonym":["GRAB"],"Ensembl":"ENSG00000167994","Gene description":"RAB3A interacting protein like 1","Uniprot":["Q8TBN0"],"Chromosome":"11","Position":"61897301-61920269","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"57.6","Hofbauer cells":"58.3","Late spermatids":"149.2","Leydig cells":"53.0","Peritubular cells":"43.0","Theca cells":"37.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Heart muscle - Fibroblasts","Lung - Fibroblast_2","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039723"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Centriolar satellite","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039723":"AB_10795406"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.08e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.30e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"}},{"Gene":"RAB5C","Gene synonym":["RAB5CL","RABL"],"Ensembl":"ENSG00000108774","Gene description":"RAB5C, member RAS oncogene family","Uniprot":["P51148"],"Chromosome":"17","Position":"42124978-42155044","Protein class":["Plasma proteins","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Macrophages","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003426","HPA004167"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endosomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"480000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Endosomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA003426":"AB_1079735","HPA004167":"AB_2667156"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.08e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"}},{"Gene":"RAB5IF","Gene synonym":["C20orf24","PNAS-11","RCAF1","RIP5"],"Ensembl":"ENSG00000101084","Gene description":"RAB5 interacting factor","Uniprot":["Q9BUV8"],"Chromosome":"20","Position":"36605779-36612557","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"216.9"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Neutrophil_2"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057387","HPA076106"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA057387":"AB_2683425","HPA076106":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.56e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.46e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"}},{"Gene":"RABAC1","Gene synonym":["PRA1","PRAF1","YIP3"],"Ensembl":"ENSG00000105404","Gene description":"Rab acceptor 1","Uniprot":["Q9UI14"],"Chromosome":"19","Position":"41956681-41959321","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019320","HPA029171"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB019320":null,"HPA029171":"AB_10602121"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"}},{"Gene":"RABGGTA","Gene synonym":["PTAR3"],"Ensembl":"ENSG00000100949","Gene description":"Rab geranylgeranyltransferase subunit alpha","Uniprot":["Q92696"],"Chromosome":"14","Position":"24265538-24271611","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Prenyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"59.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043488"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043488":"AB_10794887"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.51e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"}},{"Gene":"RAC1","Gene synonym":["p21-Rac1","Rac-1","TC-25"],"Ensembl":"ENSG00000136238","Gene description":"Rac family small GTPase 1","Uniprot":["P63000"],"Chromosome":"7","Position":"6374527-6403967","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Endothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB035994","HPA047820"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3900000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB035994":null,"HPA047820":"AB_2680167"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.74e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.59e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.57e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-3"}},{"Gene":"RAD51B","Gene synonym":["hREC2","R51H2","RAD51L1","REC2"],"Ensembl":"ENSG00000182185","Gene description":"RAD51 paralog B","Uniprot":["O15315"],"Chromosome":"14","Position":"67819779-68730218","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA recombination","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Astrocytes":"146.1","Microglial cells":"256.3","Oligodendrocyte precursor cells":"150.7","Oligodendrocytes":"354.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016191","HPA051869"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB016191":"AB_2238209","HPA051869":"AB_2681644"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-3"}},{"Gene":"RAD51C","Gene synonym":["FANCO","RAD51L2"],"Ensembl":"ENSG00000108384","Gene description":"RAD51 paralog C","Uniprot":["O43502"],"Chromosome":"17","Position":"58692573-58735611","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA recombination","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"129.0","Spermatocytes":"144.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045198"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cell Junctions","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm","Mitochondria","Cytosol"],"Subcellular additional location":["Vesicles","Cell Junctions"],"Antibody RRID":{"HPA045198":"AB_2679250"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.68e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.33e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"}},{"Gene":"RAD54L2","Gene synonym":["ARIP4","KIAA0809","SRISNF2L"],"Ensembl":"ENSG00000164080","Gene description":"RAD54 like 2","Uniprot":["Q9Y4B4"],"Chromosome":"3","Position":"51541144-51668667","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035004","HPA039992","HPA077351"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA035004":"AB_10671930","HPA039992":"AB_2676789","HPA077351":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.71e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"}},{"Gene":"RAET1E","Gene synonym":["bA350J20.7","LETAL","ULBP4"],"Ensembl":"ENSG00000164520","Gene description":"Retinoic acid early transcript 1E","Uniprot":["Q8TD07"],"Chromosome":"6","Position":"149883375-149898102","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"21.9","esophagus":"62.8","skin 1":"21.6","vagina":"27.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"93.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"3.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"28.1"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Podocytes","Skin - Keratinocyte (other)","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054022"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Focal adhesion sites","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA054022":"AB_2797250"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"RAET1G","Gene synonym":["ULBP5"],"Ensembl":"ENSG00000203722","Gene description":"Retinoic acid early transcript 1G","Uniprot":["Q6H3X3"],"Chromosome":"6","Position":"149916878-149923121","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Host-virus interaction","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"8.4","esophagus":"15.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"41.4","Respiratory ciliated cells":"20.6","Suprabasal keratinocytes":"40.3","Thymic epithelial cells":"52.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"4.5","head and neck cancer":"4.7","lung cancer":"1.2","thyroid cancer":"1.5","urothelial cancer":"4.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"23.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062673","HPA066741"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA062673":null,"HPA066741":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.35e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"}},{"Gene":"RAET1L","Gene synonym":[],"Ensembl":"ENSG00000155918","Gene description":"Retinoic acid early transcript 1L","Uniprot":["Q5VY80"],"Chromosome":"6","Position":"150018334-150025532","Protein class":["Predicted membrane proteins"],"Biological process":["Host-virus interaction","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"58.1","vagina":"17.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"9.6","Basal respiratory cells":"5.3","Collecting duct cells":"11.8","Squamous epithelial cells":"8.1","Suprabasal keratinocytes":"34.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"4.8","head and neck cancer":"10.1","lung cancer":"4.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"20.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066741"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA066741":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.09e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-3"}},{"Gene":"RALGAPA1","Gene synonym":["DKFZp667F074","GARNL1","GRIPE","KIAA0884","RalGAPalpha1","Tulip1"],"Ensembl":"ENSG00000174373","Gene description":"Ral GTPase activating protein catalytic subunit alpha 1","Uniprot":["Q6GYQ0"],"Chromosome":"14","Position":"35538352-35809304","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"212.1","Inhibitory neurons":"228.5","Oligodendrocyte precursor cells":"229.1","Oligodendrocytes":"389.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000851"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA000851":"AB_1078945"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.76e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"}},{"Gene":"RALGAPA2","Gene synonym":["AS250","C20orf74","dJ1049G11.4","KIAA1272","RapGAPalpha2"],"Ensembl":"ENSG00000188559","Gene description":"Ral GTPase activating protein catalytic subunit alpha 2","Uniprot":["Q2PPJ7"],"Chromosome":"20","Position":"20389530-20712644","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"205.6","Microglial cells":"141.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042707","HPA043622"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042707":"AB_2678124","HPA043622":"AB_2678585"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"}},{"Gene":"RAMP1","Gene synonym":[],"Ensembl":"ENSG00000132329","Gene description":"Receptor activity modifying protein 1","Uniprot":["O60894"],"Chromosome":"2","Position":"237858893-237912106","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"706.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"209.4","Endometrial stromal cells":"610.8","Prostatic glandular cells":"190.1","Skeletal myocytes":"290.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"152.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"18","RNA blood cell specific nTPM":{"NK-cell":"70.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"NK-cells":"70.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"149.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Lung - Smooth muscle cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057814"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA057814":"AB_2683536"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.61e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.68e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"}},{"Gene":"RAMP2","Gene synonym":[],"Ensembl":"ENSG00000131477","Gene description":"Receptor activity modifying protein 2","Uniprot":["O60895"],"Chromosome":"17","Position":"42758447-42763041","Protein class":["FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"1030.8","Endothelial cells":"589.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"21","RNA blood cell specific nTPM":{"plasmacytoid DC":"2.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"dendritic cells":"2.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"24.2"},"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Skin - Fibroblast_2","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052020"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA052020":"AB_2681697"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"RAMP3","Gene synonym":[],"Ensembl":"ENSG00000122679","Gene description":"Receptor activity modifying protein 3","Uniprot":["O60896"],"Chromosome":"7","Position":"45157791-45186302","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"144.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"318.2","Endothelial cells":"301.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"22","RNA cell line specific nTPM":{"Bone cancer":"13.2"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Sinusoid Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"cerebellum":"62.2","cerebral cortex":"49.2","thalamus":"174.9","white matter":"60.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075527"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA075527":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.89e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.50e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"}},{"Gene":"RAN","Gene synonym":["ARA24","Gsp1","TC4"],"Ensembl":"ENSG00000132341","Gene description":"RAN, member RAS oncogene family","Uniprot":["P62826"],"Chromosome":"12","Position":"130872037-130877678","Protein class":["Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":["Cell cycle","Cell division","Host-virus interaction","Mitosis","Protein transport","Transport"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"1324.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063353"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4000000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA063353":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.99e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.86e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.46e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"}},{"Gene":"RANBP17","Gene synonym":[],"Ensembl":"ENSG00000204764","Gene description":"RAN binding protein 17","Uniprot":["Q9H2T7"],"Chromosome":"5","Position":"170861870-171300015","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"130.9","Excitatory neurons":"98.8","Inhibitory neurons":"148.8","Oligodendrocyte precursor cells":"62.6","Oligodendrocytes":"82.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029568","HPA029569"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Nuclear membrane","Cytosol"],"Antibody RRID":{"HPA029568":"AB_10599825","HPA029569":"AB_10601571"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"}},{"Gene":"RAPGEF2","Gene synonym":["DKFZP586O1422","KIAA0313","PDZ-GEF1","PDZGEF1","RA-GEF"],"Ensembl":"ENSG00000109756","Gene description":"Rap guanine nucleotide exchange factor 2","Uniprot":["Q9Y4G8"],"Chromosome":"4","Position":"159103013-159360174","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","GTPase activation","Guanine-nucleotide releasing factor"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"450.0","Inhibitory neurons":"258.1","Microglial cells":"232.6","Oligodendrocyte precursor cells":"190.6","Oligodendrocytes":"223.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"5.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"5.9","NK-cells":"3.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068798"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA068798":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.76e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"}},{"Gene":"RAPGEF6","Gene synonym":["PDZ-GEF2","PDZGEF2","RA-GEF-2"],"Ensembl":"ENSG00000158987","Gene description":"Rap guanine nucleotide exchange factor 6","Uniprot":["Q8TEU7"],"Chromosome":"5","Position":"131423921-131635231","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Astrocytes":"115.5","Excitatory neurons":"239.2","Inhibitory neurons":"248.0","Microglial cells":"177.9","Oligodendrocyte precursor cells":"181.0","Oligodendrocytes":"452.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037982","HPA037983"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA037982":"AB_10670535","HPA037983":"AB_2675769"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-4"}},{"Gene":"RASGEF1B","Gene synonym":["FLJ31695","GPIG4"],"Ensembl":"ENSG00000138670","Gene description":"RasGEF domain family member 1B","Uniprot":["Q0VAM2"],"Chromosome":"4","Position":"81426393-82044244","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"175.6","Langerhans cells":"324.8","Macrophages":"159.6","monocytes":"269.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"11.9","memory B-cell":"9.7","naive B-cell":"12.4","non-classical monocyte":"20.6","plasmacytoid DC":"28.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"12.4","dendritic cells":"28.0","monocytes":"20.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044574"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA044574":"AB_10794292"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.40e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.49e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"}},{"Gene":"RB1","Gene synonym":["OSRC","PPP1R130","RB"],"Ensembl":"ENSG00000139687","Gene description":"RB transcriptional corepressor 1","Uniprot":["P06400"],"Chromosome":"13","Position":"48303744-48599436","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"252.8","Melanocytes":"282.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000095","CAB016687","HPA050082"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000095":null,"CAB016687":"AB_1622010","HPA050082":"AB_2681008"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.92e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"}},{"Gene":"RBCK1","Gene synonym":["C20orf18","HOIL1","RBCK2","RNF54","UBCE7IP3","XAP4","ZRANB4"],"Ensembl":"ENSG00000125826","Gene description":"RANBP2-type and C3HC4-type zinc finger containing 1","Uniprot":["Q9BYM8"],"Chromosome":"20","Position":"407498-432139","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.41e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-3"}},{"Gene":"RBFOX3","Gene synonym":["FOX-3","HRNBP3","NeuN"],"Ensembl":"ENSG00000167281","Gene description":"RNA binding fox-1 homolog 3","Uniprot":["A6NFN3"],"Chromosome":"17","Position":"79089345-79516148","Protein class":["Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"217.2","intestine":"97.4","urinary bladder":"80.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"316.0","Inhibitory neurons":"159.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"1.1"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"217.2","cerebral cortex":"118.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"8.8","Neuroblastoma":"15.0"},"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030790","HPA075862","CAB078782"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB078782":null,"HPA030790":"AB_10602305","HPA075862":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"}},{"Gene":"RBL1","Gene synonym":["cp107","p107","PRB1"],"Ensembl":"ENSG00000080839","Gene description":"RB transcriptional corepressor like 1","Uniprot":["P28749"],"Chromosome":"20","Position":"36996349-37095997","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Repressor"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"14.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"22.1","Inhibitory neurons":"22.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Skin - Mitotic cells (Skin)","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054962","HPA056525"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA054962":"AB_2682652","HPA056525":"AB_2683165"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"}},{"Gene":"RBM14","Gene synonym":["COAA","DKFZp779J0927","SIP","SYTIP1"],"Ensembl":"ENSG00000239306","Gene description":"RNA binding motif protein 14","Uniprot":["Q96PK6"],"Chromosome":"11","Position":"66616626-66629934","Protein class":["Predicted intracellular proteins"],"Biological process":["Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["Repressor","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006628"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"31000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA006628":"AB_1078546"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"}},{"Gene":"RBM34","Gene synonym":["KIAA0117"],"Ensembl":"ENSG00000188739","Gene description":"RNA binding motif protein 34","Uniprot":["P42696"],"Chromosome":"1","Position":"235131183-235161283","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028606"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Mitotic chromosome"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm","Mitotic chromosome"],"Antibody RRID":{"HPA028606":"AB_10601494"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-4"}},{"Gene":"RCAN2","Gene synonym":["DSCR1L1","ZAKI-4"],"Ensembl":"ENSG00000172348","Gene description":"Regulator of calcineurin 2","Uniprot":["Q14206"],"Chromosome":"6","Position":"46220736-46491972","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"199.5","tongue":"180.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"249.0","Excitatory neurons":"257.7","Inhibitory neurons":"248.4","Muller glia cells":"172.2","Oligodendrocytes":"278.1","Smooth muscle cells":"123.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"25.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"17","RNA blood cell specific nTPM":{"gdT-cell":"1.8","memory CD4 T-cell":"1.1","memory CD8 T-cell":"2.2","naive CD8 T-cell":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"T-cells":"2.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"15.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Lung - Smooth muscle cells","Skin - Eccrine sweat gland cells","Testis - Peritubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053880"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA053880":"AB_2682290"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.48e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"}},{"Gene":"RCE1","Gene synonym":["FACE-2","FACE2","hRCE1","RCE1A","RCE1B"],"Ensembl":"ENSG00000173653","Gene description":"Ras converting CAAX endopeptidase 1","Uniprot":["Q9Y256"],"Chromosome":"11","Position":"66842835-66846552","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"70.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074124"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074124":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"}},{"Gene":"RCL1","Gene synonym":["RNAC","RPCL1"],"Ensembl":"ENSG00000120158","Gene description":"RNA terminal phosphate cyclase like 1","Uniprot":["Q9Y2P8"],"Chromosome":"9","Position":"4792944-4885917","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Ribosome biogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"245.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"71.9","Hepatocytes":"199.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071308"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA071308":"AB_2686384"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.48e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.02e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.40e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"}},{"Gene":"RCN3","Gene synonym":["RLP49"],"Ensembl":"ENSG00000142552","Gene description":"Reticulocalbin 3","Uniprot":["Q96D15"],"Chromosome":"19","Position":"49528003-49546962","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"55.3","Fibroblasts":"112.2","Leydig cells":"38.9","Pancreatic endocrine cells":"60.1","Peritubular cells":"43.0","Smooth muscle cells":"33.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"6.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"2.5","NK-cells":"1.8","T-cells":"6.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"129.1","Sarcoma":"126.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Heart muscle - Fibroblasts","Lung - Fibroblast_2","Prostate - Fibroblasts","Skin - Fibroblast_2","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043134","HPA050402"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA043134":"AB_2678332","HPA050402":"AB_2681114"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.80e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-3"}},{"Gene":"RDH10","Gene synonym":["SDR16C4"],"Ensembl":"ENSG00000121039","Gene description":"Retinol dehydrogenase 10","Uniprot":["Q8IZV5"],"Chromosome":"8","Position":"73294602-73325281","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"173.3","Ionocytes":"213.5","Muller glia cells":"316.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049199"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Lipid droplets"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"HPA049199":"AB_2680673"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"}},{"Gene":"RDH16","Gene synonym":["RODH-4","SDR9C8"],"Ensembl":"ENSG00000139547","Gene description":"Retinol dehydrogenase 16","Uniprot":["O75452"],"Chromosome":"12","Position":"56951431-56959374","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Steroid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"152","RNA tissue specific nTPM":{"liver":"793.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"344.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"20","RNA cancer specific FPKM":{"liver cancer":"44.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"1.6","prostate cancer":"1.6"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038518"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038518":"AB_10672713"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.16e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"}},{"Gene":"RDM1","Gene synonym":["MGC33977","RAD52B"],"Ensembl":"ENSG00000278023","Gene description":"RAD52 motif containing 1","Uniprot":["Q8NG50"],"Chromosome":"17","Position":"35918066-35930773","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["DNA-binding","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"11.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"38.7","Late spermatids":"95.9","Spermatocytes":"23.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory CD8 T-cell":"2.6"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"T-cells":"2.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Mitotic cells (Stomach)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024794","HPA067546"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA024794":"AB_1856039","HPA067546":"AB_2732769"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"}},{"Gene":"RECK","Gene synonym":["hRECK","ST15"],"Ensembl":"ENSG00000122707","Gene description":"Reversion inducing cysteine rich protein with kazal motifs","Uniprot":["O95980"],"Chromosome":"9","Position":"36036913-36124455","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"62.3","Inhibitory neurons":"69.6","Oligodendrocyte precursor cells":"77.0","Oligodendrocytes":"113.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Colon - Fibroblasts","Lung - Fibroblast_1","Prostate - Fibroblasts","Testis - Early spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025109","HPA071729"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"64000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB025109":null,"HPA071729":"AB_2686438"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.31e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"}},{"Gene":"REELD1","Gene synonym":[],"Ensembl":"ENSG00000250673","Gene description":"Reeler domain containing 1","Uniprot":["A0A1B0GV85"],"Chromosome":"4","Position":"146214515-146230878","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"2.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"}},{"Gene":"REEP1","Gene synonym":["C2orf23","FLJ13110","SPG31","Yip2a"],"Ensembl":"ENSG00000068615","Gene description":"Receptor accessory protein 1","Uniprot":["Q9H902"],"Chromosome":"2","Position":"86213993-86338083","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"50.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"85.0","Inhibitory neurons":"93.2","Oligodendrocyte precursor cells":"37.5","Sertoli cells":"96.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"7.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Mesothelial cells","Liver - Sinusoid Endothelial cells","Prostate - Smooth muscle cells","Skin - Smooth muscle cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058061"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058061":"AB_2683591"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"}},{"Gene":"REEP2","Gene synonym":["C5orf19","SGC32445","SPG72","Yip2d"],"Ensembl":"ENSG00000132563","Gene description":"Receptor accessory protein 2","Uniprot":["Q9BRK0"],"Chromosome":"5","Position":"138439057-138446969","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"155.7","choroid plexus":"77.8","retina":"61.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"43.7","Cone photoreceptor cells":"155.1","Excitatory neurons":"50.4","Horizontal cells":"62.2","Inhibitory neurons":"45.1","Rod photoreceptor cells":"60.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"31.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"35.2"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031813","HPA076571"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA031813":"AB_2674054","HPA076571":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.83e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.65e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.31e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"}},{"Gene":"REEP3","Gene synonym":["C10orf74","Yip2b"],"Ensembl":"ENSG00000165476","Gene description":"Receptor accessory protein 3","Uniprot":["Q6NUK4"],"Chromosome":"10","Position":"63521401-63625128","Protein class":["Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"354.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.83e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"}},{"Gene":"REEP4","Gene synonym":["C8orf20","FLJ22246","FLJ22277","PP432","Yip2c"],"Ensembl":"ENSG00000168476","Gene description":"Receptor accessory protein 4","Uniprot":["Q9H6H4"],"Chromosome":"8","Position":"22138020-22141951","Protein class":["Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"89.3","skin 1":"91.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"94.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042683"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA042683":"AB_2571730"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.14e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.88e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"}},{"Gene":"REEP5","Gene synonym":["C5orf18","D5S346","DP1","POB16","TB2","Yip2e"],"Ensembl":"ENSG00000129625","Gene description":"Receptor accessory protein 5","Uniprot":["Q00765"],"Chromosome":"5","Position":"112876385-112922289","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003895","HPA069960"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA003895":"AB_1845723","HPA069960":"AB_2686221"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.23e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.05e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"}},{"Gene":"REEP6","Gene synonym":["C19orf32","DP1L1","FLJ25383","Yip2f"],"Ensembl":"ENSG00000115255","Gene description":"Receptor accessory protein 6","Uniprot":["Q96HR9"],"Chromosome":"19","Position":"1491166-1497927","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"217.5","liver":"398.0","testis":"283.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"3104.1","Proximal enterocytes":"919.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"114.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Breast glandular cells","Breast - Breast glandular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Prostate - Prostate glandular cells","Skin - Sebaceous gland cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003895","HPA048015"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA003895":"AB_1845723","HPA048015":"AB_2680233"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"}},{"Gene":"RELCH","Gene synonym":["FLJ33841","HsT3308","HsT885","KIAA1468"],"Ensembl":"ENSG00000134444","Gene description":"RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing","Uniprot":["Q9P260"],"Chromosome":"18","Position":"62187255-62310249","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"129.3","Inhibitory neurons":"94.9","Microglial cells":"83.9","Oligodendrocyte precursor cells":"106.9","Oligodendrocytes":"165.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate basal glandular cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039708","HPA040038"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Centriolar satellite","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039708":"AB_10794753","HPA040038":"AB_10793860"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"}},{"Gene":"RELL1","Gene synonym":[],"Ensembl":"ENSG00000181826","Gene description":"RELT like 1","Uniprot":["Q8IUW5"],"Chromosome":"4","Position":"37590800-37686376","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"39.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"85.8","dendritic cells":"124.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"59.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013377"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane","Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA013377":"AB_1844403"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"}},{"Gene":"RELL2","Gene synonym":["C5orf16","FLJ90583"],"Ensembl":"ENSG00000164620","Gene description":"RELT like 2","Uniprot":["Q8NC24"],"Chromosome":"5","Position":"141636950-141641064","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"38.2","parathyroid gland":"16.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"20.7","Excitatory neurons":"28.1","Horizontal cells":"48.1","Inhibitory neurons":"28.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077928"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA077928":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"}},{"Gene":"RELT","Gene synonym":["FLJ14993","TNFRSF19L"],"Ensembl":"ENSG00000054967","Gene description":"RELT TNF receptor","Uniprot":["Q969Z4"],"Chromosome":"11","Position":"73376399-73397474","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Receptor"],"Disease involvement":["Amelogenesis imperfecta","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"154.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"53.8","Kupffer cells":"39.1","Langerhans cells":"47.9","Macrophages":"39.4","monocytes":"79.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062824","HPA071518"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA062824":"AB_2684875","HPA071518":"AB_2686408"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.07e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"}},{"Gene":"RENBP","Gene synonym":["RBP","RNBP"],"Ensembl":"ENSG00000102032","Gene description":"Renin binding protein","Uniprot":["P51606"],"Chromosome":"X","Position":"153935269-153944687","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"43.0","lymphoid tissue":"67.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"79.2","Hofbauer cells":"173.9","Macrophages":"44.2","Melanocytes":"50.5","Proximal tubular cells":"167.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"57.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2.7","monocytes":"1.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"20.6","Myeloma":"22.9","skin cancer":"50.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Lung - Macrophages","Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000428","HPA000522"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000428":"AB_1079799","HPA000522":"AB_1079798"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.95e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.08e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"}},{"Gene":"RER1","Gene synonym":[],"Ensembl":"ENSG00000157916","Gene description":"Retention in endoplasmic reticulum sorting receptor 1","Uniprot":["O15258"],"Chromosome":"1","Position":"2391775-2405442","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"510.7","Syncytiotrophoblasts":"526.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037240","HPA051400"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB037240":"AB_2179604","HPA051400":"AB_2681469"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.23e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"}},{"Gene":"RET","Gene synonym":["CDHF12","CDHR16","HSCR1","MEN2A","MEN2B","MTC1","PTC","RET51"],"Ensembl":"ENSG00000165731","Gene description":"Ret proto-oncogene","Uniprot":["P07949"],"Chromosome":"10","Position":"43077064-43130351","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Hirschsprung disease","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"20.8","brain":"27.3","parathyroid gland":"31.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"dendritic cells":"48.0","Horizontal cells":"28.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"11.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Neuroblastoma":"120.9","thyroid cancer":"39.8"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"midbrain":"53.3","spinal cord":"19.4"},"Antibody":["CAB002581","HPA008356","HPA008495"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB002581":"AB_563673","HPA008356":"AB_1847232","HPA008495":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.02e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"}},{"Gene":"RETREG1","Gene synonym":["FAM134B","FLJ20152","JK1"],"Ensembl":"ENSG00000154153","Gene description":"Reticulophagy regulator 1","Uniprot":["Q9H6L5"],"Chromosome":"5","Position":"16473038-16617038","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"91.4","skeletal muscle":"141.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"246.8","Early spermatids":"454.1","Glandular and luminal cells":"242.4","Late spermatids":"727.6","Oligodendrocytes":"276.6","Skeletal myocytes":"254.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"28.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.3","T-cells":"1.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012077"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA012077":"AB_2668621"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"}},{"Gene":"RETREG2","Gene synonym":["C2orf17","FAM134A","MAG-2","MGC3035"],"Ensembl":"ENSG00000144567","Gene description":"Reticulophagy regulator family member 2","Uniprot":["Q8NC44"],"Chromosome":"2","Position":"219176225-219185475","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"161.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011170","HPA011844","HPA075910"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA011170":"AB_1845713","HPA011844":"AB_2668544","HPA075910":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.95e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"}},{"Gene":"RETREG3","Gene synonym":["DKFZp686B1036","FAM134C","FLJ33806"],"Ensembl":"ENSG00000141699","Gene description":"Reticulophagy regulator family member 3","Uniprot":["Q86VR2"],"Chromosome":"17","Position":"42579513-42610623","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"90.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016492"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA016492":"AB_1853027"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.82e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"}},{"Gene":"REV1","Gene synonym":["REV1L"],"Ensembl":"ENSG00000135945","Gene description":"REV1 DNA directed polymerase","Uniprot":["Q9UBZ9"],"Chromosome":"2","Position":"99400475-99490035","Protein class":["Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","DNA synthesis"],"Molecular function":["DNA-binding","Nucleotidyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008881","HPA044534","HPA051036"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA008881":null,"HPA044534":"AB_2678975","HPA051036":"AB_2681319"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.03e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"}},{"Gene":"RFT1","Gene synonym":["CDG1N"],"Ensembl":"ENSG00000163933","Gene description":"RFT1 homolog","Uniprot":["Q96AA3"],"Chromosome":"3","Position":"53088483-53130453","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"41.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060327","HPA069022"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA060327":"AB_2684253","HPA069022":"AB_2732126"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.69e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"}},{"Gene":"RGMA","Gene synonym":["RGM"],"Ensembl":"ENSG00000182175","Gene description":"Repulsive guidance molecule BMP co-receptor a","Uniprot":["Q96B86"],"Chromosome":"15","Position":"93035273-93089204","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"126.3","skeletal muscle":"199.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"138.9","Basal squamous epithelial cells":"44.6","Leydig cells":"118.0","Peritubular cells":"115.2","Skeletal myocytes":"51.5","Spermatogonia":"46.2","Squamous epithelial cells":"59.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"26.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"11.9","Sarcoma":"9.5"},"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Lung - Fibroblast_2","Skin - Outer root sheath cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012343","HPA039880","HPA044222"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB012343":"AB_777667","HPA039880":"AB_2676723","HPA044222":"AB_2678861"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.78e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-5"}},{"Gene":"RGMB","Gene synonym":["DRAGON","FLJ90406"],"Ensembl":"ENSG00000174136","Gene description":"Repulsive guidance molecule BMP co-receptor b","Uniprot":["Q6NW40"],"Chromosome":"5","Position":"98768650-98798643","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"56.1","Undifferentiated cells":"104.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"3.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"B-cells":"1.6","T-cells":"3.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016993"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"560000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA016993":"AB_1856216"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-3"}},{"Gene":"RGR","Gene synonym":["RP44"],"Ensembl":"ENSG00000148604","Gene description":"Retinal G protein coupled receptor","Uniprot":["P47804"],"Chromosome":"10","Position":"84230666-84259960","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"retina":"139.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"40","RNA single cell type specific nTPM":{"Muller glia cells":"1379.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"midbrain":"23.4","olfactory bulb":"49.7","thalamus":"27.3"},"Antibody":["HPA059149"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA059149":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"RGS9BP","Gene synonym":["FLJ45744","PERRS","R9AP"],"Ensembl":"ENSG00000186326","Gene description":"Regulator of G protein signaling 9 binding protein","Uniprot":["Q6ZS82"],"Chromosome":"19","Position":"32675848-32678300","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Signal transduction inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"choroid plexus":"28.9","retina":"17.4","skeletal muscle":"9.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Bipolar cells":"31.8","Cone photoreceptor cells":"93.1","Rod photoreceptor cells":"68.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049791"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA049791":"AB_2680884"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"}},{"Gene":"RHAG","Gene synonym":["CD241","RH50A","SLC42A1"],"Ensembl":"ENSG00000112077","Gene description":"Rh associated glycoprotein","Uniprot":["Q02094"],"Chromosome":"6","Position":"49605175-49636839","Protein class":["CD markers","Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ammonia transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"54","RNA tissue specific nTPM":{"bone marrow":"119.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Erythroid cells":"370.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"103.0"},"RNA tissue cell type enrichment":["Liver - Erythroid cells","Lung - Neutrophil_1"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046051","HPA055331"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA046051":null,"HPA055331":"AB_2682785"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"RHBDD1","Gene synonym":["DKFZp547E052"],"Ensembl":"ENSG00000144468","Gene description":"Rhomboid domain containing 1","Uniprot":["Q8TEB9"],"Chromosome":"2","Position":"226835581-226999215","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Differentiation","Spermatogenesis"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"64.8","Microglial cells":"55.6","Oligodendrocyte precursor cells":"53.4","Oligodendrocytes":"102.9","Plasma cells":"51.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013972","HPA057125"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA013972":"AB_2178629","HPA057125":"AB_2683343"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"}},{"Gene":"RHBDD2","Gene synonym":["NPD007","RHBDL7"],"Ensembl":"ENSG00000005486","Gene description":"Rhomboid domain containing 2","Uniprot":["Q6NTF9"],"Chromosome":"7","Position":"75842602-75888926","Protein class":["Enzymes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"380.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"300.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"398.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045074","HPA051960"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA045074":"AB_10965705","HPA051960":"AB_2681673"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.31e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.81e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.68e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"}},{"Gene":"RHBDD3","Gene synonym":["C22orf3","PTAG"],"Ensembl":"ENSG00000100263","Gene description":"Rhomboid domain containing 3","Uniprot":["Q9Y3P4"],"Chromosome":"22","Position":"29259872-29268209","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043979"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA043979":"AB_10960539"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.67e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-3"}},{"Gene":"RHBDF1","Gene synonym":["C16orf8","Dist1","EGFR-RS","FLJ2235","iRhom1"],"Ensembl":"ENSG00000007384","Gene description":"Rhomboid 5 homolog 1","Uniprot":["Q96CC6"],"Chromosome":"16","Position":"58059-76355","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Growth factor binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Schwann cells":"41.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077399"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA077399":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"}},{"Gene":"RHBDF2","Gene synonym":["FLJ22341","iRhom2","RHBDL5","RHBDL6","TOC","TOCG"],"Ensembl":"ENSG00000129667","Gene description":"Rhomboid 5 homolog 2","Uniprot":["Q6PJF5"],"Chromosome":"17","Position":"76470891-76501790","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Growth factor binding"],"Disease involvement":["Disease variant","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"61.0","Ionocytes":"56.5","Kupffer cells":"77.7","Langerhans cells":"56.1","Macrophages":"53.9","monocytes":"55.0","NK-cells":"64.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018080"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018080":"AB_2178634"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.96e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"}},{"Gene":"RHBDL1","Gene synonym":["RHBDL","RRP"],"Ensembl":"ENSG00000103269","Gene description":"Rhomboid like 1","Uniprot":["O75783"],"Chromosome":"16","Position":"675671-678268","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"17.7","Excitatory neurons":"29.7","Horizontal cells":"34.0","Inhibitory neurons":"26.5","Rod photoreceptor cells":"36.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030359","HPA030360","HPA046593"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA030359":"AB_2673445","HPA030360":"AB_2673446","HPA046593":"AB_2679711"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.12e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"}},{"Gene":"RHBDL2","Gene synonym":["FLJ20435"],"Ensembl":"ENSG00000158315","Gene description":"Rhomboid like 2","Uniprot":["Q9NX52"],"Chromosome":"1","Position":"38885807-38941830","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"24.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"74.4","Club cells":"47.8","Distal enterocytes":"54.2","Ionocytes":"52.0","Oligodendrocytes":"50.9","Suprabasal keratinocytes":"45.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Urothelial cells","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043807"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043807":"AB_10961118"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"}},{"Gene":"RHBDL3","Gene synonym":["RHBDL4","VRHO"],"Ensembl":"ENSG00000141314","Gene description":"Rhomboid like 3","Uniprot":["P58872"],"Chromosome":"17","Position":"32265832-32324659","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"23.0","heart muscle":"13.8","retina":"26.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"40.5","Cone photoreceptor cells":"19.0","Excitatory neurons":"46.2","Horizontal cells":"38.5","Oligodendrocyte precursor cells":"72.7","Rod photoreceptor cells":"35.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"4.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Podocytes","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059607"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059607":"AB_2684081"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"}},{"Gene":"RHBG","Gene synonym":["SLC42A2"],"Ensembl":"ENSG00000132677","Gene description":"Rh family B glycoprotein","Uniprot":["Q9H310"],"Chromosome":"1","Position":"156369211-156385219","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ammonia transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"kidney":"9.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"17.7","Distal tubular cells":"24.9","Granulosa cells":"89.9","Late spermatids":"15.5","Theca cells":"63.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"14.2","renal cancer":"5.1","urothelial cancer":"4.1"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"17","RNA brain regional specific nTPM":{"cerebellum":"2.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Liver - Hepatocytes","Pancreas - Exocrine glandular cells","Skin - Keratinocyte (granular)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042726","HPA048489"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA042726":"AB_2678131","HPA048489":"AB_2680417"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.06e-4"}},{"Gene":"RHCE","Gene synonym":["CD240CE","RH"],"Ensembl":"ENSG00000188672","Gene description":"Rh blood group CcEe antigens","Uniprot":["P18577"],"Chromosome":"1","Position":"25362249-25430192","Protein class":["Blood group antigen proteins","CD markers","Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Blood group antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"bone marrow":"48.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"33","RNA single cell type specific nTPM":{"Erythroid cells":"256.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"5.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060951","HPA077385"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA060951":null,"HPA077385":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"}},{"Gene":"RHCG","Gene synonym":["C15orf6","PDRC2","RHGK","SLC42A3"],"Ensembl":"ENSG00000140519","Gene description":"Rh family C glycoprotein","Uniprot":["Q9UBD6"],"Chromosome":"15","Position":"89471398-89496589","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ammonia transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"4022.4","vagina":"1728.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Squamous epithelial cells":"1909.7","Suprabasal keratinocytes":"4570.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"152.9","head and neck cancer":"154.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Gallbladder cancer":"20.4","head and neck cancer":"42.3"},"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"olfactory bulb":"8.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041874","HPA043317"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041874":"AB_2677719","HPA043317":"AB_2678424"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.80e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-3"}},{"Gene":"RHD","Gene synonym":["CD240D","DIIIc","RH","Rh30a","Rh4","RhII","RhPI"],"Ensembl":"ENSG00000187010","Gene description":"Rh blood group D antigen","Uniprot":["Q02161"],"Chromosome":"1","Position":"25272393-25330445","Protein class":["Blood group antigen proteins","CD markers","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Blood group antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"15.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Erythroid cells":"105.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"6.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"6.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"3.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060951","HPA077385"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA060951":null,"HPA077385":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-3"}},{"Gene":"RHEX","Gene synonym":["C1orf186","FLJ16052"],"Ensembl":"ENSG00000263961","Gene description":"Regulator of hemoglobinization and erythroid cell expansion","Uniprot":["Q6ZWK4"],"Chromosome":"1","Position":"206053173-206102449","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Erythrocyte maturation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"24.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"granulocytes":"535.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"endometrial cancer":"42.8","ovarian cancer":"41.1","renal cancer":"27.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"152","RNA blood cell specific nTPM":{"basophil":"1312.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"1544","RNA blood lineage specific nTPM":{"granulocytes":"1312.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"17.5","Leukemia":"56.9","ovarian cancer":"17.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Adipose visceral - Mast cells","Colon - Mast cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037859"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA037859":"AB_10697084"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"}},{"Gene":"RHO","Gene synonym":["CSNBAD1","OPN2","RP4"],"Ensembl":"ENSG00000163914","Gene description":"Rhodopsin","Uniprot":["P08100"],"Chromosome":"3","Position":"129528639-129535344","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":["Congenital stationary night blindness","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5994","RNA tissue specific nTPM":{"retina":"4062.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"3817.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hippocampal formation":"9.7"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"1.1"},"Antibody":["HPA013440","CAB022486","CAB034887","CAB034888"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022486":null,"CAB034887":"AB_785511","CAB034888":"AB_785512","HPA013440":"AB_2668844"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"RHOT1","Gene synonym":["ARHT1","FLJ11040","MIRO-1","MIRO1"],"Ensembl":"ENSG00000126858","Gene description":"Ras homolog family member T1","Uniprot":["Q8IXI2"],"Chromosome":"17","Position":"32142454-32253374","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010687","CAB068223","CAB068224"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB068223":"AB_2665691","CAB068224":"AB_2665692","HPA010687":"AB_1079813"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"}},{"Gene":"RHOT2","Gene synonym":["ARHT2","C16orf39","MIRO-2"],"Ensembl":"ENSG00000140983","Gene description":"Ras homolog family member T2","Uniprot":["Q8IXI1"],"Chromosome":"16","Position":"668105-674174","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"220.6","Rod photoreceptor cells":"300.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012624","HPA012895"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA012624":"AB_1856272","HPA012895":"AB_1856271"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.43e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"}},{"Gene":"RIC1","Gene synonym":["bA207C16.1","KIAA1432"],"Ensembl":"ENSG00000107036","Gene description":"RIC1 homolog, RAB6A GEF complex partner 1","Uniprot":["Q4ADV7"],"Chromosome":"9","Position":"5629025-5776557","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"83.4","Inhibitory neurons":"77.8","Microglial cells":"95.8","Oligodendrocyte precursor cells":"66.9","Oligodendrocytes":"66.6","Plasma cells":"69.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051578"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051578":"AB_2681541"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"}},{"Gene":"RIC3","Gene synonym":["AYST720","FLJ11608","PRO1385"],"Ensembl":"ENSG00000166405","Gene description":"RIC3 acetylcholine receptor chaperone","Uniprot":["Q7Z5B4"],"Chromosome":"11","Position":"8106056-8169055","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"165.3","Horizontal cells":"133.3","Rod photoreceptor cells":"217.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"12.8","granulocytes":"4.5","T-cells":"6.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"6.9"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065016"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA065016":"AB_2685404"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"}},{"Gene":"RLF","Gene synonym":["Zn-15L","ZNF292L"],"Ensembl":"ENSG00000117000","Gene description":"RLF zinc finger","Uniprot":["Q13129"],"Chromosome":"1","Position":"40161387-40240921","Protein class":["Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054653","HPA057300"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA054653":"AB_2682557","HPA057300":"AB_2683404"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.75e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.68e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"}},{"Gene":"RMDN2","Gene synonym":["FAM82A","FAM82A1","FLJ32954","RMD2"],"Ensembl":"ENSG00000115841","Gene description":"Regulator of microtubule dynamics 2","Uniprot":["Q96LZ7"],"Chromosome":"2","Position":"37923187-38067142","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"42.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"258.6","Late spermatids":"183.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034705","HPA034706"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Mitotic spindle","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Mitotic spindle","Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA034705":"AB_2674292","HPA034706":"AB_10696362"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.63e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"}},{"Gene":"RMDN3","Gene synonym":["FAM82A2","FAM82C","FLJ10579","PTPIP51","RMD3"],"Ensembl":"ENSG00000137824","Gene description":"Regulator of microtubule dynamics 3","Uniprot":["Q96TC7"],"Chromosome":"15","Position":"40735884-40755851","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"97.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009975","HPA074840"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytokinetic bridge","Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"42000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA009975":"AB_1078811","HPA074840":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.70e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"}},{"Gene":"RMND1","Gene synonym":["bA351K16.3","C6orf96","FLJ20627","RMD1"],"Ensembl":"ENSG00000155906","Gene description":"Required for meiotic nuclear division 1 homolog","Uniprot":["Q9NWS8"],"Chromosome":"6","Position":"151404762-151452158","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031397","HPA031398","HPA031399"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA031397":"AB_2673861","HPA031398":"AB_2673862","HPA031399":"AB_10601156"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.96e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"RNASE10","Gene synonym":["RAH1","RNASE9"],"Ensembl":"ENSG00000182545","Gene description":"Ribonuclease A family member 10 (inactive)","Uniprot":["Q5GAN6"],"Chromosome":"14","Position":"20505537-20511169","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Fertilization"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"head and neck cancer":"2.0","testis cancer":"1.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052593"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052593":"AB_2681878"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"}},{"Gene":"RNASEK","Gene synonym":["MGC71993"],"Ensembl":"ENSG00000219200","Gene description":"Ribonuclease K","Uniprot":["Q6P5S7"],"Chromosome":"17","Position":"7012417-7014532","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Endocytosis","Hydrogen ion transport","Ion transport","Transport"],"Molecular function":["Endonuclease","Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"237.2","Macrophages":"117.8","Plasma cells":"181.2","Squamous epithelial cells":"247.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044708"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044708":"AB_10962051"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.92e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"}},{"Gene":"RNASEK-C17orf49","Gene synonym":[],"Ensembl":"ENSG00000161939","Gene description":"RNASEK-C17orf49 readthrough","Uniprot":[],"Chromosome":"17","Position":"7012635-7017520","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"6.1","Exocrine glandular cells":"4.3","Pancreatic endocrine cells":"8.6","Proximal enterocytes":"3.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022961","HPA024457"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA022961":"AB_1845592","HPA024457":"AB_1845593"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"}},{"Gene":"RNASET2","Gene synonym":["bA514O12.3","FLJ10907","RNASE6PL"],"Ensembl":"ENSG00000026297","Gene description":"Ribonuclease T2","Uniprot":["O00584"],"Chromosome":"6","Position":"166922113-166957191","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Endonuclease","Hydrolase","Lyase","Nuclease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"779.5","Endometrial ciliated cells":"463.2","Glandular and luminal cells":"788.6","Hofbauer cells":"492.1","monocytes":"545.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"197.2"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029013","HPA066509"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029013":"AB_10602922","HPA066509":"AB_2685682"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"}},{"Gene":"RNF103","Gene synonym":["hkf-1","KF1","ZFP103"],"Ensembl":"ENSG00000239305","Gene description":"Ring finger protein 103","Uniprot":["O00237"],"Chromosome":"2","Position":"86603398-86623866","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"7.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057922"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057922":"AB_2683555"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.77e-5"}},{"Gene":"RNF121","Gene synonym":["FLJ11099"],"Ensembl":"ENSG00000137522","Gene description":"Ring finger protein 121","Uniprot":["Q9H920"],"Chromosome":"11","Position":"71929018-71997597","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046041"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA046041":"AB_10965850"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.72e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"}},{"Gene":"RNF122","Gene synonym":["FLJ12526"],"Ensembl":"ENSG00000133874","Gene description":"Ring finger protein 122","Uniprot":["Q9H9V4"],"Chromosome":"8","Position":"33547754-33567128","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"31.4","dendritic cells":"16.6","Endothelial cells":"13.5","Glandular and luminal cells":"18.0","monocytes":"26.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"35.8"},"RNA tissue cell type enrichment":["Colon - Neutrophils"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003888"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003888":"AB_1079822"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.37e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.50e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.88e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"}},{"Gene":"RNF128","Gene synonym":["FLJ23516","GRAIL"],"Ensembl":"ENSG00000133135","Gene description":"Ring finger protein 128","Uniprot":["Q8TEB7"],"Chromosome":"X","Position":"106693794-106797016","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"62.1","liver":"124.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"42.3","Gastric mucus-secreting cells":"47.7","Hepatocytes":"63.4","Intestinal goblet cells":"42.0","Proximal enterocytes":"74.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Liver - Hepatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019675"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019675":"AB_2670225"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.07e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-3"}},{"Gene":"RNF13","Gene synonym":["RZF"],"Ensembl":"ENSG00000082996","Gene description":"Ring finger protein 13","Uniprot":["O43567"],"Chromosome":"3","Position":"149812770-149962139","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"558.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"462.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064784"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA064784":"AB_2685350"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.00e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"RNF130","Gene synonym":["G1RZFP","GOLIATH","GP"],"Ensembl":"ENSG00000113269","Gene description":"Ring finger protein 130","Uniprot":["Q86XS8"],"Chromosome":"5","Position":"179911651-180072113","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"302.2","Hofbauer cells":"339.6","Macrophages":"298.0","monocytes":"300.9","Oligodendrocytes":"485.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"261.6","classical monocyte":"513.2","eosinophil":"331.3","intermediate monocyte":"355.0","myeloid DC":"407.4","neutrophil":"890.5","non-classical monocyte":"328.7","plasmacytoid DC":"317.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"407.4","granulocytes":"890.5","monocytes":"513.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014499"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014499":"AB_1856328"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.32e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"}},{"Gene":"RNF133","Gene synonym":[],"Ensembl":"ENSG00000188050","Gene description":"Ring finger protein 133","Uniprot":["Q8WVZ7"],"Chromosome":"7","Position":"122697735-122699117","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"42.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"204","RNA single cell type specific nTPM":{"Early spermatids":"369.3","Late spermatids":"906.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"7.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"}},{"Gene":"RNF139","Gene synonym":["HRCA1","RCA1","TRC8"],"Ensembl":"ENSG00000170881","Gene description":"Ring finger protein 139","Uniprot":["Q8WU17"],"Chromosome":"8","Position":"124474880-124488618","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Receptor","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"93.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"650.2","Late spermatids":"1136.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001202"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001202":"AB_1079824"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.54e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"}},{"Gene":"RNF144A","Gene synonym":["hUIP4","KIAA0161","RNF144","UBCE7IP4"],"Ensembl":"ENSG00000151692","Gene description":"Ring finger protein 144A","Uniprot":["P50876"],"Chromosome":"2","Position":"6917412-7068286","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"73.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"174.1","Inhibitory neurons":"99.5","Oligodendrocyte precursor cells":"186.3","Oligodendrocytes":"311.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"6.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"6.1","T-cells":"2.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"26.9","skin cancer":"28.2"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049939"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049939":"AB_2680960"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.00e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.96e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.32e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"}},{"Gene":"RNF144B","Gene synonym":["bA528A10.3","IBRDC2","P53RFP"],"Ensembl":"ENSG00000137393","Gene description":"Ring finger protein 144B","Uniprot":["Q7Z419"],"Chromosome":"6","Position":"18387350-18468870","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"56.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"330.3","Langerhans cells":"300.0","monocytes":"851.4","Schwann cells":"268.1","Suprabasal keratinocytes":"721.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"71.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"18.4","granulocytes":"36.7","monocytes":"71.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"23.6"},"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB046013","HPA054127","HPA072469"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"CAB046013":"AB_11126028","HPA054127":"AB_2682391","HPA072469":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"}},{"Gene":"RNF145","Gene synonym":["FLJ31951"],"Ensembl":"ENSG00000145860","Gene description":"Ring finger protein 145","Uniprot":["Q96MT1"],"Chromosome":"5","Position":"159157409-159210053","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"318.2","Langerhans cells":"339.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"11.4","granulocytes":"16.0","T-cells":"6.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036562"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036562":"AB_10696657"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.64e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"}},{"Gene":"RNF146","Gene synonym":["dactylidin","dJ351K20.1","DKFZp434O1427"],"Ensembl":"ENSG00000118518","Gene description":"Ring finger protein 146","Uniprot":["Q9NTX7"],"Chromosome":"6","Position":"127266682-127288567","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027158","HPA027209"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA027158":"AB_10600772","HPA027209":"AB_10602312"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.26e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"}},{"Gene":"RNF148","Gene synonym":["MGC35222"],"Ensembl":"ENSG00000235631","Gene description":"Ring finger protein 148","Uniprot":["Q8N7C7"],"Chromosome":"7","Position":"122701668-122702922","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"49.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"475.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"9.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045587"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA045587":"AB_10963695"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"RNF149","Gene synonym":["FLJ90504"],"Ensembl":"ENSG00000163162","Gene description":"Ring finger protein 149","Uniprot":["Q8NC42"],"Chromosome":"2","Position":"101271219-101308701","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"365.3","monocytes":"505.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"619.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"619.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011424"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA011424":"AB_1079825"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.04e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.91e-4"}},{"Gene":"RNF150","Gene synonym":["KIAA1214"],"Ensembl":"ENSG00000170153","Gene description":"Ring finger protein 150","Uniprot":["Q9ULK6"],"Chromosome":"4","Position":"140859807-141212877","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"99.7","Cone photoreceptor cells":"94.8","Excitatory neurons":"181.9","Inhibitory neurons":"170.1","Microglial cells":"111.3","Oligodendrocyte precursor cells":"273.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"26.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Liver - Hepatic stellate cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037987"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037987":"AB_10669512"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.41e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"}},{"Gene":"RNF152","Gene synonym":["FLJ39176"],"Ensembl":"ENSG00000176641","Gene description":"Ring finger protein 152","Uniprot":["Q8N8N0"],"Chromosome":"18","Position":"61808067-61894247","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"48.3","choroid plexus":"62.3","kidney":"56.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"84.9","Proximal tubular cells":"141.1","Salivary duct cells":"65.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.13e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.85e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"}},{"Gene":"RNF167","Gene synonym":["DKFZP566H073"],"Ensembl":"ENSG00000108523","Gene description":"Ring finger protein 167","Uniprot":["Q9H6Y7"],"Chromosome":"17","Position":"4940008-4945222","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049810"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Mitotic spindle","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Mitotic spindle","Centriolar satellite"],"Antibody RRID":{"HPA049810":"AB_2680894"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.03e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.47e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"}},{"Gene":"RNF170","Gene synonym":["ADSA","DKFZP564A022","SNAX1"],"Ensembl":"ENSG00000120925","Gene description":"Ring finger protein 170","Uniprot":["Q96K19"],"Chromosome":"8","Position":"42849637-42897290","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050931","HPA054621"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050931":"AB_2681279","HPA054621":"AB_2682545"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"}},{"Gene":"RNF175","Gene synonym":["FLJ34190"],"Ensembl":"ENSG00000145428","Gene description":"Ring finger protein 175","Uniprot":["Q8N4F7"],"Chromosome":"4","Position":"153710160-153760024","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"27.6","choroid plexus":"10.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"84.5","Excitatory neurons":"90.1","Inhibitory neurons":"93.5","Oligodendrocyte precursor cells":"37.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"4.8","skin cancer":"3.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Macrophages","Liver - Neutrophils","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035837"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035837":"AB_10601609"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.11e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"}},{"Gene":"RNF180","Gene synonym":[],"Ensembl":"ENSG00000164197","Gene description":"Ring finger protein 180","Uniprot":["Q86T96"],"Chromosome":"5","Position":"64165843-64372869","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"25.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"89.1","Inhibitory neurons":"148.0","Oligodendrocyte precursor cells":"155.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"7.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006897"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA006897":"AB_1856348"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.81e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"}},{"Gene":"RNF182","Gene synonym":["MGC33993"],"Ensembl":"ENSG00000180537","Gene description":"Ring finger protein 182","Uniprot":["Q8N6D2"],"Chromosome":"6","Position":"13924446-13980310","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"24.7","choroid plexus":"12.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"82.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"28.7"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Endothelial cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012309"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA012309":"AB_1856349"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.66e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"}},{"Gene":"RNF183","Gene synonym":["MGC4734"],"Ensembl":"ENSG00000165188","Gene description":"Ring finger protein 183","Uniprot":["Q96D59"],"Chromosome":"9","Position":"113297093-113303376","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Apoptosis","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"16.4","kidney":"11.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"16.1","Endometrial ciliated cells":"11.1","Enteroendocrine cells":"9.3","Glandular and luminal cells":"17.3","Ionocytes":"32.2","Proximal tubular cells":"25.9","Respiratory ciliated cells":"12.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"7.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"2.1"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Lung - Respiratory ciliated cells","Prostate - Urothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057675"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057675":"AB_2683499"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.95e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.51e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"}},{"Gene":"RNF185","Gene synonym":["FLJ38628"],"Ensembl":"ENSG00000138942","Gene description":"Ring finger protein 185","Uniprot":["Q96GF1"],"Chromosome":"22","Position":"31160182-31207019","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Autophagy","Immunity","Innate immunity","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.82e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"}},{"Gene":"RNF186","Gene synonym":["FLJ20225"],"Ensembl":"ENSG00000178828","Gene description":"Ring finger protein 186","Uniprot":["Q9NXI6"],"Chromosome":"1","Position":"19814029-19815283","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"67.2","intestine":"131.1","pancreas":"43.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Distal enterocytes":"81.4","Enteroendocrine cells":"121.8","Intestinal goblet cells":"55.1","Paneth cells":"139.4","Proximal tubular cells":"91.5","Undifferentiated cells":"85.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"18.5","renal cancer":"12.1","stomach cancer":"7.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"2.4"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034547","HPA035558"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034547":"AB_10670975","HPA035558":"AB_2674678"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"}},{"Gene":"RNF19A","Gene synonym":["DKFZp566B1346","dorfin","RNF19"],"Ensembl":"ENSG00000034677","Gene description":"Ring finger protein 19A, RBR E3 ubiquitin protein ligase","Uniprot":["Q9NV58"],"Chromosome":"8","Position":"100257060-100336218","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"271.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011455","HPA023652"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011455":"AB_2180446","HPA023652":"AB_1847836"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.99e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.28e-5"}},{"Gene":"RNF19B","Gene synonym":["FLJ90005","IBRDC3"],"Ensembl":"ENSG00000116514","Gene description":"Ring finger protein 19B","Uniprot":["Q6ZMZ0"],"Chromosome":"1","Position":"32936445-32964809","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"79.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"67.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"16.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"16.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049587","HPA063640"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA049587":"AB_2680826","HPA063640":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.39e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.41e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.39e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"}},{"Gene":"RNF213","Gene synonym":["ALO17","C17orf27","KIAA1554","KIAA1618","MYMY2","NET57"],"Ensembl":"ENSG00000173821","Gene description":"Ring finger protein 213","Uniprot":["Q63HN8"],"Chromosome":"17","Position":"80260866-80398786","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Immunity","Lipid metabolism","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Multifunctional enzyme","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"331.6","Exocrine glandular cells":"306.0","NK-cells":"347.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003347","HPA026790"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3500","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA003347":"AB_1079204","HPA026790":"AB_10602296"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.65e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"}},{"Gene":"RNF215","Gene synonym":[],"Ensembl":"ENSG00000099999","Gene description":"Ring finger protein 215","Uniprot":["Q9Y6U7"],"Chromosome":"22","Position":"30368811-30421771","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"14.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029427","HPA056498"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Microtubules"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA029427":"AB_2732447","HPA056498":"AB_2683154"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.37e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"}},{"Gene":"RNF217","Gene synonym":["C6orf172","dJ84N20.1","IBRDC1","MGC26996"],"Ensembl":"ENSG00000146373","Gene description":"Ring finger protein 217","Uniprot":["Q8TC41"],"Chromosome":"6","Position":"124962545-125092633","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"42.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"141.3","Oligodendrocytes":"96.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029598"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029598":"AB_10602297"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.60e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.92e-4"}},{"Gene":"RNF220","Gene synonym":["C1orf164","FLJ10597"],"Ensembl":"ENSG00000187147","Gene description":"Ring finger protein 220","Uniprot":["Q5VTB9"],"Chromosome":"1","Position":"44405194-44651724","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"121.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Oligodendrocytes":"2017.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027577","HPA027578"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA027577":"AB_2672339","HPA027578":"AB_10601482"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.35e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.12e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"}},{"Gene":"RNF222","Gene synonym":[],"Ensembl":"ENSG00000189051","Gene description":"Ring finger protein 222","Uniprot":["A6NCQ9"],"Chromosome":"17","Position":"8390704-8397826","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"16.9","skin 1":"6.9","vagina":"5.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7","NK-cells":"1.0","Rod photoreceptor cells":"1.3","Suprabasal keratinocytes":"6.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"1.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"1.2","Gallbladder cancer":"1.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048916"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048916":"AB_2680555"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"}},{"Gene":"RNF223","Gene synonym":[],"Ensembl":"ENSG00000237330","Gene description":"Ring finger protein 223","Uniprot":["E7ERA6"],"Chromosome":"1","Position":"1070967-1074306","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"cervix":"10.6","esophagus":"26.2","vagina":"13.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"27.1","Endometrial ciliated cells":"35.4","Extravillous trophoblasts":"22.7","Gastric mucus-secreting cells":"39.3","Glandular and luminal cells":"33.3","Paneth cells":"19.6","Suprabasal keratinocytes":"27.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.08e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.53e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"}},{"Gene":"RNF24","Gene synonym":["G1L"],"Ensembl":"ENSG00000101236","Gene description":"Ring finger protein 24","Uniprot":["Q9Y225"],"Chromosome":"20","Position":"3927309-4015558","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"51.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"110.9","Inhibitory neurons":"124.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"238.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"238.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011900"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA011900":"AB_10671089"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.81e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.67e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"}},{"Gene":"RNF26","Gene synonym":["MGC2642"],"Ensembl":"ENSG00000173456","Gene description":"Ring finger protein 26","Uniprot":["Q9BY78"],"Chromosome":"11","Position":"119334527-119337309","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"44.9","Extravillous trophoblasts":"69.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027620"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA027620":"AB_1856356"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.45e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.73e-4"}},{"Gene":"RNF43","Gene synonym":["DKFZp781H0392","FLJ20315","URCC"],"Ensembl":"ENSG00000108375","Gene description":"Ring finger protein 43","Uniprot":["Q68DV7"],"Chromosome":"17","Position":"58353676-58417595","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Developmental protein","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"22.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"28.2","Intestinal goblet cells":"23.4","Undifferentiated cells":"33.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"41.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bile duct cancer":"44.6","colorectal cancer":"72.4","Gastric cancer":"38.7"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Lung - Alveolar cells type 2","Skin - Keratinocyte (other)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008079"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008079":"AB_1856371"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.04e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"}},{"Gene":"RNF5","Gene synonym":["G16","NG2","RING5","RMA1"],"Ensembl":"ENSG00000204308","Gene description":"Ring finger protein 5","Uniprot":["Q99942"],"Chromosome":"6","Position":"32178405-32180793","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"274.7","Proximal tubular cells":"324.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034107","HPA065032"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB034107":"AB_2238618","HPA065032":"AB_2685408"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.44e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"}},{"Gene":"RNFT1","Gene synonym":["PTD016"],"Ensembl":"ENSG00000189050","Gene description":"Ring finger protein, transmembrane 1","Uniprot":["Q5M7Z0"],"Chromosome":"17","Position":"59952240-59964761","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"64.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"143.2","Late spermatids":"115.6","Spermatocytes":"218.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013739"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA013739":"AB_1856382"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.57e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.48e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.57e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"}},{"Gene":"RNFT2","Gene synonym":["FLJ14627","TMEM118"],"Ensembl":"ENSG00000135119","Gene description":"Ring finger protein, transmembrane 2","Uniprot":["Q96EX2"],"Chromosome":"12","Position":"116738178-116853631","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"13.8","pituitary gland":"5.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"17.2","Early spermatids":"28.1","Excitatory neurons":"22.4","Inhibitory neurons":"28.0","Late spermatids":"76.8","Oligodendrocyte precursor cells":"17.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064161"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA064161":"AB_2685202"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-4"}},{"Gene":"RO60","Gene synonym":["SSA2","TROVE2"],"Ensembl":"ENSG00000116747","Gene description":"Ro60, Y RNA binding protein","Uniprot":["P10155"],"Chromosome":"1","Position":"193059454-193091777","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Ribonucleoprotein","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"272.4","Late spermatids":"272.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002835"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002835":"AB_1857490"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.31e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"}},{"Gene":"ROBO1","Gene synonym":["DUTT1","FLJ21882","SAX3"],"Ensembl":"ENSG00000169855","Gene description":"Roundabout guidance receptor 1","Uniprot":["Q9Y6N7"],"Chromosome":"3","Position":"78597239-79767998","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Chemotaxis","Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"305.1","Inhibitory neurons":"1478.5","Oligodendrocyte precursor cells":"333.6","Oligodendrocytes":"452.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Heart muscle - Fibroblasts","Prostate - Urothelial cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013524","HPA052968","HPA074461"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB013524":null,"HPA052968":"AB_2682001","HPA074461":"AB_2732256"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.88e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"}},{"Gene":"ROBO2","Gene synonym":["KIAA1568"],"Ensembl":"ENSG00000185008","Gene description":"Roundabout guidance receptor 2","Uniprot":["Q9HCK4"],"Chromosome":"3","Position":"75906695-77649964","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Chemotaxis","Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"16.7","retina":"15.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"24","RNA single cell type specific nTPM":{"Excitatory neurons":"3385.3","Inhibitory neurons":"4585.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Kidney - Podocytes","Lung - Fibroblast_1","Pancreas - Beta cells","Skeletal muscle - Fibroblasts","Skin - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013371","HPA013975"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1900000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Centriolar satellite"],"Antibody RRID":{"HPA013371":"AB_1856391","HPA013975":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-3"}},{"Gene":"ROBO3","Gene synonym":["FLJ21044","HGPPS","HGPS","RBIG1"],"Ensembl":"ENSG00000154134","Gene description":"Roundabout guidance receptor 3","Uniprot":["Q96MS0"],"Chromosome":"11","Position":"124865432-124881471","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Chemotaxis","Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"6.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"31.3","Muller glia cells":"43.5","Thymic epithelial cells":"42.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"2.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071053"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA071053":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-3"}},{"Gene":"ROBO4","Gene synonym":["ECSM4","FLJ20798","MRB"],"Ensembl":"ENSG00000154133","Gene description":"Roundabout guidance receptor 4","Uniprot":["Q8WZ75"],"Chromosome":"11","Position":"124883691-124898500","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Differentiation"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Adipocytes":"174.0","Endothelial cells":"124.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"4.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Lung - Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065212"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"380000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA065212":"AB_2685434"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.85e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.73e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"}},{"Gene":"ROM1","Gene synonym":["ROM","TSPAN23"],"Ensembl":"ENSG00000149489","Gene description":"Retinal outer segment membrane protein 1","Uniprot":["Q03395"],"Chromosome":"11","Position":"62611722-62615116","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"retina":"1186.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"651.2","Cone photoreceptor cells":"727.2","Muller glia cells":"411.6","Rod photoreceptor cells":"2808.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"14.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"2.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"NK-cells":"2.7","T-cells":"1.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028910","HPA073279"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028910":"AB_2672824","HPA073279":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.85e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"}},{"Gene":"ROMO1","Gene synonym":["bA353C18.2","C20orf52","MTGMP"],"Ensembl":"ENSG00000125995","Gene description":"Reactive oxygen species modulator 1","Uniprot":["P60602"],"Chromosome":"20","Position":"35699272-35700984","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Antibiotic","Antimicrobial"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012782"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012782":"AB_1845685"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"}},{"Gene":"ROR1","Gene synonym":["NTRKR1"],"Ensembl":"ENSG00000185483","Gene description":"Receptor tyrosine kinase like orphan receptor 1","Uniprot":["Q01973"],"Chromosome":"1","Position":"63774017-64181498","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Kinase","Receptor","Transferase"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"26.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"108.8","Astrocytes":"78.4","Inhibitory neurons":"68.6","Oligodendrocytes":"103.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7700000","Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"}},{"Gene":"ROR2","Gene synonym":["BDB","BDB1","NTRKR2"],"Ensembl":"ENSG00000169071","Gene description":"Receptor tyrosine kinase like orphan receptor 2","Uniprot":["Q01974"],"Chromosome":"9","Position":"91563091-91950228","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"19.0","Endometrial stromal cells":"18.7","Inhibitory neurons":"18.0","Microglial cells":"15.5","Oligodendrocyte precursor cells":"26.5","Spermatogonia":"14.8","Thymic epithelial cells":"40.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"MAIT T-cell":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"1.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"cerebellum":"7.2","spinal cord":"3.7"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.86e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.28e-8"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"}},{"Gene":"ROS1","Gene synonym":["c-ros-1","MCF3","ROS"],"Ensembl":"ENSG00000047936","Gene description":"ROS proto-oncogene 1, receptor tyrosine kinase","Uniprot":["P08922"],"Chromosome":"6","Position":"117287353-117425942","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"epididymis":"58.6","lung":"31.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Alveolar cells type 2":"141.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"lung cancer":"6.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"2.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"8.8"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049098","HPA072424"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049098":"AB_2680628","HPA072424":"AB_2686519"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"}},{"Gene":"RP1","Gene synonym":["DCDC4A","ORP1"],"Ensembl":"ENSG00000104237","Gene description":"RP1 axonemal microtubule associated","Uniprot":["P56715"],"Chromosome":"8","Position":"54509422-54871720","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"retina":"236.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"165.1","Cone photoreceptor cells":"398.1","Respiratory ciliated cells":"201.9","Rod photoreceptor cells":"972.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Lung - Respiratory ciliated cells","Stomach - Parietal cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"1.3"},"Antibody":["HPA042257"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042257":"AB_10797385"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"}},{"Gene":"RPAP1","Gene synonym":["DKFZP727M111","FLJ12732","KIAA1403","MGC858"],"Ensembl":"ENSG00000103932","Gene description":"RNA polymerase II associated protein 1","Uniprot":["Q9BWH6"],"Chromosome":"15","Position":"41517176-41544269","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription"],"Molecular function":["DNA-binding","Nucleotidyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041739"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA041739":"AB_2677647"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.32e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"}},{"Gene":"RPAP2","Gene synonym":["C1orf82","FLJ13150","Rtr1"],"Ensembl":"ENSG00000122484","Gene description":"RNA polymerase II associated protein 2","Uniprot":["Q8IXW5"],"Chromosome":"1","Position":"92299059-92402056","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"12.6"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046443"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046443":"AB_2679669"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"}},{"Gene":"RPE","Gene synonym":[],"Ensembl":"ENSG00000197713","Gene description":"Ribulose-5-phosphate-3-epimerase","Uniprot":["Q96AT9"],"Chromosome":"2","Position":"210002565-210022260","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036498","HPA036499"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA036498":"AB_2675157","HPA036499":"AB_10670109"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.42e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.00e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"}},{"Gene":"RPGR","Gene synonym":["COD1","CORDX1","CRD","RP15","RP3"],"Ensembl":"ENSG00000156313","Gene description":"Retinitis pigmentosa GTPase regulator","Uniprot":["Q92834"],"Chromosome":"X","Position":"38269163-38327544","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation","Sensory transduction","Vision"],"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Cancer-related genes","Ciliopathy","Cone-rod dystrophy","Deafness","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"148.2","Endothelial cells":"80.2","Rod photoreceptor cells":"80.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"14.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"14.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Stomach - Endothelial cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001593","HPA073455"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA001593":"AB_1079835","HPA073455":"AB_2686603"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"}},{"Gene":"RPGRIP1","Gene synonym":["CORD13","LCA6","RGI1","RPGRIP"],"Ensembl":"ENSG00000092200","Gene description":"RPGR interacting protein 1","Uniprot":["Q96KN7"],"Chromosome":"14","Position":"21280083-21351301","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Ciliopathy","Cone-rod dystrophy","Disease variant","Glaucoma","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"80","RNA tissue specific nTPM":{"retina":"185.3","testis":"59.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"129.2","Early spermatids":"172.5","Late spermatids":"124.6","Rod photoreceptor cells":"130.8","Spermatocytes":"43.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"testis cancer":"1.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"8.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"dendritic cells":"3.3","granulocytes":"8.8","monocytes":"3.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042955","HPA060190"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042955":"AB_2678239","HPA060190":"AB_2684218"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"}},{"Gene":"RPL32","Gene synonym":["L32"],"Ensembl":"ENSG00000144713","Gene description":"Ribosomal protein L32","Uniprot":["P62910"],"Chromosome":"3","Position":"12834485-12841582","Protein class":["Plasma proteins","Predicted intracellular proteins","Ribosomal proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047501","HPA051994"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"45000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA047501":"AB_2680070","HPA051994":"AB_2681686"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"}},{"Gene":"RPL9","Gene synonym":["L9"],"Ensembl":"ENSG00000163682","Gene description":"Ribosomal protein L9","Uniprot":["P32969"],"Chromosome":"4","Position":"39452587-39458931","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Ribosomal proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"2512.5"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003372"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA003372":"AB_1079843"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"}},{"Gene":"RPN1","Gene synonym":["OST1"],"Ensembl":"ENSG00000163902","Gene description":"Ribophorin I","Uniprot":["P04843"],"Chromosome":"3","Position":"128619969-128681075","Protein class":["Cancer-related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"433.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Macrophages","Heart muscle - Macrophages","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009748","HPA026828","HPA051520"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"730000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB009748":"AB_2182230","HPA026828":"AB_10610418","HPA051520":"AB_2681521"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.80e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"}},{"Gene":"RPN2","Gene synonym":["RIBIIR","RPN-II","RPNII","SWP1"],"Ensembl":"ENSG00000118705","Gene description":"Ribophorin II","Uniprot":["P04844"],"Chromosome":"20","Position":"37178410-37241619","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"656.9","Syncytiotrophoblasts":"664.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Macrophages","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008297","CAB019277","HPA025922"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB019277":null,"HPA008297":"AB_1856457","HPA025922":"AB_1856458"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.38e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.44e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.44e-4"}},{"Gene":"RPP30","Gene synonym":["TSG15"],"Ensembl":"ENSG00000148688","Gene description":"Ribonuclease P\/MRP subunit p30","Uniprot":["P78346"],"Chromosome":"10","Position":"90871952-90908553","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["rRNA processing","tRNA processing"],"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037578"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Microtubule ends","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Microtubule ends","Cytosol"],"Antibody RRID":{"HPA037578":"AB_10696939"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.01e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"}},{"Gene":"RPRM","Gene synonym":["FLJ90327","REPRIMO"],"Ensembl":"ENSG00000177519","Gene description":"Reprimo, TP53 dependent G2 arrest mediator homolog","Uniprot":["Q9NS64"],"Chromosome":"2","Position":"153477338-153478762","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"15.5","Endometrial stromal cells":"61.7","Horizontal cells":"13.5","Theca cells":"37.3","Thymic epithelial cells":"14.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"testis cancer":"28.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"}},{"Gene":"RPRML","Gene synonym":["MGC43894"],"Ensembl":"ENSG00000179673","Gene description":"Reprimo like","Uniprot":["Q8N4K4"],"Chromosome":"17","Position":"46978156-46979253","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"12.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"42.0","Excitatory neurons":"17.2","Suprabasal keratinocytes":"8.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.7"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"4.9","basal ganglia":"12.8","cerebral cortex":"9.8","hippocampal formation":"7.1","white matter":"5.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"8.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"90.0"},"Antibody":["HPA062668"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062668":"AB_2684827"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-4"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"RPS10","Gene synonym":["MGC88819","S10"],"Ensembl":"ENSG00000124614","Gene description":"Ribosomal protein S10","Uniprot":["P46783"],"Chromosome":"6","Position":"34417454-34426069","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Ribosomal proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":["Diamond-Blackfan anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Undifferentiated cells":"3553.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047268","HPA048084"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA047268":"AB_2680007","HPA048084":"AB_2680255"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.57e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"}},{"Gene":"RPS13","Gene synonym":["S13"],"Ensembl":"ENSG00000110700","Gene description":"Ribosomal protein S13","Uniprot":["P62277"],"Chromosome":"11","Position":"17074388-17077715","Protein class":["Plasma proteins","Predicted intracellular proteins","Ribosomal proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005985"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA005985":"AB_10960703"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.54e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"}},{"Gene":"RPS19","Gene synonym":["DBA","eS19","LOH19CR1","S19"],"Ensembl":"ENSG00000105372","Gene description":"Ribosomal protein S19","Uniprot":["P39019"],"Chromosome":"19","Position":"41860255-41872925","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Ribosomal proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":["Diamond-Blackfan anemia","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063217"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA063217":"AB_2732699"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.32e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"}},{"Gene":"RPS27L","Gene synonym":[],"Ensembl":"ENSG00000185088","Gene description":"Ribosomal protein S27 like","Uniprot":["Q71UM5"],"Chromosome":"15","Position":"63125872-63158021","Protein class":["Predicted intracellular proteins","Ribosomal proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"1543.8","Proximal tubular cells":"2519.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066851"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA066851":"AB_2685737"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.08e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"}},{"Gene":"RPS5","Gene synonym":["S5"],"Ensembl":"ENSG00000083845","Gene description":"Ribosomal protein S5","Uniprot":["P46782"],"Chromosome":"19","Position":"58386400-58394806","Protein class":["Plasma proteins","Predicted intracellular proteins","Ribosomal proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055878","HPA061979"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"880000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA055878":"AB_2682954","HPA061979":"AB_2684650"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.75e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"}},{"Gene":"RPS6KA3","Gene synonym":["CLS","HU-3","MRX19","RSK2"],"Ensembl":"ENSG00000177189","Gene description":"Ribosomal protein S6 kinase A3","Uniprot":["P51812"],"Chromosome":"X","Position":"20149911-20267519","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Stress response"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003221","CAB003853","CAB013520"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"CAB003853":"AB_562343","CAB013520":"AB_2533378","HPA003221":"AB_1853553"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"}},{"Gene":"RPTOR","Gene synonym":["KIAA1303","KOG1","Mip1","raptor"],"Ensembl":"ENSG00000141564","Gene description":"Regulatory associated protein of MTOR complex 1","Uniprot":["Q8N122"],"Chromosome":"17","Position":"80544819-80966371","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"44.6","Excitatory neurons":"69.0","Inhibitory neurons":"64.9","Oligodendrocyte precursor cells":"48.6","Oligodendrocytes":"62.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013514","HPA064306"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Lysosomes","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles","Lysosomes"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB013514":"AB_2533523","HPA064306":"AB_2685240"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"}},{"Gene":"RRBP1","Gene synonym":["ES\/130","hES"],"Ensembl":"ENSG00000125844","Gene description":"Ribosome binding protein 1","Uniprot":["Q9P2E9"],"Chromosome":"20","Position":"17613678-17682295","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"497.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"730.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"37.8","plasmacytoid DC":"44.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009026","HPA011924"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA009026":"AB_1079852","HPA011924":"AB_1856476"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.41e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.38e-4"}},{"Gene":"RRH","Gene synonym":["peropsin"],"Ensembl":"ENSG00000180245","Gene description":"Retinal pigment epithelium-derived rhodopsin homolog","Uniprot":["O14718"],"Chromosome":"4","Position":"109827972-109849123","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction"],"Molecular function":["G-protein coupled receptor","Photoreceptor protein","Receptor","Retinal protein","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"112","RNA tissue specific nTPM":{"retina":"75.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"19","RNA single cell type specific nTPM":{"Muller glia cells":"202.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"}},{"Gene":"RRM2","Gene synonym":["C2orf48","FLJ25102"],"Ensembl":"ENSG00000171848","Gene description":"Ribonucleotide reductase regulatory subunit M2","Uniprot":["P31350"],"Chromosome":"2","Position":"10120698-10211725","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Deoxyribonucleotide synthesis"],"Molecular function":["Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"44.2","esophagus":"18.4","intestine":"19.7","lymphoid tissue":"58.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"174.6","Extravillous trophoblasts":"290.9","Plasma cells":"282.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Mitotic cells (Colon)","Heart muscle - Mitotic cells (Heart)","Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Testis - Spermatocytes","Thyroid - Mitotic cells (Thyroid)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056994"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA056994":"AB_2683304"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.39e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"}},{"Gene":"RRM2B","Gene synonym":["p53R2"],"Ensembl":"ENSG00000048392","Gene description":"Ribonucleotide reductase regulatory TP53 inducible subunit M2B","Uniprot":["Q7LG56"],"Chromosome":"8","Position":"102204502-102238961","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Deoxyribonucleotide synthesis","DNA damage","DNA repair"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","FDA approved drug targets","Neuropathy","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006854","HPA028812"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB006854":null,"HPA028812":"AB_10602246"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"}},{"Gene":"RRNAD1","Gene synonym":["C1orf66","CGI-41","METTL25B"],"Ensembl":"ENSG00000143303","Gene description":"Ribosomal RNA adenine dimethylase domain containing 1","Uniprot":["Q96FB5"],"Chromosome":"1","Position":"156728442-156736960","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"57.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047426"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA047426":"AB_2680041"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.60e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-3"}},{"Gene":"RSAD2","Gene synonym":["cig5","vig1","Viperin"],"Ensembl":"ENSG00000134321","Gene description":"Radical S-adenosyl methionine domain containing 2","Uniprot":["Q8WXG1"],"Chromosome":"2","Position":"6865557-6898239","Protein class":["Predicted intracellular proteins"],"Biological process":["Antiviral defense","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Lyase"],"Disease involvement":["Atherosclerosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"21.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"32.6","Distal enterocytes":"41.6","Erythroid cells":"32.2","Gastric mucus-secreting cells":"37.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"30.7","eosinophil":"43.3","neutrophil":"25.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"43.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041160","HPA049409"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli fibrillar center","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA041160":"AB_10795489","HPA049409":"AB_2680751"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.60e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"RSPO3","Gene synonym":["FLJ14440","THSD2"],"Ensembl":"ENSG00000146374","Gene description":"R-spondin 3","Uniprot":["Q9BXY4"],"Chromosome":"6","Position":"127118671-127199481","Protein class":["Cancer-related genes","Predicted secreted proteins"],"Biological process":["Sensory transduction","Wnt signaling pathway"],"Molecular function":["Heparin-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"51.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"20.2","Endothelial cells":"18.7","Fibroblasts":"49.6","Inhibitory neurons":"17.3","Leydig cells":"27.9","Smooth muscle cells":"30.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"7.2","Rhabdoid":"19.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Liver - Hepatic stellate cells","Lung - Fibroblast_2","Pancreas - Fibroblasts","Prostate - Smooth muscle cells","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"21.2"},"Antibody":["HPA029957"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029957":"AB_10602087"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-3"}},{"Gene":"RSPRY1","Gene synonym":["KIAA1972"],"Ensembl":"ENSG00000159579","Gene description":"Ring finger and SPRY domain containing 1","Uniprot":["Q96DX4"],"Chromosome":"16","Position":"57186137-57240469","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Dwarfism","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003729"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003729":"AB_10964215"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.21e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-3"}},{"Gene":"RTBDN","Gene synonym":["FLJ36353"],"Ensembl":"ENSG00000132026","Gene description":"Retbindin","Uniprot":["Q9BSG5"],"Chromosome":"19","Position":"12825478-12835428","Protein class":["Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"retina":"288.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"947.8","Rod photoreceptor cells":"453.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"13.6"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052511"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA052511":"AB_2797243"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"}},{"Gene":"RTEL1","Gene synonym":["bK3184A7.3","C20orf41","DKFZP434C013","KIAA1088","NHL","RTEL"],"Ensembl":"ENSG00000258366","Gene description":"Regulator of telomere elongation helicase 1","Uniprot":["Q9NZ71"],"Chromosome":"20","Position":"63657810-63696253","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Disease variant","Dyskeratosis congenita"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"3.4","Gastric mucus-secreting cells":"3.6","Plasma cells":"3.3","Thymic epithelial cells":"1.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020622","HPA078328"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Nucleoplasm","Nuclear membrane"],"Antibody RRID":{"HPA020622":"AB_2732425","HPA078328":"AB_2732380"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"}},{"Gene":"RTF2","Gene synonym":["C20orf43","CDAO5","HSPC164","RTFDC1"],"Ensembl":"ENSG00000022277","Gene description":"Replication termination factor 2","Uniprot":["Q9BY42"],"Chromosome":"20","Position":"56468585-56519449","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053986"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA053986":"AB_2682333"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.35e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.31e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-3"}},{"Gene":"RTKN2","Gene synonym":["bA531F24.1","Em:AC024597.2","FLJ39352","PLEKHK1"],"Ensembl":"ENSG00000182010","Gene description":"Rhotekin 2","Uniprot":["Q8IZC4"],"Chromosome":"10","Position":"62183035-62268844","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"lung":"77.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"107.1","Early spermatids":"456.7","Late spermatids":"168.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"1.6"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"T-reg":"16.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"72","RNA blood lineage specific nTPM":{"T-cells":"16.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Lung - Alveolar cells type 1","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037946","HPA038446"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA037946":"AB_10795398","HPA038446":"AB_10796218"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"}},{"Gene":"RTL1","Gene synonym":["HUR1","Mar1","MART1","PEG11","SIRH2"],"Ensembl":"ENSG00000254656","Gene description":"Retrotransposon Gag like 1","Uniprot":["A6NKG5"],"Chromosome":"14","Position":"100879753-100903722","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"1.6","brain":"7.7","placenta":"2.9"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"1.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"43.2"},"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066979","HPA077601"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA066979":"AB_2685759","HPA077601":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"RTN1","Gene synonym":["NSP"],"Ensembl":"ENSG00000139970","Gene description":"Reticulon 1","Uniprot":["Q16799"],"Chromosome":"14","Position":"59595976-59870776","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"160.6","pituitary gland":"60.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"488.7","Horizontal cells":"183.9","Inhibitory neurons":"384.7","Oligodendrocyte precursor cells":"180.0","Oligodendrocytes":"233.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"19.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"2.9","intermediate monocyte":"3.1","myeloid DC":"5.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"dendritic cells":"5.4","monocytes":"3.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"89.6"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002745","HPA040945","HPA044249"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB002745":null,"HPA040945":"AB_2677217","HPA044249":"AB_2678874"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.69e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"}},{"Gene":"RTN2","Gene synonym":["NSP2","NSPL1","SPG12"],"Ensembl":"ENSG00000125744","Gene description":"Reticulon 2","Uniprot":["O75298"],"Chromosome":"19","Position":"45485294-45497055","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"skeletal muscle":"509.8","tongue":"207.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"135.6","Extravillous trophoblasts":"171.8","Skeletal myocytes":"115.8","Syncytiotrophoblasts":"111.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"6.2","eosinophil":"2.6","plasmacytoid DC":"1.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"1.6","granulocytes":"6.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034948","HPA078531"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA034948":"AB_2674375","HPA078531":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"}},{"Gene":"RTN3","Gene synonym":["ASYIP","HAP","NSPL2","NSPLII","RTN3-A1"],"Ensembl":"ENSG00000133318","Gene description":"Reticulon 3","Uniprot":["O95197"],"Chromosome":"11","Position":"63681446-63759891","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","ER-Golgi transport","Host-virus interaction","Stress response","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"514.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1074.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"1074.7","monocytes":"400.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Kidney - Fibroblasts","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015649","HPA015650"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA015649":"AB_1856498","HPA015650":"AB_1856499"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.30e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"}},{"Gene":"RTN4","Gene synonym":["ASY","KIAA0886","NOGO","NSP-CL"],"Ensembl":"ENSG00000115310","Gene description":"Reticulon 4","Uniprot":["Q9NQC3"],"Chromosome":"2","Position":"54972187-55112621","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Neurogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Muller glia cells":"3296.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"95.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005388","HPA023977"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3400000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB005388":"AB_2285559","HPA023977":"AB_2671391"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.00e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"}},{"Gene":"RTN4R","Gene synonym":["NOGOR"],"Ensembl":"ENSG00000040608","Gene description":"Reticulon 4 receptor","Uniprot":["Q9BZR6"],"Chromosome":"22","Position":"20241415-20283246","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Schizophrenia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"24.3","liver":"12.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"13.0","Excitatory neurons":"14.0","Muller glia cells":"11.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"10","RNA brain regional specific nTPM":{"amygdala":"8.0","basal ganglia":"20.0","cerebellum":"20.9","cerebral cortex":"24.3","hippocampal formation":"12.7"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"10.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"10.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012443"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1900000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Focal adhesion sites"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB012443":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.73e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"}},{"Gene":"RTN4RL1","Gene synonym":["DKFZp547J144","NgR3","NGRH2"],"Ensembl":"ENSG00000185924","Gene description":"Reticulon 4 receptor like 1","Uniprot":["Q86UN2"],"Chromosome":"17","Position":"1934677-2025334","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"12.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"17.5","Cone photoreceptor cells":"27.6","Excitatory neurons":"42.9","Horizontal cells":"19.2","Inhibitory neurons":"18.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"12.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"8.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044428"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Actin filaments","Midbody"],"Secretome location":"Intracellular and membrane","CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"35000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Nucleoplasm","Plasma membrane","Midbody"],"Antibody RRID":{"HPA044428":"AB_10963229"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"}},{"Gene":"RTP1","Gene synonym":["MGC35450","Z3CXXC1"],"Ensembl":"ENSG00000175077","Gene description":"Receptor transporter protein 1","Uniprot":["P59025"],"Chromosome":"3","Position":"187197486-187201462","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"2.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"3.5","Late spermatids":"2.1","Spermatocytes":"3.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"26","RNA cell line specific nTPM":{"Rhabdoid":"1.3","testis cancer":"4.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"RTP2","Gene synonym":["MGC78665","Z3CXXC2"],"Ensembl":"ENSG00000198471","Gene description":"Receptor transporter protein 2","Uniprot":["Q5QGT7"],"Chromosome":"3","Position":"187698259-187702557","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"skeletal muscle":"2.0","testis":"1.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"17.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"RTP3","Gene synonym":["LTM1","TMEM7","Z3CXXC3"],"Ensembl":"ENSG00000163825","Gene description":"Receptor transporter protein 3","Uniprot":["Q9BQQ7"],"Chromosome":"3","Position":"46497976-46500950","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"130","RNA tissue specific nTPM":{"liver":"119.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Hepatocytes":"121.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"22.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"2.7","head and neck cancer":"3.2"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075932"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA075932":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.11e-6"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"RTP4","Gene synonym":["IFRG28","Z3CXXC4"],"Ensembl":"ENSG00000136514","Gene description":"Receptor transporter protein 4","Uniprot":["Q96DX8"],"Chromosome":"3","Position":"187368385-187372076","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"44.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"14.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064887","HPA071189"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA064887":"AB_2685383","HPA071189":"AB_2686357"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.83e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.35e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.45e-4"}},{"Gene":"RTP5","Gene synonym":["C2orf85","CXXC11","FLJ33590","Z3CXXC5"],"Ensembl":"ENSG00000188011","Gene description":"Receptor transporter protein 5 (putative)","Uniprot":["Q14D33"],"Chromosome":"2","Position":"241869600-241873823","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"brain":"32.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"4.0","Late spermatids":"6.1","Oligodendrocyte precursor cells":"16.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"glioma":"1.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050902"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050902":"AB_2681268"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"}},{"Gene":"RTTN","Gene synonym":["DKFZP434G145"],"Ensembl":"ENSG00000176225","Gene description":"Rotatin","Uniprot":["Q86VV8"],"Chromosome":"18","Position":"70003031-70205726","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"67.5","Oligodendrocyte precursor cells":"46.7","Oligodendrocytes":"104.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041343","HPA041967","HPA075089"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA041343":"AB_10794409","HPA041967":"AB_10796790","HPA075089":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"}},{"Gene":"RUNDC1","Gene synonym":["DKFZp761H0421"],"Ensembl":"ENSG00000198863","Gene description":"RUN domain containing 1","Uniprot":["Q96C34"],"Chromosome":"17","Position":"42980565-42993690","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023726"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA023726":"AB_2184078"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.93e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-3"}},{"Gene":"RUSC1","Gene synonym":["NESCA"],"Ensembl":"ENSG00000160753","Gene description":"RUN and SH3 domain containing 1","Uniprot":["Q9BVN2"],"Chromosome":"1","Position":"155320894-155331114","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028510","HPA029922","HPA029923"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028510":"AB_10599847","HPA029922":"AB_10611390","HPA029923":"AB_10602288"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.78e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.65e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"}},{"Gene":"RUSC2","Gene synonym":["KIAA0375"],"Ensembl":"ENSG00000198853","Gene description":"RUN and SH3 domain containing 2","Uniprot":["Q8N2Y8"],"Chromosome":"9","Position":"35490111-35561898","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"32.6","Excitatory neurons":"60.6","Inhibitory neurons":"62.1","Microglial cells":"42.0","Oligodendrocyte precursor cells":"50.1","Oligodendrocytes":"36.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"3.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"3.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021297"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021297":"AB_1856510"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-3"}},{"Gene":"RUSF1","Gene synonym":["C16orf58","FLJ13868"],"Ensembl":"ENSG00000140688","Gene description":"RUS family member 1","Uniprot":["Q96GQ5"],"Chromosome":"16","Position":"31489471-31509309","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024406"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Golgi apparatus","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoli","Golgi apparatus","Vesicles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA024406":"AB_1845580"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"}},{"Gene":"RWDD3","Gene synonym":["DKFZP566K023","RSUME"],"Ensembl":"ENSG00000122481","Gene description":"RWD domain containing 3","Uniprot":["Q9Y3V2"],"Chromosome":"1","Position":"95234210-95247225","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"15.2","Basal squamous epithelial cells":"15.5","Erythroid cells":"14.9","Oligodendrocyte precursor cells":"14.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.46e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.06e-4"}},{"Gene":"RXFP1","Gene synonym":["LGR7","RXFPR1"],"Ensembl":"ENSG00000171509","Gene description":"Relaxin family peptide receptor 1","Uniprot":["Q9HBX9"],"Chromosome":"4","Position":"158315311-158653372","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"5.3","brain":"7.6","endometrium 1":"6.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"57.1","Excitatory neurons":"165.1","Glandular and luminal cells":"164.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"endometrial cancer":"3.9"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"4.6","basal ganglia":"5.3","cerebral cortex":"7.6","hippocampal formation":"4.6","white matter":"3.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"33.3","Uterine cancer":"13.6"},"RNA tissue cell type enrichment":["Kidney - Podocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"cerebral cortex":"11.8","hippocampal formation":"7.8"},"Antibody":["HPA027067"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027067":"AB_10602127"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-6"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-3"}},{"Gene":"RXFP2","Gene synonym":["GPR106","GREAT","INSL3R","LGR8","RXFPR2"],"Ensembl":"ENSG00000133105","Gene description":"Relaxin family peptide receptor 2","Uniprot":["Q8WXD0"],"Chromosome":"13","Position":"31739526-31803389","Protein class":["Disease related genes","G-protein coupled receptors","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Early spermatids":"10.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"classical monocyte":"1.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"monocytes":"1.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.0","Sarcoma":"1.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"10","RNA pig brain regional specific nTPM":{"basal ganglia":"2.6"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"RXFP3","Gene synonym":["GPCR135","RLN3R1","RXFPR3","SALPR"],"Ensembl":"ENSG00000182631","Gene description":"Relaxin family peptide receptor 3","Uniprot":["Q9NSD7"],"Chromosome":"5","Position":"33936386-33938918","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027833"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027833":"AB_1849247"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"RXFP4","Gene synonym":["GPCR142","GPR100","RLN3R2","RXFPR4"],"Ensembl":"ENSG00000173080","Gene description":"Relaxin family peptide\/INSL5 receptor 4","Uniprot":["Q8TDU9"],"Chromosome":"1","Position":"155941638-155943087","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.8","intestine":"1.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Enteroendocrine cells":"52.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"2.4"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"1.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"3.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"}},{"Gene":"RYK","Gene synonym":["D3S3195","JTK5","JTK5A","RYK1"],"Ensembl":"ENSG00000163785","Gene description":"Receptor like tyrosine kinase","Uniprot":["P34925"],"Chromosome":"3","Position":"134065303-134250859","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034117","HPA045503","HPA075430"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB034117":"AB_2183048","HPA045503":"AB_2679353","HPA075430":"AB_2732293"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.60e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"}},{"Gene":"RYR1","Gene synonym":["CCO","MHS","MHS1","PPP1R137","RYR"],"Ensembl":"ENSG00000196218","Gene description":"Ryanodine receptor 1","Uniprot":["P21817"],"Chromosome":"19","Position":"38433691-38587564","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Developmental protein","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skeletal muscle":"1618.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Skeletal myocytes":"452.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"intermediate monocyte":"1.8","myeloid DC":"2.9","non-classical monocyte":"3.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"2.9","monocytes":"3.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"30.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056416"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"46000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA056416":"AB_2683121"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"RYR2","Gene synonym":["ARVC2","ARVD2","VTSIP"],"Ensembl":"ENSG00000198626","Gene description":"Ryanodine receptor 2","Uniprot":["Q92736"],"Chromosome":"1","Position":"237042184-237833988","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Developmental protein","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Cardiomyopathy","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"heart muscle":"132.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Cardiomyocytes":"2776.9","Excitatory neurons":"1300.5","Inhibitory neurons":"774.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"4.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020028"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA020028":"AB_1856528"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"}},{"Gene":"RYR3","Gene synonym":[],"Ensembl":"ENSG00000198838","Gene description":"Ryanodine receptor 3","Uniprot":["Q15413"],"Chromosome":"15","Position":"33310962-33866121","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"43.7","choroid plexus":"33.3","skeletal muscle":"24.2","tongue":"44.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"764.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"basophil":"1.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"granulocytes":"1.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"2.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"23.4"},"Antibody":["HPA062004"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA062004":"AB_2797267"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"}},{"Gene":"S1PR1","Gene synonym":["CD363","D1S3362","edg-1","EDG1"],"Ensembl":"ENSG00000170989","Gene description":"Sphingosine-1-phosphate receptor 1","Uniprot":["P21453"],"Chromosome":"1","Position":"101236865-101243713","Protein class":["Cancer-related genes","CD markers","FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis","Chemotaxis"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"261.4","Endothelial cells":"153.5","NK-cells":"58.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1248.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"21.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Lung - Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010104","HPA075568"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB010104":"AB_2238920","HPA075568":"AB_2686758"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.78e-4"}},{"Gene":"S1PR2","Gene synonym":["AGR16","DFNB68","EDG5","Gpcr13","H218"],"Ensembl":"ENSG00000267534","Gene description":"Sphingosine-1-phosphate receptor 2","Uniprot":["O95136"],"Chromosome":"19","Position":"10221433-10231331","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"90.2","Early spermatids":"67.9","Late spermatids":"201.9","Syncytiotrophoblasts":"62.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"45.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"45.0","T-cells":"12.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"24.2"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Prostate - Fibroblasts","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014255","HPA014307"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear speckles","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA014255":null,"HPA014307":"AB_1847989"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.36e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"}},{"Gene":"S1PR3","Gene synonym":["EDG-3","EDG3"],"Ensembl":"ENSG00000213694","Gene description":"Sphingosine-1-phosphate receptor 3","Uniprot":["Q99500","Q6ZRZ4"],"Chromosome":"9","Position":"88990863-89005155","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"67.2","Fibroblasts":"24.4","Sertoli cells":"41.5","Smooth muscle cells":"37.4","Theca cells":"49.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"18","RNA blood cell specific nTPM":{"classical monocyte":"7.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"monocytes":"7.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.91e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.30e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.91e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"S1PR4","Gene synonym":["EDG6"],"Ensembl":"ENSG00000125910","Gene description":"Sphingosine-1-phosphate receptor 4","Uniprot":["O95977"],"Chromosome":"19","Position":"3172346-3180332","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"19.6","lymphoid tissue":"61.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"64.7","dendritic cells":"40.5","Hofbauer cells":"37.9","Kupffer cells":"35.7","monocytes":"72.1","NK-cells":"119.6","T-cells":"75.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"2.4"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"Leukemia":"45.1","lymphoma":"36.4","Myeloma":"25.5"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Prostate - T-cells","Stomach - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060601","HPA067232"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA060601":"AB_2797261","HPA067232":"AB_2797271"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.45e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-3"}},{"Gene":"S1PR5","Gene synonym":["Edg-8","EDG8"],"Ensembl":"ENSG00000180739","Gene description":"Sphingosine-1-phosphate receptor 5","Uniprot":["Q9H228"],"Chromosome":"19","Position":"10512742-10517931","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"19.7","brain":"60.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"NK-cells":"173.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"cervical cancer":"11.7","head and neck cancer":"8.0","lung cancer":"3.7","urothelial cancer":"6.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"gdT-cell":"299.4","MAIT T-cell":"184.9","memory CD8 T-cell":"144.9","naive CD8 T-cell":"109.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"T-cells":"299.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"16.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Liver - NK-cells (Liver)","Lung - NK-cells (Lung)","Skin - Keratinocyte (other)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029683"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029683":"AB_10603237"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.71e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"}},{"Gene":"SAA2-SAA4","Gene synonym":[],"Ensembl":"ENSG00000255071","Gene description":"SAA2-SAA4 readthrough","Uniprot":[],"Chromosome":"11","Position":"18231423-18248635","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"127.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"3.0","Ionocytes":"1.5","Respiratory ciliated cells":"2.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"liver cancer":"39.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"14.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060139"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060139":"AB_2684210"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.56e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.92e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"}},{"Gene":"SACM1L","Gene synonym":["KIAA0851","SAC1"],"Ensembl":"ENSG00000211456","Gene description":"SAC1 like phosphatidylinositide phosphatase","Uniprot":["Q9NTJ5"],"Chromosome":"3","Position":"45689056-45745409","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039573","HPA069869"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"82000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA039573":"AB_10674983","HPA069869":"AB_2686216"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.47e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"}},{"Gene":"SAMD4A","Gene synonym":["DKFZP434H0350","hSmaug1","KIAA1053","SAMD4","Smaug","SMG","SMGA"],"Ensembl":"ENSG00000020577","Gene description":"Sterile alpha motif domain containing 4A","Uniprot":["Q9UPU9"],"Chromosome":"14","Position":"54566117-54793315","Protein class":["Predicted intracellular proteins"],"Biological process":["Translation regulation"],"Molecular function":["Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"94.3","testis":"107.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"804.7","Late spermatids":"2426.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"1.2","non-classical monocyte":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043061","HPA065309"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA043061":"AB_2678299","HPA065309":"AB_2685462"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"}},{"Gene":"SAMD5","Gene synonym":["dJ875H10.1"],"Ensembl":"ENSG00000203727","Gene description":"Sterile alpha motif domain containing 5","Uniprot":["Q5TGI4"],"Chromosome":"6","Position":"147508690-147737547","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"91.5","Inhibitory neurons":"271.5","Squamous epithelial cells":"49.9","Suprabasal keratinocytes":"62.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Skeletal muscle - Fibroblasts","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067811"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA067811":"AB_2685901"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.23e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"}},{"Gene":"SAMD8","Gene synonym":["FLJ25082","SMSr"],"Ensembl":"ENSG00000156671","Gene description":"Sterile alpha motif domain containing 8","Uniprot":["Q96LT4"],"Chromosome":"10","Position":"75099586-75182123","Protein class":["Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"19.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044402"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA044402":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-3"}},{"Gene":"SARAF","Gene synonym":["MGC8721","TMEM66"],"Ensembl":"ENSG00000133872","Gene description":"Store-operated calcium entry associated regulatory factor","Uniprot":["Q96BY9"],"Chromosome":"8","Position":"30063003-30083208","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040400"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"41000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Rods & Rings"],"Antibody RRID":{"HPA040400":"AB_2676962"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.28e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"}},{"Gene":"SARS1","Gene synonym":["SARS","SERS"],"Ensembl":"ENSG00000031698","Gene description":"Seryl-tRNA synthetase 1","Uniprot":["P49591"],"Chromosome":"1","Position":"109213918-109238182","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis","Transcription","Transcription regulation"],"Molecular function":["Aminoacyl-tRNA synthetase","DNA-binding","Ligase"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016939","HPA064668"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"330000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA016939":"AB_1856585","HPA064668":"AB_2685316"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.47e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.75e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.13e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"}},{"Gene":"SAT1","Gene synonym":["SAT","SSAT"],"Ensembl":"ENSG00000130066","Gene description":"Spermidine\/spermine N1-acetyltransferase 1","Uniprot":["P21673"],"Chromosome":"X","Position":"23783173-23786226","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"8410.7","Ionocytes":"7943.6","Langerhans cells":"15833.5","monocytes":"8173.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"3422.0","non-classical monocyte":"2519.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"3422.0","monocytes":"2519.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB047343","HPA055312","CAB069914"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB047343":null,"CAB069914":"AB_830224","HPA055312":"AB_2682781"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.87e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"}},{"Gene":"SAYSD1","Gene synonym":["C6orf64","FLJ11101"],"Ensembl":"ENSG00000112167","Gene description":"SAYSVFN motif domain containing 1","Uniprot":["Q9NPB0"],"Chromosome":"6","Position":"39104063-39115186","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"55.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"159.8","Spermatocytes":"193.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007959"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA007959":"AB_1078359"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"}},{"Gene":"SBK1","Gene synonym":["Sbk"],"Ensembl":"ENSG00000188322","Gene description":"SH3 domain binding kinase 1","Uniprot":["Q52WX2"],"Chromosome":"16","Position":"28259246-28323849","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"26.8","skeletal muscle":"44.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"27.6","Excitatory neurons":"37.7","Granulosa cells":"26.4","Horizontal cells":"29.5","NK-cells":"25.8","Skeletal myocytes":"22.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"28.8"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebellum":"275.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.88e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-3"}},{"Gene":"SBK2","Gene synonym":["SGK069"],"Ensembl":"ENSG00000187550","Gene description":"SH3 domain binding kinase family member 2","Uniprot":["P0C263"],"Chromosome":"19","Position":"55528611-55537133","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"heart muscle":"87.2","tongue":"28.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"23.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"1.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"11.4"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Cardiomyocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030631"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030631":"AB_10602088"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SBK3","Gene synonym":["SgK110"],"Ensembl":"ENSG00000231274","Gene description":"SH3 domain binding kinase family member 3","Uniprot":["P0C264"],"Chromosome":"19","Position":"55540656-55545543","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"32.5","tongue":"15.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"3.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078322"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA078322":"AB_2732379"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"SC5D","Gene synonym":["SC5DL"],"Ensembl":"ENSG00000109929","Gene description":"Sterol-C5-desaturase","Uniprot":["O75845"],"Chromosome":"11","Position":"121292681-121313410","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"393.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"300.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Liver - Hepatocytes","Lung - Alveolar cells type 2","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066283","HPA070248"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Nucleoplasm","Endoplasmic reticulum"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA066283":"AB_2685648","HPA070248":"AB_2686240"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.30e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.98e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.07e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"}},{"Gene":"SCAF11","Gene synonym":["CASP11","SFRS2IP","SIP1","SRRP129","SRSF2IP"],"Ensembl":"ENSG00000139218","Gene description":"SR-related CTD associated factor 11","Uniprot":["Q99590"],"Chromosome":"12","Position":"45919131-45992120","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038862","HPA045456","HPA046345"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nucleoli","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Nuclear bodies"],"Antibody RRID":{"HPA038862":"AB_10672830","HPA045456":"AB_2679331","HPA046345":"AB_2679630"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"}},{"Gene":"SCAF8","Gene synonym":["KIAA1116","RBM16"],"Ensembl":"ENSG00000213079","Gene description":"SR-related CTD associated factor 8","Uniprot":["Q9UPN6"],"Chromosome":"6","Position":"154733378-154834244","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"103.9","Inhibitory neurons":"111.5","Microglial cells":"116.8","Oligodendrocyte precursor cells":"116.0","Oligodendrocytes":"137.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035601","HPA035602"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA035601":"AB_2674698","HPA035602":"AB_10673220"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.61e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"}},{"Gene":"SCAI","Gene synonym":["C9orf126","FLJ36664","NET40"],"Ensembl":"ENSG00000173611","Gene description":"Suppressor of cancer cell invasion","Uniprot":["Q8N9R8"],"Chromosome":"9","Position":"124942608-125143528","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Repressor","Signal transduction inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"11.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"322.9","Inhibitory neurons":"167.3","Rod photoreceptor cells":"140.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020632"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA020632":"AB_1845804"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-3"}},{"Gene":"SCAMP1","Gene synonym":["SCAMP37"],"Ensembl":"ENSG00000085365","Gene description":"Secretory carrier membrane protein 1","Uniprot":["O15126"],"Chromosome":"5","Position":"78360611-78480739","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"191.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044753","CAB079009"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"CAB079009":null,"HPA044753":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"}},{"Gene":"SCAMP2","Gene synonym":[],"Ensembl":"ENSG00000140497","Gene description":"Secretory carrier membrane protein 2","Uniprot":["O15127"],"Chromosome":"15","Position":"74843730-74873365","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Colon - Macrophages","Heart muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014699","HPA019194"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"71000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA014699":"AB_1856605","HPA019194":"AB_1856604"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"}},{"Gene":"SCAMP3","Gene synonym":["C1orf3"],"Ensembl":"ENSG00000116521","Gene description":"Secretory carrier membrane protein 3","Uniprot":["O14828"],"Chromosome":"1","Position":"155255979-155262430","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071167"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"75000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA071167":"AB_2686352"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.92e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"}},{"Gene":"SCAMP4","Gene synonym":["FLJ33847"],"Ensembl":"ENSG00000227500","Gene description":"Secretory carrier membrane protein 4","Uniprot":["Q969E2"],"Chromosome":"19","Position":"1905372-1926013","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043284"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Lipid droplets","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Lipid droplets","Plasma membrane"],"Antibody RRID":{"HPA043284":"AB_10806501"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.40e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.92e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.56e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"}},{"Gene":"SCAMP5","Gene synonym":["MGC24969"],"Ensembl":"ENSG00000198794","Gene description":"Secretory carrier membrane protein 5","Uniprot":["Q8TAC9"],"Chromosome":"15","Position":"74957219-75021495","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Exocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"179.9","parathyroid gland":"103.1","retina":"283.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"113.6","Cone photoreceptor cells":"170.6","dendritic cells":"97.9","Excitatory neurons":"74.0","Horizontal cells":"68.6","Inhibitory neurons":"97.0","Rod photoreceptor cells":"158.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"33","RNA blood cell specific nTPM":{"plasmacytoid DC":"27.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"dendritic cells":"27.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"74.6"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046645"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046645":"AB_2679734"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.67e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.34e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"}},{"Gene":"SCAP","Gene synonym":["KIAA0199"],"Ensembl":"ENSG00000114650","Gene description":"SREBF chaperone","Uniprot":["Q12770"],"Chromosome":"3","Position":"47413681-47477126","Protein class":["Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"135.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"102.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004713"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004713":"AB_1079868"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.33e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-3"}},{"Gene":"SCARA3","Gene synonym":["APC7","CSR","CSR1","MSLR1","MSRL1"],"Ensembl":"ENSG00000168077","Gene description":"Scavenger receptor class A member 3","Uniprot":["Q6AZY7"],"Chromosome":"8","Position":"27633868-27676776","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"136.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"231.2","Basal prostatic cells":"71.1","Collecting duct cells":"66.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"80.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Heart muscle - Fibroblasts","Lung - Fibroblast_2","Prostate - Smooth muscle cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029861","HPA047386"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA029861":"AB_2673225","HPA047386":"AB_2680024"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-3"}},{"Gene":"SCARA5","Gene synonym":["FLJ23907","MGC45780","NET33"],"Ensembl":"ENSG00000168079","Gene description":"Scavenger receptor class A member 5","Uniprot":["Q6ZMJ2"],"Chromosome":"8","Position":"27869883-27992673","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Iron transport","Transport"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"90.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Fibroblasts":"188.7","Leydig cells":"137.3","Theca cells":"50.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"121","RNA blood cell specific nTPM":{"plasmacytoid DC":"21.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"211","RNA blood lineage specific nTPM":{"dendritic cells":"21.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Rhabdoid":"12.0","Sarcoma":"17.0","skin cancer":"4.5"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Lung - Fibroblast_2","Pancreas - Fibroblasts","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"spinal cord":"19.5"},"Antibody":["HPA024661"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024661":"AB_1853902"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"}},{"Gene":"SCARB1","Gene synonym":["CD36L1","CLA-1","CLA1","SR-BI","SRB1"],"Ensembl":"ENSG00000073060","Gene description":"Scavenger receptor class B member 1","Uniprot":["Q8WTV0"],"Chromosome":"12","Position":"124776856-124882668","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adrenal gland":"995.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"146.9","Granulosa cells":"129.4","Hepatocytes":"150.4","Kupffer cells":"143.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"6.2","myeloid DC":"8.9","plasmacytoid DC":"21.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"21.0","monocytes":"6.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066285","CAB070124","HPA072449"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Lysosomes","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Vesicles"],"Subcellular additional location":["Lysosomes","Rods & Rings"],"Antibody RRID":{"CAB070124":"AB_10107658","HPA066285":"AB_2685649","HPA072449":"AB_2732201"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.02e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"}},{"Gene":"SCARB2","Gene synonym":["CD36L2","HLGP85","LIMP-2","LIMPII","SR-BII"],"Ensembl":"ENSG00000138760","Gene description":"Scavenger receptor class B member 2","Uniprot":["Q14108"],"Chromosome":"4","Position":"76158737-76234536","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"12.5","classical monocyte":"14.1","intermediate monocyte":"26.0","myeloid DC":"8.2","non-classical monocyte":"24.9","plasmacytoid DC":"28.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"28.9","granulocytes":"12.5","monocytes":"26.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Liver - Hepatocytes","Lung - Fibroblast_1","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015415","HPA018014"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9200","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB015415":"AB_831511","HPA018014":"AB_1852881"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.82e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"}},{"Gene":"SCARF2","Gene synonym":["HUMZD58C02","SREC-II","SREC2"],"Ensembl":"ENSG00000244486","Gene description":"Scavenger receptor class F member 2","Uniprot":["Q96GP6"],"Chromosome":"22","Position":"20424584-20437826","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"16.5","Fibroblasts":"24.9","Peritubular cells":"16.6","Respiratory ciliated cells":"13.7","Smooth muscle cells":"23.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035079"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"580000","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA035079":"AB_10670287"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.28e-4"}},{"Gene":"SCART1","Gene synonym":["CD163c-alpha"],"Ensembl":"ENSG00000214279","Gene description":"Scavenger receptor family member expressed on T cells 1","Uniprot":["Q4G0T1"],"Chromosome":"10","Position":"133453928-133523558","Protein class":["Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"4.7","Horizontal cells":"3.2","Rod photoreceptor cells":"5.8","Skeletal myocytes":"3.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043101"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043101":"AB_10797026"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"}},{"Gene":"SCCPDH","Gene synonym":["CGI-49","NET11"],"Ensembl":"ENSG00000143653","Gene description":"Saccharopine dehydrogenase (putative)","Uniprot":["Q8NBX0"],"Chromosome":"1","Position":"246724409-246768137","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"159.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1571.1","Late spermatids":"326.2","Spermatocytes":"705.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"20","RNA blood cell specific nTPM":{"basophil":"872.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"granulocytes":"872.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050775","HPA076030"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA050775":"AB_2681231","HPA076030":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"}},{"Gene":"SCD","Gene synonym":["FADS5","SCDOS"],"Ensembl":"ENSG00000099194","Gene description":"Stearoyl-CoA desaturase","Uniprot":["O00767"],"Chromosome":"10","Position":"100347233-100364826","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"1233.7","brain":"839.9","liver":"583.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"486.7","Hepatocytes":"753.3","Kupffer cells":"960.5","Oligodendrocytes":"426.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012107","HPA063921"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA012107":"AB_1856610","HPA063921":"AB_2685154"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.56e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.79e-5"}},{"Gene":"SCD5","Gene synonym":["ACOD4","FADS4","FLJ21032","HSCD5","SCD4"],"Ensembl":"ENSG00000145284","Gene description":"Stearoyl-CoA desaturase 5","Uniprot":["Q86SK9"],"Chromosome":"4","Position":"82629539-82798796","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"156.7","brain":"353.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"240.7","Oligodendrocyte precursor cells":"854.9","Oligodendrocytes":"484.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"152.4","thyroid cancer":"38.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Prostate - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042380"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042380":"AB_10794797"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.32e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"}},{"Gene":"SCIMP","Gene synonym":["C17orf87","DTFT5783","FLJ32580","MGC163426","MGC163428","UNQ5783"],"Ensembl":"ENSG00000161929","Gene description":"SLP adaptor and CSK interacting membrane protein","Uniprot":["Q6UWF3"],"Chromosome":"17","Position":"5208920-5234860","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"49.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"B-cells":"78.9","Hofbauer cells":"42.8","Kupffer cells":"89.4","Macrophages":"63.9","monocytes":"119.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"2.7"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"classical monocyte":"110.6","intermediate monocyte":"239.0","memory B-cell":"145.8","myeloid DC":"84.2","naive B-cell":"124.5","non-classical monocyte":"265.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"145.8","dendritic cells":"84.2","monocytes":"265.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"15.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006117"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA006117":"AB_1858633"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"}},{"Gene":"SCIN","Gene synonym":["KIAA1905"],"Ensembl":"ENSG00000006747","Gene description":"Scinderin","Uniprot":["Q9Y6U3"],"Chromosome":"7","Position":"12570577-12660182","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin capping","Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"46.4","kidney":"47.1","placenta":"77.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"303.2","Early spermatids":"108.0","Paneth cells":"164.8","Proximal enterocytes":"294.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"13.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Stomach - Gastric mucous cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020518","HPA024264"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2300000","Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA020518":"AB_1856619","HPA024264":"AB_1856621"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.26e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"}},{"Gene":"SCLY","Gene synonym":["SCL"],"Ensembl":"ENSG00000132330","Gene description":"Selenocysteine lyase","Uniprot":["Q96I15"],"Chromosome":"2","Position":"238060924-238099413","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Lyase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"39.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Early spermatids":"61.4","Late spermatids":"162.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020190","HPA055760"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"300000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA020190":null,"HPA055760":"AB_2682910"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"}},{"Gene":"SCN10A","Gene synonym":["hPN3","Nav1.8","PN3","SNS"],"Ensembl":"ENSG00000185313","Gene description":"Sodium voltage-gated channel alpha subunit 10","Uniprot":["Q9Y5Y9"],"Chromosome":"3","Position":"38696802-38816286","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SCN11A","Gene synonym":["NaN","Nav1.9","SCN12A","SNS-2"],"Ensembl":"ENSG00000168356","Gene description":"Sodium voltage-gated channel alpha subunit 11","Uniprot":["Q9UI33"],"Chromosome":"3","Position":"38845764-39052157","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","FDA approved drug targets","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"3.0","placenta":"1.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"6.1","Astrocytes":"7.6","Early spermatids":"7.2","Late spermatids":"5.1","Spermatocytes":"18.7","Spermatogonia":"12.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036746","HPA036747"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 47: Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036746":"AB_10696785","HPA036747":"AB_2675287"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-4"}},{"Gene":"SCN1A","Gene synonym":["FEB3","GEFSP2","HBSCI","NAC1","Nav1.1","SCN1","SMEI"],"Ensembl":"ENSG00000144285","Gene description":"Sodium voltage-gated channel alpha subunit 1","Uniprot":["P35498"],"Chromosome":"2","Position":"165984641-166149214","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Autism","Autism spectrum disorder","Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"24.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Excitatory neurons":"404.6","Inhibitory neurons":"483.9","Oligodendrocyte precursor cells":"662.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"1.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078664"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA078664":"AB_2686888"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-1"}},{"Gene":"SCN1B","Gene synonym":[],"Ensembl":"ENSG00000105711","Gene description":"Sodium voltage-gated channel beta subunit 1","Uniprot":["Q07699"],"Chromosome":"19","Position":"35030470-35040449","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion","Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Atrial fibrillation","Brugada syndrome","Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"256.5","skeletal muscle":"572.0","tongue":"227.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"66.8","Excitatory neurons":"49.8","Horizontal cells":"64.7","Inhibitory neurons":"47.4","Skeletal myocytes":"153.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"22.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebral cortex":"349.1"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.38e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"}},{"Gene":"SCN2A","Gene synonym":["HBSCI","HBSCII","Nav1.2","SCN2A1","SCN2A2"],"Ensembl":"ENSG00000136531","Gene description":"Sodium voltage-gated channel alpha subunit 2","Uniprot":["Q99250"],"Chromosome":"2","Position":"165194993-165392310","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"26.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"434.0","Inhibitory neurons":"356.1","Oligodendrocyte precursor cells":"235.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"6.1"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enteroendocrine cells","Testis - Peritubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022567"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022567":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"}},{"Gene":"SCN2B","Gene synonym":[],"Ensembl":"ENSG00000149575","Gene description":"Sodium voltage-gated channel beta subunit 2","Uniprot":["O60939"],"Chromosome":"11","Position":"118162806-118176639","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Atrial fibrillation","Brugada syndrome","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"34.0","heart muscle":"12.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"9.3","Cardiomyocytes":"15.2","Excitatory neurons":"21.6","Horizontal cells":"30.8","Inhibitory neurons":"31.2","Schwann cells":"10.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.3","thyroid cancer":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-3"}},{"Gene":"SCN3A","Gene synonym":["Nav1.3"],"Ensembl":"ENSG00000153253","Gene description":"Sodium voltage-gated channel alpha subunit 3","Uniprot":["Q9NY46"],"Chromosome":"2","Position":"165087526-165204050","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"16.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"97.0","Excitatory neurons":"223.9","Inhibitory neurons":"165.0","Oligodendrocyte precursor cells":"343.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"3.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"30","RNA blood cell specific nTPM":{"memory B-cell":"13.2","naive B-cell":"15.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"B-cells":"15.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"7.9","Neuroblastoma":"7.1"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035396"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035396":"AB_2674607"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"}},{"Gene":"SCN3B","Gene synonym":["HSA243396"],"Ensembl":"ENSG00000166257","Gene description":"Sodium voltage-gated channel beta subunit 3","Uniprot":["Q9NY72"],"Chromosome":"11","Position":"123629187-123655244","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Atrial fibrillation","Brugada syndrome","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"54.2","pituitary gland":"28.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endothelial cells":"24.1","Excitatory neurons":"57.8","Horizontal cells":"84.0","Inhibitory neurons":"34.7","Late spermatids":"33.5","Skeletal myocytes":"56.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.2"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"amygdala":"34.3","basal ganglia":"40.6","cerebral cortex":"49.7","hippocampal formation":"54.2","white matter":"15.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Neuroblastoma":"17.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"166.1"},"Antibody":["HPA041707"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA041707":"AB_2732493"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"}},{"Gene":"SCN4A","Gene synonym":["HYKPP","HYPP","Nav1.4","SkM1"],"Ensembl":"ENSG00000007314","Gene description":"Sodium voltage-gated channel alpha subunit 4","Uniprot":["P35499"],"Chromosome":"17","Position":"63938554-63972918","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Congenital myasthenic syndrome","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"137.4","tongue":"54.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Adipocytes":"40.8","Skeletal myocytes":"38.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"2.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"7.7"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070997"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA070997":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"}},{"Gene":"SCN4B","Gene synonym":["LQT10"],"Ensembl":"ENSG00000177098","Gene description":"Sodium voltage-gated channel beta subunit 4","Uniprot":["Q8IWT1"],"Chromosome":"11","Position":"118133377-118152888","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Atrial fibrillation","Disease variant","FDA approved drug targets","Long QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"109.6","tongue":"56.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"10.3","Excitatory neurons":"18.0","Inhibitory neurons":"8.1","Late spermatids":"8.9","Sertoli cells":"19.3","Smooth muscle cells":"25.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"8.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"basal ganglia":"816.3"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"134.6"},"Antibody":["HPA017293"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017293":"AB_2184174"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-4"}},{"Gene":"SCN5A","Gene synonym":["CDCD2","CMD1E","CMPD2","HB1","HB2","HBBD","HH1","ICCD","IVF","LQT3","Nav1.5","PFHB1","SSS1"],"Ensembl":"ENSG00000183873","Gene description":"Sodium voltage-gated channel alpha subunit 5","Uniprot":["Q14524"],"Chromosome":"3","Position":"38548057-38649687","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Calmodulin-binding","Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Atrial fibrillation","Brugada syndrome","Cardiomyopathy","Disease variant","FDA approved drug targets","Long QT syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"heart muscle":"42.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"58.5","Cone photoreceptor cells":"34.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"5.2","Sarcoma":"5.0"},"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Colon - Colon enteroendocrine cells","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"amygdala":"3.1","basal ganglia":"10.1","hypothalamus":"6.0"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"5.4"},"Antibody":["HPA063346"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Nucleoli"],"Antibody RRID":{"HPA063346":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"}},{"Gene":"SCN7A","Gene synonym":["NaG","Nav2.1","Nav2.2","SCN6A"],"Ensembl":"ENSG00000136546","Gene description":"Sodium voltage-gated channel alpha subunit 7","Uniprot":["Q01118"],"Chromosome":"2","Position":"166403573-166611482","Protein class":["FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"45.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Schwann cells":"720.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Rhabdoid":"17.4"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"7.6"},"Antibody":["HPA072715"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA072715":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-4"}},{"Gene":"SCN8A","Gene synonym":["CerIII","CIAT","MED","NaCh6","Nav1.6","PN4"],"Ensembl":"ENSG00000196876","Gene description":"Sodium voltage-gated channel alpha subunit 8","Uniprot":["Q9UQD0"],"Chromosome":"12","Position":"51590266-51812864","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"35.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"331.9","Inhibitory neurons":"274.1","Oligodendrocyte precursor cells":"100.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"35.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022169","HPA043937","HPA073590"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cell Junctions"],"Antibody RRID":{"CAB022169":null,"HPA043937":null,"HPA073590":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"}},{"Gene":"SCN9A","Gene synonym":["ETHA","Nav1.7","NE-NA","NENA","PN1"],"Ensembl":"ENSG00000169432","Gene description":"Sodium voltage-gated channel alpha subunit 9","Uniprot":["Q15858"],"Chromosome":"2","Position":"166195185-166376001","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":["Ion channel","Sodium channel","Voltage-gated channel"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"21.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"112.3","Hofbauer cells":"65.6","Langerhans cells":"53.8","Oligodendrocyte precursor cells":"128.0","Schwann cells":"90.9","Sertoli cells":"74.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"plasmacytoid DC":"23.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"dendritic cells":"23.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"44.9"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"hypothalamus":"9.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013679","HPA061843"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Plasma membrane","Actin filaments","Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"CAB013679":null,"HPA061843":"AB_2684625"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.30e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"}},{"Gene":"SCNN1A","Gene synonym":["ENaCalpha","SCNN1"],"Ensembl":"ENSG00000111319","Gene description":"Sodium channel epithelial 1 subunit alpha","Uniprot":["P37088"],"Chromosome":"12","Position":"6346843-6377730","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sensory transduction","Sodium transport","Taste","Transport"],"Molecular function":["Ion channel","Sodium channel"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"157.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"226.5","Alveolar cells type 2":"187.3","Distal enterocytes":"120.6","Glandular and luminal cells":"185.6","Intestinal goblet cells":"186.4","Salivary duct cells":"181.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"hippocampal formation":"6.8"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Colon - Colon enterocytes","Lung - Alveolar cells type 2","Prostate - Prostate basal glandular cells","Stomach - Gastric mucous cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012743"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012743":"AB_1856627"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.86e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.30e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.21e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"}},{"Gene":"SCNN1B","Gene synonym":["ENaCbeta"],"Ensembl":"ENSG00000168447","Gene description":"Sodium channel epithelial 1 subunit beta","Uniprot":["P51168"],"Chromosome":"16","Position":"23278231-23381294","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sensory transduction","Sodium transport","Taste","Transport"],"Molecular function":["Ion channel","Sodium channel"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"82.8","intestine":"94.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"94.7","Club cells":"57.7","Distal enterocytes":"198.1","Ionocytes":"49.4","Salivary duct cells":"78.1","Suprabasal keratinocytes":"51.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"26.4"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"9","RNA brain regional specific nTPM":{"cerebellum":"1.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"29.9","Sarcoma":"37.7"},"RNA tissue cell type enrichment":["Prostate - Prostate basal glandular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebellum":"1.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015612"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015612":"AB_1856629"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.09e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"}},{"Gene":"SCNN1D","Gene synonym":["dNaCh","ENaCdelta"],"Ensembl":"ENSG00000162572","Gene description":"Sodium channel epithelial 1 subunit delta","Uniprot":["P51172"],"Chromosome":"1","Position":"1280436-1292029","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sensory transduction","Sodium transport","Taste","Transport"],"Molecular function":["Ion channel","Sodium channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"35.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"10.4","Early spermatids":"9.7","Horizontal cells":"8.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026884"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Plasma membrane","Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA026884":"AB_10601501"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.60e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"}},{"Gene":"SCNN1G","Gene synonym":["ENaCgamma","SCNEG"],"Ensembl":"ENSG00000166828","Gene description":"Sodium channel epithelial 1 subunit gamma","Uniprot":["P51170"],"Chromosome":"16","Position":"23182745-23216883","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sensory transduction","Sodium transport","Taste","Transport"],"Molecular function":["Ion channel","Sodium channel"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"42.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"22.0","Club cells":"26.4","Collecting duct cells":"41.4","Gastric mucus-secreting cells":"14.9","Glandular and luminal cells":"16.7","Ionocytes":"17.9","Salivary duct cells":"27.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"15.6"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"4.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"15.9"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Pancreas - Ductal cells","Prostate - Prostate basal glandular cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"13","RNA mouse brain regional specific nTPM":{"cerebellum":"2.5"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071194"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA071194":"AB_2686359"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.20e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"}},{"Gene":"SCO1","Gene synonym":["SCOD1"],"Ensembl":"ENSG00000133028","Gene description":"Synthesis of cytochrome C oxidase 1","Uniprot":["O75880"],"Chromosome":"17","Position":"10672474-10698375","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"108.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021565","HPA021579"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021565":"AB_1856631","HPA021579":"AB_1856632"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.69e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.44e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"}},{"Gene":"SCO2","Gene synonym":["MYP6","SCO1L"],"Ensembl":"ENSG00000284194","Gene description":"Synthesis of cytochrome C oxidase 2","Uniprot":["O43819"],"Chromosome":"22","Position":"50523568-50526461","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Cardiomyopathy","Disease variant","Leigh syndrome","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046943","HPA056254"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA046943":"AB_2732536","HPA056254":"AB_2683080"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SCRIB","Gene synonym":["KIAA0147","SCRB1","Vartul"],"Ensembl":"ENSG00000180900","Gene description":"Scribble planar cell polarity protein","Uniprot":["Q14160"],"Chromosome":"8","Position":"143790920-143815773","Protein class":["Disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Host-virus interaction","Inhibition of host innate immune response by virus","Inhibition of host interferon signaling pathway by virus","Inhibition of host STAT1 by virus","Inhibition of host STAT2 by virus","Viral immunoevasion"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"100.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015463","CAB022081","HPA023557","HPA064312"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nucleoplasm","Rods & Rings"],"Antibody RRID":{"CAB015463":"AB_2238926","CAB022081":null,"HPA023557":"AB_2671238","HPA064312":"AB_2685242"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"}},{"Gene":"SCTR","Gene synonym":[],"Ensembl":"ENSG00000080293","Gene description":"Secretin receptor","Uniprot":["P47872"],"Chromosome":"2","Position":"119439843-119525301","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"26.6","pancreas":"68.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 2":"28.5","Ductal cells":"91.0","Exocrine glandular cells":"79.3","Pancreatic endocrine cells":"29.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"15.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"1.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007269"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007269":"AB_1856640"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"}},{"Gene":"SDC1","Gene synonym":["CD138","SDC","SYND1","syndecan"],"Ensembl":"ENSG00000115884","Gene description":"Syndecan 1","Uniprot":["P18827"],"Chromosome":"2","Position":"20200797-20225433","Protein class":["Cancer-related genes","CD markers","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"491.6","liver":"484.7","skin 1":"447.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"261.8","Hepatocytes":"521.4","Squamous epithelial cells":"277.8","Suprabasal keratinocytes":"460.3","Syncytiotrophoblasts":"426.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"midbrain":"17.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"549.2","Myeloma":"636.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Alveolar cells type 2","Stomach - Gastric mucous cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002424","HPA006185","HPA067477"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Focal adhesion sites"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":63100000,"Blood concentration - Conc. blood MS [pg\/L]":"3100000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"CAB002424":"AB_442050","HPA006185":"AB_1857705","HPA067477":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.22e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.02e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"}},{"Gene":"SDC2","Gene synonym":["CD362","fibroglycan","HSPG","HSPG1","SYND2"],"Ensembl":"ENSG00000169439","Gene description":"Syndecan 2","Uniprot":["P34741"],"Chromosome":"8","Position":"96493813-96611790","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"460.8","thyroid gland":"424.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"185.2","Hepatocytes":"230.5","Langerhans cells":"159.2","Smooth muscle cells":"136.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"13.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"13.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Fibroblasts","Liver - Hepatocytes","Skeletal muscle - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025123","HPA044416","HPA074427"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB025123":null,"HPA044416":"AB_2678934","HPA074427":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"SDC3","Gene synonym":["N-syndecan","SYND3"],"Ensembl":"ENSG00000162512","Gene description":"Syndecan 3","Uniprot":["O75056"],"Chromosome":"1","Position":"30869466-30908758","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"140.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"62.6","Endometrial stromal cells":"59.6","Late spermatids":"82.5","Oligodendrocyte precursor cells":"104.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"115.2","melanoma":"102.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"187.0"},"RNA tissue cell type enrichment":["Colon - Smooth muscle cells","Liver - Kupffer cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017087","CAB025786","HPA048085"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB025786":null,"HPA017087":"AB_1857706","HPA048085":"AB_2680256"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.36e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.71e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"}},{"Gene":"SDC4","Gene synonym":["amphiglycan","ryudocan","SYND4"],"Ensembl":"ENSG00000124145","Gene description":"Syndecan 4","Uniprot":["P31431"],"Chromosome":"20","Position":"45325288-45348424","Protein class":["Cancer-related genes","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"410.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"580.4","Exocrine glandular cells":"797.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Pancreas - Ductal cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005716","CAB013240"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB013240":"AB_2533250","HPA005716":"AB_1080160"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.20e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.44e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.67e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"}},{"Gene":"SDF4","Gene synonym":["Cab45"],"Ensembl":"ENSG00000078808","Gene description":"Stromal cell derived factor 4","Uniprot":["Q9BRK5"],"Chromosome":"1","Position":"1216909-1232067","Protein class":["Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":["Exocytosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"301.5","Proximal enterocytes":"350.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011249","HPA011895","CAB015227"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2600000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB015227":null,"HPA011249":"AB_2668468","HPA011895":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.89e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"}},{"Gene":"SDHC","Gene synonym":["CYB560","cybL","PGL3"],"Ensembl":"ENSG00000143252","Gene description":"Succinate dehydrogenase complex subunit C","Uniprot":["Q99643"],"Chromosome":"1","Position":"161314381-161363206","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport","Tricarboxylic acid cycle"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"538.0","Proximal tubular cells":"804.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"}},{"Gene":"SDHD","Gene synonym":["cybS","PGL","PGL1"],"Ensembl":"ENSG00000204370","Gene description":"Succinate dehydrogenase complex subunit D","Uniprot":["O14521"],"Chromosome":"11","Position":"112086824-112120016","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport","Tricarboxylic acid cycle"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"391.6","Distal tubular cells":"429.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045727"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045727":"AB_10963114"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.99e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"}},{"Gene":"SDK1","Gene synonym":["FLJ31425"],"Ensembl":"ENSG00000146555","Gene description":"Sidekick cell adhesion molecule 1","Uniprot":["Q7Z5N4"],"Chromosome":"7","Position":"3301252-4269000","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"12.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"218.9","Inhibitory neurons":"539.8","Late spermatids":"198.3","Microglial cells":"196.1","Oligodendrocyte precursor cells":"107.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Fibroblast_2","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011392"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9500000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA011392":"AB_1856648"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.08e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"SDK2","Gene synonym":["FLJ10832","KIAA1514"],"Ensembl":"ENSG00000069188","Gene description":"Sidekick cell adhesion molecule 2","Uniprot":["Q58EX2"],"Chromosome":"17","Position":"73334384-73644445","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.5","cervix":"5.5","testis":"9.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"15.9","Excitatory neurons":"18.5","Extravillous trophoblasts":"18.8","Inhibitory neurons":"14.4","Late spermatids":"17.2","Syncytiotrophoblasts":"15.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"7.2"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Liver - Hepatic stellate cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014725"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5300000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA014725":"AB_2183303"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"}},{"Gene":"SDR16C5","Gene synonym":["EPHD-2","RDH-E2","RDHE2"],"Ensembl":"ENSG00000170786","Gene description":"Short chain dehydrogenase\/reductase family 16C member 5","Uniprot":["Q8N3Y7"],"Chromosome":"8","Position":"56300005-56320776","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"51.9","lung":"34.4","skin 1":"62.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"215.5","Alveolar cells type 2":"457.8","Basal respiratory cells":"335.5","Ionocytes":"292.4","Suprabasal keratinocytes":"237.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"35","RNA blood cell specific nTPM":{"memory B-cell":"4.7","naive B-cell":"2.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"47","RNA blood lineage specific nTPM":{"B-cells":"4.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"15.0"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Lung - Alveolar cells type 2","Prostate - Urothelial cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025224"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA025224":"AB_1856163"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.88e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"}},{"Gene":"SDR42E1","Gene synonym":["HSPC105"],"Ensembl":"ENSG00000184860","Gene description":"Short chain dehydrogenase\/reductase family 42E, member 1","Uniprot":["Q8WUS8"],"Chromosome":"16","Position":"81988855-82011481","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"9.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"2.3","NK-cells":"2.0","T-cells":"2.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Skin - Keratinocyte (other)","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014388"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014388":"AB_1851226"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"}},{"Gene":"SDR42E2","Gene synonym":[],"Ensembl":"ENSG00000183921","Gene description":"Short chain dehydrogenase\/reductase family 42E, member 2","Uniprot":["A6NKP2"],"Chromosome":"16","Position":"22165583-22191754","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"3.2","choroid plexus":"1.8","fallopian tube":"2.1","pituitary gland":"1.2","testis":"2.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"28.1","Proximal enterocytes":"36.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"4.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"4.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"}},{"Gene":"SEC11A","Gene synonym":["SEC11L1","sid2895","SPC18","SPCS4A"],"Ensembl":"ENSG00000140612","Gene description":"SEC11 homolog A, signal peptidase complex subunit","Uniprot":["P67812"],"Chromosome":"15","Position":"84669538-84716460","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"742.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047533"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA047533":"AB_2680078"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.94e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.99e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.95e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"}},{"Gene":"SEC11C","Gene synonym":["SEC11L3","SPC21","SPCS4C"],"Ensembl":"ENSG00000166562","Gene description":"SEC11 homolog C, signal peptidase complex subunit","Uniprot":["Q9BY50"],"Chromosome":"18","Position":"59139866-59158832","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"1348.3","Prostatic glandular cells":"920.7","Serous glandular cells":"648.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"904.4"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026816","HPA047533"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA026816":"AB_10602089","HPA047533":"AB_2680078"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"}},{"Gene":"SEC14L1","Gene synonym":["PRELID4A","SEC14L"],"Ensembl":"ENSG00000129657","Gene description":"SEC14 like lipid binding 1","Uniprot":["Q92503"],"Chromosome":"17","Position":"77088749-77217101","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Signal transduction inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"415.6","Late spermatids":"763.4","monocytes":"307.2","Plasma cells":"272.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"355.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"355.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Skin - Endothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021463","HPA028703"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA021463":"AB_2670712","HPA028703":"AB_10602300"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"}},{"Gene":"SEC16A","Gene synonym":["KIAA0310","p250","Sec16L"],"Ensembl":"ENSG00000148396","Gene description":"SEC16 homolog A, endoplasmic reticulum export factor","Uniprot":["O15027"],"Chromosome":"9","Position":"136440096-136483759","Protein class":["Predicted intracellular proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005684"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"48000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA005684":"AB_1079189"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.30e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.47e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"}},{"Gene":"SEC22A","Gene synonym":["SEC22L2"],"Ensembl":"ENSG00000121542","Gene description":"SEC22 homolog A, vesicle trafficking protein","Uniprot":["Q96IW7"],"Chromosome":"3","Position":"123201927-123274136","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"66.5","Inhibitory neurons":"66.0","Oligodendrocytes":"70.8","Spermatocytes":"67.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039127"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA039127":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-1"}},{"Gene":"SEC22B","Gene synonym":["ERS-24","SEC22L1"],"Ensembl":"ENSG00000265808","Gene description":"SEC22 homolog B, vesicle trafficking protein","Uniprot":["O75396"],"Chromosome":"1","Position":"120150898-120176520","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB079017"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"91000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079017":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.58e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"}},{"Gene":"SEC22C","Gene synonym":["MGC13261","MGC5373","SEC22L3"],"Ensembl":"ENSG00000093183","Gene description":"SEC22 homolog C, vesicle trafficking protein","Uniprot":["Q9BRL7"],"Chromosome":"3","Position":"42547969-42601080","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031242"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA031242":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.04e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"}},{"Gene":"SEC61A1","Gene synonym":[],"Ensembl":"ENSG00000058262","Gene description":"SEC61 translocon subunit alpha 1","Uniprot":["P61619"],"Chromosome":"3","Position":"128051641-128071683","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":["Chaperone"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"230.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022076"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB022076":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.82e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.07e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.84e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"}},{"Gene":"SEC61A2","Gene synonym":["FLJ10578"],"Ensembl":"ENSG00000065665","Gene description":"SEC61 translocon subunit alpha 2","Uniprot":["Q9H9S3"],"Chromosome":"10","Position":"12129637-12169961","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"40.6","Inhibitory neurons":"41.5","Late spermatids":"31.4","Oligodendrocytes":"41.8","Spermatocytes":"36.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.08e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.22e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.75e-4"}},{"Gene":"SEC61B","Gene synonym":[],"Ensembl":"ENSG00000106803","Gene description":"SEC61 translocon subunit beta","Uniprot":["P60468"],"Chromosome":"9","Position":"99222064-99230615","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"1675.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049407"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA049407":"AB_2680750"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.26e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"}},{"Gene":"SEC61G","Gene synonym":["SSS1"],"Ensembl":"ENSG00000132432","Gene description":"SEC61 translocon subunit gamma","Uniprot":["P60059"],"Chromosome":"7","Position":"54752250-54759974","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"333.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053196"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"37000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053196":"AB_2682077"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.85e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.60e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"}},{"Gene":"SEC62","Gene synonym":["Dtrp1","HTP1","TLOC1"],"Ensembl":"ENSG00000008952","Gene description":"SEC62 homolog, preprotein translocation factor","Uniprot":["Q99442"],"Chromosome":"3","Position":"169966635-169998373","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014059","HPA061450"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"HPA014059":"AB_1858029","HPA061450":"AB_2684524"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"}},{"Gene":"SEC63","Gene synonym":["DNAJC23","ERdj2","PRO2507","SEC63L"],"Ensembl":"ENSG00000025796","Gene description":"SEC63 homolog, protein translocation regulator","Uniprot":["Q9UGP8"],"Chromosome":"6","Position":"107867756-107958208","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":["Chaperone"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053295","HPA060535"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA053295":"AB_2682105","HPA060535":"AB_2684312"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.32e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.01e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"}},{"Gene":"SECTM1","Gene synonym":["K12"],"Ensembl":"ENSG00000141574","Gene description":"Secreted and transmembrane 1","Uniprot":["Q8WVN6"],"Chromosome":"17","Position":"82321024-82334074","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"90.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"107.0","Macrophages":"36.4","monocytes":"89.9","Mucus glandular cells":"49.0","Proximal enterocytes":"55.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"154.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"154.2","monocytes":"58.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"86.2"},"RNA tissue cell type enrichment":["Stomach - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051214"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051214":"AB_2732565"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"}},{"Gene":"SEL1L","Gene synonym":["Hrd3","IBD2","SEL1L1"],"Ensembl":"ENSG00000071537","Gene description":"SEL1L adaptor subunit of ERAD E3 ubiquitin ligase","Uniprot":["Q9UBV2"],"Chromosome":"14","Position":"81471547-81533853","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction","Notch signaling pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"pancreas":"403.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"223.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024267"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024267":"AB_1856659"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"}},{"Gene":"SEL1L2","Gene synonym":["C20orf50","DKFZp434C1826"],"Ensembl":"ENSG00000101251","Gene description":"SEL1L2 adaptor subunit of ERAD E3 ligase","Uniprot":["Q5TEA6"],"Chromosome":"20","Position":"13849247-13996443","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"testis":"7.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"181.6","Late spermatids":"168.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059121"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059121":"AB_2683911"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"}},{"Gene":"SEL1L3","Gene synonym":["KIAA0746"],"Ensembl":"ENSG00000091490","Gene description":"SEL1L family member 3","Uniprot":["Q68CR1"],"Chromosome":"4","Position":"25747433-25863760","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"128.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"432.4","Plasma cells":"270.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"cerebellum":"82.1"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"42.0","naive B-cell":"41.8","plasmacytoid DC":"38.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"42.0","dendritic cells":"38.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Plasma cells","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"cerebellum":"100.4"},"Antibody":["HPA039355","HPA040045","HPA058792"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA039355":null,"HPA040045":"AB_10796116","HPA058792":"AB_2683822"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.33e-4"}},{"Gene":"SELE","Gene synonym":["CD62E","ELAM","ELAM1","ESEL"],"Ensembl":"ENSG00000007908","Gene description":"Selectin E","Uniprot":["P16581"],"Chromosome":"1","Position":"169722640-169764705","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"urinary bladder":"56.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Endothelial cells":"456.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002143"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":8140000,"Blood concentration - Conc. blood MS [pg\/L]":"180000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002143":"AB_563608"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"}},{"Gene":"SELENOI","Gene synonym":["EPT1","KIAA1724","SELI","SEPI"],"Ensembl":"ENSG00000138018","Gene description":"Selenoprotein I","Uniprot":["Q9C0D9"],"Chromosome":"2","Position":"26308547-26395891","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064125"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064125":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"}},{"Gene":"SELENOK","Gene synonym":["SELK"],"Ensembl":"ENSG00000113811","Gene description":"Selenoprotein K","Uniprot":["Q9Y6D0"],"Chromosome":"3","Position":"53884417-53891962","Protein class":["Predicted membrane proteins"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"1375.7","Langerhans cells":"2779.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"471.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"471.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008196"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008196":"AB_1856665"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.18e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.76e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"}},{"Gene":"SELENOP","Gene synonym":["SELP","SeP","SEPP","SEPP1"],"Ensembl":"ENSG00000250722","Gene description":"Selenoprotein P","Uniprot":["P49908"],"Chromosome":"5","Position":"42799880-42887392","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"2087.6","liver":"6268.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"3174.3","Proximal enterocytes":"5487.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"116.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"197.2"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Liver - Hepatocytes","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036287"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":2220000000,"Blood concentration - Conc. blood MS [pg\/L]":"1800000000","Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA036287":"AB_10794618"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.97e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"}},{"Gene":"SELENOS","Gene synonym":["AD-015","MGC2553","SBBI8","SELS","SEPS1","VIMP"],"Ensembl":"ENSG00000131871","Gene description":"Selenoprotein S","Uniprot":["Q9BQE4"],"Chromosome":"15","Position":"101270817-101277500","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"631.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"606.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"606.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010025"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA010025":"AB_1079900"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.19e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"}},{"Gene":"SELENOT","Gene synonym":["SELT"],"Ensembl":"ENSG00000198843","Gene description":"Selenoprotein T","Uniprot":["P62341"],"Chromosome":"3","Position":"150602875-150630445","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"548.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039780"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039780":"AB_10805594"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"}},{"Gene":"SELL","Gene synonym":["CD62L","hLHRc","LAM-1","LAM1","Leu-8","LNHR","LSEL","Lyam-1","LYAM1","PLNHR"],"Ensembl":"ENSG00000188404","Gene description":"Selectin L","Uniprot":["P14151"],"Chromosome":"1","Position":"169690665-169711702","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"150.4","lymphoid tissue":"231.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"219.7","dendritic cells":"372.3","Kupffer cells":"151.8","Macrophages":"79.3","monocytes":"107.9","NK-cells":"89.0","T-cells":"114.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"31.9","lymphoma":"22.0","Myeloma":"15.0"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2","Skeletal muscle - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002144","HPA051972"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4700000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002144":"AB_563862","HPA051972":"AB_2797242"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.76e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.25e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.43e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.14e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.96e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"}},{"Gene":"SELP","Gene synonym":["CD62","CD62P","GMP140","GRMP","PADGEM","PSEL"],"Ensembl":"ENSG00000174175","Gene description":"Selectin P","Uniprot":["P16109"],"Chromosome":"1","Position":"169588849-169630193","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"24.9","Endothelial cells":"43.3","Smooth muscle cells":"9.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"8.3","T-reg":"8.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"8.3","T-cells":"8.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"2.1"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Prostate - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002145","HPA002655","HPA005990"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"520000000","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002145":"AB_563984","HPA002655":"AB_1078480","HPA005990":"AB_1078479"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.12e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"}},{"Gene":"SEM1","Gene synonym":["C7orf76","DSS1","ECD","FLJ42280","SHFD1","Shfdg1","SHFM1","SHSF1"],"Ensembl":"ENSG00000127922","Gene description":"SEM1 26S proteasome complex subunit","Uniprot":["P60896","Q6ZVN7"],"Chromosome":"7","Position":"96481626-96709891","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020429","HPA072648"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA020429":"AB_1859527","HPA072648":"AB_2686543"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.52e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.00e-5"}},{"Gene":"SEMA3D","Gene synonym":["coll-2","Sema-Z2"],"Ensembl":"ENSG00000153993","Gene description":"Semaphorin 3D","Uniprot":["O95025"],"Chromosome":"7","Position":"84995553-85186855","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"47.8","thyroid gland":"45.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"111.5","Late spermatids":"70.2","Leydig cells":"50.9","Peritubular cells":"61.7","Prostatic glandular cells":"54.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"28.8","Sarcoma":"79.6"},"RNA tissue cell type enrichment":["Heart muscle - Smooth muscle cells","Liver - Hepatic stellate cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011183","HPA037522"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA011183":null,"HPA037522":"AB_10672494"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-3"}},{"Gene":"SEMA3F","Gene synonym":["Sema4","SEMAK"],"Ensembl":"ENSG00000001617","Gene description":"Semaphorin 3F","Uniprot":["Q13275"],"Chromosome":"3","Position":"50155045-50189075","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"100.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"38.7","Basal prostatic cells":"33.5","Bipolar cells":"24.3","Endothelial cells":"28.9","Suprabasal keratinocytes":"35.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Lung - Endothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035008"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1700000,"Blood concentration - Conc. blood MS [pg\/L]":"7900000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035008":"AB_10604091"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-3"}},{"Gene":"SEMA4A","Gene synonym":["CORD10","FLJ12287","SEMAB","SemB"],"Ensembl":"ENSG00000196189","Gene description":"Semaphorin 4A","Uniprot":["Q9H3S1"],"Chromosome":"1","Position":"156147366-156177752","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Angiogenesis","Differentiation","Immunity","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Cone-rod dystrophy","Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"51.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"85.3","Mucus glandular cells":"70.2","Salivary duct cells":"103.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"123.9","eosinophil":"120.2","intermediate monocyte":"132.7","myeloid DC":"183.0","neutrophil":"210.7","non-classical monocyte":"76.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"dendritic cells":"183.0","granulocytes":"210.7","monocytes":"132.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"100.1"},"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069136"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069136":"AB_2686093"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"}},{"Gene":"SEMA4B","Gene synonym":["KIAA1745","MGC131831","SEMAC","SemC"],"Ensembl":"ENSG00000185033","Gene description":"Semaphorin 4B","Uniprot":["Q9NPR2"],"Chromosome":"15","Position":"90160604-90229679","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"124.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"81.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"16.9","naive B-cell":"14.9","neutrophil":"5.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Prostate - Urothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013372"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"61000000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA013372":"AB_1856670"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.33e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"}},{"Gene":"SEMA4C","Gene synonym":["Semacl1","Semaf","SEMAI"],"Ensembl":"ENSG00000168758","Gene description":"Semaphorin 4C","Uniprot":["Q9C0C4"],"Chromosome":"2","Position":"96859718-96870757","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"152.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011090"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"700000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011090":"AB_2185705"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.53e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.50e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-1"}},{"Gene":"SEMA4D","Gene synonym":["C9orf164","CD100","coll-4","FLJ39737","SEMAJ"],"Ensembl":"ENSG00000187764","Gene description":"Semaphorin 4D","Uniprot":["Q92854"],"Chromosome":"9","Position":"89360787-89498130","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"260.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"106.6","Oligodendrocytes":"293.1","T-cells":"95.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"45.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Colon - T-cells","Skin - Keratinocyte (granular)","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015662","HPA023277"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7500000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015662":"AB_1856671","HPA023277":"AB_1856672"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.17e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.06e-5"}},{"Gene":"SEMA4F","Gene synonym":["SEMAM","SEMAW"],"Ensembl":"ENSG00000135622","Gene description":"Ssemaphorin 4F","Uniprot":["O95754"],"Chromosome":"2","Position":"74654228-74683853","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"43.8","Inhibitory neurons":"22.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"22.6"},"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064095"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064095":"AB_2732710"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.94e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.96e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.74e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.94e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"}},{"Gene":"SEMA4G","Gene synonym":["FLJ20590","KIAA1619"],"Ensembl":"ENSG00000095539","Gene description":"Semaphorin 4G","Uniprot":["Q9NTN9"],"Chromosome":"10","Position":"100969518-100985871","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"84.6","liver":"102.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"56.2","Hepatocytes":"46.6","Intestinal goblet cells":"39.0","Paneth cells":"38.3","Proximal enterocytes":"46.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes","Prostate - Prostate glandular cells","Skin - Keratinocyte (granular)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038362","HPA077752"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Lipid droplets"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Vesicles","Lipid droplets"],"Subcellular additional location":null,"Antibody RRID":{"HPA038362":"AB_10669524","HPA077752":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"}},{"Gene":"SEMA5A","Gene synonym":["SEMAF","semF"],"Ensembl":"ENSG00000112902","Gene description":"Semaphorin 5A","Uniprot":["Q13591"],"Chromosome":"5","Position":"9035033-9546075","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"35.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"1139.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"plasmacytoid DC":"2.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"2.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Podocytes","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004632"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004632":"AB_1079905"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.45e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.66e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"}},{"Gene":"SEMA5B","Gene synonym":["FLJ10372","KIAA1445","SEMAG","SemG"],"Ensembl":"ENSG00000082684","Gene description":"Semaphorin 5B","Uniprot":["Q9P283"],"Chromosome":"3","Position":"122909082-123028605","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"16.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"9.2","Bipolar cells":"7.1","Excitatory neurons":"30.2","Oligodendrocyte precursor cells":"43.3","Smooth muscle cells":"9.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"18.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"13.9","Kidney cancer":"20.8"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066548"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA066548":"AB_2685689"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.57e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"}},{"Gene":"SEMA6A","Gene synonym":["HT018","KIAA1368","SEMA","SEMA6A1","SEMAQ"],"Ensembl":"ENSG00000092421","Gene description":"Semaphorin 6A","Uniprot":["Q9H2E6"],"Chromosome":"5","Position":"116443555-116574823","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"60.1","brain":"75.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"126.5","Oligodendrocyte precursor cells":"132.9","Oligodendrocytes":"293.9","Syncytiotrophoblasts":"354.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"20.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"testis cancer":"221.1"},"RNA tissue cell type enrichment":["Liver - Sinusoid Endothelial cells","Testis - Sertoli cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031264","HPA031265","HPA031267"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"620000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Intermediate filaments"],"Antibody RRID":{"HPA031264":null,"HPA031265":"AB_10610423","HPA031267":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.39e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-3"}},{"Gene":"SEMA6B","Gene synonym":["SEM-SEMA-Y","SEMA-VIB","SEMAN","semaZ"],"Ensembl":"ENSG00000167680","Gene description":"Semaphorin 6B","Uniprot":["Q9H3T3"],"Chromosome":"19","Position":"4542593-4581776","Protein class":["Disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Epilepsy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"72.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"37.8","Endothelial cells":"39.8","Excitatory neurons":"30.2","Horizontal cells":"26.9","Inhibitory neurons":"29.6","Macrophages":"20.5","Oligodendrocyte precursor cells":"18.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"50.0"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025157","HPA055778","HPA058523"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025157":null,"HPA055778":"AB_2682916","HPA058523":"AB_2683741"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.45e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"}},{"Gene":"SEMA6C","Gene synonym":["KIAA1869"],"Ensembl":"ENSG00000143434","Gene description":"Semaphorin 6C","Uniprot":["Q9H3T2"],"Chromosome":"1","Position":"151131685-151146664","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"322.9","tongue":"96.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Skeletal myocytes":"99.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skeletal muscle - Skeletal myocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076150","HPA077625"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Nucleoli fibrillar center","Cytosol"],"Antibody RRID":{"HPA076150":null,"HPA077625":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.27e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.06e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"}},{"Gene":"SEMA6D","Gene synonym":["FLJ11598","KIAA1479"],"Ensembl":"ENSG00000137872","Gene description":"Semaphorin 6D","Uniprot":["Q8NFY4"],"Chromosome":"15","Position":"47184101-47774228","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"38.5","placenta":"43.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"70.5","Cone photoreceptor cells":"86.2","Excitatory neurons":"118.8","Granulosa cells":"69.6","Inhibitory neurons":"313.3","Oligodendrocytes":"132.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"8.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"14.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Ascending Loop of Henle cells","Liver - Hepatic stellate cells","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043109"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA043109":"AB_10793941"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.96e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-4"}},{"Gene":"SEMA7A","Gene synonym":["CD108","H-Sema-L","SEMAL"],"Ensembl":"ENSG00000138623","Gene description":"Semaphorin 7A (John Milton Hagen blood group)","Uniprot":["O75326"],"Chromosome":"15","Position":"74409289-74433958","Protein class":["Blood group antigen proteins","CD markers","Plasma proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Inflammatory response","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"60.1","retina":"34.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"122.3","Exocrine glandular cells":"58.5","Extravillous trophoblasts":"64.4","Granulosa cells":"65.0","Rod photoreceptor cells":"52.5","Syncytiotrophoblasts":"176.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"1.8","eosinophil":"3.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"3.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Endothelial cells","Skin - Keratinocyte (granular)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008210","HPA042273"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"38000000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA008210":null,"HPA042273":"AB_10806234"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.45e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"}},{"Gene":"SENP2","Gene synonym":["AXAM2","DKFZp762A2316","KIAA1331","SMT3IP2"],"Ensembl":"ENSG00000163904","Gene description":"SUMO specific peptidase 2","Uniprot":["Q9HC62"],"Chromosome":"3","Position":"185582496-185633551","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":["mRNA transport","Protein transport","Translocation","Transport","Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"274.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029247","HPA029248"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029247":"AB_10599305","HPA029248":"AB_10601855"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.98e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"}},{"Gene":"SEPHS2","Gene synonym":["SPS2","SPS2b"],"Ensembl":"ENSG00000179918","Gene description":"Selenophosphate synthetase 2","Uniprot":["Q99611"],"Chromosome":"16","Position":"30443631-30445874","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"402.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"394.8","Proximal enterocytes":"392.2","Proximal tubular cells":"328.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047931"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA047931":"AB_2680216"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.35e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"}},{"Gene":"SEPSECS","Gene synonym":["SLA","SLA\/LP"],"Ensembl":"ENSG00000109618","Gene description":"Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase","Uniprot":["Q9HD40"],"Chromosome":"4","Position":"25120014-25160550","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["RNA-binding","Transferase","tRNA-binding"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"26.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"43.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070409"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA070409":"AB_2686265"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"}},{"Gene":"SEPTIN4","Gene synonym":["ARTS","C17orf47","CE5B3","FLJ40121","H5","hCDCREL-2","hucep-7","MART","PNUTL2","SEPT4"],"Ensembl":"ENSG00000108387","Gene description":"Septin 4","Uniprot":["O43236","Q8NEP4"],"Chromosome":"17","Position":"58520250-58544368","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"1288.2","choroid plexus":"593.0","retina":"404.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"166.4","Cone photoreceptor cells":"579.0","Horizontal cells":"571.0","Oligodendrocytes":"154.4","Rod photoreceptor cells":"324.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"8.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"11.1"},"RNA tissue cell type enrichment":["Prostate - Fibroblasts","Skin - Endothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006855","HPA021587","HPA022905","HPA028424"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB006855":null,"HPA021587":"AB_1856686","HPA022905":"AB_1856687","HPA028424":"AB_10601690"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.28e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-3"}},{"Gene":"SERAC1","Gene synonym":["FLJ14917"],"Ensembl":"ENSG00000122335","Gene description":"Serine active site containing 1","Uniprot":["Q96JX3"],"Chromosome":"6","Position":"158109519-158168280","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"79.5","Late spermatids":"125.8","Oligodendrocytes":"44.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025715","HPA025716"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA025715":"AB_1856697","HPA025716":"AB_2185128"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"}},{"Gene":"SERF1A","Gene synonym":["4F5","FAM2A","H4F5","SERF1","SMAM1"],"Ensembl":"ENSG00000172058","Gene description":"Small EDRK-rich factor 1A","Uniprot":["O75920"],"Chromosome":"5","Position":"70900669-70918530","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"64.7","testis":"43.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"2.0","Early spermatids":"2.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"50.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075271"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA075271":"AB_2686740"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"}},{"Gene":"SERF1B","Gene synonym":["FAM2B","H4F5C"],"Ensembl":"ENSG00000205572","Gene description":"Small EDRK-rich factor 1B","Uniprot":["O75920"],"Chromosome":"5","Position":"70025247-70043113","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"154.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"3.1","Early spermatids":"1.7","Late spermatids":"3.2","Schwann cells":"4.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075271"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA075271":"AB_2686740"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"}},{"Gene":"SERINC1","Gene synonym":["KIAA1253","TDE1L","TDE2","TMS-2"],"Ensembl":"ENSG00000111897","Gene description":"Serine incorporator 1","Uniprot":["Q9NRX5"],"Chromosome":"6","Position":"122443351-122471807","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035738","HPA035739"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035738":"AB_10672990","HPA035739":"AB_10669536"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"}},{"Gene":"SERINC2","Gene synonym":["FKSG84","PRO0899","TDE2","TDE2L"],"Ensembl":"ENSG00000168528","Gene description":"Serine incorporator 2","Uniprot":["Q96SA4"],"Chromosome":"1","Position":"31409565-31434680","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"235.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"364.2","Cytotrophoblasts":"458.4","Distal enterocytes":"468.0","Ductal cells":"691.4","Proximal enterocytes":"408.1","Syncytiotrophoblasts":"409.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"plasmacytoid DC":"10.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"10.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Colon enterocytes","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005974"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA005974":"AB_10603239"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.69e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.70e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"}},{"Gene":"SERINC3","Gene synonym":["AIGP1","DIFF33","SBBI99","TDE","TDE1","TMS-1"],"Ensembl":"ENSG00000132824","Gene description":"Serine incorporator 3","Uniprot":["Q13530"],"Chromosome":"20","Position":"44496221-44522085","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Antiviral defense","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"563.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048116"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048116":"AB_2680269"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"}},{"Gene":"SERINC4","Gene synonym":["FLJ40363"],"Ensembl":"ENSG00000184716","Gene description":"Serine incorporator 4","Uniprot":["A6NH21"],"Chromosome":"15","Position":"43794162-43800221","Protein class":["Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"retina":"15.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"58.6","Early spermatids":"16.4","Late spermatids":"47.6","Rod photoreceptor cells":"52.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SERINC5","Gene synonym":["C5orf12","TPO1"],"Ensembl":"ENSG00000164300","Gene description":"Serine incorporator 5","Uniprot":["Q86VE9"],"Chromosome":"5","Position":"80111651-80256048","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Antiviral defense","Host-virus interaction","Immunity","Innate immunity","Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"195.3","Oligodendrocyte precursor cells":"213.7","Oligodendrocytes":"210.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037898","HPA037899"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Vesicles","Centrosome"],"Antibody RRID":{"HPA037898":"AB_10673649","HPA037899":"AB_2675727"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"}},{"Gene":"SERP1","Gene synonym":["FLJ43424","RAMP4"],"Ensembl":"ENSG00000120742","Gene description":"Stress associated endoplasmic reticulum protein 1","Uniprot":["Q9Y6X1"],"Chromosome":"3","Position":"150541998-150603228","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038970"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA038970":"AB_2676296"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"}},{"Gene":"SERP2","Gene synonym":["bA269C23.1","C13orf21"],"Ensembl":"ENSG00000151778","Gene description":"Stress associated endoplasmic reticulum protein family member 2","Uniprot":["Q8N6R1"],"Chromosome":"13","Position":"44373665-44397714","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"87.7","choroid plexus":"53.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"456.1","Late spermatids":"354.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"6.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.6"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"granulocytes":"2.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"4.7"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Late spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038970"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA038970":"AB_2676296"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.94e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"}},{"Gene":"SERPINA10","Gene synonym":["PZI","ZPI"],"Ensembl":"ENSG00000140093","Gene description":"Serpin family A member 10","Uniprot":["Q9UK55"],"Chromosome":"14","Position":"94280460-94293268","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":["Heparin-binding","Protease inhibitor","Serine protease inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"104","RNA tissue specific nTPM":{"liver":"346.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Hepatocytes":"219.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"51","RNA cancer specific FPKM":{"liver cancer":"40.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Liver - Hepatocytes","Pancreas - Alpha cells","Stomach - Gastric enteroendocrine cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048739"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":3960000000,"Blood concentration - Conc. blood MS [pg\/L]":"4700000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA048739":"AB_2797237"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.00e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-3"}},{"Gene":"SERPINA9","Gene synonym":["CENTERIN","GCET1","SERPINA11b"],"Ensembl":"ENSG00000170054","Gene description":"Serpin family A member 9","Uniprot":["Q86WD7"],"Chromosome":"14","Position":"94462717-94479689","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"lymphoid tissue":"72.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"B-cells":"1.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"stomach cancer":"2.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"38","RNA cell line specific nTPM":{"lymphoma":"29.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"16","RNA mouse brain regional specific nTPM":{"basal ganglia":"71.8"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SERPINB2","Gene synonym":["HsT1201","PAI2","PLANH2"],"Ensembl":"ENSG00000197632","Gene description":"Serpin family B member 2","Uniprot":["P05120"],"Chromosome":"18","Position":"63871692-63903888","Protein class":["Cancer-related genes","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Plasminogen activation"],"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"239.1","lymphoid tissue":"81.2","skin 1":"89.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Basal keratinocytes":"1551.5","Suprabasal keratinocytes":"672.5","Syncytiotrophoblasts":"692.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"26.5"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"1.3","thalamus":"1.1"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"22.0","eosinophil":"10.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"22.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"317.0"},"RNA tissue cell type enrichment":["Pancreas - Ductal cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"15","RNA mouse brain regional specific nTPM":{"cerebellum":"2.6"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015480","HPA076596","HPA076608"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2200000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015480":"AB_1855456","HPA076596":null,"HPA076608":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-5"}},{"Gene":"SERPING1","Gene synonym":["C1-INH","C1IN","C1INH","C1NH","HAE1","HAE2"],"Ensembl":"ENSG00000149131","Gene description":"Serpin family G member 1","Uniprot":["P05155"],"Chromosome":"11","Position":"57597387-57619171","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Blood coagulation","Complement pathway","Fibrinolysis","Hemostasis","Immunity","Innate immunity"],"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"2622.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"667.9","Ductal cells":"640.1","Fibroblasts":"830.3","Hepatocytes":"2202.4","Leydig cells":"755.1","Thymic epithelial cells":"1994.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"609.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"65.2","plasmacytoid DC":"60.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"243","RNA blood lineage specific nTPM":{"dendritic cells":"60.6","granulocytes":"65.2","monocytes":"25.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"32.4","testis cancer":"41.8"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Liver - Hepatocytes","Lung - Fibroblast_1","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"194.1"},"Antibody":["CAB026161","HPA048738"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026161":null,"HPA048738":"AB_2680505"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.96e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.03e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"}},{"Gene":"SERTM1","Gene synonym":["C13orf36"],"Ensembl":"ENSG00000180440","Gene description":"Serine rich and transmembrane domain containing 1","Uniprot":["A2A2V5"],"Chromosome":"13","Position":"36674020-36697839","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.9","endometrium 1":"23.9","fallopian tube":"35.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Thymic epithelial cells":"71.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"3.7"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"18.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"6.5","prostate cancer":"7.3","thyroid cancer":"1.9"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enteroendocrine cells","Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 1","Pancreas - Alpha cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054814","HPA070485"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA054814":"AB_2682611","HPA070485":"AB_2686272"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"SERTM2","Gene synonym":["LINC00890"],"Ensembl":"ENSG00000260802","Gene description":"Serine rich and transmembrane domain containing 2","Uniprot":["A0A1B0GWG4"],"Chromosome":"X","Position":"111511662-111522399","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"27.3","epididymis":"41.9","seminal vesicle":"75.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"2.5","Muller glia cells":"1.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"2.9","renal cancer":"1.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Neuroblastoma":"7.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"2.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-3"}},{"Gene":"SETD4","Gene synonym":["C21orf18","C21orf27"],"Ensembl":"ENSG00000185917","Gene description":"SET domain containing 4","Uniprot":["Q9NVD3"],"Chromosome":"21","Position":"36034541-36079389","Protein class":["Predicted intracellular proteins"],"Biological process":["Inflammatory response"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"73.2","Spermatocytes":"57.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024073","HPA035405"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA024073":"AB_1856755","HPA035405":"AB_2674612"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"}},{"Gene":"SETDB1","Gene synonym":["ESET","KG1T","KIAA0067","KMT1E","TDRD21"],"Ensembl":"ENSG00000143379","Gene description":"SET domain bifurcated histone lysine methyltransferase 1","Uniprot":["Q15047"],"Chromosome":"1","Position":"150926263-150964744","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018142","HPA058484"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA018142":"AB_1856757","HPA058484":"AB_2683731"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.88e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"}},{"Gene":"SEZ6","Gene synonym":[],"Ensembl":"ENSG00000063015","Gene description":"Seizure related 6 homolog","Uniprot":["Q53EL9"],"Chromosome":"17","Position":"28954901-29006440","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"54.7","pituitary gland":"15.8","retina":"27.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"61.6","Cone photoreceptor cells":"22.4","Excitatory neurons":"15.6","Horizontal cells":"70.5","Inhibitory neurons":"23.8","Rod photoreceptor cells":"21.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"16.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"1.1","neutrophil":"2.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"12.4","Neuroblastoma":"13.4","thyroid cancer":"20.3"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011777"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"310000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011777":"AB_1856758"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"}},{"Gene":"SEZ6L","Gene synonym":[],"Ensembl":"ENSG00000100095","Gene description":"Seizure related 6 homolog like","Uniprot":["Q9BYH1"],"Chromosome":"22","Position":"26169462-26383597","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"60.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"218.7","Inhibitory neurons":"134.3","Oligodendrocyte precursor cells":"561.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"14.6","pancreatic cancer":"3.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"intermediate monocyte":"5.9","myeloid DC":"5.7","non-classical monocyte":"5.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"58","RNA blood lineage specific nTPM":{"dendritic cells":"5.7","monocytes":"5.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"25.6","lung cancer":"7.0","Neuroblastoma":"22.1"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Heart muscle - Fibroblasts","Pancreas - Alpha cells","Pancreas - Beta cells","Skin - Outer root sheath cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045135"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6700000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA045135":"AB_2732518"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"}},{"Gene":"SEZ6L2","Gene synonym":["FLJ90517","PSK-1"],"Ensembl":"ENSG00000174938","Gene description":"Seizure related 6 homolog like 2","Uniprot":["Q6UXD5"],"Chromosome":"16","Position":"29871159-29899547","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"101.6","pituitary gland":"91.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"233.2","Cone photoreceptor cells":"217.1","Horizontal cells":"254.4","Rod photoreceptor cells":"255.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enteroendocrine cells","Liver - Cholangiocyte","Prostate - Prostate glandular cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064471"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5600000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064471":"AB_2685271"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.46e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.31e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.24e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"}},{"Gene":"SF3B1","Gene synonym":["Hsh155","Prp10","PRPF10","SAP155","SF3b155"],"Ensembl":"ENSG00000115524","Gene description":"Splicing factor 3b subunit 1","Uniprot":["O75533"],"Chromosome":"2","Position":"197388515-197435079","Protein class":["Cancer-related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["RNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050275"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"94000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA050275":"AB_2681071"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"}},{"Gene":"SFT2D1","Gene synonym":["C6orf83","MGC19825","pRGR1"],"Ensembl":"ENSG00000198818","Gene description":"SFT2 domain containing 1","Uniprot":["Q8WV19"],"Chromosome":"6","Position":"166319728-166342576","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014677"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA014677":"AB_2238986"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.47e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.19e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.90e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"}},{"Gene":"SFT2D2","Gene synonym":["dJ747L4.C1.2","UNQ512"],"Ensembl":"ENSG00000213064","Gene description":"SFT2 domain containing 2","Uniprot":["O95562"],"Chromosome":"1","Position":"168225938-168253021","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"214.4","Late spermatids":"147.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"53.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042207"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042207":"AB_10794789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"}},{"Gene":"SFT2D3","Gene synonym":["MGC5391"],"Ensembl":"ENSG00000173349","Gene description":"SFT2 domain containing 3","Uniprot":["Q587I9"],"Chromosome":"2","Position":"127701497-127705242","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SFTPC","Gene synonym":["BRICD6","PSP-C","SFTP2","SMDP2","SP-C"],"Ensembl":"ENSG00000168484","Gene description":"Surfactant protein C","Uniprot":["P11686"],"Chromosome":"8","Position":"22156913-22164479","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Gaseous exchange"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"795","RNA tissue specific nTPM":{"lung":"18462.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"26","RNA single cell type specific nTPM":{"Alveolar cells type 2":"95842.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"218","RNA cancer specific FPKM":{"lung cancer":"226.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Sarcoma":"1.7","skin cancer":"1.3"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010928"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010928":"AB_1857425"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"SFXN1","Gene synonym":["FLJ12876","SLC56A1"],"Ensembl":"ENSG00000164466","Gene description":"Sideroflexin 1","Uniprot":["Q9H9B4"],"Chromosome":"5","Position":"175477062-175529742","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","One-carbon metabolism","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"99.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"99.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"99.8","T-cells":"36.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019543","HPA063745"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA019543":"AB_1856789","HPA063745":"AB_2685111"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"}},{"Gene":"SFXN2","Gene synonym":["SLC56A2"],"Ensembl":"ENSG00000156398","Gene description":"Sideroflexin 2","Uniprot":["Q96NB2"],"Chromosome":"10","Position":"102714538-102743492","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"17.9","parathyroid gland":"12.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"21.4","Proximal tubular cells":"26.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018150","HPA026834"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA018150":"AB_1856790","HPA026834":"AB_1856791"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.28e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.95e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.28e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.52e-4"}},{"Gene":"SFXN3","Gene synonym":["SFX3","SLC56A3"],"Ensembl":"ENSG00000107819","Gene description":"Sideroflexin 3","Uniprot":["Q9BWM7"],"Chromosome":"10","Position":"101031234-101041244","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Amino-acid transport","One-carbon metabolism","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"192.3","Proximal enterocytes":"108.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008028","HPA048105"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA008028":"AB_1079938","HPA048105":"AB_2680265"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.79e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.94e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"}},{"Gene":"SFXN4","Gene synonym":["SLC56A4"],"Ensembl":"ENSG00000183605","Gene description":"Sideroflexin 4","Uniprot":["Q6P4A7"],"Chromosome":"10","Position":"119140767-119165714","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018028","HPA020872"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA018028":"AB_1856792","HPA020872":"AB_1856793"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"}},{"Gene":"SFXN5","Gene synonym":["BBG-TCC","SLC56A5"],"Ensembl":"ENSG00000144040","Gene description":"Sideroflexin 5","Uniprot":["Q8TD22"],"Chromosome":"2","Position":"72942036-73075619","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"63.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"392.5","Late spermatids":"191.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"13.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015473","HPA056866"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA015473":"AB_1856794","HPA056866":"AB_2683261"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.26e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"}},{"Gene":"SGCA","Gene synonym":["A2","adhalin","ADL","DMDA2","LGMD2D","SCARMD1"],"Ensembl":"ENSG00000108823","Gene description":"Sarcoglycan alpha","Uniprot":["Q16586"],"Chromosome":"17","Position":"50164214-50175928","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"heart muscle":"155.6","skeletal muscle":"522.4","tongue":"237.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"681.9","Skeletal myocytes":"253.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"4.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"intermediate monocyte":"1.4","memory B-cell":"3.3","myeloid DC":"2.2","naive B-cell":"3.3","non-classical monocyte":"1.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"B-cells":"3.3","dendritic cells":"2.2","monocytes":"1.8"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"Sarcoma":"28.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Heart muscle - Cardiomyocytes","Liver - Hepatic stellate cells","Prostate - Smooth muscle cells","Skin - Fibroblast_2","Testis - Late spermatids","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007537"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007537":"AB_1079944"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"}},{"Gene":"SGCB","Gene synonym":["A3b","LGMD2E","SGC"],"Ensembl":"ENSG00000163069","Gene description":"Sarcoglycan beta","Uniprot":["Q16585"],"Chromosome":"4","Position":"52020706-52038299","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"105.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"134.5","Late spermatids":"202.5","Skeletal myocytes":"116.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"56.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011422","HPA058656"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA011422":"AB_1856795","HPA058656":"AB_2683790"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.53e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.61e-4"}},{"Gene":"SGCD","Gene synonym":["CMD1L","DAGD","LGMD2F"],"Ensembl":"ENSG00000170624","Gene description":"Sarcoglycan delta","Uniprot":["Q92629"],"Chromosome":"5","Position":"155870344-156767788","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"39.1","skeletal muscle":"42.9","tongue":"33.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"354.3","Cardiomyocytes":"142.1","Excitatory neurons":"190.3","Inhibitory neurons":"157.2","Microglial cells":"121.3","Oligodendrocyte precursor cells":"399.5","Oligodendrocytes":"185.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"melanoma":"10.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"10.9"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Pancreas - Fibroblasts","Prostate - Fibroblasts","Skin - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"}},{"Gene":"SGCE","Gene synonym":["DYT11"],"Ensembl":"ENSG00000127990","Gene description":"Sarcoglycan epsilon","Uniprot":["O43556"],"Chromosome":"7","Position":"94524204-94656572","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"127.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"gdT-cell":"2.1","memory B-cell":"4.4","naive B-cell":"6.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"6.6","T-cells":"2.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074790"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Golgi apparatus"],"Antibody RRID":{"HPA074790":"AB_2686713"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"}},{"Gene":"SGCG","Gene synonym":["A4","DAGA4","DMDA","DMDA1","LGMD2C","MAM","MGC130048","SCARMD2","SCG3","TYPE"],"Ensembl":"ENSG00000102683","Gene description":"Sarcoglycan gamma","Uniprot":["Q13326"],"Chromosome":"13","Position":"23180979-23325162","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"heart muscle":"118.8","skeletal muscle":"158.0","tongue":"144.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Cardiomyocytes":"167.9","Skeletal myocytes":"79.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"1.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"3.0","Rhabdoid":"6.5"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Stomach - Fibroblasts","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007476"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007476":"AB_1079946"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"SGCZ","Gene synonym":["ZSG1"],"Ensembl":"ENSG00000185053","Gene description":"Sarcoglycan zeta","Uniprot":["Q96LD1"],"Chromosome":"8","Position":"14084845-15238431","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"2.3","ovary":"1.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"468.8","Inhibitory neurons":"2246.5","Oligodendrocyte precursor cells":"1182.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"1.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017585"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017585":"AB_1856799"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SGMS1","Gene synonym":["MGC17342","MOB","SMS1","TMEM23"],"Ensembl":"ENSG00000198964","Gene description":"Sphingomyelin synthase 1","Uniprot":["Q86VZ5"],"Chromosome":"10","Position":"50305586-50625163","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"150.9","Microglial cells":"223.5","Oligodendrocyte precursor cells":"299.9","Oligodendrocytes":"398.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skin - Keratinocyte (other)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045191"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center","Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA045191":"AB_10959605"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.95e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"}},{"Gene":"SGMS2","Gene synonym":["MGC26963","SMS2"],"Ensembl":"ENSG00000164023","Gene description":"Sphingomyelin synthase 2","Uniprot":["Q8NHU3"],"Chromosome":"4","Position":"107824563-107915047","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"116.5","Alveolar cells type 2":"122.6","Endometrial ciliated cells":"167.6","Glandular and luminal cells":"132.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"classical monocyte":"3.7","eosinophil":"2.4","intermediate monocyte":"1.5","myeloid DC":"4.2","non-classical monocyte":"1.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"35","RNA blood lineage specific nTPM":{"dendritic cells":"4.2","granulocytes":"2.4","monocytes":"3.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Pancreas - Ductal cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015076","HPA015541"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA015076":"AB_1857298","HPA015541":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.37e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-3"}},{"Gene":"SGPL1","Gene synonym":["SPL"],"Ensembl":"ENSG00000166224","Gene description":"Sphingosine-1-phosphate lyase 1","Uniprot":["O95470"],"Chromosome":"10","Position":"70815948-70881184","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021125","HPA023086"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA021125":"AB_1856803","HPA023086":"AB_1856804"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-3"}},{"Gene":"SGPP1","Gene synonym":[],"Ensembl":"ENSG00000126821","Gene description":"Sphingosine-1-phosphate phosphatase 1","Uniprot":["Q9BX95"],"Chromosome":"14","Position":"63684216-63728065","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"56.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"6.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053149","HPA064908"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053149":"AB_2682057","HPA064908":"AB_2797270"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"}},{"Gene":"SGPP2","Gene synonym":["FLJ39004","SPP2"],"Ensembl":"ENSG00000163082","Gene description":"Sphingosine-1-phosphate phosphatase 2","Uniprot":["Q8IWX5"],"Chromosome":"2","Position":"222424543-222562621","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"85.9","Glandular and luminal cells":"110.5","Suprabasal keratinocytes":"78.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 2","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.28e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"}},{"Gene":"SGTA","Gene synonym":["SGT"],"Ensembl":"ENSG00000104969","Gene description":"Small glutamine rich tetratricopeptide repeat containing alpha","Uniprot":["O43765"],"Chromosome":"19","Position":"2754715-2783362","Protein class":["Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056309"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"81000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA056309":"AB_2683096"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.70e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"}},{"Gene":"SH2D3A","Gene synonym":["NSP1"],"Ensembl":"ENSG00000125731","Gene description":"SH2 domain containing 3A","Uniprot":["Q9BRG2"],"Chromosome":"19","Position":"6752160-6767463","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"32.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ionocytes":"66.9","Paneth cells":"68.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate basal glandular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035722","HPA064382"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Microtubules","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Microtubules"],"Subcellular additional location":["Nucleoplasm","Cytokinetic bridge"],"Antibody RRID":{"HPA035722":"AB_10670024","HPA064382":"AB_2685251"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.21e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-3"}},{"Gene":"SH3GLB1","Gene synonym":["Bif-1","CGI-61","KIAA0491","PPP1R70"],"Ensembl":"ENSG00000097033","Gene description":"SH3 domain containing GRB2 like, endophilin B1","Uniprot":["Q9Y371"],"Chromosome":"1","Position":"86704570-86748184","Protein class":["Metabolic proteins","Predicted intracellular proteins","Transporters"],"Biological process":["Apoptosis","Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"691.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"301.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004650","HPA015608","HPA019900"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004650":"AB_425966","HPA015608":"AB_1845355","HPA019900":"AB_1845356"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.90e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"}},{"Gene":"SH3GLB2","Gene synonym":["KIAA1848"],"Ensembl":"ENSG00000148341","Gene description":"SH3 domain containing GRB2 like, endophilin B2","Uniprot":["Q9NR46"],"Chromosome":"9","Position":"129007036-129028331","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"126.4","Syncytiotrophoblasts":"167.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021438","HPA024734"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA021438":"AB_1856820","HPA024734":"AB_1856821"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.56e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.28e-4"}},{"Gene":"SH3TC1","Gene synonym":["FLJ20356"],"Ensembl":"ENSG00000125089","Gene description":"SH3 domain and tetratricopeptide repeats 1","Uniprot":["Q8TE82"],"Chromosome":"4","Position":"8182072-8241803","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"28.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"69.3","Kupffer cells":"38.2","Macrophages":"37.1","monocytes":"72.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"17.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"6.8","dendritic cells":"17.7","monocytes":"12.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038132","HPA056807"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA038132":"AB_10673041","HPA056807":"AB_2683239"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"}},{"Gene":"SHISA2","Gene synonym":["bA398O19.2","C13orf13","hShisa","PRO28631","TMEM46","WGAR9166"],"Ensembl":"ENSG00000180730","Gene description":"Shisa family member 2","Uniprot":["Q6UWI4"],"Chromosome":"13","Position":"26044597-26052016","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"12.4","skeletal muscle":"14.2","thyroid gland":"21.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"19.6","Breast glandular cells":"19.4","granulocytes":"95.2","Skeletal myocytes":"24.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"25.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Podocytes","Skin - Outer root sheath cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049752","HPA050172"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Vesicles"],"Antibody RRID":{"HPA049752":null,"HPA050172":"AB_2681041"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.30e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.43e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"}},{"Gene":"SHISA3","Gene synonym":["hShisa3"],"Ensembl":"ENSG00000178343","Gene description":"Shisa family member 3","Uniprot":["A0PJX4"],"Chromosome":"4","Position":"42397488-42402487","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"13.3","heart muscle":"15.5","kidney":"21.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"6.2","Endothelial cells":"4.5","Fibroblasts":"20.8","Smooth muscle cells":"5.1","Thymic epithelial cells":"17.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"7.6","renal cancer":"7.8"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"midbrain":"13.3","thalamus":"10.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Bladder cancer":"17.6","Neuroblastoma":"17.1","ovarian cancer":"14.6","prostate cancer":"11.7","Sarcoma":"20.4","testis cancer":"8.1","Uterine cancer":"12.2"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Fibroblasts","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"23","RNA mouse brain regional specific nTPM":{"olfactory bulb":"51.7"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"spinal cord":"21.4"},"Antibody":["HPA054754"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Lipid droplets","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Lipid droplets"],"Antibody RRID":{"HPA054754":"AB_2682593"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-3"}},{"Gene":"SHISA4","Gene synonym":["C1orf40","hShisa4","TMEM58"],"Ensembl":"ENSG00000198892","Gene description":"Shisa family member 4","Uniprot":["Q96DD7"],"Chromosome":"1","Position":"201888680-201892587","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"71.6","skeletal muscle":"219.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"43.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"49.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"eosinophil":"24.6","intermediate monocyte":"8.1","neutrophil":"9.1","non-classical monocyte":"10.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"24.6","monocytes":"10.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Skin - Fibroblast_2","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061273","HPA067885"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA061273":"AB_2684460","HPA067885":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"}},{"Gene":"SHISA5","Gene synonym":["hShisa5","SCOTIN"],"Ensembl":"ENSG00000164054","Gene description":"Shisa family member 5","Uniprot":["Q8N114"],"Chromosome":"3","Position":"48467798-48504826","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"295.3","Extravillous trophoblasts":"229.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042295"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042295":"AB_10794794"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.72e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.64e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"}},{"Gene":"SHISA6","Gene synonym":["FLJ45455"],"Ensembl":"ENSG00000188803","Gene description":"Shisa family member 6","Uniprot":["Q6ZSJ9"],"Chromosome":"17","Position":"11241213-11564063","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"46.2","cervix":"16.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"48.7","Excitatory neurons":"27.1","Inhibitory neurons":"176.8","Oligodendrocyte precursor cells":"74.1","Peritubular cells":"30.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"7.0"},"RNA tissue cell type enrichment":["Colon - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023440"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA023440":"AB_1848945"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.41e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"}},{"Gene":"SHISA8","Gene synonym":["C22orf17","Orf26"],"Ensembl":"ENSG00000234965","Gene description":"Shisa family member 8","Uniprot":["B8ZZ34"],"Chromosome":"22","Position":"41909554-41914667","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"adrenal gland":"13.8","brain":"51.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Horizontal cells":"139.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"9","RNA brain regional specific nTPM":{"cerebellum":"51.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"cerebellum":"7.8","olfactory bulb":"15.7","white matter":"4.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059173"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059173":"AB_2683938"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"}},{"Gene":"SHISA9","Gene synonym":[],"Ensembl":"ENSG00000237515","Gene description":"Shisa family member 9","Uniprot":["B4DS77"],"Chromosome":"16","Position":"12901598-13240416","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Excitatory neurons":"261.0","Inhibitory neurons":"419.2","Oligodendrocyte precursor cells":"609.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"22.2"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072399"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA072399":"AB_2686517"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.53e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"}},{"Gene":"SHISAL1","Gene synonym":["KIAA1644"],"Ensembl":"ENSG00000138944","Gene description":"Shisa like 1","Uniprot":["Q3SXP7"],"Chromosome":"22","Position":"44243665-44312951","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"43.2","endometrium 1":"33.6","smooth muscle":"29.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"6.5","Endometrial stromal cells":"4.3","Excitatory neurons":"5.8","granulocytes":"4.9","Horizontal cells":"3.2","Inhibitory neurons":"11.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"14.0"},"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051178"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA051178":"AB_2681374"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-4"}},{"Gene":"SHISAL2A","Gene synonym":["FAM159A","MGC52498"],"Ensembl":"ENSG00000182183","Gene description":"Shisa like 2A","Uniprot":["Q6UWV7"],"Chromosome":"1","Position":"52633168-52669683","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.7","intestine":"3.7","lymphoid tissue":"5.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"33.5","NK-cells":"20.2","Plasma cells":"9.2","T-cells":"20.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hypothalamus":"8.7"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"10.1","NK-cells":"5.9","T-cells":"7.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Leukemia":"1.3","lymphoma":"3.3","Myeloma":"4.2"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Liver - T-cells","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"4.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030744"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030744":"AB_10963060"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"}},{"Gene":"SHISAL2B","Gene synonym":["FAM159B"],"Ensembl":"ENSG00000145642","Gene description":"Shisa like 2B","Uniprot":["A6NKW6"],"Chromosome":"5","Position":"64690442-64718190","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"3.0","pancreas":"4.9","stomach 1":"2.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Pancreatic endocrine cells":"27.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"pancreatic cancer":"3.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hypothalamus":"3.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"17","RNA cell line specific nTPM":{"Rhabdoid":"6.5"},"RNA tissue cell type enrichment":["Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011778"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011778":"AB_1848382"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"}},{"Gene":"SHLD2","Gene synonym":["bA163M19.1","FAM35A","FAM35A1","MGC5560","RINN2"],"Ensembl":"ENSG00000122376","Gene description":"Shieldin complex subunit 2","Uniprot":["Q86V20"],"Chromosome":"10","Position":"87094161-87191465","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036582","HPA057506"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA036582":"AB_10670233","HPA057506":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.06e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.09e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"}},{"Gene":"SHOC1","Gene synonym":["C9orf84","FLJ32779","MZIP2","Zip2"],"Ensembl":"ENSG00000165181","Gene description":"Shortage in chiasmata 1","Uniprot":["Q5VXU9"],"Chromosome":"9","Position":"111686173-111795008","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Meiosis"],"Molecular function":["DNA-binding","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"testis":"17.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"128.9","Microglial cells":"24.6","Oligodendrocyte precursor cells":"31.8","Spermatocytes":"96.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"neutrophil":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"1.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"5.8"},"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032108"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA032108":"AB_10669884"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"}},{"Gene":"SI","Gene synonym":[],"Ensembl":"ENSG00000090402","Gene description":"Sucrase-isomaltase","Uniprot":["P14410"],"Chromosome":"3","Position":"164978898-165078496","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase","Multifunctional enzyme"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"150","RNA tissue specific nTPM":{"intestine":"545.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Proximal enterocytes":"1131.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"6.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.5","prostate cancer":"1.8"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011897"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 26: NCI-H716 - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011897":"AB_1856840"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SIDT1","Gene synonym":["FLJ20174","SID-1"],"Ensembl":"ENSG00000072858","Gene description":"SID1 transmembrane family member 1","Uniprot":["Q9NXL6"],"Chromosome":"3","Position":"113532555-113629575","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"10.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"42.4","dendritic cells":"165.5","Excitatory neurons":"116.2","Inhibitory neurons":"84.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"5.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"33.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"6.9","Myeloma":"7.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035862"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035862":"AB_10671110"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.78e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.09e-5"}},{"Gene":"SIDT2","Gene synonym":["CGI-40"],"Ensembl":"ENSG00000149577","Gene description":"SID1 transmembrane family member 2","Uniprot":["Q8NBJ9"],"Chromosome":"11","Position":"117178736-117197445","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["DNA-binding","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"101.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"intermediate monocyte":"83.5","non-classical monocyte":"151.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"monocytes":"151.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052352"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052352":"AB_2681797"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.18e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-3"}},{"Gene":"SIGIRR","Gene synonym":["IL-1R8","TIR8"],"Ensembl":"ENSG00000185187","Gene description":"Single Ig and TIR domain containing","Uniprot":["Q6IA17"],"Chromosome":"11","Position":"405716-417455","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"433.1","Proximal tubular cells":"612.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023188"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Nucleoli fibrillar center","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023188":"AB_1856856"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.44e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.34e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.08e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.61e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.54e-5"}},{"Gene":"SIGLEC1","Gene synonym":["CD169","dJ1009E24.1","FLJ00051","FLJ00055","FLJ00073","FLJ32150","sialoadhesin","SIGLEC-1","SN"],"Ensembl":"ENSG00000088827","Gene description":"Sialic acid binding Ig like lectin 1","Uniprot":["Q9BZZ2"],"Chromosome":"20","Position":"3686970-3712600","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Endocytosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hofbauer cells":"77.2","Macrophages":"55.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.5"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"monocytes":"1.5"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053457"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053457":"AB_2682158"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.69e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.36e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"}},{"Gene":"SIGLEC10","Gene synonym":["MGC126774","PRO940","SIGLEC-10","SLG2"],"Ensembl":"ENSG00000142512","Gene description":"Sialic acid binding Ig like lectin 10","Uniprot":["Q96LC7"],"Chromosome":"19","Position":"51410020-51417803","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Cell adhesion","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"38.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"32.3","Kupffer cells":"75.6","Macrophages":"62.9","monocytes":"132.9","Schwann cells":"25.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"11.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"eosinophil":"765.3","intermediate monocyte":"252.0","non-classical monocyte":"539.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"granulocytes":"765.3","monocytes":"539.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"9.9","lymphoma":"31.8"},"RNA tissue cell type enrichment":["Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025807","HPA027093"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Actin filaments","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane","Actin filaments"],"Antibody RRID":{"CAB025807":null,"HPA027093":"AB_1856858"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.74e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"}},{"Gene":"SIGLEC11","Gene synonym":[],"Ensembl":"ENSG00000161640","Gene description":"Sialic acid binding Ig like lectin 11","Uniprot":["Q96RL6"],"Chromosome":"19","Position":"49948985-49961172","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"23.1","ovary":"65.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Granulosa cells":"159.5","Theca cells":"117.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1.4","non-classical monocyte":"1.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"1.4","monocytes":"1.3"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Liver - Kupffer cells","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Parietal cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052132","HPA060278"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA052132":null,"HPA060278":"AB_2684240"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"}},{"Gene":"SIGLEC12","Gene synonym":["S2V","Siglec-12","Siglec-L1","Siglec-XII","SIGLECL1","SLG"],"Ensembl":"ENSG00000254521","Gene description":"Sialic acid binding Ig like lectin 12","Uniprot":["Q96PQ1"],"Chromosome":"19","Position":"51491227-51501800","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"6.1","lymphoid tissue":"14.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"granulocytes":"1.8","Hofbauer cells":"3.4","Kupffer cells":"2.9","Macrophages":"3.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"28","RNA cell line specific nTPM":{"Leukemia":"17.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"}},{"Gene":"SIGLEC14","Gene synonym":[],"Ensembl":"ENSG00000254415","Gene description":"Sialic acid binding Ig like lectin 14","Uniprot":["Q08ET2"],"Chromosome":"19","Position":"51642553-51646801","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"28.3","lymphoid tissue":"40.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hofbauer cells":"23.6","Kupffer cells":"47.9","Macrophages":"20.3","monocytes":"27.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"109.1","intermediate monocyte":"125.1","myeloid DC":"65.4","neutrophil":"200.1","non-classical monocyte":"93.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"65.4","granulocytes":"200.1","monocytes":"125.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"4.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Colon - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014377","HPA014428"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA014377":"AB_2189277","HPA014428":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"}},{"Gene":"SIGLEC15","Gene synonym":["CD33L3","HsT1361"],"Ensembl":"ENSG00000197046","Gene description":"Sialic acid binding Ig like lectin 15","Uniprot":["Q6ZMC9"],"Chromosome":"18","Position":"45825675-45844094","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"1.7","intestine":"3.0","urinary bladder":"1.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"2.7","Cholangiocytes":"1.9","Hofbauer cells":"9.3","Langerhans cells":"2.7","Macrophages":"3.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"3.0","myeloid DC":"1.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"dendritic cells":"1.0","monocytes":"3.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"10.6","thyroid cancer":"12.5"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053509"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA053509":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.14e-5"}},{"Gene":"SIGLEC5","Gene synonym":["CD170","CD33L2","OB-BP2","SIGLEC-5"],"Ensembl":"ENSG00000105501","Gene description":"Sialic acid binding Ig like lectin 5","Uniprot":["O15389"],"Chromosome":"19","Position":"51611927-51645545","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"14.7","lymphoid tissue":"12.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"5.4","Kupffer cells":"10.7","Macrophages":"3.6","monocytes":"3.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"urothelial cancer":"1.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"152.5","non-classical monocyte":"49.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"152.5","monocytes":"49.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"3.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009085","CAB024900"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB024900":null,"HPA009085":"AB_1079965"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"}},{"Gene":"SIGLEC6","Gene synonym":["CD327","CD33L","CD33L1","OB-BP1","SIGLEC-6"],"Ensembl":"ENSG00000105492","Gene description":"Sialic acid binding Ig like lectin 6","Uniprot":["O43699"],"Chromosome":"19","Position":"51517819-51531856","Protein class":["CD markers","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"placenta":"106.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Cytotrophoblasts":"174.7","granulocytes":"171.4","Syncytiotrophoblasts":"326.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"2.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"4.9","memory B-cell":"7.2","naive B-cell":"4.5","plasmacytoid DC":"11.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"B-cells":"7.2","dendritic cells":"11.0","granulocytes":"4.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"Bladder cancer":"7.9","colorectal cancer":"16.1","Leukemia":"25.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Adipose visceral - Mast cells","Colon - Mast cells","Lung - Mast cells","Skin - Mast cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008945","HPA009084","HPA018198"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008945":null,"HPA009084":"AB_1079967","HPA018198":"AB_1856868"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-3"}},{"Gene":"SIGLEC7","Gene synonym":["CD328","p75\/AIRM1","QA79","SIGLEC-7","SIGLEC19P","SIGLECP2"],"Ensembl":"ENSG00000168995","Gene description":"Sialic acid binding Ig like lectin 7","Uniprot":["Q9Y286"],"Chromosome":"19","Position":"51142299-51153526","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"19.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hofbauer cells":"36.7","Kupffer cells":"39.7","Macrophages":"33.3","monocytes":"16.7","NK-cells":"39.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"242.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"Leukemia":"4.0","Myeloma":"5.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075513"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2600000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA075513":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"}},{"Gene":"SIGLEC8","Gene synonym":["MGC59785","SAF2","SIGLEC-8","SIGLEC8L"],"Ensembl":"ENSG00000105366","Gene description":"Sialic acid binding Ig like lectin 8","Uniprot":["Q9NYZ4"],"Chromosome":"19","Position":"51450847-51458456","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.9","lymphoid tissue":"6.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"granulocytes":"30.0","Macrophages":"11.2","Microglial cells":"10.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"7.2","renal cancer":"2.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"38","RNA blood cell specific nTPM":{"eosinophil":"290.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"719","RNA blood lineage specific nTPM":{"granulocytes":"290.2"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"2.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Colon - Mast cells","Pancreas - Macrophages","Skin - Mast cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012556"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA012556":"AB_1856869"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"}},{"Gene":"SIGLEC9","Gene synonym":["CD329"],"Ensembl":"ENSG00000129450","Gene description":"Sialic acid binding Ig like lectin 9","Uniprot":["Q9Y336"],"Chromosome":"19","Position":"51124906-51136651","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"20.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hofbauer cells":"43.6","Kupffer cells":"23.6","Langerhans cells":"20.0","Macrophages":"25.5","monocytes":"18.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"classical monocyte":"198.9","intermediate monocyte":"182.5","myeloid DC":"169.1","neutrophil":"212.0","non-classical monocyte":"121.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"dendritic cells":"169.1","granulocytes":"212.0","monocytes":"198.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"1.9","Myeloma":"3.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010682"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010682":"AB_1079968"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"}},{"Gene":"SIGLECL1","Gene synonym":["C19orf75","FLJ40235","SIGLEC23P","SIGLECP7"],"Ensembl":"ENSG00000179213","Gene description":"SIGLEC family like 1","Uniprot":["Q8N7X8"],"Chromosome":"19","Position":"51246348-51269330","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"73","RNA tissue specific nTPM":{"testis":"22.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"57.5","Late spermatids":"68.2","Spermatocytes":"63.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Kidney cancer":"1.0","lymphoma":"2.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079471"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA079471":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SIGMAR1","Gene synonym":["OPRS1","SR-BP1"],"Ensembl":"ENSG00000147955","Gene description":"Sigma non-opioid intracellular receptor 1","Uniprot":["Q99720"],"Chromosome":"9","Position":"34634722-34637844","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"187.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"101.5","Hepatocytes":"86.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013470","HPA018002","HPA024071"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013470":"AB_2533521","HPA018002":"AB_1854802","HPA024071":"AB_1854803"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.42e-4"}},{"Gene":"SIK1","Gene synonym":["msk","SNF1LK"],"Ensembl":"ENSG00000142178","Gene description":"Salt inducible kinase 1","Uniprot":["P57059"],"Chromosome":"21","Position":"43414483-43427131","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Biological rhythms","Cell cycle","Differentiation"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"88.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"9.8","Collecting duct cells":"11.8","Glandular and luminal cells":"8.6","Suprabasal keratinocytes":"21.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"29.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB023801","HPA038211","HPA078064"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB023801":null,"HPA038211":"AB_2675894","HPA078064":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"}},{"Gene":"SIK1B","Gene synonym":[],"Ensembl":"ENSG00000275993","Gene description":"Salt inducible kinase 1B (putative)","Uniprot":["A0A0B4J2F2"],"Chromosome":"21","Position":"6111131-6123778","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"243.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"72.8","Gastric mucus-secreting cells":"75.1","Plasma cells":"40.1","Squamous epithelial cells":"89.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"71.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038211","HPA078064"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA038211":"AB_2675894","HPA078064":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"}},{"Gene":"SIK2","Gene synonym":["DKFZp434K1115","KIAA0781","LOH11CR1I","QIK","SNF1LK2"],"Ensembl":"ENSG00000170145","Gene description":"Salt inducible kinase 2","Uniprot":["Q9H0K1"],"Chromosome":"11","Position":"111602449-111730855","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"109.8","Excitatory neurons":"214.5","Inhibitory neurons":"129.2","Oligodendrocytes":"181.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016026","HPA071049"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear speckles","Vesicles","Intermediate filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Nuclear speckles","Intermediate filaments","Cytosol"],"Antibody RRID":{"HPA016026":"AB_1857321","HPA071049":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.93e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.17e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"}},{"Gene":"SIK3","Gene synonym":["FLJ12240","KIAA0999","L19","QSK"],"Ensembl":"ENSG00000160584","Gene description":"SIK family kinase 3","Uniprot":["Q9Y2K2"],"Chromosome":"11","Position":"116843402-117098437","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"363.8","Excitatory neurons":"378.8","Inhibitory neurons":"390.6","Oligodendrocyte precursor cells":"438.5","Oligodendrocytes":"1585.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045245","HPA048161"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045245":"AB_2679270","HPA048161":"AB_2680293"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"}},{"Gene":"SIN3B","Gene synonym":["KIAA0700"],"Ensembl":"ENSG00000127511","Gene description":"SIN3 transcription regulator family member B","Uniprot":["O75182"],"Chromosome":"19","Position":"16829398-16880353","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"146.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050329"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA050329":"AB_2681089"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.37e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.58e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"SIRPA","Gene synonym":["BIT","CD172a","MFR","MYD-1","P84","PTPNS1","SHPS-1","SHPS1","SIRP","SIRP-ALPHA-1","SIRPalpha","SIRPalpha2"],"Ensembl":"ENSG00000198053","Gene description":"Signal regulatory protein alpha","Uniprot":["P78324"],"Chromosome":"20","Position":"1894167-1940592","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"157.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"133.8","Excitatory neurons":"86.1","Hofbauer cells":"101.6","Kupffer cells":"81.2","Macrophages":"88.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"24.1","eosinophil":"48.7","myeloid DC":"13.9","neutrophil":"50.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"150","RNA blood lineage specific nTPM":{"dendritic cells":"13.9","granulocytes":"50.8","monocytes":"24.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"107.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Testis - Spermatogonia"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002776","CAB015122","HPA054437","HPA058511"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002776":null,"CAB015122":"AB_677430","HPA054437":"AB_2682488","HPA058511":"AB_2683738"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"}},{"Gene":"SIRPB1","Gene synonym":["CD172b","SIRP-BETA-1"],"Ensembl":"ENSG00000101307","Gene description":"Signal regulatory protein beta 1","Uniprot":["O00241","Q5TFQ8"],"Chromosome":"20","Position":"1561385-1620061","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"52.2","lung":"19.4","lymphoid tissue":"28.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"dendritic cells":"36.0","Hofbauer cells":"29.7","Kupffer cells":"70.2","Macrophages":"32.0","monocytes":"48.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1594.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"1594.8","monocytes":"502.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"18.2","Sarcoma":"15.1","thyroid cancer":"22.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Liver - Neutrophils","Lung - Neutrophil_2"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047463"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA047463":"AB_2680057"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"}},{"Gene":"SIRPB2","Gene synonym":["dJ776F14.2","PTPN1L","PTPNS1L3"],"Ensembl":"ENSG00000196209","Gene description":"Signal regulatory protein beta 2","Uniprot":["Q5JXA9"],"Chromosome":"20","Position":"1470741-1491587","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"13.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"8.0","Kupffer cells":"17.3","Langerhans cells":"4.0","Macrophages":"11.8","Microglial cells":"13.7","monocytes":"7.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"classical monocyte":"51.1","eosinophil":"31.7","intermediate monocyte":"30.4","myeloid DC":"21.1","neutrophil":"69.5","non-classical monocyte":"24.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"329","RNA blood lineage specific nTPM":{"dendritic cells":"21.1","granulocytes":"69.5","monocytes":"51.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"5.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011548","HPA048032"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"250000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA011548":"AB_2668514","HPA048032":"AB_2680236"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"SIRPG","Gene synonym":["bA77C3.1","CD172g","SIRP-B2","SIRPB2","SIRPgamma"],"Ensembl":"ENSG00000089012","Gene description":"Signal regulatory protein gamma","Uniprot":["Q9P1W8"],"Chromosome":"20","Position":"1629152-1657779","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lymphoid tissue":"39.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"63.4","T-cells":"39.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"369.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"369.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"2.3","ovarian cancer":"2.2","thyroid cancer":"4.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Colon - T-cells","Kidney - T-cells","Liver - T-cells","Lung - T-cells","Pancreas - T-cells","Prostate - T-cells","Stomach - T-cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.24e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.36e-7"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.47e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"}},{"Gene":"SIT1","Gene synonym":["SIT"],"Ensembl":"ENSG00000137078","Gene description":"Signaling threshold regulating transmembrane adaptor 1","Uniprot":["Q9Y3P8"],"Chromosome":"9","Position":"35649295-35650950","Protein class":["Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lymphoid tissue":"95.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"B-cells":"80.9","dendritic cells":"39.5","Plasma cells":"23.8","T-cells":"80.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"46","RNA blood cell specific nTPM":{"gdT-cell":"119.1","MAIT T-cell":"202.7","memory B-cell":"213.6","memory CD4 T-cell":"249.2","memory CD8 T-cell":"223.4","naive B-cell":"192.1","naive CD4 T-cell":"170.4","naive CD8 T-cell":"169.5","plasmacytoid DC":"203.1","T-reg":"352.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"56","RNA blood lineage specific nTPM":{"B-cells":"213.6","dendritic cells":"203.1","T-cells":"352.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Leukemia":"22.7","lymphoma":"66.8"},"RNA tissue cell type enrichment":["Colon - T-cells","Lung - T-cells","Prostate - T-cells","Skin - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018506"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018506":"AB_2669896"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.56e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.94e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.17e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"}},{"Gene":"SIVA1","Gene synonym":["CD27BP","SIVA","Siva-1","Siva-2"],"Ensembl":"ENSG00000184990","Gene description":"SIVA1 apoptosis inducing factor","Uniprot":["O15304"],"Chromosome":"14","Position":"104753147-104768494","Protein class":["Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065398","HPA066693"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA065398":"AB_2685484","HPA066693":"AB_2685703"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.95e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"}},{"Gene":"SLAIN1","Gene synonym":["C13orf32","FLJ30046"],"Ensembl":"ENSG00000139737","Gene description":"SLAIN motif family member 1","Uniprot":["Q8ND83"],"Chromosome":"13","Position":"77697687-77764242","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"412.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Oligodendrocytes":"1021.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"25.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"60.3","Myeloma":"59.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Mesothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.07e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"}},{"Gene":"SLAMF1","Gene synonym":["CD150","SLAM"],"Ensembl":"ENSG00000117090","Gene description":"Signaling lymphocytic activation molecule family member 1","Uniprot":["Q13291"],"Chromosome":"1","Position":"160608106-160647295","Protein class":["CD markers","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Cell adhesion","Host-virus interaction","Immunity","Innate immunity","Phagocytosis"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"lymphoid tissue":"76.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"25.6","Langerhans cells":"10.1","Plasma cells":"41.1","T-cells":"38.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"66.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"B-cells":"22.7","T-cells":"66.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"13.5","lymphoma":"38.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Liver - T-cells","Prostate - T-cells","Skin - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002438","HPA069319"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"350000","Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002438":"AB_564011","HPA069319":"AB_2732129"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"}},{"Gene":"SLAMF6","Gene synonym":["CD352","KALI","KALIb","Ly108","NTB-A","NTBA","SF2000"],"Ensembl":"ENSG00000162739","Gene description":"SLAM family member 6","Uniprot":["Q96DU3"],"Chromosome":"1","Position":"160485030-160523262","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"61.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"B-cells":"22.0","Late spermatids":"23.2","NK-cells":"39.8","Plasma cells":"18.2","Serous glandular cells":"12.7","T-cells":"34.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"9.2","lymphoma":"34.1"},"RNA tissue cell type enrichment":["Breast - Plasma cells","Colon - T-cells","Liver - T-cells","Lung - T-cells","Prostate - T-cells","Stomach - T-cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051363","HPA051903"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA051363":"AB_2681454","HPA051903":"AB_2681658"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.42e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.78e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.53e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.34e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.09e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-3"}},{"Gene":"SLAMF7","Gene synonym":["19A","CD319","CRACC","CS1"],"Ensembl":"ENSG00000026751","Gene description":"SLAM family member 7","Uniprot":["Q9NQ25"],"Chromosome":"1","Position":"160739057-160754821","Protein class":["CD markers","FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"32.6","lymphoid tissue":"62.0","stomach 1":"34.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"80.9","monocytes":"44.3","NK-cells":"64.1","Plasma cells":"243.3","Schwann cells":"66.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Myeloma":"184.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Heart muscle - T-cells","Liver - T-cells","Lung - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015445","HPA055945","HPA061654"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB015445":"AB_1121905","HPA055945":"AB_2682980","HPA061654":"AB_2684576"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.57e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"}},{"Gene":"SLAMF8","Gene synonym":["BLAME","CD353","SBBI42"],"Ensembl":"ENSG00000158714","Gene description":"SLAM family member 8","Uniprot":["Q9P0V8"],"Chromosome":"1","Position":"159826811-159837492","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"32.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"34.9","Kupffer cells":"12.3","Langerhans cells":"69.9","Macrophages":"41.4","Schwann cells":"43.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"14.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.3","lymphoma":"2.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Heart muscle - Macrophages","Lung - Macrophages","Skeletal muscle - Fibroblasts","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067601"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA067601":"AB_2685870"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.42e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"SLAMF9","Gene synonym":["CD2F-10","CD84-H1","SF2001"],"Ensembl":"ENSG00000162723","Gene description":"SLAM family member 9","Uniprot":["Q96A28"],"Chromosome":"1","Position":"159951492-159954237","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Langerhans cells":"64.1","Late spermatids":"44.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"myeloid DC":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"2.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"skin cancer":"8.3"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035153"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035153":"AB_10670586"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"SLC10A1","Gene synonym":["NTCP"],"Ensembl":"ENSG00000100652","Gene description":"Solute carrier family 10 member 1","Uniprot":["Q14973"],"Chromosome":"14","Position":"69775416-69797241","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction","Ion transport","Sodium transport","Symport","Transport"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"164","RNA tissue specific nTPM":{"liver":"426.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"23","RNA single cell type specific nTPM":{"Hepatocytes":"136.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"79","RNA cancer specific FPKM":{"liver cancer":"65.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042727"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042727":"AB_10960691"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.53e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"}},{"Gene":"SLC10A2","Gene synonym":["ASBT","ISBT"],"Ensembl":"ENSG00000125255","Gene description":"Solute carrier family 10 member 2","Uniprot":["Q12908"],"Chromosome":"13","Position":"103043998-103066417","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"80.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Proximal enterocytes":"353.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"renal cancer":"4.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"1.6"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004795"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004795":"AB_1856953"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.78e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC10A3","Gene synonym":["DXS253E","P3"],"Ensembl":"ENSG00000126903","Gene description":"Solute carrier family 10 member 3","Uniprot":["P09131"],"Chromosome":"X","Position":"154487306-154490690","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"69.9","Syncytiotrophoblasts":"110.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"basophil":"218.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"granulocytes":"218.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021656"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA021656":"AB_1856955"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.53e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.15e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.97e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.22e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"}},{"Gene":"SLC10A4","Gene synonym":["MGC29802"],"Ensembl":"ENSG00000145248","Gene description":"Solute carrier family 10 member 4","Uniprot":["Q96EP9"],"Chromosome":"4","Position":"48483343-48489526","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"36.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"3.4","Early spermatids":"3.2","Erythroid cells":"2.7","Horizontal cells":"3.8","Inhibitory neurons":"15.7","Late spermatids":"4.9","Oligodendrocyte precursor cells":"3.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"endometrial cancer":"1.8","glioma":"5.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"36.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"Neuroblastoma":"46.7"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"26.2","hypothalamus":"10.7","midbrain":"26.5","pons and medulla":"13.2","thalamus":"8.4"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"basal ganglia":"14.2","midbrain":"56.7","pons":"23.5","spinal cord":"44.7"},"Antibody":["HPA028835"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA028835":"AB_10603025"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"}},{"Gene":"SLC10A5","Gene synonym":[],"Ensembl":"ENSG00000253598","Gene description":"Solute carrier family 10 member 5","Uniprot":["Q5PT55"],"Chromosome":"8","Position":"81693631-81695058","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"3.9","liver":"11.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"3.9","Gastric mucus-secreting cells":"7.2","Hepatocytes":"3.0","Intestinal goblet cells":"3.9","Ionocytes":"2.6","Paneth cells":"2.9","Proximal enterocytes":"6.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"2.9"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025966"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA025966":"AB_1856959"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-7"}},{"Gene":"SLC10A6","Gene synonym":["SOAT"],"Ensembl":"ENSG00000145283","Gene description":"Solute carrier family 10 member 6","Uniprot":["Q3KNW5"],"Chromosome":"4","Position":"86823468-86849384","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Lipid transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"9.1","skin 1":"13.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"194.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"cervical cancer":"3.5","head and neck cancer":"6.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"1.0"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016662"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016662":"AB_1669899"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-4"}},{"Gene":"SLC10A7","Gene synonym":["C4orf13","DKFZp313H0531","DKFZp566M114","DKFZp779O2438","MGC25043"],"Ensembl":"ENSG00000120519","Gene description":"Solute carrier family 10 member 7","Uniprot":["Q0GE19"],"Chromosome":"4","Position":"146253975-146521964","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"43.0","Microglial cells":"49.3","Oligodendrocyte precursor cells":"59.7","Oligodendrocytes":"77.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039996"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039996":"AB_10673266"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"}},{"Gene":"SLC11A1","Gene synonym":["LSH","NRAMP","NRAMP1"],"Ensembl":"ENSG00000018280","Gene description":"Solute carrier family 11 member 1","Uniprot":["P49279"],"Chromosome":"2","Position":"218382029-218396894","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Iron transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"78.6","lymphoid tissue":"46.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hofbauer cells":"174.3","Kupffer cells":"214.9","Macrophages":"206.8","monocytes":"313.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"7.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"classical monocyte":"6.1","intermediate monocyte":"4.5","myeloid DC":"1.9","neutrophil":"4.1","non-classical monocyte":"6.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"1.9","granulocytes":"4.1","monocytes":"6.1"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Colon - Neutrophils","Liver - Neutrophils","Prostate - Macrophages","Skin - Macrophages","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029590","HPA050378","HPA068540"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA029590":"AB_10794613","HPA050378":null,"HPA068540":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.58e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"}},{"Gene":"SLC11A2","Gene synonym":["DCT1","DMT1","NRAMP2"],"Ensembl":"ENSG00000110911","Gene description":"Solute carrier family 11 member 2","Uniprot":["P49281"],"Chromosome":"12","Position":"50979401-51028566","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Iron transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ionocytes":"114.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032139","HPA032140"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA032139":"AB_10964213","HPA032140":"AB_10962932"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.07e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"}},{"Gene":"SLC12A1","Gene synonym":["NKCC2"],"Ensembl":"ENSG00000074803","Gene description":"Solute carrier family 12 member 1","Uniprot":["Q13621"],"Chromosome":"15","Position":"48178438-48304078","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Bartter syndrome","Disease variant","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"878","RNA tissue specific nTPM":{"kidney":"705.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Collecting duct cells":"33.5","Distal tubular cells":"93.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"renal cancer":"1.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014967","HPA018107"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA014967":"AB_1854503","HPA018107":"AB_1854504"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"}},{"Gene":"SLC12A2","Gene synonym":["BSC","BSC2","NKCC1","PPP1R141"],"Ensembl":"ENSG00000064651","Gene description":"Solute carrier family 12 member 2","Uniprot":["P55011"],"Chromosome":"5","Position":"128083766-128189677","Protein class":["FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","FDA approved drug targets","Intellectual disability","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"75.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Intestinal goblet cells":"315.0","Oligodendrocytes":"534.9","Undifferentiated cells":"342.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"54.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"6.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"97.7"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Pancreas - Ductal cells","Skin - Eccrine sweat gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020130","HPA063697"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA020130":"AB_1854502","HPA063697":"AB_2685094"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.60e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"}},{"Gene":"SLC12A3","Gene synonym":["NCCT"],"Ensembl":"ENSG00000070915","Gene description":"Solute carrier family 12 member 3","Uniprot":["P55017"],"Chromosome":"16","Position":"56865207-56915850","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"101","RNA tissue specific nTPM":{"kidney":"101.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"5.9","dendritic cells":"21.1","Glandular and luminal cells":"4.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"2.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"20","RNA blood cell specific nTPM":{"plasmacytoid DC":"14.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"dendritic cells":"14.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"9.7","Uterine cancer":"6.7"},"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028748"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA028748":"AB_10603886"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"}},{"Gene":"SLC12A4","Gene synonym":["KCC1"],"Ensembl":"ENSG00000124067","Gene description":"Solute carrier family 12 member 4","Uniprot":["Q9UP95"],"Chromosome":"16","Position":"67943474-67969601","Protein class":["FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"40.1","Syncytiotrophoblasts":"63.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"7.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041138"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endosomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Endosomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA041138":"AB_10794544"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.25e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"}},{"Gene":"SLC12A5","Gene synonym":["KCC2","KIAA1176"],"Ensembl":"ENSG00000124140","Gene description":"Solute carrier family 12 member 5","Uniprot":["Q9H2X9"],"Chromosome":"20","Position":"46021690-46060150","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"145.8","retina":"117.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Bipolar cells":"212.2","Cone photoreceptor cells":"253.3","Excitatory neurons":"91.5","Horizontal cells":"132.0","Inhibitory neurons":"89.1","Rod photoreceptor cells":"195.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"2.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Alpha cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072058"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA072058":"AB_2686485"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.60e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"}},{"Gene":"SLC12A6","Gene synonym":["ACCPN","KCC3"],"Ensembl":"ENSG00000140199","Gene description":"Solute carrier family 12 member 6","Uniprot":["Q9UHW9"],"Chromosome":"15","Position":"34229784-34338060","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"74.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"15.2","neutrophil":"23.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"23.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034563"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA034563":"AB_10603887"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"}},{"Gene":"SLC12A7","Gene synonym":["DKFZP434F076","KCC4"],"Ensembl":"ENSG00000113504","Gene description":"Solute carrier family 12 member 7","Uniprot":["Q9Y666"],"Chromosome":"5","Position":"1050384-1112063","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"77.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"121.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Heart muscle - Cardiomyocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041652"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041652":"AB_10793971"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.12e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.16e-5"}},{"Gene":"SLC12A8","Gene synonym":["CCC9"],"Ensembl":"ENSG00000221955","Gene description":"Solute carrier family 12 member 8","Uniprot":["A0AV02"],"Chromosome":"3","Position":"125082636-125212864","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"22.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"23.6","Excitatory neurons":"37.9","Inhibitory neurons":"27.1","Intestinal goblet cells":"40.5","Oligodendrocyte precursor cells":"30.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Prostate - Prostate glandular cells","Skin - Outer root sheath cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031123"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA031123":"AB_2301872"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.56e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"}},{"Gene":"SLC12A9","Gene synonym":["CIP1"],"Ensembl":"ENSG00000146828","Gene description":"Solute carrier family 12 member 9","Uniprot":["Q9BXP2"],"Chromosome":"7","Position":"100826820-100867010","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"91.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067536"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA067536":"AB_2732768"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.97e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.00e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"}},{"Gene":"SLC13A1","Gene synonym":["NAS1","NaSi-1"],"Ensembl":"ENSG00000081800","Gene description":"Solute carrier family 13 member 1","Uniprot":["Q9BZW2"],"Chromosome":"7","Position":"123113531-123199972","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Sulfate transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"kidney":"81.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Proximal tubular cells":"431.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"219","RNA cancer specific FPKM":{"renal cancer":"10.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053615","HPA062714"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053615":"AB_2682207","HPA062714":"AB_2684846"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.95e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC13A2","Gene synonym":["NaDC-1"],"Ensembl":"ENSG00000007216","Gene description":"Solute carrier family 13 member 2","Uniprot":["Q13183"],"Chromosome":"17","Position":"28473293-28497781","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"119.6","kidney":"38.2","salivary gland":"44.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"266.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Pancreas - Ductal cells","Prostate - Urothelial cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014963"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014963":"AB_1857096"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.00e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"}},{"Gene":"SLC13A3","Gene synonym":["NADC3","SDCT2"],"Ensembl":"ENSG00000158296","Gene description":"Solute carrier family 13 member 3","Uniprot":["Q8WWT9"],"Chromosome":"20","Position":"46557823-46684467","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"kidney":"407.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"52.2","Cytotrophoblasts":"106.3","Excitatory neurons":"64.0","Oligodendrocytes":"168.1","Proximal tubular cells":"185.3","Syncytiotrophoblasts":"71.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"11.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Prostate - Prostate glandular cells","Stomach - Chief cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014333","HPA014353","HPA014736"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014333":"AB_2732407","HPA014353":"AB_1856968","HPA014736":"AB_1856970"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"}},{"Gene":"SLC13A4","Gene synonym":["SUT-1","SUT1"],"Ensembl":"ENSG00000164707","Gene description":"Solute carrier family 13 member 4","Uniprot":["Q9UKG4"],"Chromosome":"7","Position":"135681237-135729258","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"choroid plexus":"809.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"770.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.3"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"45.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"2.1","testis cancer":"3.1"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048582"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048582":"AB_2680450"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"}},{"Gene":"SLC13A5","Gene synonym":["INDY","NACT"],"Ensembl":"ENSG00000141485","Gene description":"Solute carrier family 13 member 5","Uniprot":["Q86YT5"],"Chromosome":"17","Position":"6684719-6713377","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"liver":"414.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Hepatocytes":"304.1","Kupffer cells":"144.9","Serous glandular cells":"271.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"liver cancer":"27.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Bile duct cancer":"2.8","liver cancer":"7.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044343"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA044343":"AB_10961771"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"}},{"Gene":"SLC14A1","Gene synonym":["HsT1341","JK","RACH1","RACH2"],"Ensembl":"ENSG00000141469","Gene description":"Solute carrier family 14 member 1 (Kidd blood group)","Uniprot":["Q13336"],"Chromosome":"18","Position":"45687025-45752520","Protein class":["Blood group antigen proteins","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Blood group antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"133.8","prostate":"78.3","urinary bladder":"90.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"94.5","Astrocytes":"221.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"5.3","prostate cancer":"8.6","urothelial cancer":"16.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"4.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"34.0","thyroid cancer":"33.8"},"RNA tissue cell type enrichment":["Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059570","HPA077233"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA059570":"AB_2684066","HPA077233":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"}},{"Gene":"SLC14A2","Gene synonym":["HUT2","UT2"],"Ensembl":"ENSG00000132874","Gene description":"Solute carrier family 14 member 2","Uniprot":["Q15849"],"Chromosome":"18","Position":"45212995-45683688","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"1.5","kidney":"3.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Collecting duct cells":"76.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"1.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Uterine cancer":"3.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"16.9"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"}},{"Gene":"SLC15A1","Gene synonym":["HPECT1","HPEPT1","PEPT1"],"Ensembl":"ENSG00000088386","Gene description":"Solute carrier family 15 member 1","Uniprot":["P46059"],"Chromosome":"13","Position":"98683801-98752672","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Peptide transport","Protein transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"203.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"358.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"10.4"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Liver - Hepatocytes","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002827"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002827":"AB_1856974"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"}},{"Gene":"SLC15A2","Gene synonym":["PEPT2"],"Ensembl":"ENSG00000163406","Gene description":"Solute carrier family 15 member 2","Uniprot":["Q16348"],"Chromosome":"3","Position":"121894401-121944188","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Immunity","Innate immunity","Peptide transport","Protein transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"50.9","epididymis":"39.2","prostate":"39.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"70.3","Astrocytes":"135.4","Club cells":"77.0","Ionocytes":"63.6","Microglial cells":"48.3","Prostatic glandular cells":"45.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"12.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.37e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.96e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.74e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"}},{"Gene":"SLC15A3","Gene synonym":["hPTR3","PHT2"],"Ensembl":"ENSG00000110446","Gene description":"Solute carrier family 15 member 3","Uniprot":["Q8IY34"],"Chromosome":"11","Position":"60937060-60952653","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Immunity","Innate immunity","Peptide transport","Protein transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"94.7","Langerhans cells":"55.3","Macrophages":"80.2","monocytes":"90.6","Muller glia cells":"201.1","Schwann cells":"110.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"9.0","intermediate monocyte":"12.8","memory B-cell":"4.9","myeloid DC":"6.5","neutrophil":"13.4","non-classical monocyte":"6.4","plasmacytoid DC":"10.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"16.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047880","HPA057642"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA047880":"AB_10959455","HPA057642":"AB_2683487"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.07e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"SLC15A4","Gene synonym":["PHT1","PTR4"],"Ensembl":"ENSG00000139370","Gene description":"Solute carrier family 15 member 4","Uniprot":["Q8N697"],"Chromosome":"12","Position":"128793194-128823958","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Immunity","Innate immunity","Peptide transport","Protein transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"426.4","Late spermatids":"114.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"31.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016713"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016713":"AB_1856978"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.45e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.78e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.56e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"}},{"Gene":"SLC15A5","Gene synonym":[],"Ensembl":"ENSG00000188991","Gene description":"Solute carrier family 15 member 5","Uniprot":["A6NIM6"],"Chromosome":"12","Position":"16188485-16277685","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Peptide transport","Protein transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1.9","Cone photoreceptor cells":"1.7","Early spermatids":"5.1","Excitatory neurons":"1.1","Late spermatids":"1.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041638"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041638":"AB_2677590"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-6"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC16A1","Gene synonym":["MCT","MCT1"],"Ensembl":"ENSG00000155380","Gene description":"Solute carrier family 16 member 1","Uniprot":["P53985"],"Chromosome":"1","Position":"112911847-112957593","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"151.1","Cone photoreceptor cells":"153.4","Granulosa cells":"341.7","Muller glia cells":"169.9","Rod photoreceptor cells":"338.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"6.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003324","CAB017489","HPA071055","CAB079035"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB017489":"AB_2189197","CAB079035":null,"HPA003324":"AB_1856982","HPA071055":"AB_2686337"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.37e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.05e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.78e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"}},{"Gene":"SLC16A10","Gene synonym":["MCT10","TAT1"],"Ensembl":"ENSG00000112394","Gene description":"Solute carrier family 16 member 10","Uniprot":["Q8TF71"],"Chromosome":"6","Position":"111087503-111231194","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"53.7","skeletal muscle":"41.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"46.7","Macrophages":"35.3","Melanocytes":"67.9","Skeletal myocytes":"90.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"testis cancer":"4.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"1.7","T-reg":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Kidney - Proximal tubular cells","Stomach - Chief cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016860"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA016860":"AB_2189211"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"}},{"Gene":"SLC16A11","Gene synonym":["FLJ90193","MCT11"],"Ensembl":"ENSG00000174326","Gene description":"Solute carrier family 16 member 11","Uniprot":["Q8NCK7"],"Chromosome":"17","Position":"7041621-7044092","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid metabolism","Symport","Transport"],"Molecular function":null,"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"13.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"13.6","Ionocytes":"12.3","Muller glia cells":"27.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"12.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"B-cells":"1.0","T-cells":"1.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"1.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.45e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.19e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"}},{"Gene":"SLC16A12","Gene synonym":["MCT12"],"Ensembl":"ENSG00000152779","Gene description":"Solute carrier family 16 member 12","Uniprot":["Q6ZSM3"],"Chromosome":"10","Position":"89430299-89556641","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Cataract"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"choroid plexus":"92.2","epididymis":"51.8","kidney":"85.2","pancreas":"25.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"72.9","Collecting duct cells":"21.7","Distal tubular cells":"24.9","Leydig cells":"28.2","Peritubular cells":"28.0","Proximal tubular cells":"79.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"renal cancer":"18.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"8.4","liver cancer":"5.7"},"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.50e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"}},{"Gene":"SLC16A13","Gene synonym":["MCT13"],"Ensembl":"ENSG00000174327","Gene description":"Solute carrier family 16 member 13","Uniprot":["Q7RTY0"],"Chromosome":"17","Position":"7036015-7040117","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"36.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"5.8","Collecting duct cells":"5.9","Hepatocytes":"6.5","Squamous epithelial cells":"6.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065245"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA065245":"AB_2685443"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"}},{"Gene":"SLC16A14","Gene synonym":["FLJ30794","MCT14"],"Ensembl":"ENSG00000163053","Gene description":"Solute carrier family 16 member 14","Uniprot":["Q7RTX9"],"Chromosome":"2","Position":"230034982-230068993","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"18.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"16.4","Excitatory neurons":"18.3","Inhibitory neurons":"20.6","Microglial cells":"43.8","Oligodendrocyte precursor cells":"13.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"24","RNA blood cell specific nTPM":{"eosinophil":"11.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"24","RNA blood lineage specific nTPM":{"granulocytes":"11.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Kidney - Endothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040518"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA040518":"AB_10794877"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"}},{"Gene":"SLC16A2","Gene synonym":["AHDS","DXS128","MCT7","MCT8","MRX22","XPCT"],"Ensembl":"ENSG00000147100","Gene description":"Solute carrier family 16 member 2","Uniprot":["P36021"],"Chromosome":"X","Position":"74421493-74533917","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"40.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"21.5","Hepatocytes":"53.2","Inhibitory neurons":"21.1","Oligodendrocyte precursor cells":"22.1","Peritubular cells":"20.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Liver - Hepatocytes","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072719"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA072719":"AB_2686552"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.88e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.16e-4"}},{"Gene":"SLC16A3","Gene synonym":["MCT3","MCT4"],"Ensembl":"ENSG00000141526","Gene description":"Solute carrier family 16 member 3","Uniprot":["O15427"],"Chromosome":"17","Position":"82217934-82261129","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"198.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"1967.1","Syncytiotrophoblasts":"699.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"109.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Neutrophil_2","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017490","HPA021451"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"CAB017490":"AB_2189333","HPA021451":"AB_1853663"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.07e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.19e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.71e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"}},{"Gene":"SLC16A4","Gene synonym":["MCT4","MCT5"],"Ensembl":"ENSG00000168679","Gene description":"Solute carrier family 16 member 4","Uniprot":["O15374"],"Chromosome":"1","Position":"110362851-110391082","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"kidney":"124.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"57.1","Extravillous trophoblasts":"39.4","Proximal tubular cells":"156.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"35.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"1.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"33.2"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Fibroblasts","Kidney - Proximal tubular cells","Liver - Hepatocytes","Prostate - Fibroblasts","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046986","HPA060163"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Microtubules","Cytosol"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA046986":"AB_2679892","HPA060163":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"}},{"Gene":"SLC16A5","Gene synonym":["MCT5","MCT6"],"Ensembl":"ENSG00000170190","Gene description":"Solute carrier family 16 member 5","Uniprot":["O15375"],"Chromosome":"17","Position":"75087727-75106162","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"92.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"45.7","Collecting duct cells":"84.7","Late spermatids":"41.5","Proximal enterocytes":"43.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"13.2","neutrophil":"34.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"34.9","monocytes":"13.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Lung - Alveolar cells type 2","Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"}},{"Gene":"SLC16A6","Gene synonym":["MCT6","MCT7"],"Ensembl":"ENSG00000108932","Gene description":"Solute carrier family 16 member 6","Uniprot":["O15403"],"Chromosome":"17","Position":"68267026-68291267","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"51.0","epididymis":"33.3","retina":"31.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"53.4","Glandular and luminal cells":"30.6","Kupffer cells":"30.1","Macrophages":"26.7","monocytes":"25.4","Rod photoreceptor cells":"44.9","Suprabasal keratinocytes":"21.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"breast cancer":"10.9","melanoma":"11.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"skin cancer":"101.7"},"RNA tissue cell type enrichment":["Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054459","HPA066328"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA054459":"AB_2682494","HPA066328":"AB_2685660"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"}},{"Gene":"SLC16A7","Gene synonym":["MCT2"],"Ensembl":"ENSG00000118596","Gene description":"Solute carrier family 16 member 7","Uniprot":["O60669"],"Chromosome":"12","Position":"59596029-59789855","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"34.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"178.1","Early spermatids":"115.1","Excitatory neurons":"148.4","Inhibitory neurons":"125.3","Late spermatids":"139.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"cerebellum":"22.2"},"Antibody":["HPA005911"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA005911":"AB_1853659"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.85e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"}},{"Gene":"SLC16A8","Gene synonym":["MCT3","REMP"],"Ensembl":"ENSG00000100156","Gene description":"Solute carrier family 16 member 8","Uniprot":["O95907"],"Chromosome":"22","Position":"38078134-38084093","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"9.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"3.4","Muller glia cells":"4.2","Oligodendrocytes":"3.8","Skeletal myocytes":"4.9","Spermatogonia":"8.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"4.5"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075017"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 47: Spermatogonia - Spermatogenesis","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"HPA075017":"AB_2732276"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-5"}},{"Gene":"SLC16A9","Gene synonym":["C10orf36","FLJ43803","MCT9"],"Ensembl":"ENSG00000165449","Gene description":"Solute carrier family 16 member 9","Uniprot":["Q7RTY1"],"Chromosome":"10","Position":"59650764-59736002","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adrenal gland":"151.3","kidney":"191.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"81.3","Distal enterocytes":"48.7","Proximal tubular cells":"177.8","Theca cells":"70.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"21.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Testis - Leydig cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049286"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA049286":"AB_2680699"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"}},{"Gene":"SLC17A1","Gene synonym":["NAPI-1","NPT1"],"Ensembl":"ENSG00000124568","Gene description":"Solute carrier family 17 member 1","Uniprot":["Q14916"],"Chromosome":"6","Position":"25782915-25832052","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"49","RNA tissue specific nTPM":{"kidney":"169.3","liver":"49.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"11.2","Hepatocytes":"8.8","Proximal tubular cells":"42.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"150","RNA cancer specific FPKM":{"liver cancer":"7.6","renal cancer":"19.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Kidney cancer":"13.4"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050513"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA050513":"AB_2681152"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC17A2","Gene synonym":["NPT3"],"Ensembl":"ENSG00000112337","Gene description":"Solute carrier family 17 member 2","Uniprot":["O00624"],"Chromosome":"6","Position":"25912754-25930691","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"165","RNA tissue specific nTPM":{"liver":"79.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Hepatocytes":"27.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"liver cancer":"14.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038270"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038270":"AB_10672511"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.54e-4"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC17A3","Gene synonym":["NPT4"],"Ensembl":"ENSG00000124564","Gene description":"Solute carrier family 17 member 3","Uniprot":["O00476"],"Chromosome":"6","Position":"25833066-25882286","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"kidney":"164.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Proximal tubular cells":"150.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"renal cancer":"57.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"21","RNA cell line specific nTPM":{"Kidney cancer":"48.7"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC17A4","Gene synonym":["KIAA2138"],"Ensembl":"ENSG00000146039","Gene description":"Solute carrier family 17 member 4","Uniprot":["Q9Y2C5"],"Chromosome":"6","Position":"25754699-25781199","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"gallbladder":"16.3","intestine":"31.9","liver":"47.3","pancreas":"22.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"82.8","Distal enterocytes":"68.9","Hepatocytes":"34.3","Intestinal goblet cells":"20.1","Paneth cells":"37.0","Proximal enterocytes":"43.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"liver cancer":"11.0","renal cancer":"7.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"3.3"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"cerebellum":"1.5"},"Antibody":["HPA055564"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055564":"AB_2682852"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC17A5","Gene synonym":["AST","ISSD","NSD","SD","SIALIN","SIASD","SLD"],"Ensembl":"ENSG00000119899","Gene description":"Solute carrier family 17 member 5","Uniprot":["Q9NRA2"],"Chromosome":"6","Position":"73593379-73653992","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"parathyroid gland":"310.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"47.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044479"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA044479":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.52e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"SLC17A6","Gene synonym":["DNPI","VGLUT2"],"Ensembl":"ENSG00000091664","Gene description":"Solute carrier family 17 member 6","Uniprot":["Q9P2U8"],"Chromosome":"11","Position":"22338381-22379503","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Neurotransmitter transport","Phosphate transport","Sodium transport","Symport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"39.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"14.3","Horizontal cells":"17.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"1.5","skin cancer":"1.3"},"RNA tissue cell type enrichment":["Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"51.9","hypothalamus":"139.9","midbrain":"172.4","pons and medulla":"86.4","thalamus":"164.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037130","HPA039226","CAB078204"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037130":"AB_477611","CAB078204":"AB_2665794","HPA039226":"AB_2676400"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC17A7","Gene synonym":["BNPI","VGLUT1"],"Ensembl":"ENSG00000104888","Gene description":"Solute carrier family 17 member 7","Uniprot":["Q9P2U7"],"Chromosome":"19","Position":"49429401-49442360","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Neurotransmitter transport","Phosphate transport","Sodium transport","Symport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"63","RNA tissue specific nTPM":{"brain":"405.4","retina":"315.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"358.5","Cone photoreceptor cells":"489.4","Excitatory neurons":"106.3","Rod photoreceptor cells":"397.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"7.5"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"amygdala":"176.7","basal ganglia":"243.4","cerebral cortex":"289.7","hippocampal formation":"405.4","white matter":"169.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"15.4"},"RNA tissue cell type enrichment":["Lung - Fibroblast_2","Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"amygdala":"201.2","cerebellum":"204.6","cerebral cortex":"339.5","hippocampal formation":"471.2"},"Antibody":["CAB037183","HPA050458","HPA063679"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037183":"AB_261840","HPA050458":"AB_2681134","HPA063679":"AB_2685086"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-3"}},{"Gene":"SLC17A8","Gene synonym":["DFNA25","VGLUT3"],"Ensembl":"ENSG00000179520","Gene description":"Solute carrier family 17 member 8","Uniprot":["Q8NDX2"],"Chromosome":"12","Position":"100357074-100422055","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Hearing","Ion transport","Neurotransmitter transport","Phosphate transport","Sodium transport","Symport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"11.3","intestine":"5.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"11.4","Extravillous trophoblasts":"4.4","Inhibitory neurons":"6.4","Proximal enterocytes":"34.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.5"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"11.3","midbrain":"8.3","pons":"6.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038870","CAB079058"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB079058":null,"HPA038870":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC17A9","Gene synonym":["C20orf59","FLJ23412","VNUT"],"Ensembl":"ENSG00000101194","Gene description":"Solute carrier family 17 member 9","Uniprot":["Q9BYT1"],"Chromosome":"20","Position":"62952707-62969585","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Exocytosis","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"43.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"23.8","Hepatocytes":"32.7","Hofbauer cells":"16.4","Plasma cells":"48.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"4.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"30.1"},"RNA tissue cell type enrichment":["Breast - Plasma cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047470"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA047470":"AB_2680060"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"SLC18A1","Gene synonym":["CGAT","VAT1","VMAT1"],"Ensembl":"ENSG00000036565","Gene description":"Solute carrier family 18 member A1","Uniprot":["P54219"],"Chromosome":"8","Position":"20144855-20183206","Protein class":["FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"adrenal gland":"25.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"55","RNA single cell type specific nTPM":{"Enteroendocrine cells":"101.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"0.8"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"19","RNA brain regional specific nTPM":{"midbrain":"3.9"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"2.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"monocytes":"2.8"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Neuroblastoma":"31.9"},"RNA tissue cell type enrichment":["Skin - Outer root sheath cells","Stomach - Gastric enteroendocrine cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006877","HPA063797"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA006877":"AB_2667690","HPA063797":"AB_2685125"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"SLC18A2","Gene synonym":["SVAT","SVMT","VMAT2"],"Ensembl":"ENSG00000165646","Gene description":"Solute carrier family 18 member A2","Uniprot":["Q05940"],"Chromosome":"10","Position":"117241093-117279430","Protein class":["Disease related genes","FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Dystonia","FDA approved drug targets","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"81.1","cervix":"30.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Glandular and luminal cells":"122.4","granulocytes":"430.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"11","RNA brain regional specific nTPM":{"hypothalamus":"20.8","midbrain":"81.1","pons":"70.5"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"basophil":"59.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"granulocytes":"59.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"10.4","Neuroblastoma":"6.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Adipose visceral - Mast cells","Colon - Mast cells","Lung - Mast cells","Skin - Langerhans cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"midbrain":"62.7"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"midbrain":"111.6"},"Antibody":["HPA073224"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":["Vesicles","Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA073224":"AB_2732222"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"}},{"Gene":"SLC18A3","Gene synonym":["VACHT"],"Ensembl":"ENSG00000187714","Gene description":"Solute carrier family 18 member A3","Uniprot":["Q16572"],"Chromosome":"10","Position":"49610310-49612720","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"21","RNA tissue specific nTPM":{"brain":"25.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Smooth muscle cells":"3.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"liver cancer":"4.1","Neuroblastoma":"12.8"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"spinal cord":"78.1"},"Antibody":["CAB079011"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079011":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC18B1","Gene synonym":["C6orf192","dJ55C23.6"],"Ensembl":"ENSG00000146409","Gene description":"Solute carrier family 18 member B1","Uniprot":["Q6NT16"],"Chromosome":"6","Position":"132769370-132813339","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"90.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029747"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA029747":"AB_10600797"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.55e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.90e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"}},{"Gene":"SLC19A1","Gene synonym":["FOLT","RFC1"],"Ensembl":"ENSG00000173638","Gene description":"Solute carrier family 19 member 1","Uniprot":["P41440"],"Chromosome":"21","Position":"45493572-45573365","Protein class":["Cancer-related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"82.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Cytotrophoblasts":"153.1","Syncytiotrophoblasts":"348.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"102.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"102.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024802"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA024802":"AB_10602892"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.15e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.07e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"}},{"Gene":"SLC19A2","Gene synonym":["THTR1","TRMA"],"Ensembl":"ENSG00000117479","Gene description":"Solute carrier family 19 member 2","Uniprot":["O60779"],"Chromosome":"1","Position":"169463909-169485944","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Deafness","Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"124.1","tongue":"84.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"107.9","Syncytiotrophoblasts":"201.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006119","HPA016599"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA006119":"AB_1079996","HPA016599":"AB_1857005"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.41e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.70e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"}},{"Gene":"SLC19A3","Gene synonym":["THTR2"],"Ensembl":"ENSG00000135917","Gene description":"Solute carrier family 19 member 3","Uniprot":["Q9BZV2"],"Chromosome":"2","Position":"227683763-227718028","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"46.7","breast":"28.4","placenta":"24.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"67.0","Syncytiotrophoblasts":"168.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"6.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"9.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skin - Adipocytes (Skin)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038898"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA038898":"AB_10673481"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-3"}},{"Gene":"SLC1A1","Gene synonym":["EAAC1","EAAT3"],"Ensembl":"ENSG00000106688","Gene description":"Solute carrier family 1 member 1","Uniprot":["P43005"],"Chromosome":"9","Position":"4490468-4587469","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Schizophrenia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"45.0","intestine":"64.7","kidney":"51.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"66.0","Glandular and luminal cells":"122.1","Hepatocytes":"58.4","Inhibitory neurons":"48.9","Microglial cells":"65.7","Oligodendrocyte precursor cells":"154.5","Proximal enterocytes":"95.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes","Lung - Alveolar cells type 1","Skeletal muscle - Endothelial cells","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062356"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062356":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.86e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"}},{"Gene":"SLC1A2","Gene synonym":["EAAT2","GLT-1"],"Ensembl":"ENSG00000110436","Gene description":"Solute carrier family 1 member 2","Uniprot":["P43004"],"Chromosome":"11","Position":"35251205-35420063","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"782.3","choroid plexus":"202.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"4463.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"28.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"6.2","Neuroblastoma":"3.8"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Stomach - Chief cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002574","HPA009172","HPA067499"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002574":"AB_564087","HPA009172":"AB_1849764","HPA067499":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"}},{"Gene":"SLC1A3","Gene synonym":["EA6","EAAT1","GLAST"],"Ensembl":"ENSG00000079215","Gene description":"Solute carrier family 1 member 3","Uniprot":["P43003"],"Chromosome":"5","Position":"36596588-36688334","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"776.8","choroid plexus":"400.6","retina":"221.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1681.2","Microglial cells":"323.8","Muller glia cells":"519.5","Oligodendrocyte precursor cells":"227.7","Oligodendrocytes":"235.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"21","RNA cancer specific FPKM":{"glioma":"168.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"classical monocyte":"1.5","intermediate monocyte":"1.2","myeloid DC":"1.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"dendritic cells":"1.6","monocytes":"1.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Kidney - Macrophages","Lung - Macrophages","Pancreas - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002573","HPA037467","HPA037468"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoli","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB002573":"AB_564088","HPA037467":"AB_10795027","HPA037468":"AB_10671371"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"}},{"Gene":"SLC1A4","Gene synonym":["ASCT1","SATT"],"Ensembl":"ENSG00000115902","Gene description":"Solute carrier family 1 member 4","Uniprot":["P43007"],"Chromosome":"2","Position":"64988477-65023865","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"59.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"67.7","dendritic cells":"87.0","Melanocytes":"153.3","Plasma cells":"64.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"91.0","skin cancer":"96.7"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034963","HPA034964"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA034963":"AB_2797223","HPA034964":"AB_2674386"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.23e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"}},{"Gene":"SLC1A5","Gene synonym":["AAAT","ASCT2","M7V1","RDRC"],"Ensembl":"ENSG00000105281","Gene description":"Solute carrier family 1 member 5","Uniprot":["Q15758"],"Chromosome":"19","Position":"46774883-46788594","Protein class":["FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Host-virus interaction","Symport","Transport"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"95.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035239","HPA035240"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA035239":"AB_10670587","HPA035240":"AB_10604092"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.66e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.18e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"}},{"Gene":"SLC1A6","Gene synonym":["EAAT4"],"Ensembl":"ENSG00000105143","Gene description":"Solute carrier family 1 member 6","Uniprot":["P48664"],"Chromosome":"19","Position":"14950034-15022990","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"88.2","testis":"28.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"13.3","Early spermatids":"31.9","Extravillous trophoblasts":"12.4","Horizontal cells":"10.9","Late spermatids":"36.7","Syncytiotrophoblasts":"44.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"urothelial cancer":"5.2"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"88.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"9.7","breast cancer":"9.8"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"cerebellum":"136.3"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"53.8"},"Antibody":["HPA041505","HPA044066"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"HPA041505":"AB_2677520","HPA044066":"AB_2678796"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.88e-6"}},{"Gene":"SLC1A7","Gene synonym":["EAAT5"],"Ensembl":"ENSG00000162383","Gene description":"Solute carrier family 1 member 7","Uniprot":["O00341"],"Chromosome":"1","Position":"53087179-53142638","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"retina":"40.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Bipolar cells":"186.9","Cone photoreceptor cells":"81.0","Rod photoreceptor cells":"70.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"3.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"2.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"T-cells":"2.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Brain cancer":"4.9","breast cancer":"9.9"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Heart muscle - Fibroblasts","Lung - Fibroblast_2","Pancreas - Fibroblasts","Prostate - Fibroblasts","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049124"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049124":"AB_2680643"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-3"}},{"Gene":"SLC20A1","Gene synonym":["Glvr-1","GLVR1","PiT-1"],"Ensembl":"ENSG00000144136","Gene description":"Solute carrier family 20 member 1","Uniprot":["Q8WUM9"],"Chromosome":"2","Position":"112645939-112663825","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction","Phosphate transport","Symport","Transport"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"251.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019279","HPA035834","HPA064386"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB019279":null,"HPA035834":"AB_2674809","HPA064386":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.56e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.44e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-3"}},{"Gene":"SLC20A2","Gene synonym":["Glvr-2","GLVR2","MLVAR","PiT-2","Ram-1"],"Ensembl":"ENSG00000168575","Gene description":"Solute carrier family 20 member 2","Uniprot":["Q08357"],"Chromosome":"8","Position":"42416475-42541926","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction","Ion transport","Phosphate transport","Sodium transport","Symport","Transport"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"130.6","skeletal muscle":"131.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"143.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Smooth muscle cells","Liver - Hepatocytes","Skeletal muscle - Skeletal myocytes","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026540"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026540":"AB_1855408"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.67e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"}},{"Gene":"SLC22A1","Gene synonym":["OCT1"],"Ensembl":"ENSG00000175003","Gene description":"Solute carrier family 22 member 1","Uniprot":["O15245"],"Chromosome":"6","Position":"160121815-160158718","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"381","RNA tissue specific nTPM":{"liver":"609.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Hepatocytes":"813.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"81","RNA cancer specific FPKM":{"liver cancer":"83.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"neutrophil":"3.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"granulocytes":"3.5"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029846"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029846":"AB_10603026"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-4"}},{"Gene":"SLC22A10","Gene synonym":["hOAT5","OAT5"],"Ensembl":"ENSG00000184999","Gene description":"Solute carrier family 22 member 10","Uniprot":["Q63ZE4"],"Chromosome":"11","Position":"63137867-63369718","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"160","RNA tissue specific nTPM":{"liver":"100.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"6.3","Hepatocytes":"22.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"liver cancer":"6.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC22A11","Gene synonym":["OAT4"],"Ensembl":"ENSG00000168065","Gene description":"Solute carrier family 22 member 11","Uniprot":["Q9NSA0"],"Chromosome":"11","Position":"64555690-64572875","Protein class":["FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"72","RNA tissue specific nTPM":{"epididymis":"10.6","kidney":"31.9","placenta":"33.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"33","RNA single cell type specific nTPM":{"Cytotrophoblasts":"634.5","Syncytiotrophoblasts":"1740.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"renal cancer":"15.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026076"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026076":"AB_1854756"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.68e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-3"}},{"Gene":"SLC22A12","Gene synonym":["OAT4L","RST","URAT1"],"Ensembl":"ENSG00000197891","Gene description":"Solute carrier family 22 member 12","Uniprot":["Q96S37"],"Chromosome":"11","Position":"64590641-64602353","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"204","RNA tissue specific nTPM":{"kidney":"109.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Proximal tubular cells":"129.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"renal cancer":"16.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024575"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024575":"AB_1858650"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC22A13","Gene synonym":["OAT10","OCTL1","OCTL3","ORCTL3"],"Ensembl":"ENSG00000172940","Gene description":"Solute carrier family 22 member 13","Uniprot":["Q9Y226"],"Chromosome":"3","Position":"38265812-38278757","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"kidney":"9.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"4.5","Ionocytes":"3.0","Proximal tubular cells":"6.7","Sertoli cells":"2.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"renal cancer":"0.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035603","HPA035962"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035603":"AB_10672869","HPA035962":"AB_2674890"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"}},{"Gene":"SLC22A14","Gene synonym":["OCTL2","ORCTL4"],"Ensembl":"ENSG00000144671","Gene description":"Solute carrier family 22 member 14","Uniprot":["Q9Y267"],"Chromosome":"3","Position":"38282294-38318575","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"11.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"67.8","Late spermatids":"103.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"}},{"Gene":"SLC22A15","Gene synonym":["FLIPT1"],"Ensembl":"ENSG00000163393","Gene description":"Solute carrier family 22 member 15","Uniprot":["Q8IZD6"],"Chromosome":"1","Position":"115976513-116070054","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"30.6","brain":"31.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"236.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.3","non-classical monocyte":"1.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"1.3","monocytes":"1.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019785"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019785":"AB_1857011"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"}},{"Gene":"SLC22A16","Gene synonym":["CT2","FLIPT2","OAT6","OKB1"],"Ensembl":"ENSG00000004809","Gene description":"Solute carrier family 22 member 16","Uniprot":["Q86VW1"],"Chromosome":"6","Position":"110424687-110476641","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Ion transport","Spermatogenesis","Transport"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"20.5","testis":"21.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Early spermatids":"39.5","Erythroid cells":"50.3","Late spermatids":"31.1","Spermatocytes":"34.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"endometrial cancer":"0.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"5.7","classical monocyte":"6.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"56","RNA blood lineage specific nTPM":{"dendritic cells":"4.0","granulocytes":"5.7","monocytes":"6.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Leukemia":"10.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Liver - Erythroid cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036902"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA036902":"AB_10672274"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"}},{"Gene":"SLC22A17","Gene synonym":["BOCT","BOIT","NGALR"],"Ensembl":"ENSG00000092096","Gene description":"Solute carrier family 22 member 17","Uniprot":["Q8WUG5"],"Chromosome":"14","Position":"23346306-23352912","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Iron transport","Transport"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"304.0","choroid plexus":"372.6","pituitary gland":"149.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"139.7","Inhibitory neurons":"108.3","Oligodendrocyte precursor cells":"115.5","Prostatic glandular cells":"144.3","Rod photoreceptor cells":"75.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"51.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"29.1"},"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Colon - Enteric glia cells","Pancreas - Alpha cells","Prostate - Prostate glandular cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002728"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002728":"AB_1079998"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.95e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"}},{"Gene":"SLC22A18","Gene synonym":["BWR1A","BWSCR1A","IMPT1","ITM","ORCTL2","SLC22A1L","TSSC5"],"Ensembl":"ENSG00000110628","Gene description":"Solute carrier family 22 member 18","Uniprot":["Q96BI1"],"Chromosome":"11","Position":"2899721-2925246","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"42.3","liver":"45.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"324.4","Late spermatids":"511.1","Paneth cells":"262.1","Proximal enterocytes":"774.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067812","HPA071461"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA067812":"AB_2685902","HPA071461":"AB_2686401"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"}},{"Gene":"SLC22A2","Gene synonym":["OCT2"],"Ensembl":"ENSG00000112499","Gene description":"Solute carrier family 22 member 2","Uniprot":["O15244"],"Chromosome":"6","Position":"160171061-160277638","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"105","RNA tissue specific nTPM":{"kidney":"153.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Distal tubular cells":"56.0","Proximal tubular cells":"144.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"493","RNA cancer specific FPKM":{"renal cancer":"30.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Kidney cancer":"3.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"midbrain":"1.9"},"Antibody":["HPA008549","CAB068236","CAB068237"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB068236":"AB_2665668","CAB068237":"AB_2665669","HPA008549":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"}},{"Gene":"SLC22A23","Gene synonym":["C6orf85","FLJ22174"],"Ensembl":"ENSG00000137266","Gene description":"Solute carrier family 22 member 23","Uniprot":["A1A5C7"],"Chromosome":"6","Position":"3268962-3457050","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"50.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"237.3","Oligodendrocytes":"269.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014697"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA014697":"AB_1844371"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.57e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"}},{"Gene":"SLC22A24","Gene synonym":["MGC34821","NET46"],"Ensembl":"ENSG00000197658","Gene description":"Solute carrier family 22 member 24","Uniprot":["Q8N4F4"],"Chromosome":"11","Position":"63079940-63144221","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Lipid metabolism","Steroid metabolism","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"1.1","kidney":"4.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"5.8","Proximal tubular cells":"10.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"renal cancer":"0.5"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"1.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045015"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045015":"AB_2679183"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-7"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC22A25","Gene synonym":["HIMTP","MGC120420","UST6"],"Ensembl":"ENSG00000196600","Gene description":"Solute carrier family 22 member 25","Uniprot":["Q6T423"],"Chromosome":"11","Position":"63163776-63229652","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"liver":"11.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"3.4","Hepatocytes":"4.9","Inhibitory neurons":"1.1","Oligodendrocyte precursor cells":"1.4","Oligodendrocytes":"1.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"66","RNA cancer specific FPKM":{"liver cancer":"3.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039390"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039390":"AB_10671996"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.04e-4"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC22A3","Gene synonym":["EMT","OCT3"],"Ensembl":"ENSG00000146477","Gene description":"Solute carrier family 22 member 3","Uniprot":["O75751"],"Chromosome":"6","Position":"160348378-160452577","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"67.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"42.2","Hepatocytes":"54.2","Leydig cells":"37.2","Peritubular cells":"26.0","Prostatic glandular cells":"81.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"19.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"27.0"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Smooth muscle cells","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029750"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA029750":"AB_10603888"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.19e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.26e-4"}},{"Gene":"SLC22A31","Gene synonym":[],"Ensembl":"ENSG00000259803","Gene description":"Solute carrier family 22 member 31","Uniprot":["A6NKX4"],"Chromosome":"16","Position":"89195761-89201651","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"24.5","lung":"40.6","pancreas":"33.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 1":"75.2","Alveolar cells type 2":"277.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"26.2","thyroid cancer":"20.4"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"10","RNA brain regional specific nTPM":{"cerebellum":"24.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"9.9"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"}},{"Gene":"SLC22A4","Gene synonym":["DFNB60","MGC34546","OCTN1"],"Ensembl":"ENSG00000197208","Gene description":"Solute carrier family 22 member 4","Uniprot":["Q9H015"],"Chromosome":"5","Position":"132294394-132344190","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"20.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Erythroid cells":"34.9","Proximal enterocytes":"25.4","Respiratory ciliated cells":"68.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"36.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"36.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"64.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015468","HPA036974"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB015468":null,"HPA036974":"AB_2732474"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"}},{"Gene":"SLC22A5","Gene synonym":["CDSP","OCTN2","SCD"],"Ensembl":"ENSG00000197375","Gene description":"Solute carrier family 22 member 5","Uniprot":["O76082"],"Chromosome":"5","Position":"132369710-132395613","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"56.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"44.8","Proximal enterocytes":"45.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"8.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063062"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA063062":"AB_2684934"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.87e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"}},{"Gene":"SLC22A6","Gene synonym":["OAT1","PAHT","ROAT1"],"Ensembl":"ENSG00000197901","Gene description":"Solute carrier family 22 member 6","Uniprot":["Q4U2R8"],"Chromosome":"11","Position":"62936385-62984967","Protein class":["FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"26","RNA tissue specific nTPM":{"kidney":"196.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"36","RNA single cell type specific nTPM":{"Proximal tubular cells":"172.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"102","RNA cancer specific FPKM":{"renal cancer":"18.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074559","CAB075704"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB075704":null,"HPA074559":"AB_2732260"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC22A7","Gene synonym":["NLT","OAT2"],"Ensembl":"ENSG00000137204","Gene description":"Solute carrier family 22 member 7","Uniprot":["Q9Y694"],"Chromosome":"6","Position":"43295694-43305538","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"liver":"427.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Hepatocytes":"188.5","Proximal tubular cells":"53.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"37","RNA cancer specific FPKM":{"liver cancer":"81.5"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"liver cancer":"1.0"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030220"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030220":"AB_10603027"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.48e-6"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.98e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC22A8","Gene synonym":["OAT3"],"Ensembl":"ENSG00000149452","Gene description":"Solute carrier family 22 member 8","Uniprot":["Q8TCC7"],"Chromosome":"11","Position":"62989154-63015841","Protein class":["FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Detoxification","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"61","RNA tissue specific nTPM":{"choroid plexus":"111.4","kidney":"335.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Proximal tubular cells":"171.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"0.6"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"3.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044174"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044174":"AB_10963058"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-4"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC22A9","Gene synonym":["FLJ23666","OAT4","OAT7","UST3"],"Ensembl":"ENSG00000149742","Gene description":"Solute carrier family 22 member 9","Uniprot":["Q8IVM8"],"Chromosome":"11","Position":"63369785-63410294","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"25","RNA tissue specific nTPM":{"liver":"46.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Excitatory neurons":"4.9","Hepatocytes":"13.8","Kupffer cells":"4.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"166","RNA cancer specific FPKM":{"liver cancer":"19.3"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"1.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"liver cancer":"4.2","Myeloma":"1.8"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"}},{"Gene":"SLC23A1","Gene synonym":["SLC23A2","SVCT1","YSPL3"],"Ensembl":"ENSG00000170482","Gene description":"Solute carrier family 23 member 1","Uniprot":["Q9UHI7"],"Chromosome":"5","Position":"139367196-139384553","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"fallopian tube":"54.2","intestine":"65.3","kidney":"40.2","liver":"22.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"62.6","Proximal enterocytes":"130.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"endometrial cancer":"2.1","liver cancer":"7.7","prostate cancer":"4.0","renal cancer":"3.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"3.2"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"12.6","Myeloma":"19.5"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Lung - Respiratory ciliated cells","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047612"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047612":"AB_2680102"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-3"}},{"Gene":"SLC23A2","Gene synonym":["KIAA0238","SLC23A1","SVCT2","YSPL2"],"Ensembl":"ENSG00000089057","Gene description":"Solute carrier family 23 member 2","Uniprot":["Q9UGH3"],"Chromosome":"20","Position":"4852356-5010293","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"99.3","choroid plexus":"88.4","retina":"107.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"203.9","Excitatory neurons":"101.2","Inhibitory neurons":"114.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052825","HPA059314"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA052825":"AB_2681965","HPA059314":"AB_2683975"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.35e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.14e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.08e-5"}},{"Gene":"SLC23A3","Gene synonym":["FLJ31168","SVCT3","Yspl1"],"Ensembl":"ENSG00000213901","Gene description":"Solute carrier family 23 member 3","Uniprot":["Q6PIS1"],"Chromosome":"2","Position":"219161465-219170095","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"intestine":"18.4","kidney":"45.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Proximal enterocytes":"51.1","Proximal tubular cells":"12.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"renal cancer":"5.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"1.3"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019059"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA019059":"AB_1857017"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-5"}},{"Gene":"SLC24A1","Gene synonym":["CSNB1D","HsT17412","KIAA0702","NCKX","NCKX1","RODX"],"Ensembl":"ENSG00000074621","Gene description":"Solute carrier family 24 member 1","Uniprot":["O60721"],"Chromosome":"15","Position":"65611366-65660995","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Sensory transduction","Symport","Transport","Vision"],"Molecular function":null,"Disease involvement":["Congenital stationary night blindness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"34","RNA tissue specific nTPM":{"retina":"193.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"301.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039370"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA039370":"AB_10960279"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"}},{"Gene":"SLC24A2","Gene synonym":["NCKX2"],"Ensembl":"ENSG00000155886","Gene description":"Solute carrier family 24 member 2","Uniprot":["Q9UI40"],"Chromosome":"9","Position":"19507452-19786928","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Potassium transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"117.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"270.6","Excitatory neurons":"658.3","Inhibitory neurons":"623.9","Oligodendrocytes":"2558.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"breast cancer":"0.5","glioma":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"1.6"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079359"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA079359":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"}},{"Gene":"SLC24A3","Gene synonym":[],"Ensembl":"ENSG00000185052","Gene description":"Solute carrier family 24 member 3","Uniprot":["Q9HC58"],"Chromosome":"20","Position":"19212642-19722926","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Potassium transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"81.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Astrocytes":"130.3","Inhibitory neurons":"317.1","Oligodendrocyte precursor cells":"359.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"39","RNA blood cell specific nTPM":{"basophil":"5.8","eosinophil":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"58","RNA blood lineage specific nTPM":{"granulocytes":"5.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bile duct cancer":"6.0","Bone cancer":"15.3","breast cancer":"13.1"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Pancreas - Fibroblasts","Prostate - Smooth muscle cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043400","HPA045497"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA043400":"AB_2678462","HPA045497":"AB_2679349"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.08e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-3"}},{"Gene":"SLC24A4","Gene synonym":["NCKX4"],"Ensembl":"ENSG00000140090","Gene description":"Solute carrier family 24 member 4","Uniprot":["Q8NFF2"],"Chromosome":"14","Position":"92322581-92501481","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Olfaction","Potassium transport","Sensory transduction","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Amelogenesis imperfecta","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"choroid plexus":"92.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"45.5","Bipolar cells":"235.1","Cone photoreceptor cells":"115.5","Kupffer cells":"43.3","monocytes":"74.9","Schwann cells":"42.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"0.5","melanoma":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"11.1","intermediate monocyte":"14.7","non-classical monocyte":"11.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"14.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Sarcoma":"4.6","skin cancer":"1.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063206"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA063206":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"}},{"Gene":"SLC24A5","Gene synonym":["JSX","OCA6"],"Ensembl":"ENSG00000188467","Gene description":"Solute carrier family 24 member 5","Uniprot":["Q71RS6"],"Chromosome":"15","Position":"48120990-48142672","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Potassium transport","Sensory transduction","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Albinism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"8.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Melanocytes":"111.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"162","RNA cancer specific FPKM":{"melanoma":"8.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"43","RNA cell line specific nTPM":{"skin cancer":"79.9"},"RNA tissue cell type enrichment":["Skin - Melanocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"hippocampal formation":"3.0","pons and medulla":"4.1","thalamus":"1.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC25A10","Gene synonym":["DIC"],"Ensembl":"ENSG00000183048","Gene description":"Solute carrier family 25 member 10","Uniprot":["Q9UBX3"],"Chromosome":"17","Position":"81712236-81721016","Protein class":["Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"183.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"53.4","Late spermatids":"77.5","Proximal enterocytes":"54.1","Proximal tubular cells":"68.1","Undifferentiated cells":"65.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023048"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA023048":"AB_2301950"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.14e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.31e-4"}},{"Gene":"SLC25A14","Gene synonym":["BMCP1","UCP5"],"Ensembl":"ENSG00000102078","Gene description":"Solute carrier family 25 member 14","Uniprot":["O95258"],"Chromosome":"X","Position":"130339888-130373361","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"32.1","Spermatogonia":"38.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060316"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA060316":"AB_2684251"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.72e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.78e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.52e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.39e-5"}},{"Gene":"SLC25A39","Gene synonym":["CGI-69","FLJ22407"],"Ensembl":"ENSG00000013306","Gene description":"Solute carrier family 25 member 39","Uniprot":["Q9BZJ4"],"Chromosome":"17","Position":"44319625-44324870","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Heme biosynthesis","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"463.3","Erythroid cells":"624.6","Late spermatids":"763.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026785"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026785":"AB_10601715"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.90e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"}},{"Gene":"SLC25A47","Gene synonym":["C14orf68"],"Ensembl":"ENSG00000140107","Gene description":"Solute carrier family 25 member 47","Uniprot":["Q6Q0C1"],"Chromosome":"14","Position":"100323339-100330421","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"355","RNA tissue specific nTPM":{"liver":"534.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"53","RNA single cell type specific nTPM":{"Hepatocytes":"231.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"273","RNA cancer specific FPKM":{"liver cancer":"56.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"}},{"Gene":"SLC26A1","Gene synonym":["EDM4","SAT-1"],"Ensembl":"ENSG00000145217","Gene description":"Solute carrier family 26 member 1","Uniprot":["Q9H2B4"],"Chromosome":"4","Position":"979073-993440","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Antiport","Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"16.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"6.0","Excitatory neurons":"4.4","Hepatocytes":"9.5","Inhibitory neurons":"4.3","Oligodendrocyte precursor cells":"5.3","Proximal enterocytes":"6.7","Proximal tubular cells":"6.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"5.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"5.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"5.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041654"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA041654":"AB_10796350"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"}},{"Gene":"SLC26A11","Gene synonym":[],"Ensembl":"ENSG00000181045","Gene description":"Solute carrier family 26 member 11","Uniprot":["Q86WA9"],"Chromosome":"17","Position":"80219699-80253500","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"42.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029893"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA029893":"AB_10600809"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.82e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.43e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"}},{"Gene":"SLC26A2","Gene synonym":["DTD","DTDST"],"Ensembl":"ENSG00000155850","Gene description":"Solute carrier family 26 member 2","Uniprot":["P50443"],"Chromosome":"5","Position":"149960758-149993455","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"212.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal enterocytes":"2139.7","Glandular and luminal cells":"687.0","Syncytiotrophoblasts":"785.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"4.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041957","HPA058090"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041957":"AB_10795646","HPA058090":"AB_2683602"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.29e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.66e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.27e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"SLC26A3","Gene synonym":["CLD","DRA"],"Ensembl":"ENSG00000091138","Gene description":"Solute carrier family 26 member 3","Uniprot":["P40879"],"Chromosome":"7","Position":"107765467-107803225","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"intestine":"1120.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Distal enterocytes":"2396.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"colorectal cancer":"52.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"31","RNA cell line specific nTPM":{"colorectal cancer":"21.7"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Colon enterocytes","Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036055"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036055":"AB_10602401"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-3"}},{"Gene":"SLC26A4","Gene synonym":["DFNB4","PDS"],"Ensembl":"ENSG00000091137","Gene description":"Solute carrier family 26 member 4","Uniprot":["O43511"],"Chromosome":"7","Position":"107660828-107717809","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"thyroid gland":"263.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"28.8","Inhibitory neurons":"53.0","Ionocytes":"48.6","Serous glandular cells":"24.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"thyroid cancer":"37.6"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"88","RNA brain regional specific nTPM":{"amygdala":"4.0","basal ganglia":"10.2","cerebral cortex":"11.8","hippocampal formation":"8.8"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"naive B-cell":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"B-cells":"1.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"lymphoma":"17.0"},"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"hippocampal formation":"9.7"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"4.8"},"Antibody":["HPA042860"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042860":"AB_10796680"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"}},{"Gene":"SLC26A5","Gene synonym":["DFNB61","PRES"],"Ensembl":"ENSG00000170615","Gene description":"Solute carrier family 26 member 5","Uniprot":["P58743"],"Chromosome":"7","Position":"103352730-103446207","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cell shape","Hearing"],"Molecular function":["Motor protein"],"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"5.4","Excitatory neurons":"4.1","Fibroblasts":"2.3","Gastric mucus-secreting cells":"7.2","Inhibitory neurons":"3.5","Microglial cells":"6.4","Oligodendrocyte precursor cells":"1.9","Oligodendrocytes":"3.9","Prostatic glandular cells":"4.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"2.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Prostate - Prostate glandular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"basal ganglia":"10.4"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"}},{"Gene":"SLC26A6","Gene synonym":["DKFZp586E1422"],"Ensembl":"ENSG00000225697","Gene description":"Solute carrier family 26 member 6","Uniprot":["Q9BXS9"],"Chromosome":"3","Position":"48625723-48635493","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Antiport","Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"48.4","Intestinal goblet cells":"34.2","Paneth cells":"37.8","Proximal enterocytes":"37.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048363","HPA072381"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA048363":"AB_2680371","HPA072381":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.92e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.53e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"}},{"Gene":"SLC26A7","Gene synonym":["SUT2"],"Ensembl":"ENSG00000147606","Gene description":"Solute carrier family 26 member 7","Uniprot":["Q8TE54"],"Chromosome":"8","Position":"91209494-91398155","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"thyroid gland":"330.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"9.8","Distal tubular cells":"15.5","Early spermatids":"11.4","Endometrial ciliated cells":"27.8","Endometrial stromal cells":"19.3","Enteroendocrine cells":"21.4","Glandular and luminal cells":"46.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"renal cancer":"8.7","thyroid cancer":"32.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Rhabdoid":"20.5"},"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Stomach - Parietal cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"}},{"Gene":"SLC26A8","Gene synonym":[],"Ensembl":"ENSG00000112053","Gene description":"Solute carrier family 26 member 8","Uniprot":["Q96RN1"],"Chromosome":"6","Position":"35943516-36024868","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Differentiation","Ion transport","Meiosis","Spermatogenesis","Transport"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"testis":"44.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"64.2","Excitatory neurons":"15.6","Inhibitory neurons":"11.8","Late spermatids":"10.2","Spermatocytes":"51.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"neutrophil":"2.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"2.3"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Lung - Neutrophil_2","Stomach - Neutrophils","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038081"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038081":"AB_10670653"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-8"}},{"Gene":"SLC26A9","Gene synonym":[],"Ensembl":"ENSG00000174502","Gene description":"Solute carrier family 26 member 9","Uniprot":["Q7LBE3"],"Chromosome":"1","Position":"205913048-205943460","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"salivary gland":"72.4","stomach 1":"33.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Alveolar cells type 2":"34.5","Cardiomyocytes":"33.6","Gastric mucus-secreting cells":"25.6","Proximal tubular cells":"24.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"9.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"3.4","pancreatic cancer":"3.6"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Lung - Alveolar cells type 2","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051485"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA051485":"AB_2681503"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.55e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"}},{"Gene":"SLC27A3","Gene synonym":["ACSVL3","FATP3","MGC4365"],"Ensembl":"ENSG00000143554","Gene description":"Solute carrier family 27 member 3","Uniprot":["Q5K4L6"],"Chromosome":"1","Position":"153774354-153780157","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Lipid transport","Transport"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"78.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"7.4","granulocytes":"12.6","monocytes":"11.1"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"skin cancer":"18.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006935","HPA067508"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA006935":"AB_1080003","HPA067508":"AB_2685857"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.23e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.33e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"}},{"Gene":"SLC27A4","Gene synonym":["ACSVL4","FATP4"],"Ensembl":"ENSG00000167114","Gene description":"Solute carrier family 27 member 4","Uniprot":["Q6P1M0"],"Chromosome":"9","Position":"128340527-128361470","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Lipid transport","Transport"],"Molecular function":["Ligase"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"52.1","Proximal enterocytes":"112.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007293","CAB009771"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB009771":"AB_2270540","HPA007293":"AB_1857062"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.61e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-3"}},{"Gene":"SLC27A5","Gene synonym":["ACSB","ACSVL6","FACVL3","FATP5","FLJ22987","VLACSR","VLCS-H2","VLCSH2"],"Ensembl":"ENSG00000083807","Gene description":"Solute carrier family 27 member 5","Uniprot":["Q9Y2P5"],"Chromosome":"19","Position":"58479512-58512413","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Fatty acid metabolism","Lipid metabolism","Lipid transport","Transport"],"Molecular function":["Ligase","Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"21","RNA tissue specific nTPM":{"liver":"1023.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"141.5","Hepatocytes":"342.9","Late spermatids":"462.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"26","RNA cancer specific FPKM":{"liver cancer":"49.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007292","CAB056160","CAB068239"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB056160":"AB_2665590","CAB068239":"AB_2665592","HPA007292":"AB_1857064"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.57e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"}},{"Gene":"SLC28A1","Gene synonym":["CNT1"],"Ensembl":"ENSG00000156222","Gene description":"Solute carrier family 28 member 1","Uniprot":["O00337"],"Chromosome":"15","Position":"84884654-84945798","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"21","RNA tissue specific nTPM":{"intestine":"49.1","kidney":"48.2","liver":"111.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Hepatocytes":"35.3","Hofbauer cells":"45.4","Proximal enterocytes":"88.8","Proximal tubular cells":"81.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"63","RNA cancer specific FPKM":{"liver cancer":"10.9","renal cancer":"33.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Kidney cancer":"4.1"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019551","HPA056247"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles","Cytosol"],"Antibody RRID":{"HPA019551":"AB_2670187","HPA056247":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"}},{"Gene":"SLC28A2","Gene synonym":["CNT2","HCNT2","HsT17153","SPNT1"],"Ensembl":"ENSG00000137860","Gene description":"Solute carrier family 28 member 2","Uniprot":["O43868"],"Chromosome":"15","Position":"45252234-45277846","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"92.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"11.9","Distal enterocytes":"27.5","Intestinal goblet cells":"17.8","Paneth cells":"29.5","Proximal enterocytes":"42.9","Undifferentiated cells":"24.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"3.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Gastric cancer":"8.5"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046068","HPA055623"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA046068":"AB_2679523","HPA055623":"AB_2682866"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"}},{"Gene":"SLC28A3","Gene synonym":["CNT3"],"Ensembl":"ENSG00000197506","Gene description":"Solute carrier family 28 member 3","Uniprot":["Q9HAS3"],"Chromosome":"9","Position":"84275457-84340758","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"22.4","salivary gland":"12.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"11.8","Ductal cells":"27.5","Ionocytes":"15.3","Mucus glandular cells":"26.1","Thymic epithelial cells":"26.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"2.7"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023311","HPA024729"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023311":"AB_1857067","HPA024729":"AB_1857069"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.37e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"}},{"Gene":"SLC29A1","Gene synonym":["ENT1"],"Ensembl":"ENSG00000112759","Gene description":"Solute carrier family 29 member 1 (Augustine blood group)","Uniprot":["Q99808"],"Chromosome":"6","Position":"44219553-44234142","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"224.4","Extravillous trophoblasts":"245.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"26","RNA blood cell specific nTPM":{"eosinophil":"1046.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"granulocytes":"1046.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012384"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012384":"AB_1857073"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"SLC29A2","Gene synonym":["DER12","ENT2","HNP36"],"Ensembl":"ENSG00000174669","Gene description":"Solute carrier family 29 member 2","Uniprot":["Q14542"],"Chromosome":"11","Position":"66362521-66372214","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"90.8","tongue":"47.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"47.4","Skeletal myocytes":"30.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018168"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018168":"AB_1857077"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.04e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.78e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-3"}},{"Gene":"SLC29A3","Gene synonym":["ENT3","FLJ11160"],"Ensembl":"ENSG00000198246","Gene description":"Solute carrier family 29 member 3","Uniprot":["Q9BZD2"],"Chromosome":"10","Position":"71319259-71381423","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"46.7","Extravillous trophoblasts":"49.8","Hofbauer cells":"30.2","Syncytiotrophoblasts":"33.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Adipose progenitor cells","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046085","HPA054976","HPA057905"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046085":"AB_2679531","HPA054976":"AB_2682659","HPA057905":"AB_2683550"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.07e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.53e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.16e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"}},{"Gene":"SLC29A4","Gene synonym":["ENT4","FLJ34923"],"Ensembl":"ENSG00000164638","Gene description":"Solute carrier family 29 member 4","Uniprot":["Q7RTT9"],"Chromosome":"7","Position":"5274369-5306912","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"43.3","choroid plexus":"55.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"54.1","Granulosa cells":"26.6","Horizontal cells":"62.2","Inhibitory neurons":"13.9","Pancreatic endocrine cells":"20.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"39.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052829"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":["Microtubules","Cytokinetic bridge"],"Subcellular additional location":null,"Antibody RRID":{"HPA052829":"AB_2681967"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.52e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"}},{"Gene":"SLC2A1","Gene synonym":["CSE","DYT18","DYT9","GLUT","GLUT1","HTLVR"],"Ensembl":"ENSG00000117394","Gene description":"Solute carrier family 2 member 1","Uniprot":["P11166"],"Chromosome":"1","Position":"42925353-42958893","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Cataract","Disease variant","Dystonia","Epilepsy","Hereditary hemolytic anemia","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"98.7","skin 1":"79.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"813.1","Extravillous trophoblasts":"578.1","Muller glia cells":"361.2","Syncytiotrophoblasts":"2405.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002759","HPA031345","HPA058494"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002759":null,"HPA031345":"AB_2673835","HPA058494":"AB_2683734"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.65e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.39e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.55e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.05e-4"}},{"Gene":"SLC2A10","Gene synonym":["GLUT10"],"Ensembl":"ENSG00000197496","Gene description":"Solute carrier family 2 member 10","Uniprot":["O95528"],"Chromosome":"20","Position":"46709649-46736347","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"41.0","Intestinal goblet cells":"67.2","Prostatic glandular cells":"46.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"75","RNA blood cell specific nTPM":{"basophil":"20.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"75","RNA blood lineage specific nTPM":{"granulocytes":"20.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Kidney - Fibroblasts","Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041015","HPA055673"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041015":"AB_2677252","HPA055673":"AB_2682879"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"}},{"Gene":"SLC2A11","Gene synonym":["GLUT10","GLUT11"],"Ensembl":"ENSG00000133460","Gene description":"Solute carrier family 2 member 11","Uniprot":["Q9BYW1"],"Chromosome":"22","Position":"23856703-23886309","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"184.4","Rod photoreceptor cells":"213.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042960","HPA071184"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA042960":"AB_2678241","HPA071184":"AB_2686355"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.83e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.77e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"}},{"Gene":"SLC2A12","Gene synonym":["GLUT12","GLUT8"],"Ensembl":"ENSG00000146411","Gene description":"Solute carrier family 2 member 12","Uniprot":["Q8TD20"],"Chromosome":"6","Position":"133987581-134052624","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"87.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"24.0","Prostatic glandular cells":"70.2","Syncytiotrophoblasts":"40.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"prostate cancer":"18.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"21.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Breast - Breast myoepithelial cells","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031593","HPA031594"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA031593":"AB_10600810","HPA031594":"AB_2673948"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"}},{"Gene":"SLC2A13","Gene synonym":["HMIT"],"Ensembl":"ENSG00000151229","Gene description":"Solute carrier family 2 member 13","Uniprot":["Q96QE2"],"Chromosome":"12","Position":"39755025-40106089","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"22.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"499.8","Inhibitory neurons":"454.2","Oligodendrocyte precursor cells":"336.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006584","HPA061679"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA006584":"AB_1849755","HPA061679":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"}},{"Gene":"SLC2A14","Gene synonym":["GLUT14","SLC2A3P3"],"Ensembl":"ENSG00000173262","Gene description":"Solute carrier family 2 member 14","Uniprot":["Q8TDB8"],"Chromosome":"12","Position":"7812512-7891148","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Spermatogenesis","Sugar transport","Transport"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"testis":"81.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Spermatocytes":"52.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"35","RNA cancer specific FPKM":{"testis cancer":"7.1"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"4.7"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"3.7","neutrophil":"3.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"testis cancer":"35.5"},"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006539"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA006539":"AB_1078984"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.91e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"}},{"Gene":"SLC2A2","Gene synonym":["GLUT2"],"Ensembl":"ENSG00000163581","Gene description":"Solute carrier family 2 member 2","Uniprot":["P11168"],"Chromosome":"3","Position":"170996347-171026743","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"liver":"836.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"412.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"liver cancer":"105.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bladder cancer":"4.5","Kidney cancer":"7.0","liver cancer":"4.4"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010444","HPA028997","HPA069490"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010444":"AB_641068","HPA028997":"AB_2672860","HPA069490":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.63e-5"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC2A3","Gene synonym":["GLUT3"],"Ensembl":"ENSG00000059804","Gene description":"Solute carrier family 2 member 3","Uniprot":["P11169"],"Chromosome":"12","Position":"7919230-7936187","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"427.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"360.7","B-cells":"330.9","Endothelial cells":"341.7","Extravillous trophoblasts":"419.3","granulocytes":"549.7","Langerhans cells":"752.0","Schwann cells":"327.7","T-cells":"354.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"testis cancer":"107.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"166.1","neutrophil":"223.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"223.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"testis cancer":"1119.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002763","HPA006539"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002763":null,"HPA006539":"AB_1078984"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.58e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.36e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.89e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"}},{"Gene":"SLC2A4","Gene synonym":["GLUT4"],"Ensembl":"ENSG00000181856","Gene description":"Solute carrier family 2 member 4","Uniprot":["P14672"],"Chromosome":"17","Position":"7281718-7288257","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"98.8","skeletal muscle":"223.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"127.4","Skeletal myocytes":"53.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016544"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016544":"AB_629533"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"}},{"Gene":"SLC2A5","Gene synonym":["GLUT5"],"Ensembl":"ENSG00000142583","Gene description":"Solute carrier family 2 member 5","Uniprot":["P22732"],"Chromosome":"1","Position":"9035106-9088478","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"97.3","intestine":"109.1","skeletal muscle":"78.8","testis":"76.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"70.9","Microglial cells":"31.0","Paneth cells":"58.8","Proximal enterocytes":"192.4","Spermatocytes":"71.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"11.0","renal cancer":"11.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"naive B-cell":"23.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"23.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Leukemia":"43.7","lymphoma":"50.6","Myeloma":"31.8"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005449","HPA075145"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA005449":"AB_1078985","HPA075145":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.44e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"}},{"Gene":"SLC2A6","Gene synonym":["GLUT6","GLUT9","HSA011372"],"Ensembl":"ENSG00000160326","Gene description":"Solute carrier family 2 member 6","Uniprot":["Q9UGQ3"],"Chromosome":"9","Position":"133471094-133479127","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.9","lymphoid tissue":"13.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"45.0","Horizontal cells":"41.0","monocytes":"147.4","Rod photoreceptor cells":"46.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"73.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042272","CAB046014"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB046014":"AB_2270444","HPA042272":"AB_2677924"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.39e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.82e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-3"}},{"Gene":"SLC2A7","Gene synonym":["GLUT7"],"Ensembl":"ENSG00000197241","Gene description":"Solute carrier family 2 member 7","Uniprot":["Q6PXP3"],"Chromosome":"1","Position":"9003300-9026345","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"intestine":"3.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039931"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039931":"AB_10671046"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"}},{"Gene":"SLC2A8","Gene synonym":["GLUT8","GLUTX1"],"Ensembl":"ENSG00000136856","Gene description":"Solute carrier family 2 member 8","Uniprot":["Q9NY64"],"Chromosome":"9","Position":"127397138-127408424","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"131.1","Endometrial stromal cells":"86.9","Late spermatids":"322.2","Spermatocytes":"82.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"75.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"75.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011935"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA011935":"AB_1849760"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.57e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.86e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.55e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"}},{"Gene":"SLC2A9","Gene synonym":["Glut9","GLUTX","URATv1"],"Ensembl":"ENSG00000109667","Gene description":"Solute carrier family 2 member 9","Uniprot":["Q9NRM0"],"Chromosome":"4","Position":"9771153-10054936","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"29.3","liver":"21.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"49.4","Basal respiratory cells":"25.3","Proximal tubular cells":"73.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"6.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"36.9","myeloid DC":"30.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"30","RNA blood lineage specific nTPM":{"dendritic cells":"30.5","monocytes":"36.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"13.6","head and neck cancer":"12.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Kidney - Proximal tubular cells","Skin - Outer root sheath cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066229","HPA075669"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066229":"AB_2685639","HPA075669":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"}},{"Gene":"SLC30A1","Gene synonym":["ZNT1","ZRC1"],"Ensembl":"ENSG00000170385","Gene description":"Solute carrier family 30 member 1","Uniprot":["Q9Y6M5"],"Chromosome":"1","Position":"211571568-211579161","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"86.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"84.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015275","HPA049000"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA015275":"AB_1857083","HPA049000":"AB_2680593"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"}},{"Gene":"SLC30A10","Gene synonym":["DKFZp547M236","ZnT-10","ZNT8","ZRC1"],"Ensembl":"ENSG00000196660","Gene description":"Solute carrier family 30 member 10","Uniprot":["Q6XR72"],"Chromosome":"1","Position":"219685427-219958647","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Disease variant","Dystonia","Neurodegeneration","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"23.9","liver":"33.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"79.0","Early spermatids":"48.6","Hepatocytes":"130.0","Late spermatids":"39.2","Proximal enterocytes":"44.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"liver cancer":"7.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"1.7"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Liver - Hepatocytes","Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064547"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064547":"AB_2732715"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"}},{"Gene":"SLC30A2","Gene synonym":["ZNT2"],"Ensembl":"ENSG00000158014","Gene description":"Solute carrier family 30 member 2","Uniprot":["Q9BRI3"],"Chromosome":"1","Position":"26037252-26046118","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"pancreas":"99.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"30.2","Endometrial ciliated cells":"27.0","Glandular and luminal cells":"95.3","Proximal tubular cells":"26.6","Syncytiotrophoblasts":"89.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"19.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.2"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017979"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA017979":"AB_1857085"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.86e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"}},{"Gene":"SLC30A3","Gene synonym":["ZNT3"],"Ensembl":"ENSG00000115194","Gene description":"Solute carrier family 30 member 3","Uniprot":["Q99726"],"Chromosome":"2","Position":"27253684-27275817","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"22.2","epididymis":"68.5","testis":"35.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"15.9","Excitatory neurons":"15.4","Late spermatids":"34.8","Peritubular cells":"10.6","Sertoli cells":"13.8","Spermatocytes":"13.0","Spermatogonia":"9.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"1.3"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"10","RNA brain regional specific nTPM":{"amygdala":"14.5","basal ganglia":"10.3","cerebral cortex":"18.2","hippocampal formation":"22.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"7.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"amygdala":"130.7","basal ganglia":"48.2","cerebral cortex":"110.9","hippocampal formation":"69.1","white matter":"34.7"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"amygdala":"18.5","cerebral cortex":"55.5","hippocampal formation":"43.0"},"Antibody":["HPA060505","HPA067637","CAB079044"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Nucleoli","Cytosol"],"Antibody RRID":{"CAB079044":null,"HPA060505":"AB_2684296","HPA067637":"AB_2685875"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-4"}},{"Gene":"SLC30A4","Gene synonym":["ZNT4"],"Ensembl":"ENSG00000104154","Gene description":"Solute carrier family 30 member 4","Uniprot":["O14863"],"Chromosome":"15","Position":"45479606-45522755","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"prostate":"39.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"71.0","Late spermatids":"83.2","Prostatic glandular cells":"214.5","Spermatocytes":"44.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"20","RNA cancer specific FPKM":{"prostate cancer":"34.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"prostate cancer":"23.0"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.02e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"}},{"Gene":"SLC30A5","Gene synonym":["FLJ12496","FLJ12756","MGC5499","ZnT-5","ZNT5","ZNTL1","ZTL1"],"Ensembl":"ENSG00000145740","Gene description":"Solute carrier family 30 member 5","Uniprot":["Q8TAD4"],"Chromosome":"5","Position":"69093949-69131069","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035373"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA035373":"AB_10794630"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"}},{"Gene":"SLC30A6","Gene synonym":["FLJ31101","ZNT6"],"Ensembl":"ENSG00000152683","Gene description":"Solute carrier family 30 member 6","Uniprot":["Q6NXT4"],"Chromosome":"2","Position":"32165841-32224379","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055032","HPA057328"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA055032":"AB_2682677","HPA057328":"AB_2683411"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.55e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.58e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"}},{"Gene":"SLC30A7","Gene synonym":["ZNT7","ZnTL2"],"Ensembl":"ENSG00000162695","Gene description":"Solute carrier family 30 member 7","Uniprot":["Q8NEW0"],"Chromosome":"1","Position":"100896076-100981757","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018034"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA018034":"AB_1857089"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"}},{"Gene":"SLC30A8","Gene synonym":["ZnT-8","ZNT8"],"Ensembl":"ENSG00000164756","Gene description":"Solute carrier family 30 member 8","Uniprot":["Q8IWU4"],"Chromosome":"8","Position":"116950273-117176714","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"pancreas":"61.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Pancreatic endocrine cells":"142.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"28","RNA cancer specific FPKM":{"breast cancer":"10.6","pancreatic cancer":"15.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"5.5","Sarcoma":"17.7"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hippocampal formation":"4.1"},"Antibody":["HPA076165"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA076165":"AB_2732304"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-3"}},{"Gene":"SLC30A9","Gene synonym":["C4orf1","GAC63","HUEL","ZNT9"],"Ensembl":"ENSG00000014824","Gene description":"Solute carrier family 30 member 9","Uniprot":["Q6PML9"],"Chromosome":"4","Position":"41990502-42090461","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transcription","Transcription regulation","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004014"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004014":"AB_1080005"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.86e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"}},{"Gene":"SLC31A1","Gene synonym":["COPT1","CTR1","hCTR1"],"Ensembl":"ENSG00000136868","Gene description":"Solute carrier family 31 member 1","Uniprot":["O15431"],"Chromosome":"9","Position":"113221544-113264492","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Copper transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"107.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"90.7","Prostatic glandular cells":"92.4","Serous glandular cells":"91.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"20.9","intermediate monocyte":"26.8","myeloid DC":"16.3","neutrophil":"8.2","non-classical monocyte":"31.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"16.3","granulocytes":"8.2","monocytes":"31.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Liver - Hepatocytes","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013810"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013810":"AB_1857095"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.20e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.03e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"}},{"Gene":"SLC31A2","Gene synonym":["COPT2","CTR2","hCTR2"],"Ensembl":"ENSG00000136867","Gene description":"Solute carrier family 31 member 2","Uniprot":["O15432"],"Chromosome":"9","Position":"113150976-113164140","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Copper transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"parathyroid gland":"571.4","salivary gland":"409.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"95.9","Kupffer cells":"105.7","Macrophages":"100.1","monocytes":"217.7","Oligodendrocytes":"107.4","Serous glandular cells":"195.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"classical monocyte":"226.0","intermediate monocyte":"331.9","myeloid DC":"134.6","neutrophil":"355.8","non-classical monocyte":"423.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"47","RNA blood lineage specific nTPM":{"dendritic cells":"134.6","granulocytes":"355.8","monocytes":"423.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"28.0"},"RNA tissue cell type enrichment":["Colon - Macrophages","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014861","CAB080265","CAB080267"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Plasma membrane","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles","Intermediate filaments"],"Antibody RRID":{"CAB080265":null,"CAB080267":null,"HPA014861":"AB_1857098"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"}},{"Gene":"SLC32A1","Gene synonym":["bA122O1.1","VGAT","VIAAT"],"Ensembl":"ENSG00000101438","Gene description":"Solute carrier family 32 member 1","Uniprot":["Q9H598"],"Chromosome":"20","Position":"38724486-38729372","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"39.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"dendritic cells":"69.2","Horizontal cells":"64.1","Inhibitory neurons":"20.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037156","HPA058859","HPA059985"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB037156":"AB_532294","HPA058859":"AB_2683836","HPA059985":"AB_2684187"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC33A1","Gene synonym":["ACATN","AT-1","AT1","SPG42"],"Ensembl":"ENSG00000169359","Gene description":"Solute carrier family 33 member 1","Uniprot":["O00400"],"Chromosome":"3","Position":"155821024-155854456","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Cataract","Deafness","Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042430"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042430":"AB_10806238"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"}},{"Gene":"SLC34A1","Gene synonym":["NAPI-3","NPT2","NPTIIa","SLC11","SLC17A2"],"Ensembl":"ENSG00000131183","Gene description":"Solute carrier family 34 member 1","Uniprot":["Q06495"],"Chromosome":"5","Position":"177379235-177398848","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"54","RNA tissue specific nTPM":{"kidney":"155.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Proximal tubular cells":"102.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"renal cancer":"1.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051255","HPA077175"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear speckles","Plasma membrane","Mitotic spindle","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Nuclear speckles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Mitotic spindle","Cytosol"],"Antibody RRID":{"HPA051255":"AB_2681409","HPA077175":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"}},{"Gene":"SLC34A2","Gene synonym":["NAPI-3B"],"Ensembl":"ENSG00000157765","Gene description":"Solute carrier family 34 member 2","Uniprot":["O95436"],"Chromosome":"4","Position":"25648011-25678748","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"lung":"753.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 1":"680.0","Alveolar cells type 2":"1600.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"lung cancer":"252.6","ovarian cancer":"191.7","thyroid cancer":"585.2"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"2.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"62.8","ovarian cancer":"124.8","pancreatic cancer":"59.5"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Eccrine sweat gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037989","HPA066474"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA037989":"AB_10670536","HPA066474":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"}},{"Gene":"SLC34A3","Gene synonym":["FLJ38680","NPTIIc"],"Ensembl":"ENSG00000198569","Gene description":"Solute carrier family 34 member 3","Uniprot":["Q8N130"],"Chromosome":"9","Position":"137230757-137236555","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"9.7","kidney":"13.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Proximal enterocytes":"78.5","Proximal tubular cells":"22.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023776"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023776":"AB_1857102"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"}},{"Gene":"SLC35A1","Gene synonym":["CMPST","hCST"],"Ensembl":"ENSG00000164414","Gene description":"Solute carrier family 35 member A1","Uniprot":["P78382"],"Chromosome":"6","Position":"87470623-87512336","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"101.5","Inhibitory neurons":"85.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.70e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"SLC35A2","Gene synonym":["UGALT","UGAT","UGT","UGT1","UGT2","UGTL"],"Ensembl":"ENSG00000102100","Gene description":"Solute carrier family 35 member A2","Uniprot":["P78381"],"Chromosome":"X","Position":"48903180-48911958","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036087"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA036087":"AB_10604093"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.16e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.64e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.23e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"}},{"Gene":"SLC35A3","Gene synonym":[],"Ensembl":"ENSG00000117620","Gene description":"Solute carrier family 35 member A3","Uniprot":["Q9Y2D2"],"Chromosome":"1","Position":"99969351-100035634","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Autism spectrum disorder","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"178.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Gallbladder cancer":"115.0"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015253"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015253":"AB_1857106"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-2"}},{"Gene":"SLC35A4","Gene synonym":[],"Ensembl":"ENSG00000176087","Gene description":"Solute carrier family 35 member A4","Uniprot":["L0R6Q1","Q96G79"],"Chromosome":"5","Position":"140564446-140569100","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"130.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062210"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA062210":"AB_2684712"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.56e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"}},{"Gene":"SLC35A5","Gene synonym":["FLJ20730"],"Ensembl":"ENSG00000138459","Gene description":"Solute carrier family 35 member A5","Uniprot":["Q9BS91"],"Chromosome":"3","Position":"112561709-112585579","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"171.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035519","HPA057964"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA035519":"AB_10601487","HPA057964":"AB_2683566"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.10e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"}},{"Gene":"SLC35B1","Gene synonym":["UGTREL1"],"Ensembl":"ENSG00000121073","Gene description":"Solute carrier family 35 member B1","Uniprot":["P78383"],"Chromosome":"17","Position":"49700934-49709014","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048655","HPA057418"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum","Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA048655":"AB_2680481","HPA057418":"AB_2683432"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.69e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"}},{"Gene":"SLC35B2","Gene synonym":["UGTrel4"],"Ensembl":"ENSG00000157593","Gene description":"Solute carrier family 35 member B2","Uniprot":["Q8TB61"],"Chromosome":"6","Position":"44254096-44257890","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029638"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029638":"AB_10602402"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.90e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.59e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.07e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"SLC35B3","Gene synonym":["C6orf196","CGI-19","dJ453H5.1","PAPST2"],"Ensembl":"ENSG00000124786","Gene description":"Solute carrier family 35 member B3","Uniprot":["Q9H1N7"],"Chromosome":"6","Position":"8411435-8435561","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054661","HPA057801"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054661":"AB_2682561","HPA057801":"AB_2683532"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"}},{"Gene":"SLC35B4","Gene synonym":["FLJ14697","YEA4"],"Ensembl":"ENSG00000205060","Gene description":"Solute carrier family 35 member B4","Uniprot":["Q969S0"],"Chromosome":"7","Position":"134289332-134316930","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"98.8","Syncytiotrophoblasts":"89.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049779"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049779":"AB_2680878"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"}},{"Gene":"SLC35C1","Gene synonym":["FLJ11320","FUCT1"],"Ensembl":"ENSG00000181830","Gene description":"Solute carrier family 35 member C1","Uniprot":["Q96A29"],"Chromosome":"11","Position":"45804072-45813016","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"84.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"58.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064001"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA064001":"AB_2685171"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.68e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.64e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"}},{"Gene":"SLC35C2","Gene synonym":["bA394O2.1","C20orf5","CGI-15","OVCOV1"],"Ensembl":"ENSG00000080189","Gene description":"Solute carrier family 35 member C2","Uniprot":["Q9NQQ7"],"Chromosome":"20","Position":"46345980-46364458","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027011"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA027011":"AB_2672082"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.68e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"}},{"Gene":"SLC35D1","Gene synonym":["KIAA0260","UGTREL7"],"Ensembl":"ENSG00000116704","Gene description":"Solute carrier family 35 member D1","Uniprot":["Q9NTN3"],"Chromosome":"1","Position":"66999350-67054148","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"74.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"67.2","Early spermatids":"96.9","Hepatocytes":"99.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"8.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.47e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.55e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"}},{"Gene":"SLC35D2","Gene synonym":["SQV7L","UGTrel8"],"Ensembl":"ENSG00000130958","Gene description":"Solute carrier family 35 member D2","Uniprot":["Q76EJ3"],"Chromosome":"9","Position":"96313444-96383711","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"110.6","Proximal enterocytes":"71.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Endothelial cells","Stomach - Gastric mucous cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064047"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA064047":"AB_2685182"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"SLC35D3","Gene synonym":["FRCL1"],"Ensembl":"ENSG00000182747","Gene description":"Solute carrier family 35 member D3","Uniprot":["Q5M8T2"],"Chromosome":"6","Position":"136922301-136925660","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"5.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"1.8","Horizontal cells":"1.9","Ionocytes":"1.1","Pancreatic endocrine cells":"1.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"3.3","stomach cancer":"0.9"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"basal ganglia":"3.4","cerebral cortex":"1.5","hypothalamus":"5.2","midbrain":"2.1","thalamus":"5.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bile duct cancer":"1.6","colorectal cancer":"2.3","Gastric cancer":"3.5","lung cancer":"3.4","Neuroblastoma":"2.1","pancreatic cancer":"2.1"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Beta cells","Stomach - Gastric enteroendocrine cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"29.6","olfactory bulb":"8.5"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"20.1"},"Antibody":["HPA030431","HPA067497"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"HPA030431":"AB_10601716","HPA067497":"AB_2685854"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"}},{"Gene":"SLC35E1","Gene synonym":["FLJ14251"],"Ensembl":"ENSG00000127526","Gene description":"Solute carrier family 35 member E1","Uniprot":["Q96K37"],"Chromosome":"19","Position":"16549831-16572415","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"164.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016570","HPA062214"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA016570":"AB_2190214","HPA062214":"AB_2684713"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"}},{"Gene":"SLC35E2B","Gene synonym":[],"Ensembl":"ENSG00000189339","Gene description":"Solute carrier family 35 member E2B","Uniprot":["P0CK96"],"Chromosome":"1","Position":"1659529-1692795","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045641","HPA062711"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA045641":"AB_2679402","HPA062711":"AB_2684844"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.64e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.15e-4"}},{"Gene":"SLC35E3","Gene synonym":["BLOV1"],"Ensembl":"ENSG00000175782","Gene description":"Solute carrier family 35 member E3","Uniprot":["Q7Z769"],"Chromosome":"12","Position":"68746125-68793964","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"117.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049403"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049403":"AB_2680747"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.78e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"}},{"Gene":"SLC35E4","Gene synonym":[],"Ensembl":"ENSG00000100036","Gene description":"Solute carrier family 35 member E4","Uniprot":["Q6ICL7"],"Chromosome":"22","Position":"30635781-30669016","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"22.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"111.3","Late spermatids":"122.1","Spermatocytes":"44.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049558"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA049558":"AB_2680817"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-3"}},{"Gene":"SLC35F1","Gene synonym":["C6orf169","dJ230I3.1"],"Ensembl":"ENSG00000196376","Gene description":"Solute carrier family 35 member F1","Uniprot":["Q5T1Q4"],"Chromosome":"6","Position":"117907264-118317676","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"21.3","retina":"13.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Astrocytes":"368.2","Excitatory neurons":"388.3","Inhibitory neurons":"491.8","Oligodendrocyte precursor cells":"1287.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"15.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"3.3","skin cancer":"5.7"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019576"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centriolar satellite","Cytosol"],"Antibody RRID":{"HPA019576":"AB_2190216"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"}},{"Gene":"SLC35F2","Gene synonym":["FLJ13018"],"Ensembl":"ENSG00000110660","Gene description":"Solute carrier family 35 member F2","Uniprot":["Q8IXU6"],"Chromosome":"11","Position":"107790991-107928293","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"37.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"31.6","Serous glandular cells":"31.4","Suprabasal keratinocytes":"30.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048185","HPA060150"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA048185":"AB_2680304","HPA060150":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.03e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.92e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"}},{"Gene":"SLC35F3","Gene synonym":["FLJ37712"],"Ensembl":"ENSG00000183780","Gene description":"Solute carrier family 35 member F3","Uniprot":["Q8IY50"],"Chromosome":"1","Position":"233904676-234324511","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"17.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"478.1","Inhibitory neurons":"211.7","Oligodendrocyte precursor cells":"182.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"35","RNA blood cell specific nTPM":{"plasmacytoid DC":"3.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"35","RNA blood lineage specific nTPM":{"dendritic cells":"3.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Stomach - Gastric enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051327","HPA061582"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA051327":"AB_2681443","HPA061582":"AB_2684563"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"}},{"Gene":"SLC35F4","Gene synonym":["C14orf36","FLJ37712"],"Ensembl":"ENSG00000151812","Gene description":"Solute carrier family 35 member F4","Uniprot":["A4IF30"],"Chromosome":"14","Position":"57563920-57982194","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.6","retina":"6.4","seminal vesicle":"3.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Inhibitory neurons":"162.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"3.8"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043853"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043853":"AB_10963083"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"}},{"Gene":"SLC35F5","Gene synonym":["FLJ22004"],"Ensembl":"ENSG00000115084","Gene description":"Solute carrier family 35 member F5","Uniprot":["Q8WV83"],"Chromosome":"2","Position":"113705011-113756693","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034828","HPA049229"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA034828":"AB_2674350","HPA049229":"AB_2680682"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.60e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.71e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"}},{"Gene":"SLC35F6","Gene synonym":["ANT2BP","C2orf18","FLJ20555","TANGO9"],"Ensembl":"ENSG00000213699","Gene description":"Solute carrier family 35 member F6","Uniprot":["Q8N357"],"Chromosome":"2","Position":"26764284-26781231","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Macrophages","Lung - Macrophages","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034655"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA034655":"AB_10696359"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.71e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"}},{"Gene":"SLC35G1","Gene synonym":["C10orf60","FLJ33990","TMEM20"],"Ensembl":"ENSG00000176273","Gene description":"Solute carrier family 35 member G1","Uniprot":["Q2M3R5"],"Chromosome":"10","Position":"93893973-93956062","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"68.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Peritubular cells":"35.7","Proximal enterocytes":"42.7","Theca cells":"46.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"}},{"Gene":"SLC35G2","Gene synonym":["DKFZp564K2464","MGC3295","TMEM22"],"Ensembl":"ENSG00000168917","Gene description":"Solute carrier family 35 member G2","Uniprot":["Q8TBE7"],"Chromosome":"3","Position":"136818647-136855888","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"52.5","Early spermatids":"83.3","Excitatory neurons":"33.5","Inhibitory neurons":"41.4","Spermatocytes":"36.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"6.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory CD8 T-cell":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"T-cells":"1.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Kidney - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052054","HPA064728"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA052054":"AB_2681709","HPA064728":"AB_2685336"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.16e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"}},{"Gene":"SLC35G3","Gene synonym":["AMAC1","FLJ40154","TMEM21A"],"Ensembl":"ENSG00000164729","Gene description":"Solute carrier family 35 member G3","Uniprot":["Q8N808"],"Chromosome":"17","Position":"35192520-35194523","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"testis":"2.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"33.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC35G4","Gene synonym":["AMAC1L1","SLC35G4P"],"Ensembl":"ENSG00000236396","Gene description":"Solute carrier family 35 member G4","Uniprot":["P0C7Q5"],"Chromosome":"18","Position":"11609596-11610612","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"No human protein\/transcript evidence","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC35G5","Gene synonym":["AMAC","AMAC1L2"],"Ensembl":"ENSG00000177710","Gene description":"Solute carrier family 35 member G5","Uniprot":["Q96KT7"],"Chromosome":"8","Position":"11331012-11332360","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"2.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"11.1","Horizontal cells":"3.2","Late spermatids":"2.3","Rod photoreceptor cells":"4.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"}},{"Gene":"SLC35G6","Gene synonym":["AMAC1L3","TMEM21B"],"Ensembl":"ENSG00000259224","Gene description":"Solute carrier family 35 member G6","Uniprot":["P0C7Q6"],"Chromosome":"17","Position":"7481332-7483496","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"testis":"5.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"21.6","Late spermatids":"10.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"}},{"Gene":"SLC36A1","Gene synonym":["LYAAT-1","PAT1","TRAMD3"],"Ensembl":"ENSG00000123643","Gene description":"Solute carrier family 36 member 1","Uniprot":["Q7Z2H8"],"Chromosome":"5","Position":"151437046-151492379","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"76.3","parathyroid gland":"103.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"73.7","Excitatory neurons":"91.4","Inhibitory neurons":"60.8","Oligodendrocyte precursor cells":"46.7","Proximal enterocytes":"39.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"9","RNA brain regional specific nTPM":{"cerebellum":"76.3"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"21.7","classical monocyte":"8.7","neutrophil":"19.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"21.7","monocytes":"8.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035937"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035937":"AB_10672995"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.30e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"}},{"Gene":"SLC36A2","Gene synonym":["PAT2","TRAMD1","tramdorin"],"Ensembl":"ENSG00000186335","Gene description":"Solute carrier family 36 member 2","Uniprot":["Q495M3"],"Chromosome":"5","Position":"151314972-151347590","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"60","RNA tissue specific nTPM":{"kidney":"67.6","skeletal muscle":"80.2","tongue":"29.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Proximal tubular cells":"42.9","Skeletal myocytes":"18.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"renal cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Skeletal muscle - Skeletal myocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044002","HPA062229"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044002":"AB_10964214","HPA062229":"AB_2684717"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"}},{"Gene":"SLC36A3","Gene synonym":["PAT3","TRAMD2","tramdorin2"],"Ensembl":"ENSG00000186334","Gene description":"Solute carrier family 36 member 3","Uniprot":["Q495N2"],"Chromosome":"5","Position":"151276358-151303766","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"30","RNA tissue specific nTPM":{"testis":"7.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"191","RNA single cell type specific nTPM":{"Early spermatids":"41.4","Late spermatids":"119.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"}},{"Gene":"SLC36A4","Gene synonym":["FLJ38932","PAT4"],"Ensembl":"ENSG00000180773","Gene description":"Solute carrier family 36 member 4","Uniprot":["Q6YBV0"],"Chromosome":"11","Position":"93144174-93197991","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017887"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Golgi apparatus","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017887":"AB_2190238"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"}},{"Gene":"SLC37A1","Gene synonym":[],"Ensembl":"ENSG00000160190","Gene description":"Solute carrier family 37 member 1","Uniprot":["P57057"],"Chromosome":"21","Position":"42496008-42581440","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"45.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"166.4","Late spermatids":"169.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030418","CAB034154"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034154":"AB_2190373","HPA030418":"AB_10601602"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.22e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.43e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"}},{"Gene":"SLC37A2","Gene synonym":["FLJ00171"],"Ensembl":"ENSG00000134955","Gene description":"Solute carrier family 37 member 2","Uniprot":["Q8TED4"],"Chromosome":"11","Position":"125063302-125090516","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"78.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"57.4","Macrophages":"32.9","monocytes":"20.8","Serous glandular cells":"31.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"classical monocyte":"12.3","intermediate monocyte":"14.1","myeloid DC":"5.5","non-classical monocyte":"19.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"5.5","monocytes":"19.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"40.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Pancreas - Macrophages","Skeletal muscle - Macrophages","Skin - Keratinocyte (granular)","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014948"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014948":"AB_2190374"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"}},{"Gene":"SLC37A3","Gene synonym":["DKFZp761N0624"],"Ensembl":"ENSG00000157800","Gene description":"Solute carrier family 37 member 3","Uniprot":["Q8NCC5"],"Chromosome":"7","Position":"140293693-140404433","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.54e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.78e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"}},{"Gene":"SLC37A4","Gene synonym":["G6PT1","G6PT2","G6PT3","GSD1b","GSD1c","GSD1d"],"Ensembl":"ENSG00000137700","Gene description":"Solute carrier family 37 member 4","Uniprot":[],"Chromosome":"11","Position":"119024114-119030906","Protein class":["Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"139.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"177.1","Hepatocytes":"154.0","Proximal enterocytes":"267.6","Proximal tubular cells":"126.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038939","HPA038940"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA038939":"AB_2676279","HPA038940":"AB_2676280"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"}},{"Gene":"SLC38A1","Gene synonym":["ATA1","NAT2","SAT1"],"Ensembl":"ENSG00000111371","Gene description":"Solute carrier family 38 member 1","Uniprot":["Q9H2H9"],"Chromosome":"12","Position":"46183063-46270017","Protein class":["FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"374.1","Cardiomyocytes":"308.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Breast - Breast glandular cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039460","HPA052272"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039460":null,"HPA052272":"AB_2681781"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.76e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.95e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"}},{"Gene":"SLC38A10","Gene synonym":["MGC15523","PP1744"],"Ensembl":"ENSG00000157637","Gene description":"Solute carrier family 38 member 10","Uniprot":["Q9HBR0"],"Chromosome":"17","Position":"81244811-81295547","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021374","HPA023161","HPA024631"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"70000000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA021374":"AB_1853858","HPA023161":"AB_2190402","HPA024631":"AB_1853860"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.92e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.34e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"}},{"Gene":"SLC38A11","Gene synonym":["AVT2","FLJ39822"],"Ensembl":"ENSG00000169507","Gene description":"Solute carrier family 38 member 11","Uniprot":["Q08AI6"],"Chromosome":"2","Position":"164896186-164955525","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"28.7","epididymis":"38.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"32.7","Enteroendocrine cells":"137.7","Excitatory neurons":"52.7","granulocytes":"38.9","Sertoli cells":"30.4","Smooth muscle cells":"23.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"prostate cancer":"7.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"28","RNA blood cell specific nTPM":{"memory B-cell":"1.6","naive B-cell":"3.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"39","RNA blood lineage specific nTPM":{"B-cells":"3.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"12.1"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043432"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043432":"AB_10793948"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.00e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"}},{"Gene":"SLC38A2","Gene synonym":["ATA2","KIAA1382","SAT2","SNAT2"],"Ensembl":"ENSG00000134294","Gene description":"Solute carrier family 38 member 2","Uniprot":["Q96QD8"],"Chromosome":"12","Position":"46358188-46372773","Protein class":["FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"846.8","Suprabasal keratinocytes":"712.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035180","HPA069672"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA035180":"AB_10669901","HPA069672":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"}},{"Gene":"SLC38A3","Gene synonym":["G17","SN1"],"Ensembl":"ENSG00000188338","Gene description":"Solute carrier family 38 member 3","Uniprot":["Q99624"],"Chromosome":"3","Position":"50205246-50221486","Protein class":["FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Antiport","Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"331.6","retina":"172.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"85.2","Cone photoreceptor cells":"146.5","Hepatocytes":"91.4","Muller glia cells":"68.8","Rod photoreceptor cells":"110.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"140.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"2.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"6.1","liver cancer":"7.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Skeletal muscle - Skeletal myocytes","Stomach - Gastric enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031871"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":["Microtubules"],"Antibody RRID":{"HPA031871":"AB_2674080"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"}},{"Gene":"SLC38A4","Gene synonym":["ATA3","NAT3","PAAT"],"Ensembl":"ENSG00000139209","Gene description":"Solute carrier family 38 member 4","Uniprot":["Q969I6"],"Chromosome":"12","Position":"46764761-46832408","Protein class":["FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"60","RNA tissue specific nTPM":{"liver":"609.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Hepatocytes":"242.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"liver cancer":"61.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"9.3"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.37e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"}},{"Gene":"SLC38A5","Gene synonym":["JM24","SN2"],"Ensembl":"ENSG00000017483","Gene description":"Solute carrier family 38 member 5","Uniprot":["Q8WUX1"],"Chromosome":"X","Position":"48458537-48470260","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"pancreas":"237.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"179.5","Erythroid cells":"52.3","Exocrine glandular cells":"45.2","Plasma cells":"89.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"256.9"},"RNA tissue cell type enrichment":["Stomach - Chief cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047411"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA047411":"AB_10964355"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.13e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.22e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"}},{"Gene":"SLC38A6","Gene synonym":["NAT-1"],"Ensembl":"ENSG00000139974","Gene description":"Solute carrier family 38 member 6","Uniprot":["Q8IZM9"],"Chromosome":"14","Position":"60981114-61083733","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"199.2","Excitatory neurons":"97.4","Hofbauer cells":"92.0","Inhibitory neurons":"75.7","Late spermatids":"122.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018508"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Plasma membrane","Microtubules"],"Antibody RRID":{"HPA018508":"AB_2190518"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.47e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.37e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"}},{"Gene":"SLC38A7","Gene synonym":["FLJ10815"],"Ensembl":"ENSG00000103042","Gene description":"Solute carrier family 38 member 7","Uniprot":["Q9NVC3"],"Chromosome":"16","Position":"58665109-58684770","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"32.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"815.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Heart muscle - Cardiomyocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041777","HPA049428"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA041777":"AB_10796782","HPA049428":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.87e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-3"}},{"Gene":"SLC38A8","Gene synonym":[],"Ensembl":"ENSG00000166558","Gene description":"Solute carrier family 38 member 8","Uniprot":["A6NNN8"],"Chromosome":"16","Position":"84009667-84042795","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"3.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"16.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"melanoma":"6.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC38A9","Gene synonym":["FLJ90709"],"Ensembl":"ENSG00000177058","Gene description":"Solute carrier family 38 member 9","Uniprot":["Q8NBW4"],"Chromosome":"5","Position":"55625845-55773194","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"57.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"179.6","Early spermatids":"263.0","Late spermatids":"103.9","Syncytiotrophoblasts":"609.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043785","HPA061702"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA043785":"AB_10961859","HPA061702":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.24e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"}},{"Gene":"SLC39A1","Gene synonym":["ZIP1","ZIRTL"],"Ensembl":"ENSG00000143570","Gene description":"Solute carrier family 39 member 1","Uniprot":["Q9NY26"],"Chromosome":"1","Position":"153959099-153968184","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"51.6","Ductal cells":"139.3","Exocrine glandular cells":"57.9","Pancreatic endocrine cells":"60.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.83e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.26e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.12e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"}},{"Gene":"SLC39A10","Gene synonym":["DKFZp564L2123","FLJ90515","KIAA1265"],"Ensembl":"ENSG00000196950","Gene description":"Solute carrier family 39 member 10","Uniprot":["Q9ULF5"],"Chromosome":"2","Position":"195575977-195737702","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"48.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"168.5","Microglial cells":"353.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036512","HPA036513","HPA066087"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"250000","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA036512":"AB_2675165","HPA036513":"AB_10670801","HPA066087":"AB_2685613"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.46e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.39e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.23e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"}},{"Gene":"SLC39A11","Gene synonym":["C17orf26"],"Ensembl":"ENSG00000133195","Gene description":"Solute carrier family 39 member 11","Uniprot":["Q8N1S5"],"Chromosome":"17","Position":"72645949-73092712","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"199.0","Excitatory neurons":"106.2","Oligodendrocytes":"340.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Macrophages","Heart muscle - Macrophages","Liver - Hepatocytes","Lung - Macrophages","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021455"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA021455":"AB_2670710"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"}},{"Gene":"SLC39A12","Gene synonym":["FLJ30499"],"Ensembl":"ENSG00000148482","Gene description":"Solute carrier family 39 member 12","Uniprot":["Q504Y0"],"Chromosome":"10","Position":"17951839-18043292","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"choroid plexus":"353.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"33","RNA single cell type specific nTPM":{"Astrocytes":"129.4","Muller glia cells":"55.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"3.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC39A13","Gene synonym":["FLJ25785"],"Ensembl":"ENSG00000165915","Gene description":"Solute carrier family 39 member 13","Uniprot":["Q96H72"],"Chromosome":"11","Position":"47407132-47416496","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Ehlers-Danlos syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"954.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Liver - Vascular Endothelial cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043971"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043971":"AB_10959744"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.60e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.73e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"}},{"Gene":"SLC39A14","Gene synonym":["KIAA0062","NET34","ZIP14"],"Ensembl":"ENSG00000104635","Gene description":"Solute carrier family 39 member 14","Uniprot":["Q15043"],"Chromosome":"8","Position":"22367278-22434129","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Disease variant","Dystonia","Neurodegeneration","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"551.3","pancreas":"252.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"259.3","Hepatocytes":"493.6","Kupffer cells":"152.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016508","HPA056732"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Endoplasmic reticulum","Golgi apparatus","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA016508":"AB_1857148","HPA056732":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.00e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.79e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"}},{"Gene":"SLC39A2","Gene synonym":["ZIP2"],"Ensembl":"ENSG00000165794","Gene description":"Solute carrier family 39 member 2","Uniprot":["Q9NP94"],"Chromosome":"14","Position":"20999255-21001871","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"18.8","seminal vesicle":"33.2","skin 1":"37.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal prostatic cells":"41.3","Muller glia cells":"23.8","Squamous epithelial cells":"13.9","Suprabasal keratinocytes":"25.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"5.1","colorectal cancer":"3.3","head and neck cancer":"6.1","melanoma":"1.9","urothelial cancer":"6.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"3.0","head and neck cancer":"3.4"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030489","HPA073231"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytoplasmic bodies"],"Antibody RRID":{"HPA030489":"AB_10601488","HPA073231":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"}},{"Gene":"SLC39A3","Gene synonym":["ZIP3"],"Ensembl":"ENSG00000141873","Gene description":"Solute carrier family 39 member 3","Uniprot":["Q9BRY0"],"Chromosome":"19","Position":"2732204-2740028","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"100.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"289.3","Late spermatids":"430.4","Spermatocytes":"164.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042139","HPA058526"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042139":"AB_10793875","HPA058526":"AB_2683743"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.76e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"}},{"Gene":"SLC39A4","Gene synonym":["AEZ","AWMS2","ZIP4"],"Ensembl":"ENSG00000147804","Gene description":"Solute carrier family 39 member 4","Uniprot":["Q6P5W5"],"Chromosome":"8","Position":"144409742-144416844","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"88.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"399.6","Proximal tubular cells":"233.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.04e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"}},{"Gene":"SLC39A5","Gene synonym":[],"Ensembl":"ENSG00000139540","Gene description":"Solute carrier family 39 member 5","Uniprot":["Q6ZMH5"],"Chromosome":"12","Position":"56230049-56237846","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"intestine":"237.4","kidney":"110.0","liver":"171.1","pancreas":"306.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"814.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"30.6","liver cancer":"36.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"colorectal cancer":"19.1","Gastric cancer":"13.9","liver cancer":"21.7"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"1.1"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018423"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA018423":"AB_1857154"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-4"}},{"Gene":"SLC39A6","Gene synonym":["LIV-1"],"Ensembl":"ENSG00000141424","Gene description":"Solute carrier family 39 member 6","Uniprot":["Q13433"],"Chromosome":"18","Position":"36108531-36129385","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"276.1","Prostatic glandular cells":"445.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"breast cancer":"361.9","prostate cancer":"127.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042377"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA042377":"AB_2677968"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.33e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"}},{"Gene":"SLC39A7","Gene synonym":["D6S2244E","H2-KE4","HKE4","KE4","RING5","ZIP7"],"Ensembl":"ENSG00000112473","Gene description":"Solute carrier family 39 member 7","Uniprot":["Q92504"],"Chromosome":"6","Position":"33200445-33204439","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"187.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053999"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA053999":"AB_2682338"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"}},{"Gene":"SLC39A8","Gene synonym":["BIGM103"],"Ensembl":"ENSG00000138821","Gene description":"Solute carrier family 39 member 8","Uniprot":["Q9C0K1"],"Chromosome":"4","Position":"102251041-102431258","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"171.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 1":"743.2","Alveolar cells type 2":"604.2","Extravillous trophoblasts":"243.1","Thymic epithelial cells":"592.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038832","HPA038833"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038832":"AB_2676226","HPA038833":"AB_10670910"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.69e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.34e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.34e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-3"}},{"Gene":"SLC39A9","Gene synonym":["FLJ11274"],"Ensembl":"ENSG00000029364","Gene description":"Solute carrier family 39 member 9","Uniprot":["Q9NUM3"],"Chromosome":"14","Position":"69398015-69462390","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007921","HPA075390"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA007921":"AB_1080007","HPA075390":"AB_2686748"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"}},{"Gene":"SLC3A1","Gene synonym":["ATR1","CSNU1","D2H","NBAT","RBAT"],"Ensembl":"ENSG00000138079","Gene description":"Solute carrier family 3 member 1","Uniprot":["Q07837"],"Chromosome":"2","Position":"44275458-44321494","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["Cystinuria","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"136.2","kidney":"649.3","pancreas":"217.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"75.1","Glandular and luminal cells":"97.1","Proximal enterocytes":"222.9","Proximal tubular cells":"223.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"renal cancer":"61.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"15.1","Kidney cancer":"13.9","ovarian cancer":"11.9"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038360","HPA071102"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA038360":"AB_2675975","HPA071102":"AB_2732171"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.67e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-4"}},{"Gene":"SLC3A2","Gene synonym":["4F2","4F2HC","4T2HC","CD98","CD98HC","MDU1","NACAE"],"Ensembl":"ENSG00000168003","Gene description":"Solute carrier family 3 member 2","Uniprot":["P08195"],"Chromosome":"11","Position":"62856004-62888880","Protein class":["Cancer-related genes","CD markers","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"956.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Kidney - Proximal tubular cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010455","HPA017980"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010455":"AB_638288","HPA017980":"AB_2669723"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.17e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.22e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.48e-4"}},{"Gene":"SLC40A1","Gene synonym":["FPN1","HFE4","IREG1","MTP1","SLC11A3"],"Ensembl":"ENSG00000138449","Gene description":"Solute carrier family 40 member 1","Uniprot":["Q9NP59"],"Chromosome":"2","Position":"189560590-189583758","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Iron transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"2777.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"326.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"72.6","liver cancer":"52.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065634"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA065634":"AB_2685524"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"}},{"Gene":"SLC41A1","Gene synonym":["MgtE"],"Ensembl":"ENSG00000133065","Gene description":"Solute carrier family 41 member 1","Uniprot":["Q8IVJ1"],"Chromosome":"1","Position":"205789094-205813748","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Nephronophthisis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"99.3","tongue":"75.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"232.7","Theca cells":"66.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014721","HPA015138"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA014721":null,"HPA015138":"AB_1857160"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.48e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"}},{"Gene":"SLC41A2","Gene synonym":["DKFZP434K0427"],"Ensembl":"ENSG00000136052","Gene description":"Solute carrier family 41 member 2","Uniprot":["Q96JW4"],"Chromosome":"12","Position":"104802553-104958744","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"114.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"99.0","Inhibitory neurons":"91.6","Oligodendrocyte precursor cells":"52.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"myeloid DC":"4.1","plasmacytoid DC":"12.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"dendritic cells":"12.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038658"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038658":"AB_10671747"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.94e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"}},{"Gene":"SLC41A3","Gene synonym":["FLJ20473"],"Ensembl":"ENSG00000114544","Gene description":"Solute carrier family 41 member 3","Uniprot":["Q96GZ6"],"Chromosome":"3","Position":"126006357-126101561","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045847"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA045847":"AB_2679472"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.04e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"}},{"Gene":"SLC43A1","Gene synonym":["PB39","POV1","R00504"],"Ensembl":"ENSG00000149150","Gene description":"Solute carrier family 43 member 1","Uniprot":["O75387"],"Chromosome":"11","Position":"57484534-57515780","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"128.6","pancreas":"233.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"32.7","Erythroid cells":"49.7","Hepatocytes":"106.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"45.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018813","HPA018826"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Golgi apparatus","Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA018813":"AB_1857164","HPA018826":"AB_1857165"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.19e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.97e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.27e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"}},{"Gene":"SLC43A2","Gene synonym":["MGC34680"],"Ensembl":"ENSG00000167703","Gene description":"Solute carrier family 43 member 2","Uniprot":["Q8N370"],"Chromosome":"17","Position":"1569268-1628886","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"60.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cytotrophoblasts":"382.3","Syncytiotrophoblasts":"944.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"15.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021564"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021564":"AB_1857169"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.40e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"}},{"Gene":"SLC43A3","Gene synonym":["DKFZp762A227","Eeg1","FOAP-13","PRO1659","SEEEG-1"],"Ensembl":"ENSG00000134802","Gene description":"Solute carrier family 43 member 3","Uniprot":["Q8NBI5"],"Chromosome":"11","Position":"57406954-57427580","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"146.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"68.3","granulocytes":"64.2","Hofbauer cells":"74.1","Langerhans cells":"92.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"105.7","intermediate monocyte":"127.0","myeloid DC":"85.8","non-classical monocyte":"146.3","plasmacytoid DC":"85.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"85.8","monocytes":"146.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"216.0"},"RNA tissue cell type enrichment":["Colon - Endothelial cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"10.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030551","HPA077244"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA030551":"AB_10604094","HPA077244":"AB_2732335"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.97e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"}},{"Gene":"SLC44A1","Gene synonym":["CD92","CDW92","CHTL1","CTL1"],"Ensembl":"ENSG00000070214","Gene description":"Solute carrier family 44 member 1","Uniprot":["Q8WWI5"],"Chromosome":"9","Position":"105244622-105439171","Protein class":["CD markers","Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"284.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Oligodendrocytes":"2307.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064714","HPA074007"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"99000","Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA064714":"AB_2685334","HPA074007":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.49e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.85e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"}},{"Gene":"SLC44A2","Gene synonym":["CTL2"],"Ensembl":"ENSG00000129353","Gene description":"Solute carrier family 44 member 2","Uniprot":["Q8IWA5"],"Chromosome":"19","Position":"10602457-10644557","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"160.3","Extravillous trophoblasts":"270.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003228","HPA070799"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Vesicles","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA003228":"AB_1080009","HPA070799":"AB_2686314"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.01e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.71e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"}},{"Gene":"SLC44A3","Gene synonym":["CTL3","MGC45474"],"Ensembl":"ENSG00000143036","Gene description":"Solute carrier family 44 member 3","Uniprot":["Q8N4M1"],"Chromosome":"1","Position":"94820342-94895246","Protein class":["Cancer-related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Paneth cells":"49.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"MAIT T-cell":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"T-cells":"1.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"48.7"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Skeletal muscle - Fibroblasts","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"pons and medulla":"1.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047433"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047433":"AB_2680046"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.63e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"}},{"Gene":"SLC44A4","Gene synonym":["C6orf29","CTL4","DFNA72","FLJ14491","NG22","TPPT"],"Ensembl":"ENSG00000204385","Gene description":"Solute carrier family 44 member 4","Uniprot":["Q53GD3"],"Chromosome":"6","Position":"31863192-31879046","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"132.0","prostate":"83.0","stomach 1":"83.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"222.1","Distal enterocytes":"465.4","Gastric mucus-secreting cells":"191.4","Intestinal goblet cells":"261.7","Ionocytes":"217.2","Paneth cells":"187.6","Prostatic glandular cells":"326.4","Proximal enterocytes":"260.4","Respiratory ciliated cells":"403.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"222.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"27.3"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Colon - Colon enterocytes","Lung - Respiratory ciliated cells","Prostate - Prostate glandular cells","Skin - Eccrine sweat gland cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046977","HPA054176"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046977":"AB_2679887","HPA054176":"AB_2682404"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.54e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.06e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.06e-4"}},{"Gene":"SLC44A5","Gene synonym":["CTL5","MGC34032"],"Ensembl":"ENSG00000137968","Gene description":"Solute carrier family 44 member 5","Uniprot":["Q8NCS7"],"Chromosome":"1","Position":"75202131-75611116","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"10.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"92.6","Excitatory neurons":"270.1","Inhibitory neurons":"550.7","Oligodendrocyte precursor cells":"254.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047455","HPA051011"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA047455":"AB_2680054","HPA051011":"AB_2681309"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.52e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-1"}},{"Gene":"SLC45A1","Gene synonym":["DNB5"],"Ensembl":"ENSG00000162426","Gene description":"Solute carrier family 45 member 1","Uniprot":["Q9Y2W3"],"Chromosome":"1","Position":"8318114-8344167","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"11.4","Cone photoreceptor cells":"8.6","Excitatory neurons":"9.9","Horizontal cells":"13.5","Inhibitory neurons":"10.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"non-classical monocyte":"3.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"3.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"9.3"},"RNA tissue cell type enrichment":["Kidney - Podocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078818"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078818":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-3"}},{"Gene":"SLC45A2","Gene synonym":["AIM-1","MATP","OCA4"],"Ensembl":"ENSG00000164175","Gene description":"Solute carrier family 45 member 2","Uniprot":["Q9UMX9"],"Chromosome":"5","Position":"33944623-33984693","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Melanin biosynthesis","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Albinism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"1.2","skin 1":"1.0","testis":"1.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"2.6","Excitatory neurons":"4.0","Inhibitory neurons":"5.3","Late spermatids":"6.0","Melanocytes":"17.4","Oligodendrocytes":"4.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"melanoma":"47.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"76","RNA cell line specific nTPM":{"skin cancer":"133.9"},"RNA tissue cell type enrichment":["Skin - Melanocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"}},{"Gene":"SLC45A3","Gene synonym":["IPCA-2","IPCA-6","IPCA-8","PCANAP2","PCANAP6","PCANAP8","prostein"],"Ensembl":"ENSG00000158715","Gene description":"Solute carrier family 45 member 3","Uniprot":["Q96JT2"],"Chromosome":"1","Position":"205657851-205680509","Protein class":["Cancer-related genes","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"prostate":"306.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"granulocytes":"111.0","Prostatic glandular cells":"438.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"49","RNA cancer specific FPKM":{"prostate cancer":"539.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"382","RNA blood cell specific nTPM":{"basophil":"40.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"382","RNA blood lineage specific nTPM":{"granulocytes":"40.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"prostate cancer":"99.4"},"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Prostate - Prostate glandular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019073","HPA019075"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA019073":"AB_1857177","HPA019075":"AB_1857179"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.04e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.33e-5"}},{"Gene":"SLC45A4","Gene synonym":["KIAA1126"],"Ensembl":"ENSG00000022567","Gene description":"Solute carrier family 45 member 4","Uniprot":["Q5BKX6"],"Chromosome":"8","Position":"141207166-141308305","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"39.4","Cone photoreceptor cells":"44.8","Endometrial ciliated cells":"50.9","Gastric mucus-secreting cells":"41.7","Glandular and luminal cells":"84.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"eosinophil":"8.3","neutrophil":"7.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"granulocytes":"8.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023154"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA023154":"AB_2191204"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.73e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"}},{"Gene":"SLC46A1","Gene synonym":["HCP1","MGC9564","PCFT"],"Ensembl":"ENSG00000076351","Gene description":"Solute carrier family 46 member 1","Uniprot":["Q96NT5"],"Chromosome":"17","Position":"28394642-28407197","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"93.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"26.4","Hofbauer cells":"23.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011614"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB011614":"AB_2270597"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.62e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"SLC46A2","Gene synonym":["Ly110","TSCOT"],"Ensembl":"ENSG00000119457","Gene description":"Solute carrier family 46 member 2","Uniprot":["Q9BY10"],"Chromosome":"9","Position":"112878920-112890876","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"16.5","lung":"10.4","lymphoid tissue":"16.0","skin 1":"24.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"24.2","Endometrial ciliated cells":"14.8","Glandular and luminal cells":"6.5","Hofbauer cells":"5.2","Kupffer cells":"11.5","Late spermatids":"5.3","Macrophages":"5.5","monocytes":"6.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"1.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"24.6","intermediate monocyte":"12.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"24.6"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Keratinocyte (granular)","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020098"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA020098":"AB_2670363"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"}},{"Gene":"SLC46A3","Gene synonym":["DKFZp686A1775","FLJ42613"],"Ensembl":"ENSG00000139508","Gene description":"Solute carrier family 46 member 3","Uniprot":["Q7Z3Q1"],"Chromosome":"13","Position":"28700064-28718970","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"76.0","liver":"96.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"51.5","Proximal enterocytes":"115.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039930"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA039930":"AB_10673263"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.09e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"}},{"Gene":"SLC47A1","Gene synonym":["FLJ10847","MATE1"],"Ensembl":"ENSG00000142494","Gene description":"Solute carrier family 47 member 1","Uniprot":["Q96FL8"],"Chromosome":"17","Position":"19495385-19579034","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"127.3","kidney":"100.3","liver":"103.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Granulosa cells":"182.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"37.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"eosinophil":"12.2","plasmacytoid DC":"6.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"6.6","granulocytes":"12.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021987"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021987":"AB_1857185"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.54e-8"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.88e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.06e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"}},{"Gene":"SLC47A2","Gene synonym":["FLJ31196","MATE2","MATE2-K"],"Ensembl":"ENSG00000180638","Gene description":"Solute carrier family 47 member 2","Uniprot":["Q86VL8"],"Chromosome":"17","Position":"19678288-19718979","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"22.3","choroid plexus":"39.6","kidney":"55.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"22.6","Proximal tubular cells":"81.9","Skeletal myocytes":"15.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.6","renal cancer":"4.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"4.1","Kidney cancer":"5.1"},"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.95e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"}},{"Gene":"SLC48A1","Gene synonym":["FLJ20489","hHRG-1","HRG1"],"Ensembl":"ENSG00000211584","Gene description":"Solute carrier family 48 member 1","Uniprot":["Q6P1K1"],"Chromosome":"12","Position":"47753916-47782751","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"135.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"94.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065396","HPA073994"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA065396":null,"HPA073994":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.27e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.39e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.34e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"}},{"Gene":"SLC49A3","Gene synonym":["FLJ22269","LP2561","MFSD7"],"Ensembl":"ENSG00000169026","Gene description":"Solute carrier family 49 member 3","Uniprot":["Q6UXD7"],"Chromosome":"4","Position":"681829-689271","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"35.3","Extravillous trophoblasts":"39.2","Hofbauer cells":"34.7","Late spermatids":"36.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043593"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043593":"AB_10959611"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.66e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"}},{"Gene":"SLC49A4","Gene synonym":["DIRC2","FLJ14784","RCC4"],"Ensembl":"ENSG00000138463","Gene description":"Solute carrier family 49 member 4","Uniprot":["Q96SL1"],"Chromosome":"3","Position":"122795069-122881139","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"276.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072579"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA072579":"AB_2686536"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.81e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.81e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"}},{"Gene":"SLC4A1","Gene synonym":["AE1","CD233","DI","EPB3","FR","RTA1A","SW","WD","WR"],"Ensembl":"ENSG00000004939","Gene description":"Solute carrier family 4 member 1 (Diego blood group)","Uniprot":["P02730"],"Chromosome":"17","Position":"44248390-44268141","Protein class":["Blood group antigen proteins","CD markers","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Ion transport","Transport"],"Molecular function":["Blood group antigen"],"Disease involvement":["Disease variant","Elliptocytosis","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"407.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"289","RNA single cell type specific nTPM":{"Erythroid cells":"900.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"91","RNA cancer specific FPKM":{"renal cancer":"16.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"3.0","neutrophil":"2.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"21","RNA cell line specific nTPM":{"Leukemia":"15.9"},"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Liver - Erythroid cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015584","CAB034438","HPA063911"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"22000000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034438":"AB_2123479","HPA015584":"AB_1844824","HPA063911":"AB_2685151"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"}},{"Gene":"SLC4A10","Gene synonym":["NBCn2","NCBE"],"Ensembl":"ENSG00000144290","Gene description":"Solute carrier family 4 member 10","Uniprot":["Q6U841"],"Chromosome":"2","Position":"161424332-161985282","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"21.3","choroid plexus":"121.4","retina":"34.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"595.7","Inhibitory neurons":"548.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.3"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"21.3"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"MAIT T-cell":"63.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"65","RNA blood lineage specific nTPM":{"T-cells":"63.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"1.2","lymphoma":"1.3","prostate cancer":"2.0"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034755","HPA076725"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034755":"AB_10670296","HPA076725":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"}},{"Gene":"SLC4A11","Gene synonym":["BTR1","CDPD1","CHED2","dJ794I6.2","FECD4","NaBC1"],"Ensembl":"ENSG00000088836","Gene description":"Solute carrier family 4 member 11","Uniprot":["Q8NBS3"],"Chromosome":"20","Position":"3227417-3239559","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Ion transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Corneal dystrophy","Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"51.3","salivary gland":"54.0","thyroid gland":"60.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"28.6","Collecting duct cells":"102.4","Ionocytes":"68.1","Respiratory ciliated cells":"54.4","Salivary duct cells":"39.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Lung - Respiratory ciliated cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018120","HPA058377"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA018120":"AB_1857186","HPA058377":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.03e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"}},{"Gene":"SLC4A2","Gene synonym":["AE2","BND3L","EPB3L1","HKB3","NBND3"],"Ensembl":"ENSG00000164889","Gene description":"Solute carrier family 4 member 2","Uniprot":["P04920"],"Chromosome":"7","Position":"151057210-151076526","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Antiport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"choroid plexus":"492.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"94.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019339"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear speckles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nuclear speckles","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA019339":"AB_1844825"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.04e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.26e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"}},{"Gene":"SLC4A3","Gene synonym":["AE3","SLC2C"],"Ensembl":"ENSG00000114923","Gene description":"Solute carrier family 4 member 3","Uniprot":["P48751"],"Chromosome":"2","Position":"219627394-219641980","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Antiport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"heart muscle":"283.1","ovary":"124.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"176.2","Granulosa cells":"42.6","Horizontal cells":"138.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"13.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"34","RNA blood cell specific nTPM":{"myeloid DC":"1.4","plasmacytoid DC":"5.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"54","RNA blood lineage specific nTPM":{"dendritic cells":"5.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063498"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA063498":"AB_2685025"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.12e-4"}},{"Gene":"SLC4A4","Gene synonym":["hhNMC","HNBC1","NBC1","NBC2","pNBC","SLC4A5"],"Ensembl":"ENSG00000080493","Gene description":"Solute carrier family 4 member 4","Uniprot":["Q9Y6R1"],"Chromosome":"4","Position":"71062667-71572087","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"119.5","pancreas":"260.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"793.6","Cholangiocytes":"142.4","Distal enterocytes":"234.7","Ductal cells":"143.7","Proximal tubular cells":"174.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"23.9","pancreatic cancer":"22.5","prostate cancer":"47.4","renal cancer":"19.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"19.6","prostate cancer":"11.8"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Adipocytes (Breast)","Kidney - Proximal tubular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022493","HPA035628","HPA035629","HPA079220"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022493":null,"HPA035628":"AB_2674708","HPA035629":"AB_2674709","HPA079220":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.69e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"}},{"Gene":"SLC4A5","Gene synonym":["NBC4"],"Ensembl":"ENSG00000188687","Gene description":"Solute carrier family 4 member 5","Uniprot":["Q9BY07"],"Chromosome":"2","Position":"74216242-74343414","Protein class":["Cancer-related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"73.4","retina":"42.0","thyroid gland":"26.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"15.5","Bipolar cells":"22.7","Cone photoreceptor cells":"20.7","Horizontal cells":"42.3","Oligodendrocytes":"29.3","Rod photoreceptor cells":"46.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"thyroid cancer":"3.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"4.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"1.6","hippocampal formation":"5.2","pons and medulla":"6.5","thalamus":"3.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036621"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036621":"AB_10696779"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-4"}},{"Gene":"SLC4A7","Gene synonym":["NBC3","SBC2","SLC4A6"],"Ensembl":"ENSG00000033867","Gene description":"Solute carrier family 4 member 7","Uniprot":["Q9Y6M7"],"Chromosome":"3","Position":"27372721-27484420","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"57.6","retina":"72.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"477.4","Rod photoreceptor cells":"712.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022494","HPA035857"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Focal adhesion sites","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Focal adhesion sites","Cytosol"],"Antibody RRID":{"CAB022494":null,"HPA035857":"AB_10795135"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.91e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"}},{"Gene":"SLC4A8","Gene synonym":["NBC3"],"Ensembl":"ENSG00000050438","Gene description":"Solute carrier family 4 member 8","Uniprot":["Q2Y0W8"],"Chromosome":"12","Position":"51391317-51515763","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"24.1","pituitary gland":"17.9","retina":"11.1","testis":"11.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"83.5","Cone photoreceptor cells":"63.8","Excitatory neurons":"113.2","Horizontal cells":"108.9","Inhibitory neurons":"125.1","Oligodendrocytes":"235.0","Spermatocytes":"87.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"breast cancer":"1.7","glioma":"2.7","testis cancer":"4.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"24.9"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Pancreas - Beta cells","Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077895"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA077895":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"}},{"Gene":"SLC4A9","Gene synonym":["AE4"],"Ensembl":"ENSG00000113073","Gene description":"Solute carrier family 4 member 9","Uniprot":["Q96Q91"],"Chromosome":"5","Position":"140360194-140375141","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Anion exchange","Antiport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"kidney":"35.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"3.9","Distal tubular cells":"3.1","Excitatory neurons":"2.4","Inhibitory neurons":"2.3","Oligodendrocyte precursor cells":"1.4","Oligodendrocytes":"6.1","Spermatocytes":"1.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"renal cancer":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Intercalated cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051307"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA051307":"AB_2681434"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"}},{"Gene":"SLC50A1","Gene synonym":["HsSWEET1","RAG1AP1","RP11-540D14.5","RZPDo834D038D","SCP","slv","SWEET1"],"Ensembl":"ENSG00000169241","Gene description":"Solute carrier family 50 member 1","Uniprot":["Q9BRV3"],"Chromosome":"1","Position":"155135344-155138857","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"150.0","Intestinal goblet cells":"173.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018095"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018095":"AB_1856048"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.88e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"}},{"Gene":"SLC51A","Gene synonym":["OSTalpha"],"Ensembl":"ENSG00000163959","Gene description":"Solute carrier family 51 subunit alpha","Uniprot":["Q86UW1"],"Chromosome":"3","Position":"196211487-196243178","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Intrahepatic cholestasis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"intestine":"64.5","liver":"71.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"55.5","Hepatocytes":"44.6","Leydig cells":"63.6","Peritubular cells":"104.3","Proximal enterocytes":"318.8","Sertoli cells":"63.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"liver cancer":"15.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045488"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045488":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.54e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-5"}},{"Gene":"SLC51B","Gene synonym":["OSTbeta"],"Ensembl":"ENSG00000186198","Gene description":"Solute carrier family 51 subunit beta","Uniprot":["Q86UW2"],"Chromosome":"15","Position":"65045387-65053397","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"41.8","intestine":"107.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Distal enterocytes":"330.7","Proximal enterocytes":"800.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"9.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"13.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Breast - Smooth muscle cells","Colon - Colon enterocytes","Kidney - Proximal tubular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008398","HPA008533"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA008398":null,"HPA008533":"AB_1854824"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.46e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"}},{"Gene":"SLC52A1","Gene synonym":["FLJ10060","GPCR42","GPR172B","hRFT1","PAR2","RFVT1"],"Ensembl":"ENSG00000132517","Gene description":"Solute carrier family 52 member 1","Uniprot":["Q9NWF4"],"Chromosome":"17","Position":"5032600-5052009","Protein class":["Disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Transport"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"intestine":"35.8","placenta":"18.4","skin 1":"11.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"842.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"cervical cancer":"9.3","Esophageal cancer":"5.9","head and neck cancer":"4.5"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.54e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"}},{"Gene":"SLC52A2","Gene synonym":["D15Ertd747e","FLJ11856","GPCR41","GPR172A","hRFT3","PAR1","RFVT2"],"Ensembl":"ENSG00000185803","Gene description":"Solute carrier family 52 member 2","Uniprot":["Q9HAB3"],"Chromosome":"8","Position":"144333957-144361286","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Deafness","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063036"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063036":"AB_2684928"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.55e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.04e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"SLC52A3","Gene synonym":["bA371L19.1","C20orf54","hRFT2","RFVT3"],"Ensembl":"ENSG00000101276","Gene description":"Solute carrier family 52 member 3","Uniprot":["Q9NQ40"],"Chromosome":"20","Position":"760080-776015","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"19.2","testis":"40.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"21.7","Cytotrophoblasts":"33.0","Glandular and luminal cells":"22.7","Proximal enterocytes":"42.2","Syncytiotrophoblasts":"55.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"19.8"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skeletal muscle - Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049391","HPA059078"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049391":"AB_2680743","HPA059078":"AB_2732630"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.51e-6"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"SLC5A1","Gene synonym":["D22S675","NAGT","SGLT1"],"Ensembl":"ENSG00000100170","Gene description":"Solute carrier family 5 member 1","Uniprot":["P13866"],"Chromosome":"22","Position":"32043261-32113029","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Sugar transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"528.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"760.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"20.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bile duct cancer":"3.2","colorectal cancer":"7.7","Gastric cancer":"2.5"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Heart muscle - Cardiomyocytes","Kidney - Ascending Loop of Henle cells","Liver - Cholangiocyte","Lung - Alveolar cells type 1","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"26","RNA mouse brain regional specific nTPM":{"cerebellum":"7.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015467","HPA051805","HPA055106"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nuclear membrane","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nuclear membrane","Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB015467":null,"HPA051805":"AB_2681618","HPA055106":"AB_2682695"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.59e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.97e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"}},{"Gene":"SLC5A10","Gene synonym":["SGLT5"],"Ensembl":"ENSG00000154025","Gene description":"Solute carrier family 5 member 10","Uniprot":["A0PJK1"],"Chromosome":"17","Position":"18950345-19022595","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"kidney":"41.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"33.8","Proximal tubular cells":"50.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"renal cancer":"6.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"intermediate monocyte":"1.8","non-classical monocyte":"4.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"monocytes":"4.8"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052014"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052014":"AB_2681694"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"}},{"Gene":"SLC5A11","Gene synonym":["KST1","SGLT6","SMIT2"],"Ensembl":"ENSG00000158865","Gene description":"Solute carrier family 5 member 11","Uniprot":["Q8WWX8"],"Chromosome":"16","Position":"24845841-24911628","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Ion transport","Sodium transport","Sugar transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"43.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Oligodendrocytes":"639.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"1.1"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035331"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA035331":"AB_10601489"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"}},{"Gene":"SLC5A12","Gene synonym":["MGC52019","SMCT2"],"Ensembl":"ENSG00000148942","Gene description":"Solute carrier family 5 member 12","Uniprot":["Q1EHB4"],"Chromosome":"11","Position":"26667020-26723427","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"47.7","intestine":"30.1","kidney":"171.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"31","RNA single cell type specific nTPM":{"Proximal enterocytes":"250.8","Proximal tubular cells":"151.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"26","RNA cancer specific FPKM":{"renal cancer":"9.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"3.3"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060904"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA060904":"AB_2684385"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"}},{"Gene":"SLC5A2","Gene synonym":["SGLT2"],"Ensembl":"ENSG00000140675","Gene description":"Solute carrier family 5 member 2","Uniprot":["P31639"],"Chromosome":"16","Position":"31483002-31490860","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Sugar transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"kidney":"54.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"59.6","Late spermatids":"144.7","Proximal tubular cells":"114.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041603"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041603":"AB_10960540"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"}},{"Gene":"SLC5A3","Gene synonym":["SMIT","SMIT1"],"Ensembl":"ENSG00000198743","Gene description":"Solute carrier family 5 member 3","Uniprot":["P53794"],"Chromosome":"21","Position":"34073578-34106260","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"96.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"126.0","Granulosa cells":"148.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"22.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029791"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA029791":"AB_10601892"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.98e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.72e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"}},{"Gene":"SLC5A4","Gene synonym":["DJ90G24.4","SAAT1","SGLT3"],"Ensembl":"ENSG00000100191","Gene description":"Solute carrier family 5 member 4","Uniprot":["Q9NY91"],"Chromosome":"22","Position":"32218464-32255347","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"19.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Excitatory neurons":"27.7","Inhibitory neurons":"20.0","Microglial cells":"31.0","Oligodendrocyte precursor cells":"9.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"melanoma":"7.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"skin cancer":"26.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"}},{"Gene":"SLC5A5","Gene synonym":["NIS"],"Ensembl":"ENSG00000105641","Gene description":"Solute carrier family 5 member 5","Uniprot":["Q92911"],"Chromosome":"19","Position":"17871945-17895174","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Congenital hypothyroidism","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"choroid plexus":"163.3","salivary gland":"64.4","stomach 1":"58.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"38","RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"219.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"3.7"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"5.6","hippocampal formation":"10.6","thalamus":"3.3"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022364","HPA049055"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022364":null,"HPA049055":"AB_2680614"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"}},{"Gene":"SLC5A6","Gene synonym":["SMVT"],"Ensembl":"ENSG00000138074","Gene description":"Solute carrier family 5 member 6","Uniprot":["Q9Y289"],"Chromosome":"2","Position":"27199587-27212958","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"104.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"122.3","Extravillous trophoblasts":"107.9","Syncytiotrophoblasts":"271.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036958"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA036958":"AB_10672343"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.60e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"}},{"Gene":"SLC5A7","Gene synonym":["CHT1","hCHT"],"Ensembl":"ENSG00000115665","Gene description":"Solute carrier family 5 member 7","Uniprot":["Q9GZV3"],"Chromosome":"2","Position":"107986523-108013994","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Neurotransmitter biosynthesis","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"32.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"2.3","Bipolar cells":"1.5","Club cells":"1.7","Melanocytes":"1.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"2.8"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"basal ganglia":"23.1","hypothalamus":"9.0","midbrain":"9.4","pons and medulla":"14.4","thalamus":"6.2"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"20.4","pons":"26.5","spinal cord":"46.7"},"Antibody":["HPA046105"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Cell Junctions","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Cell Junctions","Intermediate filaments"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA046105":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"}},{"Gene":"SLC5A8","Gene synonym":["AIT"],"Ensembl":"ENSG00000256870","Gene description":"Solute carrier family 5 member 8","Uniprot":["Q8N695"],"Chromosome":"12","Position":"101155493-101210238","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"cervix":"20.3","kidney":"5.6","thyroid gland":"15.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"12.5","Basal respiratory cells":"10.8","Early spermatids":"10.4","Enteroendocrine cells":"24.1","Excitatory neurons":"14.3","Inhibitory neurons":"16.9","Ionocytes":"25.8","Prostatic glandular cells":"13.7","Proximal tubular cells":"22.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"breast cancer":"2.7","renal cancer":"7.6","thyroid cancer":"5.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"breast cancer":"1.1"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.04e-6"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.97e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC5A9","Gene synonym":["SGLT4"],"Ensembl":"ENSG00000117834","Gene description":"Solute carrier family 5 member 9","Uniprot":["Q2M3M2"],"Chromosome":"1","Position":"48222685-48248644","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"43.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Proximal enterocytes":"75.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"4.1","renal cancer":"3.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"liver cancer":"3.4"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Skin - Outer root sheath cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050263"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA050263":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.84e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"}},{"Gene":"SLC66A1","Gene synonym":["FLJ20320","LAAT-1","LAAT1","PQLC2"],"Ensembl":"ENSG00000040487","Gene description":"Solute carrier family 66 member 1","Uniprot":["Q6ZP29"],"Chromosome":"1","Position":"19312326-19329300","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"33.6","Syncytiotrophoblasts":"69.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057810"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA057810":"AB_2683535"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.64e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"}},{"Gene":"SLC66A2","Gene synonym":["FLJ22378","PQLC1"],"Ensembl":"ENSG00000122490","Gene description":"Solute carrier family 66 member 2","Uniprot":["Q8N2U9"],"Chromosome":"18","Position":"79902420-79951657","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"185.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"155.3","Late spermatids":"178.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051666"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA051666":"AB_2681567"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"}},{"Gene":"SLC66A3","Gene synonym":["C2orf22","MGC33602","PQLC3"],"Ensembl":"ENSG00000162976","Gene description":"Solute carrier family 66 member 3","Uniprot":["Q8N755"],"Chromosome":"2","Position":"11155198-11178870","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"138.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"72.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061607"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA061607":"AB_2797264"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"}},{"Gene":"SLC6A1","Gene synonym":["GABATHG","GABATR","GAT1"],"Ensembl":"ENSG00000157103","Gene description":"Solute carrier family 6 member 1","Uniprot":["P30531"],"Chromosome":"3","Position":"10992186-11039247","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"71.3","liver":"87.3","retina":"37.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"214.1","Horizontal cells":"153.8","Inhibitory neurons":"323.7","Microglial cells":"105.8","Oligodendrocyte precursor cells":"124.7","Oligodendrocytes":"101.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"16","RNA cancer specific FPKM":{"glioma":"16.1","liver cancer":"24.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013341","CAB022293"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022293":null,"HPA013341":"AB_1849509"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.20e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.05e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"}},{"Gene":"SLC6A11","Gene synonym":["GAT3"],"Ensembl":"ENSG00000132164","Gene description":"Solute carrier family 6 member 11","Uniprot":["P48066"],"Chromosome":"3","Position":"10816201-10940714","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"153.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"82.6","Excitatory neurons":"13.5","Horizontal cells":"21.1","Inhibitory neurons":"25.0","Muller glia cells":"23.0","Oligodendrocyte precursor cells":"22.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"7.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"6.9"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037981"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA037981":"AB_10671383"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"}},{"Gene":"SLC6A12","Gene synonym":["BGT-1"],"Ensembl":"ENSG00000111181","Gene description":"Solute carrier family 6 member 12","Uniprot":["P48065"],"Chromosome":"12","Position":"190077-214570","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"35.2","kidney":"36.0","liver":"81.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"37.4","Glandular and luminal cells":"8.5","Hepatocytes":"18.7","Oligodendrocytes":"8.6","Sertoli cells":"8.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"8.8","renal cancer":"11.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"50","RNA blood cell specific nTPM":{"classical monocyte":"5.7","intermediate monocyte":"5.7","myeloid DC":"2.4","neutrophil":"3.0","non-classical monocyte":"7.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"45","RNA blood lineage specific nTPM":{"dendritic cells":"2.4","granulocytes":"3.0","monocytes":"7.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"liver cancer":"2.3","ovarian cancer":"6.3","testis cancer":"2.9","thyroid cancer":"3.0","Uterine cancer":"5.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034973"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA034973":"AB_10610427"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.70e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-4"}},{"Gene":"SLC6A13","Gene synonym":["GAT2"],"Ensembl":"ENSG00000010379","Gene description":"Solute carrier family 6 member 13","Uniprot":["Q9NSD5"],"Chromosome":"12","Position":"220621-262873","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"kidney":"153.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Proximal tubular cells":"247.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"renal cancer":"32.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"2.4"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036449","HPA052726"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Nucleoli","Cytosol"],"Antibody RRID":{"HPA036449":"AB_2675130","HPA052726":"AB_2681927"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"}},{"Gene":"SLC6A14","Gene synonym":[],"Ensembl":"ENSG00000268104","Gene description":"Solute carrier family 6 member 14","Uniprot":["Q9UN76"],"Chromosome":"X","Position":"116436606-116461458","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"16.0","salivary gland":"20.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"183.9","Basal respiratory cells":"111.6","Club cells":"169.1","Ionocytes":"280.1","Mucus glandular cells":"108.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"pancreatic cancer":"11.2"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003193"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA003193":"AB_2190122"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.74e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"}},{"Gene":"SLC6A15","Gene synonym":["FLJ10316","hv7-3","NTT73","SBAT1","V7-3"],"Ensembl":"ENSG00000072041","Gene description":"Solute carrier family 6 member 15","Uniprot":["Q9H2J7"],"Chromosome":"12","Position":"84859491-84913629","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Ion transport","Neurotransmitter transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"21.9","retina":"15.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"27.5","Bipolar cells":"35.5","Excitatory neurons":"62.9","Horizontal cells":"39.7","Inhibitory neurons":"56.0","Melanocytes":"74.9","Oligodendrocytes":"44.2","Rod photoreceptor cells":"28.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"head and neck cancer":"2.2","melanoma":"7.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"38.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008609"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA008609":"AB_1857190"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-3"}},{"Gene":"SLC6A16","Gene synonym":["NTT5"],"Ensembl":"ENSG00000063127","Gene description":"Solute carrier family 6 member 16","Uniprot":["Q9GZN6"],"Chromosome":"19","Position":"49289638-49325215","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"94.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"142.2","Late spermatids":"48.8","Spermatocytes":"128.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"18.6"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076812"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA076812":"AB_2686816"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"}},{"Gene":"SLC6A17","Gene synonym":[],"Ensembl":"ENSG00000197106","Gene description":"Solute carrier family 6 member 17","Uniprot":["Q9H1V8"],"Chromosome":"1","Position":"110150494-110202202","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"52.9","pituitary gland":"25.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Excitatory neurons":"59.7","Horizontal cells":"30.1","Inhibitory neurons":"58.0","Melanocytes":"41.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"melanoma":"17.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"6.1"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Beta cells","Skin - Melanocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008043","HPA008044"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA008043":null,"HPA008044":"AB_1857192"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"}},{"Gene":"SLC6A18","Gene synonym":["FLJ31236","Xtrp2"],"Ensembl":"ENSG00000164363","Gene description":"Solute carrier family 6 member 18","Uniprot":["Q96N87"],"Chromosome":"5","Position":"1225381-1246189","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"76","RNA tissue specific nTPM":{"kidney":"8.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Proximal tubular cells":"32.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"44","RNA cancer specific FPKM":{"renal cancer":"4.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011885"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011885":"AB_1857198"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC6A19","Gene synonym":[],"Ensembl":"ENSG00000174358","Gene description":"Solute carrier family 6 member 19","Uniprot":["Q695T7"],"Chromosome":"5","Position":"1201595-1225111","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"35","RNA tissue specific nTPM":{"intestine":"142.4","kidney":"88.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Proximal enterocytes":"521.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"renal cancer":"7.9","stomach cancer":"5.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"5.8","liver cancer":"5.9"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037415","HPA043207"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037415":"AB_10672346","HPA043207":"AB_2678363"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC6A2","Gene synonym":["NAT1","NET","NET1","SLC6A5"],"Ensembl":"ENSG00000103546","Gene description":"Solute carrier family 6 member 2","Uniprot":["P23975"],"Chromosome":"16","Position":"55655604-55706192","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"149.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"3.5","Extravillous trophoblasts":"9.5","Late spermatids":"4.8","Spermatocytes":"8.4","Syncytiotrophoblasts":"5.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"1.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"10","RNA brain regional specific nTPM":{"pons":"149.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"54","RNA cell line specific nTPM":{"Neuroblastoma":"104.8"},"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"pons and medulla":"7.8"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"19","RNA pig brain regional specific nTPM":{"pons":"13.8"},"Antibody":["HPA004057","HPA076311","CAB078195"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"CAB078195":"AB_2665806","HPA004057":"AB_1080012","HPA076311":"AB_2732307"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"}},{"Gene":"SLC6A20","Gene synonym":["IMINO","SIT1","XT3","Xtrp3"],"Ensembl":"ENSG00000163817","Gene description":"Solute carrier family 6 member 20","Uniprot":["Q9NP91"],"Chromosome":"3","Position":"45755449-45796536","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"choroid plexus":"59.2","intestine":"24.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"70.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"4.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bile duct cancer":"5.2","colorectal cancer":"14.6","Gastric cancer":"11.2","pancreatic cancer":"8.0"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"}},{"Gene":"SLC6A3","Gene synonym":["DAT","DAT1"],"Ensembl":"ENSG00000142319","Gene description":"Solute carrier family 6 member 3","Uniprot":["Q01959"],"Chromosome":"5","Position":"1392794-1445440","Protein class":["Disease related genes","FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Dystonia","FDA approved drug targets","Neurodegeneration","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"73","RNA tissue specific nTPM":{"brain":"60.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Serous glandular cells":"2.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"renal cancer":"25.7"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"26","RNA brain regional specific nTPM":{"midbrain":"60.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Kidney cancer":"3.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"8","RNA mouse brain regional specific nTPM":{"midbrain":"80.6","thalamus":"29.0"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"152","RNA pig brain regional specific nTPM":{"midbrain":"302.6"},"Antibody":["HPA012763","HPA013602","CAB016249","CAB078172"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB016249":"AB_627402","CAB078172":"AB_2665810","HPA012763":"AB_2732405","HPA013602":"AB_1847484"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.40e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"}},{"Gene":"SLC6A4","Gene synonym":["5-HTT","HTT","OCD1","SERT1"],"Ensembl":"ENSG00000108576","Gene description":"Solute carrier family 6 member 4","Uniprot":["P31645"],"Chromosome":"17","Position":"30194319-30236002","Protein class":["FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"232.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Cytotrophoblasts":"120.7","Proximal enterocytes":"101.8","Syncytiotrophoblasts":"96.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"2.3"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"11","RNA brain regional specific nTPM":{"midbrain":"232.0","pons":"86.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.8","liver cancer":"1.7"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"midbrain":"58.4"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"midbrain":"38.9","pons":"29.1"},"Antibody":["HPA054723","HPA071354","HPA074728"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA054723":null,"HPA071354":null,"HPA074728":"AB_2686708"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"}},{"Gene":"SLC6A5","Gene synonym":["GLYT2","NET1"],"Ensembl":"ENSG00000165970","Gene description":"Solute carrier family 6 member 5","Uniprot":["Q9Y345"],"Chromosome":"11","Position":"20599594-20659285","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"brain":"22.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Late spermatids":"72.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"medulla oblongata":"22.2","pons":"20.0","spinal cord":"7.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Uterine cancer":"1.9"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"pons and medulla":"49.3"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"medulla oblongata":"30.5","spinal cord":"18.3"},"Antibody":["CAB079052"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB079052":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC6A6","Gene synonym":["TAUT"],"Ensembl":"ENSG00000131389","Gene description":"Solute carrier family 6 member 6","Uniprot":["P31641"],"Chromosome":"3","Position":"14402576-14489349","Protein class":["Disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"68.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"465.3","Rod photoreceptor cells":"618.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"59.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"59.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015028","HPA016488"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Cell Junctions","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015028":"AB_1857200","HPA016488":"AB_1857202"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.22e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.75e-8"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.78e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"}},{"Gene":"SLC6A7","Gene synonym":["PROT"],"Ensembl":"ENSG00000011083","Gene description":"Solute carrier family 6 member 7","Uniprot":["Q99884"],"Chromosome":"5","Position":"150190062-150222788","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"37","RNA tissue specific nTPM":{"brain":"21.5","intestine":"5.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"41.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"2.1"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028907","HPA063773"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028907":"AB_10602404","HPA063773":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"}},{"Gene":"SLC6A8","Gene synonym":["CRTR","CT1"],"Ensembl":"ENSG00000130821","Gene description":"Solute carrier family 6 member 8","Uniprot":["P48029"],"Chromosome":"X","Position":"153687926-153696588","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Sodium transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"122.8","Cone photoreceptor cells":"127.5","Distal enterocytes":"139.7","Ionocytes":"120.0","Proximal enterocytes":"199.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Lung - Smooth muscle cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.53e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.39e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"}},{"Gene":"SLC6A9","Gene synonym":["GLYT1"],"Ensembl":"ENSG00000196517","Gene description":"Solute carrier family 6 member 9","Uniprot":["P48067"],"Chromosome":"1","Position":"43991500-44031467","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Neurotransmitter transport","Symport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"72.4","skin 1":"46.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"27.4","Erythroid cells":"35.0","Horizontal cells":"44.9","Suprabasal keratinocytes":"19.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"18.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013977"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA013977":"AB_1849835"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.50e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"}},{"Gene":"SLC7A1","Gene synonym":["ATRC1","CAT-1","ERR","HCAT1","REC1L"],"Ensembl":"ENSG00000139514","Gene description":"Solute carrier family 7 member 1","Uniprot":["P30825"],"Chromosome":"13","Position":"29509414-29595688","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"55.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"229.6","Microglial cells":"157.8","Squamous epithelial cells":"156.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039721","HPA077838"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039721":"AB_10672893","HPA077838":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-3"}},{"Gene":"SLC7A10","Gene synonym":["asc-1"],"Ensembl":"ENSG00000130876","Gene description":"Solute carrier family 7 member 10","Uniprot":["Q9NS82"],"Chromosome":"19","Position":"33208664-33225850","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"adipose tissue":"31.8","brain":"12.7","breast":"12.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"39.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"1.6","Gastric cancer":"1.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skin - Adipocytes (Skin)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041884","HPA057036"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA041884":"AB_10794494","HPA057036":"AB_2683317"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"}},{"Gene":"SLC7A11","Gene synonym":["xCT"],"Ensembl":"ENSG00000151012","Gene description":"Solute carrier family 7 member 11","Uniprot":["Q9UPY5"],"Chromosome":"4","Position":"138164097-138242349","Protein class":["FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"26.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"357.1","dendritic cells":"76.2","Gastric mucus-secreting cells":"58.4","Langerhans cells":"70.1","Microglial cells":"145.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Gallbladder cancer":"153.9"},"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064215"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA064215":"AB_2685213"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.77e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"SLC7A13","Gene synonym":["AGT-1","XAT2"],"Ensembl":"ENSG00000164893","Gene description":"Solute carrier family 7 member 13","Uniprot":["Q8TCU3"],"Chromosome":"8","Position":"86214063-86321146","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"234","RNA tissue specific nTPM":{"kidney":"42.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Proximal tubular cells":"21.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-5"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLC7A14","Gene synonym":["KIAA1613","PPP1R142"],"Ensembl":"ENSG00000013293","Gene description":"Solute carrier family 7 member 14","Uniprot":["Q8TBB6"],"Chromosome":"3","Position":"170459548-170586075","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"15.9","pituitary gland":"7.3","retina":"6.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"24.4","Excitatory neurons":"61.0","Horizontal cells":"30.1","Inhibitory neurons":"88.2","Oligodendrocytes":"63.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"0.8","pancreatic cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"10.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045929"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA045929":"AB_2679501"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"}},{"Gene":"SLC7A2","Gene synonym":["ATRC2","CAT-2","HCAT2"],"Ensembl":"ENSG00000003989","Gene description":"Solute carrier family 7 member 2","Uniprot":["P52569"],"Chromosome":"8","Position":"17497088-17570573","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"176.7","parathyroid gland":"224.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"159.6","Hepatocytes":"204.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009277"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA009277":"AB_2668229"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.65e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.08e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"SLC7A3","Gene synonym":["ATRC3","CAT-3","FLJ14541"],"Ensembl":"ENSG00000165349","Gene description":"Solute carrier family 7 member 3","Uniprot":["Q8WY07"],"Chromosome":"X","Position":"70925579-70931125","Protein class":["FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"19.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"2.1","Early spermatids":"9.3","Granulosa cells":"1.5","Inhibitory neurons":"1.5","Late spermatids":"2.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"testis cancer":"43.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"18","RNA cell line specific nTPM":{"testis cancer":"154.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"}},{"Gene":"SLC7A4","Gene synonym":["CAT-4","HCAT3","VH"],"Ensembl":"ENSG00000099960","Gene description":"Solute carrier family 7 member 4","Uniprot":["O43246"],"Chromosome":"22","Position":"21028718-21032840","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"15.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"23.1","Endometrial ciliated cells":"14.5","Glandular and luminal cells":"32.5","Intestinal goblet cells":"9.9","Prostatic glandular cells":"9.7","Syncytiotrophoblasts":"11.1","Thymic epithelial cells":"17.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"3.7"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031023"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA031023":"AB_10669669"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"}},{"Gene":"SLC7A5","Gene synonym":["CD98","D16S469E","E16","LAT1","MPE16"],"Ensembl":"ENSG00000103257","Gene description":"Solute carrier family 7 member 5","Uniprot":["Q01650"],"Chromosome":"16","Position":"87830023-87869507","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"110.7","brain":"121.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"165.5","dendritic cells":"332.8","Plasma cells":"120.0","Syncytiotrophoblasts":"134.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"plasmacytoid DC":"17.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"17.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052673","HPA056077"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"51000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA052673":"AB_2681909","HPA056077":"AB_2683031"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.43e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-3"}},{"Gene":"SLC7A6","Gene synonym":["KIAA0245","LAT-2","LAT3","y+LAT-2"],"Ensembl":"ENSG00000103064","Gene description":"Solute carrier family 7 member 6","Uniprot":["Q92536"],"Chromosome":"16","Position":"68264516-68301823","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Antiport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"75.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"53.8","Skeletal myocytes":"96.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050713"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA050713":"AB_2681218"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.84e-4"}},{"Gene":"SLC7A7","Gene synonym":["LPI","y+LAT-1"],"Ensembl":"ENSG00000155465","Gene description":"Solute carrier family 7 member 7","Uniprot":["Q9UM01"],"Chromosome":"14","Position":"22773222-22829820","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"131.6","kidney":"300.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"250.9","Kupffer cells":"227.4","Macrophages":"158.7","monocytes":"228.8","Proximal enterocytes":"406.0","Proximal tubular cells":"266.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"299.9","intermediate monocyte":"410.0","non-classical monocyte":"457.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"457.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Lung - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036227"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036227":"AB_10696653"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.28e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"}},{"Gene":"SLC7A8","Gene synonym":["LAT2","LPI-PC1"],"Ensembl":"ENSG00000092068","Gene description":"Solute carrier family 7 member 8","Uniprot":["Q9UHI5"],"Chromosome":"14","Position":"23125295-23183674","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"331.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"99.1","Endometrial stromal cells":"73.6","Proximal tubular cells":"88.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"9.3","eosinophil":"14.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"14.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB046015","HPA051950","HPA060672"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB046015":"AB_2239464","HPA051950":"AB_2681670","HPA060672":"AB_2684340"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.97e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.15e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-4"}},{"Gene":"SLC7A9","Gene synonym":["CSNU3"],"Ensembl":"ENSG00000021488","Gene description":"Solute carrier family 7 member 9","Uniprot":["P82251"],"Chromosome":"19","Position":"32830509-32869767","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":null,"Disease involvement":["Cystinuria","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"124.6","kidney":"68.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Proximal enterocytes":"830.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"liver cancer":"6.6","renal cancer":"5.2","stomach cancer":"1.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"3.4"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042591"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042591":"AB_10962500"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-5"}},{"Gene":"SLC8A1","Gene synonym":["NCX1"],"Ensembl":"ENSG00000183023","Gene description":"Solute carrier family 8 member A1","Uniprot":["P32418"],"Chromosome":"2","Position":"40097270-40611053","Protein class":["FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Sodium transport","Transport"],"Molecular function":["Calmodulin-binding"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"117.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Cardiomyocytes":"954.7","Excitatory neurons":"1248.3","Inhibitory neurons":"614.0","Microglial cells":"559.1","Oligodendrocyte precursor cells":"721.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"44.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"44.2","monocytes":"11.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Smooth muscle cells","Kidney - Intercalated cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022694","HPA070007"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB022694":null,"HPA070007":"AB_2686227"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"}},{"Gene":"SLC8A2","Gene synonym":["KIAA1087","NCX2"],"Ensembl":"ENSG00000118160","Gene description":"Solute carrier family 8 member A2","Uniprot":["Q9UPR5"],"Chromosome":"19","Position":"47428017-47471893","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Sodium transport","Transport"],"Molecular function":["Calmodulin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"38.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"11.0","Excitatory neurons":"39.7","Horizontal cells":"7.7","Inhibitory neurons":"13.2","Oligodendrocytes":"6.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"3.4","thyroid cancer":"4.0"},"RNA tissue cell type enrichment":["Colon - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050818","HPA054671"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050818":"AB_2681248","HPA054671":"AB_2682568"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"}},{"Gene":"SLC8A3","Gene synonym":["NCX3"],"Ensembl":"ENSG00000100678","Gene description":"Solute carrier family 8 member A3","Uniprot":["P57103"],"Chromosome":"14","Position":"70044215-70189070","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Sodium transport","Transport"],"Molecular function":["Calmodulin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"10.8","retina":"9.6","skeletal muscle":"20.6","tongue":"9.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"79.3","Inhibitory neurons":"126.4","Oligodendrocyte precursor cells":"102.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"7.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Adipose visceral - Mast cells","Colon - Mast cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"}},{"Gene":"SLC8B1","Gene synonym":["FLJ22233","NCKX6","NCLX","SLC24A6"],"Ensembl":"ENSG00000089060","Gene description":"Solute carrier family 8 member B1","Uniprot":["Q6J4K2"],"Chromosome":"12","Position":"113298759-113359493","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Ion transport","Sensory transduction","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"75.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Theca cells":"74.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040668"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040668":"AB_10793861"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.52e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.02e-4"}},{"Gene":"SLC9A1","Gene synonym":["APNH","NHE1","PPP1R143"],"Ensembl":"ENSG00000090020","Gene description":"Solute carrier family 9 member A1","Uniprot":["P19634"],"Chromosome":"1","Position":"27098809-27166981","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":["Calmodulin-binding"],"Disease involvement":["Deafness","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"76.5","stomach 1":"65.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"186.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022371","HPA048532","HPA052891"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"21000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB022371":null,"HPA048532":"AB_2680431","HPA052891":"AB_2681981"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.47e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.10e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"}},{"Gene":"SLC9A2","Gene synonym":["NHE2"],"Ensembl":"ENSG00000115616","Gene description":"Solute carrier family 9 member A2","Uniprot":["Q9UBY0"],"Chromosome":"2","Position":"102619553-102711355","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"20.7","stomach 1":"26.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"43.6","Early spermatids":"54.9","Enteroendocrine cells":"22.1","Gastric mucus-secreting cells":"47.1","Intestinal goblet cells":"28.9","Late spermatids":"27.8","Paneth cells":"30.8","Prostatic glandular cells":"23.3","Undifferentiated cells":"21.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Prostate - Prostate glandular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035121","HPA035122"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA035121":"AB_10602894","HPA035122":"AB_2674477"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"}},{"Gene":"SLC9A3","Gene synonym":["NHE3"],"Ensembl":"ENSG00000066230","Gene description":"Solute carrier family 9 member A3","Uniprot":["P48764"],"Chromosome":"5","Position":"470456-524449","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"45.4","intestine":"94.3","kidney":"62.5","stomach 1":"50.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"8.7","Squamous epithelial cells":"7.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"14.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"14","RNA mouse brain regional specific nTPM":{"cerebellum":"4.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036493","HPA036669"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA036493":"AB_10673353","HPA036669":"AB_10670843"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.49e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"SLC9A4","Gene synonym":["NHE4"],"Ensembl":"ENSG00000180251","Gene description":"Solute carrier family 9 member A4","Uniprot":["Q6AI14"],"Chromosome":"2","Position":"102473226-102533972","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"stomach 1":"53.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"59.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"2.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"2.7"},"RNA tissue cell type enrichment":["Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"18","RNA mouse brain regional specific nTPM":{"hippocampal formation":"10.6","olfactory bulb":"6.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036096"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA036096":"AB_2674939"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"}},{"Gene":"SLC9A5","Gene synonym":["NHE5"],"Ensembl":"ENSG00000135740","Gene description":"Solute carrier family 9 member A5","Uniprot":["Q14940"],"Chromosome":"16","Position":"67237683-67272191","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.6","lymphoid tissue":"17.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"10.9","Horizontal cells":"16.7","Inhibitory neurons":"12.0","Oligodendrocyte precursor cells":"6.7","Spermatocytes":"16.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041004","HPA041329"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA041004":"AB_10794433","HPA041329":"AB_10794373"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"}},{"Gene":"SLC9A6","Gene synonym":["KIAA0267","NHE6"],"Ensembl":"ENSG00000198689","Gene description":"Solute carrier family 9 member A6","Uniprot":["Q92581"],"Chromosome":"X","Position":"135973841-136047269","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059445","HPA059590"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059445":"AB_2684021","HPA059590":"AB_2684075"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"}},{"Gene":"SLC9A7","Gene synonym":["NHE7"],"Ensembl":"ENSG00000065923","Gene description":"Solute carrier family 9 member A7","Uniprot":["Q96T83"],"Chromosome":"X","Position":"46599251-46759118","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Potassium transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"41.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"53.8","Excitatory neurons":"42.8","Inhibitory neurons":"65.3","Oligodendrocyte precursor cells":"66.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"2.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048938","HPA075385"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA048938":"AB_2680565","HPA075385":"AB_2686747"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.58e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.14e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"}},{"Gene":"SLC9A8","Gene synonym":["KIAA0939","NHE8"],"Ensembl":"ENSG00000197818","Gene description":"Solute carrier family 9 member A8","Uniprot":["Q9Y2E8"],"Chromosome":"20","Position":"49812713-49892242","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033682"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033682":"AB_2270441"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"}},{"Gene":"SLC9A9","Gene synonym":["FLJ35613","NHE9"],"Ensembl":"ENSG00000181804","Gene description":"Solute carrier family 9 member A9","Uniprot":["Q8IVB4"],"Chromosome":"3","Position":"143265222-143848485","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":["Autism","Autism spectrum disorder"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"145.2","Inhibitory neurons":"156.9","Microglial cells":"385.8","Oligodendrocyte precursor cells":"261.4","Oligodendrocytes":"407.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"9.6"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058234"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058234":"AB_2683648"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.18e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.57e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"}},{"Gene":"SLC9B1","Gene synonym":["NHA1","NHEDC1"],"Ensembl":"ENSG00000164037","Gene description":"Solute carrier family 9 member B1","Uniprot":["Q4ZJI4"],"Chromosome":"4","Position":"102885048-103019719","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Fertilization","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"testis":"40.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"190.1","Late spermatids":"99.0","Spermatocytes":"172.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058971","HPA065520"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centriolar satellite","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA058971":"AB_2683865","HPA065520":"AB_2685502"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"}},{"Gene":"SLC9B2","Gene synonym":["FLJ23984","NHA2","NHEDC2"],"Ensembl":"ENSG00000164038","Gene description":"Solute carrier family 9 member B2","Uniprot":["Q86UD5"],"Chromosome":"4","Position":"103019868-103085829","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Hydrogen ion transport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"38.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"57.1","Hepatocytes":"37.7","Inhibitory neurons":"55.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"11.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"5.1","NK-cells":"11.8","T-cells":"6.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047008"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA047008":"AB_2679901"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-5"}},{"Gene":"SLC9C1","Gene synonym":["NHE","SLC9A10"],"Ensembl":"ENSG00000172139","Gene description":"Solute carrier family 9 member C1","Uniprot":["Q4G0N8"],"Chromosome":"3","Position":"112140898-112294227","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Differentiation","Ion transport","Sodium transport","Spermatogenesis","Transport"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"skin 1":"2.1","testis":"8.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"3.3","Early spermatids":"4.0","Excitatory neurons":"4.2","Inhibitory neurons":"2.7","Microglial cells":"2.7","Oligodendrocyte precursor cells":"4.8","Oligodendrocytes":"4.8","Spermatocytes":"11.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"}},{"Gene":"SLC9C2","Gene synonym":["MGC43026","SLC9A11"],"Ensembl":"ENSG00000162753","Gene description":"Solute carrier family 9 member C2 (putative)","Uniprot":["Q5TAH2"],"Chromosome":"1","Position":"173500460-173603072","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Sodium transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.3","choroid plexus":"1.9","testis":"6.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"26.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059122","HPA079529"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA059122":null,"HPA079529":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"}},{"Gene":"SLCO1A2","Gene synonym":["OATP","OATP-A","OATP1A2","SLC21A3"],"Ensembl":"ENSG00000084453","Gene description":"Solute carrier organic anion transporter family member 1A2","Uniprot":["P46721"],"Chromosome":"12","Position":"21264600-21419594","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"82.0","choroid plexus":"28.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"460.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"16.1"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071152"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA071152":"AB_2686350"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"}},{"Gene":"SLCO1B1","Gene synonym":["LST-1","OATP-C","OATP1B1","SLC21A6"],"Ensembl":"ENSG00000134538","Gene description":"Solute carrier organic anion transporter family member 1B1","Uniprot":["Q9Y6L6"],"Chromosome":"12","Position":"21131194-21239796","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"614","RNA tissue specific nTPM":{"liver":"537.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Hepatocytes":"157.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"96","RNA cancer specific FPKM":{"liver cancer":"52.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"2.2"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050892","HPA073093"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA050892":"AB_2681265","HPA073093":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"}},{"Gene":"SLCO1B3","Gene synonym":["OATP1B3","OATP8","SLC21A8"],"Ensembl":"ENSG00000111700","Gene description":"Solute carrier organic anion transporter family member 1B3","Uniprot":["Q9NPD5"],"Chromosome":"12","Position":"20810702-20916911","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"liver":"265.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"25","RNA single cell type specific nTPM":{"Hepatocytes":"200.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"5.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"51.9"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004943","HPA050892"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA004943":"AB_1854758","HPA050892":"AB_2681265"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-3"}},{"Gene":"SLCO1B3-SLCO1B7","Gene synonym":["LST-3TM12","OATP1B3-1B7"],"Ensembl":"ENSG00000257046","Gene description":"SLCO1B3-SLCO1B7 readthrough","Uniprot":[],"Chromosome":"12","Position":"20815674-21090245","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"breast":"21.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"3.5"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050892"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 5: Breast - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050892":"AB_2681265"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLCO1C1","Gene synonym":["OATP-F","OATP1","OATP1C1","SLC21A14"],"Ensembl":"ENSG00000139155","Gene description":"Solute carrier organic anion transporter family member 1C1","Uniprot":["Q9NYB5"],"Chromosome":"12","Position":"20695332-20753386","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"22.2","choroid plexus":"28.3","pituitary gland":"8.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Astrocytes":"283.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"glioma":"4.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"cervical cancer":"1.2"},"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"}},{"Gene":"SLCO2A1","Gene synonym":["MATR1","OATP2A1","PGT","SLC21A2"],"Ensembl":"ENSG00000174640","Gene description":"Solute carrier organic anion transporter family member 2A1","Uniprot":["Q92959"],"Chromosome":"3","Position":"133932701-134052184","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"123.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"109.3","Endothelial cells":"122.5","Exocrine glandular cells":"29.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"13.7"},"RNA tissue cell type enrichment":["Colon - Endothelial cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013742"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013742":"AB_2668877"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.69e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.24e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.25e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"}},{"Gene":"SLCO2B1","Gene synonym":["OATP-B","OATP2B1","SLC21A9"],"Ensembl":"ENSG00000137491","Gene description":"Solute carrier organic anion transporter family member 2B1","Uniprot":["O94956"],"Chromosome":"11","Position":"75100563-75206549","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"229.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"188.4","Hofbauer cells":"108.1","Kupffer cells":"79.1","Macrophages":"128.7","Microglial cells":"226.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"20.9","liver cancer":"20.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Kidney - Macrophages","Liver - Hepatocytes","Lung - Macrophages","Skeletal muscle - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020659"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA020659":"AB_1857219"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"}},{"Gene":"SLCO3A1","Gene synonym":["OATP-D","OATP3A1","SLC21A11"],"Ensembl":"ENSG00000176463","Gene description":"Solute carrier organic anion transporter family member 3A1","Uniprot":["Q9UIG8"],"Chromosome":"15","Position":"91853708-92172435","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"39.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"590.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066327"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066327":"AB_2732743"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.61e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.57e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"}},{"Gene":"SLCO4A1","Gene synonym":["OATP-E","OATP4A1","SLC21A12"],"Ensembl":"ENSG00000101187","Gene description":"Solute carrier organic anion transporter family member 4A1","Uniprot":["Q96BD0"],"Chromosome":"20","Position":"62642503-62685785","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"57.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"61.8","Endothelial cells":"56.7","Extravillous trophoblasts":"271.2","Melanocytes":"73.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"21.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebellum":"6.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030669","HPA030670"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA030669":"AB_10601163","HPA030670":"AB_10670033"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.74e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"SLCO4C1","Gene synonym":["OATP-H","OATP4C1","OATPX","SLC21A20"],"Ensembl":"ENSG00000173930","Gene description":"Solute carrier organic anion transporter family member 4C1","Uniprot":["Q6ZQN7"],"Chromosome":"5","Position":"102233986-102296284","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Ion transport","Spermatogenesis","Transport"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"kidney":"41.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"42.2","Early spermatids":"25.4","NK-cells":"17.6","Proximal tubular cells":"25.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"renal cancer":"22.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"9.5","neutrophil":"9.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"9.8","NK-cells":"2.6","T-cells":"3.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"7.2"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Alveolar cells type 2","Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058249"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA058249":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"}},{"Gene":"SLCO5A1","Gene synonym":["OATP-J","OATP5A1","OATPRP4","SLC21A15"],"Ensembl":"ENSG00000137571","Gene description":"Solute carrier organic anion transporter family member 5A1","Uniprot":["Q9H2Y9"],"Chromosome":"8","Position":"69667046-69834978","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"6.5","skeletal muscle":"7.6","tongue":"11.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"21.1","Inhibitory neurons":"29.4","Oligodendrocyte precursor cells":"25.0","Plasma cells":"12.7","Prostatic glandular cells":"20.9","Skeletal myocytes":"24.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"1.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"20.3"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"basal ganglia":"2.3","olfactory bulb":"6.7"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"olfactory bulb":"12.8"},"Antibody":["HPA025062"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA025062":"AB_1857220"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"}},{"Gene":"SLCO6A1","Gene synonym":["CT48","MGC26949","OATP6A1","OATPY"],"Ensembl":"ENSG00000205359","Gene description":"Solute carrier organic anion transporter family member 6A1","Uniprot":["Q86UG4"],"Chromosome":"5","Position":"102371774-102499016","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"109","RNA tissue specific nTPM":{"testis":"30.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"209.8","Spermatocytes":"104.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054126"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054126":"AB_2682390"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"}},{"Gene":"SLF1","Gene synonym":["ANKRD32","BRCTD1","BRCTx","DKFZp564C0469","DKFZp761C121"],"Ensembl":"ENSG00000133302","Gene description":"SMC5-SMC6 complex localization factor 1","Uniprot":["Q9BQI6"],"Chromosome":"5","Position":"94618669-94739436","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"93.1","Spermatocytes":"148.1","Spermatogonia":"101.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040793","HPA054213"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA040793":"AB_10796560","HPA054213":"AB_2682419"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"}},{"Gene":"SLF2","Gene synonym":["C10orf6","FAM178A","FLJ10512","FLJ25012"],"Ensembl":"ENSG00000119906","Gene description":"SMC5-SMC6 complex localization factor 2","Uniprot":["Q8IX21"],"Chromosome":"10","Position":"100912963-100965134","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"109.4","Oligodendrocytes":"190.6","Peritubular cells":"104.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038499","HPA057568"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA038499":"AB_10672520","HPA057568":"AB_2683471"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"}},{"Gene":"SLFN12L","Gene synonym":[],"Ensembl":"ENSG00000205045","Gene description":"Schlafen family member 12 like","Uniprot":["Q6IEE8"],"Chromosome":"17","Position":"35464249-35487857","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"3.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"NK-cells":"36.7","T-cells":"14.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"3.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"1.0","NK-cells":"3.6","T-cells":"1.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Prostate - T-cells","Stomach - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024447"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024447":"AB_1856614"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-3"}},{"Gene":"SLIT2","Gene synonym":["SLIL3","Slit-2"],"Ensembl":"ENSG00000145147","Gene description":"Slit guidance ligand 2","Uniprot":["O94813"],"Chromosome":"4","Position":"20251905-20620561","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Chemotaxis","Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Heparin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"253.9","Inhibitory neurons":"534.8","Oligodendrocytes":"149.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"25.4"},"RNA tissue cell type enrichment":["Breast - Fibroblasts","Heart muscle - Fibroblasts","Liver - Hepatic stellate cells","Lung - Fibroblast_1","Pancreas - Fibroblasts","Prostate - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB007590","HPA019511","HPA023088"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"77000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB007590":null,"HPA019511":"AB_1857226","HPA023088":"AB_1857227"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.51e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-4"}},{"Gene":"SLITRK1","Gene synonym":["KIAA1910","LRRC12"],"Ensembl":"ENSG00000178235","Gene description":"SLIT and NTRK like family member 1","Uniprot":["Q96PX8"],"Chromosome":"13","Position":"83877205-83882474","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"13.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"20.4","Excitatory neurons":"18.1","Inhibitory neurons":"13.6","Oligodendrocyte precursor cells":"24.1","Oligodendrocytes":"13.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"1.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"4.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074835"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"330000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074835":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SLITRK2","Gene synonym":["CXorf1","CXorf2","KIAA1854","SLITL1","TMEM257"],"Ensembl":"ENSG00000185985","Gene description":"SLIT and NTRK like family member 2","Uniprot":["Q9H156"],"Chromosome":"X","Position":"145817829-145829856","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"12.5","retina":"32.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"32.3","Melanocytes":"50.5","Muller glia cells":"185.0","Oligodendrocyte precursor cells":"46.7","Oligodendrocytes":"24.2","Schwann cells":"23.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"1.3","skin cancer":"1.5"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"}},{"Gene":"SLITRK3","Gene synonym":["KIAA0848"],"Ensembl":"ENSG00000121871","Gene description":"SLIT and NTRK like family member 3","Uniprot":["O94933"],"Chromosome":"3","Position":"165186720-165197109","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"9.0","fallopian tube":"9.6","liver":"7.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Bipolar cells":"6.1","Excitatory neurons":"10.8","Inhibitory neurons":"15.5","Oligodendrocyte precursor cells":"20.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"22","RNA cancer specific FPKM":{"glioma":"7.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bone cancer":"11.4"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017636","HPA048042"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2600000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA017636":"AB_1857232","HPA048042":"AB_2732542"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-4"}},{"Gene":"SLITRK4","Gene synonym":["DKFZp547M2010"],"Ensembl":"ENSG00000179542","Gene description":"SLIT and NTRK like family member 4","Uniprot":["Q8IW52"],"Chromosome":"X","Position":"143622790-143636101","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"11.1","brain":"9.0","skeletal muscle":"8.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"51.6","Granulosa cells":"34.7","Inhibitory neurons":"47.5","Leydig cells":"48.9","Oligodendrocyte precursor cells":"28.4","Skeletal myocytes":"20.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"renal cancer":"3.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"11.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"64","RNA blood lineage specific nTPM":{"dendritic cells":"3.2","granulocytes":"11.6","monocytes":"4.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000431"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"420000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000431":"AB_2665991"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-3"}},{"Gene":"SLITRK5","Gene synonym":["bA364G4.2","KIAA0918","LRRC11"],"Ensembl":"ENSG00000165300","Gene description":"SLIT and NTRK like family member 5","Uniprot":["O94991"],"Chromosome":"13","Position":"87672615-87696272","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.6","fallopian tube":"2.9","salivary gland":"3.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"32.8","Excitatory neurons":"20.1","Horizontal cells":"13.5","Inhibitory neurons":"13.0","Oligodendrocyte precursor cells":"10.6","Schwann cells":"19.4","Serous glandular cells":"22.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013843","HPA073230"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA013843":"AB_1857233","HPA073230":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"}},{"Gene":"SLITRK6","Gene synonym":["FLJ22774"],"Ensembl":"ENSG00000184564","Gene description":"SLIT and NTRK like family member 6","Uniprot":["Q9H5Y7"],"Chromosome":"13","Position":"85792790-85806683","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Hearing","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"27.7","urinary bladder":"14.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"22.5","Bipolar cells":"39.2","Club cells":"33.3","Ionocytes":"31.0","Mucus glandular cells":"49.3","Respiratory ciliated cells":"18.1","Salivary duct cells":"41.5","Schwann cells":"21.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"21.1","urothelial cancer":"18.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"41.3"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"thalamus":"22.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014491","HPA014513"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014491":"AB_10601603","HPA014513":"AB_2669026"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.52e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"}},{"Gene":"SLK","Gene synonym":["KIAA0204","se20-9","STK2"],"Ensembl":"ENSG00000065613","Gene description":"STE20 like kinase","Uniprot":["Q9H2G2"],"Chromosome":"10","Position":"103967140-104029233","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015757","HPA056556"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015757":"AB_1857236","HPA056556":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.77e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.95e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"SLMAP","Gene synonym":["KIAA1601","SLAP"],"Ensembl":"ENSG00000163681","Gene description":"Sarcolemma associated protein","Uniprot":["Q14BN4"],"Chromosome":"3","Position":"57755450-57930003","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"482.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Smooth muscle cells","Prostate - Smooth muscle cells","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002357","HPA002358"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9200","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA002357":"AB_1080023","HPA002358":"AB_1080021"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.98e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"}},{"Gene":"SLN","Gene synonym":["MGC12301","MGC125854","MGC125855"],"Ensembl":"ENSG00000170290","Gene description":"Sarcolipin","Uniprot":["O00631"],"Chromosome":"11","Position":"107707378-107719693","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skeletal muscle":"8190.2","tongue":"3399.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"919.6","Skeletal myocytes":"2590.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"21.6","head and neck cancer":"22.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"32","RNA cell line specific nTPM":{"Rhabdoid":"194.9"},"RNA tissue cell type enrichment":["Skin - Inner root sheath cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011628"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB011628":"AB_2195046"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-8"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.52e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"}},{"Gene":"SMAD2","Gene synonym":["JV18-1","MADH2","MADR2"],"Ensembl":"ENSG00000175387","Gene description":"SMAD family member 2","Uniprot":["Q15796"],"Chromosome":"18","Position":"47808957-47931146","Protein class":["Cancer-related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025507","HPA067203","CAB073546"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB025507":null,"CAB073546":null,"HPA067203":"AB_2685803"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.44e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"}},{"Gene":"SMAD3","Gene synonym":["HsT17436","JV15-2","MADH3"],"Ensembl":"ENSG00000166949","Gene description":"SMAD family member 3","Uniprot":["P84022"],"Chromosome":"15","Position":"67063763-67195173","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Aortic aneurysm","Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"159.8","Oligodendrocyte precursor cells":"134.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008094","HPA046386","HPA067203","CAB069409"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB008094":"AB_2302271","CAB069409":"AB_1622941","HPA046386":"AB_2679647","HPA067203":"AB_2685803"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"}},{"Gene":"SMAD4","Gene synonym":["DPC4","MADH4"],"Ensembl":"ENSG00000141646","Gene description":"SMAD family member 4","Uniprot":["Q13485"],"Chromosome":"18","Position":"51028394-51085045","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"130.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019154","CAB080136"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"CAB080136":null,"HPA019154":"AB_1853480"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.92e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"SMAD5","Gene synonym":["Dwfc","JV5-1","MADH5"],"Ensembl":"ENSG00000113658","Gene description":"SMAD family member 5","Uniprot":["Q99717"],"Chromosome":"5","Position":"136132845-136188747","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"91.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"91.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058931"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA058931":"AB_2683856"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"}},{"Gene":"SMAGP","Gene synonym":["hSMAGP","MGC149453","MGC149454"],"Ensembl":"ENSG00000170545","Gene description":"Small cell adhesion glycoprotein","Uniprot":["Q0VAQ4"],"Chromosome":"12","Position":"51244558-51270415","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"139.8","placenta":"102.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Cytotrophoblasts":"1258.7","Syncytiotrophoblasts":"755.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Heart muscle - Endothelial cells","Skeletal muscle - Endothelial cells","Stomach - Gastric mucous cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039711"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cell Junctions"],"Antibody RRID":{"HPA039711":"AB_10674985"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.36e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.38e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"}},{"Gene":"SMARCAL1","Gene synonym":["HARP","HHARP"],"Ensembl":"ENSG00000138375","Gene description":"SWI\/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1","Uniprot":["Q9NZC9"],"Chromosome":"2","Position":"216412414-216483053","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"33.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020337"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA020337":"AB_2670410"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.22e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"}},{"Gene":"SMARCB1","Gene synonym":["BAF47","hSNFS","Ini1","PPP1R144","RDT","Sfh1p","SNF5","SNF5L1","Snr1"],"Ensembl":"ENSG00000099956","Gene description":"SWI\/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1","Uniprot":["Q12824"],"Chromosome":"22","Position":"23786931-23838009","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Host-virus interaction","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Hypotrichosis","Intellectual disability","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"253.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"21.4"},"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009196","HPA018248","HPA019127"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"CAB009196":"AB_2191983","HPA018248":"AB_1851162","HPA019127":"AB_1851165"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.52e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"}},{"Gene":"SMC6","Gene synonym":["FLJ22116","SMC6L1"],"Ensembl":"ENSG00000163029","Gene description":"Structural maintenance of chromosomes 6","Uniprot":["Q96SB8"],"Chromosome":"2","Position":"17663812-17800242","Protein class":["Predicted intracellular proteins"],"Biological process":["DNA damage","DNA recombination","DNA repair"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"181.3","Spermatocytes":"142.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035057","CAB037186","HPA042733"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB037186":"AB_1080031","HPA035057":"AB_2674435","HPA042733":"AB_2678134"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.15e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"}},{"Gene":"SMCO2","Gene synonym":["C12orf70","LOC341346"],"Ensembl":"ENSG00000165935","Gene description":"Single-pass membrane protein with coiled-coil domains 2","Uniprot":["A6NFE2"],"Chromosome":"12","Position":"27466810-27502185","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"16.9","Excitatory neurons":"9.3","Inhibitory neurons":"3.6","Late spermatids":"5.5","Pancreatic endocrine cells":"3.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014366"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014366":"AB_1845544"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"}},{"Gene":"SMCO3","Gene synonym":["C12orf69","LOC440087"],"Ensembl":"ENSG00000179256","Gene description":"Single-pass membrane protein with coiled-coil domains 3","Uniprot":["A2RU48"],"Chromosome":"12","Position":"14804650-14814182","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"3.4","kidney":"3.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"1.9","Collecting duct cells":"2.0","Distal tubular cells":"9.3","Prostatic glandular cells":"1.9","Proximal tubular cells":"6.1","Schwann cells":"4.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"3.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"1.4"},"RNA tissue cell type enrichment":["Kidney - Podocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"spinal cord":"3.6"},"Antibody":["HPA040574","HPA047804"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA040574":"AB_2677026","HPA047804":"AB_2680160"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"}},{"Gene":"SMCO4","Gene synonym":["C11orf75","FN5"],"Ensembl":"ENSG00000166002","Gene description":"Single-pass membrane protein with coiled-coil domains 4","Uniprot":["Q9NRQ5"],"Chromosome":"11","Position":"93478472-93543391","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"195.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"205.2","Hofbauer cells":"177.8","Proximal enterocytes":"192.4","Serous glandular cells":"197.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Macrophages","Prostate - Prostate glandular cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041120"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041120":"AB_2677309"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.81e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"}},{"Gene":"SMDT1","Gene synonym":["C22orf32","DDDD","dJ186O1.1","EMRE"],"Ensembl":"ENSG00000183172","Gene description":"Single-pass membrane protein with aspartate rich tail 1","Uniprot":["Q9H4I9"],"Chromosome":"22","Position":"42079691-42084284","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032117","HPA060340"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA032117":"AB_10601093","HPA060340":"AB_2684257"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.32e-8"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.87e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.36e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"}},{"Gene":"SMG1","Gene synonym":["ATX","KIAA0421","LIP"],"Ensembl":"ENSG00000157106","Gene description":"SMG1 nonsense mediated mRNA decay associated PI3K related kinase","Uniprot":["Q96Q15"],"Chromosome":"16","Position":"18804860-18926408","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Nonsense-mediated mRNA decay"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"276.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"31.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"31.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006870","HPA031623","HPA073972"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA006870":"AB_1079725","HPA031623":"AB_2673962","HPA073972":"AB_2686648"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"}},{"Gene":"SMG5","Gene synonym":["EST1B","KIAA1089","LPTS-RP1","LPTSRP1","RP11-54H19.7","SMG-5"],"Ensembl":"ENSG00000198952","Gene description":"SMG5 nonsense mediated mRNA decay factor","Uniprot":["Q9UPR3"],"Chromosome":"1","Position":"156249224-156282825","Protein class":["Predicted membrane proteins"],"Biological process":["Nonsense-mediated mRNA decay"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072651"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytoplasmic bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA072651":"AB_2686544"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.39e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.70e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"}},{"Gene":"SMG6","Gene synonym":["C17orf31","EST1A","KIAA0732","SMG-6"],"Ensembl":"ENSG00000070366","Gene description":"SMG6 nonsense mediated mRNA decay factor","Uniprot":["Q86US8"],"Chromosome":"17","Position":"2059839-2303785","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Nonsense-mediated mRNA decay"],"Molecular function":["DNA-binding","Endonuclease","Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042932"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA042932":"AB_10964261"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.30e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"}},{"Gene":"SMG7","Gene synonym":["C1orf16","EST1C","KIAA0250","SGA56M","SMG-7"],"Ensembl":"ENSG00000116698","Gene description":"SMG7 nonsense mediated mRNA decay factor","Uniprot":["Q92540"],"Chromosome":"1","Position":"183472216-183598246","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Nonsense-mediated mRNA decay"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029350"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029350":"AB_10603031"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-3"}},{"Gene":"SMG8","Gene synonym":["C17orf71","FLJ10587","FLJ23205"],"Ensembl":"ENSG00000167447","Gene description":"SMG8 nonsense mediated mRNA decay factor","Uniprot":["Q8ND04"],"Chromosome":"17","Position":"59209400-59215239","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Nonsense-mediated mRNA decay"],"Molecular function":null,"Disease involvement":["Cataract","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024841"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA024841":"AB_10600790"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.72e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"}},{"Gene":"SMG9","Gene synonym":["C19orf61","FLJ12886"],"Ensembl":"ENSG00000105771","Gene description":"SMG9 nonsense mediated mRNA decay factor","Uniprot":["Q9H0W8"],"Chromosome":"19","Position":"43727983-43754962","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Nonsense-mediated mRNA decay"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"96.9","Late spermatids":"333.7","Syncytiotrophoblasts":"99.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041763","HPA042096"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Mitochondria","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA041763":"AB_2677659","HPA042096":"AB_2677845"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.15e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.71e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.09e-4"}},{"Gene":"SMIM1","Gene synonym":["Vel"],"Ensembl":"ENSG00000235169","Gene description":"Small integral membrane protein 1 (Vel blood group)","Uniprot":["B2RUZ4"],"Chromosome":"1","Position":"3772749-3775982","Protein class":["Blood group antigen proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Blood group antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"40.3","testis":"42.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"82.3","Distal tubular cells":"87.1","Erythroid cells":"292.9","Proximal tubular cells":"225.9","Sertoli cells":"105.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"eosinophil":"48.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"granulocytes":"48.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Skin - Eccrine sweat gland cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069088"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"340000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069088":"AB_2686080"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"}},{"Gene":"SMIM10","Gene synonym":["CXorf69"],"Ensembl":"ENSG00000184785","Gene description":"Small integral membrane protein 10","Uniprot":["Q96HG1"],"Chromosome":"X","Position":"134990991-134992473","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"27.3","Erythroid cells":"45.7","Sertoli cells":"52.5","Smooth muscle cells":"40.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"2.0","NK-cell":"3.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.69e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"}},{"Gene":"SMIM11A","Gene synonym":["C21orf51","FAM165B","SMIM11"],"Ensembl":"ENSG00000205670","Gene description":"Small integral membrane protein 11A","Uniprot":["P58511"],"Chromosome":"21","Position":"34375480-34416961","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"4.8","Peritubular cells":"5.3","Sertoli cells":"5.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051321"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA051321":"AB_2681440"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-3"}},{"Gene":"SMIM11B","Gene synonym":[],"Ensembl":"ENSG00000273590","Gene description":"Small integral membrane protein 11B","Uniprot":["Q8TCY0"],"Chromosome":"21","Position":"7744962-7777853","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"6.3","Excitatory neurons":"7.7","Inhibitory neurons":"8.6","Microglial cells":"3.6","Oligodendrocyte precursor cells":"7.2","Oligodendrocytes":"11.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051321"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA051321":"AB_2681440"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMIM13","Gene synonym":["C6orf228"],"Ensembl":"ENSG00000224531","Gene description":"Small integral membrane protein 13","Uniprot":["P0DJ93"],"Chromosome":"6","Position":"11093834-11138733","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"73.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065706"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear membrane","Golgi apparatus"],"Antibody RRID":{"HPA065706":"AB_2685539"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"}},{"Gene":"SMIM14","Gene synonym":["C4orf34","FLJ13289"],"Ensembl":"ENSG00000163683","Gene description":"Small integral membrane protein 14","Uniprot":["Q96QK8"],"Chromosome":"4","Position":"39546336-39638902","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"118.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"559.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051299"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051299":"AB_2681429"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.63e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.00e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.47e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-3"}},{"Gene":"SMIM15","Gene synonym":["C5orf43","DKFZP686E2158"],"Ensembl":"ENSG00000188725","Gene description":"Small integral membrane protein 15","Uniprot":["Q7Z3B0"],"Chromosome":"5","Position":"61157704-61162468","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.23e-4"}},{"Gene":"SMIM17","Gene synonym":[],"Ensembl":"ENSG00000268182","Gene description":"Small integral membrane protein 17","Uniprot":["P0DL12"],"Chromosome":"19","Position":"56643159-56657247","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"6.4","Excitatory neurons":"17.7","Inhibitory neurons":"31.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071857","HPA071861"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA071857":"AB_2686461","HPA071861":"AB_2686462"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-3"}},{"Gene":"SMIM18","Gene synonym":[],"Ensembl":"ENSG00000253457","Gene description":"Small integral membrane protein 18","Uniprot":["P0DKX4"],"Chromosome":"8","Position":"30638580-30646064","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.4","pituitary gland":"5.4","retina":"3.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"9.4","Excitatory neurons":"2.8","Horizontal cells":"7.7","Inhibitory neurons":"5.1","Microglial cells":"4.6","Oligodendrocyte precursor cells":"5.3","Proximal tubular cells":"3.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"1.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"5.7"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066648"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA066648":"AB_2685697"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-1"}},{"Gene":"SMIM19","Gene synonym":["C8orf40"],"Ensembl":"ENSG00000176209","Gene description":"Small integral membrane protein 19","Uniprot":["Q96E16"],"Chromosome":"8","Position":"42541155-42555195","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011145","HPA074830"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA011145":"AB_1078360","HPA074830":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.74e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"}},{"Gene":"SMIM2","Gene synonym":["C13orf44","MGC5590"],"Ensembl":"ENSG00000139656","Gene description":"Small integral membrane protein 2","Uniprot":["Q9BVW6"],"Chromosome":"13","Position":"44143150-44161257","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"23.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"65.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026891","HPA077071"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA026891":"AB_10602924","HPA077071":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"}},{"Gene":"SMIM20","Gene synonym":["C4orf52","MITRAC7","PNX"],"Ensembl":"ENSG00000250317","Gene description":"Small integral membrane protein 20","Uniprot":["Q8N5G0"],"Chromosome":"4","Position":"25861830-25929874","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016552"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA016552":"AB_1859536"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.97e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"}},{"Gene":"SMIM21","Gene synonym":["C18orf62"],"Ensembl":"ENSG00000206026","Gene description":"Small integral membrane protein 21","Uniprot":["Q3B7S5"],"Chromosome":"18","Position":"75409476-75427703","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"testis":"2.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"84","RNA single cell type specific nTPM":{"Early spermatids":"74.5","Late spermatids":"53.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041686"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041686":"AB_10961179"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMIM22","Gene synonym":["CASIMO1"],"Ensembl":"ENSG00000267795","Gene description":"Small integral membrane protein 22","Uniprot":["K7EJ46"],"Chromosome":"16","Position":"4788397-4796491","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"193.6","pancreas":"154.3","salivary gland":"147.2","stomach 1":"201.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"1841.5","Enteroendocrine cells":"629.5","Intestinal goblet cells":"1127.9","Paneth cells":"1014.6","Proximal enterocytes":"1744.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"147.0","colorectal cancer":"153.8"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Colon enterocytes","Skin - Eccrine sweat gland cells","Stomach - Gastric mucous cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077331"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA077331":"AB_2686834"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"}},{"Gene":"SMIM23","Gene synonym":["C5orf50","LOC644994"],"Ensembl":"ENSG00000185662","Gene description":"Small integral membrane protein 23","Uniprot":["A6NLE4"],"Chromosome":"5","Position":"171782432-171796126","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"195","RNA tissue specific nTPM":{"testis":"25.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"80","RNA single cell type specific nTPM":{"Early spermatids":"348.2","Late spermatids":"96.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-4"}},{"Gene":"SMIM24","Gene synonym":["C19orf77","HSPC323"],"Ensembl":"ENSG00000095932","Gene description":"Small integral membrane protein 24","Uniprot":["O75264"],"Chromosome":"19","Position":"3473986-3480525","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"epididymis":"1580.8","intestine":"753.9","kidney":"844.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Proximal enterocytes":"4278.4","Proximal tubular cells":"1491.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"23.7","pancreatic cancer":"37.4","renal cancer":"78.4","stomach cancer":"52.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"5.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Gastric cancer":"34.8","Leukemia":"93.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Pancreas - Alpha cells","Prostate - Prostate glandular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045046","HPA056027"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA045046":"AB_10964444","HPA056027":"AB_2683012"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.13e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"}},{"Gene":"SMIM27","Gene synonym":["C9orf133","TOPORS-AS1"],"Ensembl":"ENSG00000235453","Gene description":"Small integral membrane protein 27","Uniprot":["A0A1B0GUW7"],"Chromosome":"9","Position":"32551144-32568621","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"186.6","Early spermatids":"452.5","Late spermatids":"200.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"680.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"680.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.18e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.11e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.39e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.33e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.46e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"}},{"Gene":"SMIM28","Gene synonym":[],"Ensembl":"ENSG00000262543","Gene description":"Small integral membrane protein 28","Uniprot":["A0A1B0GU29"],"Chromosome":"6","Position":"138377905-138383486","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"2.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Prostatic glandular cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"Neuroblastoma":"5.4","prostate cancer":"2.4"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMIM29","Gene synonym":["C6orf1","LBH","MGC57858"],"Ensembl":"ENSG00000186577","Gene description":"Small integral membrane protein 29","Uniprot":["Q86T20"],"Chromosome":"6","Position":"34246381-34249108","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"175.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"105.9","Melanocytes":"121.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"412.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037659","HPA037660"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037659":"AB_2675591","HPA037660":"AB_10671881"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.98e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"}},{"Gene":"SMIM3","Gene synonym":["C5orf62","MSTP150","NID67"],"Ensembl":"ENSG00000256235","Gene description":"Small integral membrane protein 3","Uniprot":["Q9BZL3"],"Chromosome":"5","Position":"150778757-150796734","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"161.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"201.1","granulocytes":"67.9","Muller glia cells":"67.9","Smooth muscle cells":"70.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075345"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA075345":"AB_2686744"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.15e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"}},{"Gene":"SMIM30","Gene synonym":["LINC00998"],"Ensembl":"ENSG00000214194","Gene description":"Small integral membrane protein 30","Uniprot":["A4D0T7"],"Chromosome":"7","Position":"113116718-113118560","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"273.5","Distal tubular cells":"370.1","Proximal tubular cells":"400.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"}},{"Gene":"SMIM32","Gene synonym":[],"Ensembl":"ENSG00000271824","Gene description":"Small integral membrane protein 32","Uniprot":["A0A1B0GUA5"],"Chromosome":"5","Position":"136191468-136193162","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"17.7","intestine":"12.9","kidney":"49.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Proximal tubular cells":"384.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"12.4"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"basal ganglia":"17.7","cerebral cortex":"4.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"1.9","liver cancer":"2.1","thyroid cancer":"2.5"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Pancreas - Alpha cells","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.63e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.13e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"}},{"Gene":"SMIM33","Gene synonym":[],"Ensembl":"ENSG00000283288","Gene description":"Small integral membrane protein 33","Uniprot":["A0A1B0GW64"],"Chromosome":"5","Position":"139470778-139474772","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"1.1","salivary gland":"1.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Intestinal goblet cells":"20.6"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMIM34A","Gene synonym":[],"Ensembl":"ENSG00000243627","Gene description":"Small integral membrane protein 34A","Uniprot":["A8MWV9"],"Chromosome":"21","Position":"34418715-34423951","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"fallopian tube":"1.2","kidney":"2.5"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029085"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029085":"AB_10669867"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMIM34B","Gene synonym":[],"Ensembl":"ENSG00000278961","Gene description":"Small integral membrane protein 34B","Uniprot":["P0DPE8"],"Chromosome":"21","Position":"7784482-7793954","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"4.8","kidney":"17.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"6.2","Endometrial ciliated cells":"4.0","Ionocytes":"2.2","Kupffer cells":"1.9","Late spermatids":"2.3","Respiratory ciliated cells":"12.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"lung cancer":"2.8","prostate cancer":"8.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029085"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029085":"AB_10669867"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMIM35","Gene synonym":["TMPRSS4-AS1"],"Ensembl":"ENSG00000255274","Gene description":"Small integral membrane protein 35","Uniprot":["A0A1B0GVV1"],"Chromosome":"11","Position":"118003634-118088299","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1.2","kidney":"1.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Microglial cells":"17.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - T-cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"1.2","olfactory bulb":"3.5"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"7.9"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"}},{"Gene":"SMIM36","Gene synonym":[],"Ensembl":"ENSG00000261873","Gene description":"Small integral membrane protein 36","Uniprot":["A0A1B0GVT2"],"Chromosome":"17","Position":"55448433-55511444","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"6.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"13.3","Early spermatids":"15.8","Late spermatids":"4.8","Rod photoreceptor cells":"20.3","Spermatocytes":"12.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMIM38","Gene synonym":[],"Ensembl":"ENSG00000284713","Gene description":"Small integral membrane protein 38","Uniprot":["A0A286YFK9"],"Chromosome":"11","Position":"69155478-69159752","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"stomach 1":"22.8"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"1.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"3.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMIM39","Gene synonym":[],"Ensembl":"ENSG00000284479","Gene description":"Small integral membrane protein 39","Uniprot":["A0A1B0GW54"],"Chromosome":"2","Position":"131035092-131035262","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"5.1"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMIM4","Gene synonym":["C3orf78"],"Ensembl":"ENSG00000168273","Gene description":"Small integral membrane protein 4","Uniprot":["Q8WVI0"],"Chromosome":"3","Position":"52534013-52579237","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"121.9","skeletal muscle":"130.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"295.3","Distal tubular cells":"307.9","Proximal tubular cells":"256.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047771"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA047771":"AB_2680150"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.78e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.00e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"}},{"Gene":"SMIM40","Gene synonym":[],"Ensembl":"ENSG00000286920","Gene description":"Small integral membrane protein 40","Uniprot":[],"Chromosome":"6","Position":"33323628-33329279","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"467","RNA tissue specific nTPM":{"retina":"46.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Rod photoreceptor cells":"63.5"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMIM41","Gene synonym":[],"Ensembl":"ENSG00000284791","Gene description":"Small integral membrane protein 41","Uniprot":["A0A2R8YCJ5"],"Chromosome":"12","Position":"52079704-52108255","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"3.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Fibroblasts":"3.9","Leydig cells":"7.6","Peritubular cells":"15.0"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"56","RNA blood cell specific nTPM":{"plasmacytoid DC":"5.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"56","RNA blood lineage specific nTPM":{"dendritic cells":"5.5"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMIM42","Gene synonym":[],"Ensembl":"ENSG00000288460","Gene description":"Small integral membrane protein 42","Uniprot":[],"Chromosome":"1","Position":"158127287-158128301","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"No human protein\/transcript evidence","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"54","RNA tissue specific nTPM":{"testis":"5.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Early spermatids":"60.5"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMIM43","Gene synonym":[],"Ensembl":"ENSG00000164112","Gene description":"Small integral membrane protein 43","Uniprot":["Q4W5P6"],"Chromosome":"4","Position":"121758881-121765427","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"brain":"8.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"16.5","Excitatory neurons":"26.7","Inhibitory neurons":"8.8","Schwann cells":"7.9","Syncytiotrophoblasts":"6.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"basal ganglia":"8.3","cerebral cortex":"2.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"1.7"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"24.8"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"}},{"Gene":"SMIM5","Gene synonym":["C17orf109"],"Ensembl":"ENSG00000204323","Gene description":"Small integral membrane protein 5","Uniprot":["Q71RC9"],"Chromosome":"17","Position":"75633434-75641404","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"28.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"114.2","dendritic cells":"78.5","Distal tubular cells":"96.4","Endometrial ciliated cells":"72.7","Erythroid cells":"69.4","Glandular and luminal cells":"73.8","Schwann cells":"93.8","Suprabasal keratinocytes":"76.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"56","RNA blood cell specific nTPM":{"plasmacytoid DC":"207.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"56","RNA blood lineage specific nTPM":{"dendritic cells":"207.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Cardiomyocytes","Lung - Respiratory ciliated cells","Stomach - Gastric mucous cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065332","HPA071268"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA065332":"AB_2685471","HPA071268":"AB_2686377"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.52e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"}},{"Gene":"SMIM6","Gene synonym":["C17orf110","ELN"],"Ensembl":"ENSG00000259120","Gene description":"Small integral membrane protein 6","Uniprot":["P0DI80"],"Chromosome":"17","Position":"75646243-75647975","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"24.1","kidney":"22.1","stomach 1":"33.1","testis":"26.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"1360.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"12.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"42","RNA blood cell specific nTPM":{"plasmacytoid DC":"34.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"42","RNA blood lineage specific nTPM":{"dendritic cells":"34.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bile duct cancer":"7.9","colorectal cancer":"4.1","Gastric cancer":"9.6","Kidney cancer":"9.7","liver cancer":"6.1","lung cancer":"2.4","ovarian cancer":"3.9","pancreatic cancer":"6.7","Uterine cancer":"3.7"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Intercalated cells","Lung - Respiratory ciliated cells","Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065721"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA065721":"AB_2685546"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.49e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.64e-4"}},{"Gene":"SMIM7","Gene synonym":["C19orf42","MGC2747"],"Ensembl":"ENSG00000214046","Gene description":"Small integral membrane protein 7","Uniprot":["Q9BQ49"],"Chromosome":"19","Position":"16630751-16660442","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043127"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA043127":"AB_10806378"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"}},{"Gene":"SMIM8","Gene synonym":["C6orf162","dJ102H19.2","DKFZP586E1923"],"Ensembl":"ENSG00000111850","Gene description":"Small integral membrane protein 8","Uniprot":["Q96KF7"],"Chromosome":"6","Position":"87322583-87399749","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007401","HPA067453"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA007401":"AB_1078357","HPA067453":"AB_2685844"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"}},{"Gene":"SMIM9","Gene synonym":["CXorf68"],"Ensembl":"ENSG00000203870","Gene description":"Small integral membrane protein 9","Uniprot":["A6NGZ8"],"Chromosome":"X","Position":"154823348-154834662","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"29.4","Late spermatids":"8.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060970"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060970":"AB_2684399"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-5"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMLR1","Gene synonym":[],"Ensembl":"ENSG00000256162","Gene description":"Small leucine rich protein 1","Uniprot":["H3BR10"],"Chromosome":"6","Position":"130827406-130837135","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"56.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Hepatocytes":"321.2","Proximal enterocytes":"146.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"20","RNA cancer specific FPKM":{"liver cancer":"16.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"22","RNA cell line specific nTPM":{"liver cancer":"7.3"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066060"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066060":"AB_2685607"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SMO","Gene synonym":["FZD11","SMOH"],"Ensembl":"ENSG00000128602","Gene description":"Smoothened, frizzled class receptor","Uniprot":["Q99835"],"Chromosome":"7","Position":"129188633-129213545","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"26.6","Leydig cells":"20.3","Muller glia cells":"14.0","Peritubular cells":"22.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Liver - Hepatocytes","Lung - Fibroblast_2","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011446"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011446":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"}},{"Gene":"SMOC2","Gene synonym":["SMAP2"],"Ensembl":"ENSG00000112562","Gene description":"SPARC related modular calcium binding 2","Uniprot":["Q9H3U7"],"Chromosome":"6","Position":"168441151-168673445","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Leydig cells":"324.4","Peritubular cells":"769.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"18.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Pancreas - Fibroblasts","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hippocampal formation":"25.7"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"1.4"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.16e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-3"}},{"Gene":"SMOX","Gene synonym":["C20orf16","dJ779E11.1","FLJ20746","MGC1010","PAO","PAOh1","SMO"],"Ensembl":"ENSG00000088826","Gene description":"Spermine oxidase","Uniprot":["Q9NWM0"],"Chromosome":"20","Position":"4120980-4187747","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"61.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"37.3","Basal prostatic cells":"38.7","Ductal cells":"44.3","Erythroid cells":"44.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"1.0","myeloid DC":"2.4","neutrophil":"3.6","plasmacytoid DC":"1.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"2.4","granulocytes":"3.6","monocytes":"1.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047117","HPA060198"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear membrane","Vesicles","Cytosol"],"Antibody RRID":{"HPA047117":"AB_2679940","HPA060198":"AB_2684220"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.33e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"}},{"Gene":"SMPD1","Gene synonym":["ASM"],"Ensembl":"ENSG00000166311","Gene description":"Sphingomyelin phosphodiesterase 1","Uniprot":["P17405"],"Chromosome":"11","Position":"6390440-6394998","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Host-virus interaction","Lipid metabolism"],"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":["Disease variant","Neurodegeneration","Niemann-Pick disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"208.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.72e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.47e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.57e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"}},{"Gene":"SMPD2","Gene synonym":["ISC1","nSMase"],"Ensembl":"ENSG00000135587","Gene description":"Sphingomyelin phosphodiesterase 2","Uniprot":["O60906"],"Chromosome":"6","Position":"109440724-109443919","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"53.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"158.1","Late spermatids":"366.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018110","HPA018125"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA018110":"AB_1857292","HPA018125":"AB_1857293"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.17e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.70e-4"}},{"Gene":"SMPD3","Gene synonym":["NSMASE2"],"Ensembl":"ENSG00000103056","Gene description":"Sphingomyelin phosphodiesterase 3","Uniprot":["Q9NY59"],"Chromosome":"16","Position":"68358327-68448508","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Developmental protein","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"61.5","lymphoid tissue":"52.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"50.9","dendritic cells":"224.7","Gastric mucus-secreting cells":"62.0","Horizontal cells":"73.1","Proximal enterocytes":"104.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"8.0","basal ganglia":"29.7","cerebral cortex":"24.9","hippocampal formation":"25.4"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"plasmacytoid DC":"138.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"138.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"16.1"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Skin - Keratinocyte (granular)","Stomach - Gastric mucous cells","Testis - Peritubular cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"115.2"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"67.7"},"Antibody":["CAB033885","HPA065535","HPA069383"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB033885":"AB_1126788","HPA065535":null,"HPA069383":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.72e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.86e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"}},{"Gene":"SMPD4","Gene synonym":["FLJ20297","FLJ20756","KIAA1418","NET13","nSMase-3","NSMASE3"],"Ensembl":"ENSG00000136699","Gene description":"Sphingomyelin phosphodiesterase 4","Uniprot":["Q9NXE4"],"Chromosome":"2","Position":"130151392-130182750","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"18.4","Squamous epithelial cells":"17.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046279","HPA049426"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA046279":"AB_2679611","HPA049426":"AB_2680762"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.47e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.37e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.16e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"}},{"Gene":"SMPDL3B","Gene synonym":["ASML3B"],"Ensembl":"ENSG00000130768","Gene description":"Sphingomyelin phosphodiesterase acid like 3B","Uniprot":["Q92485"],"Chromosome":"1","Position":"27935000-27959157","Protein class":["Predicted secreted proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity","Lipid degradation","Lipid metabolism"],"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"24.1","pancreas":"49.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"35.0","Distal enterocytes":"46.5","Exocrine glandular cells":"32.0","Paneth cells":"56.0","Proximal enterocytes":"38.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"eosinophil":"3.3","myeloid DC":"1.3","neutrophil":"1.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"1.3","granulocytes":"3.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enterocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030561"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"400000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA030561":"AB_10604095"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-3"}},{"Gene":"SMYD4","Gene synonym":["KIAA1936","ZMYND21"],"Ensembl":"ENSG00000186532","Gene description":"SET and MYND domain containing 4","Uniprot":["Q8IYR2"],"Chromosome":"17","Position":"1779485-1830634","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Skeletal myocytes":"137.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030059"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA030059":"AB_2191728"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"}},{"Gene":"SNAP23","Gene synonym":["HsT17016","SNAP23A","SNAP23B"],"Ensembl":"ENSG00000092531","Gene description":"Synaptosome associated protein 23","Uniprot":["O00161"],"Chromosome":"15","Position":"42491233-42545356","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"340.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"675.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001214","CAB037083","CAB037317"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3900000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB037083":"AB_477494","CAB037317":"AB_261925","HPA001214":"AB_1080037"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"}},{"Gene":"SNAP47","Gene synonym":["C1orf142","SNAP-47","SVAP1"],"Ensembl":"ENSG00000143740","Gene description":"Synaptosome associated protein 47","Uniprot":["Q5SQN1"],"Chromosome":"1","Position":"227728200-227781826","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"100.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028167"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028167":"AB_10603032"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"}},{"Gene":"SNCAIP","Gene synonym":["SYPH1"],"Ensembl":"ENSG00000064692","Gene description":"Synuclein alpha interacting protein","Uniprot":["Q9Y6H5"],"Chromosome":"5","Position":"122311354-122464219","Protein class":["Disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"19.5","ovary":"37.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"81.9","Early spermatids":"75.5","Endometrial stromal cells":"56.4","Inhibitory neurons":"61.3","Oligodendrocyte precursor cells":"29.4","Thymic epithelial cells":"34.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"50","RNA blood cell specific nTPM":{"basophil":"7.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"50","RNA blood lineage specific nTPM":{"granulocytes":"7.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064687"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Cytoplasmic bodies"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA064687":"AB_2685324"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"}},{"Gene":"SNN","Gene synonym":[],"Ensembl":"ENSG00000184602","Gene description":"Stannin","Uniprot":["O75324"],"Chromosome":"16","Position":"11668455-11679152","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"126.0","skeletal muscle":"114.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"125.6","monocytes":"109.7","Muller glia cells":"141.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"62.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Gallbladder cancer":"119.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011055"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA011055":"AB_1857326"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.85e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.83e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"}},{"Gene":"SNORC","Gene synonym":["ASCL830","C2orf82","UNQ830"],"Ensembl":"ENSG00000182600","Gene description":"Secondary ossification center associated regulator of chondrocyte maturation","Uniprot":["Q6UX34"],"Chromosome":"2","Position":"232857270-232878708","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"55.0","breast":"14.2","skin 1":"32.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"398.3","Breast myoepithelial cells":"342.5","Distal enterocytes":"132.0","Hepatocytes":"114.5","Intestinal goblet cells":"129.9","Melanocytes":"214.2","Muller glia cells":"102.8","Undifferentiated cells":"151.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"7.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"20","RNA blood cell specific nTPM":{"basophil":"2.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"granulocytes":"2.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"9.7"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells (progenitors)","Liver - Hepatocytes","Skin - Eccrine sweat gland cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052824"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA052824":"AB_2681964"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.56e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"}},{"Gene":"SNPH","Gene synonym":["bA314N13.5"],"Ensembl":"ENSG00000101298","Gene description":"Syntaphilin","Uniprot":["O15079"],"Chromosome":"20","Position":"1266280-1309328","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"75.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"44.3","Bipolar cells":"24.8","Excitatory neurons":"59.7","Horizontal cells":"23.7","Inhibitory neurons":"70.2","Oligodendrocyte precursor cells":"36.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"1.0","naive CD8 T-cell":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"1.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049393"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytokinetic bridge","Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA049393":"AB_2680744"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.97e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"}},{"Gene":"SNRK","Gene synonym":["FLJ20224","HSNFRK","KIAA0096"],"Ensembl":"ENSG00000163788","Gene description":"SNF related kinase","Uniprot":["Q9NRH2"],"Chromosome":"3","Position":"43286512-43424764","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endothelial cells":"93.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042163"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles","Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA042163":"AB_10794645"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.28e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.41e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"}},{"Gene":"SNRNP40","Gene synonym":["HPRP8BP","PRP8BP","PRPF8BP","SPF38","WDR57"],"Ensembl":"ENSG00000060688","Gene description":"Small nuclear ribonucleoprotein U5 subunit 40","Uniprot":["Q96DI7"],"Chromosome":"1","Position":"31259568-31296788","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026527","HPA027345"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA026527":"AB_1858814","HPA027345":"AB_2239703"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.73e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"}},{"Gene":"SNTN","Gene synonym":["FLJ44379","S100AL"],"Ensembl":"ENSG00000188817","Gene description":"Sentan, cilia apical structure protein","Uniprot":["A6NMZ2"],"Chromosome":"3","Position":"63652675-63679020","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"fallopian tube":"173.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"513.4","Ionocytes":"142.5","Respiratory ciliated cells":"492.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"endometrial cancer":"1.9","lung cancer":"0.8","ovarian cancer":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1.0"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043322","HPA058399"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043322":"AB_10793945","HPA058399":"AB_2683705"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-3"}},{"Gene":"SNX13","Gene synonym":["KIAA0713","RGS-PX1"],"Ensembl":"ENSG00000071189","Gene description":"Sorting nexin 13","Uniprot":["Q9Y5W8"],"Chromosome":"7","Position":"17790761-17940501","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Signal transduction inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"218.2","Late spermatids":"275.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.98e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"}},{"Gene":"SNX14","Gene synonym":["RGS-PX2"],"Ensembl":"ENSG00000135317","Gene description":"Sorting nexin 14","Uniprot":["Q9Y5W7"],"Chromosome":"6","Position":"85505496-85594156","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"151.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017639"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017639":"AB_1857345"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"}},{"Gene":"SNX19","Gene synonym":["CHET8","KIAA0254"],"Ensembl":"ENSG00000120451","Gene description":"Sorting nexin 19","Uniprot":["Q92543"],"Chromosome":"11","Position":"130866250-130916479","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Exocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"106.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013447"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA013447":"AB_1857347"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.56e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"}},{"Gene":"SNX24","Gene synonym":["SBBI31"],"Ensembl":"ENSG00000064652","Gene description":"Sorting nexin 24","Uniprot":["Q9Y343"],"Chromosome":"5","Position":"122843439-123029354","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"106.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"3.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044566","HPA073934"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA044566":"AB_10797034","HPA073934":"AB_2686644"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.93e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.88e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.28e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"}},{"Gene":"SNX25","Gene synonym":["SBBI31"],"Ensembl":"ENSG00000109762","Gene description":"Sorting nexin 25","Uniprot":["Q9H3E2"],"Chromosome":"4","Position":"185204237-185370185","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"89.7","Astrocytes":"49.0","Excitatory neurons":"56.8","Inhibitory neurons":"59.2","Oligodendrocyte precursor cells":"52.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036928"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036928":"AB_10669720"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-3"}},{"Gene":"SOAT1","Gene synonym":["ACAT","SOAT","STAT"],"Ensembl":"ENSG00000057252","Gene description":"Sterol O-acyltransferase 1","Uniprot":["P35610"],"Chromosome":"1","Position":"179293714-179358680","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adrenal gland":"165.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Prostatic glandular cells":"95.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Prostate - Prostate glandular cells","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009533","HPA047171"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB009533":"AB_633499","HPA047171":"AB_2679967"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"}},{"Gene":"SOAT2","Gene synonym":["ACAT2"],"Ensembl":"ENSG00000167780","Gene description":"Sterol O-acyltransferase 2","Uniprot":["O75908"],"Chromosome":"12","Position":"53103486-53124535","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"19.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"17.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"liver cancer":"5.2","testis cancer":"5.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"1.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"5.6"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"}},{"Gene":"SOGA3","Gene synonym":["C6orf174","dJ403A15.3"],"Ensembl":"ENSG00000214338","Gene description":"SOGA family member 3","Uniprot":["Q5TF21"],"Chromosome":"6","Position":"127472794-127519191","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Excitatory neurons":"77.0","Inhibitory neurons":"56.1","Oligodendrocyte precursor cells":"42.4","Oligodendrocytes":"31.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"26.9"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Pancreas - Beta cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035388","HPA035389"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035388":"AB_2674601","HPA035389":"AB_10669857"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-3"}},{"Gene":"SORCS1","Gene synonym":[],"Ensembl":"ENSG00000108018","Gene description":"Sortilin related VPS10 domain containing receptor 1","Uniprot":["Q8WY21"],"Chromosome":"10","Position":"106573663-107164534","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.3","thyroid gland":"11.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"515.6","Inhibitory neurons":"175.8","Oligodendrocyte precursor cells":"365.3","Schwann cells":"103.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"3.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"25.7","Sarcoma":"13.4","skin cancer":"10.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Enteric glia cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011948"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA011948":"AB_1857366"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-4"}},{"Gene":"SORCS2","Gene synonym":["KIAA1329"],"Ensembl":"ENSG00000184985","Gene description":"Sortilin related VPS10 domain containing receptor 2","Uniprot":["Q96PQ0"],"Chromosome":"4","Position":"7192538-7742836","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"22.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"103.8","Bipolar cells":"69.8","Excitatory neurons":"40.8","Muller glia cells":"33.0","Oligodendrocytes":"72.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071818"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA071818":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.55e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-3"}},{"Gene":"SORCS3","Gene synonym":["KIAA1059","SORCS"],"Ensembl":"ENSG00000156395","Gene description":"Sortilin related VPS10 domain containing receptor 3","Uniprot":["Q9UPU3"],"Chromosome":"10","Position":"104641290-105265242","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"11.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Excitatory neurons":"266.5","Inhibitory neurons":"189.4","Oligodendrocyte precursor cells":"443.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"glioma":"1.8","renal cancer":"2.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.72e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SORL1","Gene synonym":["C11orf32","gp250","LR11","LRP9","SorLA","SorLA-1"],"Ensembl":"ENSG00000137642","Gene description":"Sortilin related receptor 1","Uniprot":["Q92673"],"Chromosome":"11","Position":"121452314-121633763","Protein class":["Disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Endocytosis","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Alzheimer disease","Amyloidosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"79.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"243.8","Microglial cells":"394.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"125.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"125.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Liver - Hepatocytes","Lung - Neutrophil_2","Prostate - Prostate basal glandular cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011500","HPA031321"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"79000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011500":"AB_443414","HPA031321":"AB_2673826"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.80e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"}},{"Gene":"SORT1","Gene synonym":["Gp95","NT3"],"Ensembl":"ENSG00000134243","Gene description":"Sortilin 1","Uniprot":["Q99523"],"Chromosome":"1","Position":"109309568-109397918","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Endocytosis","Osteogenesis","Transport"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"285.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"422.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"9.2","non-classical monocyte":"10.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006889","CAB011498"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":7170000,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB011498":"AB_2192606","HPA006889":"AB_1080056"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.74e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"}},{"Gene":"SOSTDC1","Gene synonym":["DAND7","DKFZp564D206","USAG1"],"Ensembl":"ENSG00000171243","Gene description":"Sclerostin domain containing 1","Uniprot":["Q6X4U4"],"Chromosome":"7","Position":"16461481-16530580","Protein class":["Predicted secreted proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"111.3","stomach 1":"60.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"67.1","Gastric mucus-secreting cells":"62.6","Melanocytes":"43.5","Proximal tubular cells":"23.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"25.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Skin - Outer root sheath cells","Stomach - Gastric mucous cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"9.2","hippocampal formation":"18.4","pons and medulla":"15.1","thalamus":"11.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042856"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Nucleoli rim","Golgi apparatus","Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoli","Nucleoli rim","Vesicles"],"Antibody RRID":{"HPA042856":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.69e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.22e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.72e-4"}},{"Gene":"SPAAR","Gene synonym":["LINC00961","SPAR"],"Ensembl":"ENSG00000235387","Gene description":"Small regulatory polypeptide of amino acid response","Uniprot":["A0A1B0GVQ0"],"Chromosome":"9","Position":"35909490-35937153","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"12.4","breast":"10.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"38.2","Alveolar cells type 1":"6.7","Endothelial cells":"15.1","Sertoli cells":"5.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"2.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"10.9","Sarcoma":"4.3"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Skin - Endothelial cells","Stomach - Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"}},{"Gene":"SPACA1","Gene synonym":["SAMP32"],"Ensembl":"ENSG00000118434","Gene description":"Sperm acrosome associated 1","Uniprot":["Q9HBV2"],"Chromosome":"6","Position":"88047841-88066838","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"371","RNA tissue specific nTPM":{"testis":"41.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"22","RNA single cell type specific nTPM":{"Early spermatids":"1202.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026744","HPA043297"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026744":"AB_2194642","HPA043297":"AB_2678413"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPACA3","Gene synonym":["ALLP17","CT54","LYC3","LYZL3","SLLP1"],"Ensembl":"ENSG00000141316","Gene description":"Sperm acrosome associated 3","Uniprot":["Q8IXA5"],"Chromosome":"17","Position":"32970376-32997877","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"125.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"95","RNA single cell type specific nTPM":{"Early spermatids":"1273.8","Late spermatids":"1117.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"0.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory B-cell":"1.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"1.2"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"18","RNA cell line specific nTPM":{"Myeloma":"9.4"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023633"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023633":"AB_1857407"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-4"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-1"}},{"Gene":"SPACA4","Gene synonym":["SAMP14"],"Ensembl":"ENSG00000177202","Gene description":"Sperm acrosome associated 4","Uniprot":["Q8TDM5"],"Chromosome":"19","Position":"48606742-48607714","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"testis":"117.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"87","RNA single cell type specific nTPM":{"Early spermatids":"935.7","Late spermatids":"369.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Prostate - Urothelial cells","Stomach - Gastric mucous cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041927","HPA061302"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041927":"AB_10794162","HPA061302":"AB_2684475"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-6"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"}},{"Gene":"SPACA6","Gene synonym":["LET7EH","LINC00085","NCRNA00085","SPACA6P"],"Ensembl":"ENSG00000182310","Gene description":"Sperm acrosome associated 6","Uniprot":["W5XKT8"],"Chromosome":"19","Position":"51689128-51712387","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fertilization"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"2.5","testis":"7.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"104.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.73e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.98e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"}},{"Gene":"SPAG4","Gene synonym":["CT127","SUN4"],"Ensembl":"ENSG00000061656","Gene description":"Sperm associated antigen 4","Uniprot":["Q9NPE6"],"Chromosome":"20","Position":"35615829-35621094","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"pancreas":"90.1","testis":"32.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"144.1","Late spermatids":"168.8","Plasma cells":"209.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Plasma cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048393","HPA061789"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048393":"AB_2680385","HPA061789":"AB_2684609"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.52e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.31e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.28e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.66e-4"}},{"Gene":"SPAG5","Gene synonym":["DEEPEST","hMAP126","MAP126"],"Ensembl":"ENSG00000076382","Gene description":"Sperm associated antigen 5","Uniprot":["Q96R06"],"Chromosome":"17","Position":"28577565-28599025","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"37.9","kidney":"37.8","testis":"74.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"113.1","Erythroid cells":"31.4","Late spermatids":"34.8","Spermatocytes":"62.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"11.7","T-reg":"4.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"11.7","T-cells":"4.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022008","HPA022479","HPA024418"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Mitotic spindle","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nuclear bodies","Mitotic spindle"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA022008":"AB_1853519","HPA022479":"AB_1853521","HPA024418":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.43e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.43e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"}},{"Gene":"SPAG9","Gene synonym":["CT89","FLJ13450","FLJ14006","FLJ26141","FLJ34602","HLC4","HSS","JIP-4","JIP4","JLP","KIAA0516","MGC117291","MGC14967","MGC74461","PHET","PIG6","SYD1"],"Ensembl":"ENSG00000008294","Gene description":"Sperm associated antigen 9","Uniprot":["O60271"],"Chromosome":"17","Position":"50962174-51120868","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"9.2","neutrophil":"12.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"12.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040446","HPA061458"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Centriolar satellite","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA040446":"AB_10671691","HPA061458":"AB_2684528"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.10e-4"}},{"Gene":"SPAM1","Gene synonym":["HYAL5","PH-20","SPAG15"],"Ensembl":"ENSG00000106304","Gene description":"Sperm adhesion molecule 1","Uniprot":["P38567"],"Chromosome":"7","Position":"123925237-123971414","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"38","RNA tissue specific nTPM":{"testis":"17.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"87","RNA single cell type specific nTPM":{"Early spermatids":"311.3","Late spermatids":"123.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017984"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017984":"AB_1857413"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPAST","Gene synonym":["ADPSP","FSP2","KIAA1083","SPG4"],"Ensembl":"ENSG00000021574","Gene description":"Spastin","Uniprot":["Q9UBP0"],"Chromosome":"2","Position":"32063556-32157637","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cell cycle","Cell division","Differentiation","Neurogenesis"],"Molecular function":["Allosteric enzyme","Developmental protein","Isomerase"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"59.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017311"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA017311":"AB_1857415"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.15e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"}},{"Gene":"SPATA25","Gene synonym":["C20orf165","dJ337O18.8","TSG23"],"Ensembl":"ENSG00000149634","Gene description":"Spermatogenesis associated 25","Uniprot":["Q9BR10"],"Chromosome":"20","Position":"45886489-45887635","Protein class":["Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"24.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"128","RNA single cell type specific nTPM":{"Early spermatids":"317.3","Late spermatids":"88.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041386"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA041386":"AB_2677446"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"}},{"Gene":"SPATA3","Gene synonym":["TSARG1"],"Ensembl":"ENSG00000173699","Gene description":"Spermatogenesis associated 3","Uniprot":["Q8NHX4"],"Chromosome":"2","Position":"230990324-231025055","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"179","RNA tissue specific nTPM":{"testis":"176.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Late spermatids":"5292.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Eccrine sweat gland cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018254"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018254":"AB_1857419"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPATA31A1","Gene synonym":["C9orf36","C9orf36A","DKFZP434B204","FAM75A1","FAM75A2","SPATA31A2"],"Ensembl":"ENSG00000204849","Gene description":"SPATA31 subfamily A member 1","Uniprot":["Q5TZJ5"],"Chromosome":"9","Position":"39355669-39361962","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"90","RNA tissue specific nTPM":{"testis":"8.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"17.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPATA31A3","Gene synonym":["DKFZp434B204","FAM75A3"],"Ensembl":"ENSG00000275969","Gene description":"SPATA31 subfamily A member 3","Uniprot":["Q5VYP0"],"Chromosome":"9","Position":"66986304-66992583","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"48","RNA tissue specific nTPM":{"testis":"4.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPATA31A5","Gene synonym":["FAM75A5"],"Ensembl":"ENSG00000276581","Gene description":"SPATA31 subfamily A member 5","Uniprot":["Q5VU36"],"Chromosome":"9","Position":"60914407-60920653","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"testis":"1.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPATA31A6","Gene synonym":["FAM75A6"],"Ensembl":"ENSG00000185775","Gene description":"SPATA31 subfamily A member 6","Uniprot":["Q5VVP1"],"Chromosome":"9","Position":"42183659-42189887","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"testis":"2.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPATA31A7","Gene synonym":["FAM75A4","FAM75A7","SPATA31A4"],"Ensembl":"ENSG00000276040","Gene description":"SPATA31 subfamily A member 7","Uniprot":["Q8IWB4"],"Chromosome":"9","Position":"61190003-61196280","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"testis":"2.9"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPATA31D1","Gene synonym":["FAM75D1","FLJ46321"],"Ensembl":"ENSG00000214929","Gene description":"SPATA31 subfamily D member 1","Uniprot":["Q6ZQQ2"],"Chromosome":"9","Position":"81988772-81995253","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"112","RNA tissue specific nTPM":{"testis":"11.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"65.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047897"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047897":"AB_2680204"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPATA31D3","Gene synonym":["FAM75D3","FLJ44082"],"Ensembl":"ENSG00000186788","Gene description":"SPATA31 subfamily D member 3","Uniprot":["P0C874"],"Chromosome":"9","Position":"81943586-81950038","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"81","RNA tissue specific nTPM":{"testis":"8.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"29.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPATA31D4","Gene synonym":["FAM75D4","FLJ43859"],"Ensembl":"ENSG00000189357","Gene description":"SPATA31 subfamily D member 4","Uniprot":["Q6ZUB0"],"Chromosome":"9","Position":"81928514-81934948","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"61","RNA tissue specific nTPM":{"testis":"6.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Early spermatids":"27.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPATA31E1","Gene synonym":["C9orf79","FAM75E1","FLJ35866"],"Ensembl":"ENSG00000177992","Gene description":"SPATA31 subfamily E member 1","Uniprot":["Q6ZUB1"],"Chromosome":"9","Position":"87882877-87888903","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"76","RNA tissue specific nTPM":{"brain":"7.5","testis":"7.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"61","RNA single cell type specific nTPM":{"Early spermatids":"23.2","Late spermatids":"26.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"13","RNA brain regional specific nTPM":{"hippocampal formation":"7.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024253"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024253":"AB_1845839"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPATA5L1","Gene synonym":["FLJ12286","MGC5347"],"Ensembl":"ENSG00000171763","Gene description":"Spermatogenesis associated 5 like 1","Uniprot":["Q9BVQ7"],"Chromosome":"15","Position":"45402336-45421415","Protein class":["Predicted intracellular proteins"],"Biological process":["Ribosome biogenesis"],"Molecular function":["Hydrolase"],"Disease involvement":["Deafness","Epilepsy","Intellectual disability","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043679"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA043679":"AB_10964179"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.88e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"}},{"Gene":"SPATA7","Gene synonym":["HSD3","LCA3"],"Ensembl":"ENSG00000042317","Gene description":"Spermatogenesis associated 7","Uniprot":["Q9P0W8"],"Chromosome":"14","Position":"88384924-88470350","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Leber congenital amaurosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"57.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Early spermatids":"766.4","Late spermatids":"1261.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038082","HPA038083"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038082":"AB_10671738","HPA038083":"AB_10671519"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.16e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.50e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"}},{"Gene":"SPATA9","Gene synonym":["FLJ35906","NYD-SP16"],"Ensembl":"ENSG00000145757","Gene description":"Spermatogenesis associated 9","Uniprot":["Q9BWV2"],"Chromosome":"5","Position":"95652181-95698711","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"testis":"26.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Early spermatids":"530.9","Late spermatids":"574.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010848","HPA076967"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA010848":"AB_1857422","HPA076967":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"}},{"Gene":"SPCS1","Gene synonym":["HSPC033","SPC1","SPC12","YJR010C-A"],"Ensembl":"ENSG00000114902","Gene description":"Signal peptidase complex subunit 1","Uniprot":["Q9Y6A9"],"Chromosome":"3","Position":"52704955-52711148","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"1199.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046091","HPA055273"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046091":"AB_10959614","HPA055273":"AB_2682768"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.28e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"}},{"Gene":"SPCS2","Gene synonym":["KIAA0102"],"Ensembl":"ENSG00000118363","Gene description":"Signal peptidase complex subunit 2","Uniprot":["Q15005"],"Chromosome":"11","Position":"74949247-74979033","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"964.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013386"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA013386":"AB_1857426"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"}},{"Gene":"SPCS3","Gene synonym":["FLJ22649","PRO3567","SPC22\/23","SPC3","YLR066W"],"Ensembl":"ENSG00000129128","Gene description":"Signal peptidase complex subunit 3","Uniprot":["P61009"],"Chromosome":"4","Position":"176319966-176332245","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"741.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053180"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053180":"AB_2682071"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.89e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.87e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"}},{"Gene":"SPEM1","Gene synonym":["C17orf83","FLJ40081"],"Ensembl":"ENSG00000181323","Gene description":"Spermatid maturation 1","Uniprot":["Q8N4L4"],"Chromosome":"17","Position":"7420324-7421632","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"333","RNA tissue specific nTPM":{"testis":"68.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Late spermatids":"3817.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPEM2","Gene synonym":["C17orf74"],"Ensembl":"ENSG00000184560","Gene description":"SPEM family member 2","Uniprot":["Q0P670"],"Chromosome":"17","Position":"7425616-7427568","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"571","RNA tissue specific nTPM":{"testis":"128.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Late spermatids":"2361.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023649"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA023649":"AB_1845606"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-4"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPEM3","Gene synonym":[],"Ensembl":"ENSG00000283439","Gene description":"SPEM family member 3","Uniprot":["A0A1B0GUW6"],"Chromosome":"17","Position":"7428857-7432820","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"564","RNA tissue specific nTPM":{"testis":"56.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"100","RNA single cell type specific nTPM":{"Early spermatids":"78.6","Late spermatids":"84.1"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPG11","Gene synonym":["ALS5","FLJ21439","KIAA1840"],"Ensembl":"ENSG00000104133","Gene description":"SPG11 vesicle trafficking associated, spatacsin","Uniprot":["Q96JI7"],"Chromosome":"15","Position":"44562696-44663678","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Charcot-Marie-Tooth disease","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040412","HPA040947"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA040412":"AB_10795418","HPA040947":"AB_10796232"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.28e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"}},{"Gene":"SPG7","Gene synonym":["CAR","CMAR","SPG5C"],"Ensembl":"ENSG00000197912","Gene description":"SPG7 matrix AAA peptidase subunit, paraplegin","Uniprot":["Q9UQ90"],"Chromosome":"16","Position":"89490719-89557766","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.91e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.25e-4"}},{"Gene":"SPI1","Gene synonym":["OF","PU.1","SFPI1","SPI-1","SPI-A"],"Ensembl":"ENSG00000066336","Gene description":"Spi-1 proto-oncogene","Uniprot":["P17947"],"Chromosome":"11","Position":"47354860-47378547","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","RNA-binding"],"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"335.1","lung":"101.0","lymphoid tissue":"172.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hofbauer cells":"490.5","Kupffer cells":"283.2","Langerhans cells":"617.7","Macrophages":"432.6","monocytes":"546.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"179.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"179.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"Leukemia":"124.1","lymphoma":"61.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Lung - Neutrophil_2","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Langerhans cells","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004079","HPA044653"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB004079":"AB_10692379","HPA044653":"AB_2679036"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.07e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"}},{"Gene":"SPIDR","Gene synonym":["KIAA0146"],"Ensembl":"ENSG00000164808","Gene description":"Scaffold protein involved in DNA repair","Uniprot":["Q14159"],"Chromosome":"8","Position":"47260878-47736306","Protein class":["Predicted intracellular proteins"],"Biological process":["DNA damage","DNA recombination","DNA repair"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"118.6","Excitatory neurons":"251.7","Inhibitory neurons":"209.5","Microglial cells":"210.7","Oligodendrocyte precursor cells":"198.8","Oligodendrocytes":"133.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027201","HPA041582"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA027201":"AB_10603774","HPA041582":"AB_2677563"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.91e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.04e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"}},{"Gene":"SPIN3","Gene synonym":["TDRD27"],"Ensembl":"ENSG00000204271","Gene description":"Spindlin family member 3","Uniprot":["Q5JUX0"],"Chromosome":"X","Position":"56818298-56995827","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"23.5","Inhibitory neurons":"22.8","Oligodendrocyte precursor cells":"24.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000727"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA000727":"AB_2196121"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.49e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.79e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.30e-4"}},{"Gene":"SPINT1","Gene synonym":["HAI","MANSC2"],"Ensembl":"ENSG00000166145","Gene description":"Serine peptidase inhibitor, Kunitz type 1","Uniprot":["O43278"],"Chromosome":"15","Position":"40844018-40858207","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"255.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"1223.0","Proximal enterocytes":"474.3","Syncytiotrophoblasts":"1720.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enterocytes","Liver - Cholangiocyte","Lung - Alveolar cells type 2","Stomach - Gastric mucous cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006903","HPA031178"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7400000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA006903":"AB_1079038","HPA031178":"AB_2732463"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.97e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.37e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"}},{"Gene":"SPINT2","Gene synonym":["HAI-2","Kop"],"Ensembl":"ENSG00000167642","Gene description":"Serine peptidase inhibitor, Kunitz type 2","Uniprot":["O43291"],"Chromosome":"19","Position":"38244035-38292615","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"1399.1","Syncytiotrophoblasts":"1398.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011101","CAB018969"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Intermediate filaments","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Plasma membrane","Intermediate filaments","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB018969":null,"HPA011101":"AB_1079039"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.41e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"}},{"Gene":"SPNS1","Gene synonym":["HSpin1","LAT","nrs","PP2030","SLC62A1","SPIN1","SPINL"],"Ensembl":"ENSG00000169682","Gene description":"Sphingolipid transporter 1 (putative)","Uniprot":["Q9H2V7"],"Chromosome":"16","Position":"28974221-28984548","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"21.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041995","HPA042988"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Golgi apparatus","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoli fibrillar center","Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA041995":"AB_10959609","HPA042988":"AB_10964587"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"}},{"Gene":"SPNS2","Gene synonym":["SLC62A2"],"Ensembl":"ENSG00000183018","Gene description":"Sphingolipid transporter 2","Uniprot":["Q8IVW8"],"Chromosome":"17","Position":"4498881-4539035","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"51.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"36.1","Endothelial cells":"39.2","Extravillous trophoblasts":"35.4","Gastric mucus-secreting cells":"32.2","Microglial cells":"36.5","Oligodendrocytes":"92.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Heart muscle - Endothelial cells","Lung - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Keratinocyte (granular)","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068717"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA068717":"AB_2686021"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"}},{"Gene":"SPNS3","Gene synonym":["MGC29671","SLC62A3"],"Ensembl":"ENSG00000182557","Gene description":"Sphingolipid transporter 3 (putative)","Uniprot":["Q6ZMD2"],"Chromosome":"17","Position":"4433940-4488208","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"bone marrow":"31.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"62.2","Langerhans cells":"19.4","monocytes":"14.2","Proximal tubular cells":"45.8","T-cells":"21.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"2.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"eosinophil":"354.8","plasmacytoid DC":"127.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"37","RNA blood lineage specific nTPM":{"dendritic cells":"127.7","granulocytes":"354.8"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"39.3"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Prostate - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023928"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023928":"AB_1844393"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"}},{"Gene":"SPPL2A","Gene synonym":["IMP3","PSL2"],"Ensembl":"ENSG00000138600","Gene description":"Signal peptide peptidase like 2A","Uniprot":["Q8TCT8"],"Chromosome":"15","Position":"50702266-50765709","Protein class":["Enzymes","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Skeletal myocytes":"248.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036062","HPA067304"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036062":"AB_10611670","HPA067304":"AB_2685820"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"}},{"Gene":"SPPL2B","Gene synonym":["IMP4","KIAA1532","PSL1"],"Ensembl":"ENSG00000005206","Gene description":"Signal peptide peptidase like 2B","Uniprot":["Q8TCT7"],"Chromosome":"19","Position":"2328615-2355095","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"102.0","Late spermatids":"104.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005592","HPA039292"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"CAB005592":"AB_325074","HPA039292":"AB_2676429"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.00e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"}},{"Gene":"SPPL2C","Gene synonym":["IMP5"],"Ensembl":"ENSG00000185294","Gene description":"Signal peptide peptidase like 2C","Uniprot":["Q8IUH8"],"Chromosome":"17","Position":"45844881-45847067","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"73","RNA tissue specific nTPM":{"testis":"36.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"619.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077339"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA077339":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-4"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SPPL3","Gene synonym":["DKFZP586C1324","IMP2","MGC126674","MGC126676","MGC90402","PSL4"],"Ensembl":"ENSG00000157837","Gene description":"Signal peptide peptidase like 3","Uniprot":["Q8TCT6"],"Chromosome":"12","Position":"120762510-120904358","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"181.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Early spermatids","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004194","HPA059958"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA004194":"AB_2667171","HPA059958":"AB_2684179"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"}},{"Gene":"SPRED1","Gene synonym":["FLJ33903","PPP1R147"],"Ensembl":"ENSG00000166068","Gene description":"Sprouty related EVH1 domain containing 1","Uniprot":["Q7Z699"],"Chromosome":"15","Position":"38252836-38357249","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"168.3","Excitatory neurons":"161.2","Microglial cells":"194.3","Oligodendrocyte precursor cells":"266.2","Oligodendrocytes":"138.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"monocytes":"1.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042193","HPA061805"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA042193":"AB_10794079","HPA061805":"AB_2684617"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.08e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.37e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.29e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"}},{"Gene":"SPRED2","Gene synonym":["FLJ21897","FLJ31917","Spred-2"],"Ensembl":"ENSG00000198369","Gene description":"Sprouty related EVH1 domain containing 2","Uniprot":["Q7Z698"],"Chromosome":"2","Position":"65310851-65432637","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"105.3","Excitatory neurons":"136.6","Inhibitory neurons":"119.5","Oligodendrocyte precursor cells":"118.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"NK-cell":"1.9","plasmacytoid DC":"4.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"4.2","NK-cells":"1.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038256","HPA064394"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA038256":null,"HPA064394":"AB_2732712"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"}},{"Gene":"SPRED3","Gene synonym":[],"Ensembl":"ENSG00000188766","Gene description":"Sprouty related EVH1 domain containing 3","Uniprot":["Q2MJR0"],"Chromosome":"19","Position":"38388421-38399587","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.0","pituitary gland":"5.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"11.2","Excitatory neurons":"9.7","Horizontal cells":"7.0","Inhibitory neurons":"10.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071521"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA071521":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-3"}},{"Gene":"SPRY1","Gene synonym":["hSPRY1"],"Ensembl":"ENSG00000164056","Gene description":"Sprouty RTK signaling antagonist 1","Uniprot":["O43609"],"Chromosome":"4","Position":"123396795-123403760","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"238.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"816.2","Endothelial cells":"371.4","Fibroblasts":"221.9","Leydig cells":"411.8","Thymic epithelial cells":"318.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"61.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Liver - Hepatic stellate cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013538","HPA051369","HPA070554"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB013538":"AB_2533452","HPA051369":"AB_2681457","HPA070554":"AB_2686280"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"}},{"Gene":"SPRY2","Gene synonym":["hSPRY2"],"Ensembl":"ENSG00000136158","Gene description":"Sprouty RTK signaling antagonist 2","Uniprot":["O43597"],"Chromosome":"13","Position":"80335976-80341126","Protein class":["Disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"81.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"4.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037205","HPA042198"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Actin filaments","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Actin filaments","Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB037205":"AB_261923","HPA042198":"AB_2677896"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"}},{"Gene":"SPRY3","Gene synonym":["HSPRY3"],"Ensembl":"ENSG00000168939","Gene description":"Sprouty RTK signaling antagonist 3","Uniprot":["O43610"],"Chromosome":"X","Position":"155612572-155782459","Protein class":["Predicted membrane proteins"],"Biological process":["Neurogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"41.4","Excitatory neurons":"40.4","Inhibitory neurons":"42.5","Microglial cells":"61.1","Oligodendrocyte precursor cells":"30.8","Oligodendrocytes":"19.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013505"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB013505":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"}},{"Gene":"SPRY4","Gene synonym":[],"Ensembl":"ENSG00000187678","Gene description":"Sprouty RTK signaling antagonist 4","Uniprot":["Q9C004"],"Chromosome":"5","Position":"142310427-142326455","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism","Kallmann syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"36.0","Alveolar cells type 2":"56.8","Endothelial cells":"32.4","Oligodendrocyte precursor cells":"92.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"73.5"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008086","HPA055471","HPA072661"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB008086":"AB_2195454","HPA055471":"AB_2682825","HPA072661":"AB_2732207"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.12e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"}},{"Gene":"SPTAN1","Gene synonym":[],"Ensembl":"ENSG00000197694","Gene description":"Spectrin alpha, non-erythrocytic 1","Uniprot":["Q13813"],"Chromosome":"9","Position":"128552558-128633662","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin capping","Actin-binding","Calmodulin-binding"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004581","HPA007927"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Vesicles","Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB004581":"AB_671135","HPA007927":"AB_1857435"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.84e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"}},{"Gene":"SPTLC1","Gene synonym":["hLCB1","HSAN1","HSN1","LCB1","SPTI"],"Ensembl":"ENSG00000090054","Gene description":"Serine palmitoyltransferase long chain base subunit 1","Uniprot":["O15269"],"Chromosome":"9","Position":"92000087-92115413","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010860","CAB018747","HPA063907"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB018747":"AB_2195864","HPA010860":"AB_1080086","HPA063907":"AB_2685148"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.36e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"}},{"Gene":"SPTLC3","Gene synonym":["C20orf38","FLJ11112","hLCB2b","LCB2B","SPTLC2L"],"Ensembl":"ENSG00000172296","Gene description":"Serine palmitoyltransferase long chain base subunit 3","Uniprot":["Q9NUV7"],"Chromosome":"20","Position":"13008972-13169103","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"28.0","Early spermatids":"31.5","Glandular and luminal cells":"47.7","Microglial cells":"34.7","Syncytiotrophoblasts":"57.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044247","HPA048079"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA044247":"AB_2678872","HPA048079":"AB_2680252"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.02e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.51e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"}},{"Gene":"SPTSSA","Gene synonym":["C14orf147","ssSPTa"],"Ensembl":"ENSG00000165389","Gene description":"Serine palmitoyltransferase small subunit A","Uniprot":["Q969W0"],"Chromosome":"14","Position":"34432788-34462240","Protein class":["Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Melanocytes":"463.3","Syncytiotrophoblasts":"569.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"}},{"Gene":"SPTSSB","Gene synonym":["ADMP","C3orf57","ssSPTb"],"Ensembl":"ENSG00000196542","Gene description":"Serine palmitoyltransferase small subunit B","Uniprot":["Q8NFR3"],"Chromosome":"3","Position":"161344792-161372880","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"45.5","stomach 1":"61.4","urinary bladder":"49.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"48.8","Excitatory neurons":"28.1","Gastric mucus-secreting cells":"34.0","Melanocytes":"55.7","Prostatic glandular cells":"74.3","Suprabasal keratinocytes":"28.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"24.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"NK-cell":"353.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"NK-cells":"353.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"150.3","Gallbladder cancer":"98.5"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047712"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA047712":"AB_2680127"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-3"}},{"Gene":"SPTY2D1OS","Gene synonym":["SPTY2D1-AS1"],"Ensembl":"ENSG00000247595","Gene description":"SPTY2D1 opposite strand","Uniprot":["A0A0U1RRN3"],"Chromosome":"11","Position":"18588781-18610255","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"34","RNA tissue specific nTPM":{"testis":"487.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"10618.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"}},{"Gene":"SQLE","Gene synonym":[],"Ensembl":"ENSG00000104549","Gene description":"Squalene epoxidase","Uniprot":["Q14534"],"Chromosome":"8","Position":"124998497-125022283","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"228.5","Syncytiotrophoblasts":"301.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018038","HPA020762"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 26: NCI-H716 - Unknown function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA018038":"AB_2669753","HPA020762":"AB_2670512"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.42e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.67e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-3"}},{"Gene":"SQSTM1","Gene synonym":["A170","OSIL","p60","p62","p62B","PDB3"],"Ensembl":"ENSG00000161011","Gene description":"Sequestosome 1","Uniprot":["Q13501"],"Chromosome":"5","Position":"179806398-179838078","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Autophagy","Differentiation","Immunity"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"1183.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"2551.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004587","HPA064165","HPA068843"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"81000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004587":"AB_628279","HPA064165":"AB_2685203","HPA068843":"AB_2732120"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.31e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"}},{"Gene":"SRD5A1","Gene synonym":[],"Ensembl":"ENSG00000145545","Gene description":"Steroid 5 alpha-reductase 1","Uniprot":["P18405"],"Chromosome":"5","Position":"6633427-6674386","Protein class":["Cancer-related genes","Enzymes","FDA approved drug targets","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Lipid metabolism","Sexual differentiation"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"29.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"99.7","Hepatocytes":"97.9","Squamous epithelial cells":"140.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"3.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051402"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051402":"AB_2681470"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.73e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"}},{"Gene":"SRD5A2","Gene synonym":[],"Ensembl":"ENSG00000277893","Gene description":"Steroid 5 alpha-reductase 2","Uniprot":["P31213"],"Chromosome":"2","Position":"31522480-31580938","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Lipid metabolism","Sexual differentiation"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Pseudohermaphroditism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"epididymis":"23.5","fallopian tube":"20.4","liver":"60.8","prostate":"16.8","seminal vesicle":"18.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Club cells":"21.0","Early spermatids":"54.4","Endometrial ciliated cells":"26.6","Hepatocytes":"21.2","Late spermatids":"71.9","Respiratory ciliated cells":"18.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"endometrial cancer":"1.1","liver cancer":"4.2","prostate cancer":"3.2"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"11","RNA brain regional specific nTPM":{"midbrain":"1.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes","Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-3"}},{"Gene":"SRD5A3","Gene synonym":["FLJ13352","SRD5A2L","SRD5A2L1"],"Ensembl":"ENSG00000128039","Gene description":"Steroid 5 alpha-reductase 3","Uniprot":["Q9H8P0"],"Chromosome":"4","Position":"55346213-55373100","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cataract","Congenital disorder of glycosylation","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ionocytes":"25.4","Oligodendrocytes":"22.1","Respiratory ciliated cells":"23.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027006"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027006":"AB_1857469"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.39e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.80e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.85e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"}},{"Gene":"SREBF1","Gene synonym":["bHLHd1","SREBP-1c","SREBP1","SREBP1a"],"Ensembl":"ENSG00000072310","Gene description":"Sterol regulatory element binding transcription factor 1","Uniprot":["P36956"],"Chromosome":"17","Position":"17810399-17837011","Protein class":["Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"219.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005406","HPA043343","HPA043878"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005406":"AB_2194226","HPA043343":"AB_2678439","HPA043878":"AB_2678710"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.66e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.05e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-3"}},{"Gene":"SREBF2","Gene synonym":["bHLHd2","SREBP2"],"Ensembl":"ENSG00000198911","Gene description":"Sterol regulatory element binding transcription factor 2","Uniprot":["Q12772"],"Chromosome":"22","Position":"41833079-41907307","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Cholesterol metabolism","Lipid metabolism","Steroid metabolism","Sterol metabolism","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031962","HPA031963"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA031962":"AB_10601266","HPA031963":"AB_2674090"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.37e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-3"}},{"Gene":"SRM","Gene synonym":["SPS1","SRML1"],"Ensembl":"ENSG00000116649","Gene description":"Spermidine synthase","Uniprot":["P19623"],"Chromosome":"1","Position":"11054584-11060020","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Polyamine biosynthesis","Spermidine biosynthesis"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"473.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015746"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"26000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA015746":"AB_1857472"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.25e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.80e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"}},{"Gene":"SRP9","Gene synonym":[],"Ensembl":"ENSG00000143742","Gene description":"Signal recognition particle 9","Uniprot":["P49458"],"Chromosome":"1","Position":"225777813-225790468","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":["Ribonucleoprotein","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"22000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"}},{"Gene":"SRPRA","Gene synonym":["SR-alpha","Sralpha","SRP-alpha","SRPR"],"Ensembl":"ENSG00000182934","Gene description":"SRP receptor subunit alpha","Uniprot":["P08240"],"Chromosome":"11","Position":"126262938-126269144","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"246.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.56e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"}},{"Gene":"SRPRB","Gene synonym":["APMCF1","SR-beta"],"Ensembl":"ENSG00000144867","Gene description":"SRP receptor subunit beta","Uniprot":["Q9Y5M8"],"Chromosome":"3","Position":"133784023-133825772","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"189.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011173"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA011173":"AB_1857484"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.12e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"}},{"Gene":"SSBP2","Gene synonym":["HSPC116"],"Ensembl":"ENSG00000145687","Gene description":"Single stranded DNA binding protein 2","Uniprot":["P81877"],"Chromosome":"5","Position":"81413021-81751797","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"273.0","Excitatory neurons":"259.2","Inhibitory neurons":"341.4","Microglial cells":"330.2","Oligodendrocytes":"321.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB020834","HPA068605","HPA071780"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB020834":null,"HPA068605":"AB_2732116","HPA071780":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"}},{"Gene":"SSMEM1","Gene synonym":["C7orf45","FLJ40316"],"Ensembl":"ENSG00000165120","Gene description":"Serine rich single-pass membrane protein 1","Uniprot":["Q8WWF3"],"Chromosome":"7","Position":"130206344-130216844","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"159","RNA tissue specific nTPM":{"testis":"32.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Early spermatids":"595.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SSPN","Gene synonym":["KRAG","SPN1","SPN2"],"Ensembl":"ENSG00000123096","Gene description":"Sarcospan","Uniprot":["Q14714"],"Chromosome":"12","Position":"26121991-26299290","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"79.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"112.0","Fibroblasts":"138.9","Leydig cells":"188.9","Peritubular cells":"269.9","Skeletal myocytes":"172.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"memory B-cell":"57.4","naive B-cell":"16.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"B-cells":"57.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Liver - Hepatic stellate cells","Prostate - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066432"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA066432":"AB_2685669"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"}},{"Gene":"SSR1","Gene synonym":["TRAPA"],"Ensembl":"ENSG00000124783","Gene description":"Signal sequence receptor subunit 1","Uniprot":["P43307"],"Chromosome":"6","Position":"7268306-7347446","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011276","HPA017062"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA011276":"AB_1857503","HPA017062":"AB_1857505"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.92e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.79e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"}},{"Gene":"SSR2","Gene synonym":["TLAP","TRAPB"],"Ensembl":"ENSG00000163479","Gene description":"Signal sequence receptor subunit 2","Uniprot":["P43308"],"Chromosome":"1","Position":"156009048-156020951","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"62000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.00e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"}},{"Gene":"SSR3","Gene synonym":["TRAPG"],"Ensembl":"ENSG00000114850","Gene description":"Signal sequence receptor subunit 3","Uniprot":["Q9UNL2"],"Chromosome":"3","Position":"156539553-156555149","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"1024.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014906"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014906":"AB_2195736"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.43e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.46e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.84e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"}},{"Gene":"SSR4","Gene synonym":["TRAPD"],"Ensembl":"ENSG00000180879","Gene description":"Signal sequence receptor subunit 4","Uniprot":["P51571"],"Chromosome":"X","Position":"153793516-153798499","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"3119.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"1769.3","Plasma cells":"5331.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045209"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA045209":"AB_10961407"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.76e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.51e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"}},{"Gene":"SSTR1","Gene synonym":[],"Ensembl":"ENSG00000139874","Gene description":"Somatostatin receptor 1","Uniprot":["P30872"],"Chromosome":"14","Position":"38207904-38213067","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.0","intestine":"13.8","stomach 1":"21.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"8.5","Enteroendocrine cells":"25.5","Gastric mucus-secreting cells":"18.5","Oligodendrocyte precursor cells":"23.1","Paneth cells":"11.3","Proximal enterocytes":"11.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"5.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"8.9"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003207","HPA031506"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA003207":null,"HPA031506":"AB_2673913"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.28e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"}},{"Gene":"SSTR2","Gene synonym":[],"Ensembl":"ENSG00000180616","Gene description":"Somatostatin receptor 2","Uniprot":["P30874"],"Chromosome":"17","Position":"73165010-73176633","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"9.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"38.0","Enteroendocrine cells":"47.7","Horizontal cells":"77.5","Mucus glandular cells":"27.1","Smooth muscle cells":"45.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"23.3"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Pancreas - Alpha cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007264"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007264":"AB_1080053"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.04e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"}},{"Gene":"SSTR3","Gene synonym":[],"Ensembl":"ENSG00000278195","Gene description":"Somatostatin receptor 3","Uniprot":["P32745"],"Chromosome":"22","Position":"37204237-37212477","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"7.6","lymphoid tissue":"11.1","testis":"7.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Sertoli cells":"11.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"1.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"1.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"T-cells":"1.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"31","RNA cell line specific nTPM":{"lymphoma":"7.4","Myeloma":"19.6"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Plasma cells","Kidney - Podocytes","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022647"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022647":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"}},{"Gene":"SSTR4","Gene synonym":[],"Ensembl":"ENSG00000132671","Gene description":"Somatostatin receptor 4","Uniprot":["P31391"],"Chromosome":"20","Position":"23035312-23039237","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"1.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064252"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064252":"AB_2685227"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SSTR5","Gene synonym":[],"Ensembl":"ENSG00000162009","Gene description":"Somatostatin receptor 5","Uniprot":["P35346"],"Chromosome":"16","Position":"1078781-1080142","Protein class":["FDA approved drug targets","G-protein coupled receptors","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"6.9","kidney":"2.9","pituitary gland":"7.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hypothalamus":"1.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"8.2"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"4.1","hypothalamus":"2.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066503"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":null,"Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA066503":"AB_2685679"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"}},{"Gene":"SSX5","Gene synonym":[],"Ensembl":"ENSG00000165583","Gene description":"SSX family member 5","Uniprot":["O60225"],"Chromosome":"X","Position":"48186220-48196795","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"33","RNA single cell type specific nTPM":{"Spermatocytes":"2.2","Spermatogonia":"4.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045683","HPA071685"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 47: Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA045683":"AB_2679418","HPA071685":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"ST14","Gene synonym":["HAI","MT-SP1","PRSS14","SNC19","TMPRSS14"],"Ensembl":"ENSG00000149418","Gene description":"ST14 transmembrane serine protease matriptase","Uniprot":["Q9Y5Y6"],"Chromosome":"11","Position":"130159782-130210362","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes","Disease variant","Hypotrichosis","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"144.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"328.1","Intestinal goblet cells":"182.4","Paneth cells":"166.7","Proximal enterocytes":"205.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"10.0"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"plasmacytoid DC":"25.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"25.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Colon - Colon enterocytes","Heart muscle - Macrophages","Pancreas - Ductal cells","Skeletal muscle - Macrophages","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047014","HPA056258"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA047014":"AB_2679902","HPA056258":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.03e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"}},{"Gene":"ST3GAL2","Gene synonym":["SIAT4B","ST3GalA.2","ST3GALII"],"Ensembl":"ENSG00000157350","Gene description":"ST3 beta-galactoside alpha-2,3-sialyltransferase 2","Uniprot":["Q16842"],"Chromosome":"16","Position":"70375977-70439237","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"83.5","Langerhans cells":"48.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017270"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA017270":"AB_1857523"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.79e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.34e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"}},{"Gene":"ST3GAL3","Gene synonym":["MRT12","SIAT6"],"Ensembl":"ENSG00000126091","Gene description":"ST3 beta-galactoside alpha-2,3-sialyltransferase 3","Uniprot":["Q11203"],"Chromosome":"1","Position":"43705824-43931165","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"88.0","tongue":"82.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"57.9","Excitatory neurons":"93.1","Inhibitory neurons":"117.4","Microglial cells":"55.6","Oligodendrocyte precursor cells":"64.0","Oligodendrocytes":"62.5","Rod photoreceptor cells":"76.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051102"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051102":"AB_2681344"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"}},{"Gene":"ST3GAL4","Gene synonym":["CGS23","FLJ11867","NANTA3","SAT3","SIAT4","SIAT4C","STZ"],"Ensembl":"ENSG00000110080","Gene description":"ST3 beta-galactoside alpha-2,3-sialyltransferase 4","Uniprot":["Q11206"],"Chromosome":"11","Position":"126355640-126440344","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Granulosa cells":"272.5","Syncytiotrophoblasts":"1045.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"57.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"111.9","neutrophil":"71.8","plasmacytoid DC":"93.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"93.7","granulocytes":"111.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"skin cancer":"240.8"},"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049827"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049827":"AB_2680900"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-3"}},{"Gene":"ST3GAL5","Gene synonym":["SIAT9","SIATGM3S","ST3GalV"],"Ensembl":"ENSG00000115525","Gene description":"ST3 beta-galactoside alpha-2,3-sialyltransferase 5","Uniprot":["Q9UNP4"],"Chromosome":"2","Position":"85837120-85905199","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"47.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"125.0","Oligodendrocytes":"102.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"41.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"27.5"},"RNA tissue cell type enrichment":["Breast - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034708","HPA040425","HPA068928"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA034708":"AB_10601594","HPA040425":"AB_2676978","HPA068928":"AB_2686060"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.25e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.99e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.48e-4"}},{"Gene":"ST3GAL6","Gene synonym":["SIAT10","ST3GALVI"],"Ensembl":"ENSG00000064225","Gene description":"ST3 beta-galactoside alpha-2,3-sialyltransferase 6","Uniprot":["Q9Y274"],"Chromosome":"3","Position":"98732236-98821201","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"56.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"128.9","Extravillous trophoblasts":"79.5","Langerhans cells":"84.8","Microglial cells":"130.4","Oligodendrocyte precursor cells":"164.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"melanoma":"17.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"49.6","neutrophil":"57.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"143","RNA blood lineage specific nTPM":{"dendritic cells":"24.2","granulocytes":"57.6","monocytes":"17.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Myeloma":"56.6","Neuroblastoma":"21.9","skin cancer":"49.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018792"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5800000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018792":"AB_10964349"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-4"}},{"Gene":"ST6GAL1","Gene synonym":["SIAT1"],"Ensembl":"ENSG00000073849","Gene description":"ST6 beta-galactoside alpha-2,6-sialyltransferase 1","Uniprot":["P15907"],"Chromosome":"3","Position":"186930325-187078553","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"495.9","lymphoid tissue":"148.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"516.1","Kupffer cells":"213.3","Microglial cells":"586.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"70.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"104.1","Myeloma":"146.5"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skin - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015018","CAB016122"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":15000000,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015018":"AB_629203","CAB016122":"AB_627178"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"}},{"Gene":"ST6GAL2","Gene synonym":["KIAA1877","SIAT2","St6GalII"],"Ensembl":"ENSG00000144057","Gene description":"ST6 beta-galactoside alpha-2,6-sialyltransferase 2","Uniprot":["Q96JF0"],"Chromosome":"2","Position":"106801600-106887108","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"11.0","thyroid gland":"28.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"56.9","Excitatory neurons":"77.4","Granulosa cells":"108.9","Inhibitory neurons":"43.6","Oligodendrocyte precursor cells":"90.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"thyroid cancer":"16.0"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"77","RNA brain regional specific nTPM":{"amygdala":"6.9","basal ganglia":"7.4","cerebral cortex":"11.0","hippocampal formation":"10.8","thalamus":"4.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"12.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Heart muscle - Smooth muscle cells","Liver - Hepatic stellate cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014459"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA014459":"AB_1857528"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"}},{"Gene":"ST6GALNAC1","Gene synonym":["SIAT7A","ST6GalNAcI"],"Ensembl":"ENSG00000070526","Gene description":"ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1","Uniprot":["Q9NSC7"],"Chromosome":"17","Position":"76624761-76643786","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"cervix":"61.1","intestine":"195.9","stomach 1":"64.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Intestinal goblet cells":"631.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"41.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory CD4 T-cell":"8.9","naive CD4 T-cell":"3.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"T-cells":"8.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Respiratory ciliated cells","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014767","HPA014975"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3500000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA014767":null,"HPA014975":"AB_1857529"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.54e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"}},{"Gene":"ST6GALNAC4","Gene synonym":["SIAT3C","SIAT7D","ST6GALNACIV"],"Ensembl":"ENSG00000136840","Gene description":"ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4","Uniprot":["Q9H4F1"],"Chromosome":"9","Position":"127907886-127917041","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"72.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"74.8","dendritic cells":"98.4","Erythroid cells":"91.1","Plasma cells":"98.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"plasmacytoid DC":"233.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"dendritic cells":"233.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009042"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA009042":"AB_1079963"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.63e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.12e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"}},{"Gene":"ST6GALNAC6","Gene synonym":["SIAT7F","ST6GALNACVI"],"Ensembl":"ENSG00000160408","Gene description":"ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6","Uniprot":["Q969X2"],"Chromosome":"9","Position":"127885321-127905408","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"12.7","Excitatory neurons":"11.4","Inhibitory neurons":"10.4","NK-cells":"10.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"NK-cells":"23.7","T-cells":"25.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018890"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018890":"AB_1857531"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"}},{"Gene":"ST7","Gene synonym":["ETS7q","FAM4A","FAM4A1","HELG","RAY1","SEN4","TSG7"],"Ensembl":"ENSG00000004866","Gene description":"Suppression of tumorigenicity 7","Uniprot":["Q9NRC1"],"Chromosome":"7","Position":"116953238-117230176","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"178.4","Early spermatids":"108.6","Excitatory neurons":"188.7","Inhibitory neurons":"171.9","Oligodendrocyte precursor cells":"106.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038325","HPA038326"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA038325":"AB_10671740","HPA038326":"AB_10672644"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.39e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"}},{"Gene":"ST7L","Gene synonym":["FAM4B","FLJ20284","ST7R","STLR"],"Ensembl":"ENSG00000007341","Gene description":"Suppression of tumorigenicity 7 like","Uniprot":["Q8TDW4"],"Chromosome":"1","Position":"112523514-112620825","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"36.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"177.3","Late spermatids":"310.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042324","HPA075418"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA042324":"AB_10794273","HPA075418":"AB_2686749"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.34e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.96e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.16e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.04e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"}},{"Gene":"ST8SIA1","Gene synonym":["SIAT8","SIAT8A"],"Ensembl":"ENSG00000111728","Gene description":"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1","Uniprot":["Q92185"],"Chromosome":"12","Position":"22063773-22437041","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"15.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"131.2","Inhibitory neurons":"149.0","Oligodendrocyte precursor cells":"189.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"4.0","skin cancer":"11.1"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026775"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026775":"AB_1857534"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"}},{"Gene":"ST8SIA3","Gene synonym":["SIAT8C"],"Ensembl":"ENSG00000177511","Gene description":"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3","Uniprot":["O43173"],"Chromosome":"18","Position":"57352557-57371731","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"21.7","pituitary gland":"8.1","retina":"7.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"24.6","Excitatory neurons":"73.8","Horizontal cells":"41.7","Inhibitory neurons":"55.2","Oligodendrocyte precursor cells":"21.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"glioma":"0.9","pancreatic cancer":"1.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"8.8","thyroid cancer":"4.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063398","HPA066783"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA063398":"AB_2685004","HPA066783":"AB_2685721"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ST8SIA5","Gene synonym":["SIAT8E"],"Ensembl":"ENSG00000101638","Gene description":"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5","Uniprot":["O15466"],"Chromosome":"18","Position":"46667821-46759257","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"12.2","brain":"17.0","parathyroid gland":"6.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"104.6","Inhibitory neurons":"73.7","Oligodendrocyte precursor cells":"30.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"9.5"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043813","HPA046771"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Midbody"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Midbody"],"Subcellular additional location":null,"Antibody RRID":{"HPA043813":"AB_2678683","HPA046771":"AB_2679798"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"}},{"Gene":"STAB1","Gene synonym":["CLEVER-1","FEEL-1","FELE-1","FEX1","KIAA0246","SCARH2","STAB-1"],"Ensembl":"ENSG00000010327","Gene description":"Stabilin 1","Uniprot":["Q9NY15"],"Chromosome":"3","Position":"52495338-52524495","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Inflammatory response"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"439.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Endothelial cells":"127.8","Fibroblasts":"127.2","Hofbauer cells":"147.9","Kupffer cells":"242.8","Macrophages":"205.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"59","RNA blood cell specific nTPM":{"classical monocyte":"9.4","intermediate monocyte":"5.7","myeloid DC":"2.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"60","RNA blood lineage specific nTPM":{"dendritic cells":"2.5","monocytes":"9.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"64","RNA cell line specific nTPM":{"Leukemia":"14.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005434"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"96000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA005434":"AB_1080097"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.59e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.88e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"}},{"Gene":"STAB2","Gene synonym":["DKFZP434E0321","FEEL-2","FELL","HARE","SCARH1","STAB-2"],"Ensembl":"ENSG00000136011","Gene description":"Stabilin 2","Uniprot":["Q8WWQ8"],"Chromosome":"12","Position":"103587273-103766719","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"65.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Endothelial cells":"38.6","Fibroblasts":"19.8","Kupffer cells":"29.0","Late spermatids":"11.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Liver - Sinusoid Endothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026871","HPA072699"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA026871":"AB_1857536","HPA072699":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"}},{"Gene":"STARD3","Gene synonym":["es64","MLN64"],"Ensembl":"ENSG00000131748","Gene description":"StAR related lipid transfer domain containing 3","Uniprot":["Q14849"],"Chromosome":"17","Position":"39637090-39664201","Protein class":["Cancer-related genes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"164.1"},"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017021","HPA024307","HPA073948"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"CAB017021":null,"HPA024307":null,"HPA073948":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.60e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"}},{"Gene":"STARD3NL","Gene synonym":["MENTHO","MGC3251"],"Ensembl":"ENSG00000010270","Gene description":"STARD3 N-terminal like","Uniprot":["O95772"],"Chromosome":"7","Position":"38178245-38230670","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"134.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019204"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA019204":"AB_2197800"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.44e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.48e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"}},{"Gene":"STARD9","Gene synonym":["KIAA1300","KIF16A"],"Ensembl":"ENSG00000159433","Gene description":"StAR related lipid transfer domain containing 9","Uniprot":["Q9P2P6"],"Chromosome":"15","Position":"42575606-42720998","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"43.6","Excitatory neurons":"38.8","Oligodendrocytes":"76.4","Rod photoreceptor cells":"62.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014562"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014562":"AB_10603033"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"}},{"Gene":"STAT3","Gene synonym":["APRF"],"Ensembl":"ENSG00000168610","Gene description":"Signal transducer and activator of transcription 3","Uniprot":["P40763"],"Chromosome":"17","Position":"42313324-42388540","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"511.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Neutrophils"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001671","CAB003859","HPA058603","CAB068241","CAB068242"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB003859":"AB_347629","CAB068241":"AB_2665663","CAB068242":"AB_2665662","HPA001671":"AB_1080102","HPA058603":"AB_2683772"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"}},{"Gene":"STAT6","Gene synonym":["D12S1644","IL-4-STAT"],"Ensembl":"ENSG00000166888","Gene description":"Signal transducer and activator of transcription 6","Uniprot":["P42226"],"Chromosome":"12","Position":"57095408-57132139","Protein class":["Cancer-related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001861"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA001861":"AB_1080106"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.69e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.76e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-4"}},{"Gene":"STEAP1","Gene synonym":["PRSS24","STEAP"],"Ensembl":"ENSG00000164647","Gene description":"STEAP family member 1","Uniprot":["Q9UHE8"],"Chromosome":"7","Position":"90154456-90164829","Protein class":["Cancer-related genes","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Ion transport","Iron transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"83.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"150.5","Club cells":"63.7","Ionocytes":"148.4","Prostatic glandular cells":"183.2","Thymic epithelial cells":"88.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"prostate cancer":"94.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"153.4"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Prostate - Prostate glandular cells","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030985"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030985":"AB_2673686"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"}},{"Gene":"STEAP1B","Gene synonym":[],"Ensembl":"ENSG00000105889","Gene description":"STEAP family member 1B","Uniprot":["Q6NZ63"],"Chromosome":"7","Position":"22419444-22727613","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.9","choroid plexus":"4.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"122.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"5.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"67","RNA blood cell specific nTPM":{"memory B-cell":"8.4","naive B-cell":"4.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"84","RNA blood lineage specific nTPM":{"B-cells":"8.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"30.4"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"}},{"Gene":"STEAP2","Gene synonym":["IPCA-1","PCANAP1","STAMP1","STMP"],"Ensembl":"ENSG00000157214","Gene description":"STEAP2 metalloreductase","Uniprot":["Q8NFT2"],"Chromosome":"7","Position":"90167590-90238137","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Ion transport","Iron transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"prostate":"127.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Prostatic glandular cells":"651.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"prostate cancer":"88.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"80.0"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029115","HPA055603"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029115":"AB_10603894","HPA055603":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"}},{"Gene":"STEAP3","Gene synonym":["dudlin-2","STMP3","TSAP6"],"Ensembl":"ENSG00000115107","Gene description":"STEAP3 metalloreductase","Uniprot":["Q658P3"],"Chromosome":"2","Position":"119223831-119265652","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Cell cycle","Ion transport","Iron transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"189.5","parathyroid gland":"78.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"76.0","Respiratory ciliated cells":"40.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"2.4","intermediate monocyte":"2.7","myeloid DC":"4.1","NK-cell":"1.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"4.1","monocytes":"2.7","NK-cells":"1.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Macrophages","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050510"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA050510":"AB_2681151"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"}},{"Gene":"STEAP4","Gene synonym":["FLJ23153","SchLAH","STAMP2","TIARP","TNFAIP9"],"Ensembl":"ENSG00000127954","Gene description":"STEAP4 metalloreductase","Uniprot":["Q687X5"],"Chromosome":"7","Position":"88270892-88306894","Protein class":["Enzymes","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Ion transport","Iron transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"113.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"153.0","Club cells":"156.9","Ionocytes":"99.1","Leydig cells":"116.3","Mucus glandular cells":"121.8","Sertoli cells":"207.3","Smooth muscle cells":"299.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"45.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"neutrophil":"163.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"granulocytes":"163.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"66.9"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065201"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA065201":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.97e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.77e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"}},{"Gene":"STIM1","Gene synonym":["D11S4896E","GOK"],"Ensembl":"ENSG00000167323","Gene description":"Stromal interaction molecule 1","Uniprot":["Q13586"],"Chromosome":"11","Position":"3854527-4093210","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011088","HPA012123","CAB037128","CAB037288"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1900000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB037128":"AB_1079007","CAB037288":"AB_1079008","HPA011088":"AB_1849884","HPA012123":"AB_1849882"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"}},{"Gene":"STIM2","Gene synonym":[],"Ensembl":"ENSG00000109689","Gene description":"Stromal interaction molecule 2","Uniprot":["Q9P246"],"Chromosome":"4","Position":"26857601-27025381","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"84.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036933","CAB037196","HPA057511"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB037196":"AB_1841195","HPA036933":"AB_2675391","HPA057511":"AB_2683453"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.97e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"}},{"Gene":"STIMATE","Gene synonym":["MGC52022","TMEM110"],"Ensembl":"ENSG00000213533","Gene description":"STIM activating enhancer","Uniprot":["Q86TL2"],"Chromosome":"3","Position":"52836219-52897548","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"24.4","Hepatocytes":"20.5","Late spermatids":"16.7","Proximal tubular cells":"12.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051855"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA051855":"AB_2681639"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"}},{"Gene":"STIMATE-MUSTN1","Gene synonym":["TMEM110-MUSTN1"],"Ensembl":"ENSG00000248592","Gene description":"STIMATE-MUSTN1 readthrough","Uniprot":[],"Chromosome":"3","Position":"52833121-52897562","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"14.9","skeletal muscle":"9.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"1.1","Cone photoreceptor cells":"1.7","Gastric mucus-secreting cells":"1.8","Plasma cells":"1.5","Smooth muscle cells":"4.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051855"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 69: BICR 18 - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA051855":"AB_2681639"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-5"}},{"Gene":"STING1","Gene synonym":["ERIS","FLJ38577","MITA","MPYS","NET23","STING","TMEM173"],"Ensembl":"ENSG00000184584","Gene description":"Stimulator of interferon response cGAMP interactor 1","Uniprot":["Q86WV6"],"Chromosome":"5","Position":"139475533-139482935","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Autophagy","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endothelial cells":"97.2","Respiratory ciliated cells":"129.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Breast - Smooth muscle cells","Colon - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038116","HPA038534"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA038116":"AB_2675841","HPA038534":"AB_2676067"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.59e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"STK11","Gene synonym":["LKB1","PJS"],"Ensembl":"ENSG00000118046","Gene description":"Serine\/threonine kinase 11","Uniprot":["Q15831"],"Chromosome":"19","Position":"1177558-1228431","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Autophagy","Cell cycle","Differentiation","DNA damage","Spermatogenesis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"152.3","Late spermatids":"360.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"9.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016231","HPA017254","CAB022105","HPA067481"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016231":"AB_627890","CAB022105":null,"HPA017254":"AB_1852924","HPA067481":"AB_2685847"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.69e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.96e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-3"}},{"Gene":"STK11IP","Gene synonym":["KIAA1898","LIP1","LKB1IP","STK11IP1"],"Ensembl":"ENSG00000144589","Gene description":"Serine\/threonine kinase 11 interacting protein","Uniprot":["Q8N1F8"],"Chromosome":"2","Position":"219597857-219616451","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"15.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036837","HPA036838","HPA053192"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036837":"AB_10969754","HPA036838":"AB_10672100","HPA053192":"AB_2682075"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"}},{"Gene":"STK17A","Gene synonym":["DRAK1"],"Ensembl":"ENSG00000164543","Gene description":"Serine\/threonine kinase 17a","Uniprot":["Q9UEE5"],"Chromosome":"7","Position":"43582758-43650713","Protein class":["Enzymes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"227.0","B-cells":"255.8","NK-cells":"282.7","T-cells":"276.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018138","HPA037979"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Plasma membrane"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA018138":"AB_2669784","HPA037979":"AB_10795247"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"}},{"Gene":"STK17B","Gene synonym":["DRAK2"],"Ensembl":"ENSG00000081320","Gene description":"Serine\/threonine kinase 17b","Uniprot":["O94768"],"Chromosome":"2","Position":"196133583-196176503","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"376.2","lymphoid tissue":"113.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"245.3","dendritic cells":"222.3","granulocytes":"239.5","monocytes":"506.2","NK-cells":"294.1","Schwann cells":"292.7","T-cells":"369.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"60.1"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebellum":"63.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034858"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA034858":"AB_10670981"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.72e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"}},{"Gene":"STK26","Gene synonym":["MASK","MST4"],"Ensembl":"ENSG00000134602","Gene description":"Serine\/threonine kinase 26","Uniprot":["Q9P289"],"Chromosome":"X","Position":"132023302-132075943","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"70.0","epididymis":"56.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"55.1","NK-cells":"56.3","Syncytiotrophoblasts":"55.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast myoepithelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059921"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Golgi apparatus","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"360000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Centrosome","Cytosol"],"Antibody RRID":{"HPA059921":"AB_2684163"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.82e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.87e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"}},{"Gene":"STK33","Gene synonym":[],"Ensembl":"ENSG00000130413","Gene description":"Serine\/threonine kinase 33","Uniprot":["Q9BYT3"],"Chromosome":"11","Position":"8391868-8594289","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"49.3","testis":"51.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"207.2","Early spermatids":"109.1","Endometrial ciliated cells":"224.8","Late spermatids":"154.9","Oligodendrocyte precursor cells":"112.6","Respiratory ciliated cells":"99.4","Rod photoreceptor cells":"85.7","Spermatocytes":"134.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"4.1","naive B-cell":"2.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"4.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Cardiomyocytes","Lung - Respiratory ciliated cells","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015742","HPA056855"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA015742":"AB_1857592","HPA056855":"AB_2683257"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.89e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"}},{"Gene":"STK36","Gene synonym":["FU","KIAA1278"],"Ensembl":"ENSG00000163482","Gene description":"Serine\/threonine kinase 36","Uniprot":["Q9NRP7"],"Chromosome":"2","Position":"218672069-218702716","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Ciliopathy","Primary ciliary dyskinesia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Respiratory ciliated cells":"44.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027409","HPA027453","HPA030058"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027409":"AB_10600223","HPA027453":"AB_10601893","HPA030058":"AB_10601225"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.20e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"}},{"Gene":"STK40","Gene synonym":["MGC4796","SgK495"],"Ensembl":"ENSG00000196182","Gene description":"Serine\/threonine kinase 40","Uniprot":["Q8N2I9"],"Chromosome":"1","Position":"36339624-36385924","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"113.1","Late spermatids":"232.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"25.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"25.2","monocytes":"12.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008026"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA008026":"AB_1857603"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.59e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"}},{"Gene":"STKLD1","Gene synonym":["C9orf96","MGC43306","SGK071"],"Ensembl":"ENSG00000198870","Gene description":"Serine\/threonine kinase like domain containing 1","Uniprot":["Q8NE28"],"Chromosome":"9","Position":"133376366-133406096","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"testis":"9.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"31.9","Late spermatids":"65.7","Spermatocytes":"17.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029902"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029902":"AB_10603554"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"}},{"Gene":"STOM","Gene synonym":["BND7","EPB7","EPB72"],"Ensembl":"ENSG00000148175","Gene description":"Stomatin","Uniprot":["P27105"],"Chromosome":"9","Position":"121338987-121370304","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"437.6","Alveolar cells type 1":"397.5","Endothelial cells":"353.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Neutrophils","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Lung - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010961","HPA011419"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA010961":"AB_1080111","HPA011419":"AB_1080109"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"}},{"Gene":"STOML1","Gene synonym":["FLJ36370","hUNC-24","SLP-1","STORP"],"Ensembl":"ENSG00000067221","Gene description":"Stomatin like 1","Uniprot":["Q9UBI4"],"Chromosome":"15","Position":"73978926-73994622","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042353"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042353":"AB_10797387"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"}},{"Gene":"STOML3","Gene synonym":["Epb7.2l","SRO"],"Ensembl":"ENSG00000133115","Gene description":"Stomatin like 3","Uniprot":["Q8TAV4"],"Chromosome":"13","Position":"38965925-38990859","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"fallopian tube":"34.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"80.6","Respiratory ciliated cells":"69.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"endometrial cancer":"2.4","lung cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"olfactory bulb":"23.6"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012892","HPA071011"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA012892":"AB_1857610","HPA071011":"AB_2732169"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.49e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"}},{"Gene":"STRA6","Gene synonym":["FLJ12541"],"Ensembl":"ENSG00000137868","Gene description":"Signaling receptor and transporter of retinol STRA6","Uniprot":["Q9BX79"],"Chromosome":"15","Position":"74179466-74212267","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"24.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"22.0","Endometrial stromal cells":"42.5","Extravillous trophoblasts":"11.8","Ionocytes":"10.1","Syncytiotrophoblasts":"27.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"27.5"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Lung - Respiratory ciliated cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040839"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040839":"AB_10794881"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"}},{"Gene":"STRIT1","Gene synonym":["DWORF"],"Ensembl":"ENSG00000240045","Gene description":"Small transmembrane regulator of ion transport 1","Uniprot":["P0DN84"],"Chromosome":"3","Position":"155290227-155293683","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"79","RNA tissue specific nTPM":{"skeletal muscle":"1711.3","tongue":"698.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"51","RNA single cell type specific nTPM":{"Skeletal myocytes":"347.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"1.1","prostate cancer":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"1.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-4"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"STT3A","Gene synonym":["ITM1","MGC9042","STT3-A","TMC"],"Ensembl":"ENSG00000134910","Gene description":"STT3 oligosaccharyltransferase complex catalytic subunit A","Uniprot":["P46977"],"Chromosome":"11","Position":"125591712-125625215","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"391.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"118.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030735"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030735":"AB_10603342"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.57e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"}},{"Gene":"STT3B","Gene synonym":["FLJ90106","SIMP","STT3-B"],"Ensembl":"ENSG00000163527","Gene description":"STT3 oligosaccharyltransferase complex catalytic subunit B","Uniprot":["Q8TCJ2"],"Chromosome":"3","Position":"31532638-31637616","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"266.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036448","HPA036646"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA036448":"AB_2675129","HPA036646":"AB_10673472"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.91e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"STUM","Gene synonym":["C1orf95","DKFZp761P211"],"Ensembl":"ENSG00000203685","Gene description":"Stum, mechanosensory transduction mediator homolog","Uniprot":["Q69YW2"],"Chromosome":"1","Position":"226548764-226609230","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"brain":"234.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"19.6","Enteroendocrine cells":"7.8","Excitatory neurons":"18.8","Inhibitory neurons":"6.6","Oligodendrocyte precursor cells":"12.5","Sertoli cells":"8.3","Smooth muscle cells":"8.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"medulla oblongata":"234.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"2.4","lung cancer":"1.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"amygdala":"70.3","basal ganglia":"76.6","cerebral cortex":"75.5","hippocampal formation":"74.0","thalamus":"21.3"},"Antibody":["HPA074381"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA074381":"AB_2732253"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.40e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"}},{"Gene":"STX10","Gene synonym":["hsyn10","SYN10"],"Ensembl":"ENSG00000104915","Gene description":"Syntaxin 10","Uniprot":["O60499"],"Chromosome":"19","Position":"13144058-13150383","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035303","HPA056439"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035303":"AB_10671932","HPA056439":"AB_2683135"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.26e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.69e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"}},{"Gene":"STX12","Gene synonym":["STX13","STX14"],"Ensembl":"ENSG00000117758","Gene description":"Syntaxin 12","Uniprot":["Q86Y82"],"Chromosome":"1","Position":"27773219-27824443","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041038","HPA055300"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041038":"AB_10794261","HPA055300":"AB_2682778"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"}},{"Gene":"STX16","Gene synonym":["hsyn16","SYN16"],"Ensembl":"ENSG00000124222","Gene description":"Syntaxin 16","Uniprot":["O14662"],"Chromosome":"20","Position":"58651253-58679526","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041019","HPA042033"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA041019":"AB_10964273","HPA042033":"AB_10963935"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.18e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"}},{"Gene":"STX17","Gene synonym":["FLJ20651"],"Ensembl":"ENSG00000136874","Gene description":"Syntaxin 17","Uniprot":["P56962"],"Chromosome":"9","Position":"99906654-99974534","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy","ER-Golgi transport","Host-virus interaction","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001204"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001204":"AB_1080118"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.62e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"}},{"Gene":"STX18","Gene synonym":["Ufe1"],"Ensembl":"ENSG00000168818","Gene description":"Syntaxin 18","Uniprot":["Q9P2W9"],"Chromosome":"4","Position":"4415742-4542346","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"119.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"169.0","Glandular and luminal cells":"255.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"endometrial cancer":"43.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003019"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Endoplasmic reticulum","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA003019":"AB_1857622"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.84e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.33e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.03e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.69e-4"}},{"Gene":"STX1A","Gene synonym":["HPC-1","p35-1","STX1"],"Ensembl":"ENSG00000106089","Gene description":"Syntaxin 1A","Uniprot":["Q16623"],"Chromosome":"7","Position":"73699206-73719672","Protein class":["Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Exocytosis","Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":["Williams-Beuren syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"128.5","pituitary gland":"98.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"30.0","Excitatory neurons":"59.8","Pancreatic endocrine cells":"34.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"amygdala":"246.2","basal ganglia":"93.9","cerebral cortex":"354.4","hippocampal formation":"229.1","white matter":"116.1"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"amygdala":"37.6","cerebral cortex":"103.4","hippocampal formation":"87.2"},"Antibody":["CAB008372","HPA069176"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 26: NCI-H716 - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"CAB008372":"AB_592786","HPA069176":"AB_2686098"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.63e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"}},{"Gene":"STX1B","Gene synonym":["STX1B1","STX1B2"],"Ensembl":"ENSG00000099365","Gene description":"Syntaxin 1B","Uniprot":["P61266"],"Chromosome":"16","Position":"30989256-31010638","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"137.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"36.3","Horizontal cells":"53.2","Inhibitory neurons":"30.4","Late spermatids":"14.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"5.1"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"137.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"10.8"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069176","CAB079008"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"CAB079008":null,"HPA069176":"AB_2686098"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"}},{"Gene":"STX2","Gene synonym":["EPIM","EPM","STX2A","STX2B","STX2C"],"Ensembl":"ENSG00000111450","Gene description":"Syntaxin 2","Uniprot":["P32856"],"Chromosome":"12","Position":"130789600-130839266","Protein class":["Cancer-related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"133.4","Endometrial ciliated cells":"93.6","Late spermatids":"126.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Skin - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069176","CAB079007"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"CAB079007":null,"HPA069176":"AB_2686098"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"}},{"Gene":"STX3","Gene synonym":["STX3A"],"Ensembl":"ENSG00000166900","Gene description":"Syntaxin 3","Uniprot":["Q13277"],"Chromosome":"11","Position":"59713456-59805882","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"313.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"326.4","Cone photoreceptor cells":"355.0","Rod photoreceptor cells":"360.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"42.5","eosinophil":"74.1","neutrophil":"60.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"74.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002191","HPA069176"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"HPA002191":"AB_1080165","HPA069176":"AB_2686098"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.41e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"}},{"Gene":"STX4","Gene synonym":["p35-2","STX4A"],"Ensembl":"ENSG00000103496","Gene description":"Syntaxin 4","Uniprot":["Q12846"],"Chromosome":"16","Position":"31032889-31042975","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"171.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001330"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA001330":"AB_1080167"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.65e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.88e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"}},{"Gene":"STX5","Gene synonym":["SED5","STX5A"],"Ensembl":"ENSG00000162236","Gene description":"Syntaxin 5","Uniprot":["Q13190"],"Chromosome":"11","Position":"62806860-62832051","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"162.2","Syncytiotrophoblasts":"188.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001358"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA001358":"AB_1080119"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"}},{"Gene":"STX6","Gene synonym":[],"Ensembl":"ENSG00000135823","Gene description":"Syntaxin 6","Uniprot":["O43752"],"Chromosome":"1","Position":"180972712-181023121","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038557","HPA038558"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA038557":"AB_2676082","HPA038558":"AB_10672716"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.24e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.93e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"}},{"Gene":"STX7","Gene synonym":[],"Ensembl":"ENSG00000079950","Gene description":"Syntaxin 7","Uniprot":["O15400"],"Chromosome":"6","Position":"132445867-132513198","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"53.6","classical monocyte":"51.6","eosinophil":"49.1","intermediate monocyte":"58.1","memory B-cell":"85.9","myeloid DC":"61.6","naive B-cell":"106.8","neutrophil":"83.2","non-classical monocyte":"61.6","plasmacytoid DC":"73.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001467","CAB062564"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Lysosomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"380000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Lysosomes"],"Subcellular additional location":null,"Antibody RRID":{"CAB062564":"AB_2665605","HPA001467":"AB_1857623"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"}},{"Gene":"STX8","Gene synonym":["CARB"],"Ensembl":"ENSG00000170310","Gene description":"Syntaxin 8","Uniprot":["Q9UNK0"],"Chromosome":"17","Position":"9250471-9576591","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"953.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001540"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA001540":"AB_1080168"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"}},{"Gene":"STXBP1","Gene synonym":["hUNC18","MUNC18-1","rbSec1","UNC18"],"Ensembl":"ENSG00000136854","Gene description":"Syntaxin binding protein 1","Uniprot":["P61764"],"Chromosome":"9","Position":"127579370-127696027","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"174.5","pituitary gland":"66.4","retina":"214.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"120.3","Cone photoreceptor cells":"187.8","Excitatory neurons":"239.8","Horizontal cells":"123.0","Inhibitory neurons":"153.7","Rod photoreceptor cells":"182.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"39.6"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"174.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Fibroblasts","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008209","HPA023483","CAB034434"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034434":"AB_2196699","HPA008209":"AB_1857624","HPA023483":"AB_1857625"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.78e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.47e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.73e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.81e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"}},{"Gene":"STXBP5","Gene synonym":["LLGL3","tomosyn"],"Ensembl":"ENSG00000164506","Gene description":"Syntaxin binding protein 5","Uniprot":["Q5T5C0"],"Chromosome":"6","Position":"147204425-147390476","Protein class":["Predicted intracellular proteins"],"Biological process":["Exocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"115.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"315.7","Excitatory neurons":"435.4","Inhibitory neurons":"293.5","Oligodendrocyte precursor cells":"197.4","Oligodendrocytes":"142.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"3.8","eosinophil":"9.2","neutrophil":"3.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"9.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039991","HPA049727","CAB079016"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB079016":null,"HPA039991":"AB_10673368","HPA049727":"AB_2680863"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.48e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.74e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"}},{"Gene":"STYK1","Gene synonym":["DKFZp761P1010","NOK","SuRTK106"],"Ensembl":"ENSG00000060140","Gene description":"Serine\/threonine\/tyrosine kinase 1","Uniprot":["Q6J9G0"],"Chromosome":"12","Position":"10618923-10674318","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"17.1","stomach 1":"17.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"19.1","Excitatory neurons":"20.3","Gastric mucus-secreting cells":"16.1","Intestinal goblet cells":"14.5","Prostatic glandular cells":"21.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"5.2"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"NK-cell":"12.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"NK-cells":"12.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Prostate - Prostate glandular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"2.3"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040468","HPA048569"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA040468":"AB_2676998","HPA048569":"AB_2680446"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"}},{"Gene":"SUCLA2","Gene synonym":["LINC00444"],"Ensembl":"ENSG00000136143","Gene description":"Succinate-CoA ligase ADP-forming subunit beta","Uniprot":["Q9P2R7"],"Chromosome":"13","Position":"47745736-48037968","Protein class":["Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Tricarboxylic acid cycle"],"Molecular function":["Ligase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"232.2","tongue":"271.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"207.4","Early spermatids":"225.4","Late spermatids":"315.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039435","HPA039536","HPA061528"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA039435":"AB_10673144","HPA039536":"AB_2676561","HPA061528":"AB_2684553"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.59e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.22e-4"}},{"Gene":"SUCNR1","Gene synonym":["GPR91"],"Ensembl":"ENSG00000198829","Gene description":"Succinate receptor 1","Uniprot":["Q9BXA5"],"Chromosome":"3","Position":"151873643-151884619","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"kidney":"39.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"9.3","Hofbauer cells":"18.6","Langerhans cells":"9.8","Macrophages":"14.5","Microglial cells":"8.2","Proximal tubular cells":"35.3","Smooth muscle cells":"8.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"11.3","Rhabdoid":"13.7"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022745"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022745":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"}},{"Gene":"SUCO","Gene synonym":["C1orf9","CH1","OPT","SLP1"],"Ensembl":"ENSG00000094975","Gene description":"SUN domain containing ossification factor","Uniprot":["Q9UBS9"],"Chromosome":"1","Position":"172532349-172611833","Protein class":["Predicted membrane proteins"],"Biological process":["Osteogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"83.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047251"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"45000","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Nucleoli fibrillar center","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA047251":"AB_2679999"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"}},{"Gene":"SUGCT","Gene synonym":["C7orf10","DERP13","FLJ11808","ORF19"],"Ensembl":"ENSG00000175600","Gene description":"Succinyl-CoA:glutarate-CoA transferase","Uniprot":["Q9HAC7"],"Chromosome":"7","Position":"40135005-40860763","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Glutaricaciduria"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"44.4","liver":"28.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"73.7","Early spermatids":"33.9","Inhibitory neurons":"37.7","Oligodendrocyte precursor cells":"55.8","Proximal tubular cells":"68.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026698","HPA026704","HPA026705"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026698":"AB_10600191","HPA026704":"AB_10600230","HPA026705":"AB_10601003"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-4"}},{"Gene":"SUMF2","Gene synonym":["DKFZp566I1024"],"Ensembl":"ENSG00000129103","Gene description":"Sulfatase modifying factor 2","Uniprot":["Q8NBJ7"],"Chromosome":"7","Position":"56064002-56080670","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024040","CAB025743","HPA074892"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"750000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB025743":null,"HPA024040":"AB_1857651","HPA074892":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.58e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.96e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.71e-4"}},{"Gene":"SUMO1","Gene synonym":["GMP1","OFC10","PIC1","SMT3C","SMT3H3","SUMO-1","UBL1"],"Ensembl":"ENSG00000116030","Gene description":"Small ubiquitin like modifier 1","Uniprot":["P63165"],"Chromosome":"2","Position":"202206182-202238599","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"cerebellum":"7.6"},"Antibody":["CAB004269","HPA056956"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Nucleoli","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":["Nucleoli","Nuclear bodies"],"Antibody RRID":{"CAB004269":"AB_628300","HPA056956":"AB_2683285"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.93e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"}},{"Gene":"SUMO3","Gene synonym":["SMT3A","SMT3H1"],"Ensembl":"ENSG00000184900","Gene description":"Small ubiquitin like modifier 3","Uniprot":["P55854"],"Chromosome":"21","Position":"44805617-44818779","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012180","HPA042123","HPA048064"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB012180":"AB_304041","HPA042123":"AB_2677860","HPA048064":"AB_2680244"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.88e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"}},{"Gene":"SUN1","Gene synonym":["FLJ12407","KIAA0810","UNC84A"],"Ensembl":"ENSG00000164828","Gene description":"Sad1 and UNC84 domain containing 1","Uniprot":["O94901"],"Chromosome":"7","Position":"816615-896435","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Meiosis","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"309.4","Late spermatids":"591.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008346","HPA008461"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA008346":"AB_1080462","HPA008461":"AB_1080461"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"}},{"Gene":"SUN2","Gene synonym":["UNC84B"],"Ensembl":"ENSG00000100242","Gene description":"Sad1 and UNC84 domain containing 2","Uniprot":["Q9UH99"],"Chromosome":"22","Position":"38734725-38794143","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Meiosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"181.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001209"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA001209":"AB_1080465"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"}},{"Gene":"SUN3","Gene synonym":["MGC33329","SUNC1"],"Ensembl":"ENSG00000164744","Gene description":"Sad1 and UNC84 domain containing 3","Uniprot":["Q8TAQ9"],"Chromosome":"7","Position":"47987148-48029119","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"126","RNA tissue specific nTPM":{"testis":"41.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"544.6","Late spermatids":"177.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"testis cancer":"2.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"4.6"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008344","HPA076890"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA008344":"AB_1857656","HPA076890":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-5"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"}},{"Gene":"SUN5","Gene synonym":["dJ726C3.1","SPAG4L","TSARG4"],"Ensembl":"ENSG00000167098","Gene description":"Sad1 and UNC84 domain containing 5","Uniprot":["Q8TC36"],"Chromosome":"20","Position":"32983773-33004433","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"449","RNA tissue specific nTPM":{"testis":"44.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"116","RNA single cell type specific nTPM":{"Early spermatids":"512.4","Late spermatids":"134.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048529"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048529":"AB_2680428"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"SURF1","Gene synonym":[],"Ensembl":"ENSG00000148290","Gene description":"SURF1 cytochrome c oxidase assembly factor","Uniprot":["Q15526"],"Chromosome":"9","Position":"133351758-133356676","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Leigh syndrome","Neurodegeneration","Neuropathy","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033946"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033946":"AB_2302648"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.92e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"}},{"Gene":"SURF4","Gene synonym":["ERV29","FLJ22993","MGC102753"],"Ensembl":"ENSG00000148248","Gene description":"Surfeit 4","Uniprot":["O15260"],"Chromosome":"9","Position":"133361450-133376166","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"278.0","Syncytiotrophoblasts":"355.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064613"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Endoplasmic reticulum","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"65000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nuclear membrane","Endoplasmic reticulum","Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA064613":"AB_2685299"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.85e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.47e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-3"}},{"Gene":"SUSD1","Gene synonym":["DKFZP761E1824"],"Ensembl":"ENSG00000106868","Gene description":"Sushi domain containing 1","Uniprot":["Q6UWL2"],"Chromosome":"9","Position":"112040783-112175297","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"27.8","Excitatory neurons":"24.8","Oligodendrocyte precursor cells":"36.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"11.0","plasmacytoid DC":"44.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"44.2","granulocytes":"11.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048554"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2300000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA048554":"AB_2680439"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.63e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"}},{"Gene":"SUSD2","Gene synonym":["BK65A6.2","FLJ22778","W5C5"],"Ensembl":"ENSG00000099994","Gene description":"Sushi domain containing 2","Uniprot":["Q9UGT4"],"Chromosome":"22","Position":"24181487-24189106","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"99.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 1":"191.4","Alveolar cells type 2":"137.1","Proximal enterocytes":"136.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"64.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"63.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatic stellate cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004117"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6800000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA004117":"AB_1857674"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"}},{"Gene":"SUSD3","Gene synonym":["MGC26847"],"Ensembl":"ENSG00000157303","Gene description":"Sushi domain containing 3","Uniprot":["Q96L08"],"Chromosome":"9","Position":"93058688-93085133","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"57.3","testis":"77.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"71.7","Hofbauer cells":"46.6","Proximal tubular cells":"42.1","Sertoli cells":"74.6","T-cells":"41.0","Theca cells":"65.9","Thymic epithelial cells":"62.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"50.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"breast cancer":"24.9","Leukemia":"29.5","lymphoma":"46.8","Myeloma":"21.6"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Kidney - Proximal tubular cells","Testis - Sertoli cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042310"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042310":"AB_10796902"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.13e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"}},{"Gene":"SUSD4","Gene synonym":["FLJ10052"],"Ensembl":"ENSG00000143502","Gene description":"Sushi domain containing 4","Uniprot":["Q5VX71"],"Chromosome":"1","Position":"223220819-223364233","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Complement pathway","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"69.0","esophagus":"51.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"82.4","Inhibitory neurons":"87.7","Oligodendrocyte precursor cells":"97.2","Squamous epithelial cells":"79.5","Suprabasal keratinocytes":"50.0","Theca cells":"54.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory CD4 T-cell":"6.8","naive CD4 T-cell":"10.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"40","RNA blood lineage specific nTPM":{"T-cells":"10.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"16.5"},"RNA tissue cell type enrichment":["Kidney - Ascending Loop of Henle cells","Lung - Respiratory ciliated cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058296"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA058296":"AB_2683672"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.28e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"}},{"Gene":"SUSD5","Gene synonym":["KIAA0527"],"Ensembl":"ENSG00000173705","Gene description":"Sushi domain containing 5","Uniprot":["O60279"],"Chromosome":"3","Position":"33150043-33218810","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"15.2","Inhibitory neurons":"10.3","Oligodendrocyte precursor cells":"58.7","Sertoli cells":"11.1","Smooth muscle cells":"34.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"5.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"14.1","Rhabdoid":"14.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Skeletal muscle - Smooth muscle cells","Skin - Fibroblast_2","Testis - Spermatogonia","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052788"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA052788":"AB_2681948"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"}},{"Gene":"SUSD6","Gene synonym":["KIAA0247"],"Ensembl":"ENSG00000100647","Gene description":"Sushi domain containing 6","Uniprot":["Q92537"],"Chromosome":"14","Position":"69611596-69715144","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"104.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030464"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"HPA030464":"AB_10601128"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"}},{"Gene":"SV2A","Gene synonym":["KIAA0736","SV2"],"Ensembl":"ENSG00000159164","Gene description":"Synaptic vesicle glycoprotein 2A","Uniprot":["Q7L0J3"],"Chromosome":"1","Position":"149903318-149917844","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"128.2","parathyroid gland":"48.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"87.0","Excitatory neurons":"62.5","Horizontal cells":"166.0","Inhibitory neurons":"104.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"27.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002226","HPA007863"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002226":"AB_564144","HPA007863":"AB_1080135"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.22e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-3"}},{"Gene":"SV2B","Gene synonym":["HsT19680","KIAA0735"],"Ensembl":"ENSG00000185518","Gene description":"Synaptic vesicle glycoprotein 2B","Uniprot":["Q7L1I2"],"Chromosome":"15","Position":"91099950-91302565","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"brain":"34.5","retina":"56.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Bipolar cells":"132.3","Cone photoreceptor cells":"148.2","Excitatory neurons":"448.6","Rod photoreceptor cells":"147.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"1.4"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046247"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046247":"AB_10963538"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-4"}},{"Gene":"SV2C","Gene synonym":[],"Ensembl":"ENSG00000122012","Gene description":"Synaptic vesicle glycoprotein 2C","Uniprot":["Q496J9"],"Chromosome":"5","Position":"76083383-76353939","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Neurotransmitter transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"brain":"55.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Excitatory neurons":"84.2","Horizontal cells":"37.8","Inhibitory neurons":"80.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"basophil":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"granulocytes":"1.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Neuroblastoma":"8.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040722","HPA040770"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA040722":"AB_10795624","HPA040770":"AB_10805828"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"}},{"Gene":"SVOP","Gene synonym":["DKFZp761H039"],"Ensembl":"ENSG00000166111","Gene description":"SV2 related protein","Uniprot":["Q8N4V2"],"Chromosome":"12","Position":"108907741-109021068","Protein class":["Predicted membrane proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"14.3","pituitary gland":"7.4","retina":"13.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"56.9","Early spermatids":"48.1","Excitatory neurons":"69.3","Inhibitory neurons":"74.0","Late spermatids":"131.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"glioma":"0.6","pancreatic cancer":"1.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"4.4"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Heart muscle - Cardiomyocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016573"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016573":"AB_2197027"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"}},{"Gene":"SVOPL","Gene synonym":["MGC46715"],"Ensembl":"ENSG00000157703","Gene description":"SVOP like","Uniprot":["Q8N434"],"Chromosome":"7","Position":"138594285-138701362","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"4.1","salivary gland":"4.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"granulocytes":"46.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"eosinophil":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"granulocytes":"2.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018035"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018035":"AB_2197028"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"}},{"Gene":"SYBU","Gene synonym":["FLJ20366","GOLSYN","KIAA1472","OCSYN","SNPHL"],"Ensembl":"ENSG00000147642","Gene description":"Syntabulin","Uniprot":["Q9NX95"],"Chromosome":"8","Position":"109573978-109691791","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"140.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"197.7","Inhibitory neurons":"126.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"21","RNA blood cell specific nTPM":{"memory B-cell":"6.4","naive B-cell":"3.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"27","RNA blood lineage specific nTPM":{"B-cells":"6.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053057"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA053057":"AB_2682028"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.74e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"}},{"Gene":"SYNDIG1","Gene synonym":["C20orf39","DSPC2","FLJ14220","IFITMD5","TMEM90B"],"Ensembl":"ENSG00000101463","Gene description":"Synapse differentiation inducing 1","Uniprot":["Q9H7V2"],"Chromosome":"20","Position":"24469629-24666616","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"36.4","heart muscle":"26.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"155.3","Microglial cells":"459.7","Oligodendrocytes":"202.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"10.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"7.0","Sarcoma":"7.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044271","HPA059267"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA044271":"AB_2732515","HPA059267":"AB_2683961"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.16e-6"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"}},{"Gene":"SYNDIG1L","Gene synonym":["capucin","DSPC1","IFITMD4","TMEM90A"],"Ensembl":"ENSG00000183379","Gene description":"Synapse differentiation inducing 1 like","Uniprot":["A6NDD5"],"Chromosome":"14","Position":"74405894-74426210","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"42","RNA tissue specific nTPM":{"brain":"468.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"2.5","Bipolar cells":"6.7","Horizontal cells":"11.5","Inhibitory neurons":"4.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"1.1"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"468.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"8","RNA mouse brain regional specific nTPM":{"basal ganglia":"280.7"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"7","RNA pig brain regional specific nTPM":{"basal ganglia":"125.1"},"Antibody":["HPA042594","HPA048487"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042594":"AB_2678069","HPA048487":"AB_2680416"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"}},{"Gene":"SYNE1","Gene synonym":["8B","ARCA1","C6orf98","CPG2","dJ45H2.2","enaptin","KIAA0796","MYNE1","Nesp1","Nesprin-1","SCAR8","SYNE-1B"],"Ensembl":"ENSG00000131018","Gene description":"Spectrin repeat containing nuclear envelope protein 1","Uniprot":["Q8NF91"],"Chromosome":"6","Position":"152121684-152637801","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Actin-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Emery-Dreifuss muscular dystrophy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"152.5","choroid plexus":"182.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"533.0","Bipolar cells":"352.9","Excitatory neurons":"487.8","Inhibitory neurons":"471.5","Microglial cells":"307.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"56.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"56.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019113"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"72000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA019113":"AB_1857707"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"}},{"Gene":"SYNE2","Gene synonym":["DKFZP434H2235","KIAA1011","Nesp2","Nesprin-2","NUA","NUANCE","SYNE-2"],"Ensembl":"ENSG00000054654","Gene description":"Spectrin repeat containing nuclear envelope protein 2","Uniprot":["Q8WXH0"],"Chromosome":"14","Position":"63761899-64226433","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Disease variant","Emery-Dreifuss muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"198.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"539.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"73.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"73.8","T-cells":"38.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003435","HPA050204"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Intermediate filaments"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nuclear membrane","Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA003435":"AB_1080162","HPA050204":"AB_2681051"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.56e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"}},{"Gene":"SYNE3","Gene synonym":["C14orf139","C14orf49","FLJ25605","LINC00341","NCRNA00341","Nesp3","Nesprin-3","NET53"],"Ensembl":"ENSG00000176438","Gene description":"Spectrin repeat containing nuclear envelope family member 3","Uniprot":["Q6ZMZ3"],"Chromosome":"14","Position":"95407266-95475836","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"19.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"46.5","monocytes":"48.8","Rod photoreceptor cells":"120.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"15.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055227","HPA077140"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA055227":"AB_2682747","HPA077140":"AB_2686826"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"}},{"Gene":"SYNE4","Gene synonym":["C19orf46","DFNB76","FLJ36445","Nesp4","Nesprin-4"],"Ensembl":"ENSG00000181392","Gene description":"Spectrin repeat containing nuclear envelope family member 4","Uniprot":["Q8N205"],"Chromosome":"19","Position":"36003307-36008813","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"34.5","Breast myoepithelial cells":"37.6","Cholangiocytes":"34.6","Cytotrophoblasts":"35.0","Syncytiotrophoblasts":"34.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"21.0","prostate cancer":"24.7"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"15","RNA mouse brain regional specific nTPM":{"cerebellum":"6.8"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060253"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060253":"AB_2684233"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.64e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"}},{"Gene":"SYNGR1","Gene synonym":[],"Ensembl":"ENSG00000100321","Gene description":"Synaptogyrin 1","Uniprot":["O43759"],"Chromosome":"22","Position":"39349925-39385575","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"177.1","Melanocytes":"177.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"19.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"44.7","monocytes":"38.9","T-cells":"30.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029673","CAB034277"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034277":"AB_2255766","HPA029673":"AB_10670430"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.41e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.98e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"SYNGR2","Gene synonym":[],"Ensembl":"ENSG00000108639","Gene description":"Synaptogyrin 2","Uniprot":["O43760"],"Chromosome":"17","Position":"78168581-78173527","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"388.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014742"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA014742":"AB_2669079"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.37e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"}},{"Gene":"SYNGR3","Gene synonym":[],"Ensembl":"ENSG00000127561","Gene description":"Synaptogyrin 3","Uniprot":["O43761"],"Chromosome":"16","Position":"1989660-1994275","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"122.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"23.8","Horizontal cells":"17.3","Inhibitory neurons":"32.9","Sertoli cells":"11.1","Spermatogonia":"10.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"1.9","NK-cells":"2.0","T-cells":"1.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034278","HPA042842"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB034278":"AB_2200905","HPA042842":"AB_2678198"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.92e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.12e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"}},{"Gene":"SYNGR4","Gene synonym":[],"Ensembl":"ENSG00000105467","Gene description":"Synaptogyrin 4","Uniprot":["O95473"],"Chromosome":"19","Position":"48364367-48376377","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"testis":"54.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Spermatocytes":"155.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"22.3"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030075","HPA059286"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 26: NCI-H716 - Unknown function","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA030075":"AB_10610559","HPA059286":"AB_2683965"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"}},{"Gene":"SYNJ2BP","Gene synonym":["Arip2"],"Ensembl":"ENSG00000213463","Gene description":"Synaptojanin 2 binding protein","Uniprot":["P57105"],"Chromosome":"14","Position":"70366499-70417090","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000866"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA000866":"AB_2276678"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"}},{"Gene":"SYNPR","Gene synonym":["MGC26651","SPO"],"Ensembl":"ENSG00000163630","Gene description":"Synaptoporin","Uniprot":["Q8TBG9"],"Chromosome":"3","Position":"63228315-63616924","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"123.6","retina":"38.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Inhibitory neurons":"623.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bone cancer":"9.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"743.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051368","HPA061671"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA051368":"AB_2681456","HPA061671":"AB_2684582"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"SYNRG","Gene synonym":["AP1GBP1","MGC104959","SYNG"],"Ensembl":"ENSG00000275066","Gene description":"Synergin gamma","Uniprot":["Q9UMZ2"],"Chromosome":"17","Position":"37514807-37609472","Protein class":["Predicted intracellular proteins"],"Biological process":["Endocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023554","HPA023555"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023554":"AB_1844892","HPA023555":"AB_2058337"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.96e-4"}},{"Gene":"SYP","Gene synonym":["MRX96"],"Ensembl":"ENSG00000102003","Gene description":"Synaptophysin","Uniprot":["P08247"],"Chromosome":"X","Position":"49187815-49200199","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"259.4","pituitary gland":"106.8","retina":"316.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"478.9","Cone photoreceptor cells":"468.7","Horizontal cells":"239.7","Rod photoreceptor cells":"599.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"12.8","pancreatic cancer":"5.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"56.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000076","HPA002858","CAB055505","CAB078999","HPA079659"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000076":"AB_2315411","CAB055505":"AB_564017","CAB078999":null,"HPA002858":"AB_1080153","HPA079659":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"}},{"Gene":"SYPL1","Gene synonym":["SYPL"],"Ensembl":"ENSG00000008282","Gene description":"Synaptophysin like 1","Uniprot":["Q16563"],"Chromosome":"7","Position":"106090505-106112576","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"669.2","Spermatocytes":"495.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014141"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014141":"AB_1857716"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"}},{"Gene":"SYPL2","Gene synonym":["Mg29"],"Ensembl":"ENSG00000143028","Gene description":"Synaptophysin like 2","Uniprot":["Q5VXT5"],"Chromosome":"1","Position":"109466546-109482134","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"skeletal muscle":"363.5","tongue":"175.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Skeletal myocytes":"53.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"2.7","Sarcoma":"3.3"},"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells","Skin - Sebaceous gland cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076657"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA076657":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-4"}},{"Gene":"SYS1","Gene synonym":["C20orf169","dJ453C12.4"],"Ensembl":"ENSG00000204070","Gene description":"SYS1 golgi trafficking protein","Uniprot":["Q8N2H4"],"Chromosome":"20","Position":"45361937-45376798","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046716"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046716":"AB_2679769"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"}},{"Gene":"SYT1","Gene synonym":["P65","SVP65","SYT"],"Ensembl":"ENSG00000067715","Gene description":"Synaptotagmin 1","Uniprot":["P21579"],"Chromosome":"12","Position":"78863993-79452008","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"403.3","retina":"197.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1074.2","Cone photoreceptor cells":"1132.2","Excitatory neurons":"3698.0","Horizontal cells":"806.2","Inhibitory neurons":"2844.8","Rod photoreceptor cells":"867.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"10","RNA brain regional specific nTPM":{"amygdala":"113.1","basal ganglia":"153.7","cerebral cortex":"403.3","hippocampal formation":"134.2","white matter":"146.0"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.0","naive B-cell":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"56.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008394","HPA064788"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008394":"AB_1857696","HPA064788":"AB_2685351"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"}},{"Gene":"SYT10","Gene synonym":[],"Ensembl":"ENSG00000110975","Gene description":"Synaptotagmin 10","Uniprot":["Q6XYQ8"],"Chromosome":"12","Position":"33374238-33439819","Protein class":["Predicted membrane proteins"],"Biological process":["Exocytosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"6.3","fallopian tube":"2.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"10.8","Distal tubular cells":"12.4","Horizontal cells":"10.9","Inhibitory neurons":"15.0","Late spermatids":"16.0","Schwann cells":"35.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"renal cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"49.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055426"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA055426":"AB_2682812"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-4"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"}},{"Gene":"SYT11","Gene synonym":["DKFZp781D015","KIAA0080","MGC10881","MGC17226"],"Ensembl":"ENSG00000132718","Gene description":"Synaptotagmin 11","Uniprot":["Q9BT88"],"Chromosome":"1","Position":"155859567-155885199","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"148.8","retina":"68.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"88.3","Bipolar cells":"70.3","Excitatory neurons":"82.3","Horizontal cells":"92.3","Inhibitory neurons":"101.9","Muller glia cells":"128.6","Oligodendrocyte precursor cells":"108.3","Oligodendrocytes":"125.7","Schwann cells":"84.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"glioma":"117.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"83.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064091"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064091":"AB_2685189"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.93e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"}},{"Gene":"SYT12","Gene synonym":["SRG1"],"Ensembl":"ENSG00000173227","Gene description":"Synaptotagmin 12","Uniprot":["Q8IV01"],"Chromosome":"11","Position":"67006778-67050863","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"22.5","liver":"17.6","parathyroid gland":"63.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"8.5","Basal respiratory cells":"11.0","Breast myoepithelial cells":"8.1","Excitatory neurons":"38.8","Inhibitory neurons":"21.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"8.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"33.8","cervical cancer":"44.7"},"RNA tissue cell type enrichment":["Prostate - Prostate basal glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011006","HPA074255"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011006":"AB_2286996","HPA074255":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.13e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"}},{"Gene":"SYT14","Gene synonym":["FLJ34198","sytXIV"],"Ensembl":"ENSG00000143469","Gene description":"Synaptotagmin 14","Uniprot":["Q8NB59"],"Chromosome":"1","Position":"209900923-210171389","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"7.0","retina":"1.9","testis":"3.2","thyroid gland":"5.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"205.7","Inhibitory neurons":"209.0","Oligodendrocyte precursor cells":"146.3","Oligodendrocytes":"186.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"1.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"7.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"4.7"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036963"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036963":"AB_10670378"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-5"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-3"}},{"Gene":"SYT15","Gene synonym":["CHR10SYT"],"Ensembl":"ENSG00000204176","Gene description":"Synaptotagmin 15","Uniprot":["Q9BQS2"],"Chromosome":"10","Position":"46578217-46594173","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"2.6","Alveolar cells type 1":"9.9","Alveolar cells type 2":"4.9","Endothelial cells":"4.8","Suprabasal keratinocytes":"2.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036971","HPA036972","HPA064559"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA036971":"AB_2675406","HPA036972":"AB_2675407","HPA064559":"AB_2685286"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-3"}},{"Gene":"SYT16","Gene synonym":["CHR14SYT","Strep14","SYT14L","yt14r"],"Ensembl":"ENSG00000139973","Gene description":"Synaptotagmin 16","Uniprot":["Q17RD7"],"Chromosome":"14","Position":"61811974-62112550","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"16.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"277.5","Inhibitory neurons":"272.9","Oligodendrocyte precursor cells":"121.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Beta cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004199","HPA076871"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA004199":"AB_1080156","HPA076871":"AB_2732324"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"}},{"Gene":"SYT2","Gene synonym":[],"Ensembl":"ENSG00000143858","Gene description":"Synaptotagmin 2","Uniprot":["Q8N9I0"],"Chromosome":"1","Position":"202590596-202710454","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"73.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"22.9","Horizontal cells":"28.2","Inhibitory neurons":"22.2","Oligodendrocytes":"7.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"testis cancer":"3.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"thyroid cancer":"8.2"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063655"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063655":"AB_2685077"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-3"}},{"Gene":"SYT3","Gene synonym":[],"Ensembl":"ENSG00000213023","Gene description":"Synaptotagmin 3","Uniprot":["Q9BQG1"],"Chromosome":"19","Position":"50621307-50639881","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"28.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"5.2","Excitatory neurons":"10.3","Inhibitory neurons":"15.2","Oligodendrocyte precursor cells":"5.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"5.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"}},{"Gene":"SYT4","Gene synonym":["HsT1192","KIAA1342"],"Ensembl":"ENSG00000132872","Gene description":"Synaptotagmin 4","Uniprot":["Q9H2B2"],"Chromosome":"18","Position":"43267892-43277535","Protein class":["Predicted intracellular proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"74.7","pituitary gland":"30.7","retina":"25.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"56.2","Cone photoreceptor cells":"19.0","Excitatory neurons":"50.2","Horizontal cells":"34.6","Inhibitory neurons":"33.3","Thymic epithelial cells":"38.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"2.0","pancreatic cancer":"4.1","prostate cancer":"1.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"53.0","prostate cancer":"42.0"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010574"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA010574":"AB_2668309"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"SYT5","Gene synonym":[],"Ensembl":"ENSG00000129990","Gene description":"Synaptotagmin 5","Uniprot":["O00445"],"Chromosome":"19","Position":"55171196-55180289","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"72.6","pituitary gland":"59.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"22.6","Excitatory neurons":"20.0","Inhibitory neurons":"11.6","Late spermatids":"45.8","Pancreatic endocrine cells":"12.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"3.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"28.1","Rhabdoid":"32.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Late spermatids","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078390"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078390":"AB_2732382"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.54e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.54e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"}},{"Gene":"SYT6","Gene synonym":[],"Ensembl":"ENSG00000134207","Gene description":"Synaptotagmin 6","Uniprot":["Q5T7P8"],"Chromosome":"1","Position":"114089291-114153880","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"13.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"5.8","Horizontal cells":"26.3","Late spermatids":"14.9","Microglial cells":"26.5","Oligodendrocyte precursor cells":"7.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"5.8"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Proximal tubular cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"basal ganglia":"31.2","olfactory bulb":"71.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058362"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA058362":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"}},{"Gene":"SYT7","Gene synonym":["IPCA-7","MGC150517","PCANAP7","SYT-VII"],"Ensembl":"ENSG00000011347","Gene description":"Synaptotagmin 7","Uniprot":["O43581"],"Chromosome":"11","Position":"61513714-61581148","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Exocytosis"],"Molecular function":["Calmodulin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"78.4","liver":"86.7","salivary gland":"57.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"51.8","Enteroendocrine cells":"49.8","Excitatory neurons":"80.9","Hepatocytes":"60.8","Horizontal cells":"78.2","Prostatic glandular cells":"107.1","Syncytiotrophoblasts":"77.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"54.4"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"78.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"38.0"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Kidney - Ascending Loop of Henle cells","Pancreas - Alpha cells","Pancreas - Beta cells","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012869"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012869":"AB_1857698"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"}},{"Gene":"SYT8","Gene synonym":["DKFZp434K0322"],"Ensembl":"ENSG00000149043","Gene description":"Synaptotagmin 8","Uniprot":["Q8NBV8"],"Chromosome":"11","Position":"1828307-1837521","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"29.2","skin 1":"65.5","urinary bladder":"40.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal keratinocytes":"127.3","Basal squamous epithelial cells":"303.9","Breast myoepithelial cells":"259.9","Cholangiocytes":"194.4","Extravillous trophoblasts":"242.7","Respiratory ciliated cells":"172.2","Squamous epithelial cells":"113.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"cervical cancer":"10.5","pancreatic cancer":"21.7","urothelial cancer":"33.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"10.3","pancreatic cancer":"8.2"},"RNA tissue cell type enrichment":["Liver - Cholangiocyte","Lung - Respiratory ciliated cells","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047239","HPA052700"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nucleoli fibrillar center","Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA047239":null,"HPA052700":"AB_2681920"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"}},{"Gene":"SYT9","Gene synonym":[],"Ensembl":"ENSG00000170743","Gene description":"Synaptotagmin 9","Uniprot":["Q86SS6"],"Chromosome":"11","Position":"7238778-7469043","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"15.9","retina":"7.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"47.1","Late spermatids":"26.2","Oligodendrocyte precursor cells":"52.9","Oligodendrocytes":"131.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"2.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Neuroblastoma":"7.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Proximal tubular cells","Skin - Keratinocyte (other)","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-4"}},{"Gene":"SYVN1","Gene synonym":["DER3","HRD1"],"Ensembl":"ENSG00000162298","Gene description":"Synoviolin 1","Uniprot":["Q86TM6"],"Chromosome":"11","Position":"65121780-65134532","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Stress response","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"136.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005480","HPA024300","CAB037030"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Endoplasmic reticulum","Plasma membrane"],"Antibody RRID":{"CAB037030":"AB_1840939","HPA005480":"AB_1079084","HPA024300":"AB_1851073"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.88e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"}},{"Gene":"TAAR1","Gene synonym":["TA1","TAR1","TRAR1"],"Ensembl":"ENSG00000146399","Gene description":"Trace amine associated receptor 1","Uniprot":["Q96RJ0"],"Chromosome":"6","Position":"132644898-132646051","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"stomach 1":"6.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"1.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"pancreatic cancer":"3.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055614"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055614":"AB_2682862"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAAR2","Gene synonym":["GPR58"],"Ensembl":"ENSG00000146378","Gene description":"Trace amine associated receptor 2","Uniprot":["Q9P1P5"],"Chromosome":"6","Position":"132617022-132624275","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1.7","Late spermatids":"2.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAAR5","Gene synonym":["PNR"],"Ensembl":"ENSG00000135569","Gene description":"Trace amine associated receptor 5","Uniprot":["O14804"],"Chromosome":"6","Position":"132588673-132589686","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051703"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051703":"AB_2681580"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAAR6","Gene synonym":["TA4","TRAR4"],"Ensembl":"ENSG00000146383","Gene description":"Trace amine associated receptor 6","Uniprot":["Q96RI8"],"Chromosome":"6","Position":"132570322-132571359","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAAR8","Gene synonym":["GPR102","TA5","TAR5","TRAR5"],"Ensembl":"ENSG00000146385","Gene description":"Trace amine associated receptor 8","Uniprot":["Q969N4"],"Chromosome":"6","Position":"132552693-132553721","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAAR9","Gene synonym":["TA3","TAR3","TRAR3"],"Ensembl":"ENSG00000237110","Gene description":"Trace amine associated receptor 9","Uniprot":["Q96RI9"],"Chromosome":"6","Position":"132538290-132539336","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TACR1","Gene synonym":["NK1R","NKIR","SPR","TAC1R"],"Ensembl":"ENSG00000115353","Gene description":"Tachykinin receptor 1","Uniprot":["P25103"],"Chromosome":"2","Position":"75046463-75199520","Protein class":["FDA approved drug targets","G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Inhibitory neurons":"81.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"23","RNA blood cell specific nTPM":{"basophil":"2.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"granulocytes":"2.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"2.3","ovarian cancer":"1.3"},"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Prostate - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074573"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074573":"AB_2686701"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"}},{"Gene":"TACR2","Gene synonym":["NK2R","NKNAR","SKR","TAC2R"],"Ensembl":"ENSG00000075073","Gene description":"Tachykinin receptor 2","Uniprot":["P21452"],"Chromosome":"10","Position":"69403903-69416918","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"184.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"2.4","Serous glandular cells":"2.4","Sertoli cells":"2.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"stomach cancer":"6.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076573"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA076573":"AB_2732313"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"TACR3","Gene synonym":["NK3R","NKR","TAC3R"],"Ensembl":"ENSG00000169836","Gene description":"Tachykinin receptor 3","Uniprot":["P29371"],"Chromosome":"4","Position":"103586031-103719985","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.4","retina":"2.7","urinary bladder":"1.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Bipolar cells":"11.7","Excitatory neurons":"6.6","Extravillous trophoblasts":"5.5","Oligodendrocytes":"9.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"pons":"8.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"22","RNA cell line specific nTPM":{"Sarcoma":"3.0"},"RNA tissue cell type enrichment":["Kidney - Podocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009418"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA009418":"AB_1857727"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"}},{"Gene":"TACSTD2","Gene synonym":["EGP-1","GA733-1","M1S1","TROP2"],"Ensembl":"ENSG00000184292","Gene description":"Tumor associated calcium signal transducer 2","Uniprot":["P09758"],"Chromosome":"1","Position":"58575433-58577252","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Sensory transduction","Vision"],"Molecular function":["Tumor antigen"],"Disease involvement":["Amyloidosis","Corneal dystrophy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"989.6","salivary gland":"468.5","skin 1":"438.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"1685.3","Basal respiratory cells":"2892.6","Basal squamous epithelial cells":"1804.4","Club cells":"2016.7","Ductal cells":"1941.6","Ionocytes":"2053.2","Squamous epithelial cells":"2789.0","Suprabasal keratinocytes":"2443.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"15.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"79","RNA blood lineage specific nTPM":{"dendritic cells":"4.3","granulocytes":"15.0","monocytes":"4.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"923.2"},"RNA tissue cell type enrichment":["Liver - Cholangiocyte","Pancreas - Ductal cells","Prostate - Prostate basal glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043104","HPA055067","CAB072852"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli","Vesicles"],"Antibody RRID":{"CAB072852":null,"HPA043104":"AB_10960710","HPA055067":"AB_2682687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.99e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"}},{"Gene":"TAF15","Gene synonym":["hTAFII68","Npl3","RBP56","TAF2N"],"Ensembl":"ENSG00000270647","Gene description":"TATA-box binding protein associated factor 15","Uniprot":["Q92804"],"Chromosome":"17","Position":"35713791-35864615","Protein class":["Cancer-related genes","Disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["DNA-binding","RNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052059","HPA063647"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"44000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA052059":"AB_2681711","HPA063647":"AB_2685072"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"}},{"Gene":"TAF1B","Gene synonym":["RAF1B","RAFI63","SL1","TAFI63"],"Ensembl":"ENSG00000115750","Gene description":"TATA-box binding protein associated factor, RNA polymerase I subunit B","Uniprot":["Q53T94"],"Chromosome":"2","Position":"9843443-9934416","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071254"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA071254":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.58e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.94e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.55e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"}},{"Gene":"TAF1C","Gene synonym":["MGC:39976","SL1","TAFI110","TAFI95"],"Ensembl":"ENSG00000103168","Gene description":"TATA-box binding protein associated factor, RNA polymerase I subunit C","Uniprot":["Q15572"],"Chromosome":"16","Position":"84177847-84187070","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072229"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA072229":"AB_2686499"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.76e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.08e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.22e-4"}},{"Gene":"TAF1D","Gene synonym":["JOSD3","MGC5306","TAF(I)41"],"Ensembl":"ENSG00000166012","Gene description":"TATA-box binding protein associated factor, RNA polymerase I subunit D","Uniprot":["Q9H5J8"],"Chromosome":"11","Position":"93729948-93784391","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030703","HPA055935","HPA060385"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Mitotic spindle","Centriolar satellite"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Mitotic spindle","Centriolar satellite"],"Antibody RRID":{"HPA030703":null,"HPA055935":"AB_2682974","HPA060385":"AB_2684271"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.17e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"}},{"Gene":"TAFA5","Gene synonym":["FAM19A5","TAFA-5"],"Ensembl":"ENSG00000219438","Gene description":"TAFA chemokine like family member 5","Uniprot":["Q7Z5A7"],"Chromosome":"22","Position":"48489553-48850912","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"85.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"63.6","Endometrial stromal cells":"32.9","Excitatory neurons":"47.8","Granulosa cells":"43.2","Inhibitory neurons":"75.5","Muller glia cells":"35.4","Oligodendrocyte precursor cells":"58.2","Oligodendrocytes":"44.1","Schwann cells":"54.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"13.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Bone cancer":"35.8","Neuroblastoma":"20.9"},"RNA tissue cell type enrichment":["Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025629"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025629":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"}},{"Gene":"TANGO6","Gene synonym":["FLJ12688","KIAA1746","TMCO7"],"Ensembl":"ENSG00000103047","Gene description":"Transport and golgi organization 6 homolog","Uniprot":["Q9C0B7"],"Chromosome":"16","Position":"68843531-69085182","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"22.8","Early spermatids":"65.2","Excitatory neurons":"44.7","Inhibitory neurons":"56.0","Late spermatids":"82.5","Microglial cells":"24.6","Oligodendrocyte precursor cells":"37.1","Oligodendrocytes":"48.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041312"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA041312":"AB_10796342"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"}},{"Gene":"TANK","Gene synonym":["I-TRAF","TRAF2"],"Ensembl":"ENSG00000136560","Gene description":"TRAF family member associated NFKB activator","Uniprot":["Q92844"],"Chromosome":"2","Position":"161136908-161236230","Protein class":["Predicted intracellular proteins"],"Biological process":["DNA damage","Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"220.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010345","HPA037675","HPA037676"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB010345":"AB_2199871","HPA037675":"AB_2675600","HPA037676":"AB_2675601"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"}},{"Gene":"TAOK2","Gene synonym":["KIAA0881","MAP3K17","PSK","PSK1","TAO1","TAO2"],"Ensembl":"ENSG00000149930","Gene description":"TAO kinase 2","Uniprot":["Q9UL54"],"Chromosome":"16","Position":"29973868-29992261","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"50.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010650"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA010650":"AB_1080204"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.51e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.87e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.78e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"TAP1","Gene synonym":["ABCB2","D6S114E","PSF1","RING4"],"Ensembl":"ENSG00000168394","Gene description":"Transporter 1, ATP binding cassette subfamily B member","Uniprot":["Q03518"],"Chromosome":"6","Position":"32845209-32853816","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Peptide transport","Protein transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"124.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Skin - Keratinocyte (other)","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009516","HPA072354"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Endoplasmic reticulum","Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"CAB009516":"AB_2303048","HPA072354":"AB_2686513"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.01e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.07e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"}},{"Gene":"TAP2","Gene synonym":["ABCB3","D6S217E","PSF2","RING11"],"Ensembl":"ENSG00000204267","Gene description":"Transporter 2, ATP binding cassette subfamily B member","Uniprot":["Q03519"],"Chromosome":"6","Position":"32821833-32838770","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Peptide transport","Protein transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001312"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA001312":"AB_1080206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.51e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.22e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"}},{"Gene":"TAPBP","Gene synonym":["TAPA"],"Ensembl":"ENSG00000231925","Gene description":"TAP binding protein","Uniprot":["O15533"],"Chromosome":"6","Position":"33299694-33314387","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007066"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007066":"AB_1857769"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.29e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-3"}},{"Gene":"TAPBPL","Gene synonym":["FLJ10143","TAPBP-R","TAPBPR"],"Ensembl":"ENSG00000139192","Gene description":"TAP binding protein like","Uniprot":["Q9BX59"],"Chromosome":"12","Position":"6451690-6466517","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"86.1","Proximal enterocytes":"79.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039545"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 34: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039545":"AB_10673360"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.98e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.04e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.86e-4"}},{"Gene":"TAPT1","Gene synonym":["FLJ90013"],"Ensembl":"ENSG00000169762","Gene description":"Transmembrane anterior posterior transformation 1","Uniprot":["Q6NXT6"],"Chromosome":"4","Position":"16160505-16227410","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Chondrogenesis","Cilium biogenesis\/degradation","Differentiation","Host-virus interaction","Osteogenesis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Ciliopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"148.2","Late spermatids":"179.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042567"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Centrosome"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA042567":"AB_2678055"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.75e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.34e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.52e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.18e-4"}},{"Gene":"TARM1","Gene synonym":[],"Ensembl":"ENSG00000248385","Gene description":"T cell-interacting, activating receptor on myeloid cells 1","Uniprot":["B6A8C7"],"Chromosome":"19","Position":"54069895-54081365","Protein class":["Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"bone marrow":"6.9"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Neutrophil_1"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051022","HPA054401"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051022":"AB_2681315","HPA054401":"AB_2682476"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TARS1","Gene synonym":["TARS"],"Ensembl":"ENSG00000113407","Gene description":"Threonyl-tRNA synthetase 1","Uniprot":["P26639"],"Chromosome":"5","Position":"33440696-33468091","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase","RNA-binding","tRNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037425"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"580000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Cytosol"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA037425":"AB_10672279"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.14e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.88e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"}},{"Gene":"TAS1R1","Gene synonym":["GPR70","T1R1","TR1"],"Ensembl":"ENSG00000173662","Gene description":"Taste 1 receptor member 1","Uniprot":["Q7RTX1"],"Chromosome":"1","Position":"6555307-6579755","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"4.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"5.0","Late spermatids":"17.5","Schwann cells":"4.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"1.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034579","HPA034580"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034579":"AB_2674232","HPA034580":"AB_10671504"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"}},{"Gene":"TAS1R2","Gene synonym":["GPR71","T1R2","TR2"],"Ensembl":"ENSG00000179002","Gene description":"Taste 1 receptor member 2","Uniprot":["Q8TE23"],"Chromosome":"1","Position":"18839599-18859682","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS1R3","Gene synonym":["T1R3"],"Ensembl":"ENSG00000169962","Gene description":"Taste 1 receptor member 3","Uniprot":["Q7RTX0"],"Chromosome":"1","Position":"1331280-1335314","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"12.1","salivary gland":"7.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"1.7","Distal enterocytes":"2.1","Plasma cells":"6.6","Serous glandular cells":"3.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"17","RNA blood cell specific nTPM":{"memory B-cell":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"B-cells":"1.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"8.1"},"RNA tissue cell type enrichment":["Breast - Plasma cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053439"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053439":"AB_2682150"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"TAS2R1","Gene synonym":["T2R1","TRB7"],"Ensembl":"ENSG00000169777","Gene description":"Taste 2 receptor member 1","Uniprot":["Q9NYW7"],"Chromosome":"5","Position":"9627347-9712378","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"7.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nTPM":{"Early spermatids":"25.5","Late spermatids":"76.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051879"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051879":"AB_2681649"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS2R10","Gene synonym":["T2R10","TRB2"],"Ensembl":"ENSG00000121318","Gene description":"Taste 2 receptor member 10","Uniprot":["Q9NYW0"],"Chromosome":"12","Position":"10825317-10826358","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"23","RNA single cell type specific nTPM":{"Astrocytes":"6.0","Excitatory neurons":"14.2","Inhibitory neurons":"14.1","Microglial cells":"4.6","Oligodendrocyte precursor cells":"13.5","Oligodendrocytes":"10.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070201"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA070201":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"}},{"Gene":"TAS2R13","Gene synonym":["T2R13","TRB3"],"Ensembl":"ENSG00000212128","Gene description":"Taste 2 receptor member 13","Uniprot":["Q9NYV9"],"Chromosome":"12","Position":"10907926-10909562","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS2R14","Gene synonym":["T2R14","TRB1"],"Ensembl":"ENSG00000212127","Gene description":"Taste 2 receptor member 14","Uniprot":["Q9NYV8"],"Chromosome":"12","Position":"10937408-11171573","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"6.2","Horizontal cells":"7.0","Rod photoreceptor cells":"7.4","Skeletal myocytes":"6.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-3"}},{"Gene":"TAS2R16","Gene synonym":["T2R16"],"Ensembl":"ENSG00000128519","Gene description":"Taste 2 receptor member 16","Uniprot":["Q9NYV7"],"Chromosome":"7","Position":"122994704-122995700","Protein class":["G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS2R19","Gene synonym":["T2R19","T2R23","TAS2R23","TAS2R48"],"Ensembl":"ENSG00000212124","Gene description":"Taste 2 receptor member 19","Uniprot":["P59542"],"Chromosome":"12","Position":"11021619-11022620","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Prostatic glandular cells":"1.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-1"}},{"Gene":"TAS2R20","Gene synonym":["T2R20","T2R56","TAS2R49"],"Ensembl":"ENSG00000255837","Gene description":"Taste 2 receptor member 20","Uniprot":["P59543"],"Chromosome":"12","Position":"10996495-10997875","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-3"}},{"Gene":"TAS2R3","Gene synonym":["T2R3"],"Ensembl":"ENSG00000127362","Gene description":"Taste 2 receptor member 3","Uniprot":["Q9NYW6"],"Chromosome":"7","Position":"141764097-141765197","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"3.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS2R30","Gene synonym":["T2R30","TAS2R47"],"Ensembl":"ENSG00000256188","Gene description":"Taste 2 receptor member 30","Uniprot":["P59541"],"Chromosome":"12","Position":"11132958-11134644","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"2.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"1.7","Rod photoreceptor cells":"2.0","Skeletal myocytes":"4.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-1"}},{"Gene":"TAS2R31","Gene synonym":["T2R31","T2R53","TAS2R44"],"Ensembl":"ENSG00000256436","Gene description":"Taste 2 receptor member 31","Uniprot":["P59538"],"Chromosome":"12","Position":"11030387-11031407","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.3","Endothelial cells":"1.6","Granulosa cells":"1.5","Horizontal cells":"1.3","monocytes":"1.3","Prostatic glandular cells":"1.1","Rod photoreceptor cells":"1.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"}},{"Gene":"TAS2R38","Gene synonym":["PTC","T2R61"],"Ensembl":"ENSG00000257138","Gene description":"Taste 2 receptor member 38","Uniprot":["P59533"],"Chromosome":"7","Position":"141972631-141973773","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"1.9","lung cancer":"1.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043862","HPA054366"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043862":"AB_2678703","HPA054366":"AB_2682464"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"}},{"Gene":"TAS2R39","Gene synonym":[],"Ensembl":"ENSG00000236398","Gene description":"Taste 2 receptor member 39","Uniprot":["P59534"],"Chromosome":"7","Position":"143183419-143184435","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"90","RNA tissue specific nTPM":{"brain":"8.9"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060680"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060680":"AB_2684341"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS2R4","Gene synonym":["T2R4"],"Ensembl":"ENSG00000127364","Gene description":"Taste 2 receptor member 4","Uniprot":["Q9NYW5"],"Chromosome":"7","Position":"141776674-141781691","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"7.8","Horizontal cells":"8.3","Prostatic glandular cells":"6.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"}},{"Gene":"TAS2R40","Gene synonym":["GPR60"],"Ensembl":"ENSG00000221937","Gene description":"Taste 2 receptor member 40","Uniprot":["P59535"],"Chromosome":"7","Position":"143222037-143223079","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"11.4"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"neutrophil":"2.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"2.8"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS2R41","Gene synonym":["T2R59"],"Ensembl":"ENSG00000221855","Gene description":"Taste 2 receptor member 41","Uniprot":["P59536"],"Chromosome":"7","Position":"143477873-143478796","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057063"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057063":"AB_2683324"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS2R42","Gene synonym":["hT2R55","T2R24","T2R55","TAS2R55"],"Ensembl":"ENSG00000186136","Gene description":"Taste 2 receptor member 42","Uniprot":["Q7RTR8"],"Chromosome":"12","Position":"11185993-11186937","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036149"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036149":"AB_10672080"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS2R43","Gene synonym":["T2R52"],"Ensembl":"ENSG00000255374","Gene description":"Taste 2 receptor member 43","Uniprot":["P59537"],"Chromosome":"12","Position":"11091287-11092313","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"}},{"Gene":"TAS2R46","Gene synonym":["T2R54"],"Ensembl":"ENSG00000226761","Gene description":"Taste 2 receptor member 46","Uniprot":["P59540"],"Chromosome":"12","Position":"11061365-11062294","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-4"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS2R5","Gene synonym":["T2R5"],"Ensembl":"ENSG00000127366","Gene description":"Taste 2 receptor member 5","Uniprot":["Q9NYW4"],"Chromosome":"7","Position":"141790217-141791367","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053742"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Cytoplasmic bodies"],"Antibody RRID":{"HPA053742":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"}},{"Gene":"TAS2R50","Gene synonym":["T2R51"],"Ensembl":"ENSG00000212126","Gene description":"Taste 2 receptor member 50","Uniprot":["P59544"],"Chromosome":"12","Position":"10985913-10986912","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS2R60","Gene synonym":["T2R60"],"Ensembl":"ENSG00000185899","Gene description":"Taste 2 receptor member 60","Uniprot":["P59551"],"Chromosome":"7","Position":"143443453-143444409","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030416"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030416":"AB_10603344"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS2R7","Gene synonym":["T2R7","TRB4"],"Ensembl":"ENSG00000121377","Gene description":"Taste 2 receptor member 7","Uniprot":["Q9NYW3"],"Chromosome":"12","Position":"10801532-10802627","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS2R8","Gene synonym":["T2R8","TRB5"],"Ensembl":"ENSG00000121314","Gene description":"Taste 2 receptor member 8","Uniprot":["Q9NYW2"],"Chromosome":"12","Position":"10806051-10807286","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TAS2R9","Gene synonym":["T2R9","TRB6"],"Ensembl":"ENSG00000121381","Gene description":"Taste 2 receptor member 9","Uniprot":["Q9NYW1"],"Chromosome":"12","Position":"10809094-10810168","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Sensory transduction","Taste"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TATDN1","Gene synonym":["CDA11"],"Ensembl":"ENSG00000147687","Gene description":"TatD DNase domain containing 1","Uniprot":["Q6P1N9"],"Chromosome":"8","Position":"124488485-124539458","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023634","HPA053045"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"660000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA023634":"AB_1857779","HPA053045":"AB_2682024"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"}},{"Gene":"TAX1BP1","Gene synonym":["CALCOCO3","TXBP151"],"Ensembl":"ENSG00000106052","Gene description":"Tax1 binding protein 1","Uniprot":["Q86VP1"],"Chromosome":"7","Position":"27739331-27844564","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"970.0","Syncytiotrophoblasts":"804.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024432"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA024432":"AB_1857783"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.80e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"}},{"Gene":"TAZ","Gene synonym":["BTHS","CMD3A","EFE","EFE2","G4.5","TAZ1","XAP-2"],"Ensembl":"ENSG00000102125","Gene description":"Tafazzin","Uniprot":["Q16635"],"Chromosome":"X","Position":"154411524-154421726","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039557"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA039557":"AB_10672899"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.70e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.22e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"}},{"Gene":"TBC1D13","Gene synonym":["FLJ10743"],"Ensembl":"ENSG00000107021","Gene description":"TBC1 domain family member 13","Uniprot":["Q9NVG8"],"Chromosome":"9","Position":"128787253-128810430","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"34.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"23.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045865"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9300","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA045865":"AB_10965700"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.14e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.58e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"}},{"Gene":"TBC1D14","Gene synonym":["KIAA1322"],"Ensembl":"ENSG00000132405","Gene description":"TBC1 domain family member 14","Uniprot":["Q9P2M4"],"Chromosome":"4","Position":"6909242-7033118","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Stomach - Parietal cells","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036930","HPA067398"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA036930":"AB_10670155","HPA067398":"AB_2685833"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.28e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"}},{"Gene":"TBC1D19","Gene synonym":["FLJ11082"],"Ensembl":"ENSG00000109680","Gene description":"TBC1 domain family member 19","Uniprot":["Q8N5T2"],"Chromosome":"4","Position":"26576437-26756223","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"64.8","Excitatory neurons":"105.1","Inhibitory neurons":"93.1","Oligodendrocyte precursor cells":"98.2","Oligodendrocytes":"68.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039592"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA039592":"AB_10671043"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.21e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.06e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"}},{"Gene":"TBC1D20","Gene synonym":["C20orf140","dJ852M4.2"],"Ensembl":"ENSG00000125875","Gene description":"TBC1 domain family member 20","Uniprot":["Q96BZ9"],"Chromosome":"20","Position":"423596-462566","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"144.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043613"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043613":"AB_10963930"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"}},{"Gene":"TBC1D23","Gene synonym":["FLJ11046"],"Ensembl":"ENSG00000036054","Gene description":"TBC1 domain family member 23","Uniprot":["Q9NUY8"],"Chromosome":"3","Position":"100260992-100325251","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038151","HPA038152"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA038151":"AB_10672405","HPA038152":"AB_10672620"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.37e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"}},{"Gene":"TBC1D25","Gene synonym":["OATL1"],"Ensembl":"ENSG00000068354","Gene description":"TBC1 domain family member 25","Uniprot":["Q3MII6"],"Chromosome":"X","Position":"48539714-48562609","Protein class":["Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"35.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029197"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Approved","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029197":"AB_2672945"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"}},{"Gene":"TBC1D2B","Gene synonym":["KIAA1055"],"Ensembl":"ENSG00000167202","Gene description":"TBC1 domain family member 2B","Uniprot":["Q9UPU7"],"Chromosome":"15","Position":"77984036-78077724","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"69.9","Theca cells":"76.1","Thymic epithelial cells":"73.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041833","HPA048174","HPA052663"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041833":"AB_2732494","HPA048174":"AB_2680297","HPA052663":"AB_2681906"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"}},{"Gene":"TBC1D30","Gene synonym":["KIAA0984"],"Ensembl":"ENSG00000111490","Gene description":"TBC1 domain family member 30","Uniprot":["Q9Y2I9"],"Chromosome":"12","Position":"64759484-64881033","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.1","pancreas":"12.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"30.5","Inhibitory neurons":"41.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Heart muscle - Endothelial cells","Skeletal muscle - Endothelial cells","Stomach - Chief cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039772","HPA040043"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA039772":"AB_10795409","HPA040043":"AB_10795411"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.61e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.08e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-3"}},{"Gene":"TBC1D32","Gene synonym":["bA57L9.1","BROMI","C6orf170","C6orf171","dJ310J6.1","FLJ30899","FLJ34235"],"Ensembl":"ENSG00000146350","Gene description":"TBC1 domain family member 32","Uniprot":["Q96NH3"],"Chromosome":"6","Position":"121079494-121334745","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"7.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"66.1","Excitatory neurons":"122.2","Inhibitory neurons":"85.3","Oligodendrocyte precursor cells":"101.1","Oligodendrocytes":"96.8","Rod photoreceptor cells":"113.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013413"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA013413":"AB_10602702"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"}},{"Gene":"TBC1D3B","Gene synonym":["PRC17","TBC1D3I"],"Ensembl":"ENSG00000274808","Gene description":"TBC1 domain family member 3B","Uniprot":["A6NDS4"],"Chromosome":"17","Position":"36165681-36176636","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"13.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"15.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046969","HPA047745","HPA052553"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046969":null,"HPA047745":"AB_2680144","HPA052553":"AB_2681869"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"TBC1D5","Gene synonym":["KIAA0210"],"Ensembl":"ENSG00000131374","Gene description":"TBC1 domain family member 5","Uniprot":["Q92609"],"Chromosome":"3","Position":"17157162-18444817","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy","Protein transport","Transport"],"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"219.5","Excitatory neurons":"328.3","Inhibitory neurons":"342.8","Microglial cells":"315.6","Oligodendrocyte precursor cells":"327.3","Oligodendrocytes":"533.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035125","HPA035126"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA035125":"AB_2674479","HPA035126":"AB_10670696"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.75e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"}},{"Gene":"TBC1D7","Gene synonym":["dJ257A7.3","FLJ32666"],"Ensembl":"ENSG00000145979","Gene description":"TBC1 domain family member 7","Uniprot":["Q9P0N9"],"Chromosome":"6","Position":"13266542-13328583","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"67.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"13.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"196.5"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034748"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034748":"AB_10671232"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.98e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.03e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"}},{"Gene":"TBC1D8","Gene synonym":["AD3","GRAMD8","HBLP1","VRP"],"Ensembl":"ENSG00000204634","Gene description":"TBC1 domain family member 8","Uniprot":["O95759"],"Chromosome":"2","Position":"101007228-101252866","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"105.7","monocytes":"139.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"30.1","non-classical monocyte":"38.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"38.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015211","HPA037496"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 30: Breast - Lactation","Subcellular main location":["Nucleoplasm","Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"CAB015211":null,"HPA037496":"AB_2675507"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.73e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-3"}},{"Gene":"TBCA","Gene synonym":[],"Ensembl":"ENSG00000171530","Gene description":"Tubulin folding cofactor A","Uniprot":["O75347"],"Chromosome":"5","Position":"77691166-77868780","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"1369.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036487"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Microtubules"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA036487":"AB_10669794"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"}},{"Gene":"TBCB","Gene synonym":["CG22","CKAP1","CKAPI"],"Ensembl":"ENSG00000105254","Gene description":"Tubulin folding cofactor B","Uniprot":["Q99426"],"Chromosome":"19","Position":"36114289-36125947","Protein class":["Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Chaperone","Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"448.6"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041428","HPA041722"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041428":"AB_10794517","HPA041722":"AB_10804007"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.09e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.11e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"TBCD","Gene synonym":[],"Ensembl":"ENSG00000141556","Gene description":"Tubulin folding cofactor D","Uniprot":["Q9BTW9"],"Chromosome":"17","Position":"82752065-82945914","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone","GTPase activation"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045200"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6200","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045200":"AB_10969134"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.39e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"}},{"Gene":"TBCE","Gene synonym":["HRD","KCS","KCS1","pac2"],"Ensembl":"ENSG00000284770","Gene description":"Tubulin folding cofactor E","Uniprot":["Q15813"],"Chromosome":"1","Position":"235367360-235452443","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Disease variant","Dwarfism","Intellectual disability","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"15.5","Rod photoreceptor cells":"18.4"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026552","HPA026557"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026552":"AB_1857797","HPA026557":"AB_1857798"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TBRG4","Gene synonym":["Cpr2","FASTKD4","H_TD2522F11.8","KIAA0948"],"Ensembl":"ENSG00000136270","Gene description":"Transforming growth factor beta regulator 4","Uniprot":["Q969Z0"],"Chromosome":"7","Position":"45100100-45112047","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020582","HPA050430"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"23000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA020582":"AB_1857804","HPA050430":"AB_2681125"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.40e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"}},{"Gene":"TBX3","Gene synonym":["TBX3-ISO","UMS","XHL"],"Ensembl":"ENSG00000135111","Gene description":"T-box transcription factor 3","Uniprot":["O15119"],"Chromosome":"12","Position":"114670255-114684175","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"178.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"393.8","Endometrial stromal cells":"144.0","Prostatic glandular cells":"225.2","Syncytiotrophoblasts":"658.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"49.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"79.7","prostate cancer":"68.4"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005799","HPA075876"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA005799":"AB_1857817","HPA075876":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.28e-4"}},{"Gene":"TBXA2R","Gene synonym":[],"Ensembl":"ENSG00000006638","Gene description":"Thromboxane A2 receptor","Uniprot":["P21731"],"Chromosome":"19","Position":"3594507-3606875","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"10.6","Endothelial cells":"9.4","Fibroblasts":"4.8","Schwann cells":"7.4","Smooth muscle cells":"7.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"11.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077366"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA077366":"AB_2686836"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.17e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"}},{"Gene":"TBXAS1","Gene synonym":["CYP5","CYP5A1","THAS","TS","TXAS","TXS"],"Ensembl":"ENSG00000059377","Gene description":"Thromboxane A synthase 1","Uniprot":["P24557"],"Chromosome":"7","Position":"139777051-140020325","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Prostaglandin biosynthesis","Prostaglandin metabolism"],"Molecular function":["Isomerase","Lyase","Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"57.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"granulocytes":"49.2","Hofbauer cells":"110.0","Kupffer cells":"175.8","Macrophages":"137.3","Microglial cells":"186.1","monocytes":"150.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"basophil":"324.3","classical monocyte":"322.4","eosinophil":"333.6","intermediate monocyte":"466.0","myeloid DC":"129.0","neutrophil":"271.1","non-classical monocyte":"423.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"dendritic cells":"129.0","granulocytes":"333.6","monocytes":"466.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"15.9","Leukemia":"16.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Lung - Macrophages","Pancreas - Macrophages","Skeletal muscle - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031257","HPA031258","HPA031259"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"890000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA031257":"AB_2673812","HPA031258":"AB_2673813","HPA031259":"AB_2673814"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"}},{"Gene":"TCAF2","Gene synonym":["FAM115C","FAM139A","FLJ40722","GATD9"],"Ensembl":"ENSG00000170379","Gene description":"TRPM8 channel associated factor 2","Uniprot":["A6NFQ2"],"Chromosome":"7","Position":"143620952-143730409","Protein class":["Predicted intracellular proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"12.9","Hepatocytes":"10.2","Suprabasal keratinocytes":"7.7","Syncytiotrophoblasts":"16.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Kidney - Endothelial cells","Lung - Fibroblast_1"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038756","HPA038758"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA038756":"AB_10960427","HPA038758":"AB_10960353"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.53e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.17e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"}},{"Gene":"TCEANC2","Gene synonym":["C1orf83","FLJ32112"],"Ensembl":"ENSG00000116205","Gene description":"Transcription elongation factor A N-terminal and central domain containing 2","Uniprot":["Q96MN5"],"Chromosome":"1","Position":"54053584-54112519","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"40.6","Spermatocytes":"30.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046918"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA046918":"AB_2679864"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"}},{"Gene":"TCF3","Gene synonym":["bHLHb21","E2A","E47","ITF1","MGC129647","MGC129648","p75","VDIR"],"Ensembl":"ENSG00000071564","Gene description":"Transcription factor 3","Uniprot":["P15923"],"Chromosome":"19","Position":"1609290-1652615","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"55.3","Spermatogonia":"53.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018351","HPA049808","HPA062476"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB018351":"AB_675504","HPA049808":"AB_2680892","HPA062476":"AB_2684775"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.46e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.53e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"}},{"Gene":"TCF7L2","Gene synonym":["TCF-4","TCF4"],"Ensembl":"ENSG00000148737","Gene description":"Transcription factor 7 like 2","Uniprot":["Q9NQB0"],"Chromosome":"10","Position":"112950247-113167678","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"244.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"256.5","Extravillous trophoblasts":"274.3","monocytes":"232.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"244.9"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"intermediate monocyte":"28.9","non-classical monocyte":"86.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"monocytes":"86.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"midbrain":"67.2","thalamus":"86.6"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"midbrain":"146.8","pons":"97.8","thalamus":"164.3"},"Antibody":["CAB013535","HPA038800"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB013535":"AB_2533167","HPA038800":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-3"}},{"Gene":"TCIRG1","Gene synonym":["a3","Atp6i","ATP6N1C","ATP6V0A3","OC-116","OC116","TIRC7"],"Ensembl":"ENSG00000110719","Gene description":"T cell immune regulator 1, ATPase H+ transporting V0 subunit a3","Uniprot":["Q13488"],"Chromosome":"11","Position":"68039025-68050895","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Hydrogen ion transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Osteopetrosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"289.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"114.5","Hofbauer cells":"116.9","Kupffer cells":"111.5","Macrophages":"114.0","monocytes":"158.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038742"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA038742":"AB_10795138"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.50e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.45e-6"}},{"Gene":"TCTA","Gene synonym":[],"Ensembl":"ENSG00000145022","Gene description":"T cell leukemia translocation altered","Uniprot":["P57738"],"Chromosome":"3","Position":"49412206-49416475","Protein class":["Disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007342"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007342":"AB_2202399"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.76e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.00e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-3"}},{"Gene":"TCTN2","Gene synonym":["C12orf38","FLJ12975","JBTS24","MKS8","TECT2"],"Ensembl":"ENSG00000168778","Gene description":"Tectonic family member 2","Uniprot":["Q96GX1"],"Chromosome":"12","Position":"123671110-123708399","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Joubert syndrome","Meckel syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"15.5","Endometrial ciliated cells":"26.3","Respiratory ciliated cells":"20.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039900"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA039900":"AB_10673366"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"}},{"Gene":"TCTN3","Gene synonym":["C10orf61","DKFZP564D116","JBTS18","TECT3"],"Ensembl":"ENSG00000119977","Gene description":"Tectonic family member 3","Uniprot":["Q6NUS6"],"Chromosome":"10","Position":"95659823-95694143","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Joubert syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026987"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4400000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA026987":"AB_10600911"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.77e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"}},{"Gene":"TDGF1","Gene synonym":["CR","CR-1","CRIPTO","Cripto-1"],"Ensembl":"ENSG00000241186","Gene description":"Teratocarcinoma-derived growth factor 1","Uniprot":["P13385"],"Chromosome":"3","Position":"46574534-46582457","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"23.4","lymphoid tissue":"20.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Distal tubular cells":"93.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"testis cancer":"27.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"testis cancer":"66.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebellum":"11.2","pons and medulla":"8.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051928"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA051928":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"TDRD10","Gene synonym":["DKFZp434M202"],"Ensembl":"ENSG00000163239","Gene description":"Tudor domain containing 10","Uniprot":["Q5VZ19"],"Chromosome":"1","Position":"154502219-154548147","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["RNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"55.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"66.5","Late spermatids":"90.7","Spermatocytes":"94.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"5.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"thyroid cancer":"2.1"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Skin - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054327"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA054327":"AB_2682452"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.04e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"}},{"Gene":"TDRKH","Gene synonym":["TDRD2"],"Ensembl":"ENSG00000182134","Gene description":"Tudor and KH domain containing","Uniprot":["Q9Y2W6"],"Chromosome":"1","Position":"151770107-151791416","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","RNA-mediated gene silencing","Spermatogenesis"],"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"30.1","testis":"22.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"19.4","Late spermatids":"62.7","Spermatocytes":"45.0","Spermatogonia":"21.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016419","HPA019625"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA016419":"AB_1857870","HPA019625":"AB_1857871"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.66e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"}},{"Gene":"TECR","Gene synonym":["GPSN2","MRT14","SC2","TER"],"Ensembl":"ENSG00000099797","Gene description":"Trans-2,3-enoyl-CoA reductase","Uniprot":["Q9NZ01"],"Chromosome":"19","Position":"14517085-14565980","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"970.3","Suprabasal keratinocytes":"675.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Liver - Hepatocytes","Skin - Keratinocyte (other)","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029780","HPA056488"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"10000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA029780":"AB_10603348","HPA056488":"AB_2683149"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.60e-4"}},{"Gene":"TECRL","Gene synonym":["DKFZp313B2333","DKFZp313D0829","GPSN2L","SRD5A2L2","TERL"],"Ensembl":"ENSG00000205678","Gene description":"Trans-2,3-enoyl-CoA reductase like","Uniprot":["Q5HYJ1"],"Chromosome":"4","Position":"64275257-64409468","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"heart muscle":"554.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"67","RNA single cell type specific nTPM":{"Cardiomyocytes":"2536.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"98","RNA cell line specific nTPM":{"Rhabdoid":"50.5"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TECTA","Gene synonym":["DFNA12","DFNA8","DFNB21"],"Ensembl":"ENSG00000109927","Gene description":"Tectorin alpha","Uniprot":["O75443"],"Chromosome":"11","Position":"121101243-121191490","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"5.1","Early spermatids":"4.2","Excitatory neurons":"9.7","Inhibitory neurons":"7.0","Late spermatids":"3.6","Oligodendrocyte precursor cells":"4.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Sarcoma":"3.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018870"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018870":"AB_1857879"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"}},{"Gene":"TECTB","Gene synonym":[],"Ensembl":"ENSG00000119913","Gene description":"Tectorin beta","Uniprot":["Q96PL2"],"Chromosome":"10","Position":"112283400-112305038","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"2.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TEDDM1","Gene synonym":["EDDM9","Epdd1","HE9","TMEM45C"],"Ensembl":"ENSG00000203730","Gene description":"Transmembrane epididymal protein 1","Uniprot":["Q5T9Z0"],"Chromosome":"1","Position":"182398117-182400667","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"433","RNA tissue specific nTPM":{"epididymis":"575.8"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-3"}},{"Gene":"TEFM","Gene synonym":["C17orf42","FLJ22729"],"Ensembl":"ENSG00000172171","Gene description":"Transcription elongation factor, mitochondrial","Uniprot":["Q96QE5"],"Chromosome":"17","Position":"30897336-30906238","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023788","HPA053044"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA023788":"AB_1848818","HPA053044":"AB_2682023"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.20e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.64e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-3"}},{"Gene":"TEK","Gene synonym":["CD202b","TIE-2","TIE2","VMCM","VMCM1"],"Ensembl":"ENSG00000120156","Gene description":"TEK receptor tyrosine kinase","Uniprot":["Q02763"],"Chromosome":"9","Position":"27109141-27230174","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Angiogenesis"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Glaucoma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"46.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Adipocytes":"67.9","Endothelial cells":"76.7","Microglial cells":"37.4","Oligodendrocyte precursor cells":"131.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Rhabdoid":"16.9","testis cancer":"18.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Sinusoid Endothelial cells","Lung - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010359","HPA073265"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Centriolar satellite"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":7750000,"Blood concentration - Conc. blood MS [pg\/L]":"13000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"CAB010359":"AB_2203226","HPA073265":"AB_2686592"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.31e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.81e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-3"}},{"Gene":"TENM1","Gene synonym":["ODZ1","ODZ3","TEN-M1","TEN1","TNM"],"Ensembl":"ENSG00000009694","Gene description":"Teneurin transmembrane protein 1","Uniprot":["Q9UKZ4"],"Chromosome":"X","Position":"124375903-124963817","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Stress response","Transcription","Transcription regulation"],"Molecular function":["Neuropeptide","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"23.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"123.9","Inhibitory neurons":"453.2","Oligodendrocyte precursor cells":"416.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"7.0"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"23.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Gallbladder cancer":"40.8"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002848"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA002848":"AB_1079523"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"}},{"Gene":"TENM2","Gene synonym":["KIAA1127","ODZ2","Ten-M2","TEN2"],"Ensembl":"ENSG00000145934","Gene description":"Teneurin transmembrane protein 2","Uniprot":["Q9NT68"],"Chromosome":"5","Position":"167284799-168264157","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Transcription","Transcription regulation"],"Molecular function":["Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"9.8","heart muscle":"35.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"496.9","Cardiomyocytes":"189.7","Excitatory neurons":"697.3","Inhibitory neurons":"944.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"head and neck cancer":"15.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"40.3","Brain cancer":"36.8"},"RNA tissue cell type enrichment":["Kidney - Podocytes","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038018","HPA038420","HPA068691"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"11000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA038018":null,"HPA038420":"AB_10674682","HPA068691":"AB_2686019"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.52e-4"}},{"Gene":"TENM3","Gene synonym":["KIAA1455","ODZ3","Ten-M3","TEN3"],"Ensembl":"ENSG00000218336","Gene description":"Teneurin transmembrane protein 3","Uniprot":["Q9P273"],"Chromosome":"4","Position":"182143987-182803024","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Differentiation"],"Molecular function":null,"Disease involvement":["Disease variant","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"21.8","placenta":"13.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Inhibitory neurons":"621.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Lung - Fibroblast_2","Prostate - Smooth muscle cells","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047043"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA047043":"AB_2679914"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-4"}},{"Gene":"TENM4","Gene synonym":["KIAA1302","ODZ4","Ten-M4","TEN4"],"Ensembl":"ENSG00000149256","Gene description":"Teneurin transmembrane protein 4","Uniprot":["Q6N022"],"Chromosome":"11","Position":"78652829-79441030","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.8","ovary":"16.6","parathyroid gland":"14.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"130.3","Early spermatids":"95.9","Excitatory neurons":"332.6","Inhibitory neurons":"291.1","Microglial cells":"114.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"33.7"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Skeletal muscle - Fibroblasts","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019521","HPA065961"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019521":"AB_2670171","HPA065961":"AB_2685588"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"}},{"Gene":"TEPP","Gene synonym":[],"Ensembl":"ENSG00000159648","Gene description":"Testis, prostate and placenta expressed","Uniprot":["Q6URK8"],"Chromosome":"16","Position":"57976435-57988116","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"testis":"14.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Early spermatids":"280.7","Late spermatids":"467.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"thyroid cancer":"3.2","urothelial cancer":"1.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD8 T-cell":"1.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"1.7"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062092"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062092":"AB_2684679"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"}},{"Gene":"TERT","Gene synonym":["EST2","hEST2","TCS1","TP2","TRT"],"Ensembl":"ENSG00000164362","Gene description":"Telomerase reverse transcriptase","Uniprot":["O14746"],"Chromosome":"5","Position":"1253147-1295068","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["DNA-binding","Nucleotidyltransferase","Ribonucleoprotein","RNA-directed DNA polymerase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dyskeratosis congenita"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"3.4","Spermatocytes":"1.9","Spermatogonia":"3.2","Undifferentiated cells":"1.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054641","HPA065897"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear speckles","Cytosol"],"Antibody RRID":{"HPA054641":"AB_2682554","HPA065897":"AB_2685576"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"}},{"Gene":"TEX10","Gene synonym":["bA208F1.2","FLJ20287","Ipi1"],"Ensembl":"ENSG00000136891","Gene description":"Testis expressed 10","Uniprot":["Q9NXF1"],"Chromosome":"9","Position":"100302077-100352942","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"53.6","Syncytiotrophoblasts":"49.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045434"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA045434":"AB_10965650"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.46e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-3"}},{"Gene":"TEX101","Gene synonym":["CT131","MGC4766","SGRG","SPATA44","TES101RP"],"Ensembl":"ENSG00000131126","Gene description":"Testis expressed 101","Uniprot":["Q9BY14"],"Chromosome":"19","Position":"43401496-43418597","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"117.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Spermatocytes":"960.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"21.5"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"557","RNA blood cell specific nTPM":{"basophil":"55.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"557","RNA blood lineage specific nTPM":{"granulocytes":"55.7"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041915","HPA042513"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041915":"AB_10795268","HPA042513":"AB_10795507"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"}},{"Gene":"TEX2","Gene synonym":["HT008","KIAA1738","TMEM96"],"Ensembl":"ENSG00000136478","Gene description":"Testis expressed 2","Uniprot":["Q8IWB9"],"Chromosome":"17","Position":"64147227-64263260","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"57.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"plasmacytoid DC":"20.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"20.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020648","HPA057116"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA020648":"AB_1857908","HPA057116":"AB_2683341"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.90e-6"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"}},{"Gene":"TEX261","Gene synonym":["MGC32043","TEG-261"],"Ensembl":"ENSG00000144043","Gene description":"Testis expressed 261","Uniprot":["Q6UWH6"],"Chromosome":"2","Position":"70985942-70994873","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016631"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA016631":"AB_2240434"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.17e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.23e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"}},{"Gene":"TEX264","Gene synonym":["FLJ13935","ZSIG11"],"Ensembl":"ENSG00000164081","Gene description":"Testis expressed 264, ER-phagy receptor","Uniprot":["Q9Y6I9"],"Chromosome":"3","Position":"51662693-51704323","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Autophagy","DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"355.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005002","HPA017739","HPA073223"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB005002":"AB_425976","HPA017739":"AB_1857910","HPA073223":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.67e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.95e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"}},{"Gene":"TEX28","Gene synonym":["CXorf2","fTEX"],"Ensembl":"ENSG00000278057","Gene description":"Testis expressed 28","Uniprot":["O15482"],"Chromosome":"X","Position":"154271265-154295853","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"39","RNA tissue specific nTPM":{"testis":"9.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"78","RNA single cell type specific nTPM":{"Early spermatids":"28.7","Late spermatids":"69.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TEX29","Gene synonym":["bA474D23.1","C13orf16","MGC35169"],"Ensembl":"ENSG00000153495","Gene description":"Testis expressed 29","Uniprot":["Q8N6K0"],"Chromosome":"13","Position":"111316184-111344249","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"16.0","testis":"51.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"82","RNA single cell type specific nTPM":{"Early spermatids":"678.4","Late spermatids":"340.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"1.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"}},{"Gene":"TEX38","Gene synonym":["ATPAF1-AS1","C1orf223","LOC374973","THEG4"],"Ensembl":"ENSG00000186118","Gene description":"Testis expressed 38","Uniprot":["Q6PEX7"],"Chromosome":"1","Position":"46668855-46673594","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"416","RNA tissue specific nTPM":{"testis":"388.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"67","RNA single cell type specific nTPM":{"Early spermatids":"2318.2","Late spermatids":"5190.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA073711"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA073711":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"}},{"Gene":"TEX46","Gene synonym":["C1orf234"],"Ensembl":"ENSG00000227868","Gene description":"Testis expressed 46","Uniprot":["H3BTG2"],"Chromosome":"1","Position":"23010834-23015852","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"55","RNA tissue specific nTPM":{"testis":"83.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"2287.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"}},{"Gene":"TEX50","Gene synonym":[],"Ensembl":"ENSG00000232113","Gene description":"Testis expressed 50","Uniprot":["A0A1B0GTY4"],"Chromosome":"1","Position":"173635338-173637130","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"20","RNA tissue specific nTPM":{"testis":"20.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Early spermatids":"270.4","Late spermatids":"79.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TEX51","Gene synonym":[],"Ensembl":"ENSG00000237524","Gene description":"Testis expressed 51","Uniprot":["A0A1B0GUA7"],"Chromosome":"2","Position":"126898864-126902097","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"183","RNA tissue specific nTPM":{"testis":"59.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"23","RNA single cell type specific nTPM":{"Early spermatids":"467.8","Late spermatids":"296.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TFG","Gene synonym":["FLJ36137","SPG57","TF6"],"Ensembl":"ENSG00000114354","Gene description":"Trafficking from ER to golgi regulator","Uniprot":["Q92734"],"Chromosome":"3","Position":"100709295-100748964","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019473","HPA052206"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA019473":"AB_1857936","HPA052206":"AB_2681760"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"}},{"Gene":"TFR2","Gene synonym":["HFE3","TFRC2"],"Ensembl":"ENSG00000106327","Gene description":"Transferrin receptor 2","Uniprot":["Q9UP52"],"Chromosome":"7","Position":"100620416-100642779","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"liver":"346.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatocytes":"347.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"70","RNA cancer specific FPKM":{"liver cancer":"136.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"22","RNA blood cell specific nTPM":{"basophil":"2.5","eosinophil":"1.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"25","RNA blood lineage specific nTPM":{"granulocytes":"2.5"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Leukemia":"23.3"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016255","HPA017171","HPA073125"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"410000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB016255":"AB_628395","HPA017171":null,"HPA073125":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"}},{"Gene":"TFRC","Gene synonym":["CD71","p90","TFR1"],"Ensembl":"ENSG00000072274","Gene description":"Transferrin receptor","Uniprot":["P02786"],"Chromosome":"3","Position":"196027183-196082096","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Endocytosis","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"254.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"455.8","monocytes":"321.5","Syncytiotrophoblasts":"473.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000153","HPA028598"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endosomes","Lysosomes"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1310000000,"Blood concentration - Conc. blood MS [pg\/L]":"38000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Endosomes","Lysosomes"],"Subcellular additional location":null,"Antibody RRID":{"CAB000153":"AB_2533029","HPA028598":"AB_10601599"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.67e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.96e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"}},{"Gene":"TGFA","Gene synonym":[],"Ensembl":"ENSG00000163235","Gene description":"Transforming growth factor alpha","Uniprot":["P01135"],"Chromosome":"2","Position":"70447284-70554193","Protein class":["Cancer-related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor","Mitogen"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"27.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"35.7","Oligodendrocyte precursor cells":"56.8","Oligodendrocytes":"34.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"11.3","eosinophil":"23.8","neutrophil":"23.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"23.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"150.6"},"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042297"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":57900,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042297":"AB_10793878"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.52e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"}},{"Gene":"TGFBR1","Gene synonym":["ACVRLK4","ALK-5","ALK5","ESS1","MSSE","TBR-i","TBRI"],"Ensembl":"ENSG00000106799","Gene description":"Transforming growth factor beta receptor 1","Uniprot":["P36897"],"Chromosome":"9","Position":"99104038-99154192","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Differentiation","Growth regulation"],"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Aortic aneurysm","Craniosynostosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"145.8","Early spermatids":"111.5","Late spermatids":"123.2","Microglial cells":"113.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002441","CAB031481","HPA056473"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002441":"AB_564029","CAB031481":"AB_2202455","HPA056473":"AB_2683144"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"}},{"Gene":"TGFBR2","Gene synonym":["MFS2","TBR-ii","TBRII"],"Ensembl":"ENSG00000163513","Gene description":"Transforming growth factor beta receptor 2","Uniprot":["P37173"],"Chromosome":"3","Position":"30606601-30694142","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Differentiation","Growth regulation"],"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Aortic aneurysm","Cancer-related genes","Craniosynostosis","Disease variant","FDA approved drug targets","Hereditary nonpolyposis colorectal cancer"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"394.6","Alveolar cells type 1":"203.2","Endothelial cells":"391.4","Fibroblasts":"211.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Heart muscle - Macrophages","Kidney - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB073537"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"810000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB073537":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"}},{"Gene":"TGFBR3","Gene synonym":["betaglycan","BGCAN"],"Ensembl":"ENSG00000069702","Gene description":"Transforming growth factor beta receptor 3","Uniprot":["Q03167"],"Chromosome":"1","Position":"91680343-91906335","Protein class":["Cancer-related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"145.0","Endothelial cells":"121.4","Fibroblasts":"170.0","Leydig cells":"146.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"35.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"NK-cells":"16.6","T-cells":"35.2"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Gallbladder cancer":"71.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008257","CAB018971"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB018971":null,"HPA008257":"AB_1080258"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.36e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.84e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.99e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.14e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"}},{"Gene":"TGIF2-RAB5IF","Gene synonym":["TGIF2-C20orf24"],"Ensembl":"ENSG00000259399","Gene description":"TGIF2-RAB5IF readthrough","Uniprot":[],"Chromosome":"20","Position":"36574553-36612384","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076106"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA076106":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"TH","Gene synonym":["DYT5b"],"Ensembl":"ENSG00000180176","Gene description":"Tyrosine hydroxylase","Uniprot":["P07101"],"Chromosome":"11","Position":"2163929-2171815","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Catecholamine biosynthesis","Neurotransmitter biosynthesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Disease variant","Dystonia","FDA approved drug targets","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"69","RNA tissue specific nTPM":{"adrenal gland":"196.6","brain":"270.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Endometrial stromal cells":"9.5","Extravillous trophoblasts":"15.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"urothelial cancer":"4.0"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"midbrain":"192.4","pons":"270.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Brain cancer":"32.5","Neuroblastoma":"44.0"},"RNA tissue cell type enrichment":["Pancreas - Beta cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"178.8"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"20","RNA pig brain regional specific nTPM":{"midbrain":"594.4"},"Antibody":["CAB002522","HPA013768","HPA014010","HPA061003","CAB072340"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002522":"AB_564047","CAB072340":null,"HPA013768":null,"HPA014010":null,"HPA061003":"AB_2630374"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"}},{"Gene":"THADA","Gene synonym":["ARMC13","FLJ21877","GITA","KIAA1767"],"Ensembl":"ENSG00000115970","Gene description":"THADA armadillo repeat containing","Uniprot":["Q6YHU6"],"Chromosome":"2","Position":"43230851-43596038","Protein class":["Disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"72.4","Excitatory neurons":"76.4","Inhibitory neurons":"75.4","Microglial cells":"87.6","Oligodendrocyte precursor cells":"70.8","Oligodendrocytes":"104.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"17.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035191","HPA035192"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035191":"AB_10670290","HPA035192":"AB_2674512"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"}},{"Gene":"THAP4","Gene synonym":["CGI-36","Nb(III)"],"Ensembl":"ENSG00000176946","Gene description":"THAP domain containing 4","Uniprot":["Q8WY91"],"Chromosome":"2","Position":"241584405-241637158","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":null,"Molecular function":["DNA-binding","Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"158.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044982"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA044982":"AB_10959786"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.46e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"THBD","Gene synonym":["CD141"],"Ensembl":"ENSG00000178726","Gene description":"Thrombomodulin","Uniprot":["P07204"],"Chromosome":"20","Position":"23045633-23049672","Protein class":["Candidate cardiovascular disease genes","CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Blood coagulation","Hemostasis"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Hemolytic uremic syndrome","Thrombophilia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"256.4","Endothelial cells":"228.2","Leydig cells":"134.2","Macrophages":"138.7","Peritubular cells":"259.3","Schwann cells":"209.3","Skeletal myocytes":"145.5","Squamous epithelial cells":"244.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"24.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"10.8","granulocytes":"24.6","monocytes":"9.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"94.4","head and neck cancer":"55.0"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Heart muscle - Endothelial cells","Prostate - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002425","HPA002982"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":5550000,"Blood concentration - Conc. blood MS [pg\/L]":"1300000","Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002425":"AB_563497","HPA002982":"AB_1078444"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"}},{"Gene":"THEMIS","Gene synonym":["bA325O24.3","bA325O24.4","C6orf190","C6orf207","FLJ40584","TSEPA"],"Ensembl":"ENSG00000172673","Gene description":"Thymocyte selection associated","Uniprot":["Q8N1K5"],"Chromosome":"6","Position":"127708072-127918631","Protein class":["Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"lymphoid tissue":"32.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"46.3","Microglial cells":"14.6","Serous glandular cells":"10.9","T-cells":"66.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"22","RNA blood cell specific nTPM":{"gdT-cell":"26.7","MAIT T-cell":"34.0","memory CD4 T-cell":"33.5","memory CD8 T-cell":"48.9","naive CD4 T-cell":"30.0","naive CD8 T-cell":"58.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"88","RNA blood lineage specific nTPM":{"T-cells":"58.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"19","RNA cell line specific nTPM":{"Leukemia":"3.6","lymphoma":"3.1","Myeloma":"5.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Kidney - T-cells","Liver - T-cells","Lung - T-cells","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Stomach - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031422","HPA031425"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA031422":"AB_2673874","HPA031425":"AB_10670129"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"}},{"Gene":"THOC1","Gene synonym":["HPR1","P84"],"Ensembl":"ENSG00000079134","Gene description":"THO complex 1","Uniprot":["Q96FV9"],"Chromosome":"18","Position":"214520-268050","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","mRNA processing","mRNA splicing","mRNA transport","Transcription","Transcription regulation","Transport"],"Molecular function":["DNA-binding","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"89.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019096","HPA019687"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA019096":"AB_1857979","HPA019687":"AB_1857980"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.43e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.89e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.80e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.62e-4"}},{"Gene":"THOC2","Gene synonym":["CXorf3","dJ506G2.1","MRX12","MRX35","THO2"],"Ensembl":"ENSG00000125676","Gene description":"THO complex 2","Uniprot":["Q8NI27"],"Chromosome":"X","Position":"123600561-123733056","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing","mRNA transport","Transport"],"Molecular function":["RNA-binding"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047921"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA047921":"AB_10960388"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.77e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"}},{"Gene":"THOP1","Gene synonym":[],"Ensembl":"ENSG00000172009","Gene description":"Thimet oligopeptidase 1","Uniprot":["P52888"],"Chromosome":"19","Position":"2785503-2815807","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"139.9","Paneth cells":"144.7","Proximal enterocytes":"307.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025497","HPA035262"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB025497":null,"HPA035262":"AB_2674541"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.35e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.90e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"}},{"Gene":"THPO","Gene synonym":["MGDF","MPLLG","TPO"],"Ensembl":"ENSG00000090534","Gene description":"Thrombopoietin","Uniprot":["P40225"],"Chromosome":"3","Position":"184371935-184381968","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine","Hormone"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"liver":"35.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"2.2","Hepatocytes":"12.1","Late spermatids":"2.9","Proximal tubular cells":"9.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"8.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Gastric cancer":"1.3","liver cancer":"3.9","lung cancer":"1.4","lymphoma":"3.5","testis cancer":"2.3"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1070000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"}},{"Gene":"THSD1","Gene synonym":["TMTSP"],"Ensembl":"ENSG00000136114","Gene description":"Thrombospondin type 1 domain containing 1","Uniprot":["Q9NS62"],"Chromosome":"13","Position":"52377167-52416373","Protein class":["Disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"18.5","Astrocytes":"24.7","Basal respiratory cells":"13.5","Endothelial cells":"25.4","Microglial cells":"17.3","Spermatocytes":"14.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"12.7"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Colon - Endothelial cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012611","CAB020796","HPA071106"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB020796":null,"HPA012611":"AB_1857990","HPA071106":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"}},{"Gene":"THSD4","Gene synonym":["ADAMTSL6","FLJ13710","FVSY9334","PRO34005"],"Ensembl":"ENSG00000187720","Gene description":"Thrombospondin type 1 domain containing 4","Uniprot":["Q6ZMP0"],"Chromosome":"15","Position":"71096952-71783383","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"103.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"325.4","Microglial cells":"240.8","Squamous epithelial cells":"111.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"18.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Mesothelial cells","Heart muscle - Cardiomyocytes","Kidney - Fibroblasts","Testis - Peritubular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"4","RNA pig brain regional specific nTPM":{"spinal cord":"39.0"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"}},{"Gene":"THSD7A","Gene synonym":["KIAA0960"],"Ensembl":"ENSG00000005108","Gene description":"Thrombospondin type 1 domain containing 7A","Uniprot":["Q9UPZ6"],"Chromosome":"7","Position":"11370365-11832198","Protein class":["Disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Angiogenesis","Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"7.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"145.8","Bipolar cells":"162.8","Horizontal cells":"99.3","Inhibitory neurons":"480.4","Microglial cells":"103.1","Oligodendrocyte precursor cells":"251.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"3.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"54","RNA blood cell specific nTPM":{"basophil":"5.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"54","RNA blood lineage specific nTPM":{"granulocytes":"5.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"10.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Prostate - Fibroblasts","Skeletal muscle - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000923"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6100000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000923":"AB_1080271"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.24e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"}},{"Gene":"THSD7B","Gene synonym":["KIAA1679"],"Ensembl":"ENSG00000144229","Gene description":"Thrombospondin type 1 domain containing 7B","Uniprot":["Q9C0I4"],"Chromosome":"2","Position":"136765545-137677718","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.9","retina":"19.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Inhibitory neurons":"149.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"3.7","Rhabdoid":"2.6"},"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051416","HPA056745"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA051416":"AB_2681477","HPA056745":"AB_2683224"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"}},{"Gene":"THY1","Gene synonym":["CD90"],"Ensembl":"ENSG00000154096","Gene description":"Thy-1 cell surface antigen","Uniprot":["P04216"],"Chromosome":"11","Position":"119415476-119424985","Protein class":["CD markers","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"286.8","smooth muscle":"304.7","urinary bladder":"216.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"149.1","Excitatory neurons":"114.3","Fibroblasts":"173.9","Horizontal cells":"116.6","Inhibitory neurons":"101.6","Leydig cells":"99.8","Muller glia cells":"98.5","Proximal tubular cells":"162.8","Smooth muscle cells":"177.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"436.6","thyroid cancer":"250.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Liver - Hepatic stellate cells","Lung - Fibroblast_2","Skin - Fibroblast_1","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003733","CAB068243","CAB068244"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB068243":"AB_2665687","CAB068244":"AB_2665688","HPA003733":"AB_1846340"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.87e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.40e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"}},{"Gene":"TIE1","Gene synonym":["JTK14","TIE"],"Ensembl":"ENSG00000066056","Gene description":"Tyrosine kinase with immunoglobulin like and EGF like domains 1","Uniprot":["P35590"],"Chromosome":"1","Position":"43300982-43323108","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"126.1","Endothelial cells":"108.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"24","RNA blood cell specific nTPM":{"basophil":"2.1","NK-cell":"2.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"24","RNA blood lineage specific nTPM":{"granulocytes":"2.1","NK-cells":"2.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"12.2","ovarian cancer":"22.4","Sarcoma":"24.1","thyroid cancer":"28.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skin - Endothelial cells","Testis - Endothelial cells","Thyroid - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"87000000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"}},{"Gene":"TIGIT","Gene synonym":["DKFZp667A205","FLJ39873","VSIG9","VSTM3"],"Ensembl":"ENSG00000181847","Gene description":"T cell immunoreceptor with Ig and ITIM domains","Uniprot":["Q495A1"],"Chromosome":"3","Position":"114276913-114310288","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lymphoid tissue":"38.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"NK-cells":"60.8","T-cells":"79.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"195.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"T-cells":"195.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"lymphoma":"4.5","Myeloma":"1.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Prostate - T-cells","Skin - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.43e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.96e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"}},{"Gene":"TIMD4","Gene synonym":["TIM4"],"Ensembl":"ENSG00000145850","Gene description":"T cell immunoglobulin and mucin domain containing 4","Uniprot":["Q96H15"],"Chromosome":"5","Position":"156919292-156963226","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"55.3","testis":"144.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"36","RNA single cell type specific nTPM":{"Early spermatids":"1104.9","Late spermatids":"2002.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"renal cancer":"6.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory CD4 T-cell":"1.3","memory CD8 T-cell":"2.4","naive CD4 T-cell":"1.6","naive CD8 T-cell":"1.6","T-reg":"4.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"T-cells":"4.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Kidney cancer":"9.5","lymphoma":"3.6","Myeloma":"10.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Liver - Kupffer cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015625","CAB026027"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"32000000","Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB026027":null,"HPA015625":"AB_1858018"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.37e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"}},{"Gene":"TIMM17A","Gene synonym":["TIM17","TIM17A"],"Ensembl":"ENSG00000134375","Gene description":"Translocase of inner mitochondrial membrane 17A","Uniprot":["Q99595"],"Chromosome":"1","Position":"201955503-201970664","Protein class":["Cancer-related genes","Predicted membrane proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"311.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010083"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA010083":"AB_10602899"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.98e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"}},{"Gene":"TIMM17B","Gene synonym":["DXS9822","JM3"],"Ensembl":"ENSG00000126768","Gene description":"Translocase of inner mitochondrial membrane 17B","Uniprot":["O60830"],"Chromosome":"X","Position":"48893447-48898143","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029093"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Microtubules"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA029093":"AB_10600913"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.63e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.88e-4"}},{"Gene":"TIMM21","Gene synonym":["C18orf55","HSPC154","TIM21"],"Ensembl":"ENSG00000075336","Gene description":"Translocase of inner mitochondrial membrane 21","Uniprot":["Q9BVV7"],"Chromosome":"18","Position":"74148523-74160531","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Cardiomyocytes":"246.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010587","HPA051543"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010587":"AB_1851244","HPA051543":"AB_2681528"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.22e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.38e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"}},{"Gene":"TIMM22","Gene synonym":["TEX4","TIM22"],"Ensembl":"ENSG00000177370","Gene description":"Translocase of inner mitochondrial membrane 22","Uniprot":["Q9Y584"],"Chromosome":"17","Position":"997129-1003671","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"40","RNA blood cell specific nTPM":{"basophil":"4.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"40","RNA blood lineage specific nTPM":{"granulocytes":"4.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"12.3"},"RNA tissue cell type enrichment":["Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045138"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045138":"AB_10962055"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.42e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.41e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-3"}},{"Gene":"TIMM23","Gene synonym":["TIM23"],"Ensembl":"ENSG00000265354","Gene description":"Translocase of inner mitochondrial membrane 23","Uniprot":["O14925"],"Chromosome":"10","Position":"45972489-46003742","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"108.5","Early spermatids":"116.8","Spermatocytes":"132.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031408"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA031408":"AB_10600828"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.77e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.79e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"}},{"Gene":"TIMM23B","Gene synonym":["bA592B15.7"],"Ensembl":"ENSG00000204152","Gene description":"Translocase of inner mitochondrial membrane 23 homolog B","Uniprot":["Q5SRD1"],"Chromosome":"10","Position":"49942049-49974850","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"38.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"}},{"Gene":"TIMM29","Gene synonym":["C19orf52","TIM29"],"Ensembl":"ENSG00000142444","Gene description":"Translocase of inner mitochondrial membrane 29","Uniprot":["Q9BSF4"],"Chromosome":"19","Position":"10928811-10933535","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"102.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041858"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA041858":"AB_10963429"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.93e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.03e-7"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-3"}},{"Gene":"TIMM50","Gene synonym":["TIM50","TIM50L"],"Ensembl":"ENSG00000105197","Gene description":"Translocase of inner mitochondrial membrane 50","Uniprot":["Q3ZCQ8"],"Chromosome":"19","Position":"39480412-39493785","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":["RNA-binding"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"165.6","Late spermatids":"659.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048843","HPA056448"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA048843":null,"HPA056448":"AB_2683137"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"}},{"Gene":"TIMMDC1","Gene synonym":["C3orf1","FLJ22597"],"Ensembl":"ENSG00000113845","Gene description":"Translocase of inner mitochondrial membrane domain containing 1","Uniprot":["Q9NPL8"],"Chromosome":"3","Position":"119498547-119525090","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053214","HPA055846"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA053214":"AB_2682081","HPA055846":"AB_2682941"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"TK1","Gene synonym":[],"Ensembl":"ENSG00000167900","Gene description":"Thymidine kinase 1","Uniprot":["P04183"],"Chromosome":"17","Position":"78174091-78187233","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA synthesis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"77.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"103.0","Erythroid cells":"111.5","Extravillous trophoblasts":"222.9","Plasma cells":"77.0","Undifferentiated cells":"135.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"34.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"white matter":"3.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004683"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004683":"AB_437067"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.87e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.50e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"}},{"Gene":"TK2","Gene synonym":["SCA31"],"Ensembl":"ENSG00000166548","Gene description":"Thymidine kinase 2","Uniprot":["O00142"],"Chromosome":"16","Position":"66508003-66552544","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["DNA synthesis"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","FDA approved drug targets","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041162"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041162":"AB_10961178"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.18e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"}},{"Gene":"TLCD1","Gene synonym":[],"Ensembl":"ENSG00000160606","Gene description":"TLC domain containing 1","Uniprot":["Q96CP7"],"Chromosome":"17","Position":"28724348-28727935","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"35.5","Extravillous trophoblasts":"39.1","Syncytiotrophoblasts":"40.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"plasmacytoid DC":"21.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"21.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042366"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042366":"AB_10794419"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.28e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.05e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"}},{"Gene":"TLCD2","Gene synonym":[],"Ensembl":"ENSG00000185561","Gene description":"TLC domain containing 2","Uniprot":["A6NGC4"],"Chromosome":"17","Position":"1702816-1710377","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"77.5","Distal enterocytes":"72.8","Proximal enterocytes":"65.7","Skeletal myocytes":"75.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"3.4","neutrophil":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"3.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"14.2"},"Antibody":["HPA046063"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046063":"AB_2679520"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.36e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"}},{"Gene":"TLCD3A","Gene synonym":["CT120","FAM57A","FLJ22282"],"Ensembl":"ENSG00000167695","Gene description":"TLC domain containing 3A","Uniprot":["Q8TBR7"],"Chromosome":"17","Position":"732412-742968","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"71.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"40.5","Suprabasal keratinocytes":"59.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"1.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.53e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"}},{"Gene":"TLCD3B","Gene synonym":["DKFZP434I2117","FAM57B"],"Ensembl":"ENSG00000149926","Gene description":"TLC domain containing 3B","Uniprot":["Q71RH2"],"Chromosome":"16","Position":"30024427-30052978","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism"],"Molecular function":["Transferase"],"Disease involvement":["Cone-rod dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"41.7","retina":"67.9","testis":"104.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"55.4","Cone photoreceptor cells":"322.3","Early spermatids":"111.4","Late spermatids":"74.1","Rod photoreceptor cells":"170.5","Spermatocytes":"65.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"2.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Neuroblastoma":"46.1"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Skeletal muscle - Skeletal myocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"}},{"Gene":"TLCD4","Gene synonym":["FLJ31842","TMEM56"],"Ensembl":"ENSG00000152078","Gene description":"TLC domain containing 4","Uniprot":["Q96MV1"],"Chromosome":"1","Position":"95117355-95197607","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"130.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"97.3","Erythroid cells":"178.1","Hepatocytes":"235.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"13.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Alveolar cells type 2","Skin - Sebaceous gland cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046762"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046762":"AB_2679792"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"}},{"Gene":"TLCD4-RWDD3","Gene synonym":["TMEM56-RWDD3"],"Ensembl":"ENSG00000271092","Gene description":"TLCD4-RWDD3 readthrough","Uniprot":[],"Chromosome":"1","Position":"95117923-95247225","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"8.2","Erythroid cells":"4.3","Excitatory neurons":"3.7","Inhibitory neurons":"4.4","Oligodendrocyte precursor cells":"5.8","Oligodendrocytes":"3.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"}},{"Gene":"TLCD5","Gene synonym":["MGC17839","TMEM136"],"Ensembl":"ENSG00000181264","Gene description":"TLC domain containing 5","Uniprot":["Q6ZRR5"],"Chromosome":"11","Position":"120325296-120333686","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"51.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"89.6","Rod photoreceptor cells":"89.0","Sertoli cells":"49.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"plasmacytoid DC":"2.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"2.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074432"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA074432":"AB_2686689"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.65e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"}},{"Gene":"TLE1","Gene synonym":["ESG","ESG1","GRG1"],"Ensembl":"ENSG00000196781","Gene description":"TLE family member 1, transcriptional corepressor","Uniprot":["Q04724"],"Chromosome":"9","Position":"81583683-81689547","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"394.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011482","HPA071396"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB011482":"AB_443210","HPA071396":"AB_2686392"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.07e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.60e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-1"}},{"Gene":"TLE4","Gene synonym":["E(spl)","ESG","GRG4"],"Ensembl":"ENSG00000106829","Gene description":"TLE family member 4, transcriptional corepressor","Uniprot":["Q04727"],"Chromosome":"9","Position":"79571773-79726882","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"108.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"611.3","Late spermatids":"1387.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"24.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast myoepithelial cells","Prostate - Fibroblasts","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065357"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA065357":"AB_2685479"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.94e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"}},{"Gene":"TLK1","Gene synonym":["KIAA0137","PKU-BETA"],"Ensembl":"ENSG00000198586","Gene description":"Tousled like kinase 1","Uniprot":["Q9UKI8"],"Chromosome":"2","Position":"170990823-171231314","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage"],"Molecular function":["Chromatin regulator","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016043"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA016043":"AB_1858027"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"}},{"Gene":"TLR1","Gene synonym":["CD281","KIAA0012","rsc786"],"Ensembl":"ENSG00000174125","Gene description":"Toll like receptor 1","Uniprot":["Q15399"],"Chromosome":"4","Position":"38790677-38856817","Protein class":["CD markers","Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"34.3","lymphoid tissue":"26.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"17.5","Hofbauer cells":"19.4","Kupffer cells":"24.8","Langerhans cells":"19.6","Macrophages":"35.5","Microglial cells":"28.3","monocytes":"31.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"128.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"128.5","monocytes":"42.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"8.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Lung - Neutrophil_2","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"}},{"Gene":"TLR10","Gene synonym":["CD290"],"Ensembl":"ENSG00000174123","Gene description":"Toll like receptor 10","Uniprot":["Q9BXR5"],"Chromosome":"4","Position":"38772238-38782990","Protein class":["CD markers","Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"47.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"59.4","dendritic cells":"13.2","Microglial cells":"16.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"39.0","naive B-cell":"24.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"39.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lymphoma":"27.2"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Prostate - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001940"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA001940":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.98e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"}},{"Gene":"TLR2","Gene synonym":["CD282","TIL4"],"Ensembl":"ENSG00000137462","Gene description":"Toll like receptor 2","Uniprot":["O60603"],"Chromosome":"4","Position":"153684070-153706260","Protein class":["CD markers","Enzymes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"69.9","lymphoid tissue":"51.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"91.8","Langerhans cells":"49.1","Macrophages":"109.0","monocytes":"207.7","Mucus glandular cells":"68.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"199.6","intermediate monocyte":"178.9","myeloid DC":"121.3","neutrophil":"457.8","non-classical monocyte":"121.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"49","RNA blood lineage specific nTPM":{"dendritic cells":"121.3","granulocytes":"457.8","monocytes":"199.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"14.0","Leukemia":"10.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Kidney - Macrophages","Liver - Neutrophils","Lung - Neutrophil_2","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060231","HPA071546"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA060231":null,"HPA071546":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-3"}},{"Gene":"TLR3","Gene synonym":["CD283"],"Ensembl":"ENSG00000164342","Gene description":"Toll like receptor 3","Uniprot":["O15455"],"Chromosome":"4","Position":"186069155-186088073","Protein class":["CD markers","Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor","RNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"69.0","Schwann cells":"36.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"renal cancer":"10.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"5.5","memory CD8 T-cell":"5.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"2.0","T-cells":"5.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"15.9"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025658"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025658":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.09e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"}},{"Gene":"TLR4","Gene synonym":["ARMD10","CD284","hToll","TLR-4"],"Ensembl":"ENSG00000136869","Gene description":"Toll like receptor 4","Uniprot":["O00206"],"Chromosome":"9","Position":"117704175-117724735","Protein class":["CD markers","Enzymes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":["Age-related macular degeneration","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"49.3","Endothelial cells":"41.5","Hofbauer cells":"73.7","Kupffer cells":"129.6","Macrophages":"89.3","monocytes":"118.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"86.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"dendritic cells":"22.4","granulocytes":"86.8","monocytes":"65.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"11.8"},"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells","Kidney - Endothelial cells","Lung - Neutrophil_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004025","HPA049174"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB004025":null,"HPA049174":"AB_2680662"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.29e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.79e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"}},{"Gene":"TLR5","Gene synonym":["FLJ10052","MGC126430","MGC126431","SLEB1","TIL3"],"Ensembl":"ENSG00000187554","Gene description":"Toll like receptor 5","Uniprot":["O60602"],"Chromosome":"1","Position":"223109404-223143248","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":["Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"20.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Mucus glandular cells":"48.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"classical monocyte":"30.8","intermediate monocyte":"28.1","myeloid DC":"23.4","neutrophil":"25.3","non-classical monocyte":"12.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"23.4","granulocytes":"25.3","monocytes":"30.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009013"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB009013":"AB_2240732"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.95e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"}},{"Gene":"TLR6","Gene synonym":["CD286"],"Ensembl":"ENSG00000174130","Gene description":"Toll like receptor 6","Uniprot":["Q9Y2C9"],"Chromosome":"4","Position":"38823715-38856817","Protein class":["CD markers","Enzymes","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"13.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"14.4","Hofbauer cells":"8.6","Macrophages":"15.3","Microglial cells":"20.1","monocytes":"12.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"13.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"13.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062733"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA062733":"AB_2684853"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"}},{"Gene":"TLR7","Gene synonym":[],"Ensembl":"ENSG00000196664","Gene description":"Toll like receptor 7","Uniprot":["Q9NYK1"],"Chromosome":"X","Position":"12867072-12890361","Protein class":["FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"6.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"9.6","dendritic cells":"37.8","Hofbauer cells":"23.6","Langerhans cells":"8.6","Macrophages":"23.4","Microglial cells":"13.7","monocytes":"13.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"20.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"4.7","Myeloma":"5.5"},"RNA tissue cell type enrichment":["Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059613"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059613":"AB_2684083"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"TLR8","Gene synonym":["CD288"],"Ensembl":"ENSG00000101916","Gene description":"Toll like receptor 8","Uniprot":["Q9NR97"],"Chromosome":"X","Position":"12906620-12923169","Protein class":["CD markers","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"10.7","lymphoid tissue":"16.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Kupffer cells":"55.3","Macrophages":"25.3","monocytes":"43.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"74","RNA blood cell specific nTPM":{"classical monocyte":"16.7","intermediate monocyte":"14.9","myeloid DC":"8.4","neutrophil":"27.6","non-classical monocyte":"15.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"78","RNA blood lineage specific nTPM":{"dendritic cells":"8.4","granulocytes":"27.6","monocytes":"16.7"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skin - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001608"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001608":"AB_1080295"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"}},{"Gene":"TLR9","Gene synonym":["CD289"],"Ensembl":"ENSG00000239732","Gene description":"Toll like receptor 9","Uniprot":["Q9NR96"],"Chromosome":"3","Position":"52221080-52225645","Protein class":["CD markers","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.1","lymphoid tissue":"6.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"3.4","Plasma cells":"3.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"plasmacytoid DC":"166.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"166.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"29","RNA cell line specific nTPM":{"Leukemia":"3.5","lymphoma":"12.1","Myeloma":"5.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-3"}},{"Gene":"TM2D1","Gene synonym":["BBP"],"Ensembl":"ENSG00000162604","Gene description":"TM2 domain containing 1","Uniprot":["Q9BX74"],"Chromosome":"1","Position":"61681046-61725423","Protein class":["Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046058","HPA055621"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA046058":"AB_2679519","HPA055621":"AB_2682865"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"TM2D2","Gene synonym":["BLP1"],"Ensembl":"ENSG00000169490","Gene description":"TM2 domain containing 2","Uniprot":["Q9BX73"],"Chromosome":"8","Position":"38988808-38996824","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"190.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047152","HPA050547"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA047152":"AB_2679957","HPA050547":"AB_2681168"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.49e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.71e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"}},{"Gene":"TM2D3","Gene synonym":["BLP2","FLJ22604"],"Ensembl":"ENSG00000184277","Gene description":"TM2 domain containing 3","Uniprot":["Q9BRN9"],"Chromosome":"15","Position":"101621444-101652391","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054064"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA054064":"AB_2682366"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"}},{"Gene":"TM4SF1","Gene synonym":["L6","M3S1"],"Ensembl":"ENSG00000169908","Gene description":"Transmembrane 4 L six family member 1","Uniprot":["P30408"],"Chromosome":"3","Position":"149369022-149377692","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"1147.7","Ductal cells":"1249.3","Endothelial cells":"1190.6","Exocrine glandular cells":"1144.9","Glandular and luminal cells":"1929.9","Squamous epithelial cells":"951.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002760","HPA002823"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002760":null,"HPA002823":"AB_1079221"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.01e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.43e-6"}},{"Gene":"TM4SF18","Gene synonym":["L6D"],"Ensembl":"ENSG00000163762","Gene description":"Transmembrane 4 L six family member 18","Uniprot":["Q96CE8"],"Chromosome":"3","Position":"149318498-149334414","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"33.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"208.5","Endothelial cells":"159.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"17.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"88.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Liver - Sinusoid Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053639","HPA069378"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA053639":null,"HPA069378":"AB_2686133"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.63e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"}},{"Gene":"TM4SF19","Gene synonym":[],"Ensembl":"ENSG00000145107","Gene description":"Transmembrane 4 L six family member 19","Uniprot":["Q96DZ7"],"Chromosome":"3","Position":"196319342-196338503","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"6.0","testis":"4.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hofbauer cells":"64.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"1.4","head and neck cancer":"3.4","lung cancer":"1.4","melanoma":"1.0","urothelial cancer":"0.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"2.5"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"gdT-cell":"14.8","memory CD8 T-cell":"3.9","naive CD8 T-cell":"4.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"T-cells":"14.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"}},{"Gene":"TM4SF20","Gene synonym":["FLJ22800","TCCE518"],"Ensembl":"ENSG00000168955","Gene description":"Transmembrane 4 L six family member 20","Uniprot":["Q53R12"],"Chromosome":"2","Position":"227362038-227381995","Protein class":["Disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Autism spectrum disorder"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"76","RNA tissue specific nTPM":{"intestine":"266.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Proximal enterocytes":"846.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"colorectal cancer":"5.0","liver cancer":"4.7","pancreatic cancer":"5.5","stomach cancer":"11.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"colorectal cancer":"2.3","Gastric cancer":"1.7","liver cancer":"1.2","lung cancer":"1.3","pancreatic cancer":"1.3"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051838","HPA063184","HPA065531"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane","Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA051838":"AB_2681631","HPA063184":"AB_2684958","HPA065531":"AB_2685506"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TM4SF4","Gene synonym":["il-TMP"],"Ensembl":"ENSG00000169903","Gene description":"Transmembrane 4 L six family member 4","Uniprot":["P48230"],"Chromosome":"3","Position":"149474697-149503394","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"gallbladder":"945.8","intestine":"650.8","liver":"703.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cholangiocytes":"2140.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"liver cancer":"249.4","pancreatic cancer":"130.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"66.4","Gastric cancer":"71.7","liver cancer":"77.5"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046430"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA046430":"AB_2679662"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-1"}},{"Gene":"TM4SF5","Gene synonym":[],"Ensembl":"ENSG00000142484","Gene description":"Transmembrane 4 L six family member 5","Uniprot":["O14894"],"Chromosome":"17","Position":"4771884-4783213","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"174.7","liver":"204.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Enteroendocrine cells":"203.1","Hepatocytes":"240.2","Intestinal goblet cells":"193.7","Paneth cells":"254.8","Proximal enterocytes":"584.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"219.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"18.4","liver cancer":"39.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055674"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA055674":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"}},{"Gene":"TM6SF1","Gene synonym":[],"Ensembl":"ENSG00000136404","Gene description":"Transmembrane 6 superfamily member 1","Uniprot":["Q9BZW5"],"Chromosome":"15","Position":"83107572-83144854","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"47.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"26.1","granulocytes":"32.2","Hofbauer cells":"54.0","Langerhans cells":"61.5","Macrophages":"43.7","Microglial cells":"45.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"76.6","eosinophil":"195.8","neutrophil":"118.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"195.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"10.0","lymphoma":"9.4","Myeloma":"3.4"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Pancreas - Macrophages","Skeletal muscle - Skeletal myocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016051","HPA056857"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016051":"AB_2203924","HPA056857":"AB_2683259"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.79e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"}},{"Gene":"TM6SF2","Gene synonym":["Lpr4"],"Ensembl":"ENSG00000213996","Gene description":"Transmembrane 6 superfamily member 2","Uniprot":["Q9BZW4"],"Chromosome":"19","Position":"19264364-19273391","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Lipid metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"intestine":"75.5","liver":"33.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Proximal enterocytes":"232.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"6.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"1.2"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066026"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066026":"AB_2685598"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"}},{"Gene":"TM7SF2","Gene synonym":["ANG1","DHCR14A","NET47"],"Ensembl":"ENSG00000149809","Gene description":"Transmembrane 7 superfamily member 2","Uniprot":["O76062"],"Chromosome":"11","Position":"65111845-65116384","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"246.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"449.8","Hepatocytes":"183.3","Muller glia cells":"174.2","Suprabasal keratinocytes":"207.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"38.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"100.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Prostate - Prostate glandular cells","Skin - Keratinocyte (granular)","Stomach - Parietal cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030691","HPA072704"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA030691":"AB_10602480","HPA072704":"AB_2686551"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.49e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"}},{"Gene":"TM7SF3","Gene synonym":[],"Ensembl":"ENSG00000064115","Gene description":"Transmembrane 7 superfamily member 3","Uniprot":["Q9NS93"],"Chromosome":"12","Position":"26971579-27014434","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Stress response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"258.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"166.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057640"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA057640":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"}},{"Gene":"TM9SF1","Gene synonym":["HMP70","MP70"],"Ensembl":"ENSG00000100926","Gene description":"Transmembrane 9 superfamily member 1","Uniprot":["O15321"],"Chromosome":"14","Position":"24189149-24195687","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"46.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Macrophages","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059249"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA059249":"AB_2683959"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.94e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.04e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"}},{"Gene":"TM9SF2","Gene synonym":["P76"],"Ensembl":"ENSG00000125304","Gene description":"Transmembrane 9 superfamily member 2","Uniprot":["Q99805"],"Chromosome":"13","Position":"99446311-99564048","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005657"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA005657":"AB_1080303"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.40e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.21e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"}},{"Gene":"TM9SF3","Gene synonym":["SMBP"],"Ensembl":"ENSG00000077147","Gene description":"Transmembrane 9 superfamily member 3","Uniprot":["Q9HD45"],"Chromosome":"10","Position":"96518110-96587452","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039609"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA039609":"AB_10673535"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"}},{"Gene":"TM9SF4","Gene synonym":["dJ836N17.2","KIAA0255"],"Ensembl":"ENSG00000101337","Gene description":"Transmembrane 9 superfamily member 4","Uniprot":["Q92544"],"Chromosome":"20","Position":"32109714-32167258","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064099"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA064099":"AB_2685190"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.37e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"}},{"Gene":"TMBIM1","Gene synonym":["LFG3","PP1201","RECS1"],"Ensembl":"ENSG00000135926","Gene description":"Transmembrane BAX inhibitor motif containing 1","Uniprot":["Q969X1"],"Chromosome":"2","Position":"218274197-218292586","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"275.8","Syncytiotrophoblasts":"303.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012093","HPA070824"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA012093":"AB_1858056","HPA070824":"AB_2686317"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.22e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-1"}},{"Gene":"TMBIM4","Gene synonym":["CGI-119","GAAP","LFG4","S1R","ZPRO"],"Ensembl":"ENSG00000155957","Gene description":"Transmembrane BAX inhibitor motif containing 4","Uniprot":["Q9HC24"],"Chromosome":"12","Position":"66135846-66170072","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077642"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA077642":"AB_2686849"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-3"}},{"Gene":"TMBIM6","Gene synonym":["BAXI1","BI-1","TEGT"],"Ensembl":"ENSG00000139644","Gene description":"Transmembrane BAX inhibitor motif containing 6","Uniprot":["P55061"],"Chromosome":"12","Position":"49707725-49764934","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Autophagy","Unfolded protein response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"1803.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"2156.8","Late spermatids":"2673.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017378"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017378":"AB_2669604"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.54e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.91e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.00e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"TMC1","Gene synonym":["DFNA36","DFNB11","DFNB7"],"Ensembl":"ENSG00000165091","Gene description":"Transmembrane channel like 1","Uniprot":["Q8TDI8"],"Chromosome":"9","Position":"72521608-72838297","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Hearing","Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"1.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"18.7","Cytotrophoblasts":"8.2","Early spermatids":"10.0","Endometrial stromal cells":"6.0","Extravillous trophoblasts":"5.2","Microglial cells":"5.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"1.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"}},{"Gene":"TMC2","Gene synonym":["C20orf145","dJ686C3.3"],"Ensembl":"ENSG00000149488","Gene description":"Transmembrane channel like 2","Uniprot":["Q8TDI7"],"Chromosome":"20","Position":"2536573-2643580","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"1.1","pituitary gland":"1.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Late spermatids":"27.4","Oligodendrocyte precursor cells":"31.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"}},{"Gene":"TMC3","Gene synonym":[],"Ensembl":"ENSG00000188869","Gene description":"Transmembrane channel like 3","Uniprot":["Q7Z5M5"],"Chromosome":"15","Position":"81331088-81374213","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"30","RNA tissue specific nTPM":{"parathyroid gland":"83.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"1.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"0.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040265","HPA040510"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA040265":"AB_10795379","HPA040510":"AB_10796123"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"}},{"Gene":"TMC4","Gene synonym":[],"Ensembl":"ENSG00000167608","Gene description":"Transmembrane channel like 4","Uniprot":[],"Chromosome":"19","Position":"54160108-54173250","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"45.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"132.1","Proximal enterocytes":"218.0","Respiratory ciliated cells":"152.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Eccrine sweat gland cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048635"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA048635":"AB_2680470"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.54e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"}},{"Gene":"TMC5","Gene synonym":["FLJ13593"],"Ensembl":"ENSG00000103534","Gene description":"Transmembrane channel like 5","Uniprot":["Q6UXY8"],"Chromosome":"16","Position":"19410496-19499113","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"53.4","stomach 1":"46.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"183.6","Ionocytes":"362.3","Proximal enterocytes":"356.6","Respiratory ciliated cells":"390.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"31.1","Gastric cancer":"31.6","pancreatic cancer":"27.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Breast - Breast glandular cells","Colon - Colon enterocytes","Lung - Alveolar cells type 2","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040810","HPA042037"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA040810":"AB_10795627","HPA042037":"AB_10804126"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.96e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"}},{"Gene":"TMC6","Gene synonym":["EVER1","EVIN1","LAK-4P","TNRC6C-AS1"],"Ensembl":"ENSG00000141524","Gene description":"Transmembrane channel like 6","Uniprot":["Q7Z403"],"Chromosome":"17","Position":"78107397-78132407","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"110.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"100.8","NK-cells":"101.2","T-cells":"96.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Kupffer cells","Skin - Outer root sheath cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051430"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051430":"AB_2681483"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.82e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.20e-4"}},{"Gene":"TMC7","Gene synonym":["FLJ21240"],"Ensembl":"ENSG00000170537","Gene description":"Transmembrane channel like 7","Uniprot":["Q7Z402"],"Chromosome":"16","Position":"18983934-19063942","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"23.9","testis":"9.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"200.5","Late spermatids":"46.5","Oligodendrocytes":"91.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Skin - Outer root sheath cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029465"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029465":"AB_10600914"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.20e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.64e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.20e-4"}},{"Gene":"TMC8","Gene synonym":["EVER2","EVIN2"],"Ensembl":"ENSG00000167895","Gene description":"Transmembrane channel like 8","Uniprot":["Q8IU68"],"Chromosome":"17","Position":"78130770-78142968","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"91.8","intestine":"54.6","lymphoid tissue":"117.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"52.0","granulocytes":"30.8","Hofbauer cells":"31.4","Langerhans cells":"43.5","monocytes":"38.7","NK-cells":"66.1","T-cells":"70.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Leukemia":"67.0","lymphoma":"48.3","Myeloma":"71.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - T-cells","Prostate - T-cells","Stomach - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047387","HPA054429"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA047387":null,"HPA054429":"AB_2682485"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.45e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.19e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.96e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"}},{"Gene":"TMCC1","Gene synonym":["KIAA0779"],"Ensembl":"ENSG00000172765","Gene description":"Transmembrane and coiled-coil domain family 1","Uniprot":["O94876"],"Chromosome":"3","Position":"129647792-129893606","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"115.5","Excitatory neurons":"203.7","Inhibitory neurons":"196.9","Microglial cells":"124.1","Oligodendrocyte precursor cells":"173.3","Oligodendrocytes":"197.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"9.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"9.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"51.4"},"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053894"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053894":"AB_2682295"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.87e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.77e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"}},{"Gene":"TMCC2","Gene synonym":["FLJ38497","HUCEP11"],"Ensembl":"ENSG00000133069","Gene description":"Transmembrane and coiled-coil domain family 2","Uniprot":["O75069"],"Chromosome":"1","Position":"205227946-205285632","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"88.1","brain":"47.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"33.3","Cone photoreceptor cells":"25.8","Erythroid cells":"102.8","Horizontal cells":"32.7","Oligodendrocytes":"68.9","Rod photoreceptor cells":"36.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"10.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Erythroid cells","Skeletal muscle - Skeletal myocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014254"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014254":"AB_1851326"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"}},{"Gene":"TMCC3","Gene synonym":["KIAA1145"],"Ensembl":"ENSG00000057704","Gene description":"Transmembrane and coiled-coil domain family 3","Uniprot":["Q9ULS5"],"Chromosome":"12","Position":"94567122-94650557","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"36.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"83.4","Distal enterocytes":"54.8","Microglial cells":"68.4","Oligodendrocytes":"113.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"46.9","neutrophil":"69.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"69.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014272"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA014272":"AB_1858059"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.87e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"}},{"Gene":"TMCO1","Gene synonym":["HP10122","TMCC4"],"Ensembl":"ENSG00000143183","Gene description":"Transmembrane and coiled-coil domains 1","Uniprot":["Q9UM00"],"Chromosome":"1","Position":"165724293-165827755","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":["Disease variant","Glaucoma","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054768","HPA078775"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA054768":"AB_2682597","HPA078775":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.17e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"}},{"Gene":"TMCO2","Gene synonym":["dJ39G22.2"],"Ensembl":"ENSG00000188800","Gene description":"Transmembrane and coiled-coil domains 2","Uniprot":["Q7Z6W1"],"Chromosome":"1","Position":"40245947-40251684","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"635","RNA tissue specific nTPM":{"testis":"122.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"56","RNA single cell type specific nTPM":{"Early spermatids":"2056.9","Late spermatids":"1662.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"}},{"Gene":"TMCO3","Gene synonym":["C13orf11","FLJ20623"],"Ensembl":"ENSG00000150403","Gene description":"Transmembrane and coiled-coil domains 3","Uniprot":["Q6UWJ1"],"Chromosome":"13","Position":"113491021-113554590","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"20.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039561","HPA048126"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039561":"AB_2676573","HPA048126":"AB_2680276"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.80e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.10e-4"}},{"Gene":"TMCO4","Gene synonym":["DKFZp686C23231"],"Ensembl":"ENSG00000162542","Gene description":"Transmembrane and coiled-coil domains 4","Uniprot":["Q5TGY1"],"Chromosome":"1","Position":"19682240-19799945","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Prostatic glandular cells":"37.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014601","HPA014620"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA014601":"AB_2204302","HPA014620":"AB_2669051"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.71e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.12e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.64e-4"}},{"Gene":"TMCO5A","Gene synonym":["MGC35118","TMCO5"],"Ensembl":"ENSG00000166069","Gene description":"Transmembrane and coiled-coil domains 5A","Uniprot":["Q8N6Q1"],"Chromosome":"15","Position":"37921939-37967724","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"141","RNA tissue specific nTPM":{"testis":"90.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"4004.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056530","HPA064017"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA056530":"AB_2683167","HPA064017":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-4"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMDD1","Gene synonym":["C12orf81","hCG1648055"],"Ensembl":"ENSG00000284730","Gene description":"Transmembrane and death domain 1","Uniprot":["P0DPE3"],"Chromosome":"12","Position":"51813940-51814926","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"37.7","Late spermatids":"12.7"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMED1","Gene synonym":["Il1rl1l","IL1RL1LG","MGC1270","p24g1","p24gamma1","ST2L"],"Ensembl":"ENSG00000099203","Gene description":"Transmembrane p24 trafficking protein 1","Uniprot":["Q13445"],"Chromosome":"19","Position":"10832067-10836318","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Immunity","Innate immunity","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"117.3","Syncytiotrophoblasts":"149.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018507"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018507":"AB_1858063"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.66e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"}},{"Gene":"TMED10","Gene synonym":["p23","P24(DELTA)","p24d1","p24delta1","TMP21"],"Ensembl":"ENSG00000170348","Gene description":"Transmembrane p24 trafficking protein 10","Uniprot":["P49755"],"Chromosome":"14","Position":"75131469-75176612","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"709.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034442","CAB037251","HPA047139","HPA050539"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB034442":"AB_2204336","CAB037251":"AB_1841216","HPA047139":"AB_2679951","HPA050539":"AB_2681163"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.67e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"}},{"Gene":"TMED2","Gene synonym":["P24A","p24b1","p24beta1","RNP24"],"Ensembl":"ENSG00000086598","Gene description":"Transmembrane p24 trafficking protein 2","Uniprot":["Q15363"],"Chromosome":"12","Position":"123584533-123598582","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"733.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014060"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"82000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA014060":"AB_1856389"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.36e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.35e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"}},{"Gene":"TMED3","Gene synonym":["C15orf22","p24B","p24g4","p24gamma4"],"Ensembl":"ENSG00000166557","Gene description":"Transmembrane p24 trafficking protein 3","Uniprot":["Q9Y3Q3"],"Chromosome":"15","Position":"79311112-79427432","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"409.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"337.4","Serous glandular cells":"656.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049314","HPA076949"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA049314":"AB_2680708","HPA076949":"AB_2686820"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.71e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"}},{"Gene":"TMED4","Gene synonym":["HNLF","p24a3","p24alpha3"],"Ensembl":"ENSG00000158604","Gene description":"Transmembrane p24 trafficking protein 4","Uniprot":["Q7Z7H5"],"Chromosome":"7","Position":"44577894-44582287","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014650"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014650":"AB_1858066"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.37e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.37e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"}},{"Gene":"TMED5","Gene synonym":["CGI-100","p24g2","p24gamma2"],"Ensembl":"ENSG00000117500","Gene description":"Transmembrane p24 trafficking protein 5","Uniprot":["Q9Y3A6"],"Chromosome":"1","Position":"93149742-93180516","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050289"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050289":"AB_2681074"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"}},{"Gene":"TMED6","Gene synonym":["MGC23911","p24g5","p24gamma5"],"Ensembl":"ENSG00000157315","Gene description":"Transmembrane p24 trafficking protein 6","Uniprot":["Q8WW62"],"Chromosome":"16","Position":"69343250-69351786","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"pancreas":"298.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"10.4","Endometrial ciliated cells":"27.6","Enteroendocrine cells":"11.7","Exocrine glandular cells":"19.1","Gastric mucus-secreting cells":"11.3","Pancreatic endocrine cells":"17.2","Proximal tubular cells":"12.2","Respiratory ciliated cells":"21.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Stomach - Chief cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012532"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 20: Airway & Pancreas - Proteolysis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012532":"AB_1858065"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.74e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-3"}},{"Gene":"TMED7","Gene synonym":["CGI-109","FLJ90481","p24g3","p24gamma3"],"Ensembl":"ENSG00000134970","Gene description":"Transmembrane p24 trafficking protein 7","Uniprot":["Q9Y3B3"],"Chromosome":"5","Position":"115613210-115632992","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008960","CAB025883"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025883":null,"HPA008960":"AB_1080280"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"}},{"Gene":"TMED9","Gene synonym":["HSGP25L2G","p24a2","p24alpha2"],"Ensembl":"ENSG00000184840","Gene description":"Transmembrane p24 trafficking protein 9","Uniprot":["Q9BVK6"],"Chromosome":"5","Position":"177592203-177597242","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"1075.4","Syncytiotrophoblasts":"890.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014650"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"36000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014650":"AB_1858066"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.88e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"}},{"Gene":"TMEFF1","Gene synonym":["C9orf2","CT120.1","H7365"],"Ensembl":"ENSG00000241697","Gene description":"Transmembrane protein with EGF like and two follistatin like domains 1","Uniprot":["Q8IYR6"],"Chromosome":"9","Position":"100473149-100577636","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"28.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"1.7","Gastric mucus-secreting cells":"1.2","Schwann cells":"4.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"24.8"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051501"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051501":"AB_2681509"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"}},{"Gene":"TMEFF2","Gene synonym":["CT120.2","HPP1","TENB2","TPEF","TR"],"Ensembl":"ENSG00000144339","Gene description":"Transmembrane protein with EGF like and two follistatin like domains 2","Uniprot":["Q9UIK5"],"Chromosome":"2","Position":"191949043-192194933","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"33.3","prostate":"36.6","seminal vesicle":"13.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"409.3","Inhibitory neurons":"371.8","Oligodendrocyte precursor cells":"201.7","Oligodendrocytes":"1262.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"21","RNA cancer specific FPKM":{"prostate cancer":"57.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"18.6","prostate cancer":"21.2"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015587"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA015587":"AB_1858069"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"}},{"Gene":"TMEM100","Gene synonym":["FLJ10970","FLJ37856"],"Ensembl":"ENSG00000166292","Gene description":"Transmembrane protein 100","Uniprot":["Q9NV29"],"Chromosome":"17","Position":"55719627-55732121","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"192.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"50.4","Basal prostatic cells":"47.9","Endothelial cells":"50.3","Fibroblasts":"31.8","Leydig cells":"38.9","Peritubular cells":"56.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"10.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"ovarian cancer":"68.2","Rhabdoid":"19.1"},"RNA tissue cell type enrichment":["Prostate - Fibroblasts","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055936"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA055936":"AB_2682975"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.67e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"}},{"Gene":"TMEM101","Gene synonym":["FLJ23987","MGC4251"],"Ensembl":"ENSG00000091947","Gene description":"Transmembrane protein 101","Uniprot":["Q96IK0"],"Chromosome":"17","Position":"44011188-44023946","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"230.3","Glandular and luminal cells":"552.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Intercalated cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039739","HPA075651"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA039739":"AB_2676657","HPA075651":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.29e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.10e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.10e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"}},{"Gene":"TMEM104","Gene synonym":["FLJ00021","FLJ20255"],"Ensembl":"ENSG00000109066","Gene description":"Transmembrane protein 104","Uniprot":["Q8NE00"],"Chromosome":"17","Position":"74776499-74839753","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044330"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA044330":"AB_10960543"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.71e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.97e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"}},{"Gene":"TMEM106A","Gene synonym":["MGC20235"],"Ensembl":"ENSG00000184988","Gene description":"Transmembrane protein 106A","Uniprot":["Q96A25"],"Chromosome":"17","Position":"43211835-43220041","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"21.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"34.0","Granulosa cells":"45.4","Hofbauer cells":"42.7","Kupffer cells":"30.0","Langerhans cells":"45.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"26.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"26.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.61e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"}},{"Gene":"TMEM106B","Gene synonym":["FLJ11273","MGC33727"],"Ensembl":"ENSG00000106460","Gene description":"Transmembrane protein 106B","Uniprot":["Q9NUM4"],"Chromosome":"7","Position":"12211270-12243367","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Leukodystrophy","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058342"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endosomes","Lysosomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Endosomes","Lysosomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA058342":"AB_2683684"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"}},{"Gene":"TMEM106C","Gene synonym":["MGC5576"],"Ensembl":"ENSG00000134291","Gene description":"Transmembrane protein 106C","Uniprot":["Q9BVX2"],"Chromosome":"12","Position":"47963569-47968878","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"225.3","Muller glia cells":"272.3","Proximal enterocytes":"394.3","Undifferentiated cells":"216.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047204"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047204":"AB_2679982"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.27e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.62e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"}},{"Gene":"TMEM107","Gene synonym":["JBTS29","MGC10744","MKS13"],"Ensembl":"ENSG00000179029","Gene description":"Transmembrane protein 107","Uniprot":["Q6UX40"],"Chromosome":"17","Position":"8172457-8176399","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Developmental protein"],"Disease involvement":["Ciliopathy","Disease variant","Meckel syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052555","HPA059653"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Midbody ring"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 34: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Midbody ring"],"Antibody RRID":{"HPA052555":"AB_2681870","HPA059653":"AB_2684096"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.39e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"}},{"Gene":"TMEM109","Gene synonym":["MGC5508"],"Ensembl":"ENSG00000110108","Gene description":"Transmembrane protein 109","Uniprot":["Q9BVC6"],"Chromosome":"11","Position":"60914158-60923443","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011785"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nuclear membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA011785":"AB_1858075"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.68e-4"}},{"Gene":"TMEM11","Gene synonym":["C17orf35","PM1","PMI"],"Ensembl":"ENSG00000178307","Gene description":"Transmembrane protein 11","Uniprot":["P17152"],"Chromosome":"17","Position":"21197954-21214176","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"81.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051795","HPA062854"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA051795":"AB_2681612","HPA062854":"AB_2684882"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"}},{"Gene":"TMEM114","Gene synonym":[],"Ensembl":"ENSG00000232258","Gene description":"Transmembrane protein 114","Uniprot":["B3SHH9"],"Chromosome":"16","Position":"8537605-8590193","Protein class":["Disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"seminal vesicle":"19.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Basal prostatic cells":"34.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"298","RNA cell line specific nTPM":{"Bone cancer":"29.8"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hypothalamus":"6.6"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM115","Gene synonym":["PL6"],"Ensembl":"ENSG00000126062","Gene description":"Transmembrane protein 115","Uniprot":["Q12893"],"Chromosome":"3","Position":"50354750-50359521","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"91.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006319","HPA015497"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB006319":"AB_425880","HPA015497":"AB_1858076"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.73e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"}},{"Gene":"TMEM116","Gene synonym":["FLJ90167"],"Ensembl":"ENSG00000198270","Gene description":"Transmembrane protein 116","Uniprot":["Q8NCL8"],"Chromosome":"12","Position":"111931282-112013185","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"59.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"70.2","Spermatocytes":"116.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"19.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Stomach - Parietal cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040720"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Microtubules"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA040720":"AB_10795623"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"}},{"Gene":"TMEM117","Gene synonym":["DKFZp434K2435"],"Ensembl":"ENSG00000139173","Gene description":"Transmembrane protein 117","Uniprot":["Q9H0C3"],"Chromosome":"12","Position":"43835967-44389762","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"63.6","Excitatory neurons":"217.2","Inhibitory neurons":"186.2","Microglial cells":"78.4","Oligodendrocyte precursor cells":"117.9","Oligodendrocytes":"143.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046223"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046223":"AB_10960636"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.94e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-1"}},{"Gene":"TMEM119","Gene synonym":["OBIF"],"Ensembl":"ENSG00000183160","Gene description":"Transmembrane protein 119","Uniprot":["Q4V9L6"],"Chromosome":"12","Position":"108589851-108598320","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Biomineralization","Differentiation","Osteogenesis","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"31.4","Late spermatids":"10.8","Microglial cells":"14.6","Peritubular cells":"25.2","Smooth muscle cells":"13.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"29.9","thyroid cancer":"26.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Breast - Fibroblasts","Heart muscle - Fibroblasts","Kidney - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Fibroblast_1","Testis - Peritubular cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051870","HPA052650"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051870":"AB_2681645","HPA052650":"AB_2681901"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.37e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.06e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"}},{"Gene":"TMEM120A","Gene synonym":["NET29","TMPIT"],"Ensembl":"ENSG00000189077","Gene description":"Transmembrane protein 120A","Uniprot":["Q9BXJ8"],"Chromosome":"7","Position":"75986831-75994656","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"250.9","Late spermatids":"1018.3","Proximal enterocytes":"427.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"223.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"}},{"Gene":"TMEM120B","Gene synonym":[],"Ensembl":"ENSG00000188735","Gene description":"Transmembrane protein 120B","Uniprot":["A0PK00"],"Chromosome":"12","Position":"121712752-121783001","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"97.2","NK-cells":"75.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014066"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA014066":"AB_1845296"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.66e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"}},{"Gene":"TMEM121","Gene synonym":["hole","MGC4659","TMEM121A"],"Ensembl":"ENSG00000184986","Gene description":"Transmembrane protein 121","Uniprot":["Q9BTD3"],"Chromosome":"14","Position":"105526583-105530202","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"27.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"2.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049857"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA049857":"AB_2680917"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.87e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"}},{"Gene":"TMEM121B","Gene synonym":["CECR6"],"Ensembl":"ENSG00000183307","Gene description":"Transmembrane protein 121B","Uniprot":["Q9BXQ6"],"Chromosome":"22","Position":"17116297-17121367","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.7","prostate":"6.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"6.7","Excitatory neurons":"6.8","Late spermatids":"11.6","Oligodendrocyte precursor cells":"3.4","Prostatic glandular cells":"7.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"6.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.1","neutrophil":"1.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"1.6","monocytes":"1.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"3.5","Neuroblastoma":"4.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Colon - Macrophages","Heart muscle - Cardiomyocytes","Kidney - Macrophages","Prostate - Prostate glandular cells","Testis - Late spermatids","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068790"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA068790":"AB_2686036"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.88e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"}},{"Gene":"TMEM123","Gene synonym":["KCT3","PORIMIN"],"Ensembl":"ENSG00000152558","Gene description":"Transmembrane protein 123","Uniprot":["Q8N131"],"Chromosome":"11","Position":"102396332-102470384","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"500.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026001","HPA062862"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"CAB026001":null,"HPA062862":"AB_2732691"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.36e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.66e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"}},{"Gene":"TMEM125","Gene synonym":["MGC17299"],"Ensembl":"ENSG00000179178","Gene description":"Transmembrane protein 125","Uniprot":["Q96AQ2"],"Chromosome":"1","Position":"43269983-43274002","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"75.7","pancreas":"89.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"154.8","Alveolar cells type 2":"171.2","Proximal enterocytes":"172.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Colon - Colon enterocytes","Liver - Cholangiocyte","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Skin - Keratinocyte (granular)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015796"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Midbody","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Midbody","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015796":"AB_1858081"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.11e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.91e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"}},{"Gene":"TMEM126A","Gene synonym":["DKFZp586C1924","OPA7"],"Ensembl":"ENSG00000171202","Gene description":"Transmembrane protein 126A","Uniprot":["Q9H061"],"Chromosome":"11","Position":"85647967-85656547","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"203.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046648"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA046648":"AB_2679737"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.60e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"}},{"Gene":"TMEM126B","Gene synonym":["HT007"],"Ensembl":"ENSG00000171204","Gene description":"Transmembrane protein 126B","Uniprot":["Q8IUX1"],"Chromosome":"11","Position":"85628573-85636539","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014480","HPA019186"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA014480":"AB_1858083","HPA019186":"AB_1858084"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"}},{"Gene":"TMEM127","Gene synonym":["FLJ20507","FLJ22257"],"Ensembl":"ENSG00000135956","Gene description":"Transmembrane protein 127","Uniprot":["O75204"],"Chromosome":"2","Position":"96248514-96265997","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.59e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.69e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"}},{"Gene":"TMEM128","Gene synonym":["MGC13159"],"Ensembl":"ENSG00000132406","Gene description":"Transmembrane protein 128","Uniprot":["Q5BJH2"],"Chromosome":"4","Position":"4235542-4248223","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044809"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044809":"AB_10963539"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"}},{"Gene":"TMEM129","Gene synonym":["D4S2561E"],"Ensembl":"ENSG00000168936","Gene description":"Transmembrane protein 129, E3 ubiquitin ligase","Uniprot":["A0AVI4"],"Chromosome":"4","Position":"1715952-1721358","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway","Unfolded protein response"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.64e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-3"}},{"Gene":"TMEM130","Gene synonym":["DKFZp761L1417","FLJ42643"],"Ensembl":"ENSG00000166448","Gene description":"Transmembrane protein 130","Uniprot":["Q8N3G9"],"Chromosome":"7","Position":"98846488-98870771","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"adrenal gland":"37.1","brain":"141.0","pituitary gland":"100.3","testis":"37.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"44.8","Excitatory neurons":"43.2","Horizontal cells":"14.7","Inhibitory neurons":"52.6","Oligodendrocyte precursor cells":"11.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"9.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"13.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012928"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9400","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA012928":"AB_1858085"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.84e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"}},{"Gene":"TMEM131","Gene synonym":["CC28","KIAA0257","PRO1048","RW1","YR-23"],"Ensembl":"ENSG00000075568","Gene description":"Transmembrane protein 131","Uniprot":["Q92545"],"Chromosome":"2","Position":"97756333-97995948","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017678","HPA017682"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Vesicles","Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA017678":"AB_1858086","HPA017682":"AB_1858087"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"}},{"Gene":"TMEM131L","Gene synonym":["DKFZp586H1322","KIAA0922"],"Ensembl":"ENSG00000121210","Gene description":"Transmembrane 131 like","Uniprot":["A2VDJ0"],"Chromosome":"4","Position":"153466346-153636711","Protein class":["Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"49.4","lymphoid tissue":"48.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"60.7","Inhibitory neurons":"60.4","Late spermatids":"60.4","Oligodendrocyte precursor cells":"65.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Leukemia":"33.6","lymphoma":"52.6"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043472","HPA048443"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA043472":"AB_2678496","HPA048443":"AB_2680395"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.69e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"}},{"Gene":"TMEM132A","Gene synonym":["FLJ20539","GBP","HSPA5BP1"],"Ensembl":"ENSG00000006118","Gene description":"Transmembrane protein 132A","Uniprot":["Q24JP5"],"Chromosome":"11","Position":"60924460-60937159","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"187.8","choroid plexus":"117.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"79.7","Bipolar cells":"79.7","Ductal cells":"85.3","Horizontal cells":"156.4","Muller glia cells":"164.7","Rod photoreceptor cells":"171.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051979","HPA060492"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4100000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA051979":"AB_2681681","HPA060492":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.98e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-3"}},{"Gene":"TMEM132B","Gene synonym":["KIAA1786","KIAA1906"],"Ensembl":"ENSG00000139364","Gene description":"Transmembrane protein 132B","Uniprot":["Q14DG7"],"Chromosome":"12","Position":"125186836-125662377","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"13.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"160.4","Excitatory neurons":"425.8","Inhibitory neurons":"470.3","Oligodendrocyte precursor cells":"257.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"glioma":"3.3"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"amygdala":"5.0","basal ganglia":"9.0","cerebral cortex":"13.1","hippocampal formation":"9.6","white matter":"6.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bone cancer":"7.7"},"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035661","HPA035662"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035661":"AB_10669774","HPA035662":"AB_2674726"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"}},{"Gene":"TMEM132C","Gene synonym":["DKFZp761O2018","PPP1R152"],"Ensembl":"ENSG00000181234","Gene description":"Transmembrane protein 132C","Uniprot":["Q8N3T6"],"Chromosome":"12","Position":"128267403-128707915","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"31.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Inhibitory neurons":"213.4","Microglial cells":"156.0","Oligodendrocyte precursor cells":"556.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"1.6","ovarian cancer":"4.6","testis cancer":"4.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"gdT-cell":"1.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"T-cells":"1.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"2.1","Rhabdoid":"2.5","Sarcoma":"3.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015633","HPA015984"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"78000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA015633":"AB_1858089","HPA015984":"AB_1858088"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-3"}},{"Gene":"TMEM132D","Gene synonym":["KIAA1944","MOLT","PPP1R153"],"Ensembl":"ENSG00000151952","Gene description":"Transmembrane protein 132D","Uniprot":["Q14C87"],"Chromosome":"12","Position":"129071725-129904025","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"5.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"60","RNA single cell type specific nTPM":{"Excitatory neurons":"442.4","Inhibitory neurons":"509.3","Oligodendrocyte precursor cells":"548.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"1.8"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells","Prostate - Prostate glandular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010739"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010739":"AB_2204753"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-4"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM132E","Gene synonym":["DFNB99"],"Ensembl":"ENSG00000181291","Gene description":"Transmembrane protein 132E","Uniprot":["Q6IEE7"],"Chromosome":"17","Position":"34579487-34639318","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"17.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"4.0","Horizontal cells":"9.0","Inhibitory neurons":"6.3","Oligodendrocyte precursor cells":"12.5","Proximal tubular cells":"11.7","Schwann cells":"3.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"7.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"1.8","Sarcoma":"4.0"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070608"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000","Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA070608":"AB_2686286"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"}},{"Gene":"TMEM134","Gene synonym":["FLJ21749"],"Ensembl":"ENSG00000172663","Gene description":"Transmembrane protein 134","Uniprot":["Q9H6X4"],"Chromosome":"11","Position":"67461710-67469272","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043744"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043744":"AB_10794773"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"}},{"Gene":"TMEM135","Gene synonym":["FLJ22104"],"Ensembl":"ENSG00000166575","Gene description":"Transmembrane protein 135","Uniprot":["Q86UB9"],"Chromosome":"11","Position":"87037844-87328824","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"118.0","Excitatory neurons":"98.1","Inhibitory neurons":"91.6","Oligodendrocyte precursor cells":"117.9","Oligodendrocytes":"191.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skin - Endothelial cells","Testis - Sertoli cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056685","HPA069473"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA056685":"AB_2683208","HPA069473":"AB_2686139"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.02e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"}},{"Gene":"TMEM138","Gene synonym":["HSPC196","JBTS16"],"Ensembl":"ENSG00000149483","Gene description":"Transmembrane protein 138","Uniprot":["Q9NPI0"],"Chromosome":"11","Position":"61362344-61369509","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Joubert syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"199.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042373"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA042373":"AB_10793880"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.90e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.12e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-1"}},{"Gene":"TMEM139","Gene synonym":["FLJ90586"],"Ensembl":"ENSG00000178826","Gene description":"Transmembrane protein 139","Uniprot":["Q8IV31"],"Chromosome":"7","Position":"143279957-143288048","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"33.8","kidney":"32.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"37.7","Collecting duct cells":"51.2","Ductal cells":"44.7","Proximal enterocytes":"87.1","Proximal tubular cells":"87.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Liver - Hepatocytes","Skin - Eccrine sweat gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036982","HPA036983"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Focal adhesion sites"],"Antibody RRID":{"HPA036982":"AB_2675413","HPA036983":"AB_10672275"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.66e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.05e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-3"}},{"Gene":"TMEM140","Gene synonym":["FLJ11000"],"Ensembl":"ENSG00000146859","Gene description":"Transmembrane protein 140","Uniprot":["Q9NV12"],"Chromosome":"7","Position":"135148072-135166215","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"87.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"43.7","Schwann cells":"39.3","Syncytiotrophoblasts":"60.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"358.4","eosinophil":"109.1","neutrophil":"429.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"429.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"}},{"Gene":"TMEM143","Gene synonym":["FLJ10922"],"Ensembl":"ENSG00000161558","Gene description":"Transmembrane protein 143","Uniprot":["Q96AN5"],"Chromosome":"19","Position":"48332356-48364059","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"43.6","skeletal muscle":"95.5","tongue":"61.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"24.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014476","HPA058645"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA014476":"AB_1858092","HPA058645":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.53e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"TMEM144","Gene synonym":["FLJ11155"],"Ensembl":"ENSG00000164124","Gene description":"Transmembrane protein 144","Uniprot":["Q7Z5S9"],"Chromosome":"4","Position":"158201604-158255416","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"418.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"938.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"2.1","plasmacytoid DC":"2.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"2.2","monocytes":"1.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063554"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA063554":"AB_2685039"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.89e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.48e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"}},{"Gene":"TMEM145","Gene synonym":["FLJ90805"],"Ensembl":"ENSG00000167619","Gene description":"Transmembrane protein 145","Uniprot":["Q8NBT3"],"Chromosome":"19","Position":"42313309-42325064","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"67.8","pituitary gland":"18.3","retina":"28.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"50.6","Cone photoreceptor cells":"25.8","Excitatory neurons":"26.1","Horizontal cells":"78.8","Inhibitory neurons":"53.1","Rod photoreceptor cells":"28.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"8.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"6.8","neutrophil":"14.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"14.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"22.6"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060462"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA060462":"AB_2684285"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"}},{"Gene":"TMEM147","Gene synonym":["MGC1936","NIFIE14"],"Ensembl":"ENSG00000105677","Gene description":"Transmembrane protein 147","Uniprot":["Q9BVK8"],"Chromosome":"19","Position":"35545600-35547526","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.98e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"}},{"Gene":"TMEM14A","Gene synonym":["C6orf73","PTD011"],"Ensembl":"ENSG00000096092","Gene description":"Transmembrane protein 14A","Uniprot":["Q9Y6G1"],"Chromosome":"6","Position":"52671113-52686588","Protein class":["Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072536"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nucleoplasm","Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA072536":"AB_2686531"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"}},{"Gene":"TMEM14B","Gene synonym":["MGC1223"],"Ensembl":"ENSG00000137210","Gene description":"Transmembrane protein 14B","Uniprot":["Q9NUH8"],"Chromosome":"6","Position":"10747759-10852753","Protein class":["Predicted membrane proteins"],"Biological process":["Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.51e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.35e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.41e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"TMEM14C","Gene synonym":["bA421M1.6","C6orf53","HSPC194","NET26"],"Ensembl":"ENSG00000111843","Gene description":"Transmembrane protein 14C","Uniprot":["Q9P0S9"],"Chromosome":"6","Position":"10722915-10731129","Protein class":["Predicted membrane proteins"],"Biological process":["Heme biosynthesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.66e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"}},{"Gene":"TMEM150A","Gene synonym":["FLJ90024","TM6P1","TMEM150","TTN1"],"Ensembl":"ENSG00000168890","Gene description":"Transmembrane protein 150A","Uniprot":["Q86TG1"],"Chromosome":"2","Position":"85598547-85603196","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"139.5","Early spermatids":"115.6","Late spermatids":"92.7","Proximal tubular cells":"71.0","Syncytiotrophoblasts":"129.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019015"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019015":"AB_2204758"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-3"}},{"Gene":"TMEM150B","Gene synonym":["DRAM3","TMEM224","TTN2"],"Ensembl":"ENSG00000180061","Gene description":"Transmembrane protein 150B","Uniprot":["A6NC51"],"Chromosome":"19","Position":"55312801-55334048","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"64.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Proximal enterocytes":"60.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"11.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"5.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"1.9","monocytes":"5.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"7.7","Gastric cancer":"3.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Proximal tubular cells","Lung - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"}},{"Gene":"TMEM150C","Gene synonym":["FLJ12993","TTN3"],"Ensembl":"ENSG00000249242","Gene description":"Transmembrane protein 150C","Uniprot":["B9EJG8"],"Chromosome":"4","Position":"82483170-82562357","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"134.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"86.0","Granulosa cells":"101.1","Syncytiotrophoblasts":"114.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"23.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"13.6"},"RNA tissue cell type enrichment":["Kidney - Podocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052921"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052921":"AB_2681988"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.87e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.68e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.59e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"}},{"Gene":"TMEM151A","Gene synonym":["MGC33486","TMEM151"],"Ensembl":"ENSG00000179292","Gene description":"Transmembrane protein 151A","Uniprot":["Q8N4L1"],"Chromosome":"11","Position":"66291894-66296664","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"brain":"112.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"11.4","Horizontal cells":"18.6","Inhibitory neurons":"10.8","Oligodendrocytes":"66.1","Thymic epithelial cells":"29.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"4.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041035"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA041035":"AB_10794404"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"}},{"Gene":"TMEM151B","Gene synonym":["bA444E17.5","C6orf137","TMEM193"],"Ensembl":"ENSG00000178233","Gene description":"Transmembrane protein 151B","Uniprot":["Q8IW70"],"Chromosome":"6","Position":"44270450-44307506","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"53.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"26.7","Horizontal cells":"12.8","Inhibitory neurons":"30.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Neuroblastoma":"26.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055167"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055167":"AB_2682723"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"}},{"Gene":"TMEM154","Gene synonym":["FLJ32028"],"Ensembl":"ENSG00000170006","Gene description":"Transmembrane protein 154","Uniprot":["Q6P9G4"],"Chromosome":"4","Position":"152618628-152680012","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"58.3","skin 1":"58.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"107.6","Basal keratinocytes":"83.0","granulocytes":"116.0","monocytes":"85.3","Squamous epithelial cells":"109.2","Suprabasal keratinocytes":"309.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"6.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"403.7","eosinophil":"305.7","neutrophil":"477.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"477.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019184","HPA055411"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA019184":"AB_2670088","HPA055411":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"}},{"Gene":"TMEM156","Gene synonym":["FLJ23235"],"Ensembl":"ENSG00000121895","Gene description":"Transmembrane protein 156","Uniprot":["Q8N614"],"Chromosome":"4","Position":"38966744-39032922","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"26.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"82.4","Microglial cells":"66.6","NK-cells":"28.6","Plasma cells":"92.1","Schwann cells":"23.4","T-cells":"25.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"74.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - T-cells","Prostate - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.09e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"}},{"Gene":"TMEM158","Gene synonym":["p40BBp","RIS1"],"Ensembl":"ENSG00000249992","Gene description":"Transmembrane protein 158","Uniprot":["Q8WZ71"],"Chromosome":"3","Position":"45224466-45226287","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"33.3","endometrium 1":"69.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"20.3","Breast myoepithelial cells":"26.2","Endometrial stromal cells":"61.6","Muller glia cells":"76.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"38.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"56.3"},"RNA tissue cell type enrichment":["Pancreas - Ductal cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"95.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074974"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA074974":"AB_2732274"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.43e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.42e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"}},{"Gene":"TMEM159","Gene synonym":["promethin"],"Ensembl":"ENSG00000011638","Gene description":"Transmembrane protein 159","Uniprot":["Q96B96"],"Chromosome":"16","Position":"21158377-21180616","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"128.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"100.9","Basal squamous epithelial cells":"141.1","Squamous epithelial cells":"125.6","Suprabasal keratinocytes":"127.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatic stellate cells","Skeletal muscle - Skeletal myocytes","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018033","HPA063509"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA018033":"AB_2204762","HPA063509":"AB_2685026"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.11e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"}},{"Gene":"TMEM160","Gene synonym":["FLJ20512"],"Ensembl":"ENSG00000130748","Gene description":"Transmembrane protein 160","Uniprot":["Q9NX00"],"Chromosome":"19","Position":"47045909-47048624","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055904"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055904":"AB_2682965"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"}},{"Gene":"TMEM161A","Gene synonym":["FLJ20422","FLJ39645"],"Ensembl":"ENSG00000064545","Gene description":"Transmembrane protein 161A","Uniprot":["Q9NX61"],"Chromosome":"19","Position":"19119169-19138513","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043365"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043365":"AB_10796793"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.99e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-3"}},{"Gene":"TMEM161B","Gene synonym":["MGC33214"],"Ensembl":"ENSG00000164180","Gene description":"Transmembrane protein 161B","Uniprot":["Q8NDZ6"],"Chromosome":"5","Position":"88189633-88269476","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"56.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044562"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044562":"AB_10794291"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"}},{"Gene":"TMEM163","Gene synonym":["DKFZP566N034","SV31"],"Ensembl":"ENSG00000152128","Gene description":"Transmembrane protein 163","Uniprot":["Q8TC26"],"Chromosome":"2","Position":"134455759-134719000","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"28.3","pancreas":"27.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 2":"52.6","Excitatory neurons":"61.3","Oligodendrocyte precursor cells":"210.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"15.9"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Outer root sheath cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007224"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007224":"AB_2667780"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.94e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.15e-4"}},{"Gene":"TMEM164","Gene synonym":["FLJ22679","RP13-360B22.2"],"Ensembl":"ENSG00000157600","Gene description":"Transmembrane protein 164","Uniprot":["Q5U3C3"],"Chromosome":"X","Position":"110002631-110182734","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"81.9","Distal enterocytes":"44.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"59.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"granulocytes":"59.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038784"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA038784":"AB_10670790"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.17e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.14e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-3"}},{"Gene":"TMEM165","Gene synonym":["GDT1","TMPT27","TPARL"],"Ensembl":"ENSG00000134851","Gene description":"Transmembrane protein 165","Uniprot":["Q9HC07"],"Chromosome":"4","Position":"55395957-55453397","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"964.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038299","HPA062424"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA038299":"AB_10675793","HPA062424":"AB_2732682"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.08e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.18e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"}},{"Gene":"TMEM167A","Gene synonym":["FLJ30508","MGC23909","TMEM167"],"Ensembl":"ENSG00000174695","Gene description":"Transmembrane protein 167A","Uniprot":["Q8TBQ9"],"Chromosome":"5","Position":"83052846-83077863","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"352.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077278"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA077278":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"}},{"Gene":"TMEM167B","Gene synonym":["AD-020","C1orf119","FLJ90710"],"Ensembl":"ENSG00000215717","Gene description":"Transmembrane protein 167B","Uniprot":["Q9NRX6"],"Chromosome":"1","Position":"109090764-109096934","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.86e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"}},{"Gene":"TMEM168","Gene synonym":["DKFZp564C012,FLJ13576"],"Ensembl":"ENSG00000146802","Gene description":"Transmembrane protein 168","Uniprot":["Q9H0V1"],"Chromosome":"7","Position":"112762377-112790423","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020389","HPA077143"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA020389":"AB_1858101","HPA077143":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.07e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"}},{"Gene":"TMEM169","Gene synonym":["FLJ34263"],"Ensembl":"ENSG00000163449","Gene description":"Transmembrane protein 169","Uniprot":["Q96HH4"],"Chromosome":"2","Position":"216081866-216102783","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.0","retina":"3.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"15.6","Cone photoreceptor cells":"19.0","Excitatory neurons":"12.9","Inhibitory neurons":"13.6","Oligodendrocyte precursor cells":"10.6","Oligodendrocytes":"8.8","Rod photoreceptor cells":"11.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"18.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070657","HPA074877"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA070657":"AB_2686293","HPA074877":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"TMEM17","Gene synonym":["FLJ34583"],"Ensembl":"ENSG00000186889","Gene description":"Transmembrane protein 17","Uniprot":["Q86X19"],"Chromosome":"2","Position":"62500218-62511894","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"39.5","Spermatogonia":"20.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018100"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA018100":"AB_2240686"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-6"}},{"Gene":"TMEM170A","Gene synonym":["FLJ37611","TMEM170"],"Ensembl":"ENSG00000166822","Gene description":"Transmembrane protein 170A","Uniprot":["Q8WVE7"],"Chromosome":"16","Position":"75443054-75465497","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.36e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"}},{"Gene":"TMEM170B","Gene synonym":[],"Ensembl":"ENSG00000205269","Gene description":"Transmembrane protein 170B","Uniprot":["Q5T4T1"],"Chromosome":"6","Position":"11537749-11583524","Protein class":["Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"25.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"38.0","dendritic cells":"32.4","Excitatory neurons":"56.5","Inhibitory neurons":"51.1","Kupffer cells":"58.8","Macrophages":"34.2","monocytes":"70.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"12.4"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055134"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA055134":"AB_2682709"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"}},{"Gene":"TMEM171","Gene synonym":["PRP2"],"Ensembl":"ENSG00000157111","Gene description":"Transmembrane protein 171","Uniprot":["Q8WVE6"],"Chromosome":"5","Position":"73120569-73131809","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"35.6","kidney":"10.8","lymphoid tissue":"14.3","stomach 1":"25.4","thyroid gland":"31.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"26.9","Cholangiocytes":"34.6","Distal enterocytes":"87.0","Paneth cells":"54.5","Proximal enterocytes":"46.1","Undifferentiated cells":"47.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"MAIT T-cell":"24.1","memory CD8 T-cell":"8.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"89","RNA blood lineage specific nTPM":{"T-cells":"24.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"24.5"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Stomach - Parietal cells","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"3.7"},"Antibody":["HPA042308"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042308":"AB_10796901"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"}},{"Gene":"TMEM174","Gene synonym":["FLJ31268","MGC13034"],"Ensembl":"ENSG00000164325","Gene description":"Transmembrane protein 174","Uniprot":["Q8WUU8"],"Chromosome":"5","Position":"73173193-73175143","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"309","RNA tissue specific nTPM":{"kidney":"153.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Proximal tubular cells":"118.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"126","RNA cancer specific FPKM":{"renal cancer":"6.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037975"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 69: BICR 18 - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037975":"AB_10672732"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.30e-6"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM175","Gene synonym":["MGC4618"],"Ensembl":"ENSG00000127419","Gene description":"Transmembrane protein 175","Uniprot":["Q9BSA9"],"Chromosome":"4","Position":"932387-958656","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057160"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA057160":"AB_2683356"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.85e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-3"}},{"Gene":"TMEM176A","Gene synonym":["HCA112","MS4B1"],"Ensembl":"ENSG00000002933","Gene description":"Transmembrane protein 176A","Uniprot":["Q96HP8"],"Chromosome":"7","Position":"150800403-150805118","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"377.7","liver":"1170.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"1038.0","Paneth cells":"738.1","Proximal enterocytes":"1334.3","Proximal tubular cells":"883.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"210.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"146.5","intermediate monocyte":"98.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"146.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"colorectal cancer":"34.0","Gastric cancer":"34.6","liver cancer":"13.0","lung cancer":"16.6","Neuroblastoma":"10.8","pancreatic cancer":"17.6","thyroid cancer":"16.0"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008770"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA008770":"AB_2256120"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"}},{"Gene":"TMEM176B","Gene synonym":["LR8","MS4B2"],"Ensembl":"ENSG00000106565","Gene description":"Transmembrane protein 176B","Uniprot":["Q3YBM2"],"Chromosome":"7","Position":"150791285-150801360","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"1656.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"1131.1","Paneth cells":"761.0","Proximal enterocytes":"939.4","Proximal tubular cells":"747.7","Schwann cells":"430.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"537.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"865.5","intermediate monocyte":"586.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"865.5"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"39.4"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047509"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA047509":"AB_2680072"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"}},{"Gene":"TMEM177","Gene synonym":["MGC10993"],"Ensembl":"ENSG00000144120","Gene description":"Transmembrane protein 177","Uniprot":["Q53S58"],"Chromosome":"2","Position":"119679167-119686507","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"34.5","Distal tubular cells":"43.5","Proximal tubular cells":"47.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036689","HPA053816"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA036689":"AB_2675253","HPA053816":"AB_2682272"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"}},{"Gene":"TMEM178A","Gene synonym":["MGC33926","TMEM178"],"Ensembl":"ENSG00000152154","Gene description":"Transmembrane protein 178A","Uniprot":["Q8NBL3"],"Chromosome":"2","Position":"39664982-39717963","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"135.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"38.2","Excitatory neurons":"107.3","Horizontal cells":"32.7","Inhibitory neurons":"106.8","Oligodendrocyte precursor cells":"32.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"endometrial cancer":"10.2","glioma":"13.2","prostate cancer":"19.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Rhabdoid":"18.2","testis cancer":"23.7"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Kidney - Intercalated cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052128"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA052128":"AB_2681738"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"}},{"Gene":"TMEM178B","Gene synonym":["DKFZp547G036"],"Ensembl":"ENSG00000261115","Gene description":"Transmembrane protein 178B","Uniprot":["H3BS89"],"Chromosome":"7","Position":"141074064-141480380","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"11.3","parathyroid gland":"11.9","tongue":"12.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"169.5","Excitatory neurons":"577.0","Inhibitory neurons":"553.2","Oligodendrocyte precursor cells":"293.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"11.7"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Cardiomyocytes","Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048771"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA048771":"AB_2680517"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.10e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"}},{"Gene":"TMEM179","Gene synonym":["C14orf90","FLJ42486","TMEM179A"],"Ensembl":"ENSG00000258986","Gene description":"Transmembrane protein 179","Uniprot":["Q6ZVK1"],"Chromosome":"14","Position":"104474678-104605647","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"31.5","pituitary gland":"88.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"45.4","Excitatory neurons":"11.8","Horizontal cells":"42.3","Inhibitory neurons":"12.0","Oligodendrocyte precursor cells":"7.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"2.7","pancreatic cancer":"3.1","testis cancer":"2.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"23.1","prostate cancer":"18.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002942"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA002942":"AB_1078113"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-6"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"}},{"Gene":"TMEM179B","Gene synonym":[],"Ensembl":"ENSG00000185475","Gene description":"Transmembrane protein 179B","Uniprot":["Q7Z7N9"],"Chromosome":"11","Position":"62787402-62790400","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016585","HPA062068"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA016585":"AB_1844357","HPA062068":"AB_2684676"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"}},{"Gene":"TMEM18","Gene synonym":["DKFZp434C1714","lncND"],"Ensembl":"ENSG00000151353","Gene description":"Transmembrane protein 18","Uniprot":["Q96B42"],"Chromosome":"2","Position":"663877-677406","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transcription"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040233"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA040233":"AB_10794737"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"}},{"Gene":"TMEM181","Gene synonym":["GPR178","KIAA1423"],"Ensembl":"ENSG00000146433","Gene description":"Transmembrane protein 181","Uniprot":["Q9P2C4"],"Chromosome":"6","Position":"158536436-158635428","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040189"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA040189":"AB_10793959"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.26e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"}},{"Gene":"TMEM182","Gene synonym":["FLJ30294"],"Ensembl":"ENSG00000170417","Gene description":"Transmembrane protein 182","Uniprot":["Q6ZP80"],"Chromosome":"2","Position":"102736905-103019900","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Myogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"24","RNA tissue specific nTPM":{"heart muscle":"97.6","skeletal muscle":"150.7","tongue":"127.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Cardiomyocytes":"185.1","Skeletal myocytes":"46.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045861"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA045861":"AB_2679475"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"}},{"Gene":"TMEM183A","Gene synonym":["C1orf37"],"Ensembl":"ENSG00000163444","Gene description":"Transmembrane protein 183A","Uniprot":["Q8IXX5"],"Chromosome":"1","Position":"203007374-203024848","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072607"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cell Junctions"],"Antibody RRID":{"HPA072607":"AB_2686539"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"TMEM184A","Gene synonym":["MGC9712","SDMG1"],"Ensembl":"ENSG00000164855","Gene description":"Transmembrane protein 184A","Uniprot":["Q6ZMB5"],"Chromosome":"7","Position":"1542235-1560821","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"94.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"45.0","Intestinal goblet cells":"36.3","Proximal enterocytes":"53.9","Respiratory ciliated cells":"36.8","Suprabasal keratinocytes":"55.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"1.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"70.5"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053790","HPA071312"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053790":"AB_2682263","HPA071312":"AB_2686387"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.94e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"}},{"Gene":"TMEM184B","Gene synonym":["C22orf5","DKFZP586A1024","FM08","HS5O6A"],"Ensembl":"ENSG00000198792","Gene description":"Transmembrane protein 184B","Uniprot":["Q9Y519"],"Chromosome":"22","Position":"38219291-38273010","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"84.1","Oligodendrocytes":"87.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024076"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA024076":"AB_1858106"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.94e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"}},{"Gene":"TMEM184C","Gene synonym":["FLJ10846","TMEM34"],"Ensembl":"ENSG00000164168","Gene description":"Transmembrane protein 184C","Uniprot":["Q9NVA4"],"Chromosome":"4","Position":"147617386-147672044","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"parathyroid gland":"131.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054013"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA054013":"AB_2682343"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.37e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.31e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-3"}},{"Gene":"TMEM185A","Gene synonym":["CXorf13","FAM11A","FRAXF"],"Ensembl":"ENSG00000269556","Gene description":"Transmembrane protein 185A","Uniprot":["Q8NFB2"],"Chromosome":"X","Position":"149596556-149631912","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048295","HPA071744"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA048295":"AB_2680345","HPA071744":"AB_2686441"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"}},{"Gene":"TMEM185B","Gene synonym":["FAM11B","FLJ20979"],"Ensembl":"ENSG00000226479","Gene description":"Transmembrane protein 185B","Uniprot":["Q9H7F4"],"Chromosome":"2","Position":"120217479-120223400","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048295","HPA071744"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA048295":"AB_2680345","HPA071744":"AB_2686441"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.44e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.96e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.71e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"TMEM186","Gene synonym":["C16orf51","DKFZP564K2062"],"Ensembl":"ENSG00000184857","Gene description":"Transmembrane protein 186","Uniprot":["Q96B77"],"Chromosome":"16","Position":"8780384-8797642","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"95.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018226","HPA063559"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA018226":"AB_1845579","HPA063559":"AB_2685041"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.93e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"}},{"Gene":"TMEM187","Gene synonym":["CXorf12","DXS9878E","ITBA1"],"Ensembl":"ENSG00000177854","Gene description":"Transmembrane protein 187","Uniprot":["Q14656"],"Chromosome":"X","Position":"153972754-153983194","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038134"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038134":"AB_10669517"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.14e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"}},{"Gene":"TMEM19","Gene synonym":["FLJ10936"],"Ensembl":"ENSG00000139291","Gene description":"Transmembrane protein 19","Uniprot":["Q96HH6"],"Chromosome":"12","Position":"71686082-71705047","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"75.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016830"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016830":"AB_1858107"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"}},{"Gene":"TMEM190","Gene synonym":["MDAC1"],"Ensembl":"ENSG00000160472","Gene description":"Transmembrane protein 190","Uniprot":["Q8WZ59"],"Chromosome":"19","Position":"55376826-55378246","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"fallopian tube":"138.1","testis":"57.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"644.4","Endometrial ciliated cells":"338.4","Ionocytes":"184.7","Late spermatids":"194.4","Respiratory ciliated cells":"1284.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"endometrial cancer":"11.5"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"6.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"}},{"Gene":"TMEM191B","Gene synonym":[],"Ensembl":"ENSG00000278558","Gene description":"Transmembrane protein 191B","Uniprot":["P0C7N4"],"Chromosome":"22","Position":"18527802-18530573","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"55","RNA tissue specific nTPM":{"testis":"93.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"47.3","Late spermatids":"85.1","Proximal enterocytes":"21.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"}},{"Gene":"TMEM191C","Gene synonym":[],"Ensembl":"ENSG00000206140","Gene description":"Transmembrane protein 191C","Uniprot":["A6NGB0"],"Chromosome":"22","Position":"21466423-21471269","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"36","RNA tissue specific nTPM":{"testis":"50.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Early spermatids":"421.2","Late spermatids":"861.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"3.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-3"}},{"Gene":"TMEM192","Gene synonym":["FLJ38482"],"Ensembl":"ENSG00000170088","Gene description":"Transmembrane protein 192","Uniprot":["Q8IY95"],"Chromosome":"4","Position":"165070608-165208549","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Liver - Hepatocytes","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014717","HPA024110"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Endosomes","Lysosomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Endosomes","Lysosomes"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA014717":"AB_1844373","HPA024110":"AB_2204898"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.52e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.33e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"}},{"Gene":"TMEM196","Gene synonym":["MGC42090"],"Ensembl":"ENSG00000173452","Gene description":"Transmembrane protein 196","Uniprot":["Q5HYL7"],"Chromosome":"7","Position":"19719315-19773617","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"10.4","retina":"21.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"107.9","Endometrial stromal cells":"98.7","Excitatory neurons":"44.3","Oligodendrocyte precursor cells":"122.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"2.0"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043163"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA043163":"AB_10794772"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM198","Gene synonym":["MGC99813","TMEM198A"],"Ensembl":"ENSG00000188760","Gene description":"Transmembrane protein 198","Uniprot":["Q66K66"],"Chromosome":"2","Position":"219543663-219550595","Protein class":["Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"21.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Enteroendocrine cells":"14.1","Horizontal cells":"18.6","Muller glia cells":"11.7","Proximal enterocytes":"11.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"18.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042385","HPA062897"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 55: Endocrine cells - Hormone signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042385":"AB_2677972","HPA062897":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.89e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"}},{"Gene":"TMEM199","Gene synonym":["C17orf32","MGC45714","VMA12","VPH2"],"Ensembl":"ENSG00000244045","Gene description":"Transmembrane protein 199","Uniprot":["Q8N511"],"Chromosome":"17","Position":"28357642-28363683","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027051"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027051":"AB_10600915"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.55e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.54e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"}},{"Gene":"TMEM200A","Gene synonym":["KIAA1913","TTMC"],"Ensembl":"ENSG00000164484","Gene description":"Transmembrane protein 200A","Uniprot":["Q86VY9"],"Chromosome":"6","Position":"130366017-130443067","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"39.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"24.8","Endometrial stromal cells":"17.6","Enteroendocrine cells":"16.3","Granulosa cells":"50.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"7.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"NK-cell":"4.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"NK-cells":"4.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Lung - Fibroblast_1","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014396"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014396":"AB_2204904"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.92e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"}},{"Gene":"TMEM200B","Gene synonym":["TTMB"],"Ensembl":"ENSG00000253304","Gene description":"Transmembrane protein 200B","Uniprot":["Q69YZ2"],"Chromosome":"1","Position":"29119429-29123903","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"60.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"8.8","Fibroblasts":"7.2","Leydig cells":"13.1","Peritubular cells":"14.2","Sertoli cells":"8.3","Smooth muscle cells":"9.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Liver - Hepatic stellate cells","Testis - Sertoli cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055254"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055254":"AB_2682760"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-3"}},{"Gene":"TMEM200C","Gene synonym":["TTMA"],"Ensembl":"ENSG00000206432","Gene description":"Transmembrane protein 200C","Uniprot":["A6NKL6"],"Chromosome":"18","Position":"5882072-5895955","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"7.7","salivary gland":"5.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"17.9","Inhibitory neurons":"7.8","Mucus glandular cells":"10.7","Oligodendrocyte precursor cells":"16.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Rhabdoid":"9.1"},"RNA tissue cell type enrichment":["Kidney - Podocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047253","HPA050490"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA047253":"AB_2680001","HPA050490":"AB_2681144"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"}},{"Gene":"TMEM201","Gene synonym":["Ima1","NET5","RP13-15M17.2","SAMP1"],"Ensembl":"ENSG00000188807","Gene description":"Transmembrane protein 201","Uniprot":["Q5SNT2"],"Chromosome":"1","Position":"9588911-9614877","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"43.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"17.5","Cone photoreceptor cells":"20.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB039039"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB039039":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.36e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.61e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"}},{"Gene":"TMEM202","Gene synonym":["FLJ27523"],"Ensembl":"ENSG00000187806","Gene description":"Transmembrane protein 202","Uniprot":["A6NGA9"],"Chromosome":"15","Position":"72398302-72408367","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"116","RNA tissue specific nTPM":{"testis":"12.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"45","RNA single cell type specific nTPM":{"Early spermatids":"70.4","Late spermatids":"62.8","Spermatocytes":"53.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"testis cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM203","Gene synonym":["HBEBP1","MGC14327"],"Ensembl":"ENSG00000187713","Gene description":"Transmembrane protein 203","Uniprot":["Q969S6"],"Chromosome":"9","Position":"137204082-137205648","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.78e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.50e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"}},{"Gene":"TMEM204","Gene synonym":["C16orf30","CLP24","FLJ20898"],"Ensembl":"ENSG00000131634","Gene description":"Transmembrane protein 204","Uniprot":["Q9BSN7"],"Chromosome":"16","Position":"1528688-1555580","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Stress response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"190.2","Endothelial cells":"99.3","Fibroblasts":"44.3","Peritubular cells":"65.7","Sertoli cells":"44.2","Smooth muscle cells":"47.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"156.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"156.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014028"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014028":"AB_2204906"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.76e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.89e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"}},{"Gene":"TMEM205","Gene synonym":["MBC3205","UNQ501"],"Ensembl":"ENSG00000105518","Gene description":"Transmembrane protein 205","Uniprot":["Q6UW68"],"Chromosome":"19","Position":"11342776-11346518","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"505.4","Late spermatids":"719.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041504"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoplasm","Nuclear membrane"],"Antibody RRID":{"HPA041504":"AB_10795595"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"}},{"Gene":"TMEM207","Gene synonym":[],"Ensembl":"ENSG00000198398","Gene description":"Transmembrane protein 207","Uniprot":["Q6UWW9"],"Chromosome":"3","Position":"190428655-190449901","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"115","RNA tissue specific nTPM":{"kidney":"17.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"38","RNA single cell type specific nTPM":{"Distal tubular cells":"37.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014332"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014332":"AB_2204907"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM208","Gene synonym":["HSPC171"],"Ensembl":"ENSG00000168701","Gene description":"Transmembrane protein 208","Uniprot":["Q9BTX3"],"Chromosome":"16","Position":"67227103-67229278","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041868","HPA041949"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041868":"AB_10962347","HPA041949":"AB_10959903"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.63e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"}},{"Gene":"TMEM209","Gene synonym":["FLJ14803","NET31"],"Ensembl":"ENSG00000146842","Gene description":"Transmembrane protein 209","Uniprot":["Q96SK2"],"Chromosome":"7","Position":"130164713-130207770","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031678"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Nuclear speckles","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nuclear membrane","Nuclear speckles","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA031678":"AB_10603135"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"}},{"Gene":"TMEM210","Gene synonym":[],"Ensembl":"ENSG00000185863","Gene description":"Transmembrane protein 210","Uniprot":["A6NLX4"],"Chromosome":"9","Position":"137170858-137172056","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"testis":"14.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"82","RNA single cell type specific nTPM":{"Early spermatids":"834.8","Late spermatids":"1858.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"1.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"33","RNA blood cell specific nTPM":{"plasmacytoid DC":"3.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"dendritic cells":"3.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"1.9"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Skin - Eccrine sweat gland cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066907"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066907":"AB_2685747"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-5"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM211","Gene synonym":["bA9F11.1"],"Ensembl":"ENSG00000206069","Gene description":"Transmembrane protein 211","Uniprot":["Q6ICI0"],"Chromosome":"22","Position":"24934954-24946695","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"2.6","salivary gland":"5.8","stomach 1":"3.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"2.1","Breast myoepithelial cells":"1.7","Club cells":"1.6","Ionocytes":"8.2","Salivary duct cells":"4.1","Serous glandular cells":"2.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"4.8","endometrial cancer":"3.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"33","RNA cell line specific nTPM":{"colorectal cancer":"6.4"},"RNA tissue cell type enrichment":["Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066784"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066784":"AB_2685722"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"}},{"Gene":"TMEM212","Gene synonym":["FLJ23172"],"Ensembl":"ENSG00000186329","Gene description":"Transmembrane protein 212","Uniprot":["A6NML5"],"Chromosome":"3","Position":"171843349-171938715","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"15.8","fallopian tube":"30.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Endometrial ciliated cells":"10.5","Respiratory ciliated cells":"28.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045736"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nucleoli fibrillar center","Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA045736":"AB_2679436"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM213","Gene synonym":[],"Ensembl":"ENSG00000214128","Gene description":"Transmembrane protein 213","Uniprot":["A2RRL7"],"Chromosome":"7","Position":"138797952-138838101","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"kidney":"76.0","salivary gland":"52.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"49.2","Distal tubular cells":"164.8","Salivary duct cells":"57.4","Serous glandular cells":"32.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"22","RNA cancer specific FPKM":{"renal cancer":"21.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"2.1","neutrophil":"1.1","NK-cell":"2.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"2.1","NK-cells":"2.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Gastric cancer":"1.6","Sarcoma":"1.5"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells (progenitors)","Kidney - Intercalated cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054059"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054059":"AB_2682361"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.54e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"}},{"Gene":"TMEM214","Gene synonym":["FLJ20254"],"Ensembl":"ENSG00000119777","Gene description":"Transmembrane protein 214","Uniprot":["Q6NUQ4"],"Chromosome":"2","Position":"27032910-27041694","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034551"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum","Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA034551":"AB_10602481"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.96e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.39e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"}},{"Gene":"TMEM215","Gene synonym":[],"Ensembl":"ENSG00000188133","Gene description":"Transmembrane protein 215","Uniprot":["Q68D42"],"Chromosome":"9","Position":"32783540-32789201","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.9","retina":"18.3","testis":"3.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Bipolar cells":"581.7","Late spermatids":"353.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"thyroid cancer":"4.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"thalamus":"6.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063207"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA063207":"AB_2732697"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM216","Gene synonym":["CORS2","HSPC244","JBTS2","MGC13379","MKS2"],"Ensembl":"ENSG00000187049","Gene description":"Transmembrane protein 216","Uniprot":["Q9P0N5"],"Chromosome":"11","Position":"61392360-61398863","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Joubert syndrome","Meckel syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"192.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-3"}},{"Gene":"TMEM217","Gene synonym":["C6orf128","dJ355M6.2"],"Ensembl":"ENSG00000172738","Gene description":"Transmembrane protein 217","Uniprot":["Q8N7C4"],"Chromosome":"6","Position":"37212178-37258155","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"9.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"11.3","Exocrine glandular cells":"15.8","Mucus glandular cells":"27.5","Spermatocytes":"14.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045432","HPA071187"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA045432":"AB_2732519","HPA071187":"AB_2732174"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"}},{"Gene":"TMEM218","Gene synonym":[],"Ensembl":"ENSG00000150433","Gene description":"Transmembrane protein 218","Uniprot":["A2RU14"],"Chromosome":"11","Position":"125096545-125111763","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Joubert syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038489"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038489":"AB_10672748"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.93e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.50e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"}},{"Gene":"TMEM219","Gene synonym":["IGFBP-3R"],"Ensembl":"ENSG00000149932","Gene description":"Transmembrane protein 219","Uniprot":["Q86XT9"],"Chromosome":"16","Position":"29940885-29973050","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"641.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059185"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059185":"AB_2683941"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.79e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"}},{"Gene":"TMEM220","Gene synonym":[],"Ensembl":"ENSG00000187824","Gene description":"Transmembrane protein 220","Uniprot":["Q6QAJ8"],"Chromosome":"17","Position":"10699015-10730023","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"103.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"118.9","Hepatocytes":"186.4","Proximal enterocytes":"567.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.23e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.72e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"}},{"Gene":"TMEM221","Gene synonym":[],"Ensembl":"ENSG00000188051","Gene description":"Transmembrane protein 221","Uniprot":["A6NGB7"],"Chromosome":"19","Position":"17435509-17448668","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"7.9","retina":"9.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Muller glia cells":"45.3","Rod photoreceptor cells":"26.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"3.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041580","HPA062945"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA041580":"AB_10795700","HPA062945":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"TMEM222","Gene synonym":["C1orf160","DKFZP564D0478"],"Ensembl":"ENSG00000186501","Gene description":"Transmembrane protein 222","Uniprot":["Q9H0R3"],"Chromosome":"1","Position":"27322145-27336400","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016579","HPA059374"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA016579":"AB_2669392","HPA059374":"AB_2683995"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"}},{"Gene":"TMEM223","Gene synonym":["MGC3196"],"Ensembl":"ENSG00000168569","Gene description":"Transmembrane protein 223","Uniprot":["A0PJW6"],"Chromosome":"11","Position":"62771629-62792006","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014504"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Nuclear membrane","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA014504":"AB_1853881"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"}},{"Gene":"TMEM225","Gene synonym":["PMP22CD","PPP1R154","SPATA47"],"Ensembl":"ENSG00000204300","Gene description":"Transmembrane protein 225","Uniprot":["Q6GV28"],"Chromosome":"11","Position":"123882920-123885670","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"162","RNA tissue specific nTPM":{"testis":"21.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Early spermatids":"123.4","Late spermatids":"36.2","Spermatocytes":"64.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM225B","Gene synonym":[],"Ensembl":"ENSG00000244219","Gene description":"Transmembrane protein 225B","Uniprot":["P0DP42"],"Chromosome":"7","Position":"99598267-99611045","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"34","RNA tissue specific nTPM":{"testis":"137.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Early spermatids":"431.6","Late spermatids":"150.2","Spermatocytes":"452.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"}},{"Gene":"TMEM229A","Gene synonym":[],"Ensembl":"ENSG00000234224","Gene description":"Transmembrane protein 229A","Uniprot":["B2RXF0"],"Chromosome":"7","Position":"124030921-124033067","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"12.6","intestine":"8.4","testis":"5.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"9.2","Horizontal cells":"5.1","Oligodendrocytes":"10.8","Proximal enterocytes":"10.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"32","RNA cell line specific nTPM":{"Bone cancer":"11.1","Neuroblastoma":"11.1"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056391"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 14: Bone cancer - Transcription","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA056391":"AB_2683114"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-3"}},{"Gene":"TMEM229B","Gene synonym":["C14orf83","FLJ33387"],"Ensembl":"ENSG00000198133","Gene description":"Transmembrane protein 229B","Uniprot":["Q8NBD8"],"Chromosome":"14","Position":"67447084-67533739","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"27.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"28.5","Oligodendrocyte precursor cells":"18.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"12.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"24.0"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046562"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046562":"AB_10960265"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.38e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.21e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.79e-5"}},{"Gene":"TMEM230","Gene synonym":["C20orf30","HSPC274"],"Ensembl":"ENSG00000089063","Gene description":"Transmembrane protein 230","Uniprot":["Q96A57"],"Chromosome":"20","Position":"5068232-5113103","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Parkinson disease","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009078","HPA061421"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA009078":"AB_1078345","HPA061421":"AB_2684513"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"}},{"Gene":"TMEM231","Gene synonym":["ALYE870","FLJ22167","JBTS20","MKS11","PRO1886"],"Ensembl":"ENSG00000205084","Gene description":"Transmembrane protein 231","Uniprot":["Q9H6L2"],"Chromosome":"16","Position":"75536741-75556268","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Joubert syndrome","Meckel syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"fallopian tube":"48.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"110.3","Respiratory ciliated cells":"123.6","Rod photoreceptor cells":"38.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042081"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042081":"AB_10795391"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"}},{"Gene":"TMEM232","Gene synonym":["FLJ43080"],"Ensembl":"ENSG00000186952","Gene description":"Transmembrane protein 232","Uniprot":["C9JQI7"],"Chromosome":"5","Position":"110289233-110738956","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"14.4","testis":"16.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"149.9","Early spermatids":"147.5","Endometrial ciliated cells":"86.7","Excitatory neurons":"255.0","Inhibitory neurons":"171.0","Respiratory ciliated cells":"82.7","Spermatocytes":"72.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049386"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049386":"AB_2680739"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"}},{"Gene":"TMEM233","Gene synonym":["DSPB2","IFITMD2"],"Ensembl":"ENSG00000224982","Gene description":"Transmembrane protein 233","Uniprot":["B4DJY2"],"Chromosome":"12","Position":"119593774-119643075","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"66.6","tongue":"21.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"granulocytes":"67.3","Sertoli cells":"27.6","Skeletal myocytes":"65.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"thyroid cancer":"12.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"6.2","thyroid cancer":"4.5"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047506","HPA075435"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA047506":"AB_10963068","HPA075435":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"}},{"Gene":"TMEM234","Gene synonym":["C1orf91","dJ622L5.7","FLJ90779","RP4-622L5"],"Ensembl":"ENSG00000160055","Gene description":"Transmembrane protein 234","Uniprot":["Q8WY98"],"Chromosome":"1","Position":"32214472-32222359","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"61.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015049"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA015049":"AB_1856409"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.35e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"}},{"Gene":"TMEM235","Gene synonym":[],"Ensembl":"ENSG00000204278","Gene description":"Transmembrane protein 235","Uniprot":["A6NFC5"],"Chromosome":"17","Position":"78231310-78240987","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"107.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"23","RNA single cell type specific nTPM":{"Oligodendrocytes":"101.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"glioma":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053939"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053939":"AB_2682316"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM236","Gene synonym":["bA162I21.2","bA16O1.2","FAM23A","FAM23B"],"Ensembl":"ENSG00000148483","Gene description":"Transmembrane protein 236","Uniprot":["Q5W0B7"],"Chromosome":"10","Position":"17752201-17800868","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"intestine":"33.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"54.8","Enteroendocrine cells":"25.9","Intestinal goblet cells":"32.4","Paneth cells":"29.9","Proximal enterocytes":"92.6","Undifferentiated cells":"15.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"1.7","pancreatic cancer":"0.5","stomach cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"1.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Lung - Macrophages","Prostate - Macrophages","Skin - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045096"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045096":"AB_2732516"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"TMEM237","Gene synonym":["ALS2CR4","JBTS14"],"Ensembl":"ENSG00000155755","Gene description":"Transmembrane protein 237","Uniprot":["Q96Q45"],"Chromosome":"2","Position":"201620184-201643570","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Joubert syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"89.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"134.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052596","HPA054732"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052596":"AB_2681879","HPA054732":"AB_2682587"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.51e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.33e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.96e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"}},{"Gene":"TMEM238","Gene synonym":[],"Ensembl":"ENSG00000233493","Gene description":"Transmembrane protein 238","Uniprot":["C9JI98"],"Chromosome":"19","Position":"55379244-55384292","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"15.9","stomach 1":"16.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"142.6","Alveolar cells type 2":"179.4","Breast myoepithelial cells":"314.3","Prostatic glandular cells":"135.7","Suprabasal keratinocytes":"167.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"52.1","stomach cancer":"48.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.84e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"}},{"Gene":"TMEM238L","Gene synonym":["LINC00675"],"Ensembl":"ENSG00000263429","Gene description":"Transmembrane protein 238 like","Uniprot":[],"Chromosome":"17","Position":"10794913-10804099","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"intestine":"37.5","stomach 1":"45.2","urinary bladder":"21.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"24.6","Gastric mucus-secreting cells":"32.8","Squamous epithelial cells":"7.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"13.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bile duct cancer":"2.6","colorectal cancer":"6.9","Gastric cancer":"2.8"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"}},{"Gene":"TMEM239","Gene synonym":[],"Ensembl":"ENSG00000198326","Gene description":"Transmembrane protein 239","Uniprot":["Q8WW34"],"Chromosome":"20","Position":"2816302-2820284","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"115","RNA tissue specific nTPM":{"testis":"106.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Late spermatids":"84.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM240","Gene synonym":["C1orf70","SCA21"],"Ensembl":"ENSG00000205090","Gene description":"Transmembrane protein 240","Uniprot":["Q5SV17"],"Chromosome":"1","Position":"1534778-1540624","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"18.9","Excitatory neurons":"15.2","Horizontal cells":"34.6","Inhibitory neurons":"14.7","Muller glia cells":"11.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066721"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066721":"AB_2732750"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.52e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"}},{"Gene":"TMEM241","Gene synonym":["C18orf45","FLJ44259","MGC11386"],"Ensembl":"ENSG00000134490","Gene description":"Transmembrane protein 241","Uniprot":["Q24JQ0"],"Chromosome":"18","Position":"23197144-23437961","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"69.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"6.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029489","HPA059922"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA029489":"AB_2673067","HPA059922":"AB_2684164"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.80e-4"}},{"Gene":"TMEM242","Gene synonym":["BM033","C6orf35"],"Ensembl":"ENSG00000215712","Gene description":"Transmembrane protein 242","Uniprot":["Q9NWH2"],"Chromosome":"6","Position":"157289025-157323601","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025764"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA025764":"AB_1845742"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"}},{"Gene":"TMEM243","Gene synonym":["C7orf23","MGC4175","MM-TRAG"],"Ensembl":"ENSG00000135185","Gene description":"Transmembrane protein 243","Uniprot":["Q9BU79"],"Chromosome":"7","Position":"87196160-87220587","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"182.6","Early spermatids":"187.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014918"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014918":"AB_2067447"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.45e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.84e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.13e-4"}},{"Gene":"TMEM244","Gene synonym":["bA174C7.4","C6orf191"],"Ensembl":"ENSG00000203756","Gene description":"Transmembrane protein 244","Uniprot":["Q5VVB8"],"Chromosome":"6","Position":"129831244-129861547","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"39","RNA tissue specific nTPM":{"retina":"64.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"8.0","Cone photoreceptor cells":"25.8","Excitatory neurons":"4.8","Oligodendrocytes":"6.6","Rod photoreceptor cells":"21.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory CD4 T-cell":"1.4","T-reg":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"1.6"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Brain cancer":"4.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 79: Retina - Phototransduction","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM245","Gene synonym":["C9orf5","CG-2"],"Ensembl":"ENSG00000106771","Gene description":"Transmembrane protein 245","Uniprot":["Q9H330"],"Chromosome":"9","Position":"109015135-109119947","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023892"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023892":"AB_1845828"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.46e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"}},{"Gene":"TMEM247","Gene synonym":[],"Ensembl":"ENSG00000284701","Gene description":"Transmembrane protein 247","Uniprot":["A6NEH6"],"Chromosome":"2","Position":"46479565-46484425","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"testis":"21.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Early spermatids":"433.6","Late spermatids":"369.4"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Myeloma":"1.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079482"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA079482":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM248","Gene synonym":["C7orf42","FLJ10099","FLJ13090"],"Ensembl":"ENSG00000106609","Gene description":"Transmembrane protein 248","Uniprot":["Q9NWD8"],"Chromosome":"7","Position":"66921225-66958551","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016495"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA016495":"AB_1848643"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"}},{"Gene":"TMEM249","Gene synonym":["C8orfK29"],"Ensembl":"ENSG00000261587","Gene description":"Transmembrane protein 249","Uniprot":["Q2WGJ8"],"Chromosome":"8","Position":"144352219-144354914","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"54","RNA tissue specific nTPM":{"testis":"27.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"23.6","Late spermatids":"22.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"1.1"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078901"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078901":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"}},{"Gene":"TMEM25","Gene synonym":["FLJ14399"],"Ensembl":"ENSG00000149582","Gene description":"Transmembrane protein 25","Uniprot":["Q86YD3"],"Chromosome":"11","Position":"118531041-118547280","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"140.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012163","HPA051562"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6900000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA012163":"AB_1858112","HPA051562":"AB_2681535"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"}},{"Gene":"TMEM250","Gene synonym":["bA83N9.1","C9orf69"],"Ensembl":"ENSG00000238227","Gene description":"Transmembrane protein 250","Uniprot":["H0YL14"],"Chromosome":"9","Position":"136114581-136118875","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066070"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA066070":"AB_2685608"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"}},{"Gene":"TMEM251","Gene synonym":["C14orf109","DKFZP564F1123"],"Ensembl":"ENSG00000153485","Gene description":"Transmembrane protein 251","Uniprot":["Q8N6I4"],"Chromosome":"14","Position":"93184951-93188463","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"104.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Macrophages","Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048559"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA048559":"AB_2680441"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.14e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.10e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"}},{"Gene":"TMEM252","Gene synonym":["C9orf71","MGC34760"],"Ensembl":"ENSG00000181778","Gene description":"Transmembrane protein 252","Uniprot":["Q8N6L7"],"Chromosome":"9","Position":"68536580-68540883","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"22.0","kidney":"35.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"5.7","Proximal enterocytes":"23.5","Proximal tubular cells":"11.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"renal cancer":"35.7"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.2"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"neutrophil":"4.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"40","RNA blood lineage specific nTPM":{"granulocytes":"4.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"ovarian cancer":"2.3","Uterine cancer":"2.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079457"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA079457":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.75e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"}},{"Gene":"TMEM253","Gene synonym":["C14orf176","C14orf95","NCRNA00220"],"Ensembl":"ENSG00000232070","Gene description":"Transmembrane protein 253","Uniprot":["P0C7T8"],"Chromosome":"14","Position":"21098811-21103724","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"intestine":"97.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Proximal enterocytes":"191.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"2.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052329","HPA065092"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052329":"AB_2681791","HPA065092":"AB_2685420"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"TMEM254","Gene synonym":["bA369J21.6","C10orf57","FLJ13263"],"Ensembl":"ENSG00000133678","Gene description":"Transmembrane protein 254","Uniprot":["Q8TBM7"],"Chromosome":"10","Position":"80078646-80092557","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Prostate - Prostate glandular cells","Skin - Keratinocyte (other)","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029105","HPA072613"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA029105":"AB_2672909","HPA072613":"AB_2732205"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"}},{"Gene":"TMEM255A","Gene synonym":["FAM70A","FLJ20716"],"Ensembl":"ENSG00000125355","Gene description":"Transmembrane protein 255A","Uniprot":["Q5JRV8"],"Chromosome":"X","Position":"120258650-120311556","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"48.7","ovary":"19.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"7.0","Oligodendrocyte precursor cells":"31.3","Schwann cells":"13.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"glioma":"21.3","melanoma":"8.0","renal cancer":"7.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"2.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"2.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"12.9","skin cancer":"9.4"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048470"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA048470":"AB_2680406"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-4"}},{"Gene":"TMEM255B","Gene synonym":["FAM70B","MGC20579"],"Ensembl":"ENSG00000184497","Gene description":"Transmembrane protein 255B","Uniprot":["Q8WV15"],"Chromosome":"13","Position":"113759226-113816995","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"60.9","Endothelial cells":"87.8","granulocytes":"28.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"31.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"31.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043334"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA043334":"AB_10795982"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"}},{"Gene":"TMEM256","Gene synonym":["C17orf61","MGC40107"],"Ensembl":"ENSG00000205544","Gene description":"Transmembrane protein 256","Uniprot":["Q8N2U0"],"Chromosome":"17","Position":"7402975-7404097","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"615.3","Proximal enterocytes":"992.4","Proximal tubular cells":"826.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062732"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA062732":"AB_2684852"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"}},{"Gene":"TMEM258","Gene synonym":["C11orf10","Kud","Kuduk"],"Ensembl":"ENSG00000134825","Gene description":"Transmembrane protein 258","Uniprot":["P61165"],"Chromosome":"11","Position":"61768501-61792802","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044602"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA044602":"AB_10961423"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.37e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"}},{"Gene":"TMEM259","Gene synonym":["ASBABP1","C19orf6","MBRL","MGC4022"],"Ensembl":"ENSG00000182087","Gene description":"Transmembrane protein 259","Uniprot":["Q4ZIN3"],"Chromosome":"19","Position":"1009648-1021179","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042669","HPA054801"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA042669":"AB_10794916","HPA054801":"AB_2682604"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.92e-6"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-3"}},{"Gene":"TMEM26","Gene synonym":["Em:AC068892.1","MGC35010"],"Ensembl":"ENSG00000196932","Gene description":"Transmembrane protein 26","Uniprot":["Q6ZUK4"],"Chromosome":"10","Position":"61406642-61453381","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"8.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"6.5","Early spermatids":"5.5","Endometrial stromal cells":"5.1","Excitatory neurons":"5.2","Inhibitory neurons":"4.7","Late spermatids":"5.0","Sertoli cells":"5.5","Theca cells":"10.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"breast cancer":"2.5","endometrial cancer":"1.0","prostate cancer":"1.8","renal cancer":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"1.5","Rhabdoid":"1.9"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Liver - Kupffer cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"2.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"}},{"Gene":"TMEM260","Gene synonym":["C14orf101","FLJ20392"],"Ensembl":"ENSG00000070269","Gene description":"Transmembrane protein 260","Uniprot":["Q9NX78"],"Chromosome":"14","Position":"56488354-56650606","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"39.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"87.5","Excitatory neurons":"65.7","Oligodendrocyte precursor cells":"66.9","Oligodendrocytes":"100.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003502"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003502":"AB_1078314"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.11e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"}},{"Gene":"TMEM262","Gene synonym":[],"Ensembl":"ENSG00000187066","Gene description":"Transmembrane protein 262","Uniprot":["E9PQX1"],"Chromosome":"11","Position":"65084979-65089375","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"43","RNA tissue specific nTPM":{"testis":"21.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Early spermatids":"214.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"}},{"Gene":"TMEM265","Gene synonym":[],"Ensembl":"ENSG00000281991","Gene description":"Transmembrane protein 265","Uniprot":["A0A087WTH1"],"Chromosome":"16","Position":"30740642-30745196","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"9.5","Excitatory neurons":"5.5","Inhibitory neurons":"5.9","Microglial cells":"5.5","Oligodendrocyte precursor cells":"2.4","Oligodendrocytes":"5.6"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"40.3"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM266","Gene synonym":["C15orf27","FLJ38190"],"Ensembl":"ENSG00000169758","Gene description":"Transmembrane protein 266","Uniprot":["Q2M3C6"],"Chromosome":"15","Position":"76059958-76229121","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"8.4","skeletal muscle":"5.8","tongue":"2.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"17.2","Cytotrophoblasts":"13.5","Excitatory neurons":"22.6","Inhibitory neurons":"24.5","Late spermatids":"20.2","Rod photoreceptor cells":"9.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.3"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"8.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Podocytes"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"cerebellum":"58.7"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"cerebellum":"26.8"},"Antibody":["HPA041921","HPA049425"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041921":"AB_10796789","HPA049425":"AB_2732552"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"}},{"Gene":"TMEM267","Gene synonym":["C5orf28","FLJ21657"],"Ensembl":"ENSG00000151881","Gene description":"Transmembrane protein 267","Uniprot":["Q0VDI3"],"Chromosome":"5","Position":"43444252-43483893","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"thyroid gland":"38.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059946","HPA072991"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA059946":"AB_2684175","HPA072991":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.85e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-3"}},{"Gene":"TMEM268","Gene synonym":["C9orf91","DKFZp547P234","FLJ38045"],"Ensembl":"ENSG00000157693","Gene description":"Transmembrane protein 268","Uniprot":["Q5VZI3"],"Chromosome":"9","Position":"114611206-114646422","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"23.9","Excitatory neurons":"24.6","Prostatic glandular cells":"32.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"4.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017199"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017199":"AB_1845845"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"}},{"Gene":"TMEM269","Gene synonym":[],"Ensembl":"ENSG00000274386","Gene description":"Transmembrane protein 269","Uniprot":["A0A1B0GVZ9"],"Chromosome":"1","Position":"42785007-42816619","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"1.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Late spermatids":"65.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"}},{"Gene":"TMEM270","Gene synonym":["MGC26719","WBSCR28"],"Ensembl":"ENSG00000175877","Gene description":"Transmembrane protein 270","Uniprot":["Q6UE05"],"Chromosome":"7","Position":"73861159-73865890","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"215","RNA tissue specific nTPM":{"testis":"77.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"174","RNA single cell type specific nTPM":{"Early spermatids":"821.9","Late spermatids":"435.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077196"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA077196":"AB_2732334"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"}},{"Gene":"TMEM271","Gene synonym":[],"Ensembl":"ENSG00000273238","Gene description":"Transmembrane protein 271","Uniprot":["A0A286YF58"],"Chromosome":"4","Position":"573880-576295","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"23.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"2.6","Bipolar cells":"5.4","Horizontal cells":"12.2","Suprabasal keratinocytes":"2.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"1.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"2.3","Neuroblastoma":"1.2"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM272","Gene synonym":["FLJ37307","LINC00282","NCRNA00282"],"Ensembl":"ENSG00000281106","Gene description":"Transmembrane protein 272","Uniprot":["A0A1B0GTI8"],"Chromosome":"13","Position":"51813347-51845177","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"15.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"3.4","Late spermatids":"5.9","Melanocytes":"7.0","Oligodendrocyte precursor cells":"17.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"amygdala":"4.2","basal ganglia":"15.9","cerebral cortex":"10.0"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"89","RNA blood cell specific nTPM":{"neutrophil":"40.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"89","RNA blood lineage specific nTPM":{"granulocytes":"40.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"2.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"}},{"Gene":"TMEM273","Gene synonym":["C10orf128","Em:AC084727.5"],"Ensembl":"ENSG00000204161","Gene description":"Transmembrane protein 273","Uniprot":["Q5T292"],"Chromosome":"10","Position":"49154725-49188585","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"43.3","Endothelial cells":"46.1","granulocytes":"50.7","Hofbauer cells":"74.7","Langerhans cells":"40.5","Macrophages":"27.8","NK-cells":"27.5","Oligodendrocytes":"29.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"eosinophil":"269.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"269.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Kidney cancer":"9.2","Leukemia":"19.4","lymphoma":"16.6","Myeloma":"6.6"},"RNA tissue cell type enrichment":["Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058166"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA058166":"AB_2683627"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.86e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"}},{"Gene":"TMEM275","Gene synonym":[],"Ensembl":"ENSG00000282881","Gene description":"Transmembrane protein 275","Uniprot":["A0A0U1RQS6"],"Chromosome":"1","Position":"46532166-46543969","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"2.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"23.3"},"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"amygdala":"1.2","basal ganglia":"1.6","hypothalamus":"1.2"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM30A","Gene synonym":["C6orf67","CDC50A","FLJ10856"],"Ensembl":"ENSG00000112697","Gene description":"Transmembrane protein 30A","Uniprot":["Q9NV96"],"Chromosome":"6","Position":"75252924-75284948","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014561"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014561":"AB_10601823"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"}},{"Gene":"TMEM30B","Gene synonym":["CDC50B"],"Ensembl":"ENSG00000182107","Gene description":"Transmembrane protein 30B","Uniprot":["Q3MIR4"],"Chromosome":"14","Position":"61277370-61281761","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043162"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043162":"AB_10796688"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.89e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"}},{"Gene":"TMEM31","Gene synonym":["MGC39655"],"Ensembl":"ENSG00000179363","Gene description":"Transmembrane protein 31","Uniprot":["Q5JXX7"],"Chromosome":"X","Position":"103710909-103714032","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"testis":"110.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Late spermatids":"3503.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052760"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA052760":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"}},{"Gene":"TMEM33","Gene synonym":["FLJ10525","Pom33"],"Ensembl":"ENSG00000109133","Gene description":"Transmembrane protein 33","Uniprot":["P57088"],"Chromosome":"4","Position":"41935129-41960803","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"169.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075863"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA075863":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"}},{"Gene":"TMEM35A","Gene synonym":["FLJ14084","NACHO","TMEM35","TUF-1"],"Ensembl":"ENSG00000126950","Gene description":"Transmembrane protein 35A","Uniprot":["Q53FP2"],"Chromosome":"X","Position":"101078879-101096367","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"71.9","intestine":"36.8","seminal vesicle":"50.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"21.4","Excitatory neurons":"14.8","Horizontal cells":"16.7","Inhibitory neurons":"24.1","Oligodendrocyte precursor cells":"12.5","Peritubular cells":"20.3","Theca cells":"26.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"6.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"13.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048583"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Vesicles","Focal adhesion sites","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Vesicles"],"Subcellular additional location":["Focal adhesion sites","Cytosol"],"Antibody RRID":{"HPA048583":"AB_2680451"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"}},{"Gene":"TMEM35B","Gene synonym":["ZMYM6NB"],"Ensembl":"ENSG00000243749","Gene description":"Transmembrane protein 35B","Uniprot":["Q8NCS4"],"Chromosome":"1","Position":"34981535-34985353","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"19.3","Fibroblasts":"12.6","Gastric mucus-secreting cells":"10.1","Microglial cells":"10.9","Schwann cells":"32.5","T-cells":"12.8","Thymic epithelial cells":"18.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Heart muscle - Fibroblasts","Lung - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051024"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 5: Breast - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA051024":"AB_2681316"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"TMEM37","Gene synonym":["PR","PR1"],"Ensembl":"ENSG00000171227","Gene description":"Transmembrane protein 37","Uniprot":["Q8WXS4"],"Chromosome":"2","Position":"119429901-119438504","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"101.1","liver":"100.0","parathyroid gland":"124.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"178.8","Muller glia cells":"134.0","Proximal enterocytes":"538.7","Proximal tubular cells":"175.5","Syncytiotrophoblasts":"132.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"57.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"30.6"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053794"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA053794":"AB_2682265"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"}},{"Gene":"TMEM38A","Gene synonym":["MGC3169","TRIC-A"],"Ensembl":"ENSG00000072954","Gene description":"Transmembrane protein 38A","Uniprot":["Q9H6F2"],"Chromosome":"19","Position":"16661139-16690023","Protein class":["Predicted membrane proteins"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"skeletal muscle":"581.3","tongue":"260.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"134.4","Skeletal myocytes":"263.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"36.9","eosinophil":"12.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"36.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Stomach - Gastric mucous cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048100","HPA050463"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA048100":null,"HPA050463":"AB_2681137"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.78e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.96e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.99e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"}},{"Gene":"TMEM38B","Gene synonym":["bA219P18.1","C9orf87","D4Ertd89e","FLJ10493","TRIC-B"],"Ensembl":"ENSG00000095209","Gene description":"Transmembrane protein 38B","Uniprot":["Q9NVV0"],"Chromosome":"9","Position":"105694541-105776629","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Ion channel","Potassium channel"],"Disease involvement":["Osteogenesis imperfecta"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"77.4","tongue":"62.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"250.7","Late spermatids":"508.7","Spermatocytes":"145.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Endothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018465"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA018465":"AB_1858116"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.96e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"}},{"Gene":"TMEM39A","Gene synonym":["FLJ10902","SUSR2"],"Ensembl":"ENSG00000176142","Gene description":"Transmembrane protein 39A","Uniprot":["Q9NV64"],"Chromosome":"3","Position":"119428949-119468830","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"66.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039140"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA039140":"AB_10673303"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.00e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"}},{"Gene":"TMEM39B","Gene synonym":["FLJ10315"],"Ensembl":"ENSG00000121775","Gene description":"Transmembrane protein 39B","Uniprot":["Q9GZU3"],"Chromosome":"1","Position":"32072031-32102866","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"43.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040191","HPA040224"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA040191":"AB_10805706","HPA040224":"AB_10795274"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.00e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.82e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.11e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"}},{"Gene":"TMEM40","Gene synonym":["FLJ11036"],"Ensembl":"ENSG00000088726","Gene description":"Transmembrane protein 40","Uniprot":["Q8WWA1"],"Chromosome":"3","Position":"12733528-12769457","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"219.8","skin 1":"64.7","vagina":"80.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"338.0","Syncytiotrophoblasts":"812.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"13.3","urothelial cancer":"12.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"6.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"6.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"62.3","head and neck cancer":"48.8"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Prostate - Urothelial cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044165","HPA073122"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2500000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA044165":"AB_10961279","HPA073122":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"}},{"Gene":"TMEM41A","Gene synonym":["MGC15397"],"Ensembl":"ENSG00000163900","Gene description":"Transmembrane protein 41A","Uniprot":["Q96HV5"],"Chromosome":"3","Position":"185476496-185499057","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"192.4","Squamous epithelial cells":"122.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059101","HPA059790"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA059101":"AB_2683905","HPA059790":"AB_2684125"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.70e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.72e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"}},{"Gene":"TMEM41B","Gene synonym":["KIAA0033"],"Ensembl":"ENSG00000166471","Gene description":"Transmembrane protein 41B","Uniprot":["Q5BJD5"],"Chromosome":"11","Position":"9280654-9314636","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Autophagy","Host-virus interaction","Lipid transport","Neurogenesis","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014946"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Peroxisomes"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Peroxisomes"],"Subcellular additional location":null,"Antibody RRID":{"HPA014946":"AB_2205037"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.18e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"}},{"Gene":"TMEM42","Gene synonym":["MGC29956"],"Ensembl":"ENSG00000169964","Gene description":"Transmembrane protein 42","Uniprot":["Q69YG0"],"Chromosome":"3","Position":"44861904-44865670","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"66.7","Late spermatids":"89.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052569"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA052569":"AB_2681871"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.23e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.10e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"}},{"Gene":"TMEM43","Gene synonym":["ARVD5","DKFZp586G1919","LUMA","MGC3222"],"Ensembl":"ENSG00000170876","Gene description":"Transmembrane protein 43","Uniprot":["Q9BTV4"],"Chromosome":"3","Position":"14125015-14143680","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Cardiomyopathy","Disease variant","Emery-Dreifuss muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019198"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019198":"AB_1858118"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.38e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"}},{"Gene":"TMEM44","Gene synonym":["DKFZp686O18124"],"Ensembl":"ENSG00000145014","Gene description":"Transmembrane protein 44","Uniprot":["Q2T9K0"],"Chromosome":"3","Position":"194587673-194633689","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"28.3","Endothelial cells":"26.0","granulocytes":"55.9","Intestinal goblet cells":"27.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"basophil":"3.7","NK-cell":"8.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"3.7","NK-cells":"8.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043718"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043718":"AB_10794662"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.55e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"}},{"Gene":"TMEM45A","Gene synonym":["DERP7","FLJ10134"],"Ensembl":"ENSG00000181458","Gene description":"Transmembrane protein 45A","Uniprot":["Q9NWC5"],"Chromosome":"3","Position":"100492619-100577444","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skin 1":"475.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"484.4","Club cells":"528.6","Early spermatids":"253.0","Ionocytes":"620.0","Suprabasal keratinocytes":"228.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Fibroblasts","Prostate - Fibroblasts","Skin - Keratinocyte (other)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062101"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA062101":"AB_2684682"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.42e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.18e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"}},{"Gene":"TMEM45B","Gene synonym":["BC016153","FLJ40787"],"Ensembl":"ENSG00000151715","Gene description":"Transmembrane protein 45B","Uniprot":["Q96B21"],"Chromosome":"11","Position":"129815848-129860003","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"66.5","intestine":"136.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"240.8","Ionocytes":"93.9","Paneth cells":"127.6","Proximal enterocytes":"295.6","Respiratory ciliated cells":"117.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory CD4 T-cell":"3.0","naive CD4 T-cell":"3.6","neutrophil":"11.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"granulocytes":"11.7","T-cells":"3.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"92.8"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Colon - Colon enterocytes","Lung - Alveolar cells type 2","Prostate - Urothelial cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015474","HPA015878"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015474":null,"HPA015878":"AB_2205046"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"}},{"Gene":"TMEM47","Gene synonym":["BCMP1","DKFZp564E153","DKFZP761J17121","TM4SF10","VAB-9"],"Ensembl":"ENSG00000147027","Gene description":"Transmembrane protein 47","Uniprot":["Q9BQJ4"],"Chromosome":"X","Position":"34627075-34657285","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"103.2","Astrocytes":"82.9","Leydig cells":"75.0","Melanocytes":"120.2","Muller glia cells":"132.4","Peritubular cells":"93.3","Smooth muscle cells":"78.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"19.6"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046658"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA046658":"AB_2679742"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.05e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"}},{"Gene":"TMEM50A","Gene synonym":["SMP1"],"Ensembl":"ENSG00000183726","Gene description":"Transmembrane protein 50A","Uniprot":["O95807"],"Chromosome":"1","Position":"25338317-25362361","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065192"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Actin filaments","Cytosol"],"Antibody RRID":{"HPA065192":"AB_2685429"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.64e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.34e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"}},{"Gene":"TMEM50B","Gene synonym":["C21orf4"],"Ensembl":"ENSG00000142188","Gene description":"Transmembrane protein 50B","Uniprot":["P56557"],"Chromosome":"21","Position":"33432485-33479974","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034199","HPA068995"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"CAB034199":"AB_2205160","HPA068995":"AB_2686066"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.00e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.33e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-3"}},{"Gene":"TMEM51","Gene synonym":["C1orf72","FLJ10199"],"Ensembl":"ENSG00000171729","Gene description":"Transmembrane protein 51","Uniprot":["Q9NW97"],"Chromosome":"1","Position":"15152532-15220478","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"83.2","Exocrine glandular cells":"84.1","Hofbauer cells":"48.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014547","HPA019441"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA014547":"AB_1858121","HPA019441":"AB_2670142"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.16e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-3"}},{"Gene":"TMEM52","Gene synonym":[],"Ensembl":"ENSG00000178821","Gene description":"Transmembrane protein 52","Uniprot":["Q8NDY8"],"Chromosome":"1","Position":"1917590-1919279","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"pancreas":"216.2","skeletal muscle":"298.9","tongue":"207.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Skeletal myocytes":"230.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Lung - Respiratory ciliated cells","Stomach - Chief cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079372"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA079372":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"}},{"Gene":"TMEM52B","Gene synonym":["C12orf59","FLJ31166"],"Ensembl":"ENSG00000165685","Gene description":"Transmembrane protein 52B","Uniprot":["Q4KMG9"],"Chromosome":"12","Position":"10170542-10191801","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"kidney":"175.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"19","RNA single cell type specific nTPM":{"Distal tubular cells":"827.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"renal cancer":"6.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"15.7"},"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058096"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA058096":"AB_2683603"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"}},{"Gene":"TMEM53","Gene synonym":["FLJ22353","NET4"],"Ensembl":"ENSG00000126106","Gene description":"Transmembrane protein 53","Uniprot":["Q6P2H8"],"Chromosome":"1","Position":"44635238-44674481","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"59.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Late spermatids":"1019.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"plasmacytoid DC":"99.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"99.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021134"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Focal adhesion sites"],"Antibody RRID":{"HPA021134":"AB_2205162"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.96e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.02e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"}},{"Gene":"TMEM54","Gene synonym":["CAC-1"],"Ensembl":"ENSG00000121900","Gene description":"Transmembrane protein 54","Uniprot":["Q969K7"],"Chromosome":"1","Position":"32894594-32901438","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"268.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"1525.8","Intestinal goblet cells":"312.9","Paneth cells":"680.3","Proximal enterocytes":"479.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060864","HPA061992"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA060864":null,"HPA061992":"AB_2684652"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.08e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"}},{"Gene":"TMEM59","Gene synonym":["C1orf8","HSPC001"],"Ensembl":"ENSG00000116209","Gene description":"Transmembrane protein 59","Uniprot":["Q9BXS4"],"Chromosome":"1","Position":"54026681-54053504","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA075447"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"27000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA075447":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"}},{"Gene":"TMEM59L","Gene synonym":["BSMAP","C19orf4"],"Ensembl":"ENSG00000105696","Gene description":"Transmembrane protein 59 like","Uniprot":["Q9UK28"],"Chromosome":"19","Position":"18607430-18621039","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"282.6","pituitary gland":"82.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"34.8","Bipolar cells":"83.4","Excitatory neurons":"109.1","Horizontal cells":"85.2","Inhibitory neurons":"85.9","Muller glia cells":"61.3","Oligodendrocyte precursor cells":"40.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"glioma":"44.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"27.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010661"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010661":"AB_1078338"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.80e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-5"}},{"Gene":"TMEM60","Gene synonym":["C7orf35","DC32"],"Ensembl":"ENSG00000135211","Gene description":"Transmembrane protein 60","Uniprot":["Q9H2L4"],"Chromosome":"7","Position":"77793728-77798434","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062625"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062625":"AB_2684811"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.09e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"}},{"Gene":"TMEM61","Gene synonym":[],"Ensembl":"ENSG00000143001","Gene description":"Transmembrane protein 61","Uniprot":["Q8N0U2"],"Chromosome":"1","Position":"54980628-54992288","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"kidney":"23.7","parathyroid gland":"13.6","pituitary gland":"47.6","salivary gland":"19.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"21.8","Enteroendocrine cells":"26.4","Intestinal goblet cells":"56.7","Ionocytes":"43.0","Mucus glandular cells":"20.7","Salivary duct cells":"40.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"3.4","pancreatic cancer":"3.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030614"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030614":"AB_10603216"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.07e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.78e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"}},{"Gene":"TMEM62","Gene synonym":["FLJ23375"],"Ensembl":"ENSG00000137842","Gene description":"Transmembrane protein 62","Uniprot":["Q0P6H9"],"Chromosome":"15","Position":"43123279-43185144","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044461","HPA062359"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Nuclear bodies","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center","Nuclear bodies","Cytoplasmic bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA044461":"AB_2678950","HPA062359":"AB_2684747"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.72e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"}},{"Gene":"TMEM63A","Gene synonym":["KIAA0792"],"Ensembl":"ENSG00000196187","Gene description":"Transmembrane protein 63A","Uniprot":["O94886"],"Chromosome":"1","Position":"225845536-225882380","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"365.5","salivary gland":"121.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"305.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate basal glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066504","HPA066936","HPA068918"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles","Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"HPA066504":"AB_2685680","HPA066936":"AB_2685751","HPA068918":"AB_2686057"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.79e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"}},{"Gene":"TMEM63B","Gene synonym":["C6orf110","dJ421H19.2","DKFZp434P0531"],"Ensembl":"ENSG00000137216","Gene description":"Transmembrane protein 63B","Uniprot":["Q5T3F8"],"Chromosome":"6","Position":"44126914-44155519","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"78.4","Late spermatids":"109.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029249","HPA029250","HPA029251"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Plasma membrane","Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA029249":"AB_2672965","HPA029250":"AB_2672966","HPA029251":"AB_2672967"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"}},{"Gene":"TMEM63C","Gene synonym":["C14orf171","CSC1","DKFZp434P0111","hsCSC1"],"Ensembl":"ENSG00000165548","Gene description":"Transmembrane protein 63C","Uniprot":["Q9P1W3"],"Chromosome":"14","Position":"77116568-77259495","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"28.7","pituitary gland":"41.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"9.8","Enteroendocrine cells":"17.7","Excitatory neurons":"25.5","Inhibitory neurons":"21.6","Oligodendrocyte precursor cells":"15.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"5.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Colon enteroendocrine cells","Heart muscle - Cardiomyocytes","Liver - Kupffer cells","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030657"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA030657":"AB_10601699"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-7"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-3"}},{"Gene":"TMEM64","Gene synonym":["DKFZp762C1112"],"Ensembl":"ENSG00000180694","Gene description":"Transmembrane protein 64","Uniprot":["Q6YI46"],"Chromosome":"8","Position":"90621995-90791632","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"choroid plexus":"42.5","epididymis":"144.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"50.4","Leydig cells":"49.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034221"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034221":"AB_1567653"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"}},{"Gene":"TMEM65","Gene synonym":[],"Ensembl":"ENSG00000164983","Gene description":"Transmembrane protein 65","Uniprot":["Q6PI78"],"Chromosome":"8","Position":"124306189-124372701","Protein class":["Disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"71.7","Inhibitory neurons":"136.7","Microglial cells":"68.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025020"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA025020":"AB_2205178"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.56e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-1"}},{"Gene":"TMEM67","Gene synonym":["JBTS6","MGC26979","MKS3","NPHP11"],"Ensembl":"ENSG00000164953","Gene description":"Transmembrane protein 67","Uniprot":["Q5HYA8"],"Chromosome":"8","Position":"93754844-93819234","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Bardet-Biedl syndrome","Ciliopathy","Deafness","Disease variant","Intellectual disability","Joubert syndrome","Meckel syndrome","Nephronophthisis","Obesity","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"49.0","Excitatory neurons":"58.9","Respiratory ciliated cells":"112.5","Rod photoreceptor cells":"84.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Vascular Endothelial cells","Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.62e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"}},{"Gene":"TMEM68","Gene synonym":["FLJ32370"],"Ensembl":"ENSG00000167904","Gene description":"Transmembrane protein 68","Uniprot":["Q96MH6"],"Chromosome":"8","Position":"55696424-55773407","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018216","HPA019173"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA018216":"AB_2205185","HPA019173":"AB_1858129"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"}},{"Gene":"TMEM69","Gene synonym":["C1orf154","FLJ21029"],"Ensembl":"ENSG00000159596","Gene description":"Transmembrane protein 69","Uniprot":["Q5SWH9"],"Chromosome":"1","Position":"45688181-45694436","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026993"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA026993":"AB_10601824"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.24e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.66e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"}},{"Gene":"TMEM70","Gene synonym":["FLJ20533"],"Ensembl":"ENSG00000175606","Gene description":"Transmembrane protein 70","Uniprot":["Q9BUB7"],"Chromosome":"8","Position":"73972437-73982783","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"skeletal muscle":"100.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023187","CAB034226"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB034226":"AB_2205189","HPA023187":"AB_2671101"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"}},{"Gene":"TMEM71","Gene synonym":["FLJ33069"],"Ensembl":"ENSG00000165071","Gene description":"Transmembrane protein 71","Uniprot":["Q6P5X7"],"Chromosome":"8","Position":"132685007-132760712","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"33.5","heart muscle":"37.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"19.8","Kupffer cells":"31.5","Langerhans cells":"34.5","Macrophages":"23.2","monocytes":"20.0","NK-cells":"66.7","Schwann cells":"21.6","T-cells":"34.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"9.7"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"269.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"269.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"9.7","Leukemia":"8.4"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Kidney - T-cells","Lung - NK-cells (Lung)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058401","HPA070655"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA058401":"AB_2683707","HPA070655":"AB_2686292"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"}},{"Gene":"TMEM72","Gene synonym":["bA285G1.3","C10orf127","KSP37"],"Ensembl":"ENSG00000187783","Gene description":"Transmembrane protein 72","Uniprot":["A0PK05"],"Chromosome":"10","Position":"44911316-44937010","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"choroid plexus":"51.2","kidney":"74.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"25.6","Distal enterocytes":"26.8","Distal tubular cells":"24.9","Enteroendocrine cells":"6.6","Late spermatids":"16.6","Paneth cells":"11.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"renal cancer":"8.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"3.4"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Ascending Loop of Henle cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039894","HPA062907"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039894":"AB_10795261","HPA062907":"AB_2684900"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMEM74","Gene synonym":["FLJ30668","NET36"],"Ensembl":"ENSG00000164841","Gene description":"Transmembrane protein 74","Uniprot":["Q96NL1"],"Chromosome":"8","Position":"108606850-108787594","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"8.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"10.1","Cone photoreceptor cells":"8.6","Rod photoreceptor cells":"10.0","Schwann cells":"17.6","Spermatogonia":"7.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015672","HPA076461"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA015672":"AB_1858132","HPA076461":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"}},{"Gene":"TMEM74B","Gene synonym":["C20orf46","FLJ11190"],"Ensembl":"ENSG00000125895","Gene description":"Transmembrane protein 74B","Uniprot":["Q9NUR3"],"Chromosome":"20","Position":"1180561-1185415","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"27.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"20.8","Enteroendocrine cells":"15.3","Horizontal cells":"24.4","Inhibitory neurons":"15.9","Intestinal goblet cells":"20.7","Paneth cells":"16.8","Proximal enterocytes":"19.5","Smooth muscle cells":"12.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045213"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA045213":"AB_10961999"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.07e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.55e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-3"}},{"Gene":"TMEM79","Gene synonym":["FLJ16057","FLJ32254","MATT","MGC13102"],"Ensembl":"ENSG00000163472","Gene description":"Transmembrane protein 79","Uniprot":["Q9BSE2"],"Chromosome":"1","Position":"156282935-156293185","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"132.4","skin 1":"89.9","vagina":"59.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal keratinocytes":"45.3","Squamous epithelial cells":"67.4","Suprabasal keratinocytes":"163.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055214"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA055214":"AB_2682741"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.61e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.31e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"}},{"Gene":"TMEM80","Gene synonym":["FLJ38216"],"Ensembl":"ENSG00000177042","Gene description":"Transmembrane protein 80","Uniprot":["Q96HE8"],"Chromosome":"11","Position":"695428-705028","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"98.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059592","HPA067046"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 76: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA059592":"AB_2684076","HPA067046":"AB_2685769"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.47e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-3"}},{"Gene":"TMEM81","Gene synonym":["HC3107","KVLA2788","MGC75217","UNQ2788"],"Ensembl":"ENSG00000174529","Gene description":"Transmembrane protein 81","Uniprot":["Q6P7N7"],"Chromosome":"1","Position":"205083129-205084460","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"19.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052515"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA052515":"AB_2681858"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.25e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.65e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.67e-4"}},{"Gene":"TMEM82","Gene synonym":[],"Ensembl":"ENSG00000162460","Gene description":"Transmembrane protein 82","Uniprot":["A0PJX8"],"Chromosome":"1","Position":"15742499-15747982","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"24.4","kidney":"11.5","liver":"52.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"57.4","Hepatocytes":"45.3","Paneth cells":"49.8","Proximal enterocytes":"186.3","Proximal tubular cells":"43.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"10.2","renal cancer":"5.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060282"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA060282":"AB_2684241"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.80e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"TMEM86A","Gene synonym":["FLJ90119"],"Ensembl":"ENSG00000151117","Gene description":"Transmembrane protein 86A","Uniprot":["Q8N2M4"],"Chromosome":"11","Position":"18693122-18704785","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"17.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"14.3","Hofbauer cells":"36.3","Late spermatids":"11.7","Theca cells":"11.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"3.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"8.7"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Lung - Macrophages","Pancreas - Macrophages","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057119"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA057119":"AB_2683342"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"}},{"Gene":"TMEM86B","Gene synonym":["MGC30208"],"Ensembl":"ENSG00000180089","Gene description":"Transmembrane protein 86B","Uniprot":["Q8N661"],"Chromosome":"19","Position":"55226638-55228784","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"11.0","liver":"16.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"40.4","Erythroid cells":"42.8","Hepatocytes":"28.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"10.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057689"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Midbody","Centrosome"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Centrosome"],"Subcellular additional location":["Midbody"],"Antibody RRID":{"HPA057689":"AB_2683504"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.97e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"}},{"Gene":"TMEM87A","Gene synonym":["DKFZP564G2022"],"Ensembl":"ENSG00000103978","Gene description":"Transmembrane protein 87A","Uniprot":["Q8NBN3"],"Chromosome":"15","Position":"42210447-42273584","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018104","HPA018189"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA018104":"AB_1858135","HPA018189":"AB_2205198"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"}},{"Gene":"TMEM87B","Gene synonym":["FLJ14681"],"Ensembl":"ENSG00000153214","Gene description":"Transmembrane protein 87B","Uniprot":["Q96K49"],"Chromosome":"2","Position":"112055269-112119318","Protein class":["Disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Exocrine glandular cells":"109.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035183"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA035183":"AB_10600829"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.78e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.28e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.72e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-3"}},{"Gene":"TMEM88","Gene synonym":["FLJ20025","MGC71744"],"Ensembl":"ENSG00000167874","Gene description":"Transmembrane protein 88","Uniprot":["Q6PEY1"],"Chromosome":"17","Position":"7855066-7856099","Protein class":["Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"98.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Adipocytes":"176.0","Endothelial cells":"134.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"granulocytes":"1.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Rhabdoid":"57.5"},"RNA tissue cell type enrichment":["Colon - Endothelial cells","Kidney - Endothelial cells","Prostate - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052991"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052991":"AB_2682006"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.16e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.43e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"}},{"Gene":"TMEM88B","Gene synonym":[],"Ensembl":"ENSG00000205116","Gene description":"Transmembrane protein 88B","Uniprot":["A6NKF7"],"Chromosome":"1","Position":"1426128-1427787","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"196","RNA tissue specific nTPM":{"brain":"437.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"ovarian cancer":"2.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"4.0"},"RNA tissue cell type enrichment":["Kidney - Podocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065743"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA065743":"AB_2685552"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-5"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"}},{"Gene":"TMEM89","Gene synonym":[],"Ensembl":"ENSG00000183396","Gene description":"Transmembrane protein 89","Uniprot":["A2RUT3"],"Chromosome":"3","Position":"48620759-48621769","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"testis":"24.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"21","RNA single cell type specific nTPM":{"Early spermatids":"376.5","Late spermatids":"209.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053577"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053577":"AB_2682196"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"}},{"Gene":"TMEM8B","Gene synonym":["C9orf127","FP588","LINC00950","NAG-5","NGX6","NGX6a"],"Ensembl":"ENSG00000137103","Gene description":"Transmembrane protein 8B","Uniprot":["A6NDV4"],"Chromosome":"9","Position":"35814451-35865518","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Growth regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"69.2","Granulosa cells":"45.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"plasmacytoid DC":"51.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"24","RNA blood lineage specific nTPM":{"dendritic cells":"51.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052130","HPA062701"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA052130":"AB_2681740","HPA062701":"AB_2684839"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.89e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"}},{"Gene":"TMEM9","Gene synonym":["TMEM9A"],"Ensembl":"ENSG00000116857","Gene description":"Transmembrane protein 9","Uniprot":["Q9P0T7"],"Chromosome":"1","Position":"201134772-201171574","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008483"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Microtubules","Cytokinetic bridge","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Microtubules","Cytokinetic bridge","Mitotic spindle"],"Antibody RRID":{"HPA008483":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.57e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.93e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.90e-2"}},{"Gene":"TMEM91","Gene synonym":["DSPC3","FLJ27310","IFITMD6"],"Ensembl":"ENSG00000142046","Gene description":"Transmembrane protein 91","Uniprot":["Q6ZNR0"],"Chromosome":"19","Position":"41350911-41384083","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"168.0","Extravillous trophoblasts":"104.8","Late spermatids":"480.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"193.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"granulocytes":"193.3","monocytes":"51.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053240"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053240":"AB_2682085"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.54e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.52e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"}},{"Gene":"TMEM92","Gene synonym":["FLJ33318"],"Ensembl":"ENSG00000167105","Gene description":"Transmembrane protein 92","Uniprot":["Q6UXU6"],"Chromosome":"17","Position":"50271406-50281485","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"19.0","stomach 1":"23.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Proximal enterocytes":"285.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"18.3"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063009","HPA069820"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA063009":"AB_2684921","HPA069820":"AB_2686208"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.35e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-2"}},{"Gene":"TMEM94","Gene synonym":["KIAA0195"],"Ensembl":"ENSG00000177728","Gene description":"Transmembrane protein 94","Uniprot":["Q12767"],"Chromosome":"17","Position":"75441159-75500452","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008423","HPA050660"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA008423":"AB_1852283","HPA050660":"AB_2681207"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"}},{"Gene":"TMEM95","Gene synonym":["MGC129793","UNQ9390"],"Ensembl":"ENSG00000182896","Gene description":"Transmembrane protein 95","Uniprot":["Q3KNT9"],"Chromosome":"17","Position":"7355123-7357219","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Fertilization"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"testis":"11.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"51.9","Late spermatids":"36.7","Schwann cells":"12.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"}},{"Gene":"TMEM97","Gene synonym":["MAC30"],"Ensembl":"ENSG00000109084","Gene description":"Transmembrane protein 97","Uniprot":["Q5BJF2"],"Chromosome":"17","Position":"28319200-28328685","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"113.4","pancreas":"322.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"128.5","Cholangiocytes":"127.0","Granulosa cells":"214.1","Hepatocytes":"205.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells","Stomach - Chief cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044795","HPA076689"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 25: Pancreas - Digestion","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA044795":"AB_10959306","HPA076689":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"}},{"Gene":"TMEM98","Gene synonym":["DKFZP564K1964"],"Ensembl":"ENSG00000006042","Gene description":"Transmembrane protein 98","Uniprot":["Q9Y2Y6"],"Chromosome":"17","Position":"32927910-32945106","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"253.4","Thymic epithelial cells":"201.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"plasmacytoid DC":"4.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"4.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Mesothelial cells","Heart muscle - Fibroblasts","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040473","HPA053385"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA040473":"AB_10794876","HPA053385":"AB_2682134"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.14e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.10e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.85e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"}},{"Gene":"TMEM9B","Gene synonym":["C11orf15"],"Ensembl":"ENSG00000175348","Gene description":"TMEM9 domain family member B","Uniprot":["Q9NQ34"],"Chromosome":"11","Position":"8947202-8965011","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037784"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA037784":"AB_10671886"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.26e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"}},{"Gene":"TMIE","Gene synonym":["DFNB6"],"Ensembl":"ENSG00000181585","Gene description":"Transmembrane inner ear","Uniprot":["Q8NEW7"],"Chromosome":"3","Position":"46694528-46710886","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"19.6","choroid plexus":"10.5","pituitary gland":"9.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"3.8","Horizontal cells":"3.2","Skeletal myocytes":"3.0","Spermatocytes":"3.2","Spermatogonia":"3.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"6.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"2.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"T-cells":"2.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - T-cells","Kidney - Podocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038298"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038298":"AB_10675792"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-2"}},{"Gene":"TMIGD1","Gene synonym":["TMIGD","UNQ9372"],"Ensembl":"ENSG00000182271","Gene description":"Transmembrane and immunoglobulin domain containing 1","Uniprot":["Q6UXZ0"],"Chromosome":"17","Position":"30316333-30334059","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"intestine":"140.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"36","RNA single cell type specific nTPM":{"Distal enterocytes":"151.0","Proximal enterocytes":"467.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"1.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Gastric cancer":"1.7"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021946"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA021946":"AB_1858140"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMIGD2","Gene synonym":["CD28H","IGPR-1","MGC23244"],"Ensembl":"ENSG00000167664","Gene description":"Transmembrane and immunoglobulin domain containing 2","Uniprot":["Q96BF3"],"Chromosome":"19","Position":"4292232-4302431","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lymphoid tissue":"35.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"dendritic cells":"45.6","NK-cells":"76.5","T-cells":"56.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"114.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"38","RNA blood lineage specific nTPM":{"dendritic cells":"109.4","NK-cells":"89.8","T-cells":"114.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"11.2","Neuroblastoma":"3.7"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Liver - NK-cells (Liver)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011081"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011081":"AB_1079372"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-4"}},{"Gene":"TMIGD3","Gene synonym":["AD026"],"Ensembl":"ENSG00000121933","Gene description":"Transmembrane and immunoglobulin domain containing 3","Uniprot":["P0DMS9"],"Chromosome":"1","Position":"111483348-111563962","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"testis":"55.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"255.7","Hofbauer cells":"211.9","Kupffer cells":"81.1","Late spermatids":"151.8","Macrophages":"84.3","Spermatocytes":"166.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"16.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"44","RNA blood cell specific nTPM":{"eosinophil":"62.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"44","RNA blood lineage specific nTPM":{"granulocytes":"62.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"2.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Stomach - Macrophages","Testis - Early spermatids","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.58e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"}},{"Gene":"TMPO","Gene synonym":["LAP2","LEMD4","TP"],"Ensembl":"ENSG00000120802","Gene description":"Thymopoietin","Uniprot":["P42166","P42167"],"Chromosome":"12","Position":"98515579-98550351","Protein class":["Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":["Cardiomyopathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"139.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"165.0","monocytes":"178.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Mitotic cells (Skin)","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008150","CAB009847","HPA070805"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB009847":"AB_2205450","HPA008150":"AB_1079235","HPA070805":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"}},{"Gene":"TMPPE","Gene synonym":["FLJ45032"],"Ensembl":"ENSG00000188167","Gene description":"Transmembrane protein with metallophosphoesterase domain","Uniprot":["Q6ZT21"],"Chromosome":"3","Position":"33090421-33097146","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"5.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"3.1","Kupffer cells":"2.9","Rod photoreceptor cells":"2.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"2.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027019"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA027019":"AB_1848942"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"}},{"Gene":"TMPRSS11A","Gene synonym":["ECRG1","HATL1","HESP"],"Ensembl":"ENSG00000187054","Gene description":"Transmembrane serine protease 11A","Uniprot":["Q6ZMR5"],"Chromosome":"4","Position":"67909395-67964140","Protein class":["Enzymes","Predicted membrane proteins","Transporters"],"Biological process":["Cell cycle"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"86.1","lymphoid tissue":"28.4","vagina":"41.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"15.0","Serous glandular cells":"17.9","Squamous epithelial cells":"60.5","Suprabasal keratinocytes":"30.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"cervical cancer":"14.4","head and neck cancer":"11.6","lung cancer":"4.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"1.5"},"RNA tissue cell type enrichment":["Prostate - Urothelial cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078316"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA078316":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"}},{"Gene":"TMPRSS11B","Gene synonym":["HATL5"],"Ensembl":"ENSG00000185873","Gene description":"Transmembrane serine protease 11B","Uniprot":["Q86T26"],"Chromosome":"4","Position":"68226653-68245694","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"390.7","lymphoid tissue":"82.2","vagina":"118.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal keratinocytes":"39.5","Serous glandular cells":"53.6","Suprabasal keratinocytes":"127.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"cervical cancer":"2.6","head and neck cancer":"2.6","stomach cancer":"1.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"cervical cancer":"1.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.91e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMPRSS11D","Gene synonym":["ASP","HAT"],"Ensembl":"ENSG00000153802","Gene description":"Transmembrane serine protease 11D","Uniprot":["O60235"],"Chromosome":"4","Position":"67820876-67884002","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"cervix":"51.6","esophagus":"71.8","lymphoid tissue":"34.4","salivary gland":"21.0","vagina":"76.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"59.6","Basal respiratory cells":"24.3","Serous glandular cells":"49.2","Suprabasal keratinocytes":"125.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"cervical cancer":"36.0","head and neck cancer":"30.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"cervical cancer":"1.3","Esophageal cancer":"2.2","head and neck cancer":"1.8","lymphoma":"2.4"},"RNA tissue cell type enrichment":["Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077704"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA077704":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"}},{"Gene":"TMPRSS11E","Gene synonym":["DESC1","TMPRSS11E2"],"Ensembl":"ENSG00000087128","Gene description":"Transmembrane serine protease 11E","Uniprot":["Q9UL52"],"Chromosome":"4","Position":"68447463-68497604","Protein class":["Enzymes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"cervix":"89.5","esophagus":"220.2","salivary gland":"56.7","vagina":"156.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Ionocytes":"74.4","Salivary duct cells":"84.2","Suprabasal keratinocytes":"68.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"cervical cancer":"22.0","head and neck cancer":"25.3","lung cancer":"11.5","urothelial cancer":"7.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"7.9","head and neck cancer":"5.7"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043816","HPA051062"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA043816":null,"HPA051062":"AB_2681329"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.73e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"}},{"Gene":"TMPRSS11F","Gene synonym":["FLJ16046","HATL4"],"Ensembl":"ENSG00000198092","Gene description":"Transmembrane serine protease 11F","Uniprot":["Q6ZWK6"],"Chromosome":"4","Position":"68053198-68129869","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"15.2","skin 1":"9.3","vagina":"4.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"2.7","Cytotrophoblasts":"1.6","Squamous epithelial cells":"7.6","Suprabasal keratinocytes":"8.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"cervical cancer":"1.6","head and neck cancer":"2.1","lung cancer":"0.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"1.5","lymphoma":"2.2"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026911"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026911":"AB_2205589"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMPRSS12","Gene synonym":["CT151","MGC57341"],"Ensembl":"ENSG00000186452","Gene description":"Transmembrane serine protease 12","Uniprot":["Q86WS5"],"Chromosome":"12","Position":"50842920-50887884","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"50","RNA tissue specific nTPM":{"testis":"21.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Early spermatids":"62.8","Spermatocytes":"98.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"}},{"Gene":"TMPRSS13","Gene synonym":["MSPL","MSPS","TMPRSS11"],"Ensembl":"ENSG00000137747","Gene description":"Transmembrane serine protease 13","Uniprot":["Q9BYE2"],"Chromosome":"11","Position":"117900641-117929459","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"15.7","skin 1":"41.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"15.9","Extravillous trophoblasts":"22.9","Glandular and luminal cells":"11.8","Salivary duct cells":"14.2","Suprabasal keratinocytes":"21.5","Syncytiotrophoblasts":"21.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"15.9"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079555"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA079555":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"}},{"Gene":"TMPRSS15","Gene synonym":["ENTK","MGC133046","PRSS7"],"Ensembl":"ENSG00000154646","Gene description":"Transmembrane serine protease 15","Uniprot":["P98073"],"Chromosome":"21","Position":"18269116-18485879","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"512","RNA tissue specific nTPM":{"intestine":"979.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Proximal enterocytes":"27.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"liver cancer":"0.7","pancreatic cancer":"1.5","stomach cancer":"1.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"54.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"olfactory bulb":"5.0","spinal cord":"1.8"},"Antibody":["HPA015611","HPA034857","HPA072934"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA015611":"AB_1855791","HPA034857":null,"HPA072934":"AB_2732214"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TMPRSS2","Gene synonym":["PRSS10"],"Ensembl":"ENSG00000184012","Gene description":"Transmembrane serine protease 2","Uniprot":["O15393"],"Chromosome":"21","Position":"41464300-41531116","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"280.4","stomach 1":"146.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"229.6","Gastric mucus-secreting cells":"172.9","Paneth cells":"149.4","Prostatic glandular cells":"377.5","Proximal enterocytes":"170.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"prostate cancer":"250.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"prostate cancer":"271.4"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Intercalated cells","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Skin - Eccrine sweat gland cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034493","HPA035787"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA034493":null,"HPA035787":"AB_2674782"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.86e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"}},{"Gene":"TMPRSS3","Gene synonym":["DFNB10","DFNB8"],"Ensembl":"ENSG00000160183","Gene description":"Transmembrane serine protease 3","Uniprot":["P57727"],"Chromosome":"21","Position":"42371887-42396091","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"23.7","stomach 1":"14.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"17.1","Cholangiocytes":"25.0","Endometrial ciliated cells":"16.0","Gastric mucus-secreting cells":"27.4","Mucus glandular cells":"15.9","Muller glia cells":"19.1","Respiratory ciliated cells":"34.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"16.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"3.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"3.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"cervical cancer":"29.1"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 51: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.64e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"}},{"Gene":"TMPRSS4","Gene synonym":["MT-SP2","TMPRSS3"],"Ensembl":"ENSG00000137648","Gene description":"Transmembrane serine protease 4","Uniprot":["Q9NRS4"],"Chromosome":"11","Position":"118077012-118121890","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"108.7","intestine":"43.5","urinary bladder":"74.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"100.8","Basal squamous epithelial cells":"62.5","Club cells":"112.7","Distal enterocytes":"125.5","Glandular and luminal cells":"65.5","Ionocytes":"137.6","Respiratory ciliated cells":"67.6","Squamous epithelial cells":"127.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"1.8"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"2.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"68.1"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Respiratory ciliated cells","Prostate - Urothelial cells","Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006238"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA006238":"AB_1080316"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-3"}},{"Gene":"TMPRSS5","Gene synonym":["MGC141886","MGC148044"],"Ensembl":"ENSG00000166682","Gene description":"Transmembrane serine protease 5","Uniprot":["Q9H3S3"],"Chromosome":"11","Position":"113687547-113706373","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"50.6","choroid plexus":"20.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"25.6","Mucus glandular cells":"15.4","Oligodendrocytes":"14.6","Schwann cells":"17.5","Serous glandular cells":"11.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"5.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"5.3"},"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010992"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA010992":"AB_1858152"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"}},{"Gene":"TMPRSS6","Gene synonym":["FLJ30744","MT2"],"Ensembl":"ENSG00000187045","Gene description":"Transmembrane serine protease 6","Uniprot":["Q8IU80"],"Chromosome":"22","Position":"37065436-37109713","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"liver":"128.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"73.0","Late spermatids":"161.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"liver cancer":"51.3","thyroid cancer":"14.1"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"basal ganglia":"4.4","thalamus":"1.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"3.5","lymphoma":"4.0"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"3.3"},"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.16e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-5"}},{"Gene":"TMPRSS7","Gene synonym":[],"Ensembl":"ENSG00000176040","Gene description":"Transmembrane serine protease 7","Uniprot":["Q7RTY8"],"Chromosome":"3","Position":"112034843-112081269","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"1.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"7.6","Excitatory neurons":"4.0","Intestinal goblet cells":"2.1","Proximal enterocytes":"2.2","Respiratory ciliated cells":"5.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040630"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040630":"AB_10796124"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"}},{"Gene":"TMPRSS9","Gene synonym":[],"Ensembl":"ENSG00000178297","Gene description":"Transmembrane serine protease 9","Uniprot":["Q7Z410"],"Chromosome":"19","Position":"2360238-2426239","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"4.1","lymphoid tissue":"2.4","testis":"3.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"22.1","Erythroid cells":"20.5","Granulosa cells":"21.3","Late spermatids":"58.3","Sertoli cells":"11.1","Theca cells":"28.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"1.5","melanoma":"1.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051483"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051483":"AB_2681501"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"}},{"Gene":"TMTC1","Gene synonym":["ARG99","FLJ31400","FLJ41625","OLF"],"Ensembl":"ENSG00000133687","Gene description":"Transmembrane O-mannosyltransferase targeting cadherins 1","Uniprot":["Q8IUR5"],"Chromosome":"12","Position":"29500840-29784759","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"103.4","Astrocytes":"62.6","Endothelial cells":"87.0","Excitatory neurons":"183.7","Inhibitory neurons":"195.6","Skeletal myocytes":"60.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016720"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA016720":"AB_1858155"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-3"}},{"Gene":"TMTC2","Gene synonym":["DKFZp762A217"],"Ensembl":"ENSG00000179104","Gene description":"Transmembrane O-mannosyltransferase targeting cadherins 2","Uniprot":["Q8N394"],"Chromosome":"12","Position":"82686880-83134870","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"60.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Oligodendrocytes":"2031.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"28.0"},"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026954","HPA026955"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA026954":"AB_2256025","HPA026955":"AB_10602282"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.84e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"}},{"Gene":"TMTC3","Gene synonym":["FLJ90492","SMILE"],"Ensembl":"ENSG00000139324","Gene description":"Transmembrane O-mannosyltransferase targeting cadherins 3","Uniprot":["Q6ZXV5"],"Chromosome":"12","Position":"88142296-88199887","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038550"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA038550":"AB_10672715"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"}},{"Gene":"TMTC4","Gene synonym":["FLJ14624","FLJ22153"],"Ensembl":"ENSG00000125247","Gene description":"Transmembrane O-mannosyltransferase targeting cadherins 4","Uniprot":["Q5T4D3"],"Chromosome":"13","Position":"100603625-100675093","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"131.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016489","HPA057056"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA016489":"AB_1858157","HPA057056":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"}},{"Gene":"TMUB1","Gene synonym":["C7orf21","HOPS","SB144"],"Ensembl":"ENSG00000164897","Gene description":"Transmembrane and ubiquitin like domain containing 1","Uniprot":["Q9BVT8"],"Chromosome":"7","Position":"151081085-151083493","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"191.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029429"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA029429":"AB_10601825"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"}},{"Gene":"TMUB2","Gene synonym":["MGC3123"],"Ensembl":"ENSG00000168591","Gene description":"Transmembrane and ubiquitin like domain containing 2","Uniprot":["Q71RG4"],"Chromosome":"17","Position":"44186970-44191929","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"102.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043137"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043137":"AB_10794388"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"}},{"Gene":"TMX1","Gene synonym":["PDIA11","TMX","TXNDC","TXNDC1"],"Ensembl":"ENSG00000139921","Gene description":"Thioredoxin related transmembrane protein 1","Uniprot":["Q9H3N1"],"Chromosome":"14","Position":"51240162-51257655","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003085"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"26000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA003085":"AB_1080424"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-3"}},{"Gene":"TMX2","Gene synonym":["PDIA12","TXNDC14"],"Ensembl":"ENSG00000213593","Gene description":"Thioredoxin related transmembrane protein 2","Uniprot":["Q9Y320"],"Chromosome":"11","Position":"57712593-57740973","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability","Lissencephaly","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040282","HPA063763"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA040282":"AB_10697715","HPA063763":"AB_2685116"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.64e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.37e-4"}},{"Gene":"TMX3","Gene synonym":["FLJ20793","KIAA1830","PDIA13","TXNDC10"],"Ensembl":"ENSG00000166479","Gene description":"Thioredoxin related transmembrane protein 3","Uniprot":["Q96JJ7"],"Chromosome":"18","Position":"68673688-68715108","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014157"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"36000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014157":"AB_1858469"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"}},{"Gene":"TMX4","Gene synonym":["DJ971N18.2","KIAA1162","PDIA14","TXNDC13"],"Ensembl":"ENSG00000125827","Gene description":"Thioredoxin related transmembrane protein 4","Uniprot":["Q9H1E5"],"Chromosome":"20","Position":"7977346-8019805","Protein class":["Predicted membrane proteins"],"Biological process":["Electron transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"361.0","Early spermatids":"569.9","Late spermatids":"1588.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000399","HPA015752"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA000399":"AB_1858471","HPA015752":"AB_1858470"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.60e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"}},{"Gene":"TNF","Gene synonym":["DIF","TNF-alpha","TNFA","TNFSF2"],"Ensembl":"ENSG00000232810","Gene description":"Tumor necrosis factor","Uniprot":["P01375"],"Chromosome":"6","Position":"31575565-31578336","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"12.7","lymphoid tissue":"6.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"101.6","Hofbauer cells":"85.6","Langerhans cells":"60.0","Macrophages":"116.1","monocytes":"54.0","T-cells":"94.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"68.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"20.8","monocytes":"68.0","T-cells":"36.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"9.5","lymphoma":"30.9"},"RNA tissue cell type enrichment":["Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB078469"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":10100,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB078469":"AB_908070"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"}},{"Gene":"TNFRSF10A","Gene synonym":["Apo2","CD261","DR4","TRAILR-1","TRAILR1"],"Ensembl":"ENSG00000104689","Gene description":"TNF receptor superfamily member 10a","Uniprot":["O00220"],"Chromosome":"8","Position":"23190452-23225102","Protein class":["Cancer-related genes","CD markers","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"27.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054475"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054475":"AB_2682500"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.00e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"}},{"Gene":"TNFRSF10B","Gene synonym":["CD262","DR5","KILLER","TRAIL-R2","TRAILR2","TRICK2A","TRICKB"],"Ensembl":"ENSG00000120889","Gene description":"TNF receptor superfamily member 10b","Uniprot":["O14763"],"Chromosome":"8","Position":"23020133-23069031","Protein class":["Cancer-related genes","CD markers","Disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023625"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023625":"AB_1847860"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.76e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"}},{"Gene":"TNFRSF10C","Gene synonym":["CD263","DcR1","LIT","TRAILR3","TRID"],"Ensembl":"ENSG00000173535","Gene description":"TNF receptor superfamily member 10c","Uniprot":["O14798"],"Chromosome":"8","Position":"23102921-23117445","Protein class":["Cancer-related genes","CD markers","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"21.0","lymphoid tissue":"23.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"2.9","Ionocytes":"3.7","Kupffer cells":"2.5","Proximal enterocytes":"4.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"neutrophil":"3195.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"120","RNA blood lineage specific nTPM":{"granulocytes":"3195.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Lung - Neutrophil_2","Testis - Sertoli cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025635"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":14600000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB025635":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"}},{"Gene":"TNFRSF10D","Gene synonym":["CD264","DcR2","TRAILR4","TRUNDD"],"Ensembl":"ENSG00000173530","Gene description":"TNF receptor superfamily member 10d","Uniprot":["Q9UBN6"],"Chromosome":"8","Position":"23135588-23164027","Protein class":["Cancer-related genes","CD markers","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"104.0","Endothelial cells":"49.8","Gastric mucus-secreting cells":"71.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070971"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane","Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA070971":"AB_2686330"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"}},{"Gene":"TNFRSF11A","Gene synonym":["CD265","FEO","LOH18CR1","PDB2","RANK"],"Ensembl":"ENSG00000141655","Gene description":"TNF receptor superfamily member 11a","Uniprot":["Q9Y6Q6"],"Chromosome":"18","Position":"62325287-62391288","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Deafness","Disease variant","Osteopetrosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"30.5","salivary gland":"25.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"32.3","Enteroendocrine cells":"22.2","Intestinal goblet cells":"25.8","Paneth cells":"39.7","Proximal enterocytes":"23.8","Serous glandular cells":"31.9","Undifferentiated cells":"32.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"NK-cell":"5.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"NK-cells":"5.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Kidney - Macrophages","Skeletal muscle - Macrophages","Stomach - Mitotic cells (Stomach)","Testis - Spermatogonia","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010391","HPA047976"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB010391":"AB_2205352","HPA047976":"AB_2680227"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"}},{"Gene":"TNFRSF12A","Gene synonym":["CD266","FN14","TweakR"],"Ensembl":"ENSG00000006327","Gene description":"TNF receptor superfamily member 12A","Uniprot":["Q9NP84"],"Chromosome":"16","Position":"3018445-3022383","Protein class":["Cancer-related genes","CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Apoptosis","Cell adhesion","Differentiation"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"581.2","Basal respiratory cells":"586.6","Ductal cells":"837.6","Exocrine glandular cells":"903.8","Pancreatic endocrine cells":"714.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"eosinophil":"139.6","neutrophil":"102.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"139.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Ductal cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007853"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007853":"AB_1858463"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.50e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.78e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"}},{"Gene":"TNFRSF13B","Gene synonym":["CD267","IGAD2","TACI"],"Ensembl":"ENSG00000240505","Gene description":"TNF receptor superfamily member 13B","Uniprot":["O14836"],"Chromosome":"17","Position":"16929816-16972118","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"18.9","lymphoid tissue":"33.0","skeletal muscle":"62.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"26","RNA single cell type specific nTPM":{"B-cells":"122.9","Plasma cells":"135.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"41","RNA blood cell specific nTPM":{"memory B-cell":"130.9","naive B-cell":"51.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"59","RNA blood lineage specific nTPM":{"B-cells":"130.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"lymphoma":"59.0","Myeloma":"140.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Plasma cells","Breast - Plasma cells","Stomach - Plasma cells","Thyroid - Plasma cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030453"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030453":"AB_10601700"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"}},{"Gene":"TNFRSF13C","Gene synonym":["BAFFR","CD268"],"Ensembl":"ENSG00000159958","Gene description":"TNF receptor superfamily member 13C","Uniprot":["Q96RJ3"],"Chromosome":"22","Position":"41922032-41926806","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"intestine":"33.8","lymphoid tissue":"58.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"B-cells":"235.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"36","RNA blood cell specific nTPM":{"memory B-cell":"22.5","naive B-cell":"29.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"40","RNA blood lineage specific nTPM":{"B-cells":"29.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"9.5","lymphoma":"22.9"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Lung - B-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003246","CAB008380"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB008380":"AB_590602","HPA003246":"AB_1078264"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.44e-7"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"}},{"Gene":"TNFRSF14","Gene synonym":["ATAR","CD270","HVEA","HVEM","LIGHTR","TR2"],"Ensembl":"ENSG00000157873","Gene description":"TNF receptor superfamily member 14","Uniprot":["Q92956"],"Chromosome":"1","Position":"2555639-2565382","Protein class":["Cancer-related genes","CD markers","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"213.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"17.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006404","CAB026150","CAB030007"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026150":null,"CAB030007":"AB_2303380","HPA006404":"AB_1851348"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.39e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.01e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.79e-6"}},{"Gene":"TNFRSF17","Gene synonym":["BCM","BCMA","CD269","TNFRSF13A"],"Ensembl":"ENSG00000048462","Gene description":"TNF receptor superfamily member 17","Uniprot":["Q02223"],"Chromosome":"16","Position":"11965210-11968068","Protein class":["Cancer-related genes","CD markers","Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"29.0","lymphoid tissue":"47.9","stomach 1":"24.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Plasma cells":"468.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"62","RNA blood cell specific nTPM":{"memory B-cell":"124.9","naive B-cell":"108.5","plasmacytoid DC":"103.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"63","RNA blood lineage specific nTPM":{"B-cells":"124.9","dendritic cells":"103.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Myeloma":"633.3"},"RNA tissue cell type enrichment":["Adipose visceral - Plasma cells","Breast - Plasma cells","Liver - Plasma cells","Lung - Plasma cells","Pancreas - Plasma cells","Prostate - Plasma cells","Stomach - Plasma cells","Testis - Early spermatids","Thyroid - Plasma cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 14: B-cells - Humoral immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.58e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"}},{"Gene":"TNFRSF18","Gene synonym":["AITR","CD357","GITR"],"Ensembl":"ENSG00000186891","Gene description":"TNF receptor superfamily member 18","Uniprot":["Q9Y5U5"],"Chromosome":"1","Position":"1203508-1206592","Protein class":["CD markers","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"38.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Basal keratinocytes":"106.1","granulocytes":"44.2","Langerhans cells":"78.3","NK-cells":"78.3","Plasma cells":"48.5","Suprabasal keratinocytes":"77.4","T-cells":"74.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"NK-cell":"184.5","T-reg":"71.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"NK-cells":"184.5","T-cells":"71.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"47.4","Myeloma":"26.9"},"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Stomach - Plasma cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008025"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008025":"AB_1849696"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.72e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.12e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.40e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"}},{"Gene":"TNFRSF19","Gene synonym":["TAJ","TAJ-alpha","TRADE","TROY"],"Ensembl":"ENSG00000127863","Gene description":"TNF receptor superfamily member 19","Uniprot":["Q9NS68"],"Chromosome":"13","Position":"23570370-23676104","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"55.3","skin 1":"107.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"51.4","Microglial cells":"69.3","Prostatic glandular cells":"50.3","Respiratory ciliated cells":"40.0","Suprabasal keratinocytes":"53.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"52.9","skin cancer":"49.2"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Skeletal muscle - Fibroblasts","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010135"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA010135":"AB_1079797"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.87e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.13e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"}},{"Gene":"TNFRSF1A","Gene synonym":["CD120a","TNF-R","TNF-R-I","TNF-R55","TNFAR","TNFR1","TNFR60"],"Ensembl":"ENSG00000067182","Gene description":"TNF receptor superfamily member 1A","Uniprot":["P19438"],"Chromosome":"12","Position":"6328757-6342114","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":["Amyloidosis","Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"507.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004102","CAB010309"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":17700,"Blood concentration - Conc. blood MS [pg\/L]":"570000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010309":"AB_2206639","HPA004102":"AB_1846232"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.68e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.70e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"}},{"Gene":"TNFRSF1B","Gene synonym":["CD120b","p75","TNF-R-II","TNF-R75","TNFBR","TNFR2","TNFR80"],"Ensembl":"ENSG00000028137","Gene description":"TNF receptor superfamily member 1B","Uniprot":["P20333"],"Chromosome":"1","Position":"12166991-12209228","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"68.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"333.8","Kupffer cells":"274.3","Langerhans cells":"356.4","Macrophages":"236.5","monocytes":"530.0","NK-cells":"338.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"387.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"29.2"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Skeletal muscle - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004796"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":3230000,"Blood concentration - Conc. blood MS [pg\/L]":"8100000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004796":"AB_1078436"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.35e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.68e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"}},{"Gene":"TNFRSF21","Gene synonym":["CD358","DR6"],"Ensembl":"ENSG00000146072","Gene description":"TNF receptor superfamily member 21","Uniprot":["O75509"],"Chromosome":"6","Position":"47231532-47309905","Protein class":["CD markers","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Apoptosis","Host-virus interaction","Immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"urinary bladder":"148.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"131.3","dendritic cells":"184.9","Syncytiotrophoblasts":"156.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"35","RNA blood cell specific nTPM":{"plasmacytoid DC":"69.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"303","RNA blood lineage specific nTPM":{"dendritic cells":"69.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Urothelial cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006746","CAB009805"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2300000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009805":"AB_2206956","HPA006746":"AB_1078701"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.23e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"}},{"Gene":"TNFRSF25","Gene synonym":["APO-3","DDR3","DR3","LARD","TNFRSF12","TR3","TRAMP","WSL-1","WSL-LR"],"Ensembl":"ENSG00000215788","Gene description":"TNF receptor superfamily member 25","Uniprot":["Q93038"],"Chromosome":"1","Position":"6460786-6466175","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"44.0","pituitary gland":"29.9","skin 1":"25.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"28.7","Excitatory neurons":"37.0","T-cells":"38.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"MAIT T-cell":"5.6","memory CD4 T-cell":"4.4","memory CD8 T-cell":"2.2","naive CD4 T-cell":"4.4","T-reg":"7.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"T-cells":"7.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - T-cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"amygdala":"1.2","cerebral cortex":"1.4","hippocampal formation":"2.0"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069834"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Actin filaments","Focal adhesion sites"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane","Actin filaments","Focal adhesion sites"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA069834":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.46e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.09e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.65e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"}},{"Gene":"TNFRSF4","Gene synonym":["ACT35","CD134","OX40","TXGP1L"],"Ensembl":"ENSG00000186827","Gene description":"TNF receptor superfamily member 4","Uniprot":["P43489"],"Chromosome":"1","Position":"1211340-1214153","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"10.3","lymphoid tissue":"13.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"102.0","Endothelial cells":"47.3","granulocytes":"57.4","Langerhans cells":"150.5","NK-cells":"30.3","T-cells":"38.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"9.7","memory CD4 T-cell":"26.6","NK-cell":"14.7","T-reg":"35.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"granulocytes":"9.7","NK-cells":"14.7","T-cells":"35.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Leukemia":"3.8","lymphoma":"15.0","thyroid cancer":"11.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016128"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016128":"AB_626897"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.50e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.52e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"}},{"Gene":"TNFRSF8","Gene synonym":["CD30","D1S166E","KI-1"],"Ensembl":"ENSG00000120949","Gene description":"TNF receptor superfamily member 8","Uniprot":["P28908"],"Chromosome":"1","Position":"12063303-12144207","Protein class":["Cancer-related genes","CD markers","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"5.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"7.7","Kupffer cells":"6.8","Late spermatids":"10.2","Macrophages":"4.8","monocytes":"17.9","Thymic epithelial cells":"4.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"testis cancer":"9.3"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"2.3"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"59.4","non-classical monocyte":"96.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"96.6"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"lymphoma":"55.2"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hypothalamus":"5.5"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000016","HPA014823","HPA032081","HPA032082"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB000016":"AB_563546","HPA014823":null,"HPA032081":"AB_2674141","HPA032082":"AB_2674142"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"}},{"Gene":"TNFRSF9","Gene synonym":["4-1BB","CD137","ILA"],"Ensembl":"ENSG00000049249","Gene description":"TNF receptor superfamily member 9","Uniprot":["Q07011"],"Chromosome":"1","Position":"7915871-7943165","Protein class":["Cancer-related genes","CD markers","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"9.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"granulocytes":"47.7","Langerhans cells":"37.3","NK-cells":"13.7","T-cells":"25.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory CD8 T-cell":"9.4","neutrophil":"7.8","NK-cell":"5.2","T-reg":"18.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"7.8","NK-cells":"5.2","T-cells":"18.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071425"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA071425":"AB_2686394"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.69e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"}},{"Gene":"TNFSF10","Gene synonym":["Apo-2L","CD253","TL2","TRAIL"],"Ensembl":"ENSG00000121858","Gene description":"TNF superfamily member 10","Uniprot":["P50591"],"Chromosome":"3","Position":"172505508-172523475","Protein class":["Cancer-related genes","CD markers","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"391.1","Ductal cells":"673.1","Proximal tubular cells":"573.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"265.4","classical monocyte":"133.4","intermediate monocyte":"203.5","neutrophil":"257.1","non-classical monocyte":"213.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"265.4","monocytes":"213.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"head and neck cancer":"165.2","Kidney cancer":"187.4"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054938"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":67400,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054938":"AB_2682643"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.43e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"}},{"Gene":"TNFSF11","Gene synonym":["CD254","ODF","OPGL","RANKL","TRANCE"],"Ensembl":"ENSG00000120659","Gene description":"TNF superfamily member 11","Uniprot":["O14788"],"Chromosome":"13","Position":"42562736-42608013","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Differentiation"],"Molecular function":["Cytokine","Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Osteopetrosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"4.5","liver":"5.2","lymphoid tissue":"15.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"10.2","Ductal cells":"5.3","Early spermatids":"7.5","Late spermatids":"14.4","NK-cells":"4.0","Pancreatic endocrine cells":"3.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"2.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"NK-cell":"13.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"NK-cells":"13.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"2.0","thyroid cancer":"1.9"},"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009193","HPA045142"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":17200,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009193":null,"HPA045142":"AB_2679231"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"}},{"Gene":"TNFSF13","Gene synonym":["APRIL","CD256"],"Ensembl":"ENSG00000161955","Gene description":"TNF superfamily member 13","Uniprot":["O75888"],"Chromosome":"17","Position":"7558292-7561608","Protein class":["Cancer-related genes","CD markers","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Immunity"],"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"141.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"4.7","Erythroid cells":"4.6","Gastric mucus-secreting cells":"10.7","Macrophages":"10.2","Schwann cells":"8.4","Thymic epithelial cells":"13.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"438.1","intermediate monocyte":"420.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"dendritic cells":"283.5","granulocytes":"158.9","monocytes":"438.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Colon - Macrophages","Lung - Macrophages","Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004863"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":6770000,"Blood concentration - Conc. blood MS [pg\/L]":"35000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004863":"AB_1078187"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.73e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.30e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"}},{"Gene":"TNFSF13B","Gene synonym":["BAFF","BLYS","CD257","TALL-1","TALL1","THANK","TNFSF20"],"Ensembl":"ENSG00000102524","Gene description":"TNF superfamily member 13b","Uniprot":["Q9Y275"],"Chromosome":"13","Position":"108251240-108308484","Protein class":["Cancer-related genes","CD markers","FDA approved drug targets","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity"],"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"25.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"170.2","Kupffer cells":"114.2","Langerhans cells":"304.0","Macrophages":"156.7","monocytes":"428.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"505.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"206.4","granulocytes":"505.4","monocytes":"350.9"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Leukemia":"22.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009188","HPA030526"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane","Focal adhesion sites"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":393000,"Blood concentration - Conc. blood MS [pg\/L]":"790000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Focal adhesion sites"],"Antibody RRID":{"CAB009188":null,"HPA030526":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"TNFSF14","Gene synonym":["CD258","HVEM-L","LIGHT","LTg"],"Ensembl":"ENSG00000125735","Gene description":"TNF superfamily member 14","Uniprot":["O43557"],"Chromosome":"19","Position":"6661253-6670588","Protein class":["CD markers","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"adipose tissue":"29.0","liver":"107.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"45.1","T-cells":"52.8","Thymic epithelial cells":"45.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"199.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"199.7","T-cells":"61.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"4.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012700"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":41000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA012700":"AB_1852870"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.07e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"}},{"Gene":"TNFSF15","Gene synonym":["MGC129934","MGC129935","TL1","TL1A","VEGI","VEGI192A"],"Ensembl":"ENSG00000181634","Gene description":"TNF superfamily member 15","Uniprot":["O95150"],"Chromosome":"9","Position":"114784652-114806039","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"9.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"19.1","Basal respiratory cells":"25.8","Basal squamous epithelial cells":"15.9","Club cells":"20.0","Endometrial ciliated cells":"18.4","Glandular and luminal cells":"33.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012948","HPA046522"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1110000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA012948":"AB_1858024","HPA046522":"AB_2679683"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-3"}},{"Gene":"TNFSF18","Gene synonym":["AITRL","hGITRL","TL6"],"Ensembl":"ENSG00000120337","Gene description":"TNF superfamily member 18","Uniprot":["Q9UNG2"],"Chromosome":"1","Position":"173039960-173050963","Protein class":["Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"1.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"9.4","Hofbauer cells":"5.3","Langerhans cells":"2.6","Squamous epithelial cells":"5.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"10.0","ovarian cancer":"5.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.74e-2"}},{"Gene":"TNFSF4","Gene synonym":["CD252","gp34","OX-40L","TXGP1"],"Ensembl":"ENSG00000117586","Gene description":"TNF superfamily member 4","Uniprot":["P23510"],"Chromosome":"1","Position":"173183731-173207331","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Granulosa cells":"36.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"11.2"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059579"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059579":"AB_2684071"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"}},{"Gene":"TNFSF8","Gene synonym":["CD153","CD30LG"],"Ensembl":"ENSG00000106952","Gene description":"TNF superfamily member 8","Uniprot":["P32971"],"Chromosome":"9","Position":"114893343-114930595","Protein class":["Cancer-related genes","CD markers","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"18.7","lymphoid tissue":"26.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"20.9","dendritic cells":"59.5","Hofbauer cells":"19.5","Kupffer cells":"18.5","Langerhans cells":"25.0","Macrophages":"27.3","Schwann cells":"30.8","T-cells":"67.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"lymphoma":"9.6","testis cancer":"23.3"},"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Breast - Macrophages","Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"}},{"Gene":"TNFSF9","Gene synonym":["4-1BB-L","4-1BBL"],"Ensembl":"ENSG00000125657","Gene description":"TNF superfamily member 9","Uniprot":["P41273"],"Chromosome":"19","Position":"6531026-6535924","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"9.8","esophagus":"9.8","vagina":"9.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"44.2","B-cells":"52.5","dendritic cells":"79.8","Schwann cells":"52.4","Suprabasal keratinocytes":"31.8","T-cells":"41.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059857"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA059857":"AB_2684144"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-3"}},{"Gene":"TNK2","Gene synonym":["ACK","ACK1","p21cdc42Hs"],"Ensembl":"ENSG00000061938","Gene description":"Tyrosine kinase non receptor 2","Uniprot":["Q07912"],"Chromosome":"3","Position":"195863364-195911945","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Endocytosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"102.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"66.7","Oligodendrocyte precursor cells":"234.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041954","HPA069561"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA041954":"AB_10794164","HPA069561":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.96e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.30e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.00e-4"}},{"Gene":"TNMD","Gene synonym":["BRICD4","ChM1L","myodulin","TEM","tendin"],"Ensembl":"ENSG00000000005","Gene description":"Tenomodulin","Uniprot":["Q9H2S6"],"Chromosome":"X","Position":"100584936-100599885","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"21.1","breast":"12.9","seminal vesicle":"26.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Adipocytes":"73.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"testis cancer":"1.2","Uterine cancer":"1.3"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034961","HPA055634"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA034961":"AB_10670285","HPA055634":"AB_2682868"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-3"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"}},{"Gene":"TNPO2","Gene synonym":["FLJ12155","IPO3","KPNB2B","TRN2"],"Ensembl":"ENSG00000105576","Gene description":"Transportin 2","Uniprot":["O14787"],"Chromosome":"19","Position":"12699194-12724011","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Horizontal cells":"67.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB046446","HPA071498"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"CAB046446":"AB_10603392","HPA071498":"AB_2686405"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.16e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"}},{"Gene":"TNR","Gene synonym":[],"Ensembl":"ENSG00000116147","Gene description":"Tenascin R","Uniprot":["Q92752"],"Chromosome":"1","Position":"175315194-175743616","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"31.3","retina":"16.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"2191.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"46","RNA cancer specific FPKM":{"glioma":"9.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"2.2","thyroid cancer":"3.6"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Beta cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022343","HPA027134","HPA027150","HPA029859"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022343":null,"HPA027134":"AB_1851983","HPA027150":"AB_1851985","HPA029859":"AB_10600916"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"}},{"Gene":"TOGARAM1","Gene synonym":["crescerin","Crescerin-1","FAM179B","KIAA0423"],"Ensembl":"ENSG00000198718","Gene description":"TOG array regulator of axonemal microtubules 1","Uniprot":["Q9Y4F4"],"Chromosome":"14","Position":"44962190-45074431","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Joubert syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"101.7","Oligodendrocytes":"145.4","Rod photoreceptor cells":"121.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"4.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"4.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053559"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053559":"AB_2682190"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"}},{"Gene":"TOMM20","Gene synonym":["KIAA0016","MAS20","MOM19","TOM20"],"Ensembl":"ENSG00000173726","Gene description":"Translocase of outer mitochondrial membrane 20","Uniprot":["Q15388"],"Chromosome":"1","Position":"235109341-235128837","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005585","HPA011562"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB005585":"AB_628381","HPA011562":"AB_1080326"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"}},{"Gene":"TOMM20L","Gene synonym":["UNQ9438"],"Ensembl":"ENSG00000196860","Gene description":"Translocase of outer mitochondrial membrane 20 like","Uniprot":["Q6UXN7"],"Chromosome":"14","Position":"58395928-58408702","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"testis":"10.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"191.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076397"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA076397":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-3"}},{"Gene":"TOMM22","Gene synonym":["TOM22"],"Ensembl":"ENSG00000100216","Gene description":"Translocase of outer mitochondrial membrane 22","Uniprot":["Q9NS69"],"Chromosome":"22","Position":"38681957-38685421","Protein class":["Predicted membrane proteins"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003037","HPA074642"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"230000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA003037":"AB_1080329","HPA074642":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.90e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"}},{"Gene":"TOMM5","Gene synonym":["bA613M10.3","C9orf105","Tom5"],"Ensembl":"ENSG00000175768","Gene description":"Translocase of outer mitochondrial membrane 5","Uniprot":["Q8N4H5"],"Chromosome":"9","Position":"37582646-37592604","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"257.5","Squamous epithelial cells":"236.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048712"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA048712":"AB_2680499"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.09e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.49e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.37e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"}},{"Gene":"TOMM6","Gene synonym":["OBTP","Tom6"],"Ensembl":"ENSG00000214736","Gene description":"Translocase of outer mitochondrial membrane 6","Uniprot":["Q96B49"],"Chromosome":"6","Position":"41787662-41789898","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"179","RNA single cell type specific nTPM":{"Astrocytes":"30.0","Excitatory neurons":"16.2","Inhibitory neurons":"15.1","Microglial cells":"10.0","Oligodendrocyte precursor cells":"11.6","Oligodendrocytes":"24.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004801"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA004801":"AB_1859553"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TOMM7","Gene synonym":["Tom7"],"Ensembl":"ENSG00000196683","Gene description":"Translocase of outer mitochondrial membrane 7","Uniprot":["Q9P0U1"],"Chromosome":"7","Position":"22812628-22822852","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.30e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"}},{"Gene":"TOMM70","Gene synonym":["KIAA0719","Tom70","TOMM70A"],"Ensembl":"ENSG00000154174","Gene description":"Translocase of outer mitochondrial membrane 70","Uniprot":["O94826"],"Chromosome":"3","Position":"100363431-100401089","Protein class":["Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014589","CAB017156","HPA048020"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB017156":null,"HPA014589":"AB_1858185","HPA048020":"AB_2680234"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-3"}},{"Gene":"TOP1MT","Gene synonym":[],"Ensembl":"ENSG00000184428","Gene description":"DNA topoisomerase I mitochondrial","Uniprot":["Q969P6"],"Chromosome":"8","Position":"143304384-143359979","Protein class":["Enzymes","FDA approved drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["DNA-binding","Isomerase","Topoisomerase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001915","HPA021542"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA001915":"AB_1080331","HPA021542":"AB_1858186"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"}},{"Gene":"TOR1A","Gene synonym":["DQ2","DYT1"],"Ensembl":"ENSG00000136827","Gene description":"Torsin family 1 member A","Uniprot":["O14656"],"Chromosome":"9","Position":"129812942-129824244","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone","Hydrolase"],"Disease involvement":["Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012473","HPA051195"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nuclear membrane","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB012473":"AB_2240792","HPA051195":"AB_2681382"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.45e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"}},{"Gene":"TOR1AIP1","Gene synonym":["FLJ13142","LAP1","LAP1B","LAP1C"],"Ensembl":"ENSG00000143337","Gene description":"Torsin 1A interacting protein 1","Uniprot":["Q5JTV8"],"Chromosome":"1","Position":"179882042-179920077","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Limb-girdle muscular dystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"236.0","Late spermatids":"235.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047151","HPA050546","HPA070991"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA047151":"AB_2679956","HPA050546":"AB_2681167","HPA070991":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"}},{"Gene":"TOR1AIP2","Gene synonym":["IFRG15","LULL1","NET9"],"Ensembl":"ENSG00000169905","Gene description":"Torsin 1A interacting protein 2","Uniprot":["Q8NFQ8","Q9H496"],"Chromosome":"1","Position":"179839967-179877803","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051849","HPA058348","HPA070542"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA051849":"AB_2681637","HPA058348":"AB_2683687","HPA070542":"AB_2686278"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"TOR1B","Gene synonym":["DQ1","MGC4386"],"Ensembl":"ENSG00000136816","Gene description":"Torsin family 1 member B","Uniprot":["O14657"],"Chromosome":"9","Position":"129803157-129811281","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013403","HPA013697","CAB022709"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB022709":null,"HPA013403":"AB_1858195","HPA013697":"AB_1858196"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"}},{"Gene":"TOR4A","Gene synonym":["C9orf167","FLJ20245"],"Ensembl":"ENSG00000198113","Gene description":"Torsin family 4 member A","Uniprot":["Q9NXH8"],"Chromosome":"9","Position":"137277726-137282641","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"33.2","Undifferentiated cells":"26.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044913"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA044913":"AB_10965030"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.48e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.44e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"}},{"Gene":"TOX2","Gene synonym":["C20orf100","dJ1108D11.2","GCX-1"],"Ensembl":"ENSG00000124191","Gene description":"TOX high mobility group box family member 2","Uniprot":["Q96NM4"],"Chromosome":"20","Position":"43914852-44069616","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"50.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"48.8","Inhibitory neurons":"75.1","Late spermatids":"22.8","Oligodendrocyte precursor cells":"43.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"6.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"49.5"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Kidney - Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049900","HPA058396"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA049900":"AB_2680942","HPA058396":"AB_2683704"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.60e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.45e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"}},{"Gene":"TP53AIP1","Gene synonym":["p53AIP1"],"Ensembl":"ENSG00000120471","Gene description":"Tumor protein p53 regulated apoptosis inducing protein 1","Uniprot":["Q9HCN2"],"Chromosome":"11","Position":"128934731-128943399","Protein class":["Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"24.5","lymphoid tissue":"29.5","skin 1":"20.4","vagina":"13.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"48.1","Basal respiratory cells":"40.9","Basal squamous epithelial cells":"144.5","Breast myoepithelial cells":"28.3","Endometrial ciliated cells":"38.1","Squamous epithelial cells":"55.0","Suprabasal keratinocytes":"33.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"4.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"2.7"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044300","HPA048797"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044300":"AB_2678888","HPA048797":"AB_2680524"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-7"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"}},{"Gene":"TP53BP1","Gene synonym":["53BP1","p202","TDRD30"],"Ensembl":"ENSG00000067369","Gene description":"Tumor protein p53 binding protein 1","Uniprot":["Q12888"],"Chromosome":"15","Position":"43403061-43510728","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004083","HPA008788","HPA022133","CAB079980"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Mitotic chromosome","Vesicles"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm","Mitotic chromosome","Vesicles"],"Antibody RRID":{"CAB004083":"AB_10694558","CAB079980":null,"HPA008788":"AB_1078070","HPA022133":"AB_1844382"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"}},{"Gene":"TP53I11","Gene synonym":["PIG11"],"Ensembl":"ENSG00000175274","Gene description":"Tumor protein p53 inducible protein 11","Uniprot":["O14683"],"Chromosome":"11","Position":"44885903-44951306","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Late spermatids":"484.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"41.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059727","HPA061276"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA059727":"AB_2684113","HPA061276":"AB_2684461"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.33e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.12e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.65e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"}},{"Gene":"TP53I13","Gene synonym":["DSCP1"],"Ensembl":"ENSG00000167543","Gene description":"Tumor protein p53 inducible protein 13","Uniprot":["Q8NBR0"],"Chromosome":"17","Position":"29566052-29573157","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"110.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.13e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"}},{"Gene":"TPBG","Gene synonym":["5T4","5T4-AG"],"Ensembl":"ENSG00000146242","Gene description":"Trophoblast glycoprotein","Uniprot":["Q13641"],"Chromosome":"6","Position":"82363206-82367420","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"108.3","Extravillous trophoblasts":"94.8","Thymic epithelial cells":"90.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"MAIT T-cell":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"T-cells":"1.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Lung - Fibroblast_2","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010554"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"310000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA010554":"AB_1858206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.68e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"}},{"Gene":"TPBGL","Gene synonym":[],"Ensembl":"ENSG00000261594","Gene description":"Trophoblast glycoprotein like","Uniprot":["P0DKB5"],"Chromosome":"11","Position":"75240774-75243704","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"10.7","testis":"4.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"14.7","Melanocytes":"3.5","Muller glia cells":"7.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"5.1"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"medulla oblongata":"10.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"2.6","skin cancer":"1.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"}},{"Gene":"TPCN1","Gene synonym":["FLJ20612","KIAA1169","TPC1"],"Ensembl":"ENSG00000186815","Gene description":"Two pore segment channel 1","Uniprot":["Q9ULQ1"],"Chromosome":"12","Position":"113221050-113298585","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"168.9","Microglial cells":"77.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039757"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039757":"AB_10795156"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-3"}},{"Gene":"TPCN2","Gene synonym":["TPC2"],"Ensembl":"ENSG00000162341","Gene description":"Two pore segment channel 2","Uniprot":["Q8NHX9"],"Chromosome":"11","Position":"69048932-69136316","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"30.1","Inhibitory neurons":"22.0","Melanocytes":"41.8","Oligodendrocyte precursor cells":"25.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016561","HPA027080"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA016561":"AB_1858207","HPA027080":"AB_10600917"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.96e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"}},{"Gene":"TPGS1","Gene synonym":["C19orf20","GTRGEO22","PGs1"],"Ensembl":"ENSG00000141933","Gene description":"Tubulin polyglutamylase complex subunit 1","Uniprot":["Q6ZTW0"],"Chromosome":"19","Position":"507497-519654","Protein class":["Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"145.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"5.3","granulocytes":"3.9","T-cells":"3.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.24e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.82e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-3"}},{"Gene":"TPM1","Gene synonym":["C15orf13","CMH3"],"Ensembl":"ENSG00000140416","Gene description":"Tropomyosin 1","Uniprot":["P09493"],"Chromosome":"15","Position":"63042632-63071915","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Actin-binding","Muscle protein"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"10621.0","skeletal muscle":"12678.0","tongue":"5183.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"15062.8","Exocrine glandular cells":"2704.5","Extravillous trophoblasts":"3641.6","Pancreatic endocrine cells":"3058.9","Skeletal myocytes":"5271.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"48.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"14.1","granulocytes":"48.7","monocytes":"19.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"3810.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Smooth muscle cells","Heart muscle - Cardiomyocytes","Kidney - Fibroblasts","Lung - Smooth muscle cells","Prostate - Smooth muscle cells","Skeletal muscle - Skeletal myocytes","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000261","HPA009066","CAB017698","HPA047089","HPA053624"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB017698":"AB_2272017","HPA000261":"AB_1080339","HPA009066":"AB_1080342","HPA047089":"AB_2679928","HPA053624":"AB_2682210"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.30e-4"}},{"Gene":"TPO","Gene synonym":["TPX"],"Ensembl":"ENSG00000115705","Gene description":"Thyroid peroxidase","Uniprot":["P07202"],"Chromosome":"2","Position":"1374066-1543711","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Hydrogen peroxide","Thyroid hormones biosynthesis"],"Molecular function":["Oxidoreductase","Peroxidase"],"Disease involvement":["Congenital hypothyroidism","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"70","RNA tissue specific nTPM":{"thyroid gland":"1588.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"25.2","Cardiomyocytes":"4.3","Early spermatids":"4.6","Endothelial cells":"15.2","Late spermatids":"7.4","Skeletal myocytes":"4.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"364","RNA cancer specific FPKM":{"thyroid cancer":"188.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"memory CD4 T-cell":"2.0","T-reg":"1.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"T-cells":"2.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"4.4","thyroid cancer":"5.9"},"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007987","CAB009587","HPA073226"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009587":null,"HPA007987":"AB_1080270","HPA073226":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-3"}},{"Gene":"TPRA1","Gene synonym":["FLJ32197","GPR175","TMEM227","TPRA40"],"Ensembl":"ENSG00000163870","Gene description":"Transmembrane protein adipocyte associated 1","Uniprot":["Q86W33"],"Chromosome":"3","Position":"127571232-127598267","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"223.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019784"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA019784":"AB_2670266"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.46e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"}},{"Gene":"TPRN","Gene synonym":["C9orf75","DFNB79","FLJ90254"],"Ensembl":"ENSG00000176058","Gene description":"Taperin","Uniprot":["Q4KMQ1"],"Chromosome":"9","Position":"137191617-137204193","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"56.4","pancreas":"91.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"53.6","Distal enterocytes":"134.4","Proximal enterocytes":"82.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"23.6"},"Antibody":["HPA020899","HPA076667"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA020899":"AB_1845835","HPA076667":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.13e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.16e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"}},{"Gene":"TPSG1","Gene synonym":["PRSS31","TMT"],"Ensembl":"ENSG00000116176","Gene description":"Tryptase gamma 1","Uniprot":["Q9NRR2"],"Chromosome":"16","Position":"1221651-1225257","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"14.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Intestinal goblet cells":"253.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"5.2"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"1.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Mast cells","Breast - Breast glandular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060458"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA060458":"AB_2684283"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.76e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"}},{"Gene":"TPTE","Gene synonym":["CT44","PTEN2"],"Ensembl":"ENSG00000274391","Gene description":"Transmembrane phosphatase with tensin homology","Uniprot":["P56180"],"Chromosome":"21","Position":"10521553-10606140","Protein class":["Enzymes","Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"201","RNA tissue specific nTPM":{"testis":"107.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Spermatocytes":"15.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"testis cancer":"0.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"7.6"},"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049690","HPA068342"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 36: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA049690":"AB_2680850","HPA068342":"AB_2685976"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TPTE2","Gene synonym":["TPIP"],"Ensembl":"ENSG00000132958","Gene description":"Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2","Uniprot":["Q6XPS3"],"Chromosome":"13","Position":"19422877-19536762","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"testis":"7.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"4.7","Early spermatids":"11.4","Excitatory neurons":"4.5","Inhibitory neurons":"6.1","Microglial cells":"3.6","Oligodendrocyte precursor cells":"7.2","Oligodendrocytes":"3.4","Spermatocytes":"12.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"testis cancer":"0.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"30","RNA cell line specific nTPM":{"Bone cancer":"19.5"},"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA068342"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"HPA068342":"AB_2685976"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-3"}},{"Gene":"TRABD","Gene synonym":["PP2447"],"Ensembl":"ENSG00000170638","Gene description":"TraB domain containing","Uniprot":["Q9H4I3"],"Chromosome":"22","Position":"50185913-50199598","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"187.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000822"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA000822":"AB_10959384"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.19e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.85e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"}},{"Gene":"TRABD2A","Gene synonym":["C2orf89","TIKI1"],"Ensembl":"ENSG00000186854","Gene description":"TraB domain containing 2A","Uniprot":["Q86V40"],"Chromosome":"2","Position":"84821650-84907008","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"42.7","lymphoid tissue":"11.4","ovary":"26.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"540.6","Late spermatids":"358.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"colorectal cancer":"14.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"71.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"T-cells":"71.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"33.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045817"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 24: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045817":"AB_2679460"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"}},{"Gene":"TRABD2B","Gene synonym":["TIKI2"],"Ensembl":"ENSG00000269113","Gene description":"TraB domain containing 2B","Uniprot":["A6NFA1"],"Chromosome":"1","Position":"47760528-47997385","Protein class":["Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"16.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"5.8","Fibroblasts":"6.7","Hepatocytes":"10.2","Microglial cells":"7.3","Proximal tubular cells":"20.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"renal cancer":"12.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"4.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Enteric glia cells","Thyroid - Smooth muscle cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045817"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"41000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045817":"AB_2679460"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"}},{"Gene":"TRAC","Gene synonym":[],"Ensembl":"ENSG00000277734","Gene description":"T cell receptor alpha constant","Uniprot":[],"Chromosome":"14","Position":"22547506-22552156","Protein class":["Predicted membrane proteins","T-cell receptor genes"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lymphoid tissue":"787.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"T-cells":"504.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"MAIT T-cell":"2123.1","memory CD4 T-cell":"2939.7","memory CD8 T-cell":"2508.6","naive CD4 T-cell":"2671.8","naive CD8 T-cell":"2388.0","T-reg":"4379.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"41","RNA blood lineage specific nTPM":{"T-cells":"4379.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"132.2","lymphoma":"81.4"},"RNA tissue cell type enrichment":["Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Liver - T-cells","Lung - T-cells","Pancreas - T-cells","Prostate - T-cells","Skeletal muscle - Fibroblasts","Stomach - T-cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.21e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.87e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.15e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.25e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.40e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"}},{"Gene":"TRAM1","Gene synonym":["TRAM","TRAMP"],"Ensembl":"ENSG00000067167","Gene description":"Translocation associated membrane protein 1","Uniprot":["Q15629"],"Chromosome":"8","Position":"70573218-70608416","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction","Protein transport","Translocation","Transport","Unfolded protein response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"892.9","Plasma cells":"630.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023929"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023929":"AB_1858239"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.06e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.79e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"}},{"Gene":"TRAM1L1","Gene synonym":["MGC26568"],"Ensembl":"ENSG00000174599","Gene description":"Translocation associated membrane protein 1 like 1","Uniprot":["Q8N609"],"Chromosome":"4","Position":"117083554-117085576","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"6.9","Oligodendrocyte precursor cells":"7.7","Oligodendrocytes":"12.7","Prostatic glandular cells":"6.7","Spermatogonia":"6.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044560"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA044560":"AB_10796097"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"}},{"Gene":"TRAM2","Gene synonym":["KIAA0057"],"Ensembl":"ENSG00000065308","Gene description":"Translocation associated membrane protein 2","Uniprot":["Q15035"],"Chromosome":"6","Position":"52497408-52577060","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"126.3","Plasma cells":"92.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035092","HPA057925"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035092":"AB_10610562","HPA057925":"AB_2683557"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.88e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.41e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"}},{"Gene":"TRANK1","Gene synonym":["KIAA0342","LBA1"],"Ensembl":"ENSG00000168016","Gene description":"Tetratricopeptide repeat and ankyrin repeat containing 1","Uniprot":["O15050"],"Chromosome":"3","Position":"36826819-36945057","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"45.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"55.7","Granulosa cells":"71.6","Inhibitory neurons":"89.7","Microglial cells":"51.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"115.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"115.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"22.9"},"RNA tissue cell type enrichment":["Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035508"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA035508":"AB_10671105"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"}},{"Gene":"TRAPPC12","Gene synonym":["CGI-87","TTC-15","TTC15"],"Ensembl":"ENSG00000171853","Gene description":"Trafficking protein particle complex 12","Uniprot":["Q8WVT3"],"Chromosome":"2","Position":"3379675-3485094","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["ER-Golgi transport","Transport"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"96.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"268.9","Late spermatids":"505.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034799","HPA043196"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA034799":"AB_10600920","HPA043196":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.80e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.15e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"}},{"Gene":"TRARG1","Gene synonym":["BEC-1","DSPB1","IFITMD3","LOST1","TUSC5"],"Ensembl":"ENSG00000184811","Gene description":"Trafficking regulator of GLUT4 (SLC2A4) 1","Uniprot":["Q8IXB3"],"Chromosome":"17","Position":"1279662-1300978","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"34","RNA tissue specific nTPM":{"adipose tissue":"101.4","breast":"68.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"2.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skin - Adipocytes (Skin)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050825"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA050825":"AB_2681252"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-1"}},{"Gene":"TRAT1","Gene synonym":["HSPC062","TCRIM","TRIM"],"Ensembl":"ENSG00000163519","Gene description":"T cell receptor associated transmembrane adaptor 1","Uniprot":["Q6PIZ9"],"Chromosome":"3","Position":"108822770-108855005","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"27","RNA tissue specific nTPM":{"lymphoid tissue":"79.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"T-cells":"118.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"395.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"155","RNA blood lineage specific nTPM":{"granulocytes":"395.1","T-cells":"313.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"10.2","lymphoma":"2.5","Myeloma":"2.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Kidney - T-cells","Liver - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002356","CAB026130","HPA072760"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Mitotic spindle","Centriolar satellite"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Mitotic spindle","Centriolar satellite"],"Antibody RRID":{"CAB026130":null,"HPA002356":"AB_1080375","HPA072760":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"}},{"Gene":"TRBC1","Gene synonym":["BV05S1J2.2","TCRBC1"],"Ensembl":"ENSG00000211751","Gene description":"T cell receptor beta constant 1","Uniprot":[],"Chromosome":"7","Position":"142791694-142793368","Protein class":["Predicted membrane proteins","T-cell receptor genes"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"lymphoid tissue":"1520.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"NK-cells":"443.4","T-cells":"435.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"3232.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"3232.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"98.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - T-cells","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-3"}},{"Gene":"TRBC2","Gene synonym":["TCRBC2"],"Ensembl":"ENSG00000211772","Gene description":"T cell receptor beta constant 2","Uniprot":[],"Chromosome":"7","Position":"142801041-142802748","Protein class":["Predicted membrane proteins","T-cell receptor genes"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"115.8","lymphoid tissue":"190.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"150.2","NK-cells":"264.0","T-cells":"515.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"76.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"T-cells":"76.0"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"Leukemia":"12.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Kidney - T-cells","Liver - T-cells","Lung - T-cells","Pancreas - T-cells","Prostate - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.04e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.80e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.42e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.58e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.81e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.90e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-3"}},{"Gene":"TRDC","Gene synonym":[],"Ensembl":"ENSG00000211829","Gene description":"T cell receptor delta constant","Uniprot":[],"Chromosome":"14","Position":"22462932-22465787","Protein class":["Predicted membrane proteins","T-cell receptor genes"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"lymphoid tissue":"404.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"NK-cells":"474.1","T-cells":"132.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"19.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"87","RNA blood cell specific nTPM":{"gdT-cell":"5873.4","NK-cell":"2243.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"150","RNA blood lineage specific nTPM":{"NK-cells":"2243.9","T-cells":"5873.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"18.7","Leukemia":"53.7"},"RNA tissue cell type enrichment":["Heart muscle - T-cells","Liver - NK-cells (Liver)","Lung - NK-cells (Lung)","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.25e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.13e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.67e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"}},{"Gene":"TRDN","Gene synonym":["TRISK"],"Ensembl":"ENSG00000186439","Gene description":"Triadin","Uniprot":["Q13061"],"Chromosome":"6","Position":"123216339-123637093","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"421.6","skeletal muscle":"1944.1","tongue":"1018.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Cardiomyocytes":"1553.8","Muller glia cells":"599.3","Skeletal myocytes":"2078.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"head and neck cancer":"2.2","prostate cancer":"0.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"17","RNA cell line specific nTPM":{"Rhabdoid":"15.6"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"10","RNA mouse brain regional specific nTPM":{"olfactory bulb":"11.0"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"23","RNA pig brain regional specific nTPM":{"olfactory bulb":"28.9"},"Antibody":["HPA038226","HPA058226"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"HPA038226":"AB_10795574","HPA058226":"AB_2683643"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"}},{"Gene":"TREM1","Gene synonym":["CD354","TREM-1"],"Ensembl":"ENSG00000124731","Gene description":"Triggering receptor expressed on myeloid cells 1","Uniprot":["Q9NP99"],"Chromosome":"6","Position":"41267926-41286682","Protein class":["CD markers","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Immunity","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"96.0","lung":"65.3","lymphoid tissue":"44.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"123.6","Kupffer cells":"66.0","Langerhans cells":"35.2","Macrophages":"103.3","monocytes":"204.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"lung cancer":"9.6"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"8.5"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"615.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"615.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"6.2"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Colon - Neutrophils","Stomach - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005563","HPA053612"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA005563":"AB_1858259","HPA053612":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"}},{"Gene":"TREM2","Gene synonym":["TREM-2","Trem2a","Trem2b","Trem2c"],"Ensembl":"ENSG00000095970","Gene description":"Triggering receptor expressed on myeloid cells 2","Uniprot":["Q9NZC2"],"Chromosome":"6","Position":"41158506-41163186","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"69.8","lung":"30.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Hofbauer cells":"916.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"93.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"2.0"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"dendritic cells":"2.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"2.0","Leukemia":"2.4","testis cancer":"1.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Kidney - Macrophages","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skin - Sebaceous gland cells","Testis - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010917","HPA012571"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA010917":"AB_1080365","HPA012571":"AB_1858260"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.24e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"}},{"Gene":"TREML1","Gene synonym":["dJ238O23.3","TLT1"],"Ensembl":"ENSG00000161911","Gene description":"Triggering receptor expressed on myeloid cells like 1","Uniprot":["Q86YW5"],"Chromosome":"6","Position":"41149342-41154337","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"8.7","brain":"4.5","lymphoid tissue":"7.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1.4","dendritic cells":"1.8","Hofbauer cells":"3.5","Langerhans cells":"2.3","Macrophages":"2.1","Microglial cells":"6.4","monocytes":"2.0","NK-cells":"2.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"92.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"49","RNA blood lineage specific nTPM":{"granulocytes":"92.4"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016700","HPA017860"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear speckles","Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"43000000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Nuclear speckles","Cytosol"],"Subcellular additional location":["Golgi apparatus","Plasma membrane"],"Antibody RRID":{"HPA016700":"AB_1858262","HPA017860":"AB_1858261"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"}},{"Gene":"TREML2","Gene synonym":["C6orf76","dJ238O23.1","FLJ13693","TLT2"],"Ensembl":"ENSG00000112195","Gene description":"Triggering receptor expressed on myeloid cells like 2","Uniprot":["Q5T2D2"],"Chromosome":"6","Position":"41189749-41201149","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"14.4","lymphoid tissue":"9.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"8.6","Early spermatids":"9.4","Late spermatids":"39.6","monocytes":"5.9","Syncytiotrophoblasts":"16.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"23.3","neutrophil":"33.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"B-cells":"23.3","dendritic cells":"9.3","granulocytes":"33.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"7.7","Myeloma":"14.5"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Lung - Neutrophil_2","Stomach - Neutrophils","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3400000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"}},{"Gene":"TREML4","Gene synonym":["TLT4"],"Ensembl":"ENSG00000188056","Gene description":"Triggering receptor expressed on myeloid cells like 4","Uniprot":["Q6UXN2"],"Chromosome":"6","Position":"41228339-41238882","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"1.5"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"4.5","neutrophil":"8.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"8.1"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Colon - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065044"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA065044":"AB_2685411"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"}},{"Gene":"TREX1","Gene synonym":["AGS1","DRN3"],"Ensembl":"ENSG00000213689","Gene description":"Three prime repair exonuclease 1","Uniprot":["Q9NSU2"],"Chromosome":"3","Position":"48465811-48467645","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Exonuclease","Hydrolase","Nuclease"],"Disease involvement":["Aicardi-Goutieres syndrome","Disease variant","Neurodegeneration","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"6.6","Basal squamous epithelial cells":"2.9","Gastric mucus-secreting cells":"2.4","Microglial cells":"5.5","Oligodendrocytes":"5.6","Plasma cells":"3.6","Squamous epithelial cells":"7.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035437","HPA046721"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035437":"AB_10672092","HPA046721":"AB_2732531"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TRGC1","Gene synonym":["C1","TCRGC1"],"Ensembl":"ENSG00000211689","Gene description":"T cell receptor gamma constant 1","Uniprot":[],"Chromosome":"7","Position":"38257879-38265678","Protein class":["Predicted membrane proteins","T-cell receptor genes"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"bone marrow":"31.7","prostate":"76.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"NK-cells":"195.1","Prostatic glandular cells":"166.2","T-cells":"67.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"141","RNA cancer specific FPKM":{"prostate cancer":"107.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"gdT-cell":"384.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"384.7"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"prostate cancer":"52.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Lung - NK-cells (Lung)","Prostate - Prostate glandular cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"}},{"Gene":"TRGC2","Gene synonym":["TCRGC2","TRGC2(2X)","TRGC2(3X)"],"Ensembl":"ENSG00000227191","Gene description":"T cell receptor gamma constant 2","Uniprot":[],"Chromosome":"7","Position":"38239580-38249572","Protein class":["Predicted membrane proteins","T-cell receptor genes"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"30.5","lymphoid tissue":"34.6","prostate":"23.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"NK-cells":"84.0","T-cells":"110.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"18","RNA cancer specific FPKM":{"prostate cancer":"26.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"720.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"T-cells":"720.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"23","RNA cell line specific nTPM":{"Leukemia":"42.6","prostate cancer":"13.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Liver - T-cells","Pancreas - T-cells","Prostate - Prostate glandular cells","Skin - T-cells","Testis - Early spermatids","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.06e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-3"}},{"Gene":"TRHDE","Gene synonym":["PAP-II","PGPEP2","TRH-DE"],"Ensembl":"ENSG00000072657","Gene description":"Thyrotropin releasing hormone degrading enzyme","Uniprot":["Q9UKU6"],"Chromosome":"12","Position":"72087266-72670758","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Aminopeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"7.6","pancreas":"10.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"213.3","Inhibitory neurons":"285.3","Late spermatids":"67.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"1.9"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"basal ganglia":"4.9","cerebellum":"4.4","cerebral cortex":"2.5","hippocampal formation":"7.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"6.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Lung - Fibroblast_1","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7300000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.53e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"}},{"Gene":"TRHR","Gene synonym":[],"Ensembl":"ENSG00000174417","Gene description":"Thyrotropin releasing hormone receptor","Uniprot":["P34981"],"Chromosome":"8","Position":"109086585-109121565","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Congenital hypothyroidism","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"5.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055162"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055162":"AB_2732592"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TRIB1","Gene synonym":["C8FW","GIG2","TRB1"],"Ensembl":"ENSG00000173334","Gene description":"Tribbles pseudokinase 1","Uniprot":["Q96RU8"],"Chromosome":"8","Position":"125430358-125438403","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Protein kinase inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"365.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"248.2","Endometrial stromal cells":"232.2","Plasma cells":"265.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"9.9","neutrophil":"4.7","non-classical monocyte":"3.5","T-reg":"2.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"granulocytes":"9.9","monocytes":"3.5","T-cells":"2.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"127.2"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063982"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 26: NCI-H716 - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA063982":"AB_2685165"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"}},{"Gene":"TRIB2","Gene synonym":["GS3955","TRB2"],"Ensembl":"ENSG00000071575","Gene description":"Tribbles pseudokinase 2","Uniprot":["Q92519"],"Chromosome":"2","Position":"12716889-12742734","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Protein kinase inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"75.1","Leydig cells":"80.8","Muller glia cells":"95.2","Peritubular cells":"75.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"74.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"48.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"B-cells":"12.2","NK-cells":"19.3","T-cells":"48.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"115.8","skin cancer":"121.4"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Liver - Vascular Endothelial cells","Skin - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001305"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA001305":"AB_1080371"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"}},{"Gene":"TRIB3","Gene synonym":["C20orf97","dJ1103G7.3","TRB3"],"Ensembl":"ENSG00000101255","Gene description":"Tribbles pseudokinase 3","Uniprot":["Q96RU7"],"Chromosome":"20","Position":"362835-397559","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Stress response","Transcription","Transcription regulation"],"Molecular function":["Protein kinase inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"80.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"47.3","Exocrine glandular cells":"32.4","Hepatocytes":"31.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015272","HPA055442"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015272":"AB_1858269","HPA055442":"AB_2682818"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.75e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.07e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"}},{"Gene":"TRIL","Gene synonym":["KIAA0644"],"Ensembl":"ENSG00000255690","Gene description":"TLR4 interactor with leucine rich repeats","Uniprot":["Q7L0X0"],"Chromosome":"7","Position":"28953358-28958330","Protein class":["Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"68.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"69.9","Fibroblasts":"15.2","Muller glia cells":"17.7","Oligodendrocyte precursor cells":"12.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"20.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"7.8","Neuroblastoma":"5.1"},"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts","Kidney - Fibroblasts","Stomach - Fibroblasts","Testis - Early spermatids","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.23e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.52e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"}},{"Gene":"TRIM13","Gene synonym":["DLEU5","Leu5","RFP2","RNF77"],"Ensembl":"ENSG00000204977","Gene description":"Tripartite motif containing 13","Uniprot":["O60858"],"Chromosome":"13","Position":"49995888-50020481","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"680.9","Spermatocytes":"177.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000367"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000367":"AB_1856196"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"}},{"Gene":"TRIM55","Gene synonym":["MURF-2","RNF29"],"Ensembl":"ENSG00000147573","Gene description":"Tripartite motif containing 55","Uniprot":["Q9BYV6"],"Chromosome":"8","Position":"66126896-66175485","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Muscle protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"heart muscle":"61.8","liver":"37.9","skeletal muscle":"29.6","tongue":"33.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"161.8","Endometrial ciliated cells":"61.6","Hepatocytes":"35.0","Skeletal myocytes":"144.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"liver cancer":"12.3","renal cancer":"5.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"1.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Kidney cancer":"37.2","Rhabdoid":"56.1","testis cancer":"91.0"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038793","HPA053691"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA038793":"AB_10673289","HPA053691":"AB_2682231"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"}},{"Gene":"TRIM59","Gene synonym":["Mrf1","RNF104","TRIM57","TSBF1"],"Ensembl":"ENSG00000213186","Gene description":"Tripartite motif containing 59","Uniprot":["Q8IWR1"],"Chromosome":"3","Position":"160432445-160485773","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"68.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Oligodendrocytes":"369.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Mitotic cells (Skin)","Stomach - Mitotic cells (Stomach)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017750"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Rods & Rings"],"Subcellular additional location":null,"Antibody RRID":{"HPA017750":"AB_1858312"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.36e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.15e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-3"}},{"Gene":"TRIO","Gene synonym":["ARHGEF23"],"Ensembl":"ENSG00000038382","Gene description":"Trio Rho guanine nucleotide exchange factor","Uniprot":["O75962"],"Chromosome":"5","Position":"14143342-14532128","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"199.3","Excitatory neurons":"395.1","Inhibitory neurons":"433.7","Microglial cells":"300.1","Oligodendrocyte precursor cells":"456.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008157","HPA064664"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA008157":"AB_1858327","HPA064664":"AB_2685315"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.11e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"}},{"Gene":"TRIQK","Gene synonym":["C8orf83","DKFZp779L1068","LOC286144","PRO0845"],"Ensembl":"ENSG00000205133","Gene description":"Triple QxxK\/R motif containing","Uniprot":["Q629K1"],"Chromosome":"8","Position":"92883532-93017673","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"32.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skin - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"}},{"Gene":"TRMO","Gene synonym":["C9orf156","HSPC219"],"Ensembl":"ENSG00000136932","Gene description":"TRNA methyltransferase O","Uniprot":["Q9BU70"],"Chromosome":"9","Position":"97904489-97922516","Protein class":["Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["Methyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021281","HPA052197"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA021281":"AB_2670649","HPA052197":"AB_2681758"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.81e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"}},{"Gene":"TRMT2A","Gene synonym":["HTF9C"],"Ensembl":"ENSG00000099899","Gene description":"TRNA methyltransferase 2 homolog A","Uniprot":["Q8IZ69"],"Chromosome":"22","Position":"20111875-20117392","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["mRNA processing","tRNA processing"],"Molecular function":["Methyltransferase","RNA-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"82.3","Late spermatids":"238.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001077"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001077":"AB_1079092"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.99e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"}},{"Gene":"TRMU","Gene synonym":["FLJ10140","MTO2","MTU1","TRMT"],"Ensembl":"ENSG00000100416","Gene description":"TRNA mitochondrial 2-thiouridylase","Uniprot":["O75648"],"Chromosome":"22","Position":"46330875-46357340","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["tRNA processing"],"Molecular function":["RNA-binding","Transferase","tRNA-binding"],"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000824","HPA035273","HPA043300"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA000824":"AB_2732393","HPA035273":"AB_10602901","HPA043300":"AB_2678415"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.04e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.86e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.63e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-3"}},{"Gene":"TRO","Gene synonym":["KIAA1114","MAGE-D3","MAGED3"],"Ensembl":"ENSG00000067445","Gene description":"Trophinin","Uniprot":["Q12816"],"Chromosome":"X","Position":"54920462-54931431","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"31.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"9.2","Excitatory neurons":"14.4","Granulosa cells":"12.4","Inhibitory neurons":"19.6","Oligodendrocyte precursor cells":"16.4","Oligodendrocytes":"8.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"11.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"2.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"74.2"},"RNA tissue cell type enrichment":["Liver - Hepatocytes","Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000537"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA000537":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.41e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.93e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"}},{"Gene":"TRPA1","Gene synonym":["ANKTM1"],"Ensembl":"ENSG00000104321","Gene description":"Transient receptor potential cation channel subfamily A member 1","Uniprot":["O75762"],"Chromosome":"8","Position":"72019917-72075584","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"9.2","stomach 1":"10.3","urinary bladder":"27.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"15.1","Excitatory neurons":"4.9","Fibroblasts":"6.1","Intestinal goblet cells":"32.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"2.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"6.6"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.57e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"}},{"Gene":"TRPC1","Gene synonym":["HTRP-1"],"Ensembl":"ENSG00000144935","Gene description":"Transient receptor potential cation channel subfamily C member 1","Uniprot":["P48995"],"Chromosome":"3","Position":"142724034-142807888","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Astrocytes":"90.8","Excitatory neurons":"142.4","Granulosa cells":"89.9","Inhibitory neurons":"180.2","Microglial cells":"48.3","Oligodendrocyte precursor cells":"148.3","Oligodendrocytes":"155.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009387","HPA021130"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB009387":"AB_2240941","HPA021130":"AB_1858361"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.72e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"}},{"Gene":"TRPC3","Gene synonym":[],"Ensembl":"ENSG00000138741","Gene description":"Transient receptor potential cation channel subfamily C member 3","Uniprot":["Q13507"],"Chromosome":"4","Position":"121874481-121952060","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":["Disease variant","Neurodegeneration","Spinocerebellar ataxia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"10.4","pituitary gland":"7.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"31.0","Excitatory neurons":"17.8","Inhibitory neurons":"80.1","Oligodendrocyte precursor cells":"32.3","Rod photoreceptor cells":"53.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"57.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-3"}},{"Gene":"TRPC4","Gene synonym":["HTRP4","TRP4"],"Ensembl":"ENSG00000133107","Gene description":"Transient receptor potential cation channel subfamily C member 4","Uniprot":["Q9UBN4"],"Chromosome":"13","Position":"37632063-37869802","Protein class":["Plasma proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"11.9","seminal vesicle":"9.0","smooth muscle":"12.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Inhibitory neurons":"130.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"thyroid cancer":"9.5"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"43.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"}},{"Gene":"TRPC4AP","Gene synonym":["C20orf188","dJ756N5.2","DKFZp586C1223","DKFZP727M231","PPP1R158","TRRP4AP"],"Ensembl":"ENSG00000100991","Gene description":"Transient receptor potential cation channel subfamily C member 4 associated protein","Uniprot":["Q8TEL6"],"Chromosome":"20","Position":"35002404-35092807","Protein class":["Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"130.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051197","HPA065061"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA051197":"AB_2681384","HPA065061":"AB_2685416"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.25e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"}},{"Gene":"TRPC5","Gene synonym":["PPP1R159"],"Ensembl":"ENSG00000072315","Gene description":"Transient receptor potential cation channel subfamily C member 5","Uniprot":["Q9UL62"],"Chromosome":"X","Position":"111768011-112082776","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"3.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"45.5","Inhibitory neurons":"77.1","Oligodendrocytes":"36.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"23","RNA cancer specific FPKM":{"testis cancer":"0.8","thyroid cancer":"2.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TRPC6","Gene synonym":["FSGS2","TRP6"],"Ensembl":"ENSG00000137672","Gene description":"Transient receptor potential cation channel subfamily C member 6","Uniprot":["Q9Y210"],"Chromosome":"11","Position":"101451564-101872562","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"13.3","placenta":"20.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"19.0","Inhibitory neurons":"45.9","Microglial cells":"11.9","Smooth muscle cells":"20.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"eosinophil":"2.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"1.6","testis cancer":"2.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045098"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045098":"AB_10959600"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"}},{"Gene":"TRPC7","Gene synonym":[],"Ensembl":"ENSG00000069018","Gene description":"Transient receptor potential cation channel subfamily C member 7","Uniprot":["Q9HCX4"],"Chromosome":"5","Position":"136212745-136365545","Protein class":["Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"5.3","Enteroendocrine cells":"3.5","Inhibitory neurons":"9.9","Proximal tubular cells":"5.4","Spermatocytes":"3.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022592","HPA031126"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022592":null,"HPA031126":"AB_10603221"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TRPM1","Gene synonym":["CSNB1C","LTRPC1","MLSN1"],"Ensembl":"ENSG00000134160","Gene description":"Transient receptor potential cation channel subfamily M member 1","Uniprot":["Q7Z4N2"],"Chromosome":"15","Position":"31001061-31161273","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport","Vision"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Congenital stationary night blindness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"retina":"9.4","skin 1":"4.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Bipolar cells":"588.4","Melanocytes":"229.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"179","RNA cancer specific FPKM":{"melanoma":"14.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"141","RNA cell line specific nTPM":{"skin cancer":"27.3"},"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Skin - Melanocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014779","HPA071139"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Golgi apparatus","Plasma membrane"],"Antibody RRID":{"HPA014779":"AB_2669090","HPA071139":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"}},{"Gene":"TRPM2","Gene synonym":["EREG1","KNP3","LTRPC2","NUDT9H","NUDT9L1","TRPC7"],"Ensembl":"ENSG00000142185","Gene description":"Transient receptor potential cation channel subfamily M member 2","Uniprot":["O94759"],"Chromosome":"21","Position":"44350163-44443081","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Sodium transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Sodium channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"28.2","brain":"26.4","lymphoid tissue":"18.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"25.6","Excitatory neurons":"51.9","Hofbauer cells":"17.2","Inhibitory neurons":"44.2","Macrophages":"19.3","Microglial cells":"26.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"7.8","plasmacytoid DC":"15.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"15.5","monocytes":"7.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"43.8"},"RNA tissue cell type enrichment":["Adipose visceral - Macrophages","Kidney - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035260"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035260":"AB_2674540"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.28e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.39e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.59e-4"}},{"Gene":"TRPM3","Gene synonym":["GON-2","KIAA1616","LTRPC3"],"Ensembl":"ENSG00000083067","Gene description":"Transient receptor potential cation channel subfamily M member 3","Uniprot":["Q9HCF6"],"Chromosome":"9","Position":"70529060-71446904","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"choroid plexus":"801.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"876.8","Excitatory neurons":"384.1","Inhibitory neurons":"182.7","Muller glia cells":"158.4","Oligodendrocyte precursor cells":"101.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Brain cancer":"7.2","Rhabdoid":"11.8","skin cancer":"4.4"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Kidney - Proximal tubular cells","Pancreas - Beta cells","Prostate - Fibroblasts","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072650","HPA074393"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA072650":null,"HPA074393":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"}},{"Gene":"TRPM4","Gene synonym":["FLJ20041"],"Ensembl":"ENSG00000130529","Gene description":"Transient receptor potential cation channel subfamily M member 4","Uniprot":["Q8TD43"],"Chromosome":"19","Position":"49157741-49211836","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Adaptive immunity","Immunity","Ion transport","Transport"],"Molecular function":["Calmodulin-binding","Ion channel"],"Disease involvement":["Disease variant","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"159.6","Hepatocytes":"91.2","Intestinal goblet cells":"84.8","Prostatic glandular cells":"87.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"prostate cancer":"85.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"3.3","granulocytes":"2.8","monocytes":"4.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041169"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA041169":"AB_2677343"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.88e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.53e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"}},{"Gene":"TRPM5","Gene synonym":["LTRPC5","MTR1"],"Ensembl":"ENSG00000070985","Gene description":"Transient receptor potential cation channel subfamily M member 5","Uniprot":["Q9NZQ8"],"Chromosome":"11","Position":"2404515-2423045","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor","Voltage-gated channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"1.8","intestine":"3.3","pancreas":"2.4","seminal vesicle":"1.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Distal enterocytes":"10.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"1.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"1.1"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 56: Neurons - Neuronal signaling","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"}},{"Gene":"TRPM6","Gene synonym":["CHAK2","FLJ22628","HOMG","HSH"],"Ensembl":"ENSG00000119121","Gene description":"Transient receptor potential cation channel subfamily M member 6","Uniprot":["Q9BX84"],"Chromosome":"9","Position":"74722495-74888094","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"6.6","intestine":"16.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Distal enterocytes":"66.3","Glandular and luminal cells":"28.2","Microglial cells":"38.3","Oligodendrocytes":"76.5","Proximal enterocytes":"19.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"1.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"23.1","neutrophil":"7.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"41","RNA blood lineage specific nTPM":{"granulocytes":"23.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"2.8"},"RNA tissue cell type enrichment":["Kidney - Intercalated cells","Skeletal muscle - Endothelial cells","Skin - Outer root sheath cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"}},{"Gene":"TRPM7","Gene synonym":["CHAK1","LTRPC7","TRP-PLIK"],"Ensembl":"ENSG00000092439","Gene description":"Transient receptor potential cation channel subfamily M member 7","Uniprot":["Q96QT4"],"Chromosome":"15","Position":"50552473-50686797","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Necrosis","Transport"],"Molecular function":["Calcium channel","Ion channel","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Amyotrophic lateral sclerosis","Neurodegeneration","Parkinsonism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"108.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"120.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035522","HPA052173"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA035522":null,"HPA052173":"AB_2681749"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"}},{"Gene":"TRPM8","Gene synonym":[],"Ensembl":"ENSG00000144481","Gene description":"Transient receptor potential cation channel subfamily M member 8","Uniprot":["Q7Z2W7"],"Chromosome":"2","Position":"233917373-234019522","Protein class":["FDA approved drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Ion transport","Sensory transduction","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"57","RNA tissue specific nTPM":{"liver":"31.5","prostate":"80.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Hepatocytes":"37.9","Prostatic glandular cells":"88.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"27","RNA cancer specific FPKM":{"prostate cancer":"72.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Kidney cancer":"7.1","Myeloma":"8.3","prostate cancer":"13.6","skin cancer":"16.9"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"}},{"Gene":"TRPV1","Gene synonym":["VR1"],"Ensembl":"ENSG00000196689","Gene description":"Transient receptor potential cation channel subfamily V member 1","Uniprot":["Q8NER1"],"Chromosome":"17","Position":"3565444-3609411","Protein class":["FDA approved drug targets","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Ion channel"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"24.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"19.6","Oligodendrocytes":"17.7","Rod photoreceptor cells":"23.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"}},{"Gene":"TRPV2","Gene synonym":["VRL","VRL-1","VRL1"],"Ensembl":"ENSG00000187688","Gene description":"Transient receptor potential cation channel subfamily V member 2","Uniprot":["Q9Y5S1"],"Chromosome":"17","Position":"16415571-16437003","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"43.0","Hofbauer cells":"49.5","Macrophages":"34.3","Melanocytes":"52.2","NK-cells":"31.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"melanoma":"59.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"71.7"},"RNA tissue cell type enrichment":["Breast - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044993"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA044993":"AB_10960889"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.19e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.53e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"TRPV3","Gene synonym":["VRL3"],"Ensembl":"ENSG00000167723","Gene description":"Transient receptor potential cation channel subfamily V member 3","Uniprot":["Q8NET8"],"Chromosome":"17","Position":"3510502-3557812","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel"],"Disease involvement":["Disease variant","FDA approved drug targets","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"5.2","skin 1":"4.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"13.4","Plasma cells":"10.7","Proximal enterocytes":"22.2","Schwann cells":"15.4","Skeletal myocytes":"8.9","Suprabasal keratinocytes":"13.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"1.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"3.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069550"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"HPA069550":"AB_2686149"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"}},{"Gene":"TRPV4","Gene synonym":["CMT2C","OTRPC4","TRP12","VR-OAC","VRL-2","VROAC"],"Ensembl":"ENSG00000111199","Gene description":"Transient receptor potential cation channel subfamily V member 4","Uniprot":["Q9HBA0"],"Chromosome":"12","Position":"109783087-109833406","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Ion channel"],"Disease involvement":["Charcot-Marie-Tooth disease","Disease variant","Dwarfism","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"50.8","salivary gland":"19.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"15.8","Cholangiocytes":"15.4","Cytotrophoblasts":"19.6","Ionocytes":"19.4","Respiratory ciliated cells":"30.4","Salivary duct cells":"15.2","Syncytiotrophoblasts":"19.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"hippocampal formation":"4.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"11.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Lung - Respiratory ciliated cells","Prostate - Prostate basal glandular cells","Skin - Eccrine sweat gland cells","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007150"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007150":"AB_1080393"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.10e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"}},{"Gene":"TRPV5","Gene synonym":["CaT2","ECAC1"],"Ensembl":"ENSG00000127412","Gene description":"Transient receptor potential cation channel subfamily V member 5","Uniprot":["Q9NQA5"],"Chromosome":"7","Position":"142908101-142933746","Protein class":["Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"1.1","kidney":"4.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Oligodendrocytes":"14.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063175"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063175":"AB_2684954"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-3"}},{"Gene":"TRPV6","Gene synonym":["CaT1","ECAC2"],"Ensembl":"ENSG00000165125","Gene description":"Transient receptor potential cation channel subfamily V member 6","Uniprot":["Q9H1D0"],"Chromosome":"7","Position":"142871208-142885745","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters","Voltage-gated ion channels"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"38.3","prostate":"23.5","salivary gland":"69.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"84.9","Late spermatids":"41.5","Prostatic glandular cells":"54.3","Serous glandular cells":"59.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"prostate cancer":"16.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"7.6","prostate cancer":"10.2"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Liver - Cholangiocyte","Prostate - Prostate glandular cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062864"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA062864":"AB_2684885"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"}},{"Gene":"TRUB1","Gene synonym":["PUS4"],"Ensembl":"ENSG00000165832","Gene description":"TruB pseudouridine synthase family member 1","Uniprot":["Q8WWH5"],"Chromosome":"10","Position":"114938195-114977676","Protein class":["Predicted intracellular proteins"],"Biological process":["mRNA processing","tRNA processing"],"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"82.0","Theca cells":"60.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037914","HPA057552"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA037914":"AB_10672399","HPA057552":"AB_2683465"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"TSBP1","Gene synonym":["C6orf10","TSBP"],"Ensembl":"ENSG00000204296","Gene description":"Testis expressed basic protein 1","Uniprot":["Q5SRN2"],"Chromosome":"6","Position":"32288526-32371912","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"61","RNA tissue specific nTPM":{"testis":"35.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Early spermatids":"510.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047479","HPA057426"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA047479":null,"HPA057426":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TSC1","Gene synonym":["hamartin","KIAA0243","LAM","TSC"],"Ensembl":"ENSG00000165699","Gene description":"TSC complex subunit 1","Uniprot":["Q92574"],"Chromosome":"9","Position":"132891348-132946874","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"412.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011568","CAB012481","HPA074132"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB011568":"AB_732752","CAB012481":null,"HPA074132":"AB_2686666"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.01e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"}},{"Gene":"TSC2","Gene synonym":["LAM","PPP1R160","TSC4","tuberin"],"Ensembl":"ENSG00000103197","Gene description":"TSC complex subunit 2","Uniprot":["P49815"],"Chromosome":"16","Position":"2047967-2089491","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"144.6","Horizontal cells":"126.3","Rod photoreceptor cells":"161.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002225","HPA030409","HPA049679"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002225":"AB_564043","HPA030409":"AB_10602483","HPA049679":"AB_2680848"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.06e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"}},{"Gene":"TSEN2","Gene synonym":["MGC2776","SEN2","SEN2L"],"Ensembl":"ENSG00000154743","Gene description":"TRNA splicing endonuclease subunit 2","Uniprot":["Q8NCE0"],"Chromosome":"3","Position":"12484421-12541549","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","tRNA processing"],"Molecular function":["Lyase"],"Disease involvement":["Neurodegeneration","Pontocerebellar hypoplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"59.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027120","HPA027125","HPA027268"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"HPA027120":"AB_10600197","HPA027125":"AB_10601896","HPA027268":"AB_10601347"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.49e-4"}},{"Gene":"TSEN54","Gene synonym":["SEN54","SEN54L"],"Ensembl":"ENSG00000182173","Gene description":"TRNA splicing endonuclease subunit 54","Uniprot":["Q7Z6J9"],"Chromosome":"17","Position":"75515944-75524735","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["mRNA processing","tRNA processing"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Pontocerebellar hypoplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"88.0","NK-cells":"153.1","T-cells":"83.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024543","HPA053097"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA024543":null,"HPA053097":"AB_2682043"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.06e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.62e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.78e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.54e-4"}},{"Gene":"TSFM","Gene synonym":["EF-TS","EF-Tsmt"],"Ensembl":"ENSG00000123297","Gene description":"Ts translation elongation factor, mitochondrial","Uniprot":["P43897"],"Chromosome":"12","Position":"57782761-57808071","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Elongation factor"],"Disease involvement":["Cardiomyopathy","Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"29.0","Erythroid cells":"12.1","Late spermatids":"34.0","Plasma cells":"12.7","Squamous epithelial cells":"15.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006204"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9200","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA006204":"AB_1080405"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.82e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"TSHR","Gene synonym":["LGR3"],"Ensembl":"ENSG00000165409","Gene description":"Thyroid stimulating hormone receptor","Uniprot":["P16473"],"Chromosome":"14","Position":"80954989-81146306","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","Congenital hypothyroidism","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"thyroid gland":"273.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"6.9","Inhibitory neurons":"12.1","Langerhans cells":"7.2","Oligodendrocytes":"8.9","Plasma cells":"15.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"116","RNA cancer specific FPKM":{"thyroid cancer":"100.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"naive B-cell":"1.7","T-reg":"6.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"1.7","T-cells":"6.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"10.3"},"RNA tissue cell type enrichment":["Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"hypothalamus":"1.3"},"Antibody":["CAB000473"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000473":"AB_2303782"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"}},{"Gene":"TSLP","Gene synonym":[],"Ensembl":"ENSG00000145777","Gene description":"Thymic stromal lymphopoietin","Uniprot":["Q969D9"],"Chromosome":"5","Position":"111070062-111078026","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"11.5","urinary bladder":"12.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal respiratory cells":"103.5","Basal squamous epithelial cells":"213.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056350"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":38400,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA056350":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"}},{"Gene":"TSN","Gene synonym":["BCLF-1","REHF-1","TRSLN"],"Ensembl":"ENSG00000211460","Gene description":"Translin","Uniprot":["Q15631"],"Chromosome":"2","Position":"121737103-121767853","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["DNA-binding","Endonuclease","Hydrolase","Nuclease","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059561"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm","Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA059561":"AB_2684063"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.05e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-1"}},{"Gene":"TSNARE1","Gene synonym":["FLJ31164"],"Ensembl":"ENSG00000171045","Gene description":"T-SNARE domain containing 1","Uniprot":["Q96NA8"],"Chromosome":"8","Position":"142212080-142403182","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"26.3","Inhibitory neurons":"22.5","Oligodendrocyte precursor cells":"20.2","Oligodendrocytes":"23.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074249"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA074249":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.33e-4"}},{"Gene":"TSPAN1","Gene synonym":["NET-1","TSPAN-1"],"Ensembl":"ENSG00000117472","Gene description":"Tetraspanin 1","Uniprot":["O60635"],"Chromosome":"1","Position":"46175073-46185962","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"593.8","kidney":"244.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"715.4","Distal enterocytes":"1930.5","Intestinal goblet cells":"697.9","Ionocytes":"1049.6","Late spermatids":"818.3","Paneth cells":"818.9","Respiratory ciliated cells":"1514.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"455.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"57","RNA blood cell specific nTPM":{"plasmacytoid DC":"5.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"57","RNA blood lineage specific nTPM":{"dendritic cells":"5.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"212.0"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Lung - Respiratory ciliated cells","Stomach - Gastric mucous cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011909"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA011909":"AB_2668565"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.28e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"}},{"Gene":"TSPAN10","Gene synonym":["OCSP"],"Ensembl":"ENSG00000182612","Gene description":"Tetraspanin 10","Uniprot":[],"Chromosome":"17","Position":"81637171-81648749","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"13.8","Melanocytes":"17.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"melanoma":"32.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"skin cancer":"23.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"}},{"Gene":"TSPAN11","Gene synonym":[],"Ensembl":"ENSG00000110900","Gene description":"Tetraspanin 11","Uniprot":["A1L157"],"Chromosome":"12","Position":"30926428-30996602","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"25.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"11.4","Melanocytes":"7.0","Oligodendrocyte precursor cells":"26.0","Schwann cells":"19.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"11.7","Neuroblastoma":"12.0","testis cancer":"11.2"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Skeletal muscle - Fibroblasts","Skin - Fibroblast_1","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066789"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA066789":"AB_2685723"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.28e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.43e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"}},{"Gene":"TSPAN12","Gene synonym":["NET-2","TM4SF12"],"Ensembl":"ENSG00000106025","Gene description":"Tetraspanin 12","Uniprot":["O95859"],"Chromosome":"7","Position":"120787320-120858402","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"91.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"84.5","Collecting duct cells":"94.5","Distal tubular cells":"143.0","Glandular and luminal cells":"92.2","Proximal tubular cells":"91.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"44.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Liver - Hepatocytes","Skin - Endothelial cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051570","HPA058244"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":["Microtubules"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA051570":null,"HPA058244":"AB_2683652"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"}},{"Gene":"TSPAN13","Gene synonym":["NET-6","TM4SF13"],"Ensembl":"ENSG00000106537","Gene description":"Tetraspanin 13","Uniprot":["O95857"],"Chromosome":"7","Position":"16753755-16784536","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"299.3","Alveolar cells type 1":"434.3","Cytotrophoblasts":"294.0","dendritic cells":"375.9","Intestinal goblet cells":"344.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"99.6","plasmacytoid DC":"231.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"42","RNA blood lineage specific nTPM":{"B-cells":"99.6","dendritic cells":"231.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Lung - Alveolar cells type 1","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007426"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA007426":"AB_10603137"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.56e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.94e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.43e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"}},{"Gene":"TSPAN14","Gene synonym":["DC-TM4F2","MGC11352","TM4SF14"],"Ensembl":"ENSG00000108219","Gene description":"Tetraspanin 14","Uniprot":["Q8NG11"],"Chromosome":"10","Position":"80454166-80533124","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014773","HPA057174"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA014773":"AB_2208670","HPA057174":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.56e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-3"}},{"Gene":"TSPAN15","Gene synonym":["NET-7","TM4SF15"],"Ensembl":"ENSG00000099282","Gene description":"Tetraspanin 15","Uniprot":["O95858"],"Chromosome":"10","Position":"69451465-69507666","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"110.9","Ductal cells":"110.8","Exocrine glandular cells":"157.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"MAIT T-cell":"19.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"19.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044657","HPA071160"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nuclear bodies","Plasma membrane"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA044657":"AB_10967927","HPA071160":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.00e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-3"}},{"Gene":"TSPAN16","Gene synonym":["TM-8","TM4-B","TM4SF16"],"Ensembl":"ENSG00000130167","Gene description":"Tetraspanin 16","Uniprot":["Q9UKR8"],"Chromosome":"19","Position":"11296139-11326996","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"26","RNA tissue specific nTPM":{"testis":"134.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Late spermatids":"4959.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"basophil":"16.6","eosinophil":"19.1","neutrophil":"37.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"granulocytes":"37.4"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076551"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA076551":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"}},{"Gene":"TSPAN17","Gene synonym":["FBX23","FBXO23","TM4SF17"],"Ensembl":"ENSG00000048140","Gene description":"Tetraspanin 17","Uniprot":["Q96FV3"],"Chromosome":"5","Position":"176647387-176659054","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"82.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030447"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030447":"AB_2673484"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"}},{"Gene":"TSPAN18","Gene synonym":["TSPAN"],"Ensembl":"ENSG00000157570","Gene description":"Tetraspanin 18","Uniprot":["Q96SJ8"],"Chromosome":"11","Position":"44726465-44932423","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"83.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"70.9","Cardiomyocytes":"19.7","Early spermatids":"20.4","Endothelial cells":"58.5","Proximal tubular cells":"18.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"28.8","testis cancer":"99.8"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Smooth muscle cells","Kidney - Proximal tubular cells","Liver - Vascular Endothelial cells","Prostate - Smooth muscle cells","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"}},{"Gene":"TSPAN19","Gene synonym":[],"Ensembl":"ENSG00000231738","Gene description":"Tetraspanin 19","Uniprot":["P0C672"],"Chromosome":"12","Position":"85014311-85036277","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"4.3","testis":"4.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"99.2","Ionocytes":"59.8","Respiratory ciliated cells":"209.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057066"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA057066":"AB_2683325"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-3"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TSPAN2","Gene synonym":["FLJ12082","TSN2","TSPAN-2"],"Ensembl":"ENSG00000134198","Gene description":"Tetraspanin 2","Uniprot":["O60636"],"Chromosome":"1","Position":"115048011-115089503","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"47.4","intestine":"55.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"32.8","NK-cells":"30.3","Pancreatic endocrine cells":"73.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"109.0","neutrophil":"109.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"109.8","NK-cells":"86.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"39.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Smooth muscle cells","Prostate - Smooth muscle cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"white matter":"842.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015640","HPA073306"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015640":"AB_1858405","HPA073306":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.89e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.48e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-3"}},{"Gene":"TSPAN3","Gene synonym":["TM4-A","TM4SF8","TSPAN-3"],"Ensembl":"ENSG00000140391","Gene description":"Tetraspanin 3","Uniprot":["O60637"],"Chromosome":"15","Position":"77041404-77083984","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"617.0","Muller glia cells":"475.3","Thymic epithelial cells":"498.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"481.0","naive B-cell":"488.1","plasmacytoid DC":"313.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"488.1","dendritic cells":"313.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Lung - Alveolar cells type 2","Skin - Fibroblast_1","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015996"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA015996":"AB_1858406"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"}},{"Gene":"TSPAN31","Gene synonym":["SAS"],"Ensembl":"ENSG00000135452","Gene description":"Tetraspanin 31","Uniprot":["Q12999"],"Chromosome":"12","Position":"57738013-57750219","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"54.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030758","HPA057489"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cytokinetic bridge","Cytosol"],"Antibody RRID":{"HPA030758":null,"HPA057489":"AB_2683447"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"}},{"Gene":"TSPAN32","Gene synonym":["PHEMX","TSSC6"],"Ensembl":"ENSG00000064201","Gene description":"Tetraspanin 32","Uniprot":["Q96QS1"],"Chromosome":"11","Position":"2301997-2318204","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"19.9","heart muscle":"11.4","lymphoid tissue":"5.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"14.9","Erythroid cells":"22.0","granulocytes":"15.6","Langerhans cells":"24.8","monocytes":"37.1","NK-cells":"68.3","T-cells":"20.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"8.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Heart muscle - Cardiomyocytes","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024135"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA024135":"AB_1858409"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"}},{"Gene":"TSPAN33","Gene synonym":["MGC50844","Penumbra"],"Ensembl":"ENSG00000158457","Gene description":"Tetraspanin 33","Uniprot":["Q86UF1"],"Chromosome":"7","Position":"129144707-129169699","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"64.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"39.5","Langerhans cells":"107.1","Macrophages":"32.7","Peritubular cells":"31.7","Proximal tubular cells":"47.2","Schwann cells":"72.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"1.1","naive B-cell":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"26.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020357"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA020357":"AB_1858410"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.88e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.74e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"}},{"Gene":"TSPAN4","Gene synonym":["NAG-2","TETRASPAN","TM4SF7","TSPAN-4"],"Ensembl":"ENSG00000214063","Gene description":"Tetraspanin 4","Uniprot":["O14817"],"Chromosome":"11","Position":"842812-867116","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"199.2","Hofbauer cells":"221.7","Leydig cells":"176.1","Melanocytes":"170.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"classical monocyte":"146.4","intermediate monocyte":"143.5","myeloid DC":"101.2","NK-cell":"95.6","non-classical monocyte":"39.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"101.2","monocytes":"146.4","NK-cells":"95.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"cerebellum":"142.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.91e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"}},{"Gene":"TSPAN5","Gene synonym":["NET-4","TM4SF9","Tspan-5"],"Ensembl":"ENSG00000168785","Gene description":"Tetraspanin 5","Uniprot":["P62079"],"Chromosome":"4","Position":"98470367-98658611","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"62.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"357.0","Inhibitory neurons":"242.8","Microglial cells":"190.6","Oligodendrocytes":"554.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"37","RNA blood lineage specific nTPM":{"B-cells":"3.0","NK-cells":"3.8","T-cells":"6.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Skin - Keratinocyte (other)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079522"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Plasma membrane","Actin filaments"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA079522":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.83e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.56e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"}},{"Gene":"TSPAN6","Gene synonym":["T245","TM4SF6","TSPAN-6"],"Ensembl":"ENSG00000000003","Gene description":"Tetraspanin 6","Uniprot":["O43657"],"Chromosome":"X","Position":"100627108-100639991","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"327.0","Granulosa cells":"665.3","Late spermatids":"1778.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"2.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004109"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Cell Junctions","Cytosol"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"HPA004109":"AB_1080301"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-3"}},{"Gene":"TSPAN7","Gene synonym":["A15","CD231","DXS1692E","MRX58","MXS1","TALLA-1","TM4SF2"],"Ensembl":"ENSG00000156298","Gene description":"Tetraspanin 7","Uniprot":["P41732"],"Chromosome":"X","Position":"38561542-38688920","Protein class":["CD markers","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"542.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"266.3","Cone photoreceptor cells":"158.5","Endothelial cells":"156.3","Excitatory neurons":"212.6","Inhibitory neurons":"243.5","Oligodendrocyte precursor cells":"338.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"71.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"61.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Heart muscle - Endothelial cells","Liver - Sinusoid Endothelial cells","Prostate - Endothelial cells","Testis - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003140","CAB062566","CAB068245"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB062566":"AB_2665608","CAB068245":"AB_2665609","HPA003140":"AB_1078454"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.40e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.48e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"}},{"Gene":"TSPAN8","Gene synonym":["CO-029","TM4SF3"],"Ensembl":"ENSG00000127324","Gene description":"Tetraspanin 8","Uniprot":["P19075"],"Chromosome":"12","Position":"71125085-71441898","Protein class":["Cancer-related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"951.1","stomach 1":"631.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"2738.1","Ductal cells":"883.1","Enteroendocrine cells":"847.4","Intestinal goblet cells":"895.4","Paneth cells":"2018.1","Proximal enterocytes":"3421.1","Undifferentiated cells":"1543.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"283.9","pancreatic cancer":"156.9","stomach cancer":"194.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bile duct cancer":"218.4","colorectal cancer":"632.1","Gastric cancer":"475.3","pancreatic cancer":"331.8"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Prostate - Prostate glandular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022273","CAB026009","HPA044337"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB026009":null,"HPA022273":null,"HPA044337":"AB_2678899"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.66e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.36e-5"}},{"Gene":"TSPAN9","Gene synonym":["NET-5"],"Ensembl":"ENSG00000011105","Gene description":"Tetraspanin 9","Uniprot":["O75954"],"Chromosome":"12","Position":"3077355-3286564","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"128.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"86.5","Extravillous trophoblasts":"116.8","Syncytiotrophoblasts":"75.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"96.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"cerebellum":"58.1"},"Antibody":["HPA014002"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA014002":"AB_2304038"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.67e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"}},{"Gene":"TSPO","Gene synonym":["BZRP","DBI","IBP","MBR","mDRC","PBR","pk18","PKBS"],"Ensembl":"ENSG00000100300","Gene description":"Translocator protein","Uniprot":["B1AH88","P30536"],"Chromosome":"22","Position":"43151547-43163242","Protein class":["Cancer-related genes","FDA approved drug targets","Predicted membrane proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"690.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"1377.4","Suprabasal keratinocytes":"1587.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011232","HPA046260","HPA072304"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"CAB011232":null,"HPA046260":null,"HPA072304":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.61e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-3"}},{"Gene":"TSPO2","Gene synonym":["BZRPL1","dJ34B21.2"],"Ensembl":"ENSG00000112212","Gene description":"Translocator protein 2","Uniprot":["Q5TGU0"],"Chromosome":"6","Position":"41042467-41044337","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"30","RNA tissue specific nTPM":{"bone marrow":"50.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"72","RNA single cell type specific nTPM":{"Erythroid cells":"156.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"2.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060691","HPA066996"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA060691":null,"HPA066996":"AB_2685761"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"}},{"Gene":"TSSK1B","Gene synonym":["FKSG81","SPOGA4","STK22D","TSSK1"],"Ensembl":"ENSG00000212122","Gene description":"Testis specific serine kinase 1B","Uniprot":["Q9BXA7"],"Chromosome":"5","Position":"113432553-113434989","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"224","RNA tissue specific nTPM":{"testis":"53.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"181","RNA single cell type specific nTPM":{"Early spermatids":"389.5","Late spermatids":"1107.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027827"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 69: BICR 18 - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027827":"AB_10603138"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TSSK2","Gene synonym":["FLJ38613","SPOGA2","STK22B"],"Ensembl":"ENSG00000206203","Gene description":"Testis specific serine kinase 2","Uniprot":["Q96PF2"],"Chromosome":"22","Position":"19131308-19132622","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"231","RNA tissue specific nTPM":{"testis":"135.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"126","RNA single cell type specific nTPM":{"Early spermatids":"1147.9","Late spermatids":"3451.8"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TSSK3","Gene synonym":["SPOGA3","STK22C"],"Ensembl":"ENSG00000162526","Gene description":"Testis specific serine kinase 3","Uniprot":["Q96PN8"],"Chromosome":"1","Position":"32351521-32364312","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"12.7","testis":"34.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"1266.5"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebellum":"2.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037516"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA037516":"AB_2675517"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"}},{"Gene":"TSSK4","Gene synonym":["C14orf20","STK22E"],"Ensembl":"ENSG00000139908","Gene description":"Testis specific serine kinase 4","Uniprot":["Q6SA08"],"Chromosome":"14","Position":"24205696-24208362","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"testis":"38.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Early spermatids":"309.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060660","HPA077103"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA060660":"AB_2684339","HPA077103":"AB_2732332"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"}},{"Gene":"TSSK6","Gene synonym":["CT72","FLJ24002","SSTK"],"Ensembl":"ENSG00000178093","Gene description":"Testis specific serine kinase 6","Uniprot":["Q9BXA6"],"Chromosome":"19","Position":"19512418-19515548","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"102","RNA tissue specific nTPM":{"testis":"167.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Late spermatids":"8873.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-2"}},{"Gene":"TTC13","Gene synonym":["FLJ22584"],"Ensembl":"ENSG00000143643","Gene description":"Tetratricopeptide repeat domain 13","Uniprot":["Q8NBP0"],"Chromosome":"1","Position":"230906243-230978875","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"41.4","Excitatory neurons":"69.9","Inhibitory neurons":"75.0","Microglial cells":"54.7","Oligodendrocyte precursor cells":"40.0","Oligodendrocytes":"66.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018022","HPA051558"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA018022":"AB_2211524","HPA051558":"AB_2681534"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.66e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.59e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-3"}},{"Gene":"TTC14","Gene synonym":["FLJ00166","KIAA1980"],"Ensembl":"ENSG00000163728","Gene description":"Tetratricopeptide repeat domain 14","Uniprot":["Q96N46"],"Chromosome":"3","Position":"180602163-180617828","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009295"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA009295":"AB_1858425"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"}},{"Gene":"TTC17","Gene synonym":["FLJ10890"],"Ensembl":"ENSG00000052841","Gene description":"Tetratricopeptide repeat domain 17","Uniprot":["Q96AE7"],"Chromosome":"11","Position":"43358920-43494933","Protein class":["Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"201.6","Inhibitory neurons":"198.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038508"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA038508":"AB_10671744"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.75e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"}},{"Gene":"TTC28","Gene synonym":["KIAA1043"],"Ensembl":"ENSG00000100154","Gene description":"Tetratricopeptide repeat domain 28","Uniprot":["Q96AY4"],"Chromosome":"22","Position":"27978014-28679865","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"282.5","Excitatory neurons":"167.0","Inhibitory neurons":"283.1","Microglial cells":"323.8","Oligodendrocyte precursor cells":"305.2","Oligodendrocytes":"109.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001080"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytokinetic bridge","Mitotic spindle","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Microtubules","Cytokinetic bridge","Mitotic spindle"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA001080":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.30e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.65e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.21e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"}},{"Gene":"TTC3","Gene synonym":["DCRR1","RNF105","TPRD","TPRDI","TPRDII","TPRDIII"],"Ensembl":"ENSG00000182670","Gene description":"Tetratricopeptide repeat domain 3","Uniprot":["P53804"],"Chromosome":"21","Position":"37073226-37203112","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016810","HPA023964","HPA036304"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA016810":"AB_1858434","HPA023964":"AB_1858435","HPA036304":"AB_2675049"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"}},{"Gene":"TTC33","Gene synonym":["OSRF"],"Ensembl":"ENSG00000113638","Gene description":"Tetratricopeptide repeat domain 33","Uniprot":["Q6PID6"],"Chromosome":"5","Position":"40512333-40755963","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038252","HPA038253"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"HPA038252":"AB_10674551","HPA038253":"AB_10671739"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-3"}},{"Gene":"TTC34","Gene synonym":[],"Ensembl":"ENSG00000215912","Gene description":"Tetratricopeptide repeat domain 34","Uniprot":["A8MYJ7"],"Chromosome":"1","Position":"2635976-2801717","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"5.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"5.8","Early spermatids":"23.6","Late spermatids":"25.4","Respiratory ciliated cells":"9.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066832"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066832":"AB_2685731"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-4"}},{"Gene":"TTC37","Gene synonym":["KIAA0372","THES"],"Ensembl":"ENSG00000198677","Gene description":"Tetratricopeptide repeat domain 37","Uniprot":["Q6PGP7"],"Chromosome":"5","Position":"95461755-95554977","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037905"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA037905":"AB_10673034"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.62e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-3"}},{"Gene":"TTC39A","Gene synonym":["C1orf34","DEME-6","KIAA0452"],"Ensembl":"ENSG00000085831","Gene description":"Tetratricopeptide repeat domain 39A","Uniprot":["Q5SRH9"],"Chromosome":"1","Position":"51287258-51345116","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"59.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"377.5","Late spermatids":"638.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"42","RNA blood cell specific nTPM":{"plasmacytoid DC":"31.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"42","RNA blood lineage specific nTPM":{"dendritic cells":"31.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"56.8"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Colon - Colon enterocytes","Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 2","Prostate - Prostate glandular cells","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028098","HPA043440"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA028098":"AB_10601705","HPA043440":"AB_2678483"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.05e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"}},{"Gene":"TTC39B","Gene synonym":["C9orf52","FLJ33868"],"Ensembl":"ENSG00000155158","Gene description":"Tetratricopeptide repeat domain 39B","Uniprot":["Q5VTQ0"],"Chromosome":"9","Position":"15163622-15307360","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"62.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"2.0","gdT-cell":"2.9","MAIT T-cell":"3.9","memory CD4 T-cell":"4.0","memory CD8 T-cell":"4.6","naive CD4 T-cell":"4.7","naive CD8 T-cell":"2.9","NK-cell":"6.3","T-reg":"3.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.0","NK-cells":"6.3","T-cells":"4.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063162"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA063162":"AB_2684952"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.64e-6"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.08e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"}},{"Gene":"TTI2","Gene synonym":["C8orf41","FLJ23263"],"Ensembl":"ENSG00000129696","Gene description":"TELO2 interacting protein 2","Uniprot":["Q6NXR4"],"Chromosome":"8","Position":"33473386-33513185","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"30.1","Spermatocytes":"36.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023523","HPA029823"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Centrosome"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA023523":"AB_1845776","HPA029823":"AB_10602337"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"}},{"Gene":"TTN","Gene synonym":["CMD1G","CMH9","CMPD4","FLJ32040","LGMD2J","MYLK5","TMD"],"Ensembl":"ENSG00000155657","Gene description":"Titin","Uniprot":["Q8WZ42"],"Chromosome":"2","Position":"178525989-178830802","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cardiomyopathy","Disease variant","Limb-girdle muscular dystrophy","Myofibrillar myopathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"167.2","skeletal muscle":"920.6","tongue":"369.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"80","RNA single cell type specific nTPM":{"Cardiomyocytes":"43212.8","Skeletal myocytes":"19345.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"head and neck cancer":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Lung - Alveolar cells type 2","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007042","CAB022682","HPA030048"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022682":null,"HPA007042":"AB_1080292","HPA030048":"AB_2732451"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"}},{"Gene":"TTYH1","Gene synonym":[],"Ensembl":"ENSG00000167614","Gene description":"Tweety family member 1","Uniprot":["Q9H313"],"Chromosome":"19","Position":"54415219-54436904","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Cell adhesion","Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"80.9","choroid plexus":"35.6","testis":"53.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"249.6","Bipolar cells":"135.4","Muller glia cells":"612.9","Oligodendrocytes":"92.1","Rod photoreceptor cells":"143.9","Schwann cells":"155.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"glioma":"63.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Skin - Eccrine sweat gland cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005725","HPA023617","HPA050655"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA005725":null,"HPA023617":"AB_10600836","HPA050655":"AB_2681204"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.64e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"}},{"Gene":"TTYH2","Gene synonym":["C17orf29"],"Ensembl":"ENSG00000141540","Gene description":"Tweety family member 2","Uniprot":["Q9BSA4"],"Chromosome":"17","Position":"74213571-74262020","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"214.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"44.6","Bipolar cells":"58.5","Langerhans cells":"64.8","Oligodendrocytes":"195.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"16.7","melanoma":"20.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"13.3","intermediate monocyte":"22.3","myeloid DC":"14.6","non-classical monocyte":"28.6","plasmacytoid DC":"18.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"18.2","monocytes":"28.6"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"29.5"},"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Heart muscle - Cardiomyocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.74e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"}},{"Gene":"TTYH3","Gene synonym":["KIAA1691"],"Ensembl":"ENSG00000136295","Gene description":"Tweety family member 3","Uniprot":["Q9C0H2"],"Chromosome":"7","Position":"2631986-2664802","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Chloride channel","Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"126.3","Kupffer cells":"59.0","Macrophages":"69.4","Melanocytes":"64.4","monocytes":"79.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"10.0","non-classical monocyte":"8.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"monocytes":"10.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053520"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053520":"AB_2682176"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"}},{"Gene":"TUBA8","Gene synonym":["TUBAL2"],"Ensembl":"ENSG00000183785","Gene description":"Tubulin alpha 8","Uniprot":["Q9NY65"],"Chromosome":"22","Position":"18110100-18146683","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"128.9","skeletal muscle":"332.2","tongue":"154.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"1.9","Excitatory neurons":"7.9","Horizontal cells":"1.9","Inhibitory neurons":"5.5","Oligodendrocyte precursor cells":"3.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"2.8","eosinophil":"2.7","neutrophil":"5.0","NK-cell":"10.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"5.0","NK-cells":"10.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"12.7"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"cerebellum":"54.7","olfactory bulb":"53.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043684","CAB046031","HPA063394"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"80000000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB046031":"AB_11124541","HPA043684":"AB_2678617","HPA063394":"AB_2685003"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-4"}},{"Gene":"TUBD1","Gene synonym":["FLJ12709","TUBD"],"Ensembl":"ENSG00000108423","Gene description":"Tubulin delta 1","Uniprot":["Q9UJT1"],"Chromosome":"17","Position":"59859479-59892945","Protein class":["FDA approved drug targets","Predicted intracellular proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":["Developmental protein"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004609","HPA023980","HPA027090"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004609":"AB_628416","HPA023980":"AB_1858456","HPA027090":"AB_1858457"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.04e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.00e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.06e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"}},{"Gene":"TUBE1","Gene synonym":["dJ142L7.2","FLJ22589","TUBE"],"Ensembl":"ENSG00000074935","Gene description":"Tubulin epsilon 1","Uniprot":["Q9UJT0"],"Chromosome":"6","Position":"112070663-112087529","Protein class":["FDA approved drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"210.6","Spermatocytes":"85.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032073","HPA032074"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA032073":"AB_10601773","HPA032074":"AB_10601216"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"}},{"Gene":"TUBG1","Gene synonym":["TUBG","TUBGCP1"],"Ensembl":"ENSG00000131462","Gene description":"Tubulin gamma 1","Uniprot":["P23258"],"Chromosome":"17","Position":"42609641-42615238","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","FDA approved drug targets","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"173.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"453.6","Erythroid cells":"245.6","Late spermatids":"660.5","Spermatocytes":"348.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004608"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004608":"AB_628417"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.99e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.48e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"}},{"Gene":"TUBGCP2","Gene synonym":["GCP2","SPBC97","Spc97p"],"Ensembl":"ENSG00000130640","Gene description":"Tubulin gamma complex associated protein 2","Uniprot":["Q9BSJ2"],"Chromosome":"10","Position":"133278635-133312337","Protein class":["Disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epilepsy","Intellectual disability","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037885"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm","Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA037885":"AB_10672397"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"}},{"Gene":"TUBGCP5","Gene synonym":["GCP5","KIAA1899"],"Ensembl":"ENSG00000275835","Gene description":"Tubulin gamma complex associated protein 5","Uniprot":["Q96RT8"],"Chromosome":"15","Position":"22983192-23039572","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039366","HPA040366"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039366":"AB_10673243","HPA040366":"AB_2676942"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.53e-3"}},{"Gene":"TUG1","Gene synonym":["FLJ20618","LINC00080","NCRNA00080"],"Ensembl":"ENSG00000253352","Gene description":"Taurine up-regulated 1","Uniprot":[],"Chromosome":"22","Position":"30969245-30979395","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.37e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.27e-4"}},{"Gene":"TUNAR","Gene synonym":["HI-LNC78","LINC00617","TUNA"],"Ensembl":"ENSG00000250366","Gene description":"TCL1 upstream neural differentiation-associated RNA","Uniprot":[],"Chromosome":"14","Position":"95876392-95925663","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"42.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"10.4","Endometrial stromal cells":"9.1","Excitatory neurons":"4.5","Glandular and luminal cells":"16.7","Horizontal cells":"15.4","Pancreatic endocrine cells":"5.2","Spermatogonia":"4.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"3.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Kidney cancer":"1.1","Leukemia":"3.5","lung cancer":"2.4","lymphoma":"1.5","Neuroblastoma":"3.4","ovarian cancer":"3.7","prostate cancer":"3.4","testis cancer":"4.6","thyroid cancer":"3.8","Uterine cancer":"1.8"},"RNA tissue cell type enrichment":["Pancreas - Alpha cells","Pancreas - Beta cells","Testis - Spermatogonia","Thyroid - Parafollicular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"TUSC3","Gene synonym":["MagT2","MGC13453","MRT22","MRT7","N33","OST3A","SLC58A2"],"Ensembl":"ENSG00000104723","Gene description":"Tumor suppressor candidate 3","Uniprot":["Q13454"],"Chromosome":"8","Position":"15417215-15766649","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"475.5","Extravillous trophoblasts":"344.8","Syncytiotrophoblasts":"900.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Liver - Hepatic stellate cells","Skeletal muscle - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049851","HPA049974"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049851":"AB_2680913","HPA049974":"AB_2680976"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.86e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"}},{"Gene":"TVP23A","Gene synonym":["FAM18A","YDR084C"],"Ensembl":"ENSG00000166676","Gene description":"Trans-golgi network vesicle protein 23 homolog A","Uniprot":["A6NH52"],"Chromosome":"16","Position":"10760919-10818794","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"28.6","Granulosa cells":"87.8","Inhibitory neurons":"27.8","Langerhans cells":"62.2","Oligodendrocyte precursor cells":"22.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060582"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA060582":"AB_2684326"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-4"}},{"Gene":"TVP23B","Gene synonym":["CGI-148","FAM18B","FAM18B1","YDR084C"],"Ensembl":"ENSG00000171928","Gene description":"Trans-golgi network vesicle protein 23 homolog B","Uniprot":["Q9NYZ1"],"Chromosome":"17","Position":"18781111-18806714","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Squamous epithelial cells":"69.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019585","HPA065603"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA019585":"AB_1848385","HPA065603":"AB_2685517"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"}},{"Gene":"TVP23C","Gene synonym":["FAM18B2","MGC8763"],"Ensembl":"ENSG00000175106","Gene description":"Trans-golgi network vesicle protein 23 homolog C","Uniprot":["Q96ET8"],"Chromosome":"17","Position":"15502264-15563595","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"20.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019585","HPA065603"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA019585":"AB_1848385","HPA065603":"AB_2685517"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.39e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"}},{"Gene":"TVP23C-CDRT4","Gene synonym":["FAM18B2-CDRT4"],"Ensembl":"ENSG00000259024","Gene description":"TVP23C-CDRT4 readthrough","Uniprot":[],"Chromosome":"17","Position":"15436021-15563561","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Astrocytes":"15.5","Excitatory neurons":"17.7","Inhibitory neurons":"23.3","Microglial cells":"21.0","Oligodendrocyte precursor cells":"27.9","Oligodendrocytes":"27.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"35.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065603"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA065603":"AB_2685517"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"}},{"Gene":"TXNDC11","Gene synonym":["EFP1"],"Ensembl":"ENSG00000153066","Gene description":"Thioredoxin domain containing 11","Uniprot":["Q6PKC3"],"Chromosome":"16","Position":"11679083-11742857","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Plasma cells":"303.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"115.8","Myeloma":"173.3"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041174","HPA041390"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041174":"AB_10794191","HPA041390":"AB_10796670"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.12e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"}},{"Gene":"TXNDC15","Gene synonym":["2310047H23Rik","C5orf14","FLJ22625"],"Ensembl":"ENSG00000113621","Gene description":"Thioredoxin domain containing 15","Uniprot":["Q96J42"],"Chromosome":"5","Position":"134874371-134901635","Protein class":["Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cilium biogenesis\/degradation"],"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Meckel syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Plasma cells":"224.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015483"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"49000000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA015483":"AB_1845722"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"}},{"Gene":"TXNDC16","Gene synonym":["KIAA1344"],"Ensembl":"ENSG00000087301","Gene description":"Thioredoxin domain containing 16","Uniprot":["Q9P2K2"],"Chromosome":"14","Position":"52430596-52552522","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"26.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"124.5","Inhibitory neurons":"86.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"18.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002543"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA002543":"AB_1079199"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.79e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"}},{"Gene":"TXNDC8","Gene synonym":["bA427L11.2","SPTRX-3","TRX6"],"Ensembl":"ENSG00000204193","Gene description":"Thioredoxin domain containing 8","Uniprot":["Q6A555"],"Chromosome":"9","Position":"110303476-110337884","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"101","RNA tissue specific nTPM":{"testis":"21.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"231","RNA single cell type specific nTPM":{"Early spermatids":"284.7","Late spermatids":"591.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TYMP","Gene synonym":["ECGF1","MNGIE"],"Ensembl":"ENSG00000025708","Gene description":"Thymidine phosphorylase","Uniprot":["P19971"],"Chromosome":"22","Position":"50525752-50530032","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Angiogenesis","Chemotaxis","Differentiation"],"Molecular function":["Developmental protein","Glycosyltransferase","Growth factor","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Neuropathy","Primary mitochondrial disease","Progressive external ophthalmoplegia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"676.8","Langerhans cells":"459.1","Macrophages":"533.9","monocytes":"947.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"135.8","eosinophil":"74.9","intermediate monocyte":"98.4","myeloid DC":"39.5","neutrophil":"114.1","non-classical monocyte":"77.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"39.5","granulocytes":"114.1","monocytes":"135.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"106.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000530","HPA001072","CAB002518"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"11000000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 23: Langerhans cells - Immune response","Subcellular main location":["Nuclear bodies","Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB002518":"AB_563953","HPA000530":"AB_2666017","HPA001072":"AB_1080274"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.34e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.50e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"}},{"Gene":"TYR","Gene synonym":["OCA1","OCA1A","OCAIA"],"Ensembl":"ENSG00000077498","Gene description":"Tyrosinase","Uniprot":["P14679"],"Chromosome":"11","Position":"89177875-89295759","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Melanin biosynthesis"],"Molecular function":["Monooxygenase","Oxidoreductase","Tumor antigen"],"Disease involvement":["Albinism","Deafness","Disease variant","FDA approved drug targets","Waardenburg syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"37","RNA tissue specific nTPM":{"skin 1":"31.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Melanocytes":"299.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"1755","RNA cancer specific FPKM":{"melanoma":"351.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"123","RNA cell line specific nTPM":{"skin cancer":"271.4"},"RNA tissue cell type enrichment":["Skin - Melanocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000079","HPA043241","HPA050889","HPA064583"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB000079":"AB_564045","HPA043241":"AB_2678383","HPA050889":"AB_2681264","HPA064583":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-3"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"TYRO3","Gene synonym":["Brt","Dtk","Etk-2","Rek","RSE","Sky","Tif"],"Ensembl":"ENSG00000092445","Gene description":"TYRO3 protein tyrosine kinase","Uniprot":["Q06418"],"Chromosome":"15","Position":"41557675-41583589","Protein class":["Cancer-related genes","Enzymes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"32.0","ovary":"49.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"41.8","Leydig cells":"45.1","Oligodendrocyte precursor cells":"27.9","Oligodendrocytes":"44.2","Peritubular cells":"45.9","Sertoli cells":"30.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Colon - Enteric glia cells","Kidney - Podocytes","Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071245"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA071245":"AB_2686371"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"}},{"Gene":"TYROBP","Gene synonym":["DAP12","KARAP","PLO-SL","PLOSL"],"Ensembl":"ENSG00000011600","Gene description":"Transmembrane immune signaling adaptor TYROBP","Uniprot":["O43914"],"Chromosome":"19","Position":"35904401-35908295","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"596.8","lymphoid tissue":"423.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"5212.6","Kupffer cells":"2893.4","Langerhans cells":"2460.5","Macrophages":"2602.8","monocytes":"3238.5","NK-cells":"1335.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"6415.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"53","RNA cell line specific nTPM":{"Leukemia":"105.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Stomach - Macrophages","Testis - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009493","HPA041899"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB009493":"AB_638987","HPA041899":"AB_10795266"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"}},{"Gene":"TYRP1","Gene synonym":["b-PROTEIN","CAS2","CATB","GP75","OCA3","TRP","TYRP"],"Ensembl":"ENSG00000107165","Gene description":"Tyrosinase related protein 1","Uniprot":["P17643"],"Chromosome":"9","Position":"12685439-12710285","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Melanin biosynthesis"],"Molecular function":["Monooxygenase","Oxidoreductase"],"Disease involvement":["Albinism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"choroid plexus":"44.8","heart muscle":"59.9","skin 1":"145.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"34","RNA single cell type specific nTPM":{"Melanocytes":"3671.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"262","RNA cancer specific FPKM":{"melanoma":"313.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"skin cancer":"388.5"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes","Skin - Melanocytes"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"olfactory bulb":"4.6","thalamus":"1.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000937","CAB002520"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"51000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 16: Skin cancer - Melanocyte processes","Single cell expression cluster":"Cluster 25: Schwann cells & Melanocytes - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB002520":"AB_564153","HPA000937":"AB_1080437"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"}},{"Gene":"TYSND1","Gene synonym":["MGC34695","NET41"],"Ensembl":"ENSG00000156521","Gene description":"Trypsin like peroxisomal matrix peptidase 1","Uniprot":["Q2T9J0"],"Chromosome":"10","Position":"70137981-70146700","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Early spermatids":"121.1","Late spermatids":"227.2","Spermatocytes":"102.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Skin - Keratinocyte (other)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030304"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: NK-cells - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Centrosome"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA030304":"AB_10670560"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"}},{"Gene":"TYW1","Gene synonym":["FLJ10900","MGC23001","MGC60291","RSAFD1","TYW1A","YPL207W"],"Ensembl":"ENSG00000198874","Gene description":"TRNA-yW synthesizing protein 1 homolog","Uniprot":["Q9NV66"],"Chromosome":"7","Position":"66995173-67239519","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["tRNA processing"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"56.9","Oligodendrocytes":"55.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013568","HPA014118","HPA015535","HPA043136","HPA047029","HPA047052","HPA052097"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli","Nucleoli rim"],"Subcellular additional location":null,"Antibody RRID":{"HPA013568":"AB_2668852","HPA014118":"AB_2668941","HPA015535":"AB_1856487","HPA043136":"AB_2678333","HPA047029":"AB_2679909","HPA047052":"AB_2679918","HPA052097":"AB_2681723"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"}},{"Gene":"TYW1B","Gene synonym":["LINC00069","MGC87315","NCRNA00069","RSAFD2"],"Ensembl":"ENSG00000277149","Gene description":"TRNA-yW synthesizing protein 1 homolog B","Uniprot":["Q6NUM6"],"Chromosome":"7","Position":"72558744-72828200","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["tRNA processing"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"46.7","Inhibitory neurons":"27.1","Oligodendrocyte precursor cells":"22.1","Oligodendrocytes":"39.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013568","HPA014118","HPA043136","HPA047029","HPA047052","HPA052097"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Nucleoli","Nucleoli rim"],"Subcellular additional location":null,"Antibody RRID":{"HPA013568":"AB_2668852","HPA014118":"AB_2668941","HPA043136":"AB_2678333","HPA047029":"AB_2679909","HPA047052":"AB_2679918","HPA052097":"AB_2681723"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"}},{"Gene":"UBA1","Gene synonym":["A1S9T","CFAP124","GXP1","POC20","UBE1","UBE1X"],"Ensembl":"ENSG00000130985","Gene description":"Ubiquitin like modifier activating enzyme 1","Uniprot":["P22314"],"Chromosome":"X","Position":"47190861-47215128","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Ligase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000289","HPA001506","CAB019435","CAB073410"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB019435":"AB_2211440","CAB073410":null,"HPA000289":"AB_1080443","HPA001506":"AB_2756305"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.10e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.78e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"}},{"Gene":"UBA2","Gene synonym":["FLJ13058","HRIHFB2115","SAE2"],"Ensembl":"ENSG00000126261","Gene description":"Ubiquitin like modifier activating enzyme 2","Uniprot":["Q9UBT2"],"Chromosome":"19","Position":"34428352-34471251","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"220.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041436"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA041436":"AB_2677479"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.76e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.02e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"}},{"Gene":"UBA52","Gene synonym":["CEP52","HUBCEP52","L40","MGC126879","MGC126881","MGC57125","RPL40"],"Ensembl":"ENSG00000221983","Gene description":"Ubiquitin A-52 residue ribosomal protein fusion product 1","Uniprot":["P62987"],"Chromosome":"19","Position":"18571730-18577550","Protein class":["Predicted intracellular proteins","Ribosomal proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"11966.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041344","HPA049132","HPA056624"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 39: Non-specific - Translation","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA041344":"AB_2677422","HPA049132":"AB_2680646","HPA056624":"AB_2683196"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"}},{"Gene":"UBA6","Gene synonym":["FLJ10808","UBE1L2"],"Ensembl":"ENSG00000033178","Gene description":"Ubiquitin like modifier activating enzyme 6","Uniprot":["A0AVT1"],"Chromosome":"4","Position":"67612652-67701155","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037001"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA037001":"AB_10672787"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.01e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"}},{"Gene":"UBA7","Gene synonym":["D8","UBA1B","UBE1L","UBE2"],"Ensembl":"ENSG00000182179","Gene description":"Ubiquitin like modifier activating enzyme 7","Uniprot":["P41226"],"Chromosome":"3","Position":"49805209-49813953","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"51.3","Proximal enterocytes":"46.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"30.0"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015444","HPA058182"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB015444":"AB_793598","HPA058182":"AB_2683631"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.48e-4"}},{"Gene":"UBAC2","Gene synonym":["FLJ30548","PHGDHL1","RP11-178C10.1"],"Ensembl":"ENSG00000134882","Gene description":"UBA domain containing 2","Uniprot":["Q8NBM4"],"Chromosome":"13","Position":"99200774-99386504","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013448"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA013448":"AB_1855301"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"}},{"Gene":"UBE2E2","Gene synonym":["FLJ25157","UbcH8"],"Ensembl":"ENSG00000182247","Gene description":"Ubiquitin conjugating enzyme E2 E2","Uniprot":["Q96LR5"],"Chromosome":"3","Position":"23203020-23591794","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"643.3","Inhibitory neurons":"390.7","Microglial cells":"392.2","Oligodendrocyte precursor cells":"491.5","Oligodendrocytes":"797.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"41.7","intermediate monocyte":"50.3","memory B-cell":"35.1","myeloid DC":"57.6","naive B-cell":"40.1","non-classical monocyte":"54.4","plasmacytoid DC":"74.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"40.1","dendritic cells":"74.0","monocytes":"54.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003303","HPA028872","HPA030445","CAB073417"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB073417":null,"HPA003303":"AB_1858521","HPA028872":"AB_10966277","HPA030445":"AB_10669599"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-3"}},{"Gene":"UBE2J1","Gene synonym":["CGI-76","HSPC153","NCUBE1","UBC6"],"Ensembl":"ENSG00000198833","Gene description":"Ubiquitin conjugating enzyme E2 J1","Uniprot":["Q9Y385"],"Chromosome":"6","Position":"89326625-89352722","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"1521.3","Plasma cells":"975.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"219.0"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003509","CAB073419"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB073419":null,"HPA003509":"AB_1858531"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.87e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.90e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.43e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"}},{"Gene":"UBE2J2","Gene synonym":["NCUBE2","Ubc6p"],"Ensembl":"ENSG00000160087","Gene description":"Ubiquitin conjugating enzyme E2 J2","Uniprot":["Q8N2K1"],"Chromosome":"1","Position":"1253909-1273864","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway","Unfolded protein response"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"274.3","Late spermatids":"436.4","Spermatocytes":"246.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.00e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"}},{"Gene":"UBE2S","Gene synonym":["E2-EPF"],"Ensembl":"ENSG00000108106","Gene description":"Ubiquitin conjugating enzyme E2 S","Uniprot":["Q16763"],"Chromosome":"19","Position":"55399745-55407788","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"115.9","testis":"158.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"341.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015228","HPA057150"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB015228":null,"HPA057150":"AB_2683351"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.05e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.00e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.16e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"}},{"Gene":"UBE3B","Gene synonym":[],"Ensembl":"ENSG00000151148","Gene description":"Ubiquitin protein ligase E3B","Uniprot":["Q7Z3V4"],"Chromosome":"12","Position":"109477402-109536705","Protein class":["Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041012"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA041012":"AB_10964435"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"}},{"Gene":"UBIAD1","Gene synonym":["SCCD","TERE1"],"Ensembl":"ENSG00000120942","Gene description":"UbiA prenyltransferase domain containing 1","Uniprot":["Q9Y5Z9"],"Chromosome":"1","Position":"11273198-11296049","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Menaquinone biosynthesis","Ubiquinone biosynthesis"],"Molecular function":["Prenyltransferase","Transferase"],"Disease involvement":["Corneal dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Sebaceous gland cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044862"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA044862":"AB_2679117"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.80e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"UBR2","Gene synonym":["bA49A4.1","C6orf133","dJ392M17.3","KIAA0349"],"Ensembl":"ENSG00000024048","Gene description":"Ubiquitin protein ligase E3 component n-recognin 2","Uniprot":["Q8IWV8"],"Chromosome":"6","Position":"42564029-42693505","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"136.5","Inhibitory neurons":"139.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"38.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027869","HPA027880"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA027869":"AB_10600416","HPA027880":"AB_10601217"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.65e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-3"}},{"Gene":"UBR3","Gene synonym":["DKFZp434P117","FLJ37422","KIAA2024","ZNF650"],"Ensembl":"ENSG00000144357","Gene description":"Ubiquitin protein ligase E3 component n-recognin 3","Uniprot":["Q6ZT12"],"Chromosome":"2","Position":"169827454-170084131","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"71.2","tongue":"87.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"157.5","Excitatory neurons":"300.8","Inhibitory neurons":"295.1","Oligodendrocyte precursor cells":"222.4","Oligodendrocytes":"271.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035390"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA035390":"AB_10670699"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"}},{"Gene":"UBR4","Gene synonym":["KIAA0462","KIAA1307","RBAF600","ZUBR1"],"Ensembl":"ENSG00000127481","Gene description":"Ubiquitin protein ligase E3 component n-recognin 4","Uniprot":["Q5T4S7"],"Chromosome":"1","Position":"19074510-19210266","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Calmodulin-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"39.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013394","HPA021046"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"HPA013394":null,"HPA021046":"AB_1858578"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"}},{"Gene":"UBXN8","Gene synonym":["D8S2298E","REP8","UBXD6"],"Ensembl":"ENSG00000104691","Gene description":"UBX domain protein 8","Uniprot":["O00124"],"Chromosome":"8","Position":"30729131-30767006","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"79.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"127.1","Granulosa cells":"203.8","Late spermatids":"212.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017725","HPA077538"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoplasm","Nucleoli"],"Antibody RRID":{"HPA017725":"AB_1847462","HPA077538":"AB_2686844"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.13e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.25e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"}},{"Gene":"UCHL5","Gene synonym":["CGI-70","INO80R","UCH37"],"Ensembl":"ENSG00000116750","Gene description":"Ubiquitin C-terminal hydrolase L5","Uniprot":["Q9Y5K5"],"Chromosome":"1","Position":"193012250-193060080","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA recombination","DNA repair","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"140.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005908","HPA006069"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA005908":"AB_1858585","HPA006069":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.10e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"}},{"Gene":"UGCG","Gene synonym":["GCS"],"Ensembl":"ENSG00000148154","Gene description":"UDP-glucose ceramide glucosyltransferase","Uniprot":["Q16739"],"Chromosome":"9","Position":"111896814-111935369","Protein class":["Enzymes","FDA approved drug targets","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"112.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"459.9","Glandular and luminal cells":"295.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"21","RNA blood cell specific nTPM":{"plasmacytoid DC":"109.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"dendritic cells":"109.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Neutrophils"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024124"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024124":"AB_1858595"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.62e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.44e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"}},{"Gene":"UGGT1","Gene synonym":["HUGT1","UGCGL1"],"Ensembl":"ENSG00000136731","Gene description":"UDP-glucose glycoprotein glucosyltransferase 1","Uniprot":["Q9NYU2"],"Chromosome":"2","Position":"128091200-128195677","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012761","HPA015127"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4000000","Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA012761":"AB_1858597","HPA015127":"AB_1858596"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.37e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"}},{"Gene":"UGT1A1","Gene synonym":["GNT1","UGT1","UGT1A"],"Ensembl":"ENSG00000241635","Gene description":"UDP glucuronosyltransferase family 1 member A1","Uniprot":["P22309"],"Chromosome":"2","Position":"233760270-233773300","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"26","RNA tissue specific nTPM":{"intestine":"201.2","liver":"322.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hepatocytes":"94.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"19","RNA cancer specific FPKM":{"liver cancer":"16.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"48.8"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Liver - Hepatocytes","Lung - Respiratory ciliated cells","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-4"}},{"Gene":"UGT1A10","Gene synonym":["UGT1J"],"Ensembl":"ENSG00000242515","Gene description":"UDP glucuronosyltransferase family 1 member A10","Uniprot":["Q9HAW8"],"Chromosome":"2","Position":"233636454-233773305","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"22.0","intestine":"79.5","stomach 1":"32.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"1.8","Distal enterocytes":"1.6","Gastric mucus-secreting cells":"4.8","Intestinal goblet cells":"1.2","Paneth cells":"1.4","Proximal enterocytes":"3.4","Squamous epithelial cells":"4.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"9.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bile duct cancer":"79.6","Gallbladder cancer":"128.2","pancreatic cancer":"73.4"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.55e-4"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-3"}},{"Gene":"UGT1A3","Gene synonym":["UGT1C"],"Ensembl":"ENSG00000243135","Gene description":"UDP glucuronosyltransferase family 1 member A3","Uniprot":["P35503"],"Chromosome":"2","Position":"233729108-233773299","Protein class":["Cancer-related genes","Enzymes","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"liver":"73.5"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"liver cancer":"2.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Esophageal cancer":"2.4","Gallbladder cancer":"3.3"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"}},{"Gene":"UGT1A4","Gene synonym":["HUG-BR2","UGT1D"],"Ensembl":"ENSG00000244474","Gene description":"UDP glucuronosyltransferase family 1 member A4","Uniprot":["P22310"],"Chromosome":"2","Position":"233718736-233773300","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"68","RNA tissue specific nTPM":{"liver":"391.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Hepatocytes":"17.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"487","RNA cancer specific FPKM":{"liver cancer":"24.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"}},{"Gene":"UGT1A5","Gene synonym":["UGT1E"],"Ensembl":"ENSG00000240224","Gene description":"UDP glucuronosyltransferase family 1 member A5","Uniprot":["P35504"],"Chromosome":"2","Position":"233712992-233773299","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"2.4","intestine":"7.4","liver":"1.7"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"UGT1A6","Gene synonym":["GNT1","HLUGP","UGT1F"],"Ensembl":"ENSG00000167165","Gene description":"UDP glucuronosyltransferase family 1 member A6","Uniprot":["P19224"],"Chromosome":"2","Position":"233691607-233773300","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"kidney":"71.3","liver":"143.3","urinary bladder":"88.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"18.6","Early spermatids":"25.0","Gastric mucus-secreting cells":"14.3","Late spermatids":"35.9","Squamous epithelial cells":"16.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"7.2","lung cancer":"3.1","renal cancer":"7.6","urothelial cancer":"3.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"254.4"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Lung - Respiratory ciliated cells","Skin - Keratinocyte (other)","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009819","HPA054065","HPA056023"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Endoplasmic reticulum"],"Antibody RRID":{"CAB009819":"AB_2241481","HPA054065":"AB_2682367","HPA056023":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.89e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.18e-2"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"}},{"Gene":"UGT1A7","Gene synonym":["UGT1G"],"Ensembl":"ENSG00000244122","Gene description":"UDP glucuronosyltransferase family 1 member A7","Uniprot":["Q9HAW7"],"Chromosome":"2","Position":"233681938-233773299","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"esophagus":"83.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"11.2","Squamous epithelial cells":"44.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"cervical cancer":"1.2","head and neck cancer":"2.3","lung cancer":"3.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"cervical cancer":"37.5"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Lung - Respiratory ciliated cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"}},{"Gene":"UGT1A8","Gene synonym":["UGT1H"],"Ensembl":"ENSG00000242366","Gene description":"UDP glucuronosyltransferase family 1 member A8","Uniprot":["Q9HAW9"],"Chromosome":"2","Position":"233617645-233773310","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"15.9","liver":"20.1","urinary bladder":"30.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"1.1","Paneth cells":"1.5","Proximal enterocytes":"1.0","Squamous epithelial cells":"1.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"urothelial cancer":"2.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bile duct cancer":"8.7","Bladder cancer":"19.5","colorectal cancer":"7.6"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"}},{"Gene":"UGT1A9","Gene synonym":["HLUGP4","LUGP4","UGT1AI"],"Ensembl":"ENSG00000241119","Gene description":"UDP glucuronosyltransferase family 1 member A9","Uniprot":["O60656"],"Chromosome":"2","Position":"233671898-233773300","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"370","RNA tissue specific nTPM":{"kidney":"458.6","liver":"195.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"Hepatocytes":"7.2","Proximal tubular cells":"5.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"157","RNA cancer specific FPKM":{"liver cancer":"16.1","renal cancer":"16.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Kidney cancer":"101.4"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.04e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"}},{"Gene":"UGT2A1","Gene synonym":[],"Ensembl":"ENSG00000173610","Gene description":"UDP glucuronosyltransferase family 2 member A1 complex locus","Uniprot":["P0DTE4"],"Chromosome":"4","Position":"69588417-69653249","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Olfaction","Sensory transduction"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"choroid plexus":"3.6","kidney":"2.3","liver":"3.6","pituitary gland":"5.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"1.1","Collecting duct cells":"2.0","Proximal tubular cells":"5.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"0.7","lung cancer":"0.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"lung cancer":"1.2","Myeloma":"1.4"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Skin - Sebaceous gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017261","HPA045108"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017261":"AB_10963582","HPA045108":"AB_2679218"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"UGT2A2","Gene synonym":[],"Ensembl":"ENSG00000271271","Gene description":"UDP glucuronosyltransferase family 2 member A2","Uniprot":["P0DTE4","P0DTE5"],"Chromosome":"4","Position":"69588417-69639642","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Olfaction","Sensory transduction"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"kidney":"6.3","liver":"10.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045108"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045108":"AB_2679218"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"UGT2A3","Gene synonym":["FLJ21934"],"Ensembl":"ENSG00000135220","Gene description":"UDP glucuronosyltransferase family 2 member A3","Uniprot":["Q6UWM9"],"Chromosome":"4","Position":"68928463-68951804","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"31.4","kidney":"21.0","liver":"13.3","pancreas":"16.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"90.5","Distal enterocytes":"98.9","Enteroendocrine cells":"46.1","Hepatocytes":"51.7","Paneth cells":"58.7","Proximal enterocytes":"233.0","Proximal tubular cells":"114.4","Undifferentiated cells":"82.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"renal cancer":"46.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045108"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045108":"AB_2679218"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.31e-4"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.07e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"UGT2B10","Gene synonym":[],"Ensembl":"ENSG00000109181","Gene description":"UDP glucuronosyltransferase family 2 member B10","Uniprot":["P36537"],"Chromosome":"4","Position":"68815994-68832023","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"149","RNA tissue specific nTPM":{"liver":"233.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Hepatocytes":"274.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"296","RNA cancer specific FPKM":{"liver cancer":"93.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"liver cancer":"2.3"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045108"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 35: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045108":"AB_2679218"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"UGT2B11","Gene synonym":[],"Ensembl":"ENSG00000213759","Gene description":"UDP glucuronosyltransferase family 2 member B11","Uniprot":["O75310"],"Chromosome":"4","Position":"69199951-69214748","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"21","RNA tissue specific nTPM":{"breast":"239.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Breast glandular cells":"7.8","Cholangiocytes":"7.7","Melanocytes":"5.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"breast cancer":"17.4","liver cancer":"13.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"42","RNA blood cell specific nTPM":{"basophil":"4.7","eosinophil":"3.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"47","RNA blood lineage specific nTPM":{"granulocytes":"4.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"liver cancer":"5.9","prostate cancer":"12.4"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045108"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 5: Breast - Unknown function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045108":"AB_2679218"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"}},{"Gene":"UGT2B15","Gene synonym":["UGT2B8"],"Ensembl":"ENSG00000196620","Gene description":"UDP glucuronosyltransferase family 2 member B15","Uniprot":["P54855"],"Chromosome":"4","Position":"68646597-68670652","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Steroid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"gallbladder":"77.7","liver":"291.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Cholangiocytes":"215.6","Hepatocytes":"140.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"liver cancer":"120.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"prostate cancer":"4.6"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045108"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045108":"AB_2679218"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.82e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.50e-4"}},{"Gene":"UGT2B17","Gene synonym":[],"Ensembl":"ENSG00000197888","Gene description":"UDP glucuronosyltransferase family 2 member B17","Uniprot":["O75795"],"Chromosome":"4","Position":"68537184-68568527","Protein class":["Enzymes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Steroid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"intestine":"460.0","liver":"136.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal enterocytes":"169.1","Enteroendocrine cells":"125.0","Undifferentiated cells":"53.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"colorectal cancer":"16.3","liver cancer":"10.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"40","RNA blood cell specific nTPM":{"memory B-cell":"2.8","naive B-cell":"8.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"61","RNA blood lineage specific nTPM":{"B-cells":"8.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"1.7","Myeloma":"4.1","prostate cancer":"2.1"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045108"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 50: L-1236 & L-428 - Unknown function","Single cell expression cluster":"Cluster 50: Enterocytes - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045108":"AB_2679218"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"}},{"Gene":"UGT2B28","Gene synonym":[],"Ensembl":"ENSG00000135226","Gene description":"UDP glucuronosyltransferase family 2 member B28","Uniprot":["Q9BY64"],"Chromosome":"4","Position":"69280475-69295050","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"breast":"198.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"32","RNA single cell type specific nTPM":{"Cholangiocytes":"11.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"breast cancer":"1.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"1.3"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"prostate cancer":"3.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045108"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 5: Breast - Unknown function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045108":"AB_2679218"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-5"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-4"}},{"Gene":"UGT2B4","Gene synonym":["UGT2B11"],"Ensembl":"ENSG00000156096","Gene description":"UDP glucuronosyltransferase family 2 member B4","Uniprot":["P06133"],"Chromosome":"4","Position":"69480165-69526014","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"107","RNA tissue specific nTPM":{"liver":"1273.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"15","RNA single cell type specific nTPM":{"Hepatocytes":"816.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"96","RNA cancer specific FPKM":{"liver cancer":"351.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"18","RNA cell line specific nTPM":{"liver cancer":"31.5"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033260","HPA045108"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033260":"AB_2241496","HPA045108":"AB_2679218"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"UGT2B7","Gene synonym":["UGT2B9"],"Ensembl":"ENSG00000171234","Gene description":"UDP glucuronosyltransferase family 2 member B7","Uniprot":["P16662"],"Chromosome":"4","Position":"69051363-69112987","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Steroid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"21","RNA tissue specific nTPM":{"kidney":"1299.8","liver":"1612.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"124.1","Endometrial ciliated cells":"128.4","Glandular and luminal cells":"230.1","Hepatocytes":"515.3","Proximal tubular cells":"965.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"liver cancer":"116.4","renal cancer":"101.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"88.8","Uterine cancer":"39.5"},"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Liver - Hepatocytes","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045108"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045108":"AB_2679218"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.65e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.79e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.38e-4"}},{"Gene":"UGT3A1","Gene synonym":["FLJ34658"],"Ensembl":"ENSG00000145626","Gene description":"UDP glycosyltransferase family 3 member A1","Uniprot":["Q6NUS8"],"Chromosome":"5","Position":"35951006-36001028","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"kidney":"51.1","liver":"58.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"29.5","Early spermatids":"153.6","Hepatocytes":"64.7","Late spermatids":"24.8","Proximal tubular cells":"70.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"15","RNA cancer specific FPKM":{"liver cancer":"6.7","renal cancer":"4.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Kidney cancer":"2.7","Sarcoma":"2.1"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047697","HPA056290"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 42: Sarcoma - Muscle contraction","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA047697":"AB_2680122","HPA056290":"AB_2683088"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-1"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"UGT3A2","Gene synonym":[],"Ensembl":"ENSG00000168671","Gene description":"UDP glycosyltransferase family 3 member A2","Uniprot":["Q3SY77"],"Chromosome":"5","Position":"36035021-36071358","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"6.5","lymphoid tissue":"14.7","skin 1":"10.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"2.0","Early spermatids":"4.0","Late spermatids":"8.8","Proximal tubular cells":"2.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"testis cancer":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Bone cancer":"190.4"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059475"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA059475":"AB_2684031"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-3"}},{"Gene":"UGT8","Gene synonym":["CGT"],"Ensembl":"ENSG00000174607","Gene description":"UDP glycosyltransferase 8","Uniprot":["Q16880"],"Chromosome":"4","Position":"114598770-114678225","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"brain":"266.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Oligodendrocytes":"775.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"memory B-cell":"6.9","naive B-cell":"10.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"B-cells":"10.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Skin - Eccrine sweat gland cells","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014405","HPA065785"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA014405":"AB_1858606","HPA065785":"AB_2685559"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"}},{"Gene":"ULBP1","Gene synonym":["RAET1I"],"Ensembl":"ENSG00000111981","Gene description":"UL16 binding protein 1","Uniprot":["Q9BZM6"],"Chromosome":"6","Position":"149963943-149973715","Protein class":["Predicted membrane proteins"],"Biological process":["Host-virus interaction","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"4.4","lung":"1.7","testis":"3.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast myoepithelial cells":"3.9","Sertoli cells":"2.8","Squamous epithelial cells":"2.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"4.4","cerebral cortex":"1.9","hippocampal formation":"1.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007547","HPA071005"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA007547":"AB_1079430","HPA071005":"AB_2686332"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"}},{"Gene":"ULBP2","Gene synonym":["RAET1H"],"Ensembl":"ENSG00000131015","Gene description":"UL16 binding protein 2","Uniprot":["Q9BZM5"],"Chromosome":"6","Position":"149942014-149949235","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Host-virus interaction","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"6.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"25.8","Basal respiratory cells":"16.6","Exocrine glandular cells":"10.2","Late spermatids":"11.0","Squamous epithelial cells":"12.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"12.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"2.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"T-cells":"2.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018974","HPA066741"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB018974":null,"HPA066741":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.07e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.44e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-1"}},{"Gene":"ULBP3","Gene synonym":["RAET1N"],"Ensembl":"ENSG00000131019","Gene description":"UL16 binding protein 3","Uniprot":["Q9BZM4"],"Chromosome":"6","Position":"150061053-150069121","Protein class":["Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"6.5","testis":"6.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"7.7","Alveolar cells type 1":"5.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056541","HPA063007"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Centriolar satellite"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA056541":null,"HPA063007":"AB_2684920"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"}},{"Gene":"ULK4","Gene synonym":["FAM7C1","FLJ20574","REC01035"],"Ensembl":"ENSG00000168038","Gene description":"Unc-51 like kinase 4","Uniprot":["Q96C45"],"Chromosome":"3","Position":"41246599-41962130","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"23.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"339.1","Excitatory neurons":"106.9","Inhibitory neurons":"96.7","Late spermatids":"432.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Fibroblast_1","Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017930"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 52: Endometrial stromal cells - ECM organization","Subcellular main location":["Nucleoplasm","Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA017930":"AB_1858615"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"}},{"Gene":"UMAD1","Gene synonym":["RPA3-AS1","RPA3OS"],"Ensembl":"ENSG00000219545","Gene description":"UBAP1-MVB12-associated (UMA) domain containing 1","Uniprot":["C9J7I0"],"Chromosome":"7","Position":"7640711-7968020","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"95.3","Inhibitory neurons":"111.7","Microglial cells":"77.5","Oligodendrocyte precursor cells":"77.5","Oligodendrocytes":"112.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044806"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA044806":"AB_10961141"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.73e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"}},{"Gene":"UMOD","Gene synonym":[],"Ensembl":"ENSG00000169344","Gene description":"Uromodulin","Uniprot":["P07911"],"Chromosome":"16","Position":"20333051-20356301","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Ciliopathy","Disease variant","Nephronophthisis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"693","RNA tissue specific nTPM":{"kidney":"2277.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"164","RNA single cell type specific nTPM":{"Collecting duct cells":"206.8","Distal tubular cells":"410.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"39","RNA cancer specific FPKM":{"renal cancer":"5.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Kidney - Ascending Loop of Henle cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009446","HPA043420","HPA054721"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":55000000,"Blood concentration - Conc. blood MS [pg\/L]":"66000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009446":"AB_2212378","HPA043420":"AB_2678474","HPA054721":"AB_2682585"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"UMODL1","Gene synonym":[],"Ensembl":"ENSG00000177398","Gene description":"Uromodulin like 1","Uniprot":["Q5DID0"],"Chromosome":"21","Position":"42062959-42143453","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.8","fallopian tube":"1.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"3.9","Endometrial ciliated cells":"4.1","Intestinal goblet cells":"1.1","Late spermatids":"2.4","Spermatocytes":"1.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"testis cancer":"2.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"1.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067245"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA067245":"AB_2685810"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-7"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"}},{"Gene":"UNC13D","Gene synonym":["Munc13-4"],"Ensembl":"ENSG00000092929","Gene description":"Unc-13 homolog D","Uniprot":["Q70J99"],"Chromosome":"17","Position":"75827225-75844552","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Exocytosis"],"Molecular function":null,"Disease involvement":["Familial hemophagocytic lymphohistiocytosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"58.9","lymphoid tissue":"66.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"132.5","Hofbauer cells":"56.2","NK-cells":"45.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"cerebellum":"5.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067117","HPA073525"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA067117":"AB_2685784","HPA073525":"AB_2686615"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.01e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.28e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"}},{"Gene":"UNC45A","Gene synonym":["GC-UNC45","SMAP-1"],"Ensembl":"ENSG00000140553","Gene description":"Unc-45 myosin chaperone A","Uniprot":["Q9H3U1"],"Chromosome":"15","Position":"90930180-90954093","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Myogenesis"],"Molecular function":["Chaperone","Developmental protein"],"Disease involvement":["Deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039228"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA039228":"AB_2676402"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.72e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.46e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"}},{"Gene":"UNC50","Gene synonym":["GMH1","UNCL","URP"],"Ensembl":"ENSG00000115446","Gene description":"Unc-50 inner nuclear membrane RNA binding protein","Uniprot":["Q53HI1"],"Chromosome":"2","Position":"98608579-98618515","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"207.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027009"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027009":"AB_1858620"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.79e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.89e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-3"}},{"Gene":"UNC5A","Gene synonym":["KIAA1976","UNC5H1"],"Ensembl":"ENSG00000113763","Gene description":"Unc-5 netrin receptor A","Uniprot":["Q6ZN44"],"Chromosome":"5","Position":"176810519-176880898","Protein class":["Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"30.4","pituitary gland":"14.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"53.6","Horizontal cells":"19.9","Inhibitory neurons":"18.9","Muller glia cells":"10.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"7.5"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"amygdala":"10.5","basal ganglia":"15.1","cerebral cortex":"30.4","hippocampal formation":"16.3","white matter":"11.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"18.7"},"RNA tissue cell type enrichment":["Stomach - Parietal cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071450"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA071450":"AB_2686397"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.23e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.17e-2"}},{"Gene":"UNC5B","Gene synonym":["p53RDL1","UNC5H2"],"Ensembl":"ENSG00000107731","Gene description":"Unc-5 netrin receptor B","Uniprot":["Q8IZJ1"],"Chromosome":"10","Position":"71212570-71302864","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis","Apoptosis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"48.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"77.1","Horizontal cells":"75.6","Muller glia cells":"48.2","Oligodendrocytes":"84.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"76.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076687"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 70: Basal prostatic cells - Lipid metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA076687":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.01e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.80e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.54e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"}},{"Gene":"UNC5C","Gene synonym":[],"Ensembl":"ENSG00000182168","Gene description":"Unc-5 netrin receptor C","Uniprot":["O95185"],"Chromosome":"4","Position":"95162504-95549206","Protein class":["Disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Alzheimer disease","Amyloidosis","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"40.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocytes":"1962.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"thyroid cancer":"6.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Neuroblastoma":"53.5"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells","Skin - Eccrine sweat gland cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"310000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-4"}},{"Gene":"UNC5CL","Gene synonym":["MGC34763","ZUD"],"Ensembl":"ENSG00000124602","Gene description":"Unc-5 family C-terminal like","Uniprot":["Q8IV45"],"Chromosome":"6","Position":"41026895-41039221","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"37.1","kidney":"58.6","liver":"52.8","pancreas":"36.2","stomach 1":"23.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"34.6","Ductal cells":"33.0","Exocrine glandular cells":"68.3","Gastric mucus-secreting cells":"38.2","Hepatocytes":"24.6","Proximal enterocytes":"33.0","Proximal tubular cells":"42.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015725"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA015725":"AB_2669283"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.60e-6"}},{"Gene":"UNC5D","Gene synonym":["KIAA1777","Unc5h4"],"Ensembl":"ENSG00000156687","Gene description":"Unc-5 netrin receptor D","Uniprot":["Q6UXZ4"],"Chromosome":"8","Position":"35235475-35796550","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"19.8","intestine":"6.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Excitatory neurons":"630.7","Inhibitory neurons":"752.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"1.4","renal cancer":"1.0"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"hypothalamus":"19.8","thalamus":"7.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"2.8","thyroid cancer":"2.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Beta cells","Prostate - Prostate glandular cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042940"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 32: Neurons - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042940":"AB_10959525"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"UNC79","Gene synonym":["KIAA1409"],"Ensembl":"ENSG00000133958","Gene description":"Unc-79 homolog, NALCN channel complex subunit","Uniprot":["Q9P2D8"],"Chromosome":"14","Position":"93333219-93707876","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"5.1","pituitary gland":"11.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"516.4","Inhibitory neurons":"452.7","Oligodendrocyte precursor cells":"259.0","Oligodendrocytes":"191.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"4.9"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071881"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA071881":"AB_2732189"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"}},{"Gene":"UNC80","Gene synonym":["C2orf21","FLJ33496","KIAA1843","UNC-80"],"Ensembl":"ENSG00000144406","Gene description":"Unc-80 homolog, NALCN channel complex subunit","Uniprot":["Q8N2C7"],"Chromosome":"2","Position":"209771832-209999300","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"21.0","pituitary gland":"13.6","retina":"18.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"98.9","Excitatory neurons":"425.8","Horizontal cells":"80.8","Inhibitory neurons":"346.7","Oligodendrocyte precursor cells":"278.2","Rod photoreceptor cells":"78.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.8","prostate cancer":"0.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"4.2","prostate cancer":"3.3"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Kidney - Intercalated cells","Pancreas - Alpha cells","Pancreas - Beta cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042472","HPA050959"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA042472":"AB_10965318","HPA050959":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-3"}},{"Gene":"UNC93A","Gene synonym":["dJ366N23.1","dJ366N23.2"],"Ensembl":"ENSG00000112494","Gene description":"Unc-93 homolog A","Uniprot":["Q86WB7"],"Chromosome":"6","Position":"167271169-167316014","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"esophagus":"5.1","intestine":"9.6","liver":"14.1","skin 1":"19.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"11.8","Endometrial ciliated cells":"2.1","Hepatocytes":"6.3","Proximal enterocytes":"3.4","Suprabasal keratinocytes":"2.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"4.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"colorectal cancer":"6.4","Gastric cancer":"9.0","liver cancer":"3.7"},"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035729"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA035729":"AB_10696508"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"UNC93B1","Gene synonym":["UNC93"],"Ensembl":"ENSG00000110057","Gene description":"Unc-93 homolog B1, TLR signaling regulator","Uniprot":["Q9H1C4"],"Chromosome":"11","Position":"67991100-68004982","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Antiviral defense","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"76.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"147.2","Hofbauer cells":"98.1","Macrophages":"89.4","monocytes":"103.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"14.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Lung - Macrophages","Skeletal muscle - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038716","HPA038717","HPA042803"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 40: Non-specific - Enzymes","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA038716":"AB_2676169","HPA038717":"AB_10674836","HPA042803":"AB_2678176"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.38e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-3"}},{"Gene":"UPK1A","Gene synonym":["TSPAN21"],"Ensembl":"ENSG00000105668","Gene description":"Uroplakin 1A","Uniprot":["O00322"],"Chromosome":"19","Position":"35666516-35678483","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"43.2","urinary bladder":"205.7","vagina":"52.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Club cells":"69.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"41","RNA cancer specific FPKM":{"urothelial cancer":"148.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bladder cancer":"23.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049879"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049879":"AB_2680929"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"}},{"Gene":"UPK1B","Gene synonym":["TSPAN20","UPK1"],"Ensembl":"ENSG00000114638","Gene description":"Uroplakin 1B","Uniprot":["O75841"],"Chromosome":"3","Position":"119173517-119205143","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"stomach 1":"33.8","urinary bladder":"88.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"32.7","Club cells":"160.0","Glandular and luminal cells":"83.4","Ionocytes":"35.1","Respiratory ciliated cells":"35.2","Thymic epithelial cells":"125.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"urothelial cancer":"147.3"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"basal ganglia":"1.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"246.3"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031799","HPA031800"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA031799":"AB_10671579","HPA031800":"AB_10671580"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.87e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.76e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"}},{"Gene":"UPK2","Gene synonym":["MGC138598","UP2","UPII"],"Ensembl":"ENSG00000110375","Gene description":"Uroplakin 2","Uniprot":["O00526"],"Chromosome":"11","Position":"118925164-118958559","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"28","RNA tissue specific nTPM":{"urinary bladder":"70.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Club cells":"25.0","Cytotrophoblasts":"10.5","Syncytiotrophoblasts":"11.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"72","RNA cancer specific FPKM":{"urothelial cancer":"339.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"36.9"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043312","HPA061106"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043312":"AB_2678420","HPA061106":"AB_2684429"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.57e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.30e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"}},{"Gene":"UPK3A","Gene synonym":["UPK3"],"Ensembl":"ENSG00000100373","Gene description":"Uroplakin 3A","Uniprot":["O75631"],"Chromosome":"22","Position":"45284949-45295874","Protein class":["Disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"prostate":"21.3","skeletal muscle":"35.0","urinary bladder":"48.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Club cells":"38.8","monocytes":"29.9","Prostatic glandular cells":"62.8","Proximal enterocytes":"28.0","Schwann cells":"15.7"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"prostate cancer":"35.3","urothelial cancer":"78.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"86.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"dendritic cells":"86.6","monocytes":"32.0"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"14.7"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018407","HPA018415"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nuclear membrane","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA018407":"AB_1858641","HPA018415":"AB_1858640"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"}},{"Gene":"UPK3B","Gene synonym":["FLJ32198","MGC10902","p35","UPIIIb"],"Ensembl":"ENSG00000243566","Gene description":"Uroplakin 3B","Uniprot":["Q9BT76"],"Chromosome":"7","Position":"76510525-76516522","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"adipose tissue":"120.6","esophagus":"64.8","lung":"50.0","urinary bladder":"42.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Thymic epithelial cells":"1065.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"ovarian cancer":"64.6","urothelial cancer":"78.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ovarian cancer":"59.8"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010506"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010506":"AB_1080479"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"}},{"Gene":"UPK3BL1","Gene synonym":["UPK3BL","UPLP"],"Ensembl":"ENSG00000267368","Gene description":"Uroplakin 3B like 1","Uniprot":["B0FP48"],"Chromosome":"7","Position":"102637025-102642791","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"272.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"5.1","Distal tubular cells":"3.1","Enteroendocrine cells":"4.0","Intestinal goblet cells":"5.3","Paneth cells":"5.6","Undifferentiated cells":"4.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"90.4"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011403"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011403":"AB_2668503"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.39e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"}},{"Gene":"UPK3BL2","Gene synonym":[],"Ensembl":"ENSG00000284981","Gene description":"Uroplakin 3B like 2","Uniprot":["E5RIL1"],"Chromosome":"7","Position":"102538417-102543849","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"67.3","lymphoid tissue":"76.8"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011403"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Plasmacytoid DCs - Unknown function","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 62: B-cells - B-cell activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011403":"AB_2668503"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"UPP1","Gene synonym":["UDRPASE","UP","UPASE","UPP"],"Ensembl":"ENSG00000183696","Gene description":"Uridine phosphorylase 1","Uniprot":["Q16831"],"Chromosome":"7","Position":"48088628-48108736","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"66.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"314.6","monocytes":"244.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"62.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gallbladder cancer":"122.4"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Prostate - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054040","HPA055394"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA054040":"AB_2682352","HPA055394":"AB_2682805"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.97e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"}},{"Gene":"UPP2","Gene synonym":["UDRPASE2","UP2","UPASE2"],"Ensembl":"ENSG00000007001","Gene description":"Uridine phosphorylase 2","Uniprot":["O95045"],"Chromosome":"2","Position":"157876702-158136154","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"kidney":"45.8","liver":"23.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"23.4","Excitatory neurons":"32.0","Inhibitory neurons":"20.3","Oligodendrocyte precursor cells":"26.5","Proximal tubular cells":"70.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"liver cancer":"3.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035225","HPA035226"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Mitochondria"],"Antibody RRID":{"HPA035225":"AB_10604002","HPA035226":"AB_10696503"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"}},{"Gene":"UQCC1","Gene synonym":["BFZB","C20orf44","CBP3","FLJ10850","UQCC"],"Ensembl":"ENSG00000101019","Gene description":"Ubiquinol-cytochrome c reductase complex assembly factor 1","Uniprot":["Q9NVA1"],"Chromosome":"20","Position":"35302566-35412031","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"106.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"63.7","Inhibitory neurons":"67.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034875"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Actin filaments"],"Antibody RRID":{"HPA034875":"AB_10603226"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"}},{"Gene":"UQCC3","Gene synonym":["C11orf83","UNQ655"],"Ensembl":"ENSG00000204922","Gene description":"Ubiquinol-cytochrome c reductase complex assembly factor 3","Uniprot":["Q6UW78"],"Chromosome":"11","Position":"62670273-62673686","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["ATP synthesis"],"Molecular function":null,"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"208.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046851"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA046851":"AB_2679839"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.55e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"UQCR10","Gene synonym":["HSPC051","QCR9","UCCR7.2","UCRC"],"Ensembl":"ENSG00000184076","Gene description":"Ubiquinol-cytochrome c reductase, complex III subunit X","Uniprot":["Q9UDW1"],"Chromosome":"22","Position":"29767369-29770413","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"3962.0","Distal tubular cells":"2630.8","Proximal tubular cells":"2020.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-3"}},{"Gene":"UQCR11","Gene synonym":["QCR10","UQCR"],"Ensembl":"ENSG00000127540","Gene description":"Ubiquinol-cytochrome c reductase, complex III subunit XI","Uniprot":["O14957"],"Chromosome":"19","Position":"1597169-1605473","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":["Electron transport","Respiratory chain","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"297.7","skeletal muscle":"311.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"2358.0","Distal tubular cells":"2612.2","Hepatocytes":"2213.7","Proximal enterocytes":"2160.0","Proximal tubular cells":"2082.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.23e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.86e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.65e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"}},{"Gene":"URB2","Gene synonym":["KIAA0133","NET10","NPA2"],"Ensembl":"ENSG00000135763","Gene description":"URB2 ribosome biogenesis homolog","Uniprot":["Q14146"],"Chromosome":"1","Position":"229626247-229660200","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"19.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008902","HPA046788"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA008902":"AB_2213805","HPA046788":"AB_2679807"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"}},{"Gene":"URGCP","Gene synonym":["DKFZp666G166","DKFZp686O0457","FLJ20654","KIAA1507","URG4"],"Ensembl":"ENSG00000106608","Gene description":"Upregulator of cell proliferation","Uniprot":["Q8TCY9"],"Chromosome":"7","Position":"43875894-43926411","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019879","HPA020134","HPA029468"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019879":"AB_1858651","HPA020134":"AB_1858652","HPA029468":"AB_10601831"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.90e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-3"}},{"Gene":"UROC1","Gene synonym":["FLJ31300","HMFN0320"],"Ensembl":"ENSG00000159650","Gene description":"Urocanate hydratase 1","Uniprot":["Q96N76"],"Chromosome":"3","Position":"126481166-126517773","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Histidine metabolism"],"Molecular function":["Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"336","RNA tissue specific nTPM":{"liver":"116.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatocytes":"53.5","Kupffer cells":"15.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"100","RNA cancer specific FPKM":{"liver cancer":"12.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069863"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"670000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 17: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 29: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA069863":"AB_2732143"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.52e-2"}},{"Gene":"UROD","Gene synonym":[],"Ensembl":"ENSG00000126088","Gene description":"Uroporphyrinogen decarboxylase","Uniprot":["P06132"],"Chromosome":"1","Position":"45010950-45015575","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Heme biosynthesis","Porphyrin biosynthesis"],"Molecular function":["Decarboxylase","Lyase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Erythroid cells":"605.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027468","HPA028668","HPA030350"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2600000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA027468":"AB_1858654","HPA028668":"AB_10603458","HPA030350":"AB_2673440"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"}},{"Gene":"USE1","Gene synonym":["D12","MDS032","p31","SLT1"],"Ensembl":"ENSG00000053501","Gene description":"Unconventional SNARE in the ER 1","Uniprot":["Q9NZ43"],"Chromosome":"19","Position":"17215346-17219829","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026851","HPA047562"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026851":"AB_10602903","HPA047562":"AB_2680089"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"}},{"Gene":"USF2","Gene synonym":["bHLHb12","FIP"],"Ensembl":"ENSG00000105698","Gene description":"Upstream transcription factor 2, c-fos interacting","Uniprot":["Q15853"],"Chromosome":"19","Position":"35268962-35279821","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029764","HPA046567"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA029764":"AB_2673190","HPA046567":"AB_2679702"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.12e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.28e-4"}},{"Gene":"USH2A","Gene synonym":["RP39","USH2"],"Ensembl":"ENSG00000042781","Gene description":"Usherin","Uniprot":["O75445"],"Chromosome":"1","Position":"215622891-216423448","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Hearing","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"22","RNA tissue specific nTPM":{"liver":"7.0","retina":"19.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Cone photoreceptor cells":"100.0","Early spermatids":"53.6","Rod photoreceptor cells":"192.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 7: Neuronal cell lines - Stereocilium","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-4"}},{"Gene":"USP13","Gene synonym":["IsoT-3"],"Ensembl":"ENSG00000058056","Gene description":"Ubiquitin specific peptidase 13","Uniprot":["Q92995"],"Chromosome":"3","Position":"179653032-179804366","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Autophagy","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"149.2","tongue":"108.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"206.7","Inhibitory neurons":"51.0","Skeletal myocytes":"57.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"15.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004827"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA004827":"AB_1080497"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.40e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.46e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.06e-4"}},{"Gene":"USP19","Gene synonym":["KIAA0891","ZMYND9"],"Ensembl":"ENSG00000172046","Gene description":"Ubiquitin specific peptidase 19","Uniprot":["O94966"],"Chromosome":"3","Position":"49108046-49120938","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.05e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"}},{"Gene":"USP20","Gene synonym":["KIAA1003"],"Ensembl":"ENSG00000136878","Gene description":"Ubiquitin specific peptidase 20","Uniprot":["Q9Y2K6"],"Chromosome":"9","Position":"129834698-129881828","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Endocytosis","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006287","HPA007008"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":["Nucleoplasm","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA006287":"AB_1080510","HPA007008":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.01e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.01e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.54e-7"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.65e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"}},{"Gene":"USP24","Gene synonym":["KIAA1057"],"Ensembl":"ENSG00000162402","Gene description":"Ubiquitin specific peptidase 24","Uniprot":["Q9UPU5"],"Chromosome":"1","Position":"55066359-55215364","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"529.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026723","HPA028428","HPA067124"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA026723":"AB_10599851","HPA028428":"AB_10600991","HPA067124":"AB_2685785"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"}},{"Gene":"USP30","Gene synonym":["FLJ40511","MGC10702"],"Ensembl":"ENSG00000135093","Gene description":"Ubiquitin specific peptidase 30","Uniprot":["Q70CQ3"],"Chromosome":"12","Position":"109023089-109088023","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"53.8","Oligodendrocytes":"39.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016952"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016952":"AB_1858680"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.23e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"}},{"Gene":"USP33","Gene synonym":["KIAA1097","VDU1"],"Ensembl":"ENSG00000077254","Gene description":"Ubiquitin specific peptidase 33","Uniprot":["Q8TEY7"],"Chromosome":"1","Position":"77695987-77759852","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Endocytosis","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"155.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005719"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA005719":"AB_10601708"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.19e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"}},{"Gene":"USP45","Gene synonym":["MGC14793"],"Ensembl":"ENSG00000123552","Gene description":"Ubiquitin specific peptidase 45","Uniprot":["Q70EL2"],"Chromosome":"6","Position":"99432325-99521728","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Disease variant","Leber congenital amaurosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"53.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"46.5","Inhibitory neurons":"43.5","Oligodendrocytes":"37.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"53.5"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029602","HPA029604"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA029602":"AB_10600418","HPA029604":"AB_10602283"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"}},{"Gene":"UST","Gene synonym":["2OST"],"Ensembl":"ENSG00000111962","Gene description":"Uronyl 2-sulfotransferase","Uniprot":["Q9Y2C2"],"Chromosome":"6","Position":"148747030-149076990","Protein class":["Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"325.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"15.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"2.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Fibroblasts","Liver - Hepatic stellate cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032022"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 27: TE 441.T - Unknown function","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA032022":"AB_10603326"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"}},{"Gene":"UTS2R","Gene synonym":["GPR14"],"Ensembl":"ENSG00000181408","Gene description":"Urotensin 2 receptor","Uniprot":["Q9UKP6"],"Chromosome":"17","Position":"82371400-82375586","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.5","testis":"3.2","thyroid gland":"1.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"stomach cancer":"0.7","testis cancer":"2.2","thyroid cancer":"1.1"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"1.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"lymphoma":"7.2","Myeloma":"12.1"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 34: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"VAMP1","Gene synonym":["SYB1","VAMP-1"],"Ensembl":"ENSG00000139190","Gene description":"Vesicle associated membrane protein 1","Uniprot":["P23763"],"Chromosome":"12","Position":"6462237-6470677","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Congenital myasthenic syndrome","Disease variant","FDA approved drug targets","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"192.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"22.3","Inhibitory neurons":"24.5","Oligodendrocytes":"25.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lymphoma":"53.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002779","CAB016119","CAB079000"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 1: T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002779":null,"CAB016119":"AB_628309","CAB079000":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.37e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.97e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"}},{"Gene":"VAMP2","Gene synonym":["SYB2","VAMP-2"],"Ensembl":"ENSG00000220205","Gene description":"Vesicle associated membrane protein 2","Uniprot":["P63027"],"Chromosome":"17","Position":"8159149-8163546","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","FDA approved drug targets","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"1051.7","Cone photoreceptor cells":"1142.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB078785"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB078785":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.08e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.83e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.76e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"}},{"Gene":"VAMP3","Gene synonym":["CEB"],"Ensembl":"ENSG00000049245","Gene description":"Vesicle associated membrane protein 3","Uniprot":["Q15836"],"Chromosome":"1","Position":"7771296-7781432","Protein class":["Cancer-related genes","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"}},{"Gene":"VAMP4","Gene synonym":[],"Ensembl":"ENSG00000117533","Gene description":"Vesicle associated membrane protein 4","Uniprot":["O75379"],"Chromosome":"1","Position":"171700160-171742074","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050418"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 18: Non-specific - RNA binding","Single cell expression cluster":"Cluster 42: Spermatocytes & Spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA050418":"AB_2681121"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.43e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"}},{"Gene":"VAMP5","Gene synonym":[],"Ensembl":"ENSG00000168899","Gene description":"Vesicle associated membrane protein 5","Uniprot":["O95183"],"Chromosome":"2","Position":"85584431-85593406","Protein class":["Predicted membrane proteins"],"Biological process":["Differentiation","Myogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"503.4","Endothelial cells":"357.5","Melanocytes":"329.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Kidney - Endothelial cells","Prostate - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035082"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA035082":"AB_10610564"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.28e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"}},{"Gene":"VAMP7","Gene synonym":["SYBL1","TI-VAMP","VAMP-7"],"Ensembl":"ENSG00000124333","Gene description":"Vesicle associated membrane protein 7","Uniprot":["P51809"],"Chromosome":"X","Position":"155881345-155943769","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Exocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036733"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA036733":"AB_10672228"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"}},{"Gene":"VAMP8","Gene synonym":["EDB"],"Ensembl":"ENSG00000118640","Gene description":"Vesicle associated membrane protein 8","Uniprot":["Q9BV40"],"Chromosome":"2","Position":"85561562-85582031","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiviral defense","Autophagy","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"1216.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Breast - Breast glandular cells","Heart muscle - Macrophages","Skeletal muscle - Macrophages","Skin - Keratinocyte (other)","Stomach - Gastric mucous cells","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006882","HPA007215","CAB037132","CAB037147"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB037132":"AB_1080547","CAB037147":"AB_1080544","HPA006882":"AB_1858716","HPA007215":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.07e-9"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.59e-6"}},{"Gene":"VANGL1","Gene synonym":["STB2"],"Ensembl":"ENSG00000173218","Gene description":"VANGL planar cell polarity protein 1","Uniprot":["Q8TAA9"],"Chromosome":"1","Position":"115641970-115698224","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"6.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"2.3","NK-cells":"6.2","T-cells":"3.0"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Mitotic cells (Skin)","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025235","CAB076375"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB076375":"AB_2665604","HPA025235":"AB_1858718"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.53e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.89e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-3"}},{"Gene":"VANGL2","Gene synonym":["KIAA1215","LPP1","LTAP","MGC119403","MGC119404","STB1","STBM","STBM1"],"Ensembl":"ENSG00000162738","Gene description":"VANGL planar cell polarity protein 2","Uniprot":["Q9ULK5"],"Chromosome":"1","Position":"160400564-160428670","Protein class":["Disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"37.6"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"35.9","testis cancer":"36.7"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027043"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027043":"AB_10601709"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"}},{"Gene":"VAPA","Gene synonym":["hVAP-33","VAP-A"],"Ensembl":"ENSG00000101558","Gene description":"VAMP associated protein A","Uniprot":["Q9P0L0"],"Chromosome":"18","Position":"9914016-9960021","Protein class":["Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009174"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"580000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA009174":"AB_1080549"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.72e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"}},{"Gene":"VAPB","Gene synonym":["ALS8","VAP-B","VAP-C"],"Ensembl":"ENSG00000124164","Gene description":"VAMP associated protein B and C","Uniprot":["O95292"],"Chromosome":"20","Position":"58389229-58451101","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction","Unfolded protein response"],"Molecular function":null,"Disease involvement":["Amyotrophic lateral sclerosis","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013144","CAB013722"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB013722":null,"HPA013144":"AB_1858717"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.08e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"}},{"Gene":"VARS1","Gene synonym":["VARS","VARS2"],"Ensembl":"ENSG00000204394","Gene description":"Valyl-tRNA synthetase 1","Uniprot":["P26640"],"Chromosome":"6","Position":"31777518-31795752","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"138.6","Late spermatids":"263.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046710"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 15: Non-specific - Protein binding","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046710":"AB_2679765"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.25e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.90e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"}},{"Gene":"VARS2","Gene synonym":["DKFZP434L1435","G7a","KIAA1885","VARS2L","VARSL"],"Ensembl":"ENSG00000137411","Gene description":"Valyl-tRNA synthetase 2, mitochondrial","Uniprot":["Q5ST30"],"Chromosome":"6","Position":"30914205-30926459","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Protein biosynthesis"],"Molecular function":["Aminoacyl-tRNA synthetase","Ligase"],"Disease involvement":["Disease variant","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"14.2","Excitatory neurons":"8.2","Inhibitory neurons":"8.9","Microglial cells":"3.6","Oligodendrocyte precursor cells":"7.7","Oligodendrocytes":"6.7","Plasma cells":"4.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062449","HPA070267"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 9: Lymphoid cancers - Immune response","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA062449":"AB_2684766","HPA070267":"AB_2686245"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"}},{"Gene":"VASH1","Gene synonym":["KIAA1036"],"Ensembl":"ENSG00000071246","Gene description":"Vasohibin 1","Uniprot":["Q7L8A9"],"Chromosome":"14","Position":"76761468-76783015","Protein class":["Enzymes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell cycle","Growth arrest"],"Molecular function":["Carboxypeptidase","Hydrolase","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"67.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"91.3","Early spermatids":"54.6","Late spermatids":"102.2","Microglial cells":"52.0","Rod photoreceptor cells":"110.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000653"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000653":"AB_1080551"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.56e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"}},{"Gene":"VASN","Gene synonym":["SLITL2"],"Ensembl":"ENSG00000168140","Gene description":"Vasorin","Uniprot":["Q6EMK4"],"Chromosome":"16","Position":"4371848-4383538","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"57.4","Fibroblasts":"71.6","Leydig cells":"48.5","Peritubular cells":"61.7","Sertoli cells":"66.3","Smooth muscle cells":"70.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011246","HPA016992"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Mitochondria"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 72: Smooth muscle cells - ECM organization","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Nucleoli"],"Antibody RRID":{"HPA011246":"AB_1858720","HPA016992":"AB_2732418"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.24e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.91e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"}},{"Gene":"VCAM1","Gene synonym":["CD106"],"Ensembl":"ENSG00000162692","Gene description":"Vascular cell adhesion molecule 1","Uniprot":["P19320"],"Chromosome":"1","Position":"100719742-100739045","Protein class":["Cancer-related genes","CD markers","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"389.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"140.7","Endothelial cells":"61.3","Macrophages":"49.2","Proximal tubular cells":"168.9","Theca cells":"139.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"renal cancer":"89.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bladder cancer":"33.4","Kidney cancer":"59.2","thyroid cancer":"42.8"},"RNA tissue cell type enrichment":["Stomach - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000154","HPA034796","HPA069867"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":624000000,"Blood concentration - Conc. blood MS [pg\/L]":"1300000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB000154":null,"HPA034796":"AB_2674333","HPA069867":"AB_2686215"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.82e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.19e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"}},{"Gene":"VCP","Gene synonym":["CDC48","IBMPFD","p97","TERA"],"Ensembl":"ENSG00000165280","Gene description":"Valosin containing protein","Uniprot":["P55072"],"Chromosome":"9","Position":"35053928-35072668","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Autophagy","DNA damage","DNA repair","Transport","Ubl conjugation pathway"],"Molecular function":["Hydrolase"],"Disease involvement":["Amyotrophic lateral sclerosis","Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"603.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005593","HPA012728","HPA012814"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000000","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005593":"AB_2214638","HPA012728":"AB_1858730","HPA012814":"AB_1858729"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.30e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.63e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"}},{"Gene":"VEGFA","Gene synonym":["VEGF","VEGF-A","VPF"],"Ensembl":"ENSG00000112715","Gene description":"Vascular endothelial growth factor A","Uniprot":["P15692"],"Chromosome":"6","Position":"43770184-43786487","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Angiogenesis","Differentiation"],"Molecular function":["Developmental protein","Growth factor","Heparin-binding","Mitogen"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"243.8","Langerhans cells":"275.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"renal cancer":"79.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Podocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005429","CAB039240","HPA069116","CAB069907"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":562000,"Blood concentration - Conc. blood MS [pg\/L]":"57000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB005429":"AB_2212984","CAB039240":null,"CAB069907":"AB_10001947","HPA069116":"AB_2686089"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.50e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.10e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.34e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.76e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.73e-4"}},{"Gene":"VEZT","Gene synonym":["DKFZP761C241"],"Ensembl":"ENSG00000028203","Gene description":"Vezatin, adherens junctions transmembrane protein","Uniprot":["Q9HBM0"],"Chromosome":"12","Position":"95217746-95302799","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004811","HPA017066"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA004811":"AB_1080563","HPA017066":"AB_1858742"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.71e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.93e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.68e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"}},{"Gene":"VIPR1","Gene synonym":["HVR1","RDC1","VPAC1","VPAC1R"],"Ensembl":"ENSG00000114812","Gene description":"Vasoactive intestinal peptide receptor 1","Uniprot":["P32241"],"Chromosome":"3","Position":"42489299-42537573","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"132.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"40.1","Distal enterocytes":"49.5","Intestinal goblet cells":"50.0","Paneth cells":"90.8","Proximal enterocytes":"45.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"10.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"dendritic cells":"2.1","monocytes":"1.8","T-cells":"2.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Colon enterocytes","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"amygdala":"6.3","basal ganglia":"4.5","cerebral cortex":"9.6","hippocampal formation":"7.7","white matter":"2.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026777"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA026777":"AB_10604003"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"}},{"Gene":"VIPR2","Gene synonym":["VPAC2","VPAC2R"],"Ensembl":"ENSG00000106018","Gene description":"Vasoactive intestinal peptide receptor 2","Uniprot":["P41587"],"Chromosome":"7","Position":"159028175-159144867","Protein class":["G-protein coupled receptors","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"66.5","Muller glia cells":"32.7","Oligodendrocyte precursor cells":"47.7","Rod photoreceptor cells":"43.9","Thymic epithelial cells":"98.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"17","RNA blood cell specific nTPM":{"plasmacytoid DC":"12.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"dendritic cells":"12.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"5.3"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Mesothelial cells","Skeletal muscle - Skeletal myocytes","Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"27.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062707"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Focal adhesion sites"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Focal adhesion sites"],"Subcellular additional location":null,"Antibody RRID":{"HPA062707":"AB_2684842"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"}},{"Gene":"VKORC1","Gene synonym":["VKCFD2"],"Ensembl":"ENSG00000167397","Gene description":"Vitamin K epoxide reductase complex subunit 1","Uniprot":["Q9BQB6"],"Chromosome":"16","Position":"31090842-31095980","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"454.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"337.9","Hepatocytes":"776.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042720"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 20: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 13: Hepatocytes - Oxidoreductase activity","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA042720":"AB_10961864"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.09e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"}},{"Gene":"VKORC1L1","Gene synonym":[],"Ensembl":"ENSG00000196715","Gene description":"Vitamin K epoxide reductase complex subunit 1 like 1","Uniprot":["Q8N0U8"],"Chromosome":"7","Position":"65873074-65959563","Protein class":["Enzymes","FDA approved drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"94.9","Alveolar cells type 2":"92.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053954"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 31: Non-specific - Transcription","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA053954":"AB_2682319"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"}},{"Gene":"VLDLR","Gene synonym":["CARMQ1","CHRMQ1","VLDLRCH"],"Ensembl":"ENSG00000147852","Gene description":"Very low density lipoprotein receptor","Uniprot":["P98155"],"Chromosome":"9","Position":"2621182-2660056","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol metabolism","Endocytosis","Host-virus interaction","Lipid metabolism","Lipid transport","Steroid metabolism","Sterol metabolism","Transport"],"Molecular function":["Receptor"],"Disease involvement":["Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"77.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"67.4","Cone photoreceptor cells":"93.1","Rod photoreceptor cells":"55.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"eosinophil":"6.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"6.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032462","HPA051312"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytokinetic bridge","Centriolar satellite"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"330000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytokinetic bridge","Centriolar satellite"],"Antibody RRID":{"CAB032462":"AB_2216805","HPA051312":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.95e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"}},{"Gene":"VMA21","Gene synonym":["MEAX","XMEA"],"Ensembl":"ENSG00000160131","Gene description":"Vacuolar ATPase assembly factor VMA21","Uniprot":["Q3ZAQ7"],"Chromosome":"X","Position":"151396515-151409364","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"158.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010972"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA010972":"AB_1853034"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.30e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"}},{"Gene":"VMP1","Gene synonym":["EPG3","TANGO5","TMEM49"],"Ensembl":"ENSG00000062716","Gene description":"Vacuole membrane protein 1","Uniprot":["Q96GC9"],"Chromosome":"17","Position":"59707192-59842255","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Autophagy","Cell adhesion","Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"3000.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"3000.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030773","HPA064780"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 22: Squamous epithelial cells - Keratinization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA030773":"AB_10602248","HPA064780":"AB_2685348"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.56e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.02e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.77e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-3"}},{"Gene":"VN1R1","Gene synonym":["V1RL1","VNR19I1","ZVNH1","ZVNR1"],"Ensembl":"ENSG00000178201","Gene description":"Vomeronasal 1 receptor 1","Uniprot":["Q9GZP7"],"Chromosome":"19","Position":"57454790-57457142","Protein class":["G-protein coupled receptors","Predicted membrane proteins","Transporters"],"Biological process":["Pheromone response"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"8.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"2.6","Cone photoreceptor cells":"1.7","dendritic cells":"1.8","Horizontal cells":"4.5","Oligodendrocyte precursor cells":"2.4","Rod photoreceptor cells":"2.6","Skeletal myocytes":"4.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062209"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 54: Non-specific - Microtubule organization","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA062209":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-5"}},{"Gene":"VN1R2","Gene synonym":["V1RL2"],"Ensembl":"ENSG00000196131","Gene description":"Vomeronasal 1 receptor 2","Uniprot":["Q8NFZ6"],"Chromosome":"19","Position":"53258292-53261837","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Pheromone response"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"19","RNA single cell type specific nTPM":{"Early spermatids":"12.7","Late spermatids":"11.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044551"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044551":"AB_2678982"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"VN1R4","Gene synonym":["V1RL4"],"Ensembl":"ENSG00000228567","Gene description":"Vomeronasal 1 receptor 4","Uniprot":["Q7Z5H5"],"Chromosome":"19","Position":"53266676-53267723","Protein class":["G-protein coupled receptors","Predicted membrane proteins"],"Biological process":["Pheromone response"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027018"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027018":"AB_10603142"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"VNN1","Gene synonym":["Tiff66"],"Ensembl":"ENSG00000112299","Gene description":"Vanin 1","Uniprot":["O95497"],"Chromosome":"6","Position":"132680849-132714055","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"gallbladder":"89.2","intestine":"136.3","liver":"218.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"55.8","Ductal cells":"241.7","Exocrine glandular cells":"49.3","Glandular and luminal cells":"48.2","Hepatocytes":"68.3","monocytes":"95.2","Proximal enterocytes":"52.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"41.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"13.7","non-classical monocyte":"11.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"80","RNA blood lineage specific nTPM":{"dendritic cells":"5.0","granulocytes":"8.5","monocytes":"13.7"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"13.7","pancreatic cancer":"10.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Colon - Macrophages","Kidney - Proximal tubular cells","Lung - Neutrophil_2"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"white matter":"2.4"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046103","HPA064145"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"980000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046103":null,"HPA064145":"AB_2685197"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"}},{"Gene":"VNN2","Gene synonym":["FOAP-4","GPI-80"],"Ensembl":"ENSG00000112303","Gene description":"Vanin 2","Uniprot":["O95498"],"Chromosome":"6","Position":"132743870-132763459","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"31.6","lymphoid tissue":"56.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"61.1","Hofbauer cells":"26.4","Kupffer cells":"43.0","Macrophages":"37.9","monocytes":"30.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"477.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"477.4"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"lymphoma":"24.5"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Heart muscle - Neutrophils","Liver - Neutrophils","Lung - Neutrophil_2","Skeletal muscle - Neutrophils","Testis - Macrophages","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.72e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"}},{"Gene":"VNN3","Gene synonym":["HSA238982"],"Ensembl":"ENSG00000093134","Gene description":"Vanin 3","Uniprot":["Q9NY84"],"Chromosome":"6","Position":"132722787-132736935","Protein class":["Enzymes","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"34.9","liver":"34.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"25.2","Club cells":"21.4","Gastric mucus-secreting cells":"15.5","Ionocytes":"66.6","Respiratory ciliated cells":"93.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"3.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"76.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"granulocytes":"76.2"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"head and neck cancer":"2.5"},"RNA tissue cell type enrichment":["Adipose visceral - Neutrophils","Colon - Neutrophils","Heart muscle - Neutrophils","Skeletal muscle - Neutrophils","Stomach - Neutrophils","Thyroid - Neutrophils"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":150000000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"}},{"Gene":"VOPP1","Gene synonym":["DKFZp564K0822","ECop","FLJ20532","GASP","WBP1L2"],"Ensembl":"ENSG00000154978","Gene description":"VOPP1 WW domain binding protein","Uniprot":["Q96AW1"],"Chromosome":"7","Position":"55436056-55572988","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"251.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"391.2","Langerhans cells":"173.2","Plasma cells":"279.7","Rod photoreceptor cells":"216.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"56.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.35e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.99e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"}},{"Gene":"VPS11","Gene synonym":["PEP5","RNF108"],"Ensembl":"ENSG00000160695","Gene description":"VPS11 core subunit of CORVET and HOPS complexes","Uniprot":["Q9H270"],"Chromosome":"11","Position":"119067818-119081972","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Autophagy","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Dystonia","Leukodystrophy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039020"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039020":"AB_10674847"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"}},{"Gene":"VPS13B","Gene synonym":["CHS1","COH1"],"Ensembl":"ENSG00000132549","Gene description":"Vacuolar protein sorting 13 homolog B","Uniprot":["Q7Z7G8"],"Chromosome":"8","Position":"99013266-99877580","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"155.9","Excitatory neurons":"231.7","Inhibitory neurons":"247.3","Microglial cells":"198.8","Oligodendrocyte precursor cells":"207.9","Oligodendrocytes":"224.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043865"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"HPA043865":"AB_2678704"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"}},{"Gene":"VPS13D","Gene synonym":["FLJ10619","KIAA0453"],"Ensembl":"ENSG00000048707","Gene description":"Vacuolar protein sorting 13 homolog D","Uniprot":["Q5THJ4"],"Chromosome":"1","Position":"12230030-12512047","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"178.9","Inhibitory neurons":"146.0","Late spermatids":"202.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027332","HPA051621"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 38: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA027332":"AB_2672223","HPA051621":"AB_2681555"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.42e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"}},{"Gene":"VPS29","Gene synonym":["DC15","DC7","PEP11"],"Ensembl":"ENSG00000111237","Gene description":"VPS29 retromer complex component","Uniprot":["Q9UBQ0"],"Chromosome":"12","Position":"110491083-110502111","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Transporters"],"Biological process":["Host-virus interaction","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039748"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039748":"AB_10674426"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.79e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.70e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"}},{"Gene":"VPS33A","Gene synonym":[],"Ensembl":"ENSG00000139719","Gene description":"VPS33A core subunit of CORVET and HOPS complexes","Uniprot":["Q96AX1"],"Chromosome":"12","Position":"122229564-122266494","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Autophagy","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Mucopolysaccharidosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038701"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA038701":"AB_10673473"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.11e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.41e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"}},{"Gene":"VPS33B","Gene synonym":["FLJ14848"],"Ensembl":"ENSG00000184056","Gene description":"VPS33B late endosome and lysosome associated","Uniprot":["Q9H267"],"Chromosome":"15","Position":"90998673-91022603","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040415"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040415":"AB_10795419"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"}},{"Gene":"VPS35L","Gene synonym":["C16orf62","MGC16824"],"Ensembl":"ENSG00000103544","Gene description":"VPS35 endosomal protein sorting factor like","Uniprot":["Q7Z3J2"],"Chromosome":"16","Position":"19555240-19706793","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"107.4","Late spermatids":"116.5","Oligodendrocytes":"143.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042969","HPA053547"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA042969":"AB_10794920","HPA053547":"AB_2682183"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.31e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"}},{"Gene":"VPS51","Gene synonym":["ANG2","ANG3","C11orf2","C11orf3","FFR"],"Ensembl":"ENSG00000149823","Gene description":"VPS51 subunit of GARP complex","Uniprot":["Q9UID3"],"Chromosome":"11","Position":"65089324-65111862","Protein class":["Disease related genes","Predicted intracellular proteins"],"Biological process":["Lipid transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039650","HPA061447"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA039650":"AB_10673147","HPA061447":"AB_2684521"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.41e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"}},{"Gene":"VPS52","Gene synonym":["ARE1","SACM2L"],"Ensembl":"ENSG00000223501","Gene description":"VPS52 subunit of GARP complex","Uniprot":["Q8N1B4"],"Chromosome":"6","Position":"33250272-33272047","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042667","HPA048128"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042667":"AB_2678105","HPA048128":"AB_2680278"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"}},{"Gene":"VRK1","Gene synonym":[],"Ensembl":"ENSG00000100749","Gene description":"VRK serine\/threonine kinase 1","Uniprot":["Q99986"],"Chromosome":"14","Position":"96797304-96954846","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Cell division","Host-virus interaction","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"50.4","testis":"37.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"102.5","Spermatocytes":"233.6","Spermatogonia":"116.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000660","HPA017929"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA000660":"AB_1080579","HPA017929":"AB_1858770"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"}},{"Gene":"VRK2","Gene synonym":[],"Ensembl":"ENSG00000028116","Gene description":"VRK serine\/threonine kinase 2","Uniprot":["Q86Y07"],"Chromosome":"2","Position":"57907629-58159920","Protein class":["Enzymes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Oligodendrocytes":"510.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB046459","HPA047503"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB046459":"AB_1858773","HPA047503":"AB_2680071"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.32e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.65e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.66e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"}},{"Gene":"VSIG1","Gene synonym":["GPA34","MGC44287"],"Ensembl":"ENSG00000101842","Gene description":"V-set and immunoglobulin domain containing 1","Uniprot":["Q86XK7"],"Chromosome":"X","Position":"108044970-108079184","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"stomach 1":"193.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"29","RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"315.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"lung cancer":"8.7","pancreatic cancer":"17.7","stomach cancer":"31.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"12.0","T-reg":"12.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"12.9"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"16.8","pancreatic cancer":"7.4"},"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001445","HPA036310","HPA036311"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001445":"AB_10669749","HPA036310":"AB_10670795","HPA036311":"AB_10673350"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"}},{"Gene":"VSIG10","Gene synonym":[],"Ensembl":"ENSG00000176834","Gene description":"V-set and immunoglobulin domain containing 10","Uniprot":["Q8N0Z9"],"Chromosome":"12","Position":"118063593-118136026","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"105.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062022"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA062022":"AB_2732675"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.76e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.53e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"}},{"Gene":"VSIG10L","Gene synonym":[],"Ensembl":"ENSG00000186806","Gene description":"V-set and immunoglobulin domain containing 10 like","Uniprot":["Q86VR7"],"Chromosome":"19","Position":"51331536-51342124","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"20.3","esophagus":"62.3","salivary gland":"23.5","vagina":"22.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Serous glandular cells":"18.8","Suprabasal keratinocytes":"44.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"liver cancer":"6.4"},"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060453","HPA066745"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 61: Liver - Metabolism","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA060453":"AB_2684280","HPA066745":"AB_2685712"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.75e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"}},{"Gene":"VSIG2","Gene synonym":["CTH","CTXL"],"Ensembl":"ENSG00000019102","Gene description":"V-set and immunoglobulin domain containing 2","Uniprot":["Q96IQ7"],"Chromosome":"11","Position":"124747474-124752255","Protein class":["Predicted membrane proteins"],"Biological process":["Lipid metabolism"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"stomach 1":"619.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Club cells":"180.4","Distal enterocytes":"581.0","Gastric mucus-secreting cells":"618.9","Intestinal goblet cells":"235.4","Paneth cells":"367.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"87.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"20.4"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Breast - Breast glandular cells","Colon - Colon enterocytes","Liver - Cholangiocyte","Lung - Alveolar cells type 1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035919","HPA050147"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"78000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 4: Stomach - Digestion","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA035919":"AB_10669981","HPA050147":"AB_2681032"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"}},{"Gene":"VSIG4","Gene synonym":["CRIg","Z39IG"],"Ensembl":"ENSG00000155659","Gene description":"V-set and immunoglobulin domain containing 4","Uniprot":["Q9Y279"],"Chromosome":"X","Position":"66021738-66040125","Protein class":["Plasma proteins","Predicted membrane proteins"],"Biological process":["Complement alternate pathway","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"166.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"884.4","Kupffer cells":"409.6","Langerhans cells":"148.0","Macrophages":"445.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"88.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"27","RNA blood cell specific nTPM":{"classical monocyte":"18.7","intermediate monocyte":"11.1","myeloid DC":"17.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"31","RNA blood lineage specific nTPM":{"dendritic cells":"17.8","monocytes":"18.7"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"29","RNA cell line specific nTPM":{"Leukemia":"2.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Breast - Macrophages","Colon - Macrophages","Heart muscle - Macrophages","Kidney - Macrophages","Liver - Kupffer cells","Lung - Macrophages","Pancreas - Macrophages","Prostate - Macrophages","Skeletal muscle - Macrophages","Skin - Macrophages","Stomach - Macrophages","Thyroid - Macrophages"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003903","CAB026000","HPA072756"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoli","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"59000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB026000":null,"HPA003903":"AB_1858776","HPA072756":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.95e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"}},{"Gene":"VSIG8","Gene synonym":[],"Ensembl":"ENSG00000243284","Gene description":"V-set and immunoglobulin domain containing 8","Uniprot":["P0DPA2"],"Chromosome":"1","Position":"159854316-159862657","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"25.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"143.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"4.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"1.5"},"RNA tissue cell type enrichment":["Kidney - Podocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023219"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"650000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 3: Suprabasal keratinocytes - Cornification","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023219":"AB_1845635"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"}},{"Gene":"VSIR","Gene synonym":["B7-H5","B7H5","C10orf54","Dies1","GI24","PD-1H","SISP1","VISTA"],"Ensembl":"ENSG00000107738","Gene description":"V-set immunoregulatory receptor","Uniprot":["Q9H7M9"],"Chromosome":"10","Position":"71747556-71773520","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"90.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"319.0","Extravillous trophoblasts":"339.4","Kupffer cells":"354.5","monocytes":"437.2","Syncytiotrophoblasts":"694.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1006.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Neutrophil_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007968"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA007968":"AB_1845518"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.93e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"}},{"Gene":"VSTM1","Gene synonym":["UNQ3033"],"Ensembl":"ENSG00000189068","Gene description":"V-set and transmembrane domain containing 1","Uniprot":["Q6UX27"],"Chromosome":"19","Position":"54040825-54063953","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity"],"Molecular function":["Cytokine"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"bone marrow":"43.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"17.2","Late spermatids":"20.2","Macrophages":"5.0","monocytes":"17.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"eosinophil":"129.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"granulocytes":"129.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.1"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059365"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059365":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"}},{"Gene":"VSTM2A","Gene synonym":["MGC33530","VSTM2"],"Ensembl":"ENSG00000170419","Gene description":"V-set and transmembrane domain containing 2A","Uniprot":["Q8TAG5"],"Chromosome":"7","Position":"54542325-54571080","Protein class":["Plasma proteins","Predicted secreted proteins"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"10.2","brain":"31.3","prostate":"9.7","retina":"14.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"37.4","Excitatory neurons":"12.4","Fibroblasts":"7.1","Horizontal cells":"17.9","Inhibitory neurons":"29.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"4.6","glioma":"3.0"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"31.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Neuroblastoma":"7.2","prostate cancer":"5.0","thyroid cancer":"5.3"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"31000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.34e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"}},{"Gene":"VSTM2B","Gene synonym":[],"Ensembl":"ENSG00000187135","Gene description":"V-set and transmembrane domain containing 2B","Uniprot":["A6NLU5"],"Chromosome":"19","Position":"29526499-29564479","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"46.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"24.9","Excitatory neurons":"55.1","Horizontal cells":"30.8","Inhibitory neurons":"36.9","Oligodendrocyte precursor cells":"93.4","Oligodendrocytes":"215.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"3.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"1.2","Neuroblastoma":"1.2"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"VSTM4","Gene synonym":["C10orf72","FLJ31737"],"Ensembl":"ENSG00000165633","Gene description":"V-set and transmembrane domain containing 4","Uniprot":["Q8IW00"],"Chromosome":"10","Position":"49014236-49115522","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"61.0","Granulosa cells":"96.1","Late spermatids":"153.1","Theca cells":"40.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"thyroid cancer":"22.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"7.6"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Lung - Fibroblast_1","Prostate - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Fibroblast_1"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017279"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA017279":"AB_10959519"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.25e-4"}},{"Gene":"VSTM5","Gene synonym":["C11orf90","LOC387804"],"Ensembl":"ENSG00000214376","Gene description":"V-set and transmembrane domain containing 5","Uniprot":["A8MXK1"],"Chromosome":"11","Position":"93818232-93850618","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"3.7","placenta":"4.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"21.4","Excitatory neurons":"5.1","Gastric mucus-secreting cells":"3.6","Inhibitory neurons":"9.0","Syncytiotrophoblasts":"4.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"prostate cancer":"4.8"},"RNA tissue cell type enrichment":["Kidney - Proximal tubular cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029525","HPA063591"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 24: Prostate cancer - Lipid metabolism","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA029525":"AB_10600789","HPA063591":"AB_2732704"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"}},{"Gene":"VTCN1","Gene synonym":["B7-H4","B7H4","B7S1","B7x","FLJ22418"],"Ensembl":"ENSG00000134258","Gene description":"V-set domain containing T cell activation inhibitor 1","Uniprot":["Q7Z7D3"],"Chromosome":"1","Position":"117143587-117210960","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"100.9","fallopian tube":"32.7","pancreas":"30.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"59.9","Club cells":"29.8","Collecting duct cells":"45.3","Ductal cells":"76.4","Endometrial ciliated cells":"41.4","Glandular and luminal cells":"80.8","Mucus glandular cells":"63.7","Salivary duct cells":"31.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"breast cancer":"55.8","endometrial cancer":"45.2","ovarian cancer":"49.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"43.8","ovarian cancer":"40.3","testis cancer":"29.9"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Lung - Respiratory ciliated cells","Prostate - Urothelial cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054200"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 5: Breast - Unknown function","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 73: Prostatic glandular cells - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions","Focal adhesion sites"],"Antibody RRID":{"HPA054200":"AB_2682415"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"}},{"Gene":"VTI1A","Gene synonym":["MVti1","Vti1-rp2"],"Ensembl":"ENSG00000151532","Gene description":"Vesicle transport through interaction with t-SNAREs 1A","Uniprot":["Q96AJ9"],"Chromosome":"10","Position":"112446998-112818744","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"131.0","Excitatory neurons":"241.2","Inhibitory neurons":"195.0","Late spermatids":"101.5","Microglial cells":"190.6","Oligodendrocyte precursor cells":"165.1","Oligodendrocytes":"206.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054108"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA054108":"AB_2682382"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.50e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.27e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"}},{"Gene":"VTI1B","Gene synonym":["VTI2"],"Ensembl":"ENSG00000100568","Gene description":"Vesicle transport through interaction with t-SNAREs 1B","Uniprot":["Q9UEU0"],"Chromosome":"14","Position":"67647085-67674820","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"491.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044121","HPA048150","HPA060118"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA044121":"AB_2678819","HPA048150":"AB_2680288","HPA060118":"AB_2684206"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.53e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-3"}},{"Gene":"VWA3A","Gene synonym":["FLJ40941","FLJ46765"],"Ensembl":"ENSG00000175267","Gene description":"Von Willebrand factor A domain containing 3A","Uniprot":["A6NCI4"],"Chromosome":"16","Position":"22092538-22156964","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"28.2","choroid plexus":"53.0","fallopian tube":"39.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"24.7","Early spermatids":"13.1","Endometrial ciliated cells":"33.8","Excitatory neurons":"33.2","Late spermatids":"13.5","Respiratory ciliated cells":"68.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"endometrial cancer":"3.2","glioma":"1.4","ovarian cancer":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bile duct cancer":"2.4"},"RNA tissue cell type enrichment":["Lung - Respiratory ciliated cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041696","HPA042044"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA041696":"AB_10964202","HPA042044":"AB_10968997"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.15e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-4"}},{"Gene":"VWA7","Gene synonym":["C6orf27","G7c","NG37"],"Ensembl":"ENSG00000204396","Gene description":"Von Willebrand factor A domain containing 7","Uniprot":["Q9Y334"],"Chromosome":"6","Position":"31765590-31777328","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"21.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"7.8","Paneth cells":"2.1","Proximal enterocytes":"4.8","Proximal tubular cells":"2.5","Respiratory ciliated cells":"2.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"2.9","hypothalamus":"8.2","medulla oblongata":"5.9","pons":"5.5","thalamus":"7.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Cardiomyocytes","Lung - Respiratory ciliated cells","Stomach - Gastric mucous cells"],"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"cerebellum":"7.0","pons and medulla":"3.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046954","HPA054262"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9200","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 29: TT & NCI-H1385 - Synaptic signal transduction","Single cell expression cluster":"Cluster 58: Gastric mucus-secreting cells - Digestion","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046954":"AB_2679875","HPA054262":"AB_2682430"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.35e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"}},{"Gene":"WAC","Gene synonym":["BM-016","FLJ31290","MGC10753","PRO1741","Wwp4"],"Ensembl":"ENSG00000095787","Gene description":"WW domain containing adaptor with coiled-coil","Uniprot":["Q9BTA9"],"Chromosome":"10","Position":"28532493-28623112","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036528","HPA042609","HPA074604"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA036528":"AB_10670839","HPA042609":"AB_2678076","HPA074604":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.27e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"WBP1","Gene synonym":["WBP-1"],"Ensembl":"ENSG00000239779","Gene description":"WW domain binding protein 1","Uniprot":["Q96G27"],"Chromosome":"2","Position":"74458400-74460891","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"29.1","Gastric mucus-secreting cells":"32.8","Plasma cells":"44.4","Squamous epithelial cells":"29.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057067"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA057067":"AB_2683326"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.83e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.36e-4"}},{"Gene":"WBP1L","Gene synonym":["C10orf26","FLJ20154","OPAL1"],"Ensembl":"ENSG00000166272","Gene description":"WW domain binding protein 1 like","Uniprot":["Q9NX94"],"Chromosome":"10","Position":"102743948-102834516","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Late spermatids":"579.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037635","HPA038371"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Microtubules"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA037635":"AB_10672462","HPA038371":"AB_2675980"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.03e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.56e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"}},{"Gene":"WDFY3","Gene synonym":["ALFY","KIAA0993","ZFYVE25"],"Ensembl":"ENSG00000163625","Gene description":"WD repeat and FYVE domain containing 3","Uniprot":["Q8IZQ1"],"Chromosome":"4","Position":"84669597-84966690","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"44.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"233.4","Excitatory neurons":"227.6","Inhibitory neurons":"242.8","Microglial cells":"204.3","Oligodendrocyte precursor cells":"251.7","Oligodendrocytes":"415.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042734","HPA048572"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli","Plasma membrane"],"Antibody RRID":{"HPA042734":"AB_2678135","HPA048572":"AB_2680447"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.64e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.35e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"}},{"Gene":"WDFY4","Gene synonym":["C10orf64","Em:AC060234.3","FLJ45748","KIAA1607"],"Ensembl":"ENSG00000128815","Gene description":"WDFY family member 4","Uniprot":["Q6ZS81"],"Chromosome":"10","Position":"48684876-48982956","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"11.7","lymphoid tissue":"28.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"59.8","dendritic cells":"88.8","Early spermatids":"57.7","Microglial cells":"79.4","Schwann cells":"190.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"memory B-cell":"14.3","myeloid DC":"11.3","naive B-cell":"21.2","neutrophil":"10.2","plasmacytoid DC":"32.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"21.2","dendritic cells":"32.5","granulocytes":"10.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Leukemia":"12.9","lymphoma":"36.9"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Adipose visceral - Macrophages","Lung - Macrophages","Stomach - Macrophages","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040634"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA040634":"AB_10795491"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-2"}},{"Gene":"WDHD1","Gene synonym":["AND-1","CHTF4","CTF4"],"Ensembl":"ENSG00000198554","Gene description":"WD repeat and HMG-box DNA binding protein 1","Uniprot":["O75717"],"Chromosome":"14","Position":"54938949-55027105","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"8.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"16.6","Spermatogonia":"17.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"23.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Mitotic cells (Lung)","Skin - Mitotic cells (Skin)","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000632","HPA001122"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA000632":null,"HPA001122":"AB_1080589"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.24e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"}},{"Gene":"WDR11","Gene synonym":["BRWD2","DR11","FLJ10506","HH14","KIAA1351","SRI1","WDR15"],"Ensembl":"ENSG00000120008","Gene description":"WD repeat domain 11","Uniprot":["Q9BZH6"],"Chromosome":"10","Position":"120851305-120909524","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hypogonadotropic hypogonadism","Kallmann syndrome","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038980"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Microtubules","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA038980":"AB_10675955"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.04e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"}},{"Gene":"WDR17","Gene synonym":[],"Ensembl":"ENSG00000150627","Gene description":"WD repeat domain 17","Uniprot":["Q8IZU2"],"Chromosome":"4","Position":"176065841-176182818","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"11.5","retina":"28.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"177.5","Cone photoreceptor cells":"46.5","Excitatory neurons":"219.6","Inhibitory neurons":"124.6","Oligodendrocyte precursor cells":"119.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Smooth muscle cells","Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042766","HPA054501"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042766":"AB_10806372","HPA054501":"AB_2732586"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-3"}},{"Gene":"WDR20","Gene synonym":["DMR","FLJ33659","MGC33177"],"Ensembl":"ENSG00000140153","Gene description":"WD repeat domain 20","Uniprot":["Q8TBZ3"],"Chromosome":"14","Position":"102139503-102224847","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"185.8","Late spermatids":"290.4","Oligodendrocytes":"190.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.26e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"}},{"Gene":"WDR33","Gene synonym":["FLJ11294","NET14","WDC146"],"Ensembl":"ENSG00000136709","Gene description":"WD repeat domain 33","Uniprot":["Q9C0J8"],"Chromosome":"2","Position":"127701027-127811187","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["mRNA processing"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026897","HPA046527"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA026897":"AB_1858803","HPA046527":"AB_2679686"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.13e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"}},{"Gene":"WDR45","Gene synonym":["JM5","NBIA5","WDRX1","WIPI4"],"Ensembl":"ENSG00000196998","Gene description":"WD repeat domain 45","Uniprot":["Q9Y484"],"Chromosome":"X","Position":"49074433-49101170","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027562"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 60: Proximal tubular cells - Absorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027562":"AB_10610565"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.21e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.61e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"}},{"Gene":"WDR81","Gene synonym":["CAMRQ2","FLJ33817","PPP1R166","SORF-2"],"Ensembl":"ENSG00000167716","Gene description":"WD repeat domain 81","Uniprot":["Q562E7"],"Chromosome":"17","Position":"1716523-1738599","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Macrophages"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023044","HPA063703"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"HPA023044":"AB_1858822","HPA063703":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.30e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"}},{"Gene":"WDR83OS","Gene synonym":["Asterix","C19orf56","PTD008"],"Ensembl":"ENSG00000105583","Gene description":"WD repeat domain 83 opposite strand","Uniprot":["Q9Y284"],"Chromosome":"19","Position":"12668073-12669415","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Gastric mucus-secreting cells":"16.1","Oligodendrocytes":"37.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065685"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 61: Non-specific - Transcription","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA065685":"AB_2685531"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.09e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.84e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"}},{"Gene":"WDR97","Gene synonym":["KIAA1875"],"Ensembl":"ENSG00000179698","Gene description":"WD repeat domain 97","Uniprot":["A6NE52"],"Chromosome":"8","Position":"144107726-144118328","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"testis":"1.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"6.6","Horizontal cells":"7.0","Rod photoreceptor cells":"7.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059409"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059409":"AB_2684005"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-4"}},{"Gene":"WFDC11","Gene synonym":["WAP11"],"Ensembl":"ENSG00000180083","Gene description":"WAP four-disulfide core domain 11","Uniprot":["Q8NEX6"],"Chromosome":"20","Position":"45648563-45670270","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"epididymis":"93.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"25","RNA single cell type specific nTPM":{"Early spermatids":"34.6","Late spermatids":"22.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"basophil":"2.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"2.3"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"WFDC8","Gene synonym":["C20orf170","dJ461P17.1","WAP8"],"Ensembl":"ENSG00000158901","Gene description":"WAP four-disulfide core domain 8","Uniprot":["Q8IUA0"],"Chromosome":"20","Position":"45551153-45579326","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"518","RNA tissue specific nTPM":{"epididymis":"410.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042710","HPA071119"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA042710":"AB_2732501","HPA071119":"AB_2732172"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Urothelial cancer":null},{"Gene":"WFDC9","Gene synonym":["dJ688G8.2","WAP9"],"Ensembl":"ENSG00000180205","Gene description":"WAP four-disulfide core domain 9","Uniprot":["Q8NEX5"],"Chromosome":"20","Position":"45607939-45631284","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"464","RNA tissue specific nTPM":{"epididymis":"989.3"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in male reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"WFS1","Gene synonym":["DFNA14","DFNA38","DFNA6","DIDMOAD","WFS"],"Ensembl":"ENSG00000109501","Gene description":"Wolframin ER transmembrane glycoprotein","Uniprot":["O76024"],"Chromosome":"4","Position":"6269849-6303265","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cataract","Deafness","Diabetes insipidus","Diabetes mellitus","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"98.1","Extravillous trophoblasts":"130.8","Granulosa cells":"70.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 1","Prostate - Smooth muscle cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029128"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029128":"AB_10603460"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.13e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"}},{"Gene":"WHAMM","Gene synonym":["KIAA1971","WHAMM1","WHDC1"],"Ensembl":"ENSG00000156232","Gene description":"WASP homolog associated with actin, golgi membranes and microtubules","Uniprot":["Q8TF30"],"Chromosome":"15","Position":"82809628-82836108","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"29.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039690","HPA040231"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039690":"AB_10795405","HPA040231":"AB_10795361"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.09e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.31e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-2"}},{"Gene":"WHRN","Gene synonym":["CIP98","DFNB31","PDZD7B","USH2D"],"Ensembl":"ENSG00000095397","Gene description":"Whirlin","Uniprot":["Q9P202"],"Chromosome":"9","Position":"114402080-114505473","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Hearing"],"Molecular function":null,"Disease involvement":["Deafness","Non-syndromic deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"104.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"68.3","Endometrial ciliated cells":"45.8","Late spermatids":"213.2","Oligodendrocytes":"81.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"46.5"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Heart muscle - Fibroblasts","Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.28e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"}},{"Gene":"WIPI2","Gene synonym":["ATG18B","ATG21","CGI-50","DKFZP434J154","DKFZp686P02188","FLJ12979","FLJ14217","FLJ42984"],"Ensembl":"ENSG00000157954","Gene description":"WD repeat domain, phosphoinositide interacting 2","Uniprot":["Q9Y4P8"],"Chromosome":"7","Position":"5190196-5233840","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Autophagy"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"252.6","Spermatocytes":"231.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019852","HPA021488"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA019852":"AB_1846589","HPA021488":"AB_1846591"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.69e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.78e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.05e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"}},{"Gene":"WLS","Gene synonym":["C1orf139","EVI","FLJ23091","GPR177","mig-14","MRP"],"Ensembl":"ENSG00000116729","Gene description":"Wnt ligand secretion mediator","Uniprot":["Q5T9L3"],"Chromosome":"1","Position":"68098473-68233120","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"175.8","Glandular and luminal cells":"248.7","Rod photoreceptor cells":"176.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"classical monocyte":"22.1","neutrophil":"61.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"46","RNA blood lineage specific nTPM":{"granulocytes":"61.7","monocytes":"22.1"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"357.0"},"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069520"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA069520":"AB_2686144"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.03e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.43e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.67e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.51e-4"}},{"Gene":"WNK2","Gene synonym":["KIAA1760","NY-CO-43","PRKWNK2","SDCCAG43"],"Ensembl":"ENSG00000165238","Gene description":"WNK lysine deficient protein kinase 2","Uniprot":["Q9Y3S1"],"Chromosome":"9","Position":"93184916-93320572","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"83.1","skeletal muscle":"62.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"74.0","Excitatory neurons":"126.7","Inhibitory neurons":"96.6","Rod photoreceptor cells":"112.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Heart muscle - Cardiomyocytes","Lung - Respiratory ciliated cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015555","HPA016519","CAB017813"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB017813":null,"HPA015555":"AB_2669218","HPA016519":"AB_2669380"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"}},{"Gene":"WNT10A","Gene synonym":[],"Ensembl":"ENSG00000135925","Gene description":"Wnt family member 10A","Uniprot":["Q9GZT5"],"Chromosome":"2","Position":"218880852-218899581","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant","Ectodermal dysplasia","Hypotrichosis","Palmoplantar keratoderma"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"7.0","skin 1":"8.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"19.0","Basal respiratory cells":"15.0","Basal squamous epithelial cells":"17.2","Bipolar cells":"11.2","Collecting duct cells":"21.7","dendritic cells":"36.5","Plasma cells":"20.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"17.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"plasmacytoid DC":"6.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"6.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"39.6"},"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Stomach - Plasma cells","Testis - Early spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"5.2"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"basal ganglia":"2.1"},"Antibody":["HPA013898"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 60: Keratinocytes - Epithelial cell function","Single cell expression cluster":"Cluster 45: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013898":"AB_1858847"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"}},{"Gene":"WNT10B","Gene synonym":["SHFM6","WNT-12"],"Ensembl":"ENSG00000169884","Gene description":"Wnt family member 10B","Uniprot":["O00744"],"Chromosome":"12","Position":"48965340-48971735","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"17.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"7.2","Extravillous trophoblasts":"26.7","Fibroblasts":"4.6","Inhibitory neurons":"4.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"17.5"},"RNA tissue cell type enrichment":["Kidney - T-cells","Prostate - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055048"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 54: Extravillous trophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA055048":"AB_2682683"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"}},{"Gene":"WNT2B","Gene synonym":["WNT13","XWNT2"],"Ensembl":"ENSG00000134245","Gene description":"Wnt family member 2B","Uniprot":["Q93097"],"Chromosome":"1","Position":"112466541-112530165","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Leydig cells":"83.3","Peritubular cells":"193.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"4.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Testis - Peritubular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047274","HPA066368"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 68: Kidney - Mixed function","Single cell expression cluster":"Cluster 53: Connective tissue cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA047274":"AB_2732539","HPA066368":"AB_2685664"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"}},{"Gene":"WSCD2","Gene synonym":["KIAA0789"],"Ensembl":"ENSG00000075035","Gene description":"WSC domain containing 2","Uniprot":["Q2TBF2"],"Chromosome":"12","Position":"108129288-108250537","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"36.7","thyroid gland":"16.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Bipolar cells":"35.4","Excitatory neurons":"29.7","Horizontal cells":"21.8","Inhibitory neurons":"27.0","Oligodendrocyte precursor cells":"9.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"2.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pancreas - Beta cells","Prostate - Smooth muscle cells","Skeletal muscle - Fibroblasts","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013346","HPA048133"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 35: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA013346":"AB_1858865","HPA048133":"AB_2797236"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-3"}},{"Gene":"WWC2","Gene synonym":["BOMB","FLJ22029"],"Ensembl":"ENSG00000151718","Gene description":"WW and C2 domain containing 2","Uniprot":["Q6AWC2"],"Chromosome":"4","Position":"183099257-183320777","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"228.1","Inhibitory neurons":"95.8","Microglial cells":"125.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Alveolar cells type 1","Skin - Endothelial cells","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044005"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA044005":"AB_10960552"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.61e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"}},{"Gene":"WWOX","Gene synonym":["FOR","SDR41C1","WOX1"],"Ensembl":"ENSG00000186153","Gene description":"WW domain containing oxidoreductase","Uniprot":["Q9NZC7"],"Chromosome":"16","Position":"78099430-79212667","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Wnt signaling pathway"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","Epilepsy","Neurodegeneration","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Astrocytes":"899.0","Excitatory neurons":"266.4","Inhibitory neurons":"528.7","Microglial cells":"458.8","Oligodendrocyte precursor cells":"876.1","Oligodendrocytes":"749.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050992"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA050992":"AB_2681299"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.07e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"}},{"Gene":"WWP1","Gene synonym":["AIP5","DKFZP434D2111"],"Ensembl":"ENSG00000123124","Gene description":"WW domain containing E3 ubiquitin protein ligase 1","Uniprot":["Q9H0M0"],"Chromosome":"8","Position":"86342547-86478420","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"171.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023180"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Cytosol"],"Subcellular additional location":["Golgi apparatus","Plasma membrane"],"Antibody RRID":{"HPA023180":"AB_10602587"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"}},{"Gene":"XBP1","Gene synonym":["XBP2"],"Ensembl":"ENSG00000100219","Gene description":"X-box binding protein 1","Uniprot":["P17861"],"Chromosome":"22","Position":"28794555-28800597","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Angiogenesis","Apoptosis","Autophagy","Differentiation","Lipid biosynthesis","Lipid metabolism","Myogenesis","Protein transport","Stress response","Transcription","Transcription regulation","Transport","Unfolded protein response"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"1159.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"1715.4","Plasma cells":"2575.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"662.2"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Liver - Hepatocytes","Lung - Alveolar cells type 2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"XCR1","Gene synonym":["CCXCR1","GPR5"],"Ensembl":"ENSG00000173578","Gene description":"X-C motif chemokine receptor 1","Uniprot":["P46094"],"Chromosome":"3","Position":"46017007-46027487","Protein class":["G-protein coupled receptors","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"11.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Schwann cells":"32.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"myeloid DC":"3.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"3.8"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"2.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013169"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA013169":"AB_1846211"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"}},{"Gene":"XG","Gene synonym":["PBDX"],"Ensembl":"ENSG00000124343","Gene description":"Xg glycoprotein (Xg blood group)","Uniprot":["P55808"],"Chromosome":"X","Position":"2752040-2816500","Protein class":["Blood group antigen proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Blood group antigen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"17.5","skin 1":"38.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"15.9","Basal respiratory cells":"13.8","Basal squamous epithelial cells":"16.1","Fibroblasts":"24.3","Squamous epithelial cells":"9.7","Suprabasal keratinocytes":"26.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"6.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Bone cancer":"35.8"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"22000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 65: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.25e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-3"}},{"Gene":"XK","Gene synonym":["Kx","NA","NAC","X1k","XKR1"],"Ensembl":"ENSG00000047597","Gene description":"X-linked Kx blood group","Uniprot":["P51811"],"Chromosome":"X","Position":"37685791-37732130","Protein class":["Blood group antigen proteins","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Amino-acid transport","Transport"],"Molecular function":["Blood group antigen"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"14.2","intestine":"12.2","stomach 1":"11.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"24.1","Enteroendocrine cells":"13.9","Erythroid cells":"34.2","Gastric mucus-secreting cells":"17.9","Proximal enterocytes":"20.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"6.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"53","RNA blood cell specific nTPM":{"basophil":"10.2","eosinophil":"5.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"102","RNA blood lineage specific nTPM":{"granulocytes":"10.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"11.7"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Smooth muscle cells","Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019036"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA019036":"AB_1846286"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"}},{"Gene":"XKR3","Gene synonym":["MGC57211","XTES"],"Ensembl":"ENSG00000172967","Gene description":"XK related 3","Uniprot":["Q5GH77"],"Chromosome":"22","Position":"16783412-16821699","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"43","RNA tissue specific nTPM":{"testis":"8.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Early spermatids":"202.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"1.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bladder cancer":"1.9","Myeloma":"7.1"},"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003379","HPA035081"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA003379":"AB_10602682","HPA035081":"AB_2674451"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-1"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"XKR4","Gene synonym":["KIAA1889"],"Ensembl":"ENSG00000206579","Gene description":"XK related 4","Uniprot":["Q5GH76"],"Chromosome":"8","Position":"55102028-55542054","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"8.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Excitatory neurons":"301.5","Inhibitory neurons":"995.8","Oligodendrocyte precursor cells":"690.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Bone cancer":"5.1"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Colon - Enteric glia cells","Stomach - Fibroblasts","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025072","HPA028083"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 28: Bone cancer CADO-ES1 - Glutamate signalling","Single cell expression cluster":"Cluster 37: Neurons - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA025072":"AB_1858886","HPA028083":"AB_10601025"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"}},{"Gene":"XKR5","Gene synonym":[],"Ensembl":"ENSG00000275591","Gene description":"XK related 5","Uniprot":["Q6UX68"],"Chromosome":"8","Position":"6808517-6835524","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Bone cancer":"2.0","Neuroblastoma":"3.0"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"}},{"Gene":"XKR6","Gene synonym":["C8orf21","C8orf5","C8orf7"],"Ensembl":"ENSG00000171044","Gene description":"XK related 6","Uniprot":["Q5GH73"],"Chromosome":"8","Position":"10896045-11201833","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"12.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"87.3","Excitatory neurons":"412.9","Inhibitory neurons":"331.8","Microglial cells":"104.0","Oligodendrocyte precursor cells":"277.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024828","HPA064769"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 64: Lymphoma - Humoral immune response","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Actin filaments"],"Subcellular additional location":null,"Antibody RRID":{"HPA024828":"AB_2215165","HPA064769":"AB_2732720"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-3"}},{"Gene":"XKR7","Gene synonym":["C20orf159","dJ310O13.4"],"Ensembl":"ENSG00000260903","Gene description":"XK related 7","Uniprot":["Q5GH72"],"Chromosome":"20","Position":"31968151-32003387","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"brain":"8.9","pituitary gland":"4.3","retina":"4.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"3.6","Collecting duct cells":"2.0","Cone photoreceptor cells":"5.2","Early spermatids":"2.3","Excitatory neurons":"4.4","Horizontal cells":"3.8","Inhibitory neurons":"4.7","Late spermatids":"2.0","Rod photoreceptor cells":"3.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"8.9"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"lung cancer":"4.2","Neuroblastoma":"10.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells","Pancreas - Alpha cells","Pancreas - Beta cells","Stomach - Gastric enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"12.3"},"Antibody":["HPA040854"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040854":"AB_10795481"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"}},{"Gene":"XKR8","Gene synonym":["FLJ10307"],"Ensembl":"ENSG00000158156","Gene description":"XK related 8","Uniprot":["Q9H6D3"],"Chromosome":"1","Position":"27959588-27968093","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"62.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"eosinophil":"202.8","neutrophil":"101.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"granulocytes":"202.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049984","HPA053529"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 6: BEWO - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA049984":"AB_2680982","HPA053529":"AB_2682179"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.63e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"}},{"Gene":"XKR9","Gene synonym":[],"Ensembl":"ENSG00000221947","Gene description":"XK related 9","Uniprot":["Q5GH70"],"Chromosome":"8","Position":"70669339-70790371","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"5.3","testis":"7.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"41.4","Inhibitory neurons":"17.4","Oligodendrocytes":"21.7","Spermatocytes":"79.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044430"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA044430":"AB_10961283"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.20e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"}},{"Gene":"XKRX","Gene synonym":["XKR2","XPLAC"],"Ensembl":"ENSG00000182489","Gene description":"XK related X-linked","Uniprot":["Q6PP77"],"Chromosome":"X","Position":"100913445-100929433","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"9.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"5.0","Alveolar cells type 2":"3.4","Astrocytes":"9.2","Excitatory neurons":"4.3","Inhibitory neurons":"5.9","Microglial cells":"3.6","Oligodendrocytes":"5.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"naive B-cell":"1.9","naive CD4 T-cell":"1.5","naive CD8 T-cell":"1.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"B-cells":"1.9","T-cells":"1.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (granular)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 46: Non-specific - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.52e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"}},{"Gene":"XPNPEP2","Gene synonym":[],"Ensembl":"ENSG00000122121","Gene description":"X-prolyl aminopeptidase 2","Uniprot":["O43895"],"Chromosome":"X","Position":"129738949-129769536","Protein class":["Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Aminopeptidase","Hydrolase","Metalloprotease","Protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"166.6","kidney":"156.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Proximal enterocytes":"420.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"18.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"gdT-cell":"4.3","intermediate monocyte":"1.4","MAIT T-cell":"1.2","memory CD4 T-cell":"1.3","memory CD8 T-cell":"2.8","naive CD8 T-cell":"2.0","non-classical monocyte":"2.8","T-reg":"1.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"monocytes":"2.8","T-cells":"4.3"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Leukemia":"1.0"},"RNA tissue cell type enrichment":["Breast - Macrophages","Heart muscle - Fibroblasts","Kidney - Proximal tubular cells","Kidney - Proximal tubular cells","Lung - Fibroblast_2","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000339","CAB025136","CAB025269","HPA064568"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 59: Fibroblasts - Metabolism","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB025136":null,"CAB025269":null,"HPA000339":"AB_1858894","HPA064568":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-3"}},{"Gene":"XPO7","Gene synonym":["KIAA0745","RANBP16"],"Ensembl":"ENSG00000130227","Gene description":"Exportin 7","Uniprot":["Q9UIA9"],"Chromosome":"8","Position":"21919662-22006585","Protein class":["Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043727","HPA048153"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"53000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 71: Erythroid cells - Oxygen transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043727":"AB_2678638","HPA048153":"AB_2680289"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"}},{"Gene":"XPR1","Gene synonym":["SLC53A1","SYG1","X3"],"Ensembl":"ENSG00000143324","Gene description":"Xenotropic and polytropic retrovirus receptor 1","Uniprot":["Q9UBH6"],"Chromosome":"1","Position":"180632022-180890279","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"97.7","Excitatory neurons":"116.4","Inhibitory neurons":"100.3","Microglial cells":"99.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016557"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016557":"AB_2669382"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.04e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.44e-2"}},{"Gene":"XXYLT1","Gene synonym":["C3orf21","FLJ35155"],"Ensembl":"ENSG00000173950","Gene description":"Xyloside xylosyltransferase 1","Uniprot":["Q8NBI6"],"Chromosome":"3","Position":"195068284-195271159","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"30.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"10.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 66: Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"}},{"Gene":"YAF2","Gene synonym":[],"Ensembl":"ENSG00000015153","Gene description":"YY1 associated factor 2","Uniprot":["Q8IY57"],"Chromosome":"12","Position":"42157104-42238349","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026867"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 69: BICR 18 - Unknown function","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA026867":"AB_1858911"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"}},{"Gene":"YEATS4","Gene synonym":["GAS41","NuBI-1","YAF9"],"Ensembl":"ENSG00000127337","Gene description":"YEATS domain containing 4","Uniprot":["O95619"],"Chromosome":"12","Position":"69359710-69390870","Protein class":["Predicted intracellular proteins"],"Biological process":["Growth regulation","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Spermatocytes":"360.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072532"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 31: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"HPA072532":"AB_2686530"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.52e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"}},{"Gene":"YIF1A","Gene synonym":["54TM","FinGER7","YIF1","YIF1P"],"Ensembl":"ENSG00000174851","Gene description":"Yip1 interacting factor homolog A, membrane trafficking protein","Uniprot":["O95070"],"Chromosome":"11","Position":"66284580-66289145","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014840","HPA076194"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA014840":"AB_2217189","HPA076194":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.70e-4"}},{"Gene":"YIF1B","Gene synonym":["FinGER8"],"Ensembl":"ENSG00000167645","Gene description":"Yip1 interacting factor homolog B, membrane trafficking protein","Uniprot":["Q5BJH7"],"Chromosome":"19","Position":"38303558-38317273","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039328","HPA055257","HPA062675"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"37000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA039328":"AB_2676445","HPA055257":"AB_2682762","HPA062675":"AB_2684830"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.53e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.88e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-3"}},{"Gene":"YIPF1","Gene synonym":["DJ167A19.1","FinGER1"],"Ensembl":"ENSG00000058799","Gene description":"Yip1 domain family member 1","Uniprot":["Q9Y548"],"Chromosome":"1","Position":"53851719-53889798","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"80.6","Syncytiotrophoblasts":"135.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Prostate - Prostate glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014716","HPA073931"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 28: Cytotrophoblasts - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA014716":"AB_1847686","HPA073931":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-1"}},{"Gene":"YIPF2","Gene synonym":["FinGER2","MGC3262"],"Ensembl":"ENSG00000130733","Gene description":"Yip1 domain family member 2","Uniprot":["Q9BWQ6"],"Chromosome":"19","Position":"10922185-10928681","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"158.4","Spermatocytes":"146.6","Syncytiotrophoblasts":"198.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019902"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA019902":"AB_1858925"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"}},{"Gene":"YIPF3","Gene synonym":["C6orf109","dJ337H4.3","DKFZp566C243","FinGER3","KLIP1"],"Ensembl":"ENSG00000137207","Gene description":"Yip1 domain family member 3","Uniprot":["Q9GZM5"],"Chromosome":"6","Position":"43511832-43516985","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Testis - Sertoli cells","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014859","HPA063699"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 37: Ovarian cancer RMG-I - Cellular stress response","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA014859":"AB_1845729","HPA063699":"AB_2685095"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"}},{"Gene":"YIPF4","Gene synonym":["FinGER4","MGC11061"],"Ensembl":"ENSG00000119820","Gene description":"Yip1 domain family member 4","Uniprot":["Q9BSR8"],"Chromosome":"2","Position":"32277904-32316594","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"129.1","choroid plexus":"65.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"240.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017884"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"HPA017884":"AB_1853855"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"}},{"Gene":"YIPF5","Gene synonym":["FinGER5","SMAP-5"],"Ensembl":"ENSG00000145817","Gene description":"Yip1 domain family member 5","Uniprot":["Q969M3"],"Chromosome":"5","Position":"144158162-144170714","Protein class":["Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Diabetes mellitus","Disease variant","Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042338","HPA073622"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Endoplasmic reticulum","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 57: Non-specific - Translation","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Endoplasmic reticulum","Golgi apparatus","Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA042338":"AB_2677953","HPA073622":"AB_2686618"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.83e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.26e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"}},{"Gene":"YIPF6","Gene synonym":["FinGER6","MGC21416"],"Ensembl":"ENSG00000181704","Gene description":"Yip1 domain family member 6","Uniprot":["Q96EC8"],"Chromosome":"X","Position":"68498562-68537282","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"336.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003720"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 67: Syncytiotrophoblasts - Pregnancy","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA003720":"AB_1080626"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"}},{"Gene":"YIPF7","Gene synonym":["FinGER9","FLJ39576"],"Ensembl":"ENSG00000177752","Gene description":"Yip1 domain family member 7","Uniprot":["Q8N8F6"],"Chromosome":"4","Position":"44622065-44678556","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"skeletal muscle":"84.9","tongue":"27.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Skeletal myocytes":"25.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030642"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 27: Skeletal myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030642":"AB_10601027"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"}},{"Gene":"YME1L1","Gene synonym":["YME1L"],"Ensembl":"ENSG00000136758","Gene description":"YME1 like 1 ATPase","Uniprot":["Q96TA2"],"Chromosome":"10","Position":"27110111-27155266","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066953"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA066953":"AB_2685753"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.25e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"}},{"Gene":"Z84492.1","Gene synonym":[],"Ensembl":"ENSG00000272104","Gene description":"Novel protein","Uniprot":[],"Chromosome":"3","Position":"50350892-50367923","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ZACN","Gene synonym":["L2","LGICZ","LGICZ1","ZAC","ZAC1"],"Ensembl":"ENSG00000186919","Gene description":"Zinc activated ion channel","Uniprot":["Q401N2"],"Chromosome":"17","Position":"76071961-76083666","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 2: T-cells - T-cell receptor","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"}},{"Gene":"ZAN","Gene synonym":[],"Ensembl":"ENSG00000146839","Gene description":"Zonadhesin","Uniprot":["Q9Y493"],"Chromosome":"7","Position":"100733595-100797797","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"14.5","Late spermatids":"13.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"testis cancer":"1.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":null,"Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"}},{"Gene":"ZAP70","Gene synonym":["SRK","STD","ZAP-70"],"Ensembl":"ENSG00000115085","Gene description":"Zeta chain of T cell receptor associated protein kinase 70","Uniprot":["P43403"],"Chromosome":"2","Position":"97713576-97739862","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"24.8","lymphoid tissue":"79.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"NK-cells":"143.0","T-cells":"100.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"41","RNA blood cell specific nTPM":{"gdT-cell":"137.4","MAIT T-cell":"93.2","memory CD4 T-cell":"71.7","memory CD8 T-cell":"108.3","naive CD4 T-cell":"50.8","naive CD8 T-cell":"79.8","NK-cell":"112.2","T-reg":"80.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"56","RNA blood lineage specific nTPM":{"NK-cells":"112.2","T-cells":"137.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Leukemia":"39.9","lymphoma":"13.5","Rhabdoid":"13.0"},"RNA tissue cell type enrichment":["Adipose subcutaneous - T-cells","Adipose visceral - T-cells","Breast - T-cells","Colon - T-cells","Heart muscle - T-cells","Kidney - T-cells","Prostate - T-cells","Skin - T-cells","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002625","HPA003134"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 7: NK-cells - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002625":null,"HPA003134":"AB_1080629"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.89e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.66e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"}},{"Gene":"ZBTB11","Gene synonym":["ZNF-U69274","ZNF913"],"Ensembl":"ENSG00000066422","Gene description":"Zinc finger and BTB domain containing 11","Uniprot":["O95625"],"Chromosome":"3","Position":"101648889-101677132","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015328","HPA024138"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015328":"AB_1858938","HPA024138":"AB_1858939"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.49e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"}},{"Gene":"ZBTB40","Gene synonym":["KIAA0478","ZNF923"],"Ensembl":"ENSG00000184677","Gene description":"Zinc finger and BTB domain containing 40","Uniprot":["Q9NUA8"],"Chromosome":"1","Position":"22428838-22531157","Protein class":["Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042386"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA042386":"AB_10794649"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.01e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.78e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.12e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"}},{"Gene":"ZC2HC1A","Gene synonym":["C8orf70","CGI-62","FAM164A"],"Ensembl":"ENSG00000104427","Gene description":"Zinc finger C2HC-type containing 1A","Uniprot":["Q96GY0"],"Chromosome":"8","Position":"78666089-78719765","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"44.6"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"45.1","T-reg":"33.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024726"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Cytosol"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"HPA024726":"AB_1846597"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.00e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.85e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"}},{"Gene":"ZCCHC17","Gene synonym":["HSPC251","pNO40","PS1D"],"Ensembl":"ENSG00000121766","Gene description":"Zinc finger CCHC-type containing 17","Uniprot":["Q9NP64"],"Chromosome":"1","Position":"31296982-31364953","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"272.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053727"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 33: Skin cancer - Membrane components","Single cell expression cluster":"Cluster 4: Platelets - Platelet activation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA053727":"AB_2732581"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.72e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"}},{"Gene":"ZDHHC1","Gene synonym":["C16orf1","HSU90653","ZNF377"],"Ensembl":"ENSG00000159714","Gene description":"Zinc finger DHHC-type containing 1","Uniprot":["Q8WTX9"],"Chromosome":"16","Position":"67394152-67416833","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"86.3","Late spermatids":"50.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"1.4","non-classical monocyte":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Lung - Respiratory ciliated cells","Skin - Fibroblast_2"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042531","HPA048659"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042531":"AB_2678041","HPA048659":"AB_2680483"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.99e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.55e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-3"}},{"Gene":"ZDHHC11","Gene synonym":["FLJ13153","ZNF399"],"Ensembl":"ENSG00000188818","Gene description":"Zinc finger DHHC-type containing 11","Uniprot":["Q9H8X9"],"Chromosome":"5","Position":"795606-850986","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"18.5","Endometrial ciliated cells":"17.0","Excitatory neurons":"21.1","Inhibitory neurons":"16.0","Oligodendrocytes":"17.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057886","HPA069008"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA057886":"AB_2683548","HPA069008":"AB_2686068"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"}},{"Gene":"ZDHHC11B","Gene synonym":[],"Ensembl":"ENSG00000206077","Gene description":"Zinc finger DHHC-type containing 11B","Uniprot":["P0C7U3"],"Chromosome":"5","Position":"710355-784729","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"brain":"29.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"46.6","Inhibitory neurons":"37.4","Oligodendrocyte precursor cells":"25.5","Oligodendrocytes":"66.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Gastric cancer":"3.7"},"RNA tissue cell type enrichment":["Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057886","HPA069008"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 19: Stomach & Colon cancer - Absorption","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA057886":"AB_2683548","HPA069008":"AB_2686068"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.98e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"}},{"Gene":"ZDHHC12","Gene synonym":["FLJ14524","ZNF400"],"Ensembl":"ENSG00000160446","Gene description":"Zinc finger DHHC-type palmitoyltransferase 12","Uniprot":["Q96GR4"],"Chromosome":"9","Position":"128720870-128724127","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"251.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059339"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Intermediate filaments"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 55: Non-specific - Unknown function","Single cell expression cluster":"Cluster 74: Pancreatic cells - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Intermediate filaments"],"Antibody RRID":{"HPA059339":"AB_2683985"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"}},{"Gene":"ZDHHC13","Gene synonym":["FLJ10852","FLJ10941","HIP14L"],"Ensembl":"ENSG00000177054","Gene description":"Zinc finger DHHC-type palmitoyltransferase 13","Uniprot":["Q8IUH4"],"Chromosome":"11","Position":"19117099-19176422","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"125.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Vascular Endothelial cells","Prostate - Urothelial cells","Stomach - Gastric mucous cells","Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016759","HPA018791"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 3: HUVEC & TIME - Signal transduction","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA016759":"AB_1858993","HPA018791":"AB_1858992"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"}},{"Gene":"ZDHHC14","Gene synonym":["FLJ20984","NEW1CP"],"Ensembl":"ENSG00000175048","Gene description":"Zinc finger DHHC-type palmitoyltransferase 14","Uniprot":["Q8IZN3"],"Chromosome":"6","Position":"157381133-157678157","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"22.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"159.4","Horizontal cells":"81.4","Inhibitory neurons":"105.6","Oligodendrocyte precursor cells":"301.8","Oligodendrocytes":"208.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells","Thyroid - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013437","HPA063754"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 10: Neurons & Oligodendrocytes - Nervous system development","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA013437":null,"HPA063754":"AB_2685113"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.78e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.93e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"}},{"Gene":"ZDHHC15","Gene synonym":["DHHC15","FLJ31812","MRX91"],"Ensembl":"ENSG00000102383","Gene description":"Zinc finger DHHC-type palmitoyltransferase 15","Uniprot":["Q96MV8"],"Chromosome":"X","Position":"75368427-75523502","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"14.6","Collecting duct cells":"9.8","Excitatory neurons":"17.9","Inhibitory neurons":"17.3","Oligodendrocyte precursor cells":"16.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"2.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"2.1","Rhabdoid":"2.2"},"RNA tissue cell type enrichment":["Liver - Hepatic stellate cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003618","HPA064901"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 21: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA003618":"AB_2217686","HPA064901":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-4"}},{"Gene":"ZDHHC16","Gene synonym":["APH2"],"Ensembl":"ENSG00000171307","Gene description":"Zinc finger DHHC-type palmitoyltransferase 16","Uniprot":["Q969W1"],"Chromosome":"10","Position":"97446170-97457370","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","DNA damage"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"74.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039893","HPA040214"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear membrane","Cytosol"],"Antibody RRID":{"HPA039893":"AB_10794757","HPA040214":"AB_2676886"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"}},{"Gene":"ZDHHC17","Gene synonym":["HIP14","HYPH","KIAA0946"],"Ensembl":"ENSG00000186908","Gene description":"Zinc finger DHHC-type palmitoyltransferase 17","Uniprot":["Q8IUH5"],"Chromosome":"12","Position":"76764103-76853696","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"112.5","Excitatory neurons":"100.8","Inhibitory neurons":"92.9","Oligodendrocytes":"109.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"17.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016807"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 48: Plasmacytoid dendritic cells - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA016807":"AB_1858999"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.11e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"}},{"Gene":"ZDHHC18","Gene synonym":["DKFZp667O2416"],"Ensembl":"ENSG00000204160","Gene description":"Zinc finger DHHC-type palmitoyltransferase 18","Uniprot":["Q9NUE0"],"Chromosome":"1","Position":"26826688-26857604","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"113.9"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"48.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"granulocytes":"48.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040234"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 33: Macrophages - Degranulation","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"HPA040234":"AB_10805709"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.15e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.42e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.36e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"}},{"Gene":"ZDHHC19","Gene synonym":["MGC33345"],"Ensembl":"ENSG00000163958","Gene description":"Zinc finger DHHC-type palmitoyltransferase 19","Uniprot":["Q8WVZ1"],"Chromosome":"3","Position":"196197452-196211437","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"32","RNA tissue specific nTPM":{"testis":"50.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"19","RNA single cell type specific nTPM":{"Early spermatids":"290.2","Late spermatids":"822.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"19","RNA blood cell specific nTPM":{"eosinophil":"1.2","memory B-cell":"2.5","naive B-cell":"2.4","neutrophil":"1.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"20","RNA blood lineage specific nTPM":{"B-cells":"2.5","granulocytes":"1.5"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Neutrophils","Lung - Neutrophil_2","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 10: Ovarian & Endometrial cancers - Unknown function","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"}},{"Gene":"ZDHHC2","Gene synonym":["DHHC2","ZNF372"],"Ensembl":"ENSG00000104219","Gene description":"Zinc finger DHHC-type palmitoyltransferase 2","Uniprot":["Q9UIJ5"],"Chromosome":"8","Position":"17156482-17224799","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"77.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"85.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023331","HPA023334"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 34: Rabdoid cancer - Embryonic development","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA023331":"AB_2671165","HPA023334":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"}},{"Gene":"ZDHHC20","Gene synonym":["DHHC20","FLJ25952"],"Ensembl":"ENSG00000180776","Gene description":"Zinc finger DHHC-type palmitoyltransferase 20","Uniprot":["Q5W0Z9"],"Chromosome":"13","Position":"21372571-21459370","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"95.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"410.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014483","HPA014702"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA014483":"AB_1859000","HPA014702":"AB_1859001"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.55e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.01e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"}},{"Gene":"ZDHHC21","Gene synonym":["DHHC21","DNZ1","HSPC097"],"Ensembl":"ENSG00000175893","Gene description":"Zinc finger DHHC-type palmitoyltransferase 21","Uniprot":["Q8IVQ6"],"Chromosome":"9","Position":"14611071-14693432","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"216.2","Inhibitory neurons":"196.8","Oligodendrocyte precursor cells":"257.5","Oligodendrocytes":"149.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065254"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA065254":"AB_2685446"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.28e-6"}},{"Gene":"ZDHHC22","Gene synonym":["C14orf59"],"Ensembl":"ENSG00000177108","Gene description":"Zinc finger DHHC-type palmitoyltransferase 22","Uniprot":["Q8N966"],"Chromosome":"14","Position":"77131270-77142734","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"51.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"15.4","Excitatory neurons":"8.6","Horizontal cells":"12.2","Inhibitory neurons":"13.0","Late spermatids":"5.0","Oligodendrocyte precursor cells":"23.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"40","RNA cancer specific FPKM":{"glioma":"7.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Brain cancer":"4.6","Neuroblastoma":"9.7"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049471","HPA072213"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 47: Retina - Visual perception","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA049471":"AB_2732553","HPA072213":"AB_2686496"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-1"}},{"Gene":"ZDHHC23","Gene synonym":["MGC42530"],"Ensembl":"ENSG00000184307","Gene description":"Zinc finger DHHC-type palmitoyltransferase 23","Uniprot":["Q8IYP9"],"Chromosome":"3","Position":"113947901-113965401","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"24.6","Excitatory neurons":"71.2","Late spermatids":"40.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"9","RNA brain regional specific nTPM":{"amygdala":"5.4","basal ganglia":"7.3","cerebral cortex":"9.4","hippocampal formation":"7.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016808"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 43: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA016808":"AB_1859002"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.85e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.48e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.90e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-3"}},{"Gene":"ZDHHC24","Gene synonym":[],"Ensembl":"ENSG00000174165","Gene description":"Zinc finger DHHC-type containing 24","Uniprot":["Q6UX98"],"Chromosome":"11","Position":"66520637-66546235","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016619"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 19: Macrophages - Innate immune response","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA016619":"AB_2288672"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.28e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.99e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"}},{"Gene":"ZDHHC3","Gene synonym":["DHHC3","GODZ","ZNF373"],"Ensembl":"ENSG00000163812","Gene description":"Zinc finger DHHC-type palmitoyltransferase 3","Uniprot":["Q9NYG2"],"Chromosome":"3","Position":"44915257-44976185","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Early spermatids":"431.7","Late spermatids":"1598.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Breast - Adipocytes (Breast)","Skin - Keratinocyte (other)","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012465","HPA016616"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB012465":null,"HPA016616":"AB_1859004"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.43e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.37e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.81e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"}},{"Gene":"ZDHHC4","Gene synonym":["FLJ10479","ZNF374"],"Ensembl":"ENSG00000136247","Gene description":"Zinc finger DHHC-type palmitoyltransferase 4","Uniprot":["Q9NPG8"],"Chromosome":"7","Position":"6577434-6589374","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Liver - Hepatocytes","Testis - Early spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032124"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 63: Non-specific - Unknown function","Single cell expression cluster":"Cluster 40: Plasma cells - Humoral immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA032124":"AB_10610699"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.35e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.95e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.94e-4"}},{"Gene":"ZDHHC5","Gene synonym":["DHHC5","KIAA1748","ZNF375"],"Ensembl":"ENSG00000156599","Gene description":"Zinc finger DHHC-type palmitoyltransferase 5","Uniprot":["Q9C0B5"],"Chromosome":"11","Position":"57667747-57701182","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Innate immunity","Lipid transport","Transport"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)","Testis - Early spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014670"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA014670":"AB_2257442"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.74e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"}},{"Gene":"ZDHHC6","Gene synonym":["FLJ21952","ZNF376"],"Ensembl":"ENSG00000023041","Gene description":"Zinc finger DHHC-type palmitoyltransferase 6","Uniprot":["Q9H6R6"],"Chromosome":"10","Position":"112424428-112446917","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Podocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014357"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014357":"AB_2304658"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"}},{"Gene":"ZDHHC7","Gene synonym":["DHHC7","FLJ10792","FLJ20279","SERZ-B","SERZ1","ZNF370"],"Ensembl":"ENSG00000153786","Gene description":"Zinc finger DHHC-type palmitoyltransferase 7","Uniprot":["Q9NXF8"],"Chromosome":"16","Position":"84974175-85011535","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Breast - Fibroblasts"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019215","HPA059054","HPA059642"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 36: Non-specific - Unknown function","Single cell expression cluster":"Cluster 69: Macrophages - Innate immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA019215":"AB_2670102","HPA059054":"AB_2683892","HPA059642":"AB_2684093"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.20e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-2"}},{"Gene":"ZDHHC8","Gene synonym":["KIAA1292","ZNF378"],"Ensembl":"ENSG00000099904","Gene description":"Zinc finger DHHC-type palmitoyltransferase 8","Uniprot":["Q9ULC8"],"Chromosome":"22","Position":"20129456-20148007","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003422"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 39: Non-specific - Unknown function","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA003422":"AB_1080640"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.68e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.04e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-2"}},{"Gene":"ZDHHC9","Gene synonym":["CGI-89","CXorf11","DHHC9","ZDHHC10","ZNF379","ZNF380"],"Ensembl":"ENSG00000188706","Gene description":"Zinc finger DHHC-type palmitoyltransferase 9","Uniprot":["Q9Y397"],"Chromosome":"X","Position":"129803288-129843909","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"166.5","Alveolar cells type 2":"91.4","Oligodendrocytes":"111.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031814"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 41: Alveolar cells - Lung function","Subcellular main location":["Endoplasmic reticulum","Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA031814":"AB_10610700"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.77e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.45e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.70e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-2"}},{"Gene":"ZFPL1","Gene synonym":["D11S750","MCG4"],"Ensembl":"ENSG00000162300","Gene description":"Zinc finger protein like 1","Uniprot":["O95159"],"Chromosome":"11","Position":"65084210-65088398","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014909","HPA017347"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 58: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA014909":"AB_1859055","HPA017347":"AB_1859056"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.12e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.73e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"}},{"Gene":"ZFX","Gene synonym":["ZNF926"],"Ensembl":"ENSG00000005889","Gene description":"Zinc finger protein X-linked","Uniprot":["P17010"],"Chromosome":"X","Position":"24149173-24216255","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001748","HPA003877","HPA071863"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 48: Non-specific - RNA binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA001748":"AB_1080650","HPA003877":"AB_1080648","HPA071863":"AB_2686463"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"}},{"Gene":"ZFYVE27","Gene synonym":["FLJ32919","SPG33"],"Ensembl":"ENSG00000155256","Gene description":"Zinc finger FYVE-type containing 27","Uniprot":["Q5T4F4"],"Chromosome":"10","Position":"97737121-97760907","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hereditary spastic paraplegia","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037523","HPA069876"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA037523":"AB_10672351","HPA069876":"AB_2686218"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.91e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.54e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.80e-4"}},{"Gene":"ZFYVE28","Gene synonym":["KIAA1643","lst-2"],"Ensembl":"ENSG00000159733","Gene description":"Zinc finger FYVE-type containing 28","Uniprot":["Q9HCC9"],"Chromosome":"4","Position":"2269582-2418651","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"49.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"131.8","Inhibitory neurons":"91.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"49.9"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"1.8","T-cells":"1.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038175","HPA057587"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 54: Lymphoma - Cytokine signaling","Single cell expression cluster":"Cluster 38: Neurons - Neuronal signaling","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA038175":"AB_10697244","HPA057587":"AB_2683477"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-2"}},{"Gene":"ZG16B","Gene synonym":["HRPE773","JCLN2","PRO1567"],"Ensembl":"ENSG00000162078","Gene description":"Zymogen granule protein 16B","Uniprot":["Q96DA0"],"Chromosome":"16","Position":"2830169-2839585","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"717","RNA tissue specific nTPM":{"salivary gland":"63926.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Serous glandular cells":"23485.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"47.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"6.3","intermediate monocyte":"11.4","non-classical monocyte":"7.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"monocytes":"11.4"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"breast cancer":"17.8","prostate cancer":"24.1"},"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skin - Eccrine sweat gland cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041125","HPA053549"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Secreted to digestive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"690000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 65: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 21: Serous glandular cells - Salivary secretion","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA041125":"AB_10794264","HPA053549":"AB_2682184"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.48e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.33e-2"}},{"Gene":"ZMPSTE24","Gene synonym":["FACE-1","HGPS","PRO1","STE24","Ste24p"],"Ensembl":"ENSG00000084073","Gene description":"Zinc metallopeptidase STE24","Uniprot":["O75844"],"Chromosome":"1","Position":"40258041-40294180","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006988"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"50000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 18: Non-specific - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA006988":"AB_1080659"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.73e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.34e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"}},{"Gene":"ZMYM5","Gene synonym":["MYM","ZNF198L1","ZNF237"],"Ensembl":"ENSG00000132950","Gene description":"Zinc finger MYM-type containing 5","Uniprot":["Q9UJ78"],"Chromosome":"13","Position":"19823482-19863649","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015544","HPA020879"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 13: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 11: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA015544":null,"HPA020879":"AB_2670524"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"}},{"Gene":"ZMYM6","Gene synonym":["Buster2","MYM","ZBED7","ZNF198L4","ZNF258"],"Ensembl":"ENSG00000163867","Gene description":"Zinc finger MYM-type containing 6","Uniprot":["O95789"],"Chromosome":"1","Position":"34986165-35031945","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011004","HPA071865"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 66: Myeloid cells - Innate immune response","Single cell expression cluster":"Cluster 12: Non-specific - Chromatin organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA011004":"AB_1859075","HPA071865":"AB_2686464"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.30e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-3"}},{"Gene":"ZMYND11","Gene synonym":["BS69"],"Ensembl":"ENSG00000015171","Gene description":"Zinc finger MYND-type containing 11","Uniprot":["Q15326"],"Chromosome":"10","Position":"134465-254637","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell cycle","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Repressor"],"Disease involvement":["Intellectual disability","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015816"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 15: Smooth muscle cells - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015816":"AB_1845427"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.76e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"}},{"Gene":"ZMYND15","Gene synonym":["DKFZp434N127"],"Ensembl":"ENSG00000141497","Gene description":"Zinc finger MYND-type containing 15","Uniprot":["Q9H091"],"Chromosome":"17","Position":"4739833-4746119","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Differentiation","Spermatogenesis","Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"testis":"28.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"219.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Testis - Early spermatids","Testis - Late spermatids","Thyroid - T-cells"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023286"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 30: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA023286":"AB_1859076"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"}},{"Gene":"ZNF292","Gene synonym":["bA393I2.3","KIAA0530","ZFP292","Zn-15","Zn-16"],"Ensembl":"ENSG00000188994","Gene description":"Zinc finger protein 292","Uniprot":["O60281"],"Chromosome":"6","Position":"87152833-87265943","Protein class":["Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Autism spectrum disorder","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Kidney - Endothelial cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032154","HPA050618"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 12: Lymphoid cancers - Adaptive immune response","Single cell expression cluster":"Cluster 14: Endometrium - Transcription regulation","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA032154":"AB_10601930","HPA050618":"AB_2681190"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"}},{"Gene":"ZNF333","Gene synonym":["KIAA1806"],"Ensembl":"ENSG00000160961","Gene description":"Zinc finger protein 333","Uniprot":["Q96JL9"],"Chromosome":"19","Position":"14689801-14733746","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043973","HPA054680"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 53: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA043973":"AB_10961277","HPA054680":"AB_2682571"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-3"}},{"Gene":"ZNF431","Gene synonym":["KIAA1969"],"Ensembl":"ENSG00000196705","Gene description":"Zinc finger protein 431","Uniprot":["Q8TF32"],"Chromosome":"19","Position":"21142024-21196053","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"114.3","Granulosa cells":"124.7","Theca cells":"160.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059135"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059135":"AB_2683918"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"}},{"Gene":"ZNF511","Gene synonym":["MGC30006","Zfp511"],"Ensembl":"ENSG00000198546","Gene description":"Zinc finger protein 511","Uniprot":["Q8NB15"],"Chromosome":"10","Position":"133308914-133313162","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035360"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 67: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 26: Intestinal epithelial cells - Absorption","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA035360":"AB_10601931"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"}},{"Gene":"ZNF511-PRAP1","Gene synonym":[],"Ensembl":"ENSG00000283496","Gene description":"ZNF511-PRAP1 readthrough","Uniprot":[],"Chromosome":"10","Position":"133309410-133352529","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"intestine":"9.2","kidney":"8.4","liver":"30.4"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":null,"RNA cancer distribution":null,"RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035360","HPA038713","HPA052451"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Nuclear bodies","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":null,"Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"HPA035360":"AB_10601931","HPA038713":"AB_10673117","HPA052451":"AB_2681839"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ZNF584","Gene synonym":["FLJ39899"],"Ensembl":"ENSG00000171574","Gene description":"Zinc finger protein 584","Uniprot":["Q8IVC4"],"Chromosome":"19","Position":"58401504-58418327","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skin - Keratinocyte (other)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043408","HPA048075"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 56: Ciliated cells - Cilium assembly","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA043408":"AB_2678466","HPA048075":"AB_2680251"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"}},{"Gene":"ZNF609","Gene synonym":["KIAA0295"],"Ensembl":"ENSG00000180357","Gene description":"Zinc finger protein 609","Uniprot":["O15014"],"Chromosome":"15","Position":"64460742-64686068","Protein class":["Predicted intracellular proteins"],"Biological process":["Myogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"119.6","Excitatory neurons":"140.1","Inhibitory neurons":"113.7","Microglial cells":"135.9","Oligodendrocytes":"196.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Spermatocytes"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040742","HPA040832"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 45: Non-specific - Cell proliferation","Single cell expression cluster":"Cluster 8: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA040742":"AB_10963581","HPA040832":"AB_10960400"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"}},{"Gene":"ZNF618","Gene synonym":["KIAA1952","NEDD10"],"Ensembl":"ENSG00000157657","Gene description":"Zinc finger protein 618","Uniprot":["Q5T7W0"],"Chromosome":"9","Position":"113876282-114056591","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023116","HPA061732"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 23: B-cell cancers - Adaptive immune response","Single cell expression cluster":"Cluster 9: Neurons - Nervous system development","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA023116":"AB_10964204","HPA061732":"AB_2684596"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.34e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.22e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"}},{"Gene":"ZNF628","Gene synonym":["ZEC","Zfp628"],"Ensembl":"ENSG00000197483","Gene description":"Zinc finger protein 628","Uniprot":["Q5EBL2"],"Chromosome":"19","Position":"55476617-55484487","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"23.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"116.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044451"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 51: Late spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA044451":"AB_10962507"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-3"}},{"Gene":"ZNF629","Gene synonym":["KIAA0326","ZNF65"],"Ensembl":"ENSG00000102870","Gene description":"Zinc finger protein 629","Uniprot":["Q9UEG4"],"Chromosome":"16","Position":"30778456-30787205","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"27.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Sertoli cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019550","HPA056051"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 8: Non-specific - Transcription","Single cell expression cluster":"Cluster 77: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA019550":"AB_1859386","HPA056051":"AB_2683020"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.57e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"}},{"Gene":"ZNF654","Gene synonym":["FLJ10997","FLJ21142"],"Ensembl":"ENSG00000175105","Gene description":"Zinc finger protein 654","Uniprot":[],"Chromosome":"3","Position":"88059255-88144660","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"9.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036172","HPA036173","HPA049262","HPA077939"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Microtubules","Cytokinetic bridge","Mitotic spindle"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 5: Non-specific - Unknown function","Single cell expression cluster":"Cluster 75: Myeloid cells - Innate immune response","Subcellular main location":["Microtubules"],"Subcellular additional location":["Nucleoplasm","Cytokinetic bridge","Mitotic spindle"],"Antibody RRID":{"HPA036172":"AB_10672081","HPA036173":"AB_2674987","HPA049262":null,"HPA077939":"AB_2732364"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.97e-6"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"}},{"Gene":"ZNF66","Gene synonym":["FLJ16537","ZNF66P"],"Ensembl":"ENSG00000160229","Gene description":"Zinc finger protein 66","Uniprot":["Q6ZN08"],"Chromosome":"19","Position":"20776304-20809995","Protein class":["Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"24.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"19.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"18.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"18.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 52: Spermatids - Smell perception","Single cell expression cluster":"Cluster 17: Granulosa cells - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"}},{"Gene":"ZNF695","Gene synonym":["SBZF3"],"Ensembl":"ENSG00000197472","Gene description":"Zinc finger protein 695","Uniprot":["Q8IW36"],"Chromosome":"1","Position":"246945547-247008093","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"3.2","Extravillous trophoblasts":"3.9","Spermatocytes":"3.0","Spermatogonia":"2.5","Undifferentiated cells":"3.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"2.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Mitotic cells (Stomach)"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024743"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 43: Non-specific - Cell proliferation","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA024743":"AB_1859419"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-5"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"}},{"Gene":"ZNF7","Gene synonym":["HF.16","KOX4"],"Ensembl":"ENSG00000147789","Gene description":"Zinc finger protein 7","Uniprot":["P17097"],"Chromosome":"8","Position":"144827464-144847509","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059090"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 64: Non-specific - Transcription","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA059090":"AB_2683901"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.46e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"}},{"Gene":"ZNF787","Gene synonym":[],"Ensembl":"ENSG00000142409","Gene description":"Zinc finger protein 787","Uniprot":["Q6DD87"],"Chromosome":"19","Position":"56087366-56121295","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"143.0","Endometrial ciliated cells":"88.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035140"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 16: Non-specific - RNA binding","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Mitochondria"],"Antibody RRID":{"HPA035140":"AB_10602358"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"}},{"Gene":"ZNF85","Gene synonym":["HPF4","HTF1"],"Ensembl":"ENSG00000105750","Gene description":"Zinc finger protein 85","Uniprot":["Q03923"],"Chromosome":"19","Position":"20923222-20950697","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Repressor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Early spermatids":"166.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044760"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 57: Early spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA044760":"AB_10960412"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.20e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.45e-6"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"}},{"Gene":"ZNF875","Gene synonym":["HKR1"],"Ensembl":"ENSG00000181666","Gene description":"Zinc finger protein 875","Uniprot":["P10072"],"Chromosome":"19","Position":"37312837-37369365","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"141.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"125.8","Rod photoreceptor cells":"145.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Testis - Sertoli cells"],"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036126","HPA044855"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 44: Photoreceptor cells - Visual perception","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA036126":"AB_10670708","HPA044855":"AB_2679113"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.41e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.18e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"}},{"Gene":"ZNRF1","Gene synonym":["DKFZp434E229","FLJ14846","nin283"],"Ensembl":"ENSG00000186187","Gene description":"Zinc and ring finger 1","Uniprot":["Q8ND25"],"Chromosome":"16","Position":"74999024-75110994","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"74.1","granulocytes":"105.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"2.4","T-reg":"2.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"2.4","T-cells":"2.4"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes","Skin - Keratinocyte (other)","Testis - Late spermatids","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027470"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 62: Granulocytes - Innate immune response","Single cell expression cluster":"Cluster 46: Granulocytes - Mast cell degranulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA027470":"AB_10603108"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.90e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"}},{"Gene":"ZNRF3","Gene synonym":["BK747E2.3","FLJ22057","KIAA1133","RNF203"],"Ensembl":"ENSG00000183579","Gene description":"Zinc and ring finger 3","Uniprot":["Q9ULT6"],"Chromosome":"22","Position":"28883572-29057488","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Developmental protein","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"488.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Thyroid - Thyroid glandular cells"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036702","HPA036703"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 2: DU4475 - Unknown function","Single cell expression cluster":"Cluster 63: Astrocytes - Nervous system maintenance","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA036702":null,"HPA036703":"AB_10672227"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"}},{"Gene":"ZNRF4","Gene synonym":["RNF204","spzn","Ssrzf1"],"Ensembl":"ENSG00000105428","Gene description":"Zinc and ring finger 4","Uniprot":["Q8WWF5"],"Chromosome":"19","Position":"5455417-5456856","Protein class":["Enzymes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"905","RNA tissue specific nTPM":{"testis":"120.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"79","RNA single cell type specific nTPM":{"Early spermatids":"554.6","Late spermatids":"667.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 32: Myeloid leukemia - Oxygen transport","Single cell expression cluster":"Cluster 49: Early spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ZP1","Gene synonym":[],"Ensembl":"ENSG00000149506","Gene description":"Zona pellucida glycoprotein 1","Uniprot":["P60852"],"Chromosome":"11","Position":"60867562-60875693","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Fertilization"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"No human protein\/transcript evidence","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Early spermatids":"30.2","Late spermatids":"87.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"0.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"32","RNA blood cell specific nTPM":{"plasmacytoid DC":"3.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"dendritic cells":"3.1"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Skin - Sebaceous gland cells","Testis - Early spermatids","Testis - Late spermatids"],"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in female reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: Non-specific - Cilium assembly","Single cell expression cluster":"Cluster 6: Late spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"}},{"Gene":"ZP2","Gene synonym":["ZPA"],"Ensembl":"ENSG00000103310","Gene description":"Zona pellucida glycoprotein 2","Uniprot":["Q05996"],"Chromosome":"16","Position":"21197450-21214510","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Fertilization"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"4.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Proximal enterocytes":"6.8","Serous glandular cells":"2.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"15","RNA brain regional specific nTPM":{"cerebellum":"4.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011296"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in female reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 11: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA011296":"AB_1859485"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ZP3","Gene synonym":["ZP3-372","ZP3-424","ZP3A","ZP3B","ZPC"],"Ensembl":"ENSG00000188372","Gene description":"Zona pellucida glycoprotein 3","Uniprot":["P21754"],"Chromosome":"7","Position":"76397518-76442071","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Fertilization"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"72.0","Early spermatids":"26.5","Ionocytes":"29.9","Late spermatids":"63.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"50.6"},"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054061","HPA071198"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in female reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":"Cluster 5: Bronchus - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054061":"AB_2682363","HPA071198":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.02e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"}},{"Gene":"ZP4","Gene synonym":["ZPB"],"Ensembl":"ENSG00000116996","Gene description":"Zona pellucida glycoprotein 4","Uniprot":["Q12836"],"Chromosome":"1","Position":"237877864-237890922","Protein class":["Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Fertilization"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008547"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in female reproductive system","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 44: Myeloma - Humoral immune response","Single cell expression cluster":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008547":"AB_1080766"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null},{"Gene":"ZPLD1","Gene synonym":[],"Ensembl":"ENSG00000170044","Gene description":"Zona pellucida like domain containing 1","Uniprot":["Q8TCW7"],"Chromosome":"3","Position":"102099244-102479841","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1.6","gallbladder":"2.2","retina":"2.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"5.8","Ductal cells":"3.6","Exocrine glandular cells":"3.8","Late spermatids":"6.2","Muller glia cells":"14.9","Pancreatic endocrine cells":"6.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"20","RNA cell line specific nTPM":{"Rhabdoid":"38.2"},"RNA tissue cell type enrichment":["Colon - Colon enteroendocrine cells"],"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"olfactory bulb":"2.8"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA077519"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 22: Rhabdoid cancers - Neuronal signaling","Single cell expression cluster":"Cluster 68: Muller glia cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA077519":"AB_2732349"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"}},{"Gene":"ZSWIM9","Gene synonym":["C19orf68","LOC374920"],"Ensembl":"ENSG00000185453","Gene description":"Zinc finger SWIM-type containing 9","Uniprot":["Q86XI8"],"Chromosome":"19","Position":"48170680-48197620","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"18.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"32.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA061028"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 4: Non-specific - Transcription","Single cell expression cluster":"Cluster 36: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA061028":"AB_2684419"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.35e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.44e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"}},{"Gene":"ZZEF1","Gene synonym":["FLJ10821","KIAA0399","ZZZ4"],"Ensembl":"ENSG00000074755","Gene description":"Zinc finger ZZ-type and EF-hand domain containing 1","Uniprot":["O43149"],"Chromosome":"17","Position":"4004445-4143030","Protein class":["Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"97.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031778","HPA031790"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 49: Non-specific - Unknown function","Single cell expression cluster":"Cluster 59: Proximal enterocytes - Transmembrane transport","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"HPA031778":"AB_10599831","HPA031790":"AB_10600999"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.08e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.46e-2"}}]